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Ua12/2/1 College Heights Herald: Ways Of The Future, Wku Student Affairs

WKU Administration Documents

Magazine edition of the College Heights Herald for the period April 8 - May 5, 2024.

• Anderson, Alexandria. Letter from the Editor – Science, Technology & Business
• Anderson, Alexandria. Women in STEM Make Advances
• Novoselia, Mariia. Turnover on Fountain Square: Local Businesses Share Concerns & Success Stories
• SOKY Rentals Offers New Apartments
• Walk2Campus: Where Home Meets Community
• Bush, Camden. Can a Baseball Team Reduce Their Goals to a Math Problem?
• Hawkins, Kaylee. Student Business Owners Share Experiences – Gatara Townsend, Andrew Garrett, Brittiny Sadler
• Ivory, Larkin. Bikewalk BG, WKU CHHS Offer Chances for Healthy Lifestyle – Health & Human Services

Synthesis And Characterization Of Ox-Nad Derivatives, Juanita Monteiro-Pai

Honors Theses

Energy metabolism is complex, and NAD, or nicotinamide adenine dinucleotide, plays a huge role as an organic redox cofactor, driving metabolic reactions. The abundance of pathways dependent on NAD has led to an increase in the studies of NAD and its precursors. As a result NR, or nicotinamide riboside, is now a popular pharmaceutical taken to increase levels of NAD in the body. NR is not only a precursor to NAD, but a metabolite that is found in extracellular regions such as urine and blood. While this molecule should be an intracellular molecule, the fact that it is found in …

Impacts Of Hurricane Idalia’S Surge On Coastal Sand Biogeochemistry, Wendy "Cor" Mchone

Honors Theses

Beaches are heavily influenced by extreme events, such as hurricanes. Biological and chemical processes, such as primary production and diagenesis are often interrupted by these events. To examine the effects of hurricanes on coastal biogeochemistry, this study used sand and porewater samples from Waties Island, SC, which were collected before and after Hurricane Idalia. The samples were analyzed for macronutrient concentrations, organic content, and chlorophyll concentrations. Macronutrient pore water concentration changes were not uniform. The inventory of nitrite decreased significantly after the storm, which was reflected in slight increases in the inventories of nitrate and ammonium. Concentrations of nitrate, which …

The Relationship Between Amygdala And Orbitofrontal Cortex Volume In The Context Of Oppositional Defiant Disorder, Rahul Alla

Honors Scholar Theses

Disobedient and rebellious attitude in children is on the rise and this type of behavior is categorized as Oppositional Defiant Disorder (ODD). ODD in children can be identified as a persistent pattern of angry or irritable mood, argumentative or defiant behavior or vindictiveness toward others according to the Diagnostic and Statistical Manual (DSM-5, Fifth Edition) of Mental Disorders.1 Children with ODD typically have difficulty regulating and processing their emotions. Issues with regulating emotions is defined as the process by which individuals “influence which emotions they have, when they have them, and how they experience and express them”.2 Dysregulation of emotions …

Investigating The Impact Of Secondary Activation Time On The Adsorption Properties Of Activated Biochar For Arsenic Removal From Wastewater, Achyuth Bharadwaj Rayarao

Graduate Theses and Dissertations (2019 - present)

Biochar, a naturally occurring and renewable carbon material, becomes porous through activation. Activated biochar is an ideal candidate for use as an adsorbent. The objective of this study is to investigate whether activated biochar derived from Colorado soft pine serves as a better adsorbent and demonstrates enhanced adsorption capabilities after undergoing secondary physical activation at various activation times. The effect of secondary action time on physical adsorption properties drawn from the analysis of isotherm plots, surface areas and pore size patterns were examined by using a physisorption analyzer. Chemical structures were identified using both ultimate and proximate analyses, while porosity …

Identifying Phytoremediation Performing Plant Species That Can Be Utilized In The Improvement Of Heavy Metal Contaminated Soils, Ashley Clark*, Samuel Mutiti

Graduate Research Showcase

Heavy metal pollution is a problem associated with industrialization and development. Two major metals that are commonly mined and can enter the environment, which can jeopardize communities’ health, are copper (Cu) and lead (Pb). There are different options for reducing heavy metal pollution in the environment via remediation efforts, including physical, chemical, and biological methods. However, physical and chemical remediation can be costly and labor-intensive, making them unsuitable for regions that do not have the funds to utilize these practices. Biological remediation is a more cost-conservative practice that has been shown in many studies to be effective in the gradual …

Identifying High-Value Tactical Livestock Decisions On A Mixed Enterprise Farm In A Variable Environment, Michael Young, John Young, Ross S. Kingwell, Philip E. Vercoe

Animal production and livestock research articles

Context

Australia is renowned for its climate variation, featuring years with drought and years with floods, which result in significant production and profit variability. Accordingly, to maximise profitability, dryland farming systems need to be dynamically managed in response to unfolding weather conditions.

