Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- University of Nebraska - Lincoln (2445)
- Singapore Management University (2302)
- Brigham Young University (1907)
- TÜBİTAK (1302)
- Wright State University (1051)
-
- Old Dominion University (968)
- Missouri University of Science and Technology (868)
- University of Kentucky (787)
- Utah State University (766)
- Portland State University (746)
- University of Nevada, Las Vegas (714)
- Edith Cowan University (655)
- University of South Florida (648)
- Montana Tech Library (600)
- City University of New York (CUNY) (597)
- Technological University Dublin (566)
- University of Central Florida (555)
- Air Force Institute of Technology (538)
- Louisiana State University (526)
- Embry-Riddle Aeronautical University (490)
- University of Arkansas, Fayetteville (479)
- Nova Southeastern University (459)
- Chulalongkorn University (456)
- University of Texas Rio Grande Valley (440)
- San Jose State University (374)
- California Polytechnic State University, San Luis Obispo (369)
- Western Kentucky University (367)
- Claremont Colleges (349)
- Purdue University (348)
- New Jersey Institute of Technology (345)
- Keyword
-
- Machine learning (527)
- Artificial intelligence (362)
- Sustainability (333)
- Social media (290)
- Climate change (274)
-
- Machine Learning (265)
- Cybersecurity (241)
- Deep learning (230)
- Education (229)
- Computer Science (205)
- Security (205)
- Chemistry (193)
- Mathematics (188)
- Privacy (183)
- Twitter (179)
- Artificial Intelligence (175)
- Priority Soils (172)
- Nanoparticles (168)
- Natural language processing (167)
- Computer science (160)
- COVID-19 (158)
- Statistics (144)
- Technology (142)
- United States (137)
- Environment (134)
- Groundwater (128)
- AI (122)
- Applied sciences (121)
- Water quality (119)
- Western Kentucky University (110)
- Publication Year
- Publication
-
- Theses and Dissertations (3160)
- Research Collection School Of Computing and Information Systems (2051)
- Electronic Theses and Dissertations (747)
- Turkish Journal of Chemistry (642)
- Silver Bow Creek/Butte Area Superfund Site (561)
-
- Kno.e.sis Publications (540)
- Dissertations (482)
- Faculty Publications (443)
- Chulalongkorn University Theses and Dissertations (Chula ETD) (395)
- USF Tampa Graduate Theses and Dissertations (378)
- Turkish Journal of Electrical Engineering and Computer Sciences (349)
- Walden Dissertations and Doctoral Studies (329)
- Masters Theses (326)
- Theses (315)
- LSU New Orleans Theses and Dissertations (312)
- LSU Doctoral Dissertations (300)
- Articles (289)
- UNLV Theses, Dissertations, Professional Papers, and Capstones (269)
- Open Access Theses & Dissertations (265)
- Journal of Electrochemistry (264)
- All Works (262)
- CCAC Theses and Dissertations (245)
- Coal Geology & Exploration (237)
- Graduate Theses and Dissertations (230)
- Dissertations and Theses (226)
- Honors Theses (217)
- Master's Projects (210)
- Publications (208)
- IGC Proceedings (1977-2023) (206)
- Doctoral Dissertations (197)
- Publication Type
Articles 301 - 330 of 40779
Full-Text Articles in Entire DC Network
Experimental Results With Various Herbicides In Established Alfalfa, Taib Saric, Refik Numic
Experimental Results With Various Herbicides In Established Alfalfa, Taib Saric, Refik Numic
IGC Proceedings (1977-2023)
5-year experiments with herbicides were run in the mixture of alfalfa, red clover, timothy grass, and Italian ryegrass. On untreated plots, in the 5-year average 72 weed plants were found per 1 m2 , belonging to 66 weed species. Among them most numerous were: Stellaria media, Veronica agrestis, Poa annua, Lamium purpureum,Taraxacum officinale, and Capsella bursa pastoris. The most efficient herbicide was Etazin, killing 88 % of weeds. None of the applied herbicides controlled perennial weeds. Etazin was tolerated by alfalfa, but was toxic to the other three crops. Kerb, Kerb-Mix, and Multitok were toxic to sown grasses, while …
Recommended Values For Dimensioning And Designing Sprinkler Irrigation In Industrialized Forage Plant ProducTion In The Gdr, Klaus Schwarz, Dieter Roth
Recommended Values For Dimensioning And Designing Sprinkler Irrigation In Industrialized Forage Plant ProducTion In The Gdr, Klaus Schwarz, Dieter Roth
IGC Proceedings (1977-2023)
With the transition to industrialized crop and animal production in the GDR, sprinkler irrigation of field forage plants and grassland, above all with sewage water and clean water +slurry mixtures, is becoming more and more important. It gets increasingly concentrated on field grass and grass/clover stands. The supplemental water requirement is 210 to 270 mm/ year in case of clean-water sprinkling and up to 400 mm/year if sewage water is used. The hydro-modulus of the irrigation plants is between 1.2 and 1.6 m3 /h/ha, depending on the simultaneity factor. In order to attain the required water quantity per unit of …
Transformative Climate Change Mitigation And Adaptation Policy Analysis In Medan City, Citra Tatius, Mega Anggraeni, Wiwandari Handayani, Rukuh Setiadi
Transformative Climate Change Mitigation And Adaptation Policy Analysis In Medan City, Citra Tatius, Mega Anggraeni, Wiwandari Handayani, Rukuh Setiadi
Cities and Urban Development Journal
