Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Physical Sciences and Mathematics

Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 1021 - 1050 of 4286

Full-Text Articles in Entire DC Network

Strategic Perspective Of Leveraging New Generation Information Technology To Enable Modernization Of Emergency Management, Haibo Zhang, Xinyu Dai, Depei Qian, Jian Lyu Dec 2022

Strategic Perspective Of Leveraging New Generation Information Technology To Enable Modernization Of Emergency Management, Haibo Zhang, Xinyu Dai, Depei Qian, Jian Lyu

Bulletin of Chinese Academy of Sciences (Chinese Version)

The application and development of the new generation information technology is a vital support to realize the modernization of emergency management. At present, the new generation information technology such as big data and artificial intelligence has been widely used in natural disasters, safe production, and other fields. It has improved the monitoring and early warning, regulation and law enforcement, command and decision support, rescue, and social mobilization capabilities of governments, promoted the level of intrinsic safety of enterprises, provided important support for the precise prevention and control of the COVID-19, and increased the efficiency of China’s emergency management and sense …


Mitigation Impact Of Statewide Non-Pharmaceutical Policies On Covid-19: An Application Of Infectious Disease Transmission Model And Partially Observed Markov Process To New Mexico, Xingya Ma Dec 2022

Mitigation Impact Of Statewide Non-Pharmaceutical Policies On Covid-19: An Application Of Infectious Disease Transmission Model And Partially Observed Markov Process To New Mexico, Xingya Ma

Mathematics & Statistics ETDs

This thesis is an application of epidemiological models for infectious disease transmission and the use of partially observed Markov process (POMP) for model fitting. It focuses on COVID-19 pandemic in the state of New Mexico. The analysis covered March 2020 to June 2021. Daily data of COVID19 cases and deaths and a daily index of eleven statewide government non-pharmaceutical intervention (NPI) policies were collected from six public sources and were validated. These data were integrated through the Susceptible-Exposed-Infected-Removed (SEIR) model. Estimated daily transmission rates between the model compartments quantify the impact of the mitigation policies, and show that transmission rates …


A Bayesian Susceptible-Infectious-Hospitalized-Ventilated-Recovered Model To Predict Demand For Covid-19 Inpatient Care In A Large Healthcare System, Stella Coker Watson Self Ph.D., Ms, Rongjie Huang, Shrujan Amin, Joseph Ewing, Carolina Rudisill, Alexander C. Mclain Ph.D. Dec 2022

A Bayesian Susceptible-Infectious-Hospitalized-Ventilated-Recovered Model To Predict Demand For Covid-19 Inpatient Care In A Large Healthcare System, Stella Coker Watson Self Ph.D., Ms, Rongjie Huang, Shrujan Amin, Joseph Ewing, Carolina Rudisill, Alexander C. Mclain Ph.D.

Faculty Publications

The COVID-19 pandemic has strained healthcare systems in many parts of the United States. During the early months of the pandemic, there was substantial uncertainty about whether the large number of COVID-19 patients requiring hospitalization would exceed healthcare system capacity. This uncertainty created an urgent need to accurately predict the number of COVID-19 patients that would require inpatient and ventilator care at the local level. As the pandemic progressed, many healthcare systems relied on such predictions to prepare for COVID-19 surges and to make decisions regarding staffing, the discontinuation of elective procedures, and the amount of personal protective equipment (PPE) …


A Bayesian Susceptible-Infectious-Hospitalized-Ventilated-Recovered Model To Predict Demand For Covid-19 Inpatient Care In A Large Healthcare System, Stella Coker Watson Self Ph.D., Ms, Rongjie Huang, Shrujan Amin, Joseph Ewing, Caroline Rudisill, Alexander C. Mclain Dec 2022

A Bayesian Susceptible-Infectious-Hospitalized-Ventilated-Recovered Model To Predict Demand For Covid-19 Inpatient Care In A Large Healthcare System, Stella Coker Watson Self Ph.D., Ms, Rongjie Huang, Shrujan Amin, Joseph Ewing, Caroline Rudisill, Alexander C. Mclain

