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Physical And Chemical Study Of Interaction In The Urea–Valine System For The Creation Of Modified Liquid Nitrogen Fertilizers, Suvonkul Erkhanovich Nurmonov, Saydullo Khamidovich Azimov Mar 2026

Physical And Chemical Study Of Interaction In The Urea–Valine System For The Creation Of Modified Liquid Nitrogen Fertilizers, Suvonkul Erkhanovich Nurmonov, Saydullo Khamidovich Azimov

Chemical Technology, Control and Management

This study reports the results of a comprehensive physicochemical investigation of the urea–L-valine binary system, conducted to validate its potential as a modified base for liquid nitrogen fertilizers.

By utilizing the methods of isomolar series, visual-polythermal analysis, X-ray phase (XRD) and single-crystal X-ray diffraction (SC-XRD), synchronous thermal analysis (TGA/DTA), and FT-IR spectroscopy, it was determined that the interaction between components in both aqueous solutions and the solid phase results in the formation of molecular associates stabilized by hydrogen bonds, without the formation of new stoichiometric compounds.

The concentration and temperature limits of the system's stability were defined, revealing a reduction …


The Need For Developing Psychologically Informed Physical Therapy Education, Dustin Cox Mar 2026

The Need For Developing Psychologically Informed Physical Therapy Education, Dustin Cox

Journal of Applied Disciplines

Chronic pain presents a multifaceted challenge for healthcare providers, often impacting patients' physical, emotional, and psychological well-being. Research indicates that individuals with chronic pain process pain through emotional and reward pathways in the brain, underscoring the need for integrative treatment approaches. Evidence supports the effectiveness of combining psychological interventions with physical rehabilitation to improve outcomes. Acceptance and Commitment Therapy (ACT), a mindfulness-based behavioral therapy, has shown promise in addressing the psychological dimensions of chronic pain. However, physical therapists often lack formal training in ACT. This study protocol was designed to explore effective methods for educating physical therapists in ACT principles …


Time-Dependent Amplification Of Growth Rates In A Plankton-Oxygen Model, Rapha Coutin Mar 2026

Time-Dependent Amplification Of Growth Rates In A Plankton-Oxygen Model, Rapha Coutin

Master's Theses

Near-bottom hypoxia occurs when dissolved oxygen levels drop to a level that is harmful to marine biology, creating biological dead zones along the ocean floor. Recent years have seen a dramatic increase in the percentage of coastal, near-bottom, hypoxic water, with the average in 2021 nearly double that of the average from 2009 to 2018 and about twenty-eight times the average from 1950 to 1980. Recent literature has linked this increase in oceanic hypoxia to the increase in upwelling-favorable winds caused by climate change. Upwelling brings low-oxygen, nutrient-rich water up to the surface, leading to plankton blooms and mass consumption …


Wayne E. Sabbe Arkansas Soil Fertility Studies 2025, Nathan A. Slaton Mar 2026

Wayne E. Sabbe Arkansas Soil Fertility Studies 2025, Nathan A. Slaton

Arkansas Agricultural Experiment Station Research Series

Rapid technological changes in crop management and production require that the research efforts be presented in an expeditious manner. The contributions of soil fertility and fertilizers are major production factors in all Arkansas crops. The studies described within will allow producers to compare their practices with the university’s research efforts. Additionally, soil-test data and fertilizer sales are presented to allow comparisons among years, crops, and other areas within Arkansas.


Comparison Of Analytical Techniques From The Extraction Of Bioactive Compounds From Kratom, Curry, Ginger, And Turmeric, Riley Bruno Mar 2026

Comparison Of Analytical Techniques From The Extraction Of Bioactive Compounds From Kratom, Curry, Ginger, And Turmeric, Riley Bruno

Honors Program: Senior Projects (Public)

Plants, herbs, and spices have been used as medicines for thousands of years. Early civilizations often attributed healing properties of plants to magical or divine forces. However, as chemistry and analytical technology advanced between the 16th and 18th centuries, scientists began to understand that bioactive compounds within the plants actually caused these effects. Today, natural products remain extremely important in drug discovery. As the number of newly developed synthetic drugs declines, there has been renewed interest in identifying biologically active molecules from plants. Bioactive molecules are a group of diverse chemical compounds that stimulate a response in living tissues. The …


Cultural Science Night, Jiyoon Yoon Feb 2026

Cultural Science Night, Jiyoon Yoon

Mavs Open Press Open Educational Resources - Archive

This book is to learn water and weather by integrating with other cultures. This textbook is organized around two interconnected components. The first component provides cultural knowledge of China, India, Korea, and Mexico. The second component focuses on culturally responsive science instruction created for the Cultural Science Night event, an occasion in which teachers present hands-on, culturally responsive science activities in collaboration with students.