Background: Climate change is not only a global challenge but also a strategic issue of development in Indonesia. The Medan City Government has implemented various mitigation and adaptation efforts, yet it continues to produce greenhouse gas emissions and is exposed to climate change impacts. A transformative approach in mitigation and adaptation is needed to enable systemic change to comprehensively address climate change from its root causes.
Aims: This paper aims to elaborate on the extent to which mitigation and adaptation policies in Medan City can fulfill the principles of transformative climate actions.
Methods: Data collection for climate profiles and mitigation …
Final Unreclaimed Sites Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc.
Final Unreclaimed Sites Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc.
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
2026 Final Unreclaimed Sites Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc.
2026 Final Unreclaimed Sites Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc.
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Final Insufficiently Reclaimed Sites Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc.
Final Insufficiently Reclaimed Sites Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc.
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Public Responses About Air Quality In The World’S Ten Most Populous Countries, Noah Lim, Alessandro Del Ponte, Lina Ang, Wei Jie Seow
Public Responses About Air Quality In The World’S Ten Most Populous Countries, Noah Lim, Alessandro Del Ponte, Lina Ang, Wei Jie Seow
Political Science Faculty Articles and Research
Understanding how people view and react to outdoor air quality is crucial to effectively managing and responding to air pollution, which is a major threat to global public health. Using a quota sample of 10,618 respondents from 1,372 localities across the world’s ten most populous countries (Bangladesh, Brazil, China, Indonesia, India, Mexico, Nigeria, Pakistan, Russia, and the United States), we assessed the association between exposure to fine particulate matter with diameter ≤ 2.5 micrometers (PM2.5) and people’s knowledge, attitudes, perceptions, practices, and concern about air quality. Overall, we find an inverse association between air pollution exposure and knowledge about air …
Governance, Culture, And Law: The Expanding Scope Of Environmental Science And Sustainable Development Research, Ahyaudin Sodri, Herdis Herdiansyah
Governance, Culture, And Law: The Expanding Scope Of Environmental Science And Sustainable Development Research, Ahyaudin Sodri, Herdis Herdiansyah
Journal of Environmental Science and Sustainable Development
Environmental science emerged as a discipline based on physical measurements, such as soil pollutant levels (Ailijiang et al., 2022), ecological restoration (Yue et al., 2026), city surface temperature (Shafizadeh-Moghadam et al., 2025), and microbial density in air samples (Hayleeyesus & Manaye, 2014). However, its objects of study increasingly extend beyond the confines of the laboratory. Questions that were once sufficiently answered with measurement data now require answers through draft laws, Constitutional Court decisions, financial reports of mining companies, and even traditional ritual discourses governing community access to forests. In other words, environmental …
Attention-Based Ensemble Deep Learning Model For Arabic And English Fake News Classification, Ameer Alhaq Alshamery
Attention-Based Ensemble Deep Learning Model For Arabic And English Fake News Classification, Ameer Alhaq Alshamery
Journal of Intelligent Informatics, Networking, and Cybersecurity
It is difficult to classify articles as fake news since one article may consist of true facts with only some statements being fake. Moreover, classification becomes complicated for the Arabic language owing to its morphology and several ways of spelling, as well as the lack of well-classified and marked data sets. This paper presents an Ensemble Deep Learning Model (EDLM) used for Arabic and English fake news classification. The EDLM consists of CNN, Bi-LSTM with attention, and Bi-GRU with attention networks. Each of them produces one probability of the article, which is then summed up to a final probability via …
Bridging The Gap In Science Research: Preparing Students For College- Level Research In The Sciences, Victoria Helwig, Yaoguang Li
Bridging The Gap In Science Research: Preparing Students For College- Level Research In The Sciences, Victoria Helwig, Yaoguang Li
UConn Library Presentations
Many first-year students enter college unprepared to fully engage with scientific literature and academic library resources. Drawing on experiences from academic librarians working with STEM students, this session explores common gaps in science research skills, including navigating databases, identifying scholarly sources, and understanding the structure of scientific literature. Participants will be introduced to practical strategies and classroom-ready activities to better prepare students for college-level research. Discussion questions: What science research skills do students struggle with most when entering college? How can high school instruction better support these skills? Where can librarians and educators collaborate to support student success?