Faculty Publications

The COVID-19 pandemic has strained healthcare systems in many parts of the United States. During the early months of the pandemic, there was substantial uncertainty about whether the large number of COVID-19 patients requiring hospitalization would exceed healthcare system capacity. This uncertainty created an urgent need to accurately predict the number of COVID-19 patients that would require inpatient and ventilator care at the local level. As the pandemic progressed, many healthcare systems relied on such predictions to prepare for COVID-19 surges and to make decisions regarding staffing, the discontinuation of elective procedures, and the amount of personal protective equipment (PPE) …


Systems Level Analysis Of Organelle Biogenesis In Saccharomyces Cerevisiae, Kiandokht Panjtan Amiri Dec 2022

Systems Level Analysis Of Organelle Biogenesis In Saccharomyces Cerevisiae, Kiandokht Panjtan Amiri

Arts & Sciences Graduate Student Theses and Dissertations

Eukaryotic cells contain hundreds of subcellular structures that serve different functions to maintain cellular homeostasis. A hallmark of Eukaryotic cells is its compartmentalization into membrane-bound organelles. One of the grand challenges in quantitative cell biology is understanding the precision with which cells assemble and maintain subcellular organelles. Despite identification of numerous molecular factors that regulate organelle sizes we lack insight into the quantitative principles underlying organelle size control. We examine organelle sizes from Saccharomyces cerevisiae and human iPS cells with mathematical theory to show that cells can robustly control average fluctuations in organelle size. By demonstrating that organelle sizes obey …


A Robust Random Forest Prediction Model For Mother-To-Child Hiv Transmission Based On Individual Medical History, Rebecca Chaula Dec 2022

A Robust Random Forest Prediction Model For Mother-To-Child Hiv Transmission Based On Individual Medical History, Rebecca Chaula

Tanzania Journal of Engineering and Technology (TJET)

Human Immunodeficiency Virus (HIV) continues to be a leading cause of mortality and reduces manpower throughout the world. HIV transmission from mother to child is still a global challenge in health research. According to UNAIDS, in every 7 girls, 6 are found to be newly infected among adolescents whereby 15-24 years are likely to be living with HIV which is the maternal age and likely to transfer to the child. Machine learning methods have been used to predict HIV/AIDS transmission from mother to child but left behind some important considerations including the use of patient-level information and techniques in balancing …


Poliovirus Detection In Las Vegas Wastewater, Sage Boss, Hayley Baker, Ching-Lan Chang Dec 2022

Poliovirus Detection In Las Vegas Wastewater, Sage Boss, Hayley Baker, Ching-Lan Chang

Undergraduate Research Symposium Posters

Wastewater surveillance for poliovirus is a useful tool for spatial surveillance and evaluation of immunization efficacy. Polio testing in wastewater has been conducted since the 1980s in Finland and Israel, and the virus was recently discovered in New York. With increasing concern regarding the vaccination of children against the virus, there has been worry that polio cases could once again present themselves in the Las Vegas Valley. By testing for the virus in wastewater, we can monitor any new cases or outbreaks that occur and inform authorities as to the location and viral count. The wastewater samples were collected at …


The Global Effects Of Climate Change: Detrimental Impacts On The Environment, Ecosystem, Coral Reefs, Human Health/Well-Being, And Global Economy, Lucky Heng Dec 2022

The Global Effects Of Climate Change: Detrimental Impacts On The Environment, Ecosystem, Coral Reefs, Human Health/Well-Being, And Global Economy, Lucky Heng

Undergraduate Research Symposium Posters

Despite criticism, scientists have been continuing to find more evidence to prove that the threats on the coral reefs around the world are real. The impact of rising climate temperature, pollution, ocean acidification, etc. has been leading to increasing amounts of mass bleaching and a massive decline in coral reefs in past decades. This research study utilizes a systematic literature review and secondary research to collect, analyze and provide evidence that climate change impacts the ecosystem, and marine life (coral reefs) species on the planet. By addressing the impact of climate change and its significance on the ecosystem and global …


Evidence-Based Study: The Effect Of The Covid-19 Pandemic On Post-Secondary Enrollment And Chosen Fields Of Study, Hannah Fields '25 Dec 2022

Evidence-Based Study: The Effect Of The Covid-19 Pandemic On Post-Secondary Enrollment And Chosen Fields Of Study, Hannah Fields '25

