Digital Commons Network^™

Structural Annotation Of Electro- And Photochemically Generated Transformation Products Of Moxidectin Using High-Resolution Mass Spectrometry, Lisa Kotthoff, Sarah-Louise O'Callaghan, Jan Lisec, Tanja Schwerdtle, Matthias Koch

Articles

Moxidectin (MOX) is a widely used anthelmintic drug for the treatment of internal and external parasites in food-producing and companion animals. Transformation products (TPs) of MOX, formed through metabolic degradation or acid hydrolysis, may pose a potential environmental risk, but only few were identified so far. In this study, we therefore systematically characterized electro- and photochemically generated MOX TPs using high-resolution mass spectrometry (HRMS). Oxidative electrochemical (EC) TPs were generated in an electrochemical reactor and photochemical (PC) TPs by irradiation with UV-C light. Subsequent HRMS measurements were performed to identify accurate masses and deduce occurring modification reactions of derived TPs …

Evolutionary Origins, Regulation, And Function Of Carotenoid Biosynthesis In The Marine Heterotrophic Eukaryote, Aurantiochytrium Limacinum, Mariana Rius

SoMAS Research Data

Thraustochytrids are abundant and ubiquitous marine protists that are important in global elemental cycling and in supporting oceanic food webs through de novo omega-3 polyunsaturated fatty acid production. Thraustochytrids are also one of few heterotrophic eukaryotes with the capacity to synthesize carotenoids, a class of antioxidative pigments made up of carotenes (e.g., β-carotene) and xanthophylls (e.g., astaxanthin). Heterotrophic production of carotenoids is typically associated with protection against oxidative stress, yet the eco-physiological role and evolutionary origin of thraustochytrid carotenoid production remain elusive. A. limacinum encodes the first three carotenoid biosynthesis-specific enzymes (phytoene synthase, phytoene desaturase, and lycopene cyclase) in a …

Studies On The Size And Non-Planarity Of Aromatic Stacking Moiety On Conformation Selectivity And Thermal Stabilization Of G-Quadruplexes, Mandeep Singh

University of the Pacific Theses and Dissertations

Targeting DNA has the advantage over proteins for cancer remediation because of the fewer copies of the ligands required for the desired therapeutic effect. Traditionally, covalent DNA binders like alkylating agents have been used to induce genetic instability through the formation of DNA lesions and strand breaks, leading to cellular apoptosis. The primary drawback of this treatment is the non-specific binding that affects both cancerous and non-cancerous cells. G-quadruplexes are the DNA secondary structures that are present in abundance near the promoter regions of the oncogenes and are involved in the regulation of their activities. A ligand-mediated stabilization of G-quadruplexes …

Research And Innovation As A Catalyst For Food System Transformation, A.C.L. Den Boer, K.P.W. Kok, M. Gill, J. Breda, Jean Cahill, C. Callenius, P. Caron, Z. Damianova, M. Gurinovic, L. Lahteenmaki, T. Lang, R. Sonnino, G. Verburg, H. Westhoek, T. Cesuroglu, B.J. Regeer, J.E.W. Broerse

Research and Innovation - Other

Background Food systems are associated with severe and persistent problems worldwide. Governance approaches aiming to foster sustainable transformation of food systems face several challenges due to the complex nature of food systems.

Scope and approach In this commentary we argue that addressing these governance challenges requires the development and adoption of novel research and innovation (R&I) approaches that will provide evidence to inform food system transformation and will serve as catalysts for change. We first elaborate on the complexity of food systems (transformation) and stress the need to move beyond traditional linear R&I approaches to be able to respond to …

Effects Of Integrated Application Of Plant-Based Compost And Urea On Soil Food Web, Soil Properties, And Yield And Quality Of A Processing Carrot Cultivar, A. Habteweld, D. Brainard, A. Kravchencko, Parwinder Grewal, H. Melakeberhan