Gradients Of Abandonment, William Tatman
Gradients Of Abandonment, William Tatman
Geography ETDs
As urban-rural disparities drive depopulation in rural areas worldwide, local strategies emerge as pathways for resilience. Research on Ojika, a Japanese island that has lost 75% of its population since the 1960s, reveals an Abandonment Gradient: a nuanced pattern of disuse adapted to modern polycrises. Extending the concept of "lying fallow" to homes and infrastructure, this thesis focuses on abandonment practices that reflect complex realities of labor, capital, and climate uncertainty. Rather than viewing depopulating communities as passive victims of out-migration, this paper argues they are critical sites for generating crisis response. Communally crafted attitudes toward unused space and more-than-human …
Timelines Over Tokens: Summarization, Prompting, And Explainable Fine-Tuning For User-Level Suicide Risk Detection, Aditya Tekale
Timelines Over Tokens: Summarization, Prompting, And Explainable Fine-Tuning For User-Level Suicide Risk Detection, Aditya Tekale
Master's Theses
This research presents a two-stage pipeline for user-level suicide risk detection from Reddit: first, inference-only prompting with summarization; second, fine-tuned encoder classification with explainability and expert validation. The data are user-level: each of the 500 C-SSRS Reddit items is one user’s chronologically concatenated posts and comments (a user timeline), annotated by psychiatrists. Stage one: six prompting strategies zero-shot, few-shot, chain-of-thought, tree-of-thought, least-to-most, and self-consistency are evaluated across six LLMs on multi-class and binary formulations; simple zero-shot achieves the highest balanced accuracy (0.53 multi-class). Error analysis shows longer inputs associate with misclassification (p = 0.002); domain-specific summarization (timelines >2,000 tokens) reduces …
Dynamic Reconstruction Engineering Of Anti-Corrosion Ni-Based Anodes For Alkaline Seawater Electrolysis, Yi-Gang Zhang, Wen-Wen Xu, Tian-Yu Zhang, Zhi-Yi Lu
Dynamic Reconstruction Engineering Of Anti-Corrosion Ni-Based Anodes For Alkaline Seawater Electrolysis, Yi-Gang Zhang, Wen-Wen Xu, Tian-Yu Zhang, Zhi-Yi Lu
Journal of Electrochemistry
Green hydrogen production via alkaline seawater electrolysis offers an environmentally sustainable and potentially cost-effective route to address both energy and climate challenges. Achieving long-term anode stability under complex ionic environments and industrial current densities remains a central bottleneck. Specifically, Ni-based anodes exhibit intense surface reconstruction during the oxygen evolution reaction, necessitating dynamic anti-corrosion strategies. This mini review systematically summarizes reconstruction engineering approaches to develop anti-corrosion Ni-based anodes of alkaline seawater electrolysis across increasingly complex ionic environments from simulated seawater to real seawater: (i) Cl– dominated; (ii) Cl– with co-existing oxyanions, and (iii) Cl– with co-existing Br– …
Preparation And Performance Study Of In-Situ Self-Assembled Biphasic Smmn2O5-Nimn2O4 Composite Cathode, Neng-Chu Xia, Yu Zhou, Qin Wang, Jia-You Zhang, Chun Yu, Yang Zhang, Wan-Bing Guan, Jian-Xin Wang
Preparation And Performance Study Of In-Situ Self-Assembled Biphasic Smmn2O5-Nimn2O4 Composite Cathode, Neng-Chu Xia, Yu Zhou, Qin Wang, Jia-You Zhang, Chun Yu, Yang Zhang, Wan-Bing Guan, Jian-Xin Wang
Journal of Electrochemistry
Mullite-structured oxides exhibit excellent oxygen reduction reaction activity, possess a low thermal expansion coefficient due to their unique crystal structure, and can eliminate the need for a barrier layer and simplify the preparation process as they contain no alkaline earth elements. Thus, they hold great promise as novel cathode materials for solid oxide fuel cells. In this work, a mullite-spinel-structured SmMn2O5-NiMn2O4 (SMO-NMO) composite cathode was one-step synthesized via a solid-liquid composite route, and its in-situ self-assembly enabled good compatibility with the electrolyte without any barrier layer. Characterization results showed that the SMO:NMO = …