Student Research

The onset of the COVID-19 pandemic in the United States in March of 2020 derailed educational systems at all levels. Specifically, at the post-secondary level, the pandemic sent many students online or forced them to take a fifth year to complete their degrees. As a result, post-secondary enrollment rates are likely to have dropped to reflect these changing post-COVID views surrounding education. Additionally, changing viewpoints about the essentiality of certain jobs and roles changed the chosen fields of study of these same students. Data for this study was collected by way of a short-scale meta-analysis, and enrollment rates were split …


Six-Dimensional Single-Molecule Imaging With Isotropic Resolution Using A Multi-View Reflector Microscope, Oumeng Zhang, Zijian Guo, Yuanyuan He, Tingting Wu, Michael D. Vahey, Matthew D. Lew Dec 2022

Six-Dimensional Single-Molecule Imaging With Isotropic Resolution Using A Multi-View Reflector Microscope, Oumeng Zhang, Zijian Guo, Yuanyuan He, Tingting Wu, Michael D. Vahey, Matthew D. Lew

Electrical & Systems Engineering Publications and Presentations

Imaging of both the positions and orientations of single fluorophores, termed single-molecule orientation-localization microscopy, is a powerful tool for the study of biochemical processes. However, the limited photon budget associated with single-molecule fluorescence makes high-dimensional imaging with isotropic, nanoscale spatial resolution a formidable challenge. Here we realize a radially and azimuthally polarized multi-view reflector (raMVR) microscope for the imaging of the three-dimensional (3D) positions and 3D orientations of single molecules, with precisions of 10.9 nm and 2.0° over a 1.5-μm depth range. The raMVR microscope achieves 6D super-resolution imaging of Nile red molecules transiently bound to lipid-coated spheres, accurately resolving …


Exposure Of Egyptian Rousette Bats (Rousettus Aegyptiacus) And A Little Free-Tailed Bat (Chaerephon Pumilus) To Alphaviruses In Uganda, Rebekah C. Kading, Erin M. Borland, Eric C. Mossel, Teddy Nakayiki, Betty Nalikka, Jeremy P. Ledermann, Mary B. Crabtree, Nicholas A. Panella, Luke Nyakarahuka, Amy T. Gilbert, Julian C. Kerbis-Peterhans, Jonathan S. Towner, Brian R. Amman, Tara K. Sealy, Barry R. Miller, Julius J. Lutwama, Robert M. Kityo, Ann M. Powers Dec 2022

Exposure Of Egyptian Rousette Bats (Rousettus Aegyptiacus) And A Little Free-Tailed Bat (Chaerephon Pumilus) To Alphaviruses In Uganda, Rebekah C. Kading, Erin M. Borland, Eric C. Mossel, Teddy Nakayiki, Betty Nalikka, Jeremy P. Ledermann, Mary B. Crabtree, Nicholas A. Panella, Luke Nyakarahuka, Amy T. Gilbert, Julian C. Kerbis-Peterhans, Jonathan S. Towner, Brian R. Amman, Tara K. Sealy, Barry R. Miller, Julius J. Lutwama, Robert M. Kityo, Ann M. Powers

United States Department of Agriculture Wildlife Services: Staff Publications

The reservoir for zoonotic o’nyong-nyong virus (ONNV) has remained unknown since this virus was first recognized in Uganda in 1959. Building on existing evidence for mosquito bloodfeeding on various frugivorous bat species in Uganda, and seroprevalence for arboviruses among bats in Uganda, we sought to assess if serum samples collected from bats in Uganda demonstrated evidence of exposure to ONNV or the closely related zoonotic chikungunya virus (CHIKV). In total, 652 serum samples collected from six bat species were tested by plaque reduction neutralization test (PRNT) for neutralizing antibodies against ONNV and CHIKV. Forty out of 303 (13.2%) Egyptian rousettes …


(R2022) Mathematical Modelling Of Tuberculosis And Covid-19 Co-Infection In India: A Real Data Analysis On Concomitant Diseases, Vijai Shanker Verma, Harshita Kaushik, Archana Singh Bhadauria Dec 2022