If you need an accessibility accommodation or have questions about the use of this text, please contact Mavs Open Press.


Exosome Engineering For Blocking Gut Dysbiosis And Inducing Cell Death Mechanisms In Glioblastoma Multiforme, Ahalya Muraleedharan, Karthik Rangavajhula, Swapan K. Ray Feb 2026

Exosome Engineering For Blocking Gut Dysbiosis And Inducing Cell Death Mechanisms In Glioblastoma Multiforme, Ahalya Muraleedharan, Karthik Rangavajhula, Swapan K. Ray

Faculty Publications

Glioblastoma multiforme (GBM) is the most lethal primary brain tumor in adults. Emerging evidence endorses that gut dysbiosis contributes to GBM progression through the gut–brain axis (GBA), promoting inflammation and therapeutic resistance via abnormal short-chain fatty acid production and cytokine dysregulation. Exosomes, naturally occurring nanovesicles (30–150 nm), offer promising therapeutic potential due to their blood–brain barrier permeability, biocompatibility, and versatile cargo capacity. This review examines exosome engineering strategies for dual targeting: inhibiting alterations in gut microbiome and inducing regulated cell death mechanisms such as apoptosis and ferroptosis in GBM. We describe exosome engineering with detailed focus on cargo loading approaches …


Urban–Rural Disparities In Metabolic Risk Factors For Hypertension Among The Elderly In Indonesia, Susiana Nugraha, Puri Wulandari Feb 2026

Urban–Rural Disparities In Metabolic Risk Factors For Hypertension Among The Elderly In Indonesia, Susiana Nugraha, Puri Wulandari

Kesmas

Hypertension remains a major public health challenge among the elderly in low- and middle-income countries. This cross-sectional study examined demographic and metabolic factors associated with hypertension among the elderly living in urban and rural areas of West and Central Java Provinces, Indonesia. This study included 1,920 adults aged ≥60 years who had resided in the study areas for at least six months, were able to communicate effectively, and provided informed consent. Data were collected between March and August 2023 using stratified multistage random sampling, structured questionnaires, and biochemical measurements. Multivariable logistic regression revealed distinct patterns of association across settings. In …


Association Between Dietary Folate And Prostate Cancer Aggressiveness Among African Americans And European Americans, Lihchyun Joseph Su, Sarah O'Connor, Daniela Ramirez Aguilar, Minjae Lee, Harrison Wong, Hui-Yi Lin, Jeannette T. Bensen, James L. Mohler, Lenore Arab, Longgang Zhao, Ebonee N. Butler, Laura Farnan, Susan E. Steck Phd, Mph, Rd Feb 2026

Association Between Dietary Folate And Prostate Cancer Aggressiveness Among African Americans And European Americans, Lihchyun Joseph Su, Sarah O'Connor, Daniela Ramirez Aguilar, Minjae Lee, Harrison Wong, Hui-Yi Lin, Jeannette T. Bensen, James L. Mohler, Lenore Arab, Longgang Zhao, Ebonee N. Butler, Laura Farnan, Susan E. Steck Phd, Mph, Rd

Faculty Publications

Background: Despite the confirmed beneficial effects on preventing neural tube defects, concerns about high intakes of synthetic folate, or folic acid, in promoting cancer progression have been raised. This study evaluated the association between folate intake and prostate cancer (PCa) aggressiveness among African-American (AA) and European-American (EA) males. Methods: This study included 722 AA and 775 EA men with prostate cancer. Folate intake (dietary folate equivalent (DFE), synthetic folate, natural folate) was estimated using the National Cancer Institute Dietary History Questionnaire and detailed dietary supplement use questionnaire. Analyses included univariable comparisons of demographic and clinical characteristics of the two racial …


Influence Of Plasticizer Type On The Structure And Drug Release Characteristics Of Lm-Pectin Hydrogels, Banu Kocaağa, Fatma Seni̇ha Güner Feb 2026

Influence Of Plasticizer Type On The Structure And Drug Release Characteristics Of Lm-Pectin Hydrogels, Banu Kocaağa, Fatma Seni̇ha Güner

