Digital Commons Network^™

Untangling The Classification Of Surfaces: An Accessibility-Centered Perspective On Topology, Charlotte N. Richards

Pitzer Senior Theses

Mathematics has clear benefits in education, from preparing students for future careers to teaching them how to problem-solve. While mathematics achievement has been falling in recent decades, students claim that the problem is not the mathematics itself, but the ‘boring’ classroom material that feels removed from real life. More advanced mathematics topics, such as topology, could offer a solution, as their applications lie in countless fields. However, topology has been restricted to upper-level mathematics, disregarding the potential benefits of making this material broadly reachable for a junior high-school audience. In this paper, we analyze five different proofs of the theorem …

Urban Heterogeneity Drives Dissolved Organic Matter Sources, Transport, And Transformation From Local To Macro Scales, Rebecca L. Hale, Kristina G. Hopkins, Krista A. Capps, John S. Kominoski, Jennifer L. Morse, Allison H. Roy, Shuo Chen, Annika Quick, Andrew J. Blinn, Liz Ortiz Muñoz, Gwendolynn Folk

Environmental Science and Management Faculty Publications and Presentations

Urbanization reshapes dissolved organic matter (DOM) sources, transport, and transformations through changes in vegetation, hydrology, and management of waste and water. Yet the impacts of urbanization on DOM are variable within and among cities. Predicting heterogeneous responses to urbanization is challenged by diverse human activities and underlying biophysical variation along stream networks. Using data from the 486 largest urban areas in the continental United States and seven focal cities, we identified macro and local scale urban gradients in social, built, and biophysical factors that are expected to shape DOM. We used these gradients and the literature to develop hypotheses about …

Restoring Rattlesnake Creek: Using Citizen Science To Assess The Ecological And Morphological Impacts Of Dam Removal In Western Montana, Bethany Blakey

Undergraduate Theses, Professional Papers, and Capstone Artifacts

As dam removals increase in frequency across the U.S., most research has focused on the impact of larger dam removals, despite the removal of small dams being much more common. Given the hundreds of small dams in Montana, this research uses citizen science data collected over eight years spanning before and after a 2020 small dam removal in Rattlesnake Creek, Montana, to investigate impact on stream ecology and morphology. We analyzed pebble count grain size distributions and aquatic macroinvertebrate biotic indices from 2017 to 2024 to assess changes in sediment transport and macroinvertebrate population as well as evaluate the efficacy …

Neutrosophic Twofold Superhyperalgebra And Anti Superhyperalgebra, Takaaki Fujita, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

Neutrosophic Sets are conceptual frameworks designed to address uncertainty. A Neutrosophic TwoFold Algebra is a hybrid algebraic structure defined over a neutrosophic set, combining classical algebraic operations with neutrosophic components. Concepts such as Hyperalgebra and Superhyperalgebra extend classical Algebra using Power Sets and 𝑛-th powersets. Additionally, structures such as NeutroAlgebra and AntiAlgebra have been defined in recent y ears. This paper explores several related concepts, including TwoFold SuperhyperAlgebra and Anti SuperhyperAlgebra.

Automatic Identification And Visualization Of Reaction Mechanisms Contained Within Direct Dynamics Simulations, Trent Kobulnicky, Emmanuel Boafo, George L. Barnes

Faculty Publications – Chemistry

Direct dynamics simulations are employed in many areas of chemistry and biochemistry. When paired with an appropriate underlying ab initio, semiempirical, or DFT-based potential energy surface and proper sampling of initial conditions, direct dynamics simulations provide an atomic-level view of the reaction dynamics within the system of interest, yielding considerable fundamental insights. Moreover, when a sufficient number of simulations are conducted, they provide a wealth of information regarding the overall trends in reactivity. However, they also generate large data sets that often require significant manual interpretation through inspection or developing case-specific analysis techniques. Here, we present an analysis method …