(R2022) Mathematical Modelling Of Tuberculosis And Covid-19 Co-Infection In India: A Real Data Analysis On Concomitant Diseases, Vijai Shanker Verma, Harshita Kaushik, Archana Singh Bhadauria

Applications and Applied Mathematics: An International Journal (AAM)

In this paper, we have proposed an epidemiological model to study the dynamics of two concomitant diseases Tuberculosis (TB) and COVID-19. Here, we have formulated a deterministic compartmental model as an extended form of the classical SIS model. First, the basic reproduction number R0 is derived and then stability analysis of the model is done. It is observed that the disease-free equilibrium is stable when R0 is less than one and the endemic equilibrium is stable only when R0 is greater than one. Numerical simulation is carried out to illustrate the theoretical findings and to study the …


(R1522) Modelling The Influence Of Desertic Aerosols On The Transmission Dynamics Of Neisseria Meningitidis Serogroup A, Francis Signing, Berge Tsanou, Samuel Bowong Dec 2022

(R1522) Modelling The Influence Of Desertic Aerosols On The Transmission Dynamics Of Neisseria Meningitidis Serogroup A, Francis Signing, Berge Tsanou, Samuel Bowong

Applications and Applied Mathematics: An International Journal (AAM)

This paper assesses the role of desert aerosols and vaccine on the transmission dynamics of Neisseria Meningitis serogroup A (NmA). It is biologically well-documented that the inhalation of aerosol dust and its presence in the nasal cavity weakens the nasopharyngeal mucosa by damaging the mucosal barrier and inhibiting the mucosal immune defenses of susceptible and vaccinated individuals. We address the latter by proposing and analyzing a mathematical model for the dynamics of NmA that specifically accounts for the fast progression of susceptible and vaccinated individuals to the invasive stage of the disease. We compute the basic reproduction number and use …


Data Discovery Analysis On Complex Time Series Data, Peter Lawrence Severynen Dec 2022

Data Discovery Analysis On Complex Time Series Data, Peter Lawrence Severynen

Computer Science and Engineering Theses - Archive

Complex time series are a ubiquitous form of data in the modern world. They have wide application across many different fields of scientific inquiry and business endeavor. Time series are used to understand and forecast weather patterns, voting patterns, computer network traffic, population health outcomes, demographic changes, the results of scientific experiments, and the performance of stocks and mutual funds. But time series can be difficult to analyze by conventional methods when the data is multivariate, incomplete, or in different formats. To address these issues, an investigation of several multivariate time series datasets was performed using the methods of automatic …


Metabolic Alterations And Cardiovascular Risk After Hepatitis C Cure In Subjects With Or At Risk For Hiv, Christophe Maxime Fokoua Dongmo Dec 2022

Metabolic Alterations And Cardiovascular Risk After Hepatitis C Cure In Subjects With Or At Risk For Hiv, Christophe Maxime Fokoua Dongmo

Legacy Theses & Dissertations (2009 - 2024)

Background. Hepatitis C virus (HCV) infection engenders substantial metabolic changes. These changes are altered when the virus is cleared after successful treatment. We measured these metabolic alterations that occur after HCV cure; further, we assessed whether these alterations differed in subgroups defined by patients’ characteristics.


Machine Learning For Early Detection Of Pediatric Sepsis, Glory Manson-Endeboh Dec 2022

Machine Learning For Early Detection Of Pediatric Sepsis, Glory Manson-Endeboh

Graduate Theses and Dissertations

Sepsis is a host response to infection in both adults and children. It contributes to approximately 1.7 million cases annually with nearly 270,000 annual deaths in the United States. In the United States, the financial burden of sepsis on survivors and their families including the hospitals is over $4.8 billion, at approximately $64,280 per hospitalization. The first goal of this thesis research is to develop efficient machine learning models to predict pediatric sepsis accurately for inpatients. The second objective is to develop machine learning methods to determine how early sepsis can be detected to mitigate mortality. We examine data collected …


Use Of Healthcare Utilization Records For Analyzing Trends In Clinical Toxoplasmosis: A Comparison Of Nevada And The United States, Elijah Kreutzer Dec 2022

