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The Reproducibility Crisis In Scientific Research, Sarah Eline

Senior Honors Projects, 2010-2019

Following the push for evidence based practice, came a huge proliferation of research journals and journal articles. With this increase in quantity came an increased concern about the quality of these articles being published, which led to a multifield investigation regarding the reproducibility of scientific research. With studies in the fields of psychology and biomedicine only reaching approximately a 30% reproducibility rate, a conversation has been sparked that spans across every field of research. Upon further investigation, various causes for this reproducibility crisis have surfaced which include, lack of data sharing/ transparency, statistical errors, funding corruption, and the culture surrounding …

Nurse-Led Design And Development Of An Expert System For Pressure Ulcer Management, Débora Abranches, Dympna O'Sullivan, Jon Bird

Conference papers

The use of Clinical Practice Guidelines (CPGs) is known to enable better care outcomes by promoting a consistent way of treating patients. This paper describes a user-centered design approach involving nurses, to develop a prototype expert system for modelling CPGs for Pressure Ulcer management. The system was developed using Visirule, a software tool that uses a graphical approach to modeling knowledge. The system was evaluated by 5 staff nurses and compared nurses’ time and accuracy to assess a wound using CPGs accessed via the Intranet of an NHS Trust and the expert system. A post task qualitative evaluation revealed that …

Tidying And Analysis Of The 2014 Texas English Ii End-Of-Course Exam, David Churchman, Abigail Morton Garland

SMU Data Science Review

The state of Texas requires all public high school students to take End of Course (EOC) exams. The results of these exams are made nominally public, but in a shape and format that precludes ready analysis. To the extent possible, principles of tidy data will be applied to clean and analyze the publicly released data file for the 2014 English II EOC exam, providing insights into the EOC program and a case for better public data from the Texas Education Administration (TEA).

Elemental Analysis Of Edible Clay From The Copperbelt Province Of Zambia, Amelia M. Craze, Mina L. Brandon

Venture: The University of Mississippi Undergraduate Research Journal

Trace elements in three edible clay samples from an open-air market in Kitwe, Zambia were analyzed for heavy metals using a scanning electron microscope coupled with an energy-dispersive spectrometer. The ingestion of clays has been observed throughout history but persists in many rural countries that lack sufficient access to proper medical care. In many African countries, women have been observed eating clay during pregnancy to reduce nausea or meet their recommended intake of iron. Similar studies identified harmful heavy metals in the makeup of the edible clays, however, the results of this analysis elemental analysis coupled with the SEM for …

Factors Influencing The Spatial Distribution Of Southern Rust In Corn, Justin Bailey

Graduate Theses and Dissertations

Southern rust caused by the fungus Puccinia polysora (Underwood) is the most economically important foliar disease in corn (Zea mays) (Linnaeus) (Cyperales: Poaceae)) for Arkansas. The objective of this work was to determine distribution of southern rust in corn and to determine factors that may control its distribution.

During the 2017 and 2018 season, seven corn fields in Arkansas were rated for southern rust. After disease confirmation, fields were marked with GPS sample point locations in a grid pattern across the entire field. Ratings for disease severity were taken below, at, and above the ear leaf at each point every …

Community Ecology And Population Dynamics Of The Nearshore Marine Fauna In The Middle Atlantic Bight (Usa), Juan Carlos Levesque

Earth & Environmental Sciences Dissertations - Archive

Natural resources are among the most valuable commodities on earth. Some natural resources (air, land, and water) are essential for human survival and many often constitute a large percentage of local, regional, and national economies, such as marine resources. Worldwide, marine resources have shaped culture, society, and local, regional, and global economies. Oceanic environmental conditions influence, shape, and control the geographical range, spatial distribution, abundance, and size composition of marine fauna. Thus, marine communities are vulnerable to major changes in the environmental conditions and disturbance (short and long-term), but the response and severity depends on various biological or ecological factors, …

Observations On The Magnetic Iron Oxide Content Of Particulate Matter In The Sahel, Kimberly Belle Tidd