Oriented Surface Immobilization Of Antibodies Using Enzyme-Mediated Site-Specific Biotinylation For Enhanced Antigen-Binding Capacity, Emily Beitello, Kwame Osei, Trent Kobulnicky, Faith Breausche, Jon A. Friesen, Jeremy D. Driskell

Faculty Publications – Chemistry

The effectiveness of surface-immobilized antibodies is often diminished by improper antibody orientation and limited stability, impeding the analytical performance of biosensors. Here, we report a novel enzyme-mediated strategy to biotinylate the Fc region of an anti-horseradish peroxidase (anti-HRP) antibody with site-specificity that enables oriented immobilization on a streptavidin-functionalized surface. Microbial transglutaminase (mTG) catalyzes the covalent coupling between the amine functional group on a biotin analogue (NH₂-PEG₄-biotin) and the side chain of a privileged glutamine residue (Q295) located on the heavy chain Fc region of IgG antibodies. For comparison, an anti-HRP antibody was biotinylated using an amine-reactive …

Synthesis Of Alkyl Substituted Carbatripyrrins And Their Application To The Preparation Of Carbaporphyrins And Oxacarbaporphyrins, Ian A. Mclauchlan, Bethany K.X. Overbey, Tyler J. Smolczyk, John J. Woods, Timothy D. Lash

Faculty Publications – Chemistry

Unsubstituted carbatripyrrins have previously been shown to be useful intermediates in the synthesis of benzocarbaporphyrins and related core-modified analogues. However, the absence of substituents often resulted in the formation of poorly soluble products. In this study, four examples alkyl substituted carbatripyrrins were constructed by base-catalyzed condensation of dihydrofulvenes with pyrrole aldehydes. Further reaction with a pyrrole dialdehyde in the presence of trifluoroacetic acid afforded a series of carbaporphyrins, while reactions with 2,5-furandicarboxaldehyde generated oxacarbaporphyrins. These results demonstrate that alkyl substituted carbatripyrrins are promising precursors to new carbaporphyrinoid structures.

Synthesis And Characterization Of Free Radical Scavenging Dendrimer Nanogels Via Cross-Linking Reaction-Enabled Flash Nanoprecipitation, Lin Qi, Da Huang, Huari Kou, Anna Chernatynskaya, Nuran Ercal, Hu Yang

Chemistry Faculty Research & Creative Works

This work reports the development and evaluation of dendrimer-based nanogels based on Poly amidoamine (PAMAM) dendrimer generation 5, engineered to act as a carrier with reactive oxygen species (ROS)-scavenging capabilities. We developed a cross-linking reaction-enabled flash nanoprecipitation method in which the cross-linking reaction occurs during the flash nanoprecipitation process to form a cross-linked nanostructure. Using this approach, an N-hydroxy succinimide (NHS)-functionalized ROS-responsive thioketal cross-linker (TK-NHS) was synthesized and utilized to cross-link DAB-core PAMAM dendrimer G5, resulting in the formation of G5-TK nanogels. The resulting nanogels were characterized using dynamic light scattering and transmission electron microscopy, and their cytocompatibility, irritancy, cellular …

Scalable Fabrication Of High-Payload Dendrimer-Based Nanoparticles For Targeted Atherosclerosis Therapy, Huari Kou, Lin Qi, Da Huang, Jiandong Wu, Honglan Shi, Hu Yang

Chemistry Faculty Research & Creative Works

Nanoparticle-based therapeutics hold promise for the treatment of atherosclerosis, but challenges such as low drug-loading capacity and a lack of scalable, controllable production hinder their clinical translation. Flash nanoprecipitation, a continuous synthesis method, offers a potential solution for scalable and reproducible nanoparticle production. In this study, we employed a custom-designed multi-inlet vortex mixer to perform cross-linking reaction-enabled flash nanoprecipitation, facilitating controlled and scalable synthesis of cross-linked Poly amidoamine (PAMAM) dendrimer nanoparticles. Notably, this approach allows simultaneous nanoparticle cross-linking and drug loading in a single step. The mannose moiety enabled specific targeting of macrophages via mannose receptors, enhancing the localization of …