Mapping And Modeling Threat-Evoked Brain States After Early Life Adversity, Taylor W. Uselman
Mapping And Modeling Threat-Evoked Brain States After Early Life Adversity, Taylor W. Uselman
Biomedical Sciences ETDs
Early life adversity (ELA) increases lifelong neuropsychiatric vulnerability. Yet how ELA reorganizes brain-wide activity and circuit coordination across later experience remains unclear. This dissertation tests the hypothesis that ELA alters adult brain-wide activity and responses to threat through disrupted coordination among neural systems that regulate emotional experience, including prefrontal-limbic and monoaminergic systems. Longitudinal manganese-enhanced MRI of adult mice exposed to standard or fragmented early care, combined with computational processing and statistical modeling, quantified brain states before, during, and long after innate predator threat. These studies established that acute threat evokes large-scale, distributed brain activity that evolves over time. ELA potentiates …
Surveyception: An Exploration Of Deceptive Survey Forms, Muhammad Danish
Surveyception: An Exploration Of Deceptive Survey Forms, Muhammad Danish
Computer Science ETDs
Survey platforms such as Google Forms and Microsoft Forms are widely used for feedback, data collection, and engagement, but scammers increasingly exploit them to distribute phishing and deceptive attacks. This thesis presents a large-scale study of survey-form abuse across ten major providers. We collected 140,000 forms from three sources: public posts on X, search-engine results, and web pages from the top 10 million DomCop-ranked domains. Using automated filtering and manual qualitative review, we identified 2,645 forms requesting sensitive information and classified 566 as scams. These forms used techniques including phishing, private-secret theft, account and personal-data harvesting, financial deception, and psychological …
Final 2022 Unreclaimed Sites Sampling: Ur-07 Site Evaluation Summary Report, Pioneer Technical Services, Inc.
Final 2022 Unreclaimed Sites Sampling: Ur-07 Site Evaluation Summary Report, Pioneer Technical Services, Inc.
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Understanding The Long-Run Effect Of Historical Redlining Practices, Yujian Lu
Understanding The Long-Run Effect Of Historical Redlining Practices, Yujian Lu
Geography ETDs
Historical redlining practices initiated by Home Owners’ Loan Corporation (HOLC) in the 1930s have produced enduring persistent socioeconomic and environmental disparities in U.S. cities. This dissertation examines their long-term impacts on social vulnerability, urban flood risk, along with public discourse about redlining practices. Results indicate that neighborhoods with HOLC grade A (greenlined) exhibit the lowest overall social vulnerability, while those graded D (redlined) face the highest across U.S. cities. In Chicago, associations between redlining practices and flood risk disparities are stronger than in Los Angeles, reflecting place-specific characteristics among environmental, socioeconomic, and demographic factors shaping flood risk disparities in long …
Non-Traditional Rare-Earth-Doped Oxide Glass As A Gain Medium, Jared S. Tolliver
Non-Traditional Rare-Earth-Doped Oxide Glass As A Gain Medium, Jared S. Tolliver
Optical Science and Engineering ETDs
There is a need for mid-infrared(MIR) lasers in defense, medical, and environmental monitoring. A large part of this technological development is the study of gain media. One class of materials of special interest is glasses with a low maximum phonon energy. These have the fiberization and broad spectral features of glass, whereas glasses with high maximum phonon energy exhibit higher rates of multi-phonon relaxation and can be opaque in the MIR, both of which are detrimental to laser operation. Recent advances in container-less processing have allowed for the study of new glasses that aren’t possible with conventional fabrication techniques. One …
Butte Priority Soils Operable Unit Final 2022 Unreclaimed Sites Sampling: Ur-27 Site Evaluation Summary Report, Pioneer Technical Services, Inc.
Butte Priority Soils Operable Unit Final 2022 Unreclaimed Sites Sampling: Ur-27 Site Evaluation Summary Report, Pioneer Technical Services, Inc.
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Towards Intelligent Iot-Ndn Security: Ai-Driven Pit Attack Detection And Cache Attack Analysis, Sura Haidar Ali, Alaa Shawqi Jaber
Towards Intelligent Iot-Ndn Security: Ai-Driven Pit Attack Detection And Cache Attack Analysis, Sura Haidar Ali, Alaa Shawqi Jaber
Journal of Intelligent Informatics, Networking, and Cybersecurity
Beginning with Named Data Networking (NDN), an early form of information-centric networks, the paradigm of how data is transmitted over a network was changed through the use of ``content-based'' communication instead of ``host-based'', while creating native caching at intermediate points along the path to each destination, and improving upon the security of all previous paradigms. NDN contains many inherent benefits such as caching, security, etc., but like any other paradigm, NDN creates new types of vulnerabilities, particularly within some of the key elements of this paradigm; namely the Content Store (CS), Pending Interest Table (PIT), and the Forwarding Information Base …
Stop Blaming My Users: Illumination Of The Technocentric Mythos Bias, Ervin H. Frenzel, Richard Lightcap
Stop Blaming My Users: Illumination Of The Technocentric Mythos Bias, Ervin H. Frenzel, Richard Lightcap
Journal of Cybersecurity Education, Research and Practice
Abstract -This conceptual essay addresses the need for systemic and systematic transdisciplinary analytical techniques within cybersecurity and technical security. This conceptual essay is contingent upon recognition that cybersecurity is not simply technical in nature, it does not need an adversary, and more importantly it is based upon systems engineering and systems thinking. The essay contributes a socio-technical attribution chain and field-specific ontology/taxonomy which distinguish user-triggered events from root causes, latent conditions, technical debt, validation failures, governance failures, and attribution bias before assigning responsibility to end users. It systematically defines an ontology inclusive of developer technical debt, organizational debt arising from …
Superresolution Spectroscopy Of Atomically Thin Semiconductors And Moiré Heterostructures, Chien-Chu (Charity) Wei
Superresolution Spectroscopy Of Atomically Thin Semiconductors And Moiré Heterostructures, Chien-Chu (Charity) Wei
Master's Theses
Atomically thin semiconductors and moir’e heterostructures provide an important platform for studying quantum phenomena shaped by reduced dimensionality, interlayer coupling, strain, and local structure. In MoS2, the transition from bulk to monolayer form changes the material from an indirect to a direct band gap, while stacked and strain-engineered systems can produce spatially varying moir’e potentials on nanometer length scales. Because these effects are highly localized, conventional far-field optical spectroscopy is often limited in its ability to resolve them directly. This thesis explores superresolution vibrational spectroscopy as a route toward probing local behavior in atomically thin semiconductors and moir’e heterostructures. Far-field …
Sand Tank Experiments On The Seepage And Water Pressure Distribution During Single-Well Dewatering At The Bottom Of A Confined Aquifer, Wang Wenxue, Zhang Mengying, Li Yang, Fang Yuan, Zhao Shuli, Shen Mengjun
Sand Tank Experiments On The Seepage And Water Pressure Distribution During Single-Well Dewatering At The Bottom Of A Confined Aquifer, Wang Wenxue, Zhang Mengying, Li Yang, Fang Yuan, Zhao Shuli, Shen Mengjun
Coal Geology & Exploration
Background Depressurization through dewatering using inclined wells arranged at the aquifer bottom represents a crucial technical approach to the prevention and control of water-sand inrush disasters during coal mining beneath aquifers. However, the mechanisms underlying seepage-pressure interactions and water-preserved depressurization remain poorly understood. Methods Based on the water-yield properties of confined aquifers and the distribution characteristics of inclined wells for dewatering, this study developed a fan-shaped sand tank experimental system for simulating dewatering and seepage from confined aquifers. Using the experimental system, this study carried out seepage experiments using a partially penetrating well at the bottom of a confined aquifer …