Earth & Environmental Sciences Theses - Archive

Atmospheric dust influences many processes throughout the biosphere, hydrosphere, and atmosphere, most notably the climate, marine productivity, and human health. Recognizing the physicochemical characteristics of dust particulates will assist with monitoring the changes brought on by dust storms, as well as changes that may occur if dust subsides. Munsell soil color analysis was used to identify the degree of weathering at sample collection sites from the Sahel, a climate-sensitive region of North Africa. Scanning electron microscopy and energy dispersive x-ray spectroscopy were used to obtain the size, shape, and elemental makeup of individual magnetic metal particulates. Samples examined were collected …

Leveraging Environmental Research And Observation Networks To Advance Soil Carbon Science, Alejandro N. Flores

Geosciences Faculty Publications and Presentations

Soil organic matter (SOM) is a critical ecosystem variable regulated by interacting physical, chemical, and biological processes. Collaborative efforts to integrate perspectives, data, and models from interdisciplinary research and observation networks can significantly advance predictive understanding of SOM. We outline how integrating three networks—the Long‐Term Ecological Research with a focus on ecological dynamics, the Critical Zone Observatories with strengths in landscape/geologic context, and the National Ecological Observatory Network with standardized multiscale measurements—can advance SOM knowledge. This integration requires improved data dissemination and sharing, coordinated data collection activities, and enhanced collaboration between empiricists and modelers within and across networks.

Undergraduate Research Experiences Reports On Acne Treatment, Heavy Metal In Water, And Measurement Of The Heat Reaction Of Isosorbide Methacrylate, Jaida Lewis

Honor’s College Freeman Research Journal

This thesis reports on three significant science projects I have done during my undergraduate years. The first part is on the effect of Benzoyl Peroxide and Salicylic, two active ingredients in face wash for acne control, on MCF-7, epithelial cells. My assays suggested that salicylic acid lowered the viability of the MCF-7 cells, meaning it is more likely to decrease the viability of acne cells, while benzoyl peroxide did not seem to have any effect at all, meaning it is safer to use on the skin. My second research involved measurement of heavy metals, such as aluminum, nickel, cadmium, lead, …

Hydroponics: Effect Of Ph On Different Cucumber Varieties, Mikaela Krumrei

Department of Environmental Studies: Undergraduate Student Theses

Plants are generally grown using soil as the main medium to supply the essentials necessary for growth, but as population grows and land decreases it is important to expand the knowledge of other growth mediums such as hydroponics. The purpose of this study is to provide information on hydroponic growing systems, specifically how the pH of the water effects cucumber plant growth and if different varieties of cucumber plants may have varying reactions to the pH. The hypothesis was that the plants would grow efficiently at pH of 5.0 and worst at pH of 7.5. This experiment was conducted in …

Sustainable Dietary Solutions To A Multi-Dimensional Epidemic: A Practical Application Of The Mediterranean Diet To Nebraska, Samuel A. Virgillito

Department of Environmental Studies: Undergraduate Student Theses

There is substantial evidence to suggest the major health and environmental benefits of the Mediterranean diet. When compared to the Western Pattern diet, the Mediterranean diet consistently ranks higher by both of these measures. Considering a looming environmental crisis and an already present health epidemic, a major dietary shift and overhaul of the current food system in America is necessary. Yet few studies aim to suggest the transferability of the Mediterranean diet to regions outside of the Mediterranean basin. Nebraska offers a unique case study as it reflects the contextually poor health of Americans and boasts a massive agriculture industry …

What Are The Prospects For -Omics-Based Molecular Technologies In Cancer Diagnostics And Treatment, Katya Eriksen

Department of Environmental Studies: Undergraduate Student Theses

Cancer remains one of the leading causes of death in the United States, following the heart disease. New technologies are needed to fight and eventually to eradicate cancer. Omic technologies is a new emerging field of cancer research that may offer cancer patients long awaited opportunities to get faster, more precise personalized medical care, while letting doctors do their job more effectively. The rapid development of omic technologies and large datasets promise a new type of health care system when the patients can be treated according to their own individualized molecular characteristics.