Aims

The aim of this study is to identify and quantify optimal tactical livestock management for different weather-years.

Methods

This study employed a whole-farm optimisation model to analyse a representative mixed enterprise farm located in the Great Southern region of Western Australia. Using this model, we investigated the economic significance of five key livestock management tactics. These included …

Using Student Interests To Explore Inclusion In Undergraduate Chemistry, Sonja Hoversten

CSB and SJU Distinguished Thesis

For students who are not chemistry majors, but who are on a career track requiring four chemistry courses, taking the final reactivity chemistry course (CHEM 251) for pre-health students can be daunting. For this reason, this research is focused on the CHEM 251 course at The College of Saint Benedict and Saint John’s University (CSBSJU) which is one of the four required chemistry courses for pre-medicine and some pre-physician assistant students, and all chemistry and biochemistry majors. Student perception of inclusion in the course increased through the implementation of group assignments including prompts for individual application of the material. The …

Representations Of Gender In Math-Related Films, Jacob Gathje

CSB and SJU Distinguished Thesis

This project analyzes how four popular math-related films - Hidden Figures, Mean Girls, Good Will Hunting, and A Beautiful Mind - either follow, resist, or reconfigure gender stereotypes in mathematics. It includes close readings of specific scenes in each of the films, along with broader analysis of the effects of how women and men are represented differently. It concludes forward-looking focus, providing suggestions for how future math-related movies can depict a more realistic and inclusive version of the field of mathematics. Ideally, this will help improve one part of the larger issue of gender disparities in math.

Bioactive Glass Bead Characterization: Further Applications In Passive Drug Delivery, Marie O. Sykes

Physics and Astronomy Honors Papers

Bioactive glass beads were discovered for their bone repair properties in 1969. This properties, along with their bactericidalness, high ability to be engineered, bioactiveness and their versatile structures, mark them as excellent candidates for explorations in other biomedical applications in addition to bone repair. One alternative application includes passive drug delivery, especially when the biomaterial is in a porous, microsphere structure. In this work, we first explore various samples of bioactive glass compositions and structures in order to target the best bead for the application of drug delivery. The targeted beads are then thoroughly characterized using optical microscopy, Scanning Electron …

Design, Synthesis, Self-Assembly, And Applications Of Functional Bottlebrush Architectures Through Ring-Opening Metathesis Polymerization, Yipei Zhang

Arts & Sciences Graduate Student Theses and Dissertations

Shear-thinning hydrogels are a class of materials with unique rheological properties that enable them to undergo a reversible reduction in viscosity under shear stress, which allows for easy injection. The injectability of shear-thinning hydrogels is particularly important when considering their use in biomedical applications, such as drug delivery, tissue engineering, and wound healing. However, before advancing to these applications, it is crucial to evaluate the “injectability” of new shear-thinning hydrogels to avoid clogging of the needle for injection. Injectability is typically associated with determining suitable viscosity, storage/loss moduli, and other factors, such as injection force (e.g., needle length and gauge …

Analytical And Numerical Analysis Of The Sirs Model, Catherine Nguyen

Departmental Honors & Graduate Capstone Projects

Mathematical models in epidemiology describe how diseases affect and spread within a population. By understanding the trends of a disease, more effective public health policies can be made. In this paper, the Susceptible-Infected-Recovered-Susceptible (SIRS) Model was examined analytically and numerically to compare with the data for Coronavirus Disease 2019 (COVID-19). Since the SIRS model is a complex model, analytical techniques were used to solve simplified versions of the SIRS model in order to understand general trends that occur. Then by Euler's Method, the Runge-Kutta Method, and the Predictor-Corrector Method, computational approximations were obtained to solve and plot the SIRS model. …

Incorporating Solvent Effects In Dft: Insights From Cation Exchange In Faujasites, An T. Ta, Ayoub Daouli, R. Seaton Ullberg, Eric Fonseca, Vanessa Proust, Agnès Grandjean, Richard G. Hennig, Hans Conrad Zur Loye, Michael Badawi, Simon R. Phillpot