Analyzing Factors Influencing Employee Turnover In Tech Companies: A Predictive Modeling Approach, Shinjon Ghosh

Theses and Dissertations

Employee turnover poses substantial challenges for technology firms, and understanding its key drivers through predictive modeling is essential for developing effective retention strategies. This study investigates factors influencing employee turnover in technology companies by implementing a predictive modeling approach on the IBM HR Analytics Employee Attrition dataset. The research aims were identifying key factors contributing to employee attrition, developing predictive models to forecast turnover risk, and analyzing interactions among significant predictors. By examining a range of features, the results highlight significant variables (Over Time, Monthly Income, Marital Status, etc.) of attrition and offer actionable insights for developing targeted employee retention …

Exploring Nitrate Reduction In A Saturated Riparian Buffer Through A Three-Dimensional Reactive Contaminant Transport Model In An Agricultural Area, Mcclean County Central Illinois, Franklin O. Ijigade

Theses and Dissertations

Saturated Riparian Buffers (SRBs) are engineered systems designed to remove nitrate and other pollutants from subsurface agricultural drainage water before it reaches a stream. This study utilizes a high-resolution coupled flow and reactive transport model to explore nitrate reduction and transformation in an SRB in glacial sediment. The influence of material heterogeneity on nitrate reduction and the effectiveness of the SRB was investigated. The study was conducted in an SRB located next to and receiving tile drainage water that ultimately drains into a 3^rd order stream (T3 stream) in central Illinois, USA. A three-dimensional steady groundwater flow model was …

Application Of Floating Wetlands To Improve Urban Stream Quality, Daniel Chukwunonso Chukwudi

Theses and Dissertations

Urban streams, impacted by urbanization, often exhibit degraded water quality due to elevated nutrient levels, a phenomenon known as urban stream syndrome. This study evaluates the effectiveness of a floating wetland (FW) system in reducing nitrate as nitrogen (NO₃-N) and phosphate (PO₄³⁻) concentrations in a side canal of the Chicago River’s North Branch, adjacent to Goose Island, Chicago, IL, from 2018 to 2023. Using a five-year dataset, including new sampling from May to December 2023, the research addresses two questions: (1) Do FWs lower NO₃-N and PO₄³⁻ concentrations in urban streams? and (2) Do FWs exhibit seasonal differences in nutrient …

A Systematic Review And Taxonomy For Privacy Breach Classification: Trends, Gaps, And Future Directions, Clint Fuchs, John Hastings

Research & Publications

In response to the rising frequency and complexity of data breaches and evolving global privacy regulations, this study presents a comprehensive examination of academic literature on the classification of privacy breaches and violations between 2010-2024. Through a systematic literature review, a corpus of screened studies was assembled and analyzed to identify primary research themes, emerging trends, and gaps in the field. A novel taxonomy is introduced to guide efforts by categorizing research efforts into seven domains: breach classification, report classification, breach detection, threat detection, breach prediction, risk analysis, and threat classification. An analysis reveals that breach classification and detection dominate …

The Road Less Traveled: A Pathway Leading To Research At A Primarily Undergraduate Institution, Timothy D. Lash

Faculty Publications – Chemistry

Scholarly activities in primarily undergraduate institutions involve very different challenges from those in major research universities. In this essay, the author discusses how he initiated a research program involving undergraduates at Illinois State University following a number of missteps and false starts. Although undergraduate researchers have much to learn, and the levels of commitment vary considerably, they can nevertheless often make important contributions.