Turkish Journal of Chemistry

This study investigated the effects of different plasticizers—castor oil (CO), polyvinylpyrrolidone (PVP), and polyethylene glycol (PEG) with varying molecular weights (MWs)—on the structure and drug-release performance of low-methoxyl pectin (LM-pectin) hydrogels. Theophylline was used as a model drug to evaluate release behavior under physiologically relevant conditions. The incorporation of plasticizers modulated polymer–polymer interactions, swelling behavior, and thermal properties, thereby affecting drug-release kinetics. CO, a hydrophobic triglyceride, created microdomain-induced diffusion pathways; PVP, containing water-affinitive lactam units, facilitated moisture-driven plasticization; and PEG (MW 400/1000/1500), with hydroxyl-terminated chains, established hydrogen bonds with pectin. Structural analyses (FTIR and DSC) revealed that CO disrupted pectin …


Antioxidant Potential Of Sulfenimides In Waste Walnut Oil Biodiesel: Kinetic Stability, Phosphomolybdenum Activity, And Reducing Power Capacity, Nalan Türköz Karakullukçu, Hasan Yakan, Volkan Murat Yilmaz, Hali̇t Muğlu, Semi̇ha Yeni̇gün, Hali̇l Kütük Feb 2026

Antioxidant Potential Of Sulfenimides In Waste Walnut Oil Biodiesel: Kinetic Stability, Phosphomolybdenum Activity, And Reducing Power Capacity, Nalan Türköz Karakullukçu, Hasan Yakan, Volkan Murat Yilmaz, Hali̇t Muğlu, Semi̇ha Yeni̇gün, Hali̇l Kütük

Turkish Journal of Chemistry

This study investigated the influence of synthetic sulfenimides on biodiesel–diesel fuel blends. Three previously synthesized sulfenimide derivatives were structurally characterized using spectroscopic techniques. We evaluated their antioxidant properties through phosphomolybdenum activity and reducing power capacity assays. The tested fuel samples were designated as D100, B10D90, B10D90_AA (ascorbic acid), B10D90_3, B10D90_2, and B10D90_1. The effect of adding 2000 ppm of the additive was measured using an Oxifast instrument following the ASTM D7545 standard, and the results were compared to those of the chemical antioxidant ascorbic acid. Inhibition time values were derived from the oxidation stability results. The starting temperatures for crystallization …


Trends In Self-Reported Responses To Nutrition Facts Labels Before And After Nutrition Labeling Policy Implementation: A Comparison Of Adults In The United States And Mexico, Jim Thrasher Ph.D., Ma, Ms, Victor Vilalobos, Dai Fang, Alejandra Jáuregui, Alejandra Contreras-Manzano, Rachel Davis Ph.D., Lana Vanderlee, Christine M. White, Rachel B. Acton, James W. Hardin, Edward A. Frongillo Jr. Ph.D., Simón Barquera, David Hammond Feb 2026

Trends In Self-Reported Responses To Nutrition Facts Labels Before And After Nutrition Labeling Policy Implementation: A Comparison Of Adults In The United States And Mexico, Jim Thrasher Ph.D., Ma, Ms, Victor Vilalobos, Dai Fang, Alejandra Jáuregui, Alejandra Contreras-Manzano, Rachel Davis Ph.D., Lana Vanderlee, Christine M. White, Rachel B. Acton, James W. Hardin, Edward A. Frongillo Jr. Ph.D., Simón Barquera, David Hammond

Faculty Publications

Background

In 2020–2021, both Mexico and the United States implemented similar, newly formatted nutrition facts labels (NFLs). Mexico simultaneously implemented front-of-package warning labels (FoPWLs), which emphasize high amounts of less healthy nutrients described in NFLs (e.g., calories, sugar, salt, trans fat, and saturated fat) to enhance consumer understanding of nutrition information.

Objectives

To evaluate these policies by comparing pre- and postpolicy trends in self-reported responses to NFLs.