Use Of Healthcare Utilization Records For Analyzing Trends In Clinical Toxoplasmosis: A Comparison Of Nevada And The United States, Elijah Kreutzer

UNLV Theses, Dissertations, Professional Papers, and Capstones

Toxoplasmosis, a zoonotic disease caused by the parasitic protist Toxoplasma gondii, is a ubiquitous, global public health concern with a wide variety of clinical manifestations. Surveillance for the disease is lacking even in developed countries, and what surveillance is present most often focuses on pregnant women. This research investigated trends in clinical toxoplasmosis in Nevada and nationally to address the lack of knowledge concerning how Nevada discharges compare to national discharges in cases of toxoplasmosis. Specifically, this research sought to determine what characterizes toxoplasmosis in Nevada across inpatient, outpatient, and emergency department settings, as well as how these cases differ …


Divergent Serpentoviruses In Free-Ranging Invasive Pythons And Native Colubrids In Southern Florida, United States, Steven B. Tillis, Jillian M. Josimovich, Melissa A. Miller, Laura L. Hoon-Hanks, Arik M. Hartmann, Natalie M. Claunch, Marley E. Iredale, Tracey D. Logan, Amy A. Yackel Adams, Ian A. Bartoszek, John S. Humphrey, Bryan M. Kluever, Mark D. Stenglein, Robert N. Reed, Christina M. Romagosa, James F.X. Wellehan, Robert J. Ossiboff Dec 2022

Divergent Serpentoviruses In Free-Ranging Invasive Pythons And Native Colubrids In Southern Florida, United States, Steven B. Tillis, Jillian M. Josimovich, Melissa A. Miller, Laura L. Hoon-Hanks, Arik M. Hartmann, Natalie M. Claunch, Marley E. Iredale, Tracey D. Logan, Amy A. Yackel Adams, Ian A. Bartoszek, John S. Humphrey, Bryan M. Kluever, Mark D. Stenglein, Robert N. Reed, Christina M. Romagosa, James F.X. Wellehan, Robert J. Ossiboff

United States Department of Agriculture Wildlife Services: Staff Publications

Burmese python (Python bivittatus) is an invasive snake that has significantly affected ecosystems in southern Florida, United States. Aside from direct predation and competition, invasive species can also introduce nonnative pathogens that can adversely affect native species. The subfamily Serpentovirinae (order Nidovirales) is composed of positive-sense RNA viruses primarily found in reptiles. Some serpentoviruses, such as shingleback nidovirus, are associated with mortalities in wild populations, while others, including ball python nidovirus and green tree python nidovirus can be a major cause of disease and mortality in captive animals. To determine if serpentoviruses were present in invasive Burmese …


Modulation Of Non-Diffracting Hermite Gaussian Beams And Nonlinear Optical Microscopy For Nanoscale Sulfur Imaging, Gilberto Navarro Dec 2022

Modulation Of Non-Diffracting Hermite Gaussian Beams And Nonlinear Optical Microscopy For Nanoscale Sulfur Imaging, Gilberto Navarro

Open Access Theses & Dissertations

Hermite Gaussian beams are the solutions of the scalar paraxial wave equation in Cartesian coordinates. A method was developed to modulate the intensity profile of non-diffracting Hermite Gaussian (HG) beams. The original HG beamâ??s intensity profile consists of high intense corner lobes and low intense central lobes which is not ideal for structured illumination in light-field microscopy. The modulated HG beams were generated by multiplying the original HGâ??s beam envelope by a super-Gaussian envelope to modify the intensity profile to attain equal intensity lobes. The propagation of the original HG beam and modulated HG beam were compared to determine that …


A Two-Layer Network Propagation Model Of Awareness Diffusion And Seir Epidemic, Yurong Song, Yulin Bao, Ruqi Li Nov 2022

A Two-Layer Network Propagation Model Of Awareness Diffusion And Seir Epidemic, Yurong Song, Yulin Bao, Ruqi Li

Journal of System Simulation

Abstract: In order to understand the transmission characteristics of epidemics similar to COVID-19 (coronavirus disease 2019) with obvious expose period, a two-layer network transmission model considering time-varying factors is proposed to make corresponding predictions and measures. The UAU (unaware-aware-unaware) information transmission model is used to represent the diffusion process of conscious information about epidemic. In the underlying network, the susceptible-exposed-infected- recovered (SEIR) epidemic-like transmission model with latent state is used to describe the epidemic transmission process affected by conscious information. The MMCA (microscopic Markov chain approach) is used to deduce the transmission threshold of epidemics diseases. By analyzing the key …


