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Articles 3331 - 3360 of 64945
Full-Text Articles in Entire DC Network
Re: June 2025 Berkeley Pit Migratory Waterfowl Protection Monthly Report, Mark Thompson, Loren Burmeister
Re: June 2025 Berkeley Pit Migratory Waterfowl Protection Monthly Report, Mark Thompson, Loren Burmeister
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Re: Butte Priority Soils Operable Unit (Bpsou) Superfund Operation And Maintenance (O&M) Request For Maintenance – Kelley Stormwater Channels (Dated April 22, 2025), Josh Bryson
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Re: Comments On The Repository, Haul Route, And Pipeline Geotechnical Pre-Design Investigation Summary Report (Dated May 13, 2025), Emma Rott
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Re: Comment Letter For Butte Priority Soils Operable Unit (Bpsou) Draft 2024 Groundwater Monitoring Data Summary Report (Dated May 30, 2025), Emma Rott
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Zambia's Poor Septic Waste Management: A Disaster In Waiting, Andrew Mwape
Zambia's Poor Septic Waste Management: A Disaster In Waiting, Andrew Mwape
School of Natural Resources: Faculty Publications
In the shadows of Zambia’s rapidly growing urban and peri-urban communities lies an invisible but mounting threat, the mismanagement of septic waste. While national dialogue often focuses on economic development, climate change, or energy, the sanitation crisis receives little public attention, yet it poses an equally severe risk to public health, environmental integrity, and sustainable urbanization. Zambia’s poor septic waste management, if left unaddressed, is a disaster in waiting.
Septic waste refers to the wastewater and solid waste that flows from toilets, sinks, and other domestic plumbing fixtures into on-site sanitation systems such as septic tanks or pit latrines. This …
Design And Investigation Of Triarylamine Functionalized Luminophores For Multi-Functional And Stimuli-Responsive Applications, Sasikala R
Theses and Dissertations
Organic solid-state fluorescent materials have garnered attention over many decades in virtue of their contribution in the development of LED devices and biomedical applications. Nevertheless, the potential of fluorescent molecules in device applications was underused due to aggregation-caused quenching (ACQ) effect. The ACQ effect commonly quenches the organic molecules fluorescence intensity in the aggregated or condensed state, which can significantly influence their performance in practical applications.
The organic polyaromatic fluorophores exhibit strong fluorescence in the solution state. After culmination of years of work, Prof. Tang’s research group discovered a new phenomenon of aggregation-induced emission (AIE) in the fluorescence molecules constructed …
Multivariable Optimal Control For Hemodialysis: A Physiologically-Grounded Simulation Study, Redemtus Heru Tjahjana, Ratna Herdiana, Zani Anjani H.S.M. Rafsanjani, Yogi Ahmad Erlangga
Multivariable Optimal Control For Hemodialysis: A Physiologically-Grounded Simulation Study, Redemtus Heru Tjahjana, Ratna Herdiana, Zani Anjani H.S.M. Rafsanjani, Yogi Ahmad Erlangga
All Works
This study introduces a novel multivariable optimal control framework for hemodialysis, which uniquely integrates five physiological states (blood urea concentration, fluid volume, blood pressure, electrolytes, and hemoglobin) with three clinically adjustable inputs (ultrafiltration rate, blood flow, and dialysate composition). By employing the limited-memory Broyden-Fletcher-Goldfarb-Shanno-B (L-BFGS-B) algorithm with patient-specific box constraints, the model enforces patient-specific physiological safety limits while dynamically balancing clinical targets. Numerical simulations demonstrate the stabilization of key parameters within ±5% of clinical benchmarks (e.g., KDIGO guidelines), though deviations in the hemodynamic responses underscore the need for adaptive control in real-world scenarios. Urea clearance trajectories align with efficacy patterns …
Digital Identity Management As A Critical Criminal Justice And Homeland Security Legal Issue: A Qualitative Analysis Of The Reasonable Person Factors Involved In Court Decisions, William H. Nicholson