School of Earth, Environmental, & Marine Sciences Faculty Publications

Soil nutrient management system characterized by reduced input of inorganic fertilizers integrated with organic amendments is one of the alternatives for reducing deleterious environmental impact of synthetic fertilizers, suppressing soil-borne pests and diseases, and improving soil health and crop yield. A hypothesis of the present study was that lower rates of urea mixed with higher rates of plant compost (PC) would improve nematode community structure, soil food web condition, soil biological, and physiochemical properties, and yield and quality of a processing carrot (Daucus carota) cultivar. Urea and PC were each applied at 135kg nitrogen (N)/ha alone or at 3:1, 1:1, …

Nonparametric Misclassification Simulation And Extrapolation Method And Its Application, Congjian Liu

College of Graduate Studies: Theses & Dissertations

The misclassification simulation extrapolation (MC-SIMEX) method proposed by Küchenho et al. is a general method of handling categorical data with measurement error. It consists of two steps, the simulation and extrapolation steps. In the simulation step, it simulates observations with varying degrees of measurement error. Then parameter estimators for varying degrees of measurement error are obtained based on these observations. In the extrapolation step, it uses a parametric extrapolation function to obtain the parameter estimators for data with no measurement error. However, as shown in many studies, the parameter estimators are still biased as a result of the parametric extrapolation …

No Soldiers Left Behind: An Iot-Based Low-Power Military Mobile Health System Design, James Jin Kang, Wencheng Yang, Gordana Dermody, Mohammadreza Ghasemian, Sasan Adibi, Paul Haskell-Dowland

Research outputs 2014 to 2021

© 2013 IEEE. There has been an increasing prevalence of ad-hoc networks for various purposes and applications. These include Low Power Wide Area Networks (LPWAN) and Wireless Body Area Networks (WBAN) which have emerging applications in health monitoring as well as user location tracking in emergency settings. Further applications can include real-Time actuation of IoT equipment, and activation of emergency alarms through the inference of a user's situation using sensors and personal devices through a LPWAN. This has potential benefits for military networks and applications regarding the health of soldiers and field personnel during a mission. Due to the wireless …

End-Permian (252 Mya) Deforestation, Wildfires And Flooding—An Ancient Biotic Crisis With Lessons For The Present, Vivi Vajda, Stephen Mcloughlin, Chris Mays, Tracy D. Frank, Christopher R. Fielding, Allen Tevyaw, Veiko Lehsten, Malcolm Bocking, Robert S. Nicoll

Department of Earth and Atmospheric Sciences: Faculty Publications

Current large-scale deforestation poses a threat to ecosystems globally, and imposes substantial and prolonged changes on the hydrological and carbon cycles. The tropical forests of the Amazon and Indonesia are currently undergoing deforestation with catastrophic ecological consequences but widespread deforestation events have occurred several times in Earth’s history and these provide lessons for the future. The end-Permian mass-extinction event (EPE; ∼252 Ma) provides a global, deep-time analogue for modern deforestation and diversity loss. We undertook centimeter-resolution palynological, sedimentological, carbon stable-isotope and paleobotanical investigations of strata spanning the end- Permian event at the Frazer Beach and Snapper Point localities, in the …

Transformative Education In Agroecology: Student, Teacher, And Client Involvement In Co-Learning, Charles A. Francis, Anna Marie Nicolaysen, Geir Lieblein, Tor Arvid Breland

Department of Agronomy and Horticulture: Faculty Publications

Educational methods have evolved rapidly in agroecology, which is a complex and holistic field without a long history or the formal tradition of any single academic discipline. Definitions of agroecology have evolved from its initial conception as a marriage of agriculture with ecology, to an aggregation of different paths including science, practices, and movements, and recently as a broad appreciation of the ecology of food systems. In contrast with traditional courses that begin with a history of the discipline and review the contributions of early leaders, we have embraced phenomenology to firmly establish roots in students’ learning through their experiences …

A Proposed Mechanism To Induce Multi-Layer Polydiacetylene-Coated Filter Color Response To Bacteria , Timothy Hanks