Anthocyanin Stability In Food Products Made With Freeze-Dried Blueberry Powder, Samantha Findley

Food Science Undergraduate Honors Theses

This study evaluated the stability of anthocyanins in six blueberry products (gummy, graham bar, oatmeal bar, rice krispy bar, ice pop and juice) prepared with freeze-dried wild blueberry powder during processing and over eight weeks storage. Total anthocyanins were determined by HPLC before processing and at day 0 and 2, 4, 6, and 8 weeks of storage. Thermal processing of gummy and graham bar products resulted in significant losses of anthocyanins (50% and 31%, respectively). An eight-week storage time also resulted in a significant decrease in anthocyanins (7% to 51%) in products stored at ambient temperature. The ice pop, which …

What Can We Do? Puzzling Over The Interpretation Of Heredity And Variation From Galton To Genetic Engineering, Peter J. Taylor

Working Papers on Science in a Changing World

First six chapters of a book motivated as follows: When I had mentioned to colleagues that I was exploring some significant issues overlooked by both sides in nature-nurture debates, the typical response was “we know, of course, that nature and nurture are intertwined”; they never asked “which nature-nurture science are you referring to?” It occurred to me that, in the long history of nature-nurture debates, opposing sides had always assumed or implied that these different scientific approaches were speaking to the same issues. If that were the case, then the challenge—something I was already puzzling over—was how best to draw …

Lighting And Economic Considerations For A Hydroponic S-Based Greenhouse At Tri Cycle Farms, Laura Gray

Biological and Agricultural Engineering Undergraduate Honors Theses

Hydroponics is an agricultural technology that involves growing plants without soil, instead using other growth media with added nutrients, typically inside a controlled facility such as a greenhouse. Hydroponics-based agriculture has a number of benefits, namely that it is more water efficient, requires less intensive labor, yields higher quality crops consistently in shorter time, and is easier to control. It also has the potential to be economically advantageous, due to its ability to grow certain crops in the off-season. In Fayetteville, Arkansas, a non-profit urban farm known as Tri Cycle Farms has been seeking a way to design, build, and …

Influence Of Environmental Conditions On Fatty Acid-Induced Changes In Vibrio Cholerae Persistence And Pathogenicity, Abigail Doyle

Honors Theses

Vibrio cholerae, a Gram-negative bacterium, is responsible for the acute intestinal infection known as cholera. This illness is due in part to V. cholerae’s ability to sense and adapt to changing environments as it is ingested into the human body from brackish environments. It was shown in recent studies that this bacteria has the ability to uptake exogenous fatty acids, resulting in changes to V. cholerae persistence and pathogenicity. The aim of this research is to determine the extent to which these additional exogenous UFAs influence the persistence and pathogenicity of V. cholerae throughout its transitional period from brackish environments …

Fingerprint Analysis: Moving Toward Multiattribute Determination Via Individual Markers, Morgan Eldridge

Chemistry

Forensic science will be forever revolutionized if law enforcement can identify personal attributes of a person of interest solely from a fingerprint. For the past five years, the goal of the Halamek Lab has been to establish a way to identify originator attributes. Specifically, biological sex has been accomplished and the ultimate goal is to continue to accomplish this using a single analyte for each. To date, an enzymatic assay and two chemical assays have been developed for the analysis of multiple analytes. In this thesis, an additional enzymatic assay has been developed. This time, however, the assay utilizes only …

Two-Stage Mixed Integer Stochastic Programming And Its Application To Bond Portfolio Optimization, Nasser Aedh Alreshidi

Theses and Dissertations

We consider a two-stage stochastic bond portfolio optimization problem, where an investor aims to optimize the cost of bond portfolio under different scenarios while ensuring predefined liabilities during a given planning horizon. The investor needs to optimally decide whether to buy, hold, or sell bonds based upon present market conditions under different scenarios and varying assumptions, where the scenarios are determined based on interest rates and buying prices of the bonds. Three stochastic integer programming models are proposed and applied to real-data from Saudi Sukuk (Bond) Market. The case-study results demonstrate the varying optimal decisions made to manage bond portfolio …