Digital Identity Management As A Critical Criminal Justice And Homeland Security Legal Issue: A Qualitative Analysis Of The Reasonable Person Factors Involved In Court Decisions, William H. Nicholson
Doctoral Dissertations and Projects
The purpose of this descriptive qualitative applied study is to define and explain through analysis the reasonable person standard as it relates to prosecution and sentencing computer crime cases involving digital identities while addressing the problem of digital anonymity. This has been done by analyzing computer crime cases with the advent of current and planned technologies, and surveying potential jurors to understand the current state of knowledge of digital attribution. This descriptive qualitative research method analyzed the problem through the use of criminological theories of control and social learning theory to better understand the reasonable person standard in computer crime …
Towards Sustainable Community-Designed Ai Systems In The Public Sector, Victoria Chui, Kelly Mcconvey, Erina Seh-Young Moon, Maya Ghai, Shion Guha
Towards Sustainable Community-Designed Ai Systems In The Public Sector, Victoria Chui, Kelly Mcconvey, Erina Seh-Young Moon, Maya Ghai, Shion Guha
Health Services and Informatics Research
Advancements in data-driven modeling and artificial intelligence applications in public sector settings can lead to increased ten sions between stakeholder needs and tangible model capabilities from developers. Engaging multiple stakeholder groups in model development through the gleaning of sociotechnical, theoretical in sights using qualitative methods can contribute to more impactful, beneficial model solutions. Qualitative methods can complement quantitative model development, emphasizing stakeholder priori ties, informing model design choices, and promoting sustainable connections and model longevity. We are excited to discuss human centered qualitative methods, sustainable modeling practices, and community engagement in this workshop, engaging with scholars on system-level modeling strategies.
A Comprehensive Deep Learning System With Mgrf Modeling For Predicting Breast Cancer Response To Neoadjuvant Chemotherapy, Ahmed Sharafeldeen, Fatma Taher, Norah Saleh Alghamdi, Eman Alnaghy, Reham Alghandour, Khadiga M. Ali, Sameh Shamaa, Abdelrahman Gamal, Mohammed Ghazal, Sohail Contractor, Ayman El-Baz
A Comprehensive Deep Learning System With Mgrf Modeling For Predicting Breast Cancer Response To Neoadjuvant Chemotherapy, Ahmed Sharafeldeen, Fatma Taher, Norah Saleh Alghamdi, Eman Alnaghy, Reham Alghandour, Khadiga M. Ali, Sameh Shamaa, Abdelrahman Gamal, Mohammed Ghazal, Sohail Contractor, Ayman El-Baz
All Works
Accurate prediction of breast cancer (BC) response to neoadjuvant chemotherapy (NAC) is critical for tailoring treatment strategies and improving patient outcomes. This study introduces a novel deep learning-based framework that integrates multi-parametric magnetic resonance imaging (MRI) (i.e., T1, T2, STIR, and DWI), along with clinical and molecular subtype markers, to classify tumor response into pathological complete response (pCR), partial response (PR), and stable disease (SD). First, tumor regions are delineated across MRI modalities and then modeled using a translation-invariant Markov-Gibbs random field (MGRF) with analytical parameter estimation to capture modality-specific spatial appearance patterns correlated with NAC response. Subsequently, diffusion-weighted MRI …
Collaborative Class Zine: Weekly Reflection Assignment With Powerpoint Template, Brett Whysel
Collaborative Class Zine: Weekly Reflection Assignment With Powerpoint Template, Brett Whysel
Open Educational Resources
Abstract
This collaborative class zine assignment uses a shared PowerPoint format to deepen student learning while building community. Students contribute visual reflections (graphics, diagrams, quotes, or doodles) weekly or periodically throughout the semester. Faculty provide reflection prompts about key takeaways and unclear concepts (sample prompts included). The resource includes both sample LMS instructions and a ready-to-use PowerPoint zine template that works across all disciplines. By combining metacognitive reflection with creative expression, students consolidate learning by finding new connections and applications. The collaborative format creates community connections and joy while students learn from peers' diverse perspectives.