Methods

Annual surveys from the adult International Food Policy Study (2018–2023) were analyzed for Mexico (n = 24,832) and the United States (n = 25,464). Outcomes included reported ease of finding …


Survival On Image Regression With Application To Partially Functional Distributional Representation Of Physical Activity, Rahul Ghosal, Sunwoo Emma Cho, Marcos Matabuena Feb 2026

Survival On Image Regression With Application To Partially Functional Distributional Representation Of Physical Activity, Rahul Ghosal, Sunwoo Emma Cho, Marcos Matabuena

Faculty Publications

Technological advancements in wearable devices and medical imaging often lead to high-dimensional physiological signals in the form of images or surfaces. To address these data structures, we develop a novel survival on image regression model with a specific focus on partially functional distributional representation of wearable data. The existing approaches for functional data and survival outcomes have been primarily developed for uni-dimensional functional predictors. Drawing on recent developments in distributional data analysis, we model temporally varying distributional patterns of physical activity (PA) as a partially functional distributional predictor within a semiparametric Cox model framework. We use tensor product splines to …


Satellites, Urban Heat, And Environmental Justice: Community As The Bridge Between Analysis And Action, Joshua B. Fisher, Ambar Rivera, Ava Cison, Ashley Agatep, Kainani Tacazon, Sophia Spiegleman, Alison Mckenery, Rio E. Fisher, Reginald Archer, Jason A. Douglas Feb 2026

Satellites, Urban Heat, And Environmental Justice: Community As The Bridge Between Analysis And Action, Joshua B. Fisher, Ambar Rivera, Ava Cison, Ashley Agatep, Kainani Tacazon, Sophia Spiegleman, Alison Mckenery, Rio E. Fisher, Reginald Archer, Jason A. Douglas

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Heat waves are increasing in frequency, intensity, magnitude, and duration, causing a disproportionate impact on marginalized communities exposed to urban heat islands. Newly emerging spaceborne thermal sensing instruments, such as ECOSTRESS and Hydrosat, now have the capabilities to measure urban surface temperatures accurately at the block level (< 100 m) and with enough frequency to capture transient heat waves (daily to subweekly). Such data are critical for monitoring and informing policy and mitigation efforts, such as resurfacing, green space, cooling stations, and medical mobilization. These serve to advance environmental justice and reduce health risks—and deaths—among the most vulnerable: minority, low-income, elderly, those with physical- and mental-health preconditions, unhoused, children, and outdoor workers. While scientists have increasingly used satellite data to quantify urban heat islands and risks to communities, there remains a significant gap in action resulting from such analyses—a figurative and literal “valley of death.” Reviewing over 500 scientific publications, we identify a critical lack of engagement with the communities being analyzed (10.9%; n = 58); yet, community engagement is key to bridging such analysis with subsequent action. Here, we demonstrate how participatory community engagement directly with data and analysis leads to increased policy changes and mitigation efforts. Our framework has immediate implications for how scientists may augment their work and thought processes to achieve …


Molecular Detection Of Genes Encoded For Biofilm Formation In Bacteria Isolated From The Oral Cavity Of Patients, Tebarek Al-Taei, Ali A. Al-Hisnawi Feb 2026

Molecular Detection Of Genes Encoded For Biofilm Formation In Bacteria Isolated From The Oral Cavity Of Patients, Tebarek Al-Taei, Ali A. Al-Hisnawi

Karbala International Journal of Modern Science

Background: A biofilm is a collection of the microbial cells attached to the surface that are encased in a matrix of extracellular polymers. Biofilm formation creates a physical and chemical barrier that prevents antibiotics from reaching bacterial cells, resulting in treatment failure and reinfection. The present study aimed to investigate the biofilm formation in bacteria isolated from the oral cavity of patients.

Methods: In this study, 150 bacterial isolates were obtained from tooth and gum surface swabs of male and female patients of different ages who visited specialized centers and dental clinics in Babylon City after they were clinically diagnosed …


Pediatric Inflammatory Bowel Disease Tissue Classification From Pathology Slide Images: Detecting Phenotypes Using Computer Vision, Chloe Martin-King, Ali Nael, Louis Ehwerhemuepha, Blake Calvo, Quinn Gates, Jamie Janchoi, Elisa Ornelas, Melissa Perez, Andrea Venderby, John Miklavcic, Peter Chang, Aaron Sassoon, Brian Rubio, Ghislaine Barrigan, Kenneth Grant Feb 2026

Pediatric Inflammatory Bowel Disease Tissue Classification From Pathology Slide Images: Detecting Phenotypes Using Computer Vision, Chloe Martin-King, Ali Nael, Louis Ehwerhemuepha, Blake Calvo, Quinn Gates, Jamie Janchoi, Elisa Ornelas, Melissa Perez, Andrea Venderby, John Miklavcic, Peter Chang, Aaron Sassoon, Brian Rubio, Ghislaine Barrigan, Kenneth Grant

Food Science Faculty Articles and Research

Background and Aims

With the advent of computer vision algorithms, we hypothesize that histopathology images from endoscopic biopsies may be utilized for automated classification of histologic phenotypes, thus guiding Crohn’s disease and ulcerative colitis diagnosis and treatment. The aim of our study is to assess whether artificial intelligence can be used to improve pediatric inflammatory bowel disease outcomes by aiding pathologists with accurate detection of abnormal tissue sections.

