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Decision Analysis And Fda Drug Review: A Proposal For Shadow Advisory Committees, John M. Mendeloff Jun 1995

Decision Analysis And Fda Drug Review: A Proposal For Shadow Advisory Committees, John M. Mendeloff

RISK: Health, Safety & Environment (1990-2002)

The FDA seems to acknowledge that sometimes different standards of proof for assessing drug efficacy should be used. Dr. Mendeloff thus proposes a methodology that might illuminate the FDA's decision-making and help better to assess its decisions.


Assessment Of Effectiveness Of Buffer Zones In Removing Impurities In Runoff From Areas Treated With Poultry Litter. Part Ii: Source Areas To Buffer Areas Ratio Effects, P. Srivastava, D. R. Edards, T. C. Daniel Jun 1995

Assessment Of Effectiveness Of Buffer Zones In Removing Impurities In Runoff From Areas Treated With Poultry Litter. Part Ii: Source Areas To Buffer Areas Ratio Effects, P. Srivastava, D. R. Edards, T. C. Daniel

Arkansas Water Resources Center Technical Reports

Vegetative filter strips (VFS) are known to reduce runoff losses of nutrients. solids. and other materials from land areas treated with fertilizers . Although VFS effectiveness is known to depend partially on the relative lengths of filter and pollutant source areas. there is little experimental evidence available to quantify this dependence. This is particularly the case when VFS are implemented down-slope of pasture areas treated with animal manures such as poultry litter. This study assessed the influences of pollutant source area (treated with poultry litter) and VFS lengths on VFS removal of total Kjeldahl nitrogen (TKN). ammonia nitrogen (NH3 -N …


The Prairie Naturalist Volume 27, No.2. June 1995 Jun 1995

The Prairie Naturalist Volume 27, No.2. June 1995

The Prairie Naturalist

WILDLIFE MORTALITY ASSOCIATED WITH OIL PITS IN WYOMING ▪ B.J. Esmoil and S.H. Anderson

DRAMATIC INCREASE OF LE CONTE'S SPARROW IN CONSERVATION RESERVE PROGRAM FIELDS IN THE NORTHERN GREAT PLAINS ▪ LD. Igl and D.H. Johnson

CHRISTMAS BIRD COUNTS FOR NORTH DAKOTA - 1994 ▪ R.N. Randall

DESCRIPTIONS OF WALLEYE STOCKS IN HIGH-ELEVATION RESERVOIRS, WYOMING ▪ T.D. Marwitz and W A. Hubert

NEW VASCULAR PLANT RECORDS FOR THE BLACK HILLS OF SOUTH DAKOTA AND WYOMING • G.E. Larson and J.R. Johnson

NOTES

A New Population of Small White Lady's-Slipper (Cypripedium candidum) in South Dakota ▪ S.E. Boettcher

Sandhill …


The Probe, Issue # 155 -- June 1995 Jun 1995

The Probe, Issue # 155 -- June 1995

The Probe: Newsletter of the National Animal Damage Control Association


Understanding the Eastern Coyote - Part II, by Thomas N. Tomsa, Jr., USDA-APHIS-ADC, Pennsylvania Book Review - "The Dirt Hole and Its Variations"
All Texas Counties Quarantined for Rabies
Ravenous Vultures Decimating Sheep & Calves on the East Coast
Four-Year-Old Dies of Rabies
The National Urban Wildlife Management Association (NUWMA) officially merged with NADCA, to create one larger, more effective organization to work for professional Animal Damage Control.
State-Endangered Species: Meaningful Management or Preservationist Politics?, by Richard B. Chipman, Wildlife Biologist, USDA-APHIS-ADC, Vermont
NADCA Membership Meeting
Trapping Weasels <
br>Jack H. Berryman 1995 Leopold Award Winner


Brine Shrimp Ecology In The Great Salt Lake, Utah, Wayne A. Wurtsbaugh Jun 1995

Brine Shrimp Ecology In The Great Salt Lake, Utah, Wayne A. Wurtsbaugh

Watershed Sciences Faculty Publications

Hypersaline lakes are noted for their simple communities which facilitate understanding ecological interactions (Williams et al. 1990; Wurtsbaugh 1992; Jellison and Melack 1988). Nevertheless, we still cannot easily predict how environmental changes will effect the population dynamics in these lakes, at least in part because even these simple ecosystems may be more complex than we .realize. Many hypersaline lakes are dominated by the brine shrimp Artemia spp. The production of brine shrimp is often very high because the terminal, saline lakes accumulate nutrients that make them rich, and because the short food chains in them (nutrients-->phytoplankton-->brine shrimp) minim …