Association Between The Health Belief Model, Exercise, And Nutrition Behaviors During The Covid-19 Pandemic, Keagan Kiely, Bill Mase, Andrew R. Hansen, Jessica S. Schwind Nov 2022

Association Between The Health Belief Model, Exercise, And Nutrition Behaviors During The Covid-19 Pandemic, Keagan Kiely, Bill Mase, Andrew R. Hansen, Jessica S. Schwind

Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

Introduction: The COVID-19 pandemic has affected our nation’s health further than the infection it causes. Physical activity levels and dietary intake have suffered while individuals grapple with the changes in behavior to reduce viral transmission. With unique nuances regarding the access to physical activity and nutrition during the pandemic, the constructs of Health Belief Model (HBM) may present themselves differently in nutrition and exercise behaviors compared to precautions implemented to reduce viral transmission studied in previous research. The purpose of this study was to investigate the extent of exercise and nutritional behavior change during the COVID-19 pandemic and explain the …


Pandemic Fatigue Impedes Mitigation Of Covid-19 In Hong Kong, Zhanwei Du, Lin Wang, Songwei Shan, Dickson Lam, Tim K. Tsang, Jingyi Xiao, Huizhi Gao, Bingyi Yang, Sheikh Taslim Ali, Sen Pei, Isaac Chun-Hai Fung, Eric H. Y. Lau, Qiuyan Liao, Peng Wu, Lauren Ancel Meyers, Gabriel M. Leung, Benjamin Cowling Nov 2022

Pandemic Fatigue Impedes Mitigation Of Covid-19 In Hong Kong, Zhanwei Du, Lin Wang, Songwei Shan, Dickson Lam, Tim K. Tsang, Jingyi Xiao, Huizhi Gao, Bingyi Yang, Sheikh Taslim Ali, Sen Pei, Isaac Chun-Hai Fung, Eric H. Y. Lau, Qiuyan Liao, Peng Wu, Lauren Ancel Meyers, Gabriel M. Leung, Benjamin Cowling

Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

Hong Kong has implemented stringent public health and social measures (PHSMs) to curb each of the four COVID-19 epidemic waves since January 2020. The third wave between July and September 2020 was brought under control within 2 m, while the fourth wave starting from the end of October 2020 has taken longer to bring under control and lasted at least 5 mo. Here, we report the pandemic fatigue as one of the potential reasons for the reduced impact of PHSMs on transmission in the fourth wave. We contacted either 500 or 1,000 local residents through weekly random-digit dialing of landlines …


Laboratory Evaluation And Field Feasibility Of Micro-Encapsulated Insecticide Effect On Rhodnius Prolixus And Triatoma Dimidiata Mortality In Rural Households In Boyaca, Colombia, Lidia Gual-Gonzalez, Manuel Medina, Cesar Valverde-Castro, Virgilio Beltran, Rodrigo Caro, Omar Triana-Chavez, Melissa Nolan Ph.D., Mph, Omar Cantillo-Barraza Nov 2022

Laboratory Evaluation And Field Feasibility Of Micro-Encapsulated Insecticide Effect On Rhodnius Prolixus And Triatoma Dimidiata Mortality In Rural Households In Boyaca, Colombia, Lidia Gual-Gonzalez, Manuel Medina, Cesar Valverde-Castro, Virgilio Beltran, Rodrigo Caro, Omar Triana-Chavez, Melissa Nolan Ph.D., Mph, Omar Cantillo-Barraza

Faculty Publications

Chagas disease is a neglected vector-borne zoonosis caused by the parasite Trypanosoma cruzi that is primarily transmitted by insects of the subfamily Triatominae. Although control efforts targeting domestic infestations of Rhodnius prolixus have been largely successful, with several regions in Boyacá department certified free of T. cruzi transmission by intradomicile R. prolixus, novel native species are emerging, increasing the risk of disease. Triatoma dimidiata is the second most important species in Colombia, and conventional control methods seem to be less effective. In this study we evaluated the efficacy and usefulness of micro-encapsulated insecticide paints in laboratory conditions and its …