Methods

Three two-dimensional (2D) convolutional neural networks with multiple instance learning were developed to classify histopathology tissue sections as normal vs abnormal and as containing active inflammation and/or chronic changes/architectural distortion.

Results …


Discovery Of Horsfieldia Macrothyrsa Bioactives With Cytotoxic Effects On Breast Cancer Cells Through In Vitro And Docking Analyses, Megawati Megawati, Akhmad Darmawan, Agus Budiawan Naro Putra, Kartika Dyah Palupi, Marissa Angelina, Ahmad Randy, Siska Andrina Kusumastuti, Faris Hermawan, Sumi Hudiyono Feb 2026

Discovery Of Horsfieldia Macrothyrsa Bioactives With Cytotoxic Effects On Breast Cancer Cells Through In Vitro And Docking Analyses, Megawati Megawati, Akhmad Darmawan, Agus Budiawan Naro Putra, Kartika Dyah Palupi, Marissa Angelina, Ahmad Randy, Siska Andrina Kusumastuti, Faris Hermawan, Sumi Hudiyono

Karbala International Journal of Modern Science

This study investigated the phytochemical constituents and biological activities of Horsfieldia macrothyrsa leaves to identify their bioactive compounds. Methanol extracts were fractionated using n-hexane and ethyl acetate, followed by silica gel column chromatography with a stepwise polarity gradient. From 100 g of powdered leaves, three major    compounds were successfully isolated from the ethyl acetate fraction: 1-(2,4,6-trihydroxyphenyl)dodecan-1-one (1), sesamin (2), and β-sitosterol (3). Their chemical structures were confirmed using UV, IR, LC–MS/MS, and NMR  spectroscopy. Biological activities of the fractions and isolates were evaluated through DPPH antioxidant assays, α-glucosidase inhibition for antidiabetic activity, MTT …


Early Detection Of Infectious Diseases: A Review Of Recent Advances In Pathogen Identification, Molecular Tools, And Metabolomics-Driven Biomarker Discovery, Patrica Ivy Agorsor, Michael O. Eze Feb 2026

Early Detection Of Infectious Diseases: A Review Of Recent Advances In Pathogen Identification, Molecular Tools, And Metabolomics-Driven Biomarker Discovery, Patrica Ivy Agorsor, Michael O. Eze

Chemistry Faculty Research & Creative Works

The recent COVID-19 pandemic has heightened public interest in noninvasive methods for early diagnosis of infectious diseases. In addition, various government agencies have implemented "infectious disease preparedness" to mitigate future outbreaks. This review highlights conventional and advanced methods for infectious disease diagnosis with an emphasis on emerging mass spectrometry methods. Conventional methods for pathogen identification, such as culture-based techniques and molecular methods, have limitations with respect to sensitivity, specificity, and turnaround time. Recent advances in high-resolution mass spectrometry have revolutionized the field of infectious disease biomarker discovery. These techniques enable the comprehensive profiling of metabolites in various biological samples, identification …


To Hold Or Sell Breeding Cattle In The Rangelands, Department Of Primary Industries And Regional Development, Western Australia Feb 2026

To Hold Or Sell Breeding Cattle In The Rangelands, Department Of Primary Industries And Regional Development, Western Australia

Animal production and livestock factsheets

In a dry season where feed, water and finances are limited, removing less productive animals as soon as possible is a good option. This will free up feed for more productive animals and help preserve ground cover.

This page provides some of the information and a process for making decisions about holding or selling breeding cattle.