Wright State University College Of Engineering And Computer Science Bits And Pcs Newsletter, Volume 11, Number 6, June 1995, College Of Engineering And Computer Science, Wright State University Jun 1995

Wright State University College Of Engineering And Computer Science Bits And Pcs Newsletter, Volume 11, Number 6, June 1995, College Of Engineering And Computer Science, Wright State University

BITs and PCs Newsletter

A ten page newsletter created by the Wright State University College of Engineering and Computer Science that addresses the current affairs of the college.


Water Current, Volume 27, No. 3, June 1995 Jun 1995

Water Current, Volume 27, No. 3, June 1995

Water Current Newsletter

Researchers Seek to Clean Up Hazardous Legacy of Bomb Production
From the Director: Annual Water Resources Tour Promises On-Site Education
Deep Soil Probing
Nebraska Water News
UNL Faculty Receive USGS Grants
Niobrara Study Out
Bookmarks Produced
Publication on BMPs for Wheat Available
Task Force Issues Recommendations
Festivals Effective
More and More Producers Recycle Pesticide Containers
Water Tour to Explore Central Nebraska


Examination Of Knowledge And Attitudes About Human Sexuality As Predictors Of Adolescent Sexual Behavior, Diane Waymire Jun 1995

Examination Of Knowledge And Attitudes About Human Sexuality As Predictors Of Adolescent Sexual Behavior, Diane Waymire

Loma Linda University Electronic Theses, Dissertations & Projects

This study investigated the variables influencing adolescent sexual behavior. Using cognitive learning theory, social learning theory, and social development as an organizing framework, factors influencing adolescent sexual behavior and the respondent's personal demographics were examined for their contribution to explaining adolescent decision-making about sexual activity.

A convenience sample of high school students from a Riverside county school district provided data for the study. Data was gathered by using a self-administered questionnaire. A total of 55 students from two of the three school sites within the district participated in the study during the winter quarter of 1995.

The findings of the …


Periodontal Repair In Dogs : Evaluation Of Rhbmp-2 Carriers, Lauralee Nygaard Jun 1995

Periodontal Repair In Dogs : Evaluation Of Rhbmp-2 Carriers, Lauralee Nygaard

Loma Linda University Electronic Theses, Dissertations & Projects

This study evaluated candidate carriers for recombinant human bone morphogenic protein-2 (rhBMP-2) in periodontal reconstructive surgery.

Canine demineralized bone matrix (DBM), bovine inorganic crystallene bone matrix (Bio-Oss), bovine derived microfibrillar collagen matrix (Helistat), poly (D,L-lactide-coglycolide) micropaiticles (PLGA), and polylactic acid granules (Drilac) were used with rhBMP-2 (20 (µg/100 µl implant volume) in routine critical size canine supraalveolar periodontal defects. Contralateral defects in six beagle dogs were randomly assigned to receive: DBM/rhBMP-2, DBM-control, Bio-Oss/rhBMP-2, Helistat/rhBMP-2, PLGA/rhBMP-2, or Drilac/rhBMP-2, all with autologous blood except for Helistat and PLGA. Animals were sacrificed eight weeks post-surgery and block sections of the defects were processed …


Water Resources Review - June 1995 Vol 8 No 2, Annis Water Resources Institute Jun 1995

Water Resources Review - June 1995 Vol 8 No 2, Annis Water Resources Institute

AWRI Reviews

No abstract provided.


Management Of Hospital Wastes In The United Arab Emirates, Hanan Ahmed Ali Shuwaiter Jun 1995

Management Of Hospital Wastes In The United Arab Emirates, Hanan Ahmed Ali Shuwaiter

Theses

The gradual expansion and development of new public and private medical complexes have resulted in the production of various types of wastes which include hazardous materials. Such wastes require appropriate handling and management schemes based on safer disposal methods. There are no reliable figures for quantifying the amount of medical waste generated or appropriate legislation and guidelines for handling, storage, transport and disposal of medical waste in the United Arab Emirates. No previous detailed studies have been conducted for the management of medical waste in the UAE. In general there is insufficient awareness of the health hazard associated with improper …


Physiologically-Based Pharmacokinetic Modeling Of Skin Absorption Using Dermal Subcompartments, Richard L. Bookout Jr. Jun 1995

Physiologically-Based Pharmacokinetic Modeling Of Skin Absorption Using Dermal Subcompartments, Richard L. Bookout Jr.

Theses and Dissertations

Dermal penetration of chemicals and drugs is important to both toxicologists and pharmacologists. Drug developers try to enhance and environmental professionals try to limit penetration of chemicals through the skin. Both can use predictive biologically-based mathematical models to assist in understanding the processes involved. When these models are based on physiological and biochemical parameters which can be measured in the laboratory, they can be extremely useful. Appropriately validated models based on first principles can be predictive of human exposures when the processes involved are adequately understood. In this thesis we develop four new physiologically-based pharmacokinetic (PBPK) models to predict blood …


Visual Pattern Recognition Using Neural Networks, Jenlong Moh May 1995

Visual Pattern Recognition Using Neural Networks, Jenlong Moh

Dissertations

Neural networks have been widely studied in a number of fields, such as neural architectures, neurobiology, statistics of neural network and pattern classification. In the field of pattern classification, neural network models are applied on numerous applications, for instance, character recognition, speech recognition, and object recognition. Among these, character recognition is commonly used to illustrate the feature and classification characteristics of neural networks.

In this dissertation, the theoretical foundations of artificial neural networks are first reviewed and existing neural models are studied. The Adaptive Resonance Theory (ART) model is improved to achieve more reasonable classification results. Experiments in applying the …


Analysis Of The Oxidation Of Isotox By Immobilized Bacteria, Chad Sheng May 1995

Analysis Of The Oxidation Of Isotox By Immobilized Bacteria, Chad Sheng

Theses

The purpose of this work is to show the effects of bio-oxidation of a pesticide through a spiral wound bioreactor using immobilized mixed culture bacteria. The pesticide used for this study is Isotox® and its active ingredients are acephate or O,S-dimethyl acetylphosphoramidothioate and vendex or hexakis (2-methyl-2-phenylpropyI)- distannoxane. Qualitative analysis of the product indicated presence of sulfate.

A consistent and unique DO pattern for Isotox® showed at least 4 minima, whereas phenol has only one minimum. The consistency of the DO pattern for Isotox® has been observed for over 30 injections into the bioreactor system. For both an …


A High-Bandwidth Frequency-Domain Photon Migration Instrument For Clinical Use, Steen J. Madsen, Eric R. Anderson, Richard C. Haskell, Bruce J. Tromberg May 1995

A High-Bandwidth Frequency-Domain Photon Migration Instrument For Clinical Use, Steen J. Madsen, Eric R. Anderson, Richard C. Haskell, Bruce J. Tromberg

All HMC Faculty Publications and Research

We have developed a high-bandwidth frequency-domain photon migration (FDPM) instrument which is capable of noninvasively determining the optical properties of biological tissues in near-real-time. This portable, inexpensive, diode-based instrument is unique in the sense that we employ direct diode laser modulation and avalanche photodiode detection. Diffusion models were used to extract the optical properties (absorption and transport scattering coefficients)of tissue-simulating solutions.from the 300 kHz to I GHz photon density wave data.


Transitions In Masculinity And Hemingway's Developed "Code", Daniel Polk May 1995

Transitions In Masculinity And Hemingway's Developed "Code", Daniel Polk

Honors Theses

The "Hemingway Code" is much more than two words that fit nicely together for a scholar's usage; the words signify a much deeper championing of masculinity, almost a haunting presence. For Ernest Hemingway living life every day, every moment with its fullest masculine fervor, became an obsession, a never-ending quest to be at one with the attitude of never complaining, never crying out, panicking, thinking too much, or regretting. To live a manly life in a series of tactical victories, performed with steadfast ritualistic mannerisms, is to embody masculinity, and therefore the "Hemingway Code."


Electrocrystallization Of Strongly Adherent Brushite Coatings On Prosthetic Alloys (Continuation), Jody G. Redepenning May 1995

Electrocrystallization Of Strongly Adherent Brushite Coatings On Prosthetic Alloys (Continuation), Jody G. Redepenning

Department of Chemistry: Faculty Publications

An electrolytic method for providing bone-emulating, phosphate coatings on prosthetic appliances. Such coatings serve to enhance bone furation after implantation of the appliances. The method of the invention is an electrolysis process wherein the appliance to be coated is immersed in a phosphate-containing electrolyte to serve as the cathode of the electrolysis process. When current is appIied to the electrolysis cell, the electrolyte solution, which includes calcium ions and dihydrogen phosphate ions, is caused to rapidly increase in (localized) pH proximate the cathode element. The localized pH increase creates a supersaturated local condition causing less soluble calcium phosphate salts to …


Dna Interstrand Crosslinking Efficiencies, Sequence Preferences, And Organic Syntheses Of Diepoxide Metabolites In Fixation, Sara Charnecki May 1995

Dna Interstrand Crosslinking Efficiencies, Sequence Preferences, And Organic Syntheses Of Diepoxide Metabolites In Fixation, Sara Charnecki

Honors Theses

Molecular Basis of Cancer: Cancer, a disease that has had a devastating and frightening impact on current society in the midst of a chemical revolution, represents a class of diseases comprising over 200 known types that affect various regions of the mammalian body (Farmer & Walker, 1985). This disease strikes randomly and is often diagnosed after the disease has progressed beyond present treatment capabilities. Cancer is the result of irregularities in growth, reproduction, and differentiation of cells due to pennanent flaws in genetic information. Mutations caused by environmental factors can be compounded over time to cause carcinomas of different tissues. …


Synthesis Of Nitrosyl Metallpoprphyrins, Thomas M. Braxton Jr. May 1995

Synthesis Of Nitrosyl Metallpoprphyrins, Thomas M. Braxton Jr.

McCabe Thesis Collection

Nitric oxide, NO, is a molecule with great versatility and importance. Made up of only a single atom of nitrogen and a single atom of oxygen, nitric oxide is perhaps one of the smallest paramagnetic molecules found in nature. The functions of NO in the body are not all known, but this molecule definitely plays a variety of roles. It is involved in the regulation of blood pressure, and it sometimes acts as a messenger for cells as well as a killer of them. It also is important in the defense of the body against foreign invaders. The significance of …


May 1995 May 1995

May 1995

What on Earth

What on Earth was a short-run student publication by the Providence College Environmental and Wildlife Club. (May 1995 - 4 pages total.)


Effects Of Flaming Gorge Dam Hydropower Operations On Flow And Stage In The Green River, Utah And Colorado, S.C.L Yin, United States Department Of Energy, Environmental Assessment Division, Argonne National Laboratory, J.J. Mccoy, S.C. Palmer May 1995

Effects Of Flaming Gorge Dam Hydropower Operations On Flow And Stage In The Green River, Utah And Colorado, S.C.L Yin, United States Department Of Energy, Environmental Assessment Division, Argonne National Laboratory, J.J. Mccoy, S.C. Palmer

All U.S. Government Documents (Utah Regional Depository)

No abstract provided.


The Probe, Issue #154 -- May 1995 May 1995

The Probe, Issue #154 -- May 1995

The Probe: Newsletter of the National Animal Damage Control Association


Understanding the Eastern Coyote - Part I, by Thomas N. Tomsa, Jr., USDA-APHIS-ADC, Pennsylvania
Book Review - "Red Fox: The Catlike Canine"
Goldfinches Devastate Strawberry Crop
Blast Ignited Over Frozen Gopher
Leg Traps Barred - Arizona Ranchers Worried
Helping to Make Trapping "PC"
Changing Times, by James Forbes, NADCA President
Trapping Weasels
Proceedings Available


Center For Sustainable Agricultural Systems Newsletter, May/June 1995 May 1995

Center For Sustainable Agricultural Systems Newsletter, May/June 1995

Center for Sustainable Agricultural Systems: Newsletter (1993–2000)

Contents:

What You'll See on the Sustainable Ag Tour

Clinton Administration Farm Policy

In the Seminar Spotlight: The Bioregenerative Landscape

Biopower from Agriculture

Managing Weeds in Farming Systems

Sustainable Families -- Sustainable Economies -- Sustainable Environments

Nebraska Governor Signs Alternative Energy Bill

Organic Research Grant Proposals Due July 31

Minnesota Offers Sustainable Ag Minor

Cast Conference on Sustainable Ag and the Farm Bill


Riparian Habitats Of The Central Platte As A Corridor For Dispersal Of Small Mammals In Nebraska, Thomas D. Silvia May 1995

Riparian Habitats Of The Central Platte As A Corridor For Dispersal Of Small Mammals In Nebraska, Thomas D. Silvia

School of Natural Resources: Dissertations, Theses, and Student Research

No abstract provided.


Studies Directed Toward Enantioselective Catalysis, Brian E. Jones May 1995

Studies Directed Toward Enantioselective Catalysis, Brian E. Jones

Open Access Master's Theses (through 2010)

Many organic molecules of modest size and complexity have chirality.That is, these molecules can exist in more than one stereoisomeric form.There is a strong desire to synthesize chiral compounds that exist in the form of a single stereoisomer.The method of synthesizing chiral compounds that was studied in our research employed a less than stoichiometric amount of chiral catalyst to both catalyze and control the stereochemical outcome of the reactions attempted.

A new chiral ligand was developed to be used as part of the chiral catalyst.This new ligand was used in the enantioselective Diels-Alder cycloaddition reaction and the enantioselective allylation reaction …


Federal Minimums: Insufficient To Save The Bay, Roy A. Hoagland, Jean G. Watts May 1995

Federal Minimums: Insufficient To Save The Bay, Roy A. Hoagland, Jean G. Watts

Faculty Publications

No abstract provided.


Iron-Dithiothreitol Dependent Production Of 8-Hydroxy-2'-Deoxyguanosine In Dna, David Allan Cook May 1995

Iron-Dithiothreitol Dependent Production Of 8-Hydroxy-2'-Deoxyguanosine In Dna, David Allan Cook

Undergraduate Honors Capstone Projects

Oxidative damage to DNA in a metal-thiol system was studied. Calf thymus DNA was incubated in an iron(IIl)-dithiothreitol system prepared in various buffers. Damage was measured by monitoring the production of 8-hydroxy-2'-deoxyguanosine. DNA oxidation was proportional to the concentration of dithiothreitol (DTT) in HEPES and tris(hydroxymethyl)aminomethane (Tris) buffers while it was only roughly related to DTT concentration in sodium chloride. Incubation in potassium phosphate buffer produced no damage. The results indicate that hydroxyl radicals may be generated by the iron-OTT system in HEPES, Tris, and sodium chloride, while in the phosphate buffer an iron phosphate complex may be formed which …


Behavioral Characteristics Affect Habitat Selection Of Domestic Ruminants, Cody B. Scott May 1995

Behavioral Characteristics Affect Habitat Selection Of Domestic Ruminants, Cody B. Scott

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

I evaluated some of the factors affecting livestock distribution by conducting experimental (Chapters II and III) and observational (Chapter IV) studies. In Chapter II, I described the effect of locations of familiar foods and social interactions on choice of feeding location by lambs. Lambs were exposed to a pasture as subgroups of strangers and companions with different dietary habits (i.e., three lambs that preferred milo with three lambs that preferred wheat). Milo was placed on one end and wheat on the other, about 100 m apart. Strangers typically fed in different locations, reflecting dietary preferences. Conversely, companions fed in both …


Disease And Habitat Change As Factors Associated With Mourning Dove Population Decline, William D. Ostrand May 1995

Disease And Habitat Change As Factors Associated With Mourning Dove Population Decline, William D. Ostrand

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The western mourning dove (Zenaida macroura) population has been declining since 1966. Data collected in 1951-52, in Fillmore, Utah, provided us a baseline for comparison with our study in the same area. Our approach was to determine whether a local population decline had occurred since the original data were collected, assess if trichomoniasis has impacted the local population, determine if changes in habitat structure affect foraging site selection, quantify changes in habitat, identify which habitats doves preferred, ascertain whether doves had responded to habitat change by changing food habits, and assess if changes in habitat were responsible in …


Winter Habitat Selection By American Marten (Martes Americana) In Newfoundland: Why Old Growth?, Gary S. Drew May 1995

Winter Habitat Selection By American Marten (Martes Americana) In Newfoundland: Why Old Growth?, Gary S. Drew

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Although the American marten (Martes americana) generally is recognized as an obligate late-seral species, the factors dictating this association are poorly understood. Martens were studied in Newfoundland, Yellowstone National Park, and in a captive setting. As expected, use of habitat types was not proportional to availability P < 0.001). Defoliated and late-seral conifer stands were used more than expected, while all other types indicated expected or less than expected use. Habitat selection by martens was detectable at spatial scales greater than 80 m (P < 0.001).

Newfoundland martens were radio-collared and monitored for diet activity during the winters of 1990 and 1991. A regression of the percent active fixes on temperature had a negative slope (b = -4.45, P = 0.084, n = 12), indicating that martens did not minimize their exposure to low temperatures. A log-linear model suggested …