Private Property Vs. Public Access: Socio-Engineering Framework For Managing Non-Meandering Waters In South Dakota’S Prairie Pothole Region, Lydia Loken, Sushant Mehan

The Journal of Undergraduate Research

This study addresses the growing importance of balancing private ownership and public interest of Non-Meandering Waters (NMWs) overlaying private property in the South Dakota Prairie Pothole Region (PPR) through both a legal and socio-engineering lens. This study aims to develop an integrated management framework for Non-Meandering Waters in the South Dakota Prairie Pothole Region that combines water allocation principles, the Public Trust Doctrine, and water quality objectives to guide policy decisions, ensuring equitable access, long-term sustainability, and a balanced approach to both public and private interests. Data collection from October 2024 through February 2025 and included a literature review of …

Metabarcoding-Biomass Relationships And Internal Standards For Quantitative Dna Metabarcoding, Frances Webber

Open Access Master's Theses

DNA metabarcoding has been widely adopted due to its power in investigating the composition of protistan communities, accurately identifying even small and cryptic taxa. However, the compositional nature of DNA metabarcoding results, and the distortion of natural abundances due to variation of the often-used 18S rRNA gene copy number over several orders of magnitude, renders these results semi-quantitative at best, limiting the application of DNA metabarcoding to ecological study. Here, we constructed mock communities from uni-algal cultures of taxonomically diverse phytoplankton and conducted metabarcoding using multiple primer sets and both DNA and cDNA as PCR templates. For each culture, chlorophyll …

Predicting Evapotranspiration, Quick Flow, And Recharge In The Contiguous United States Through 2100, Paige Aldenberg

Open Access Master's Theses

Groundwater pumping has more than doubled since 1950 across the United States and now accounts for more than 50% of water use in much of the country. These high pumping rates have exceeded recharge in many aquifers, especially in the dry Western United States. As a result, water levels are declining, increasing water scarcity for humans, and causing various adverse ecosystem impacts. So, predictions of future groundwater recharge rates, especially in the face of changing climates, are necessary for informing future water management practices. While historical groundwater recharge rates have been estimated across broad geographic regions, high-resolution predictions of future …

Field Performance Evaluation Of Selectively Bred Eastern Oyster Lines In New Jersey And Rhode Island, Seraphina Satkowski

Open Access Master's Theses

Eastern oyster aquaculture has increased steadily over the last three decades, but the industry has yet to achieve its full potential. In the Northeast USA, production is limited in part by a lack of high performing stocks suited to the geographically broad and heterogenous growing environments. For this study, hatchery lines from Maine, New York, and New Jersey as well as crosses between each hatchery line and the selectively bred Northeast high survival (NEHÒ) line, were deployed at oyster farms in Rhode Island and New Jersey for performance evaluation. Replicate bags of each line were stocked and maintained according to …

Geochemical And Sedimentological Signals Of Bottom Water Oxygen Dynamics From Lake Tanganyika (Zambia), Njahi Mwangala

Theses and Dissertations--Earth and Environmental Sciences

Lake Tanganyika is a large, ancient freshwater body with exceptional biodiversity that is located in the East African Rift System. Lake Tanganyika’s size and longevity make its sedimentary record useful for understanding environmental changes that cross spatial and temporal boundaries. Lake Tanganyika is known to be susceptible to global warming given its tropical location. Over 12 million people living within Lake Tanganyika’s watershed rely on fishing for their income and nutrition. Changes to limnological function driven by climate could therefore have serious implications for human health and biodiversity conservation. This study focuses on using geochemical properties of modern lake bottom …

Late Holocene Paleolimnology Of Lake Tanganyika (East Africa), Leandro Domingos Luz

Theses and Dissertations--Earth and Environmental Sciences

Understanding the long-term responses of ecosystems to climate variability is crucial for predicting and mitigating future changes in the Afrotropics, a region where a significant portion of the population is highly vulnerable to extreme climatic events. Lake Tanganyika, the largest rift lake in East Africa, offers a unique sedimentary archive that can be used to investigate the limnological changes, hydroclimatic shifts, and vegetation dynamics across various timescales. A multi-proxy approach was employed to assess the landscape responses to hydroclimatic fluctuations in the Late Holocene, integrating paleoenvironmental records from radiocarbon-dated sediment cores. This approach involved sedimentology, mineralogy, geochemistry, phytolith analysis, and …