Effects Of Global Warming On Gonadal Functions, Cellular Apoptosis, And Oxidative Stress In The American Oyster, Sarah B. Nash

Theses and Dissertations

Global warming due to climate change is predicted to intensify the heat stress in marine and coastal organisms, affecting their development, growth and reproductive functions. In this study. I analyzed gonadal development, heat shock protein 70 (HSP70), nitrotyrosine protein (NTP), dinitrophenyl (DNP) expressions, cellular apoptosis, and coelomic fluid (CF) conditions in American oyster. Oysters were placed in six aquariums and exposed to control (24°C), medium (28°C), and high (32°C) temperatures for one week. Higher temperature significantly decreased the number of eggs and sperm. CF protein concentrations also declined compared to control. In contrast, CF pH and HSP70 expression in gonad …

Telomeres, Nutrition And Mortality: Risk Factors For The Rate Of Telomere Length Decline And The Associations Between Telomere Length, Nutrition And Mortality, Saruna Ghimire

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Telomeres are nucleoprotein structures located at the ends of eukaryotic chromosomes, thought to protect the DNA from damage. As a person experiences stressors, harmful exposures, and other diseases throughout their life, telomeres are thought to become damaged and their length shortened, decreasing their ability to protect the DNA. Nutrition is an important aspect of healthy aging. Preservation of telomere length (TL) is thought to be one of the mechanisms by which good nutrition can delay or prevent the development of chronic disease and death. Recent evidence of preservation of TL with good nutrition is promising. Thus, the aim of …

Riding My Bike In Paradise With Margaret Fuller: A Phenomenological Study, Nanette Rasband Hilton

UNLV Theses, Dissertations, Professional Papers, and Capstones

Margaret Fuller (1810-1850) was perhaps the most famous American woman during the nineteenth century. After her tragic death, reprints of her best-selling books were heavily edited and she was nearly forgotten. During and after her lifetime, Fuller fell victim to the phenomenological alterity identified and defined by theorists including Derrida and Edward Said as Othering. She spent her career combating Othering in all its forms. Through the lens of both social identity theory and multiple identity theory this study examines how Fuller grappled with social prescriptions. As an autodidact, she mined diverse literary resources to construct heterogeneous texts that cultivate …

The Effects Of Injury On Running Status And Gait Biomechanics, Kristyne Wiegand

UNLV Theses, Dissertations, Professional Papers, and Capstones

Over the past several decades, endurance running has grown steadily as a popular form of physical activity. Running is easily accessible, does not require expensive equipment, and can be performed without specific skill training. Individuals who run also experience health benefits like increased cardiovascular health and reduced risk of all-cause morbidity. Despite these benefits, running is also associated with high rates of musculoskeletal injury. Although researchers have attempted to identify injury risks and mitigate the incidence of running injury, there is still no consensus as to why runners become injured. Research has also attempted to identify biomechanical movement patterns that …

Generalized And Higher Dimensional Apollonian Packings, Daniel Lautzenheiser

UNLV Theses, Dissertations, Professional Papers, and Capstones

In this thesis, we show that circle, sphere, and higher dimensional sphere packings may

be realized as subsets of the boundary of hyperbolic space, subject to certain symmetry

conditions based on a discrete group of motions of the hyperbolic space. This leads to

developing and applying counting methods which admit rigorous upper and lower bounds on

the Hausdorff (or Besikovitch) dimension of the residual set of several generalized Apollonian

circle packings. We find that this dimension (which also coincides with the critical exponent

of a zeta-type function) of each packing is strictly greater than that of the Apollonian

packing, supporting …

Ecological Responses To Eutrophication And Restoration In A Shallow Subtropical Estuary, Xiao Ma

Theses and Dissertations

Like many other estuaries in the world, the Indian River Lagoon (IRL) is experiencing serious environmental health challenges in recent years. Ecosystem challenges include the connected phenomena of Harmful Algal Blooms (HABs) due to eutrophication and accumulation of fine-grained organic-rich sediments on the benthos. Fine-grained organic-rich sediments, referred to as “muck”, is a source of nutrients and fuels algal blooms in the water column, and excess particles associated with algal blooms sink to bottom and contribute to muck. This dissertation aims to better understand these problems by addressing two main objectives: first, to determine whether key herbivorous mesozooplankton have the …