Variation In Food Web Reliance On Green And Brown Energy Pathways Across Ecosystem Gradients, James W. Sturges, W. Ryan James, Ryan J. Rezek, Rolando O. Santos, Mack White, Gina A. Badlowski, Shakira Trabelsi, Jordan Massie, Justin S. Lesser, Joel C. Trexler, James Nelson, Jennifer S. Rehage Feb 2026

Variation In Food Web Reliance On Green And Brown Energy Pathways Across Ecosystem Gradients, James W. Sturges, W. Ryan James, Ryan J. Rezek, Rolando O. Santos, Mack White, Gina A. Badlowski, Shakira Trabelsi, Jordan Massie, Justin S. Lesser, Joel C. Trexler, James Nelson, Jennifer S. Rehage

Marine Science

Aquatic food webs typically include highly coupled fast, ‘green’ energy pathways driven by algae or phytoplankton and slower, ‘brown’ energy channels driven by detritus and terrestrial plants. Quantifying how much energy biological communities obtain from each of these pathways is essential, particularly across multiple interconnected food webs over large areas, because energy dynamics are known to influence ecosystem structure and function. Despite their importance, few studies track variance in energy channel contributions to food webs across interconnected habitats during distinct hydrologic seasons. In this study, we used tri-isotope Bayesian mixing models to quantify seasonal contributions of energy pathways to consumers …


Demographic And Other Correlates Of Non-Prescription Drug Use Among College Students During The Covid-19 Pandemic, Subi Gandhi, Sidketa Fofana, Md Rafiul Islam, Tamer Oraby Feb 2026

Demographic And Other Correlates Of Non-Prescription Drug Use Among College Students During The Covid-19 Pandemic, Subi Gandhi, Sidketa Fofana, Md Rafiul Islam, Tamer Oraby

School of Mathematical & Statistical Sciences Faculty Publications

Background and objectives: Substance use among college students in the U.S. remains a pressing concern and may have intensified during the COVID-19 pandemic due to increased stress, uncertainty, and academic disruptions. This study investigates the relationship between non-prescription drug use and various demographic, mental health, and behavioral factors among college students during the pandemic's early stages.

Methods: Data were collected through online and in-person surveys in the summer semester of 2021. Behavioral health was assessed using validated instruments: the Patient Health Questionnaire-9 (PHQ-9) for depression and the Drug Abuse Screening Test-20 (DAST-20) for substance use. Demographic and behavioral variables were …


Evaluation Of Large Language Models As Decision Support Tools For Head And Neck Cancer Management: A Blinded Multidisciplinary Simulation Study, Sholem Hack, Ron J. Karni, Antonino Maniaci, Christopher E. Fundakowski, Luca Castellani, Fabiola Incandela, Remo Accorona, Miguel Mayo-Yanez, Martina Violati, Lorenzo Giannini, Niccolo' Mevio, Alberto Maria Saibene Jan 2026

Evaluation Of Large Language Models As Decision Support Tools For Head And Neck Cancer Management: A Blinded Multidisciplinary Simulation Study, Sholem Hack, Ron J. Karni, Antonino Maniaci, Christopher E. Fundakowski, Luca Castellani, Fabiola Incandela, Remo Accorona, Miguel Mayo-Yanez, Martina Violati, Lorenzo Giannini, Niccolo' Mevio, Alberto Maria Saibene

Department of Otolaryngology - Head and Neck Surgery Faculty Papers

BACKGROUND: The management of head and neck cancer relies on multidisciplinary expertise; however, access to tumor boards remains variable. Large language models (LLMs) may support guideline-based decision-making, although performance in complex oncologic scenarios is not well defined.

METHODS: Fourteen synthetic cases based on real tumor board encounters were evaluated. Five blinded comparator arms produced recommendations: a human expert, Non-RAG-GPT-4, Non-RAG-GPT-5, RAG-GPT-4, and RAG-GPT-5. Eight head and neck oncologic surgeons scored each recommendation for appropriateness, clarity, specificity, and feasibility using 5-point Likert scales. Paired permutation testing and inter-rater reliability were assessed.