Chemistry Publications

The purpose of this study was to develop a multi-layer diacetylene (PDA)-coated filter and to verify the proposed color response mechanism of PDA-coated filters to bacteria. Unlike other reports which immobilize PDA lipo- somes on solid support or create monolayer Langmuir films, multi-layer PDA-coated filters were generated by directly evaporating organic solvents. Different from incorporating functional headgroups or inserting phospho- lipids into PDA, we reported that bacterial growth can trigger the color change of PDA sensors without any mod- ification or phospholipid insertion. The mechanism that pH change from bacteria metabolites lead to color change of PDA filter was proposed …

Exploring Substrate Specificity Of Fructose Transporters En Route To Glut Specific Probes For Biochemical And Biomedical Applications, Vagarshak Vigenovich Begoyan

Dissertations, Master's Theses and Master's Reports

Carbohydrate Transporters (GLUTs) are responsible for the transportation of sugars into the cell and have been of great interest in research for decades. Alterations or mutations that result in overexpression of GLUTs have been linked to a great number of diseases including, obesity, diabetes, and cancer. Differentiation between transporters has been shown to be incredibly difficult due to the highly conserved nature of the transporter structure, and thus specific targeting of transporters has proven a difficult challenge. Additionally, the GLUTs have been shown to high flexibility in their conformations, so it is difficult to determine what can or cannot pass …

Assessing The Accuracy Of A Uav Snow Depth Survey: Utqiagvik (Barrow), Alaska Calm Grid, Ian Nichols

Dissertations, Master's Theses and Master's Reports

Active layer depth and snow depth are annually collected across the Circumpolar Active Layer Monitoring (CALM) Network to observe the response of the active layer and near-surface permafrost to climate change over decadal-time scales. Snow depth is typically measured using a graduated steel probe at each grid node but, in this paper, we explore the viability of using Unmanned Aerial Vehicle (UAV) (drone) technology to collect snow depth measurements at the 1 km² Utqiagvik (Barrow), Alaska CALM grid. This is achieved by comparing estimated UAV snow depths to measured snow depths collected using a MagnaProbe (MP) at each of …

Quantifying Water Recharge And Water Use In Hand Dug Wells: A Case Study Of Thiawor, Senegal, West Africa, Celine Carus

Dissertations, Master's Theses and Master's Reports

For many rural communities in Senegal, water is an essential life-giving need received only through a network of hand dug wells. Increasing rainfall variability in the Sahel has driven greater water insecurity for those communities that rely on rain-irrigated systems for agriculture. This study investigates the retrieval, purposes, and quantities of seasonal water usage on a small domestic scale, as well as an analysis of perceived water availability in the wells during the rainy season. Additionally, using a combination of interview data and pumping test data obtained from the village wells, water usage and estimated daily needs are calculated and …

Torrefaction Of Cassava Rhizome For Catalytic Gasification Process With Mcm-41 Synthesis By Illite Waste, Punchaluck Sirinwaranon

Chulalongkorn University Theses and Dissertations (Chula ETD)

In this research, the cassava rhizome (CR) was torrefied under different atmosphere to produce a superior green solid fuel for subsequent catalytic gasification. The research consists of 3 parts. The first part was to study the effect of torrefaction temperature (220–300°C) under nitrogen (N2) and simulated flue gas (SFG) at a residence time of 30 and 60 minutes. The highest carbon content in obtained solid fuel ranged from 51.45–65.09%, meanwhile the lowest oxygen content was 19.36% at a temperature over 260˚C. The decrease of O/C ratio benefited from the fuel characteristics improvement of torrefied CR. The higher heating value of …

Urban Food Sovereignty: Urgent Need For Agroecology And Systems Thinking In A Post-Covid-19 Future, Ali Loker, Charles A. Francis

Department of Agronomy and Horticulture: Faculty Publications

The current COVID-19 pandemic has brought attention to challenges associated with our dominant industrial food system in the U.S. The general public now has more appreciation for farm workers and meatpacking employees, as well as those in grocery stores and in food transportation who are suddenly recognized as essential frontline workers. It apparently takes a crisis for us to focus clearly on the fragility of this system and the lives of people on whom we depend. In this commentary we discuss the definition of food sovereignty, how it manifests in urban areas, and how the COVID-19 pandemic can trigger viable …