Multi-Scale Analysis Of Karst Aquifer Vulnerability To Climate Change And Contamination Processes, Shishir Sarker

Theses and Dissertations--Earth and Environmental Sciences

Karst aquifers represent some of the world’s most productive yet vulnerable groundwater systems, supplying freshwater to approximately 10% of the global population across 15% of Earth’s ice-free land surface. Their distinctive hydrological characteristics— including rapid recharge, preferential flow paths, and limited natural filtration— create unique vulnerabilities to both climate variability and contamination that pose significant challenges for sustainable water resource management. This dissertation presents a comprehensive multi-scale analysis of karst aquifer vulnerability through three interconnected studies that examine climate change impacts, microbial contamination dynamics, and contaminant transport processes across diverse geographic and hydrogeologic settings.

Chapter two investigates climate change impacts …

Understanding The Impact Of The Medicaid Expansion On Hospital Length Of Stay And Emergency Department Use In Kentucky, Cameron Bushling

Theses and Dissertations--Epidemiology and Biostatistics

Three related analyses were performed to try to understand the immediate effects of Medicaid expansion on hospital systems in Kentucky. Medicaid expansion led to a large, sudden increase in the number of individuals eligible for various health care needs. This sudden increase in demand for health services lead to initial hypotheses regarding hospitals’ ability to handle this demand. The first analysis examined hospital average length of stay (LOS) using a linear mixed-effects model. Length of stay was modeled longitudinally between 2013 and 2015 to determine if significant changes in the slope of LOS could be detected after expansion (2014). Separate …

Iere Annual Report 2025, Erin Largo-Wight, Heather Barnes Truelove, Kelly Rhoden, Nicole Lowe, Ruby Cox

Annual Reports

2025 Annual Report of the Institute for Environmental Research and Education

Fire And Mammal Herbivory On Arthropods In The Protected Savannas: A Systematic Review, Ludzula Mukwevho, Mduduzi Ndlovu, Frank Chidawanyika

All Peer-Reviewed Publications

Protected areas in the savannas are key global reserves for biological diversity, including arthropods. Fire and mammal herbivory disrupts the diversity of biological organisms that alternately affects the functioning of the ecosystem. The study presents a global synthesis review of arthropod responses to varying intensities of fires and mammal herbivory in the protected savannas. We hypothesise that the intensity of predetermined fires and mammal herbivory has cascading impacts on abundance, species richness and diversity of terrestrial arthropods in the protected savannas. A minimum selection criteria was used to collate relevant literature from electronic databases of previous studies performed in the …

Morphometric Characterization Of Invasive Diaphorina Citri Infesting Citrus And Orange Jasmine In Ghana, Kodwo Dadzie Ninsin, Maxwell Kelvin Billah, Bernard Agyeman Boateng, Jonathan Osei-Owusu, Fred Kormla Ablormeti, Samuel Opuni-Basoa, Aboagye Kwarteng Dofuor, George Edusei, Steve B.S. Baleba, Owusu Fordjour Aidoo

All Peer-Reviewed Publications

Morphometric analysis plays a crucial role in the accurate identification and classification of insect pests, which is essential for implementing effective management strategies. The Asian citrus psyllid (Diaphorina citri Kuwayama; Hemiptera: Liviidae), an invasive species and a known vector of ‘Candidatus Liberibacter asiaticus’ and ‘Ca. Liberibacter americanus,’ the bacterial pathogens associated with Huanglongbing (HLB), has recently emerged as a pest of concern in Ghana. Despite its significance, little is known about the biological traits of field populations in the region. In this study, we examined morphometric variation in D. citri populations infesting citrus and orange jasmine (Murraya paniculata) across different …