RESULTS: LLM outputs showed close alignment with expert recommendations. RAG-based …


Handling Missing Data In Copd Research, Chia-Ying Chiu Jan 2026

Handling Missing Data In Copd Research, Chia-Ying Chiu

ETDs from 2020-2029

Chronic Obstructive Pulmonary Disease (COPD) remains a major global health concern and one of the leading causes of death in the United States, affecting approximately 4.6% of adults and reaching a prevalence of 9.4% in Alabama according to 2024 National Health Interview Survey. The disease imposes a substantial burden on quality of life and healthcare costs and contributes to increased disability-adjusted life years and years of life lost, as highlighted by the 2022 Lancet Commission report. Despite its im-pact, COPD is frequently diagnosed only after irreversible lung damage has occurred, largely due to under-recognized symptoms and limited diagnostic tools. Early …


Development Of Salinomycin Analogs As Potential Anti-Cancer Agents, Pavan Goud Juluri Jan 2026

Development Of Salinomycin Analogs As Potential Anti-Cancer Agents, Pavan Goud Juluri

Theses and Dissertations

Salinomycin, a poly-ionophore antibiotic originally isolated from Streptomyces albus, exhibits antimicrobial activity against Gram-positive bacteria. Over the years Salinomycin has been studied in the effects it has on cancer, specifically cancer stem cells. Poly(ADP-ribose) polymerase (PARP) is an enzyme involved in DNA repair. Inhibiting PARP has been explored as a strategy in cancer treatment, particularly in cancers with defective DNA repair mechanisms, such as those with BRCA mutations. The benzo-thiazoles, and -imidazoles are identified as inhibitor scaffolds, which compete with nicotinamide in the binding pocket of human poly- and mono-ADP-ribosylating enzymes. Benzothiazole, and benzimidazole based compounds particularly with modification at …


Correlation Analysis Of Factors Associated With Students’ Numeracy Skills Using Decision Tree Algorithms, Yenita Roza, Arisman Adnan, Zul Indra, Tuti Alawiyah Jan 2026

Correlation Analysis Of Factors Associated With Students’ Numeracy Skills Using Decision Tree Algorithms, Yenita Roza, Arisman Adnan, Zul Indra, Tuti Alawiyah

Numeracy

Numeracy is a critical competency for academic and everyday functioning. This study investigates the key factors associated with students’ numeracy skills by employing decision tree algorithms as a data mining technique. The dataset used in this study is educational assessment data from Indonesia. Utilizing a dataset comprising 6,953 entries and 60 variables from Education Report, the research adopts an exploratory approach involving data preprocessing, exploratory data analysis, and decision tree model construction. The findings reveal that students’ literacy skills serve as the most dominant predictor of numeracy proficiency, emerging as the root node in the decision tree structure. Additional associated …


Lead Levels In Fingernails Of Hemodialysis Patients And Healthy Individuals In Karbala, Iraq: A Biomonitoring Study Using Icp Oes, Baker A. Joda, Rusul Jaafar, Rana Hameed, Hiba Sadeq Alheloo, Sadeq Jaafar Hasan Dwenee Jan 2026

Lead Levels In Fingernails Of Hemodialysis Patients And Healthy Individuals In Karbala, Iraq: A Biomonitoring Study Using Icp Oes, Baker A. Joda, Rusul Jaafar, Rana Hameed, Hiba Sadeq Alheloo, Sadeq Jaafar Hasan Dwenee

Karbala International Journal of Modern Science

The use of non-invasive media to evaluate the association between trace elements and diseases has spread in recent centuries. Fingernail samples were collected from 103 individuals, including both healthy participants and those undergoing hemodialysis, residing in Karbala, Iraq, and ranging in age from 21 to 75 years. The concentrations of lead were determined using an Inductively Coupled Plasma Optical Emission Spectrometry (ICP OES). Statistical analyses using F-tests and two-tailed t-tests were conducted to examine the effects of health status, gender, smoking status, and their interactions on lead levels in washed fingernails. The concentrations of Pb in washed fingernails of healthy …


Dietary Inflammatory Index And Risk Of Colorectal Cancer In Japanese Men, Ayaka Kotemori, Kumiko Kito, Motoki Iwasaki, Taiki Yamaji, James Hébert Scd, Junko Ishihara, Manami Inoue, Shoichiro Tsugane, Norie Sawada On The Behalf Of Jphc Study Group Jan 2026

Dietary Inflammatory Index And Risk Of Colorectal Cancer In Japanese Men, Ayaka Kotemori, Kumiko Kito, Motoki Iwasaki, Taiki Yamaji, James Hébert Scd, Junko Ishihara, Manami Inoue, Shoichiro Tsugane, Norie Sawada On The Behalf Of Jphc Study Group