Managing Forest Disturbances: Effects On Mule Deer And Plant Communities In Montana's Northern Forests, Teagan Ann Hayes

Graduate Student Theses, Dissertations, & Professional Papers

Mule deer (Odocoileus hemionus) are frequently the focus of population and habitat management in the western United States. Land and wildlife managers use disturbance to reset forests to earlier successional stages and improve the quality and quantity of forage available to mule deer. However, the effects of management practices on nutrition and selection vary widely, so the implementation of management practices raises ecological as well as management-related concerns. This work investigated how disturbance from wildfire, prescribed fire, and timber harvest influences the spatial and temporal distribution of nutritional resources in mule deer summer range, and therefore, how the …

A Short Remark On Multipurpose Laser Therapy “Helios” In Ukraine And Its Potential Application For Treatment Of Neurology Disorders, Florentin Smarandache, Volodymyr Krasnoholovets, Victor Christianto, Rizha Vitania, The Houw Liong

Branch Mathematics and Statistics Faculty and Staff Publications

However, a truly multipurpose laser therapy method is very rarely available. Here we introduce a multipurpose laser therapy device in Ukraine, which is capable to take care a multitude of diseases. It is called “Helios”, by one of us (VK). We also give a case where a patient who suffered from Covid-19 has been treated successfully until he is recovered to healthy condition. In the last section we also discuss potential future application of Helios for other fields; i.e. neurology disorders.

Three Possible Applications Of Neutrosophic Logic In Fundamental And Applied Sciences, Victor Christianto, Robert Neil Boyd, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

In Neutrosophic Logic, a basic assertion is that there are variations of about everything that we can measure; the variations surround three parameters called T,I,F (truth, indeterminacy, falsehood) which can take a range of values. This paper shortly reviews the links among aether and matter creation from the perspective of Neutrosophic Logic. Once we accept the existence of aether as physical medium, then we can start to ask on what causes matter ejection, as observed in various findings related to quasars etc. One particular cosmology model known as VMH (variable mass hypothesis) has been suggested by notable astrophysicists like Halton …

Sex And Age Differences In Prevalence And Risk Factors For Prediabetes In Mexican-Americans, Kristina Vatcheva, Belinda M. Reininger, Susan P. Fisher-Hoch, Joseph B. Mccormick

School of Mathematical & Statistical Sciences Faculty Publications

AIMS:

Over 1/3 of Americans have prediabetes, while 9.4% have type 2 diabetes. The aim of our study was to estimate the prevalence of prediabetes in Mexican Americans, with known 28.2% prevalence of type 2 diabetes, by age and sex and to identify critical socio-demographic and clinical factors associated with prediabetes.

METHODS:

Data were collected between 2004 and 2017 from the Cameron County Hispanic Cohort in Texas. Weighted crude and sex- and age- stratified prevalences were calculated. Survey weighted logistic regression analyses were conducted to identify risk factors for prediabetes.

RESULTS:

The prevalence of prediabetes (32%) was slightly higher than …

Effects Of Wild Pig Disturbance On Forest Vegetation And Soils, Steven M. Gray, Gary J. Roloff, Daniel B. Kramer, Dwayne R. Etter, Kurt C. Vercauteren, Robert A. Montgomery

United States Department of Agriculture Wildlife Services: Staff Publications

In North America, wild pigs (Sus scrofa; feral pigs, feral swine, wild boars) are a widespread exotic species capable of creating large‐scale biotic and abiotic landscape perturbations. Quantification of wild pig environmental effects has been particularly problematic in northern climates, where they occur only recently as localized populations at low densities. Between 2016 and 2017, we assessed short‐term (within ~2 yrs of disturbance) effects of a low‐density wild pig population on forest features in the central Lower Peninsula of Michigan, USA. We identified 16 8‐ha sites using global positioning system locations from 7 radio‐collared wild pigs for sampling.Within each …

Timing And Extent Of Crop Damage By Wild Pigs (Sus Scrofa Linnaeus) To Corn And Peanut Fields, C. M. Boyce, Kurt C. Vercauteren, James C. Beasley