A Longitudinal Analysis Of Morphological Shape Variation Of Spleen In Patients With Fontan Surgery, Varatharajan Nainamalai, Håvard Bjørke Jenssen, Mostafa Rezaeitaleshmahalleh, Djinaud Prophete, Jordan Gosnell, Sarah Khan, Marcus Haw, Jingfeng Jiang, Joseph Vettukattil
A Longitudinal Analysis Of Morphological Shape Variation Of Spleen In Patients With Fontan Surgery, Varatharajan Nainamalai, Håvard Bjørke Jenssen, Mostafa Rezaeitaleshmahalleh, Djinaud Prophete, Jordan Gosnell, Sarah Khan, Marcus Haw, Jingfeng Jiang, Joseph Vettukattil
Michigan Tech Publications
Background: Splenic size serves as a surrogate biomarker for predicting portal vein hyper-tension and liver abnormalities in subjects with Fontan Associated Liver Disease (FALD). We analyze the long-term shape variation of the spleen in FALD subjects using morphological shape features of radiomic features. Methods: We used 154 (84 from computed tomography and 70 from magnetic resonance) image volumes obtained from 36 individuals who underwent stage 3 Fontan procedure and 145 computed tomography images from controls to assess splenomegaly. To understand the splenomegaly, thirteen shape features of the spleen over three 10-year intervals, and variations between controls and FALD subjects were …
A Cancer Education Needs Assessment: Informing Middle-Aged Female Patients About The Relationships Between Obesity And Women’S Health Concerns In The Reproductive System, Breast, And Endometrial Health, Batul Mirza
MUSC Theses and Dissertations
Obesity significantly impacts women’s health, particularly among middle-aged women, by increasing the risk of hormone-sensitive cancers such as breast, endometrial, and reproductive system cancers. This study examines the educational needs of this demographic group regarding obesity-related cancer risks and explores effective intervention strategies. Obesity-induced mechanisms – hormonal imbalances, chronic inflammation, and insulin resistance – drive cancer susceptibility, emphasizing the need for targeted health education. The study employs a qualitative design, which includes interviews with subject matter experts (SMEs) and surveys of middle-aged women. The goal is to assess awareness, perceived barriers, and preferred learning methods. Findings suggest that with many …
Life Cycle Assessment Of New Jersey Offshore Wind, Meghann Smith, Nawal Shoaib, Pankaj Lal
Life Cycle Assessment Of New Jersey Offshore Wind, Meghann Smith, Nawal Shoaib, Pankaj Lal
Department of Earth and Environmental Studies Faculty Scholarship and Creative Works
As offshore wind gains momentum within US (United States) renewable energy goals, New Jersey's ambitious targets for offshore wind development represent a significant opportunity to reduce emissions and transition towards cleaner energy sources. This study presents a life cycle assessment (LCA) of a planned offshore wind farm off of New Jersey's coast, emphasizing the implications of a domestic supply chain. Key findings suggest that the offshore wind farm is projected to produce 0.013 kg CO2 kWh−1 of electricity generated, reflecting a 98 % decrease in carbon emissions compared to natural-gas-derived electricity. Further, when compared to carbon emissions from other renewable …
A Web Application For Generating Argument Maps For Essays Using Llms, Alexis R. Chalmers
A Web Application For Generating Argument Maps For Essays Using Llms, Alexis R. Chalmers
Theses
Argumentative writing is a critical skill that strengthens students’ reasoning, communication, and analytical abilities. However, maintaining a clear and organized argument structure while writing can be challenging. Argument maps — visual diagrams which explicitly show an argument’s structure — have been shown to improve students’ writing, but are rarely used outside of the planning stage of an essay due to the time and effort required to create them. Automatically generating argument maps from student essays helps students to evaluate the structure of their argument as they write and makes identifying unsupported claims visible. To evaluate whether large language models (LLMs) …