Faculty Publications

Zeolites are versatile materials renowned for their extra-framework cation exchange capabilities, with applications spanning diverse fields, including nuclear waste treatment. While detailed experimental characterization offers valuable insight, density functional theory (DFT) proves particularly adept at investigating ion exchange in zeolites, owing to its atomic and electronic resolution. However, the prevalent occurrence of zeolitic ion exchange in aqueous environments poses a challenge to conventional DFT modeling, traditionally conducted in a vacuum. This study seeks to enhance zeolite modeling by systematically evaluating predictive differences across varying degrees of aqueous solvent inclusion. Specifically focusing on monovalent cation exchange in Na-X zeolites, we explore …

Star-Based Reachability Analysis Of Binary Neural Networks On Continuous Input, Mykhailo Ivashchenko

School of Computing: Dissertations, Theses, and Student Research

Deep Neural Networks (DNNs) have become a popular instrument for solving various real-world problems. DNNs’ sophisticated structure allows them to learn complex representations and features. However, architecture specifics and floating-point number usage result in increased computational operations complexity. For this reason, a more lightweight type of neural networks is widely used when it comes to edge devices, such as microcomputers or microcontrollers – Binary Neural Networks (BNNs). Like other DNNs, BNNs are vulnerable to adversarial attacks; even a small perturbation to the input set may lead to an errant output. Unfortunately, only a few approaches have been proposed for verifying …

Rosarugosides A And D From Osa Rugosa Flower Buds: Their Potential Anti-Skin-Aging Effects Intnf-Α-Induced Human Dermal Fibroblasts, Kang Sub Kim, So-Ri Son, Yea Jung Choi, Yejin Kim, Si-Young Ahn, Dae Sik Jang, Sullim Lee

Faculty, Staff and Student Publications

This present study investigated the anti-skin-aging properties of Rosa rugosa. Initially, phenolic compounds were isolated from a hot water extract of Rosa rugosa's flower buds. Through repeated chromatography (column chromatography, MPLC, and prep HPLC), we identified nine phenolic compounds (1-9), including a previously undescribed depside, rosarugoside D (1). The chemical structure of 1 was elucidated via NMR, HR-MS, UV, and hydrolysis. Next, in order to identify bioactive compounds that are effective against TNF-α-induced NHDF cells, we measured intracellular ROS production in samples treated with each of the isolated compounds (1- …

Near-Collapse Of The Geomagnetic Field May Have Contributed To Atmospheric Oxygenation And Animal Radiation In The Ediacaran Period, Wentao Huang, John A. Tarduno, Tinghong Zhou, Mauricio Ibañez-Mejia, Laércio Dal Olmo-Barbosa, Edinei Koester, Eric G. Blackman, Aleksey V. Smirnov, Gabriel Ahrendt, Rory D. Cottrell, Kenneth P. Kodama, Richard K. Bono, David G. Sibeck, Yong Xiang Li, Francis Nimmo, Shuhai Xiao, Michael K. Watkeys

Michigan Tech Publications

Earth’s magnetic field was in a highly unusual state when macroscopic animals of the Ediacara Fauna diversified and thrived. Any connection between these events is tantalizing but unclear. Here, we present single crystal paleointensity data from 2054 and 591 Ma pyroxenites and gabbros that define a dramatic intensity decline, from a strong Proterozoic field like that of today, to an Ediacaran value 30 times weaker. The latter is the weakest time-averaged value known to date and together with other robust paleointensity estimates indicate that Ediacaran ultra-low field strengths lasted for at least 26 million years. This interval of ultra-weak magnetic …

Zeolitic Imidazolate Framework-8 Encapsulated With Mo-Based Polyoxometalates As Surfaces With Antibacterial Activity Against Escherichia Coli, Mariam M. Abdelkhalek, Aya M. Mohamed, Rehab Z. Abdallah, Ghada E. Khedr, Rania Siam, Nageh K. Allam

Faculty Journal Articles

Bacterial infections represent a major global health concern, causing millions of deaths and a significant economic burden. The development of antibacterial nanoporous surfaces with potential mechano-bactericidal effects can revolutionize infection control practices. In this study, a hybrid material of zeolitic imidazolate framework-8 (ZIF-8) doped with phosphomolybdic acid (PMA) was synthesized and characterized by field emission scanning electron microscopy (FESEM), energy-dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), and N2 sorption isotherms. PMA@ZIF-8 performance as an antibacterial agent against E. coli was superior to that of its individual constituents, suggesting a synergistic effect of PMA and ZIF-8. The …