United States Department of Agriculture Wildlife Services: Staff Publications

The global expansion of wild pigs over the last few decades has resulted in an increase in extent and distribution of damages to crops, placing a growing strain on agricultural producers and land managers. Despite the extent of wild pig damage to agriculture, there is little data regarding timing and spatial variability of damage to corn (Zea mays Linnaeus) and we found no data regarding the effect of these factors on peanuts (Arachis hypogaea Linnaeus). Our objective was to determine the timing and extent of wild pig damage to corn and peanut fields, as well as the extent …

The Role Of European Starlings (Sturnus Vulgaris) In The Dissemination Of Multidrug- Resistant Escherichia Coli Among Concentrated Animal Feeding Operations, Jeffrey C. Chandler, Jennifer E. Anders, Nicolas A. Blouin, James C. Carlson, Jeffrey T. Lejeune, Lawrence D. Goodridge, Baolin Wang, Leslie A. Day, Anna M. Mangan, Dustin A. Reid, Shannon M. Coleman, Matthew W. Hopken, Bledar Bisha

United States Department of Agriculture Wildlife Services: Staff Publications

Antimicrobial use in livestock production is a driver for the development and proliferation of antimicrobial resistance (AMR). Wildlife interactions with livestock, acquiring associated AMR bacteria and genes, and wildlife’s subsequent dispersal across the landscape are hypothesized to play an important role in the ecology of AMR. Here, we examined priority AMR phenotypes and genotypes of Escherichia coli isolated from the gastrointestinal tracts of european starlings (Sturnus vulgaris) found on concentrated animal feeding operations (CAFOs). European starlings may be present in high numbers on cAfos (>100,000 birds), interact with urban environments, and can migrate distances exceeding 1,500 km in North …

Effects Of Brodifacoum And Diphacinone Exposure On Four Species Of Reptiles: Tissue Residue Levels And Survivorship, Richard E. Mauldin, Gary W. Witmer, S. A. Shriner, Rachael S. Moulton, Katherine E. Horak

United States Department of Agriculture Wildlife Services: Staff Publications

BACKGROUND: Anticoagulant rodenticides are used worldwide to control pest rodent species. However, the risks posed to nontarget reptiles have not been well characterized. In this study, 46 giant ameivas (Ameiva ameiva), 39 boa constrictors (Boa constrictor), 33 wood turtles (Rhinoclemmys pulcherrima), and 47 green iguanas (Iguana iguana) were orally dosed with one of two levels of either diphacinone or brodifacoum anticoagulant in propylene glycol solutions. Dosages were derived using daily food intake (DFI) equations, converting DFI to an equivalent anticoagulant bait amount and gavaging the solution volume needed to deliver the quantity of anticoagulant in that amount of bait. Animals …

Competing Reproductive And Physiological Investments In An All‑Female Lizard, The Colorado Checkered Whiptail, Lise M. Aubry, Spencer B. Hudson, Bryan M. Kluever, Alison C. Webb, Susannah S. French

United States Department of Agriculture Wildlife Services: Staff Publications

Organisms in the wild have to allocate limited resources towards competing functions such as reproduction, growth, and self-maintenance. These competing investments create significant changes in physiological activity, and we still know little about the relationship between physiological activity and reproductive investment in natura. We investigated trade-offs between physiological activity and reproductive investment in the parthenogenetic Colorado checkered whiptail, Aspidoscelis neotesselata, across three different sites at the US Army Fort Carson Military Installation near Colorado Springs, CO, through-out the reproductive season in 2018 and 2019. We measured clutch size and reproductive activity and quantified plasma corticosterone (CORT), reactive oxygen metabolites (ROMs), …

Historic And Contemporary Use Of Catfish Aquaculture By Piscivorous Birds In The Mississippi Delta, Paul C. Burr, Jimmy L. Avery, Garrett M. Street, Bronson K. Strickland, Brian S. Dorr