What Drives Weight Status Among Female University Students? A Machine Learning Analysis Of Sociodemographic, Dietary, And Lifestyle Determinants, Radwan Qasrawi, Abir Ajab, Leila Cheikh Ismail, Ayesha Al Dhaheri, Sharifa Alblooshi, Razan Abu Ghoush, Stephanny Vicuna Polo, Malak Amro, Suliman Thwib, Ghada Issa, Haleama Al Sabbah
What Drives Weight Status Among Female University Students? A Machine Learning Analysis Of Sociodemographic, Dietary, And Lifestyle Determinants, Radwan Qasrawi, Abir Ajab, Leila Cheikh Ismail, Ayesha Al Dhaheri, Sharifa Alblooshi, Razan Abu Ghoush, Stephanny Vicuna Polo, Malak Amro, Suliman Thwib, Ghada Issa, Haleama Al Sabbah
All Works
Background: Obesity and underweight are increasingly common among young adult women, often resulting from complex interactions between diet, lifestyle, and socioeconomic factors. This study addresses that gap by applying machine learning to a wide range of behavioral, dietary, and demographic data. The main research question asks: What are the key factors influencing weight status among female university students, and how accurately can machine learning models identify them? We hypothesize that different factors are significantly associated with underweight, overweight, and obesity, and that machine learning can reliably detect these patterns. The aim is to identify the strongest predictors and support more …
Secondary Malignancies In Patients With Meningioma: A Surveillance, Epidemiology, And End Results Data Analysis, Maxwell W. Pickles, Thomas Z. Rohan, Shreya Vinjamuri, Nikolaos Mouchtouris, Roger Murayi, David P. Bray, James J. Evans
Secondary Malignancies In Patients With Meningioma: A Surveillance, Epidemiology, And End Results Data Analysis, Maxwell W. Pickles, Thomas Z. Rohan, Shreya Vinjamuri, Nikolaos Mouchtouris, Roger Murayi, David P. Bray, James J. Evans
Department of Neurosurgery Faculty Papers
BACKGROUND: The risk of secondary primary malignancies (SPMs) in meningioma patients is not well understood. In this unidirectional analysis, we evaluated the risk of SPMs occurring following a primary diagnosis of meningioma.
METHODS: The Surveillance, Epidemiology, and End Results (SEER-17) database (2000-2020) was used to identify 124,769 meningioma patients from a total of 9,208,295 cancer cases. Standardized incidence ratios (SIRs) were calculated using SEER's statistical analysis package to evaluate SPM risk. Basic demographic and treatment information was collected as well.
RESULTS: Of the 124,769 patients, 11,411 (9.2%) received diagnoses of an SPM, which correlates to a higher risk than the …
Stranger Disputes: When Artificial Intelligence Turns Arbitration Upside Down, Imre Stephen Szalai
Stranger Disputes: When Artificial Intelligence Turns Arbitration Upside Down, Imre Stephen Szalai
Pepperdine Dispute Resolution Law Journal
Arbitration agreements are everywhere in the United States. These agreements already block access to courts in a troubling manner, and pursuant to these agreements, parties must resolve their disputes before a private, human arbitrator with broad, virtually unreviewable powers. However, with the growth of AI, companies could easily redraft their contracts to require arbitration before non-human bots or AI arbitrators instead of a human arbitrator. Based on the history, values, policy, and text of the Federal Arbitration Act (FAA), this Article concludes that the FAA would govern and support the use of an AI arbitrator. As a result, a pre-dispute …
The Response Of Mitochondrial Position To Glucose Stimulation In The Min6 Model System, Luis Perez
The Response Of Mitochondrial Position To Glucose Stimulation In The Min6 Model System, Luis Perez
Arts & Sciences Graduate Student Theses and Dissertations