Food Insecurity Among University Of Nebraska–Lincoln Students, Lindsey Bremer

Department of Environmental Studies: Undergraduate Student Theses

A survey of 38 University of Nebraska-Lincoln students was conducted to determine the food insecurity levels of respondents. Food insecurity is defined as limited or uncertain availability of nutritionally adequate and safe foods or limited or uncertain ability to acquire acceptable foods in socially acceptable ways (Bickel et al, 2000). A systematic review of 8 food security studies on college and university students found an average food insecurity level of 43.5%, (Nazmi et al, 2018) while the national level is 11.8% (Coleman-Jensen et al, 2017). The research was driven by the question, What is the food insecurity rate among University …

Effects Of Elevated Temperature On Gonadal Functions, Cellular Apoptosis, And Oxidative Stress In Atlantic Sea Urchin (Arbacia Punctulata), Jackson B. Johnstone

Theses and Dissertations

Increasing surface sea water temperatures effect on growth, reproduction and development in marine organisms. Sea urchins are excellent indicator species and ideal model organisms to focus on. In this study, I tested the effect of higher temperatures on reproductive functions, heat shock protein (HSP, a chaperone protein produced by cells in response to heat stress) and nitrotyrosine protein (NTP, an indicator of reactive nitrogen species, RNS) expressions, cellular apoptosis, and ceolomic fluid (CF, a body fluid which regulates important physiological processes) conditions in Atlantic sea urchin at three different temperatures. Ten sea urchins were placed in each of six aquariums …

Health Disparities Among Sexual And Gender Minorities, Jennifer Keeley

UNLV Theses, Dissertations, Professional Papers, and Capstones

Decades of research has shown that sexual and gender minorities (SGMs) experience adverse health and mental health outcomes to a greater extent than their heterosexual peers. The need to better understand and eliminate health disparities in the SGM population was recognized by the National Institute on Minority Health and Health Disparities (NIMHD) at NIH. The Secretary of Health at the Department of Health and Human Services approved the designation of the SGM population as a health disparities population in 2016 and called for SGM studies to examine the health needs of the SGM population across SGM subgroups via large representative …

The Evaluation Of Low-Use-Rate Zinc Fertilization Strategies On Seedling Canopy Coverage, Zn Concentration, Biomass, And Grain Yield, Maxwell David Coffin

Graduate Theses and Dissertations

Zinc (Zn) is the most common micronutrient deficiency in flooded rice (Oryza sativa L.). Some new Zn fertilization methods have been advertised, but have limited research supporting their efficacy. This study mainly compared the effect of Zn-seed treatment rate in combination with other low-use-rate Zn-fertilization methods to the standard of 11 kg Zn ha-1 as ZnSO4 on rice early-season canopy cover, tissue-Zn concentration, and grain yield. A secondary objective evaluated an alternative method (to seed treatment with ZnO) of enhancing seed-Zn concentration using post-heading foliar-Zn application on seedling tissue-Zn concentration and grain yield. For the main objective, rice seed was …

Assessment Of Heavy Metals In Subsistence-Harvested Alaskan Marine Mammal Body Tissues And Vibrissae, Pilar M. Ferdinando

HCNSO Student Theses and Dissertations

The coastal, indigenous communities around Alaska have subsisted on marine animals for generations, often focusing on large apex predators such as seals, sea lions, and whales. Three species of pinnipeds (harbor seal, Steller sea lion, northern fur seal) and the northern sea otter have all undergone significant population declines since the 1970s, some regions more than others. Archived vibrissae (whiskers) and body tissues from these four species were available from the Bering Sea and throughout the Gulf of Alaska from the 1990s and early 2000s. Tissues from these species are exceedingly difficult to obtain; thus, the archived tissues provided a …

Assessing Woody Species In The Philadelphia Urban Forest: Foraging Potential Versus Actual Practices, Sarah Becker

Environment and Sustainability Presentations

No abstract provided.