Characterizing Potentially Harmful Environmental Legacy Issues Within A Declining Midwest City: A Street Sediment Study Of Northeastern Terre Haute, Indiana, Katelyn Adams '24, Ken Brown

Senior Scholarly and Creative Symposium

Urban settings face unprecedented environmental challenges that include legacy issues as well as emerging pollution problems (e.g., micro-plastics) that continually impact the public health of its communities. Determining the baseline abundances of potentially harmful contaminants in soil, sediment, air, and water is essential to protecting residents. This study examines anthropogenic pollution in street sediments collected from three neighborhoods located in northeast Terre Haute, Indiana. Using stereomicroscopy, SEM/EDS, pXRF analyses, and geospatial analysis (GIS), the goal of this work is to characterize the types of pollutants present and place important constraints on their potential sources.

Stereomicroscopy on nine street sediment samples …

Measurement Of Transmission Efficiency Of Blue Light Blocking Devices, Jada Lee

Honors Theses

Technology and light sources have experienced a revolution in recent years leading to the production of light emitting diode (LED) bulbs. White-light LED bulbs undergo degradation over time, leading to a rise in color temperature and a proportional increase in the emission of blue light from these bulbs. The small size of LEDs makes them the optimal choice for electronic devices because of their limited screen size. This means that blue light now exists in red, green, and blue solid-state illumination systems that did not exist a decade ago. It is debated if blue light induces toxic effects on the …

Understanding The Public Reaction To Major United States Environmental Policies Through Twitter, Ryan Giammarco

Honors Projects in Data Science

An increased focus on access to general data as well as a continued lack of usable environmental data have resulted in an odd phenomenon where the public does not have the opportunity to understand their environment on a deep level. The goal of this research is to understand, as a result, how people both talk and feel about certain environmental changes, particularly those in the realm of politics. Through word clouds and sentiment analysis performed with historical Twitter data collected between 2010 and 2022, we can identify the general trends in both conversation and feeling as they relate to a …

Advancing Sentiment Analysis Through Emotionally-Agnostic Text Mining In Large Language Models (Llms), Jay Ratican, James Hutson

Faculty Scholarship

The conventional methodology for sentiment analysis within large language models (LLMs) has predominantly drawn upon human emotional frameworks, incorporating physiological cues that are inherently absent in text-only communication. This research proposes a paradigm shift towards an emotionallyagnostic approach to sentiment analysis in LLMs, which concentrates on purely textual expressions of sentiment, circumventing the confounding effects of human physiological responses. The aim is to refine sentiment analysis algorithms to discern and generate emotionally congruent responses strictly from text-based cues. This study presents a comprehensive framework for an emotionally-agnostic sentiment analysis model that systematically excludes physiological indicators whilst maintaining the analytical depth …

The Effects Of Free Volume And Processing On The Development Of Gas Separation Membranes, Jacob Schekman

Dissertations

Structure, thermal, mechanical, gas transport, and free volume properties of thiol-ene based systems are investigated and discussed. In the pursuit of generating low energy-cost polymer membranes for gas separation, it became apparent that UV-curing of thiol-ene materials presented several routes toward achieving this goal. Network structure plays a vital role in determining the gas transport properties of membrane materials. UV photopolymerization techniques provide a means to rapidly vitrify network morphologies which can be tuned depending on choice of monomer. Thiol-ene monomers offer a broad range of precursor materials from which to choose for the design of functional membrane materials.

Chapter …

Greening The Green: Examining The Resource Use Of Golf Courses With Suggestions On How To Improve Their Sustainability, Kaelan Addison Lestock '24

Honor Scholar Theses

Golf is a journey full of challenges, requiring each player to strive for precision, rather than merely a game of getting a small, dimpled ball in a cup hundreds of yards away in the fewest strokes possible The game is both physical and mental; it tests one’s focus, decision making, and resilience. Those who play competitively rarely feel as though they are competing against another player, instead their opponent is the course. And for those who play recreationally, the game can be a time to reconnect with nature, foster both old and new friendships, or enjoy the pursuit for perfection. …

Exploring The Role Of Gender, Race, First-Year College Gpa And Passing Stem Advanced Placement Exams And The Likelihood Of Graduating With A Stem Degree: A Multiple Logistic Regression Analysis, Amar Patel

Masters Theses & Specialist Projects

Science, Technology, Engineering, and Mathematics (STEM) careers are projected to grow beyond the normal pace of job growth (Bureau of Labor Statistics, 2021). Many of these careers will require degrees in STEM fields, but, currently, there is a significant underrepresentation of Blacks and females in both STEM degree programs and careers. The purpose of the current quantitative study was to explore the strength of the association between AP Exams, first-year GPA, race, and gender in science achievement. Research Question 1 investigated the relationship between taking AP Exams and the time taken to graduate. For students who took an AP Exam, …