Faculty Publications

Background/Objectives: Unhealthy lifestyles lead to chronic low-grade inflammation, increasing the risk of colorectal cancer. Few studies in East Asia have examined the association between the dietary inflammation potential and colorectal cancer incidence. Therefore, we aimed to investigate this association further in the Japanese population. Methods: This study included 38,807 men aged 45–74 years who participated in the Japan Public Health Center-based prospective study (JPHC Study). The energy-adjusted dietary inflammatory index (E-DII) was derived from a food frequency questionnaire. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox proportional hazards regression models. Differences in risk due to a …


Ultrasonic Extraction-Based Analysis Of Persistent Organic Pollutants In Blubber From False Killer Whales, Michael O. Eze, Eva Borras, Mitchell M. Mccartney, Don R. Bergfelt, Kristi L. West, Sarah E. Hooper, Cristina E. Davis Jan 2026

Ultrasonic Extraction-Based Analysis Of Persistent Organic Pollutants In Blubber From False Killer Whales, Michael O. Eze, Eva Borras, Mitchell M. Mccartney, Don R. Bergfelt, Kristi L. West, Sarah E. Hooper, Cristina E. Davis

Chemistry Faculty Research & Creative Works

In view of the toxic effects of persistent organic pollutants (POPs), fast and effective assessment of their concentrations in marine mammals is important for understanding individual and population-level health impacts. This study developed an ultrasonic-based method that is less time-consuming, uses minimal solvent, and thus is more sustainable than the gold standard Soxhlet method for accurate analysis of organochlorine pesticides (OCs), polychlorinated biphenyls (PCBs), and benzene hexachlorides (BHC) in false killer whale blubber. This method was developed by comparing concentrations of POPs obtained using the traditional Soxhlet and novel ultrasonic extraction methods using blubber from false killer whales (n = …


Natural Protective Mechanisms Of Cucumis Callosus Leaves In Escherichia Species-Induced Urinary Tract Infection: An Integrated In Silico And In Vivo Study, Meenal Sahu, Tripti Paliwal, Radhika Joshi, Arya Kuhu Vishwapriya, Namita Misra, Smita Jain, Gautam Singhvi, Gulshan Kumar, Devesh U. Kapoor, Dipjyoti Chakraborty, Swapnil Sharma Jan 2026

Natural Protective Mechanisms Of Cucumis Callosus Leaves In Escherichia Species-Induced Urinary Tract Infection: An Integrated In Silico And In Vivo Study, Meenal Sahu, Tripti Paliwal, Radhika Joshi, Arya Kuhu Vishwapriya, Namita Misra, Smita Jain, Gautam Singhvi, Gulshan Kumar, Devesh U. Kapoor, Dipjyoti Chakraborty, Swapnil Sharma

Michigan Tech Publications

Leaves of Cucumis callosus, traditionally employed in Ayurvedic medicine for the treatment of urinary disorders, were investigated in depth for their therapeutic potential against bacterially induced urinary tract infection (UTI) for the first time. The present work is the first to explore the antibacterial activity of C. callosus leaf fractions with an integrative in silico, in vitro, and in vivo approach. Through bioassay-guided fractionation, the chloroform fraction (F1) was identified as the most active, exhibiting potent activity against Uropathogenic Escherichia spp. species. Liquid chromatography–mass spectrometry (LC-MS) analysis of F1 revealed the presence of bioactive compounds, including stigmasterol, 1,2,3,4-tetrahydroisoquinoline, lactose, hydroxy(mesityl)acetic …


Modulation Of Hypothalamic–Limbic Circuits Regulating Appetite In Response To Health Lifestyle In Obese Adults, Nour Shakir Rezaieg, Muthanna M. Awad Jan 2026

Modulation Of Hypothalamic–Limbic Circuits Regulating Appetite In Response To Health Lifestyle In Obese Adults, Nour Shakir Rezaieg, Muthanna M. Awad

Karbala International Journal of Modern Science

Background: Overeating leads to obesity a low-grade inflammatory disease. In this context, aguati-related neuropeptide (AgRP) and ghrelin are pivotal players in appetite regulation, while chemerin is an adipose tissue-secreted adipokine that contributes to low-grade inflammation associated with obesity. Objective: This study used a healthy lifestyle program designed for each obese participant to identify diet-related neuro-hormonal changes in appetite regulation. Design, Setting, and Participants: This a longitudinal quasi-experimental controlled study was conducted from 1st December 2024, to 30th July 2025, at University of Anbar. The sample included 100 participants, 50 obese (weight between 100–140 kg) and 50 healthy participants …