United States Department of Agriculture Wildlife Services: Staff Publications

Piscivorous birds are the primary source of catfish (Ictalurus spp.) depredation at aquaculture facilities in northwestern Mississippi. Of particular concern is the Double-crested Cormorant (Phalacrocorax auritus), which can cost aquaculture producers millions of dollars annually through the depredation of cultured fish. Historical research conducted in the early 2000s estimated cormorant use of aquaculture ponds in the region, but aquaculture area has decreased by more than 70% since those estimates were made. With less aquaculture available, we predicted cormorant densities on aquaculture would be greater today than historically. Applying a similar methodology as in historical studies, we used …

Movement Behavior Of Radio-Tagged European Starlings In Urban, Rural, And Exurban Landscapes, Page E. Klug, H. Jeffrey Homan

United States Department of Agriculture Wildlife Services: Staff Publications

Since their intentional introduction into the United States in the 1800s, European starlings (Sturnus vulgaris) have become the fourth most common bird species and a nuisance bird pest in both urban and rural areas. Managers require better information about starling movement and habit-use patterns to effectively manage starling populations and the damage they cause. Thus, we revisited 6 radio-telemetry studies conducted during fall or winter between 2005 and 2010 to compare starling movements (n = 63 birds) and habitat use in 3 landscapes. Switching of roosting and foraging sites in habitat-sparse rural landscapes caused daytime (0900–1500 hours) …

Serum Chemistry Values In Wild Black Vultures In Mississippi, Usa, Fred L. Cunningham, Sherman W. Jack, Amanda R. Deese, Eric R. Wengert, Kyle Van Why, Carla L. Huston, Scott Lemmons, Richard B. Minnis

United States Department of Agriculture Wildlife Services: Staff Publications

Vultures (Cathartidae and Accipitridae) play an important role in ecosystem balance by rapidly disposing animal carcasses and thus preventing the potential spread of pathogens. Blood chemistry values provide a means of assessing the health of wildlife and wild animal populations; however, there are significant differences in chemistries among species and when comparing captive and free-living New and Old World vultures. In 2007, we collected blood serum from 30 female and 14 male wild, healthy black vultures (Coragyps atratus) live-trapped by the U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Wildlife Services from a power substation in …

Understanding The Connections: An Analysis Of Climate Change And Human Security, Erica Martinez

Open Access Theses & Dissertations

Increasing evidence shows that the impacts of anthropogenic climate change have magnified and will have dramatic implications for both the natural and social systems (Adger et al., 2014). While research on the security implications of climate change has been found to have a major bearing on policy making, experts have not reached a consensus about how climate change and human security are related, leaving the climate-security nexus and corresponding policies underdeveloped.

The purpose of this study is to delineate and scrutinize the relationship between climate change and human security so that a more comprehensive understanding of the phenomenon is achieved. …

Partitioning Variation In Vegetation And Landscape Functionality In Arid Land Piosphere, Eahsan Shahriary

Open Access Theses & Dissertations

A piosphere is an interaction between vegetation community, watering point, and grazing livestock/wildlife. In this Dissertation, I begin by reviewing the concept of the piosphere, and the progress, knowledge gaps and common statistical approaches and errors in piosphere research. Landscape functionality, plant community distribution and their influencing factors on a piosphere in Iran are then investigated.

A total 862 piosphere publications of multiple types from 68 countries and 10 different languages during the period of 1915 â?? 2018 were reviewed. Australia was the most productive country followed by South Africa, the USA, Botswana and Argentina. Ivan Thrash is the most …

Morphological And Heartwood Variation Of Santalum Macgregorii In Papua New Guinea, T. Page, G. K. Jeffrey, P. Macdonell, D. Hettiarachchi, Mary C. Boyce, A. Lata, L. Oa, G. Rome

Research outputs 2014 to 2021

© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Santalum macgregorii (sandalwood), which is endemic to the southern part of Papua New Guinea (PNG), has been heavily exploited for its fragrant heartwood and is classified as threatened across its natural range. Domestication and smallholder agroforestry offer the means to preserve remaining diversity. This study was undertaken to understand the extent of remaining natural variation to support the species’s conservation and domestication. We evaluated morphological, heartwood and essential oil characters in 126 S. macgregorii trees in five populations (districts) in PNG’s Central, Gulf and Western …