The compartmentalization of eukaryotic cells into membrane-bound organelles with specific subcellular positioning enables precise spatial and temporal control of cellular functions. While functionally significant mitochondrial localization has been demonstrated in cells such as neurons, it remains unclear how general these cell principles are. Here, we examine the spatial organization of mitochondria within MIN6 pancreatic beta cells under variable glucose conditions. We observe glucose-dependent redistributions of mitochondria, favoring peripheral localization at elevated glucose levels when insulin secretion is also elevated. Our results suggest that active mitochondrial transport along microtubules and calcium activity, but not ATP synthesis, are critical regulators of this …
Predicting Sleep And Sleep Stage In Children Using Actigraphy And Heartrate Via A Long Short-Term Memory Deep Learning Algorithm: A Performance Evaluation, Robert Weaver Med, Phd, James White, Olivia Finnegan, Hongpeng Yang, Zifei Zhong, Keagan Kiely, Catherine Jones, Yan Tong, Srihari Nelakuditi, Rahul Ghosal, David E. Brown, Russell R. Pate Ph.D., Gregory J. Welk, Massimiliano De Zambotti, Yuan Wang, Sarah Burkart, Elizabeth L. Adams Phd, Bridget Armstrong, Michael Beets Med, Mph, Phd
Predicting Sleep And Sleep Stage In Children Using Actigraphy And Heartrate Via A Long Short-Term Memory Deep Learning Algorithm: A Performance Evaluation, Robert Weaver Med, Phd, James White, Olivia Finnegan, Hongpeng Yang, Zifei Zhong, Keagan Kiely, Catherine Jones, Yan Tong, Srihari Nelakuditi, Rahul Ghosal, David E. Brown, Russell R. Pate Ph.D., Gregory J. Welk, Massimiliano De Zambotti, Yuan Wang, Sarah Burkart, Elizabeth L. Adams Phd, Bridget Armstrong, Michael Beets Med, Mph, Phd
Faculty Publications
Children's ambulatory sleep is commonly measured via actigraphy. However, traditional actigraphy measured sleep (e.g., Sadeh algorithm) struggles to predict wake (i.e., specificity, values typically < 70) and cannot predict sleep stages. Long short-term memory (LSTM) is a machine learning algorithm that may address these deficiencies. This study evaluated the agreement of LSTM sleep estimates from actigraphy and heartrate (HR) data with polysomnography (PSG). Children (N = 238, 5–12 years,52.8% male, 50% Black 31.9% White) participated in an overnight laboratory polysomnography. Participants were referred be-cause of suspected sleep disruptions. Children wore an ActiGraph GT9X accelerometer and two of three consumer wearables(i.e., Apple Watch Series 7, Fitbit Sense, Garmin Vivoactive 4) on their non-dominant wrist during the polysomnogram. LSTM estimated sleep versus wake and sleep stage (wake, not-REM, REM) using raw actigraphy and HR data for each 30-s epoch. Logistic regression and random forest were also estimated as a benchmark for performance with which to compare the LSTM results. A 10-fold cross-validation technique was employed, and confusion matrices were constructed. Sensitivity and specificity were calculated to assess the agreement between research-grade and consumer wearables with the criterion polysomnography. For sleep versus wake classification, LSTM outperformed logistic regression and random forest with accuracy ranging from 94.1to 95.1, sensitivity ranging from 94.9 to 95.9 across different devices, and specificity ranging from 84.5 to 89.6. The addition of HR improved the prediction of sleep stages but not binary sleep versus wake. LSTM is promising for predicting sleep and sleep staging from actigraphy data, and HR may improve sleep stage prediction.
Re: Comment Letter For The Butte Priority Soils Operable Unit (Bpsou) 2022 Draft Final Insufficiently Reclaimed Sites Sampling Bres No. 30 – Atlantic 1 Site Evaluation Summary Report (Dated February 24, 2025), Molly Roby
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Post-Wildfire Erosion And Sedimentation: An Escalating Threat For Utah Fisheries, Colton James, Kendall Becker, Scott Hotaling, Aish Chandrasekaran, Alex Fiedler, Timothy E. Walsworth, Patrick Belmont
Post-Wildfire Erosion And Sedimentation: An Escalating Threat For Utah Fisheries, Colton James, Kendall Becker, Scott Hotaling, Aish Chandrasekaran, Alex Fiedler, Timothy E. Walsworth, Patrