Digital Commons Network^™

Bioremediation Of Pb And Cd Contaminated Soil By Mycorrhiza And Biochar Treatment And Its Effect On Growth And Yield Of Shallot, Okti Herliana, Wilis Cahyani, Yugi Rahayu Ahadiyat

Jurnal Kultivasi

The contamination of shallots in the food chain by heavy metals such as lead (Pb) and cadmium (Cd) is caused by chemical fertilizers and pesticides. The study aimed to determine the growth and yields of shallot cultivated on soil contaminated with Pb and Cd using mycorrhiza and biochar. The study was conducted in the screen house at Jenderal Soedirman University, Faculty of Agriculture, from April to September 2020, and it was carried out using a factorial Randomized Completely Block Design that involved three replications and two factors. The first factor of mycorrhiza dosage comprised 0, 1, and 2 g/pot, and …

Conditional Cooperation With Longer Memory, Nikoleta E. Glynatsi, Ethan Akin, Martin A. Nowak, Christian Hilbe

Mathematics and Statistics Faculty Research & Creative Works

Direct reciprocity is a wide-spread mechanism for the evolution of cooperation. In repeated interactions, players can condition their behavior on previous outcomes. A well-known approach is given by reactive strategies, which respond to the coplayer's previous move. Here, we extend reactive strategies to longer memories. A reactive-n strategy takes into account the sequence of the last n moves of the coplayer. A reactive-n counting strategy responds to how often the coplayer cooperated during the last n rounds. We derive an algorithm to identify the partner strategies within these strategy sets. Partner strategies are those that ensure mutual cooperation without exploitation. …

Current Status And The Significance Of Local Wisdom Biofertilizer In Enhancing Soil Health And Crop Productivity For Sustainable Agriculture: A Systematic Literature Review, Irwandhi, Fiqriah Hanum Khumairah, Emma Trinurani Sofyan, Nadia Nuraniya Kamaluddin, Anne Nurbaity, Diyan Herdiyantoro, Tualar Simarmata

Jurnal Kultivasi

Soil fertility is recognized as a crucial factor in supporting plant growth and productivity. The utilization of biofertilizers as environmentally friendly fertilizers is aimed at enhancing soil fertility and plant productivity. This study aims to explore the potential of local material for developing local wisdom biofertilizers (LWB) for achieving sustainable agriculture. A systematic literature review was conducted using bibliometric analysis, Preferred Reporting Items for Systematic Reviews, and Meta-Analyses (PRISMA) method, employing the Scopus search engine with the keywords "local AND wisdom AND biofertilizer" OR "biofertilizer" OR "local AND microorganism" OR "soil AND health OR crop AND productivity OR sustainable agriculture". …

Increased Thermal Stability And Retained Antibacterial Properties In A Sulbactam And Amantadine Salt: Towards Effective Antibacterial-Antiviral Combination Therapies, Josephine Bicknell, Ivan Bondarenko, Alice Colatrella, Elani J. Cabrera-Vega, Jesus Daniel Loya, Delbert S. Botes, Jay L. Mellies, Gonzalo Campillo-Alvarado

Chemistry Faculty Publications and Presentations

A clinically relevant multidrug solid comprising sulbactam (β-lactamase inhibitor) and amantadine (antiviral) displays enhanced thermal stability and sustained antibacterial activity compared to starting materials.

We describe the formation of a multidrug salt comprising sulbactam (SUL, β-lactamase inhibitor) and amantadine (AMNH, antiviral). Physicochemical investigation of the SUL·AMNH salt revealed enhanced thermal stability compared to pristine starting materials. In vitro studies found that salt formation in SUL·AMNH does not disrupt antibacterial activity against model organisms Escherichia coli and Staphylococcus epidermidis. To our knowledge, we show the first β-lactamase inhibitor-antiviral salt where both components have been approved by the U.S. Food and Drug …

Na2B12Si6Se18: A Novel B12-Cluster-Containing Quaternary Selenoborate Framework Material, Gopabandhu Panigrahi, Hunter B. Tisdale, Gregory Morrison, Hans Conrad Zur Loye

Faculty Publications

We report the successful synthesis of the new quaternary, three-dimensional Na₂B₁₂Si₆Se₁₈ material using a solid-state synthesis route. This compound is characterized by a unique framework structure that features the rare icosahedral [B₁₂]¹⁰⁺ cation which is connected via Si2Se6 polyhedral units into a 3D framework structure with Na+ ions located inside the channels. The Na₂B₁₂Si₆Se₁₈ compound crystallizes in the cubic crystal system in the space group Im, with lattice parameter a = 11.91110(10) Å and unit cell volume of 1689.88(4) ų. …

Antibiotic Resistance Of Laboratory E. Coli Strains, Alexis H. Hart

Honors Projects

Antibiotic resistance is an ongoing global health crisis. The prevalence and distribution of antibiotic resistance in environmental microbial communities have become climactic areas of investigation due to their far-reaching implications for ecosystem health, human well-being, and the sustainability of antimicrobial efficacy.

Development Of A Rapid Method For Pfas Detection And Quantitation In Human Hair, Justin M. Allen

Student Theses

In recent years, per- and polyfluoroalkyl substances (PFAS) have emerged as a critical focus in environmental and public health research due to their persistent nature and widespread use in products ranging from non-stick cookware to firefighting foams. These "forever chemicals" resist degradation, posing significant ecological and human health risks. While extensive studies have explored PFAS in environmental matrices, research into their presence in human hair remains limited, with only a handful of studies addressing this biomarker's potential. This thesis aims to develop a robust analytical method for detecting PFAS in human hair, leveraging its unique properties to provide a long-term …

Methods In Environmental Studies, Erika Dunagan, Maya Mendoza, Posey Graber, Alex Cullins, Emma Mcginnis, Ally Nepomuceno, Isabella Buchan

Featured Student Work

This publication is a collection of undergraduate research conducted in the Methods in Environmental Studies course at the University of San Francisco in Fall 2024. The student-led projects explore the intersections of place, policy, ecology, and cultural identity through applied environmental research methodologies. Topics include a decolonial examination of the Forest Park Mound Group and Indigenous resilience in St. Louis; a comparative study of Navajo cosmology and ecological justice; a social and environmental impact assessment of Costa Rica’s National Decarbonization Plan; a psychogeographical analysis of Golden Gate Park and its impact on the psyche, emotions, behaviour, and health of urban …

A Summer Class Exploring Computer Science With Educators Of Deaf And Hard Of Hearing Students, Meghan L. Mcsherry, Becca A. Leininger, Maria L. Johnson, Annmarie P. Thomas, Susan Outlaw, Douglas C. Orzolek

Journal of Science Education for Students with Disabilities

The purpose of this research project was to design, deliver, and informally assess the content and methodology of an introductory course focused on the block-based coding language, Scratch, for educators of Deaf and Hard of Hearing students (N=20). Prior work by The Playful Learning Lab examined various STEM resources and their effect on student perception of STEM topics and content retention when utilized for Deaf and Hard of Hearing K-12 students. Previous research has shown that computer science and programming resources and curricula available today are not fully accessible for Deaf and Hard of Hearing K-12 students. Educators and teachers …

Spatial Ecology Of Large Bodied Ichthyofauna In The Red River Of The North Basin, William Marshall Stuart

School of Natural Resources: Dissertations, Theses, and Student Research

Understanding spatial patterns and processes is essential for designing research studies, implementing management actions, and planning restoration efforts. The Red River of the North basin spans a broad geographic area where jurisdictional oversight is divided among several entities (Manitoba, CAN; North Dakota, USA; Minnesota, USA; South Dakota, USA), creating a mosaic of regulatory and functional process zones. Understanding the spatial ecology of freshwater fishes in this disjointed landscape is essential to address diverse life history requirements and the movement constraints imposed by anthropogenic structures. Long-term acoustic telemetry revealed that large bodied ichthyofauna employ a diverse range of movement strategies (i.e., …

Spatiotemporal Patterns In Orbicella Faveolata Wound Regeneration As An Indicator Of Colony Health, Alexander G. Wheeler

All HCAS Student Capstones, Theses, and Dissertations

Anthropogenic (e.g. damage from anchors, scuba divers, tissue sampling) and natural disturbances (e.g. predation, storm damage) can result in wounding of live tissue on coral colonies. Wounding has been shown to detract from a common resource pool, increasing disease susceptibility and impairing coral growth and reproductive activity. Regeneration not only varies between species, but also between conspecifics in the same location. A colony’s capacity to regenerate tissue can be an indicator of a colony’s condition and resilience. Understanding the physiological and environmental factors that affect tissue regeneration alongside the ultimate impact of sampling (disease and predation correlations) are needed for …

The Investigation Of The Antimicrobial And Biofilm-Disrupting Properties Of Synthesized Hemibastadin Derivatives., Antonio Harvey

Longwood Senior Theses

This thesis explores the synthesis of a polyphenolic hemibastadin-1 derivative with presumed antimicrobial properties and improved biological safety. Structural modifications included replacing aromatic bromine atoms with phenolic groups and substituting the oxime linker group on the core structure for a triazole. A divergent synthetic strategy was designed with the dimeric nature of these targeted molecules in mind. Although this stepwise synthesis is not complete, the core triazole derivative was prepared with a respectable overall yield of 47% from the methyl gallate starting material. The final steps of the synthesis will require coupling of the divergent intermediates and deprotection of this …

Effect Of Polyacrylamide Gel Elasticity On Collagen Type Ii Fibril Assembly, Kathryn G. Wilcox, Stephanie Kramer, Surajit Chatterjee, Adam Linscott, Sneha Suresh, Lydia Kisley, Svetlana Morozova

Faculty Scholarship

Collagen type II fibrils provide structural integrity to the articular cartilage extracellular matrix. However, the conditions that control the fibril radial size scale, distribution, and formation inside of dense networks are not well understood. We have investigated how surrounding elastic networks affect fibril formation by observing the structure and dynamics of collagen type II in model polyacrylamide gels of varying moduli. Cryogenic transmission electron microscopy (cryo-TEM) is used to image the fibril structure and is verified qualitatively with optical microscopy of fluorescently-tagged collagen within the gels. Using fluorescence correlation spectroscopy super-resolution optical fluctuation imaging (fcsSOFI), the diffusion dynamics of the …

Rings Of Power: Controlling Sod Mimic Activity By The Addition Of Pyridine Rings Within The Pyridinophane Scaffold, Katherine J. Smith, Timothy M. Schwartz, David M. Freire, Cameron Bowers, Sarah K. Dunn, Jackson F. Bonnell, Magy A. Mekhail, Giridhar Akkaraju, Kayla N. Green

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Superoxide dismutase enzymes are a major defense against superoxide, which is a potent reactive oxygen species. Misregulation of reactive oxygen species and subsequent neuronal damage are etiological hallmarks of neurodegenerative disease. Macrocyclic small molecules have offered inroads toward functional SOD1 mimics. Herein, we report a series of five tetra-aza macrocyclic ^RPy₂N₂ ligands, varied by 4-position substitution of the pyridine ring with both electron-donating (R = OMe) and withdrawing groups (R = Cl, I, and CF₃) to offer the first comparison to well-studied ^RPyN₃ congeners and other mimics in the literature. New ligands …

Comparing Metabolism And Hypoxia Tolerance Of Native And Non-Native Florida Freshwater Fishes In Climate Change Scenarios, Benjamin A. Share

All HCAS Student Capstones, Theses, and Dissertations

As climate change brings rising water temperatures and lower dissolved oxygen (DO) concentrations to freshwater bodies, it has become increasingly important to understand how this will affect ecosystems with established non-native or invasive species. Fishes of the family Cichlidae are the most pervasive non-native fishes in the Everglades and may increase their range further north under a changing climate. To better understand potential invasibility and competition with native fishes, the metabolism and hypoxia tolerance of non-native Blue Tilapia Oreochromis aureus was compared to native Bluegill Lepomis macrochirus when acclimated across a range of seasonal and projected temperatures. Intermittent-flow respirometry was …

Alphafold2-Based Characterization Of Apo And Holo Protein Structures And Conformational Ensembles Using Randomized Alanine Sequence Scanning Adaptation: Capturing Shared Signature Dynamics And Ligand-Induced Conformational Changes, Nishank Raisinghani, Vedant Parikh, Brandon Foley, Gennady M. Verkhivker

Mathematics, Physics, and Computer Science Faculty Articles and Research

Proteins often exist in multiple conformational states, influenced by the binding of ligands or substrates. The study of these states, particularly the apo (unbound) and holo (ligand-bound) forms, is crucial for understanding protein function, dynamics, and interactions. In the current study, we use AlphaFold2, which combines randomized alanine sequence masking with shallow multiple sequence alignment subsampling to expand the conformational diversity of the predicted structural ensembles and capture conformational changes between apo and holo protein forms. Using several well-established datasets of structurally diverse apo-holo protein pairs, the proposed approach enables robust predictions of apo and holo structures and conformational ensembles, …

Nanofabrication Of Tetraphenyl Porphyrin Surface Assemblies Linked With Tin Tetrachloride: A Scanning Probe Microscopy Investigation, Quynh Do

LSU Doctoral Dissertations

Scanning probe microscopy (SPM) and colloidal lithography methods were used to study the covalent coupling of porphyrins to surfaces. In this dissertation, experimental methods for SPM operation, techniques, and applications are described. Measurement of tip-sample interactions between a sharp tip and surface is translated into digital image data maps with x-, y-, and z-data. Colloidal lithography can be used to fabricate test platforms for AFM studies. The periodicity and arrangement of the designed nanostructures is determined by the size of the colloidal particles used for surface masks. Data processing is required to obtain images and topography information from raw AFM …

D101n: A Unique And Ill-Understood Familial Als-Related Sod1 Mutant, Analisa Lott

Honors Program Theses and Research Projects

Background: Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease, with 90% of documented cases considered sporadic and about 10% showing a hereditary link; such cases are deemed as familial ALS (fALS). Superoxide dismutase (SOD), a copper-zinc binding enzyme that protects cells from damaging free radicals, has been linked to fALS with certain toxic gain of function mutations, such as the D101N mutant. The human SOD1 D101N mutant has been shown to be associated with rapidly progressing neurodegeneration yet is less prone to aggregation than similar mutants, but its deviation from wild-type (WT) SOD1 remains misunderstood.

Objective: Although the D101N …

Reaction Of A Chiral Platinum Triamine Compound With Key Amino Acid And Guanine Analog, Onu Emmanuel Chukwu

Masters Theses & Specialist Projects

Platinum compounds can exhibit cytotoxic activity through reaction with DNA; however, interaction with proteins and DNA bases, especially with methionine residues and Guanine analogs, is another common biological reaction. Our lab has synthesized Chloro[2-(4-Methyl-1,4- diazepan-1-yl) ethanamine]platinum(II) chloride ([Pt(L)Cl]Cl), which has a tridentate binding mode for the amine ligand. This study focused on the reaction of the chiral platinum triamine with key amino acids (methionine and 2-hydroxybutyric acid) and guanine analogs under different pH and temperature conditions. The mass spectrometry of N-AcMet Interaction with [Pt(L)Cl]+ showed a m/z of 542 and 579 for reactions at pH 4. The m/z of 542 …

(R2100) Optimality Conditions Of A Topsis Optimization Model And Its Application On Interval-Valued Data, Sudipta Roy, Sandip Chatterjee

Applications and Applied Mathematics: An International Journal (AAM)

The Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) is widely used in the field of multi-criteria decision analysis. Despite its popularity and widespread application, little attention has been given to the mathematical foundation that underlies the TOPSIS algorithm. The existing literature on this subject is far from comprehensive, leaving many aspects of the algorithm unexplored. This paper aims to address this gap in the literature by delving into the optimization problem associated with TOPSIS. Unlike traditional interval analysis theory, which only covers a limited scope, our approach extends to a broader range of scenarios and offers …

(R2111) Effect Of Stenotic-Aneurysmal Arterial Regime On Unsteady Magnetohydrodynamic Non-Newtonian Blood Flow With Heat Radiation, Babatunde A. Joseph, Dada M. Sunday, Bello A.J. Funsho, Akeem B. Disu, Alamu-Awoniran F., Danas James Y.

Applications and Applied Mathematics: An International Journal (AAM)

The study aims to investigate the effect of magneto-hydrodynamic on a non-Newtonian unsteady blood flow with internal heat energy in the presence of blood ironic properties characterized by stenosis. The formulated mathematical equations resulted in differential forms and were solved analytically by Differential Transform Method. The obtained solutions were displayed by graphs showing different flow physiognomies like blood velocity, temperature profile, Nusselt number, wall shear stress and stream function.

The results indicated that velocity profile increases as magnetic field, Darcy number and aneurysmal artery rise, while it decreases as heat radiation, Reynold number, and Casson parameter speedup. The temperature profile …

Northern Great Plains Native Seed Strategy, Lora Perkins, Amy Symstad, Jennifer Zavaleta-Cheek, Emily Rohrer, Krista Ehlert

Native Plant Initiative Newsletters and Reports

Developed by the Northern Great Plains Native Seed Partnership

Photogeneration, Characterization, And Kinetic Study Of A New Phthalocyanine Species, Sobenna Onyeso

Masters Theses & Specialist Projects

In the search for green chemistry, the development of synthetic metal complexes that model enzyme function has been extensively studied. Phthalocyanine metal complexes, closely related to these heme-containing macrocycles, have gained continued interest due to their ease of direct synthesis, efficient redox, and optical properties. Despite the significant progress in phthalocyanine metal complexes, much more work needs to be done in the characterization and identification of their metal-oxo species, as well as mechanistic insights into their catalytic oxidations. To date, the reactivity of metal-oxo species on phthalocyanine platforms has not been probed.

In this study, metal phthalocyanine complexes have been …

The Impacts Of Seasonality And Nutrient Loading On Microcystis Bloom Development In Wall Pond, Alyssa Antolak

Bridges: A Journal of Student Research

The harmful cyanobacteria Microcystis dominates eutrophic freshwater systems globally. Eutrophication leading to nitrogen and phosphorus loading into aquatic systems is increasing bloom propagation and shifting diatom/dinoflagellate dominated systems to cyanobacteria dominated systems. Understanding seasonal variability and environmental parameters combined with nutrient loading will allow for better understanding of what factors are influencing Microcystis blooms. Biweekly plankton samples and environmental parameters were collected from Wall Pond on campus from spring 2022-spring 2023. Results show that yearly plankton samples shifted from Microcystis dominated in the early summer to diatom dominated in the late summer-early fall, then back to Microcystis dominated in late …

Are Rising Seas Pushing Ghost Crabs Out Of Their Comfort Zone?, Finn Gillette

Bridges: A Journal of Student Research

Ghost crabs (Ocypode quadrata) can be found on sandy beaches bordering the western Atlantic Ocean. These semiterrestrial crustaceans are often found between the swash zone and the dunes on beaches. Dunes are critical refuges for ghost crabs during storms and extreme tide events. This makes them a useful indicator species for monitoring the effects of global warming-induced sea level rise on beach biota, as their distribution patterns among beach zones may correlate with shifts found in other species. Beach surveys conducted from 2015 onward assessed the population density of ghost crabs on beaches of Horry and Georgetown counties in South …

Establishment Of Structure-Property-Processing Relationships For Design Of Sprayable Hydrogels And Amyloid/Peo Electrospun Composites, Xianjun Wang

Dissertations

The focus of this dissertation is the design, synthesis, characterization, and prototyping of bio-inspired materials to understand the role of structure, intermolecular interactions, and processing technique on the self-assembly, bioactive properties, and mechanical properties of the biomaterials. This work is divided into three research areas: 1) sprayable and adhesive glycopolymer based hydrogels; 2) decapeptide-based composite nanofiber mats; and 3) prototyping sutures and meshes via electrospinning. The established structure-property-processing relationships provide a foundation for designing biomaterials in the future.

The first chapter provides an introductory overview of the requirements necessary for the development of hydrogels, glycopolymers, and peptides, including relevant processing …

Neutrosophic Cox Proportional Hazards Model For Robust Variable Selection In Survival Analysis, Ibrahim Yasser, Aya A. Abd El-Khalek, A. A. Salama, Doaa A. Abdo

Neutrosophic Systems with Applications

This paper introduces a novel approach for variable selection in survival analysis by integrating neutrosophic logic into the Cox Proportional Hazards (Cox PH) model to address the limitations of recent studies related to high dimensionality. Neutrosophic logic, is a mathematical framework that allows for uncertainty, indeterminacy, and inconsistency, and particularly well suited for handling the complexity and often-ambiguous nature of biological data. By incorporating neutrosophic sets into the Cox PH model, we aim to enhance model robustness, improve variable selection, and address the curse of dimensionality. We compare the performance of the neutrosophic-enhanced Cox PH model with traditional variable selection …

(R2095) On Discrete Hypoexponential Distribution And Integer-Valued Autoregressive Process, K. Krishnakumari, Dais George

Applications and Applied Mathematics: An International Journal (AAM)

Discrete distributions provide a substantive contribution in modeling real world frame work. Though a lot of discrete distributions are available in literature, they are inappropriate to model many practical situations. The conventional discrete distributions like geometric, Negative Binomial and Poisson have limited applications in modeling count and lifetime data. This paper introduces a new two parameter discrete distribution namely, discrete hypoexponential distribution by discretizing the well known hypoexponential distribution. Various distributional and structural properties of the proposed distribution are studied. We introduce a first order auto regressive process with the newly proposed distribution as marginal and study the properties. Depending …

(R2108) Global Asymptotic Stability Analysis Of Discrete Time Population Model With Allee Effect Through Lyapunov Function, Govind Jha, Neeraj Kumar, Sarita Jha

Applications and Applied Mathematics: An International Journal (AAM)

This study explores the idea of stability analysis by using Lyapunov functions in discrete time population models; this work focuses on the nth generation. Further, this investigation aims to extend global stability concepts to discrete-time models and considers the influence of the Allee effect on population dynamics. Mathematical formulations and specific modelling approaches are utilized to investigate the behavior of the population system. The results reveal a larger range of stability in comparison to previous findings, emphasizing the effectiveness of the Lyapunov function approach. Specifically highlighted here are the extension of global stability concepts to the nth generation providing insights …

(R2099) Boundedness And Square Integrability In Neutral Differential Equations With Delay And Exponential Stability In Nonlinear Differential Equations Of Third-Order, Fatima Abdellaoui, Mebrouk Rahmane

Applications and Applied Mathematics: An International Journal (AAM)

The Lyapunov second method is an eigenvalue-based technique which consist of finding a Lyapunov function candidate for studying the stability of dynamical systems which is hard to deal with especially in most of nonlinear cases. Studying the stability and some of other qualitative behaviors based on the Lyapunov second method is research topic of actuality because of the wide range of applications of the differential equations. Many authors in the literature have used the second method of Lyapunov in the study of some qualitative behaviors from which the stability, the boundedness and the square integrability of solutions for various kinds …