Purification Of Recombinant His6-Gfp-Preptin Fusion Protiens, Apoorva Kollaram

Theses and Dissertations

Preptin, a 34-amino-acid peptide derived from proinsulin-like growth factor II, has emerged as a promising therapeutic candidate for both Type 2 diabetes mellitus and osteoporosis. Its dual functionality—stimulating insulin secretion without inducing hypoglycemia and promoting osteoblast proliferation—positions it as a unique alternative to traditional sulfonylureas and osteogenic agents. In this study, we developed a purification protocol for green fluorescent-preptin fusion proteins. These fusion proteins will be used to investigate the functional significance of residues Pro17, Val18, Gly19, Trp27, Lys28, and Gln29 in rat preptin, which shares high sequence similarity with the human form. Site-directed mutagenesis was performed using NEB Q5 …

An Analysis Of Coal Ash Pollution In The State Of Georgia, Mick W. Etchison

Theses and Dissertations

This social science paper will explore the factors contributing to the prevalence of coal ash in specific regions of Georgia and its impact on local ecosystems and human health. It provides an analysis of the current environmental and political issues surrounding the containment and spread of coal ash throughout the State. Coal ash is primarily found in the central, southwestern, and northeastern regions where coal-fired power plants and coal ash storage sites are located. The paper will then discuss the political, economic, and legal reasons behind the lack of effective regulation and mitigation of coal ash spread. Coal ash illustrates …

Students’ Perceptions Of Self And Peers Predict Self-Reports Of Cheating, Amber M. Henslee, Luke Settles, Sara E. Johnson, Gayla R. Olbricht

Psychological Science Faculty Research & Creative Works

Academic dishonesty and how to address it are common concerns across higher education disciplines, but engineering students admit to higher rates of academic dishonesty than other students. However, first-year students may be particularly receptive to prevention efforts. Considering self-perception, social norming, and behavioral choice theories, we hypothesized that 1.) Students who perceived themself as ethical and more knowledgeable of the consequences for misconduct would be less likely to self-report cheating and 2.) Students who perceived cheating and plagiarism to be common would be more likely to self-report cheating. For this study, freshmen engineering students (N=703) reported their self-perception, perception of …

An Understanding Of The Feeding Ecology Of Teleoceras Fossiger And Teleoceras Aepysoma Using Dental Microwear And Mesowear Analysis, Gabriel S. Goncalves

Master's Theses or Doctor of Nursing Practice

Teleoceras is a genus of rhinocerotids that belongs to the Tribe Teleoceratines and was widespread across North America from the late Early Miocene into the Early Pliocene. This genus was very successful, spreading across the continental United States from Florida and Tennessee to California and Washington state down to central Mexico and Honduras. Teleoceras is characterized by having a large, rounded chest cavity and short limbs with relatively high crowned teeth and lower incisors modified into tusk-like teeth. Initial ecological comparisons were made to the modern hippopotamus based on proportions of the chest cavity and its hypsodont dentition. Stable carbon …

Geochemical Assessment Of Sediment Flux In A Sediment Core From A Tidal Flat In A Tropical Estuary, Olumide Ajulo

Master's Theses or Doctor of Nursing Practice

Sediment flux in estuaries is influenced by both natural processes and anthropogenic activities. Understanding the historical and current trends in sediment flux inputs and geochemical composition are essential for evaluating the estuary’s response to natural and human-induced changes and for developing effective environmental management strategies. The tropical Wouri Estuary in Cameroon receives water and sediment inputs from three main rivers draining urban, industrial, and agricultural areas, as well as different rock terrains. The complex inputs into the estuary can significantly affect sediment flux, consequently impacting the ecosystem. Thereby making an understanding of the temporal variations in sediment inputs in the …