Numerical Simulations And Dispersion Analysis Of 3d In-Seam Waves Based On Finite Difference Method On Curvilinear Grids, Liu Dan, Ren Zhiming
Numerical Simulations And Dispersion Analysis Of 3d In-Seam Waves Based On Finite Difference Method On Curvilinear Grids, Liu Dan, Ren Zhiming
Coal Geology & Exploration
Background With the comprehensive advancement in intelligent coal mine construction, creating high-precision, transparent geological models of coal seams and their surrounding strata has emerged as a prerequisite for intelligent coal mining. The accurate identification of concealed geological anomalies, such as folds and faults, within coal seams represents a key challenge in safe coal mining. In-seam seismic exploration has become an important approach to detecting underground concealed structures owing to its advantages, including a considerable detection distance along coal seams, high precision, pronounced frequency dispersion effects, and facilitating the identification of waveform signatures. However, conventional methods for seam wave simulation are …
Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Draft Final Unreclaimed Sites: Ur-27 Site Evaluation Summary Report (Sesr), Molly Roby
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Re: Conditional Approval Letter For The Draft Final 2024 Unreclaimed Sites Sampling: Ur-21 Site Evaluation Summary Report, Molly Roby
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Revised Draft Final Unreclaimed Sites: Ur-07 Site Evaluation Summary Report (Sesr), Molly Roby
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Cytotoxicity Of Bioactive Peptides From Cowpea (Vigna Unguiculata L. Walp) Against Breast Cancer Cells (Mcf-7), Dian R. Ningsih, Zusfahair Zusfahair, Ely Setiawan, Purwati Purwati, Kasta Gurning, Fitri A. Puspita Sari, Elya Widiawati
Cytotoxicity Of Bioactive Peptides From Cowpea (Vigna Unguiculata L. Walp) Against Breast Cancer Cells (Mcf-7), Dian R. Ningsih, Zusfahair Zusfahair, Ely Setiawan, Purwati Purwati, Kasta Gurning, Fitri A. Puspita Sari, Elya Widiawati
Karbala International Journal of Modern Science
Cancer is characterized by dysregulated metabolic signaling pathways, leading to uncontrolled cellular proliferation. Current cancer treatments, which involve surgery, radiotherapy, and chemotherapy, still cause adverse systemic toxicities. Accordingly, one possible effort that can be undertaken is to explore safe anticancer substances from protein sources such as peptides. Bioactive peptides can be isolated by hydrolyzing cowpea (Vigna unguiculata L. Walp) protein with trypsin. The objectives of this study were to isolate and fractionate bioactive peptides from cowpea, to determine the anticancer activity of peptide fractions, to identify active peptide fractions as anticancer agents using Liquid Chromatography High Resolution Mass Spectrometry …
Exogenous Ribosome Incorporation Induces Lineage Transdifferentiation In Intestinal And Liver Cancer Cells, Haoxuan Gu, Nadia Wahyuningsih, Keisuke Yamashita, Shota Inoue, Fuchao Tan, Mani Sharaki, Muhaimin Rifa’I, Kunimasa Ohta
Exogenous Ribosome Incorporation Induces Lineage Transdifferentiation In Intestinal And Liver Cancer Cells, Haoxuan Gu, Nadia Wahyuningsih, Keisuke Yamashita, Shota Inoue, Fuchao Tan, Mani Sharaki, Muhaimin Rifa’I, Kunimasa Ohta
Karbala International Journal of Modern Science
It has previously been shown that exogenous bacterial ribosomes added to somatic cells and various cancer cell lines generate ribosome-induced cell clusters (RICs) capable of transdifferentiating into multiple cellular lineages. However, the scope of ribosome-induced transdifferentiation in cancer cells remains poorly understood. This study aimed to analyze the effects of exogenous ribosome incorporation on human cancer cell lines, specifically the intestinal epithelial cell line Caco-2 and the hepatocellular carcinoma cell line HepG2. Caco-2 and HepG2 cells were cultured with purified bacterial ribosomes in human ES/iPS cell medium after trypsinization, resulting in the formation of ribosome-induced Caco-2 (RICs-Ca) and HepG2 (RICs-He) …