Physics-Informed Neural Networks For Informed Vaccine Distribution In Heterogeneously Mixed Populations, Alvan Arulandu, Padmanabhan Seshaiyer Nov 2022

Physics-Informed Neural Networks For Informed Vaccine Distribution In Heterogeneously Mixed Populations, Alvan Arulandu, Padmanabhan Seshaiyer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


On Analysis Of Effectiveness Controlling Covid-19 With Quarantine And Vaccination Compartments In Indonesia, Prihantini Prihantini Nov 2022

On Analysis Of Effectiveness Controlling Covid-19 With Quarantine And Vaccination Compartments In Indonesia, Prihantini Prihantini

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modeling The Impact Of Hospitalization On The Death Rate Of An Ebola Outbreak, Erin N. Bodine, Jana V. Turner Nov 2022

Modeling The Impact Of Hospitalization On The Death Rate Of An Ebola Outbreak, Erin N. Bodine, Jana V. Turner

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Dynamics Of A Diffusive Vaccination Model With Therapeutic Impact And Non-Linear Incidence Rates, Md Shahriar Mahmud Nov 2022

Dynamics Of A Diffusive Vaccination Model With Therapeutic Impact And Non-Linear Incidence Rates, Md Shahriar Mahmud

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Covid-19 And Challenges To The Classical Theory Of Epidemics, Simon Levin Nov 2022

Covid-19 And Challenges To The Classical Theory Of Epidemics, Simon Levin

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Understanding The Behavior, Challenges, And Privacy Risks In Digital Technology Use By Nursing Professionals, Ankit Shrestha, Danielle M. Graham, Prakriti Dumaru, Rizu Paudel, Kristin A. Searle, Mahdi Nasrullah Al-Ameen Nov 2022

Understanding The Behavior, Challenges, And Privacy Risks In Digital Technology Use By Nursing Professionals, Ankit Shrestha, Danielle M. Graham, Prakriti Dumaru, Rizu Paudel, Kristin A. Searle, Mahdi Nasrullah Al-Ameen

Computer Science Student Research

With the growing adoption of digital technology in healthcare organizations, it is important to understand nursing professionals’ behavior and challenges, and the corresponding privacy implications around digital technology use. To this end, we conducted semi-structured interviews with 21 participants (16 nursing professionals, and five nursing faculties) in the USA. In our study with nursing professionals, we explored how they used digital technology and protected sensitive health data at their workplace. We investigated their understanding of privacy breaches and possible consequences, the challenges they encountered to maintaining privacy, and their workarounds to deal with such issues. We looked into the support …


Sars-Cov-2 Spike Conformation Determines Plasma Neutralizing Activity Elicited By A Wide Panel Of Human Vaccines, John E. Bowen, Young-Jun Park, Cameron Stewart, Jack T. Brown, William K. Sharkey, Alexandra C. Walls, Anshu Joshi, Kumail Ahmed, Asefa Shariq, Najeeha Talat Iqbal Nov 2022

Sars-Cov-2 Spike Conformation Determines Plasma Neutralizing Activity Elicited By A Wide Panel Of Human Vaccines, John E. Bowen, Young-Jun Park, Cameron Stewart, Jack T. Brown, William K. Sharkey, Alexandra C. Walls, Anshu Joshi, Kumail Ahmed, Asefa Shariq, Najeeha Talat Iqbal

Department of Paediatrics and Child Health

Numerous safe and effective coronavirus disease 2019 vaccines have been developed worldwide that use various delivery technologies and engineering strategies. We show here that vaccines containing prefusion-stabilizing S mutations elicit antibody responses in humans with enhanced recognition of S and the S1 subunit relative to postfusion S as compared with vaccines lacking these mutations or natural infection. Prefusion S and S1 antibody binding titers positively and equivalently correlated with neutralizing activity, and depletion of S1-directed antibodies completely abrogated plasma neutralizing activity. We show that neutralizing activity is almost entirely directed to the S1 subunit and that variant cross-neutralization is mediated …