Synthesis Of Poly-N-Methylated Peptides Against Malaria, Kaitlyn Watson

Theses & Dissertations

Malaria, a life-threatening global health concern, is primarily targeted by mainstream treatments such as artemisinin-based combination therapies, focusing on the blood stage of the disease. Primaquine, one of the few drugs active against the liver stage, faces challenges with reports of resistance in Plasmodium vivax strains and relapsing infections. With the scarcity of liver-stage-targeting drugs and increasing cases of drug-resistant malaria, the World Health Organization emphasizes the urgent need for novel therapeutic agents. Marine organisms are a rich source of new bioactive compounds, and extracts from the Antarctic Sea sponge Inflatella coelosphaeroides revealed new N-methylated peptides exhibiting promising antimalarial activity, …

An Exploration Of Procedural Methods In Game Level Design, Hector Salinas

Computer Science and Computer Engineering Undergraduate Honors Theses

Video games offer players immersive experiences within intricately crafted worlds, and the integration of procedural methods in game level designs extends this potential by introducing dynamic, algorithmically generated content that could stand on par with handcrafted environments. This research highlights the potential to provide players with engaging experiences through procedural level generation, while potentially reducing development time for game developers.

Through a focused exploration on two-dimensional cave generation techniques, this paper aims to provide efficient solutions tailored to this specific environment. This exploration encompasses several procedural generation methods, including Midpoint Displacement, Random Walk, Cellular Automata, Perlin Worms, and Binary Space …

Sustainable Service Trends In Restaurants, Suruchi Bhatt

School of Business

Being Sustainable is an essential milestone in the food industry. Companies form and fall because of consumers' reactions to the industry. The food industry and restaurants account for some of the highest Food Waste and Pollution, approximately 34% of the Global anthropogenic greenhouse gas emissions, including food production, processing, distribution, and consumption. (Crippa et al., 2021) In a sector like this, ensuring a complete understanding of sustainability in the industry is of utmost importance. However, the sheer relationship between the sustainable image, the prospect of sustainability, and the reality of implementing it may be far from reality. (Yuying-Huang, 2022)

Grey Relational Analysis And Canonical Correlation Analysis Of Air Pollution In Three Kentucky Counties, Sarah Hartman

Masters Theses & Specialist Projects

Air pollution is a crucial factor that affects both the environment and public health. Various methods are available for assessing air quality and pollution levels, such as regression models, principal component analysis, and factor analysis tools. However, some of these methods present issues in multicollinearity and the nature of collected data. It is important to recognize that air pollution data is often uncertain, incomplete, and contains limited valid data points. Weather conditions and economic activities are also factors that can affect air pollution. With growing communities in Kentucky (KY), it is essential to address these factors as the state has …

Development Of An Enhanced Sampling Workflow To Accelerate Molecular Docking With Sparse Biophysical Information, Zachary Stichter

Masters Theses & Specialist Projects

Rapid docking of flexible biological macromolecules remains a significant open challenge in protein structure determination. While rigid docking is relatively simple with toolkits such as TagDock, a key obstacle to rapid flexible docking is the complexity and roughness of the free energy surface associated with protein conformational motion (often termed the many-minima problem), meaning conventional molecular dynamics methods do not effectively sample protein conformations near the interaction complex in accessible timescales. Methods such as metadynamics and replica exchange molecular dynamics exist to ameliorate this obstacle, yet these methods use nonphysical biases or random swaps to enhance sampling. In contrast, high …

Synthesis Of Gold Nanoparticles Via Pulsed Liquid Ablation For Use In The Photodynamic Therapy Of Bacteria, Justice Ben Yosef

Masters Theses & Specialist Projects

With the ever-increasing threat of antibiotic resistant bacteria, alternative treatment methods have been developed including photodynamic therapy (PDT). Within the PDT process, photosensitizers are used to generate reactive oxygen species (ROS) and facilitate the cell termination process. This work lays the conceptual foundation for the functionalization of the photosensitizer methylene blue (MB) with gold nanoparticles (AuNPs) and INF-55 as a potential inhibitor of the AcrAB-TolC efflux pump to enhance the effectivity of the PDT process.

AuNPs were synthesized using pulsed laser ablation in an aqueous citrate solution. Both nanosecond and picosecond pulse durations, as well as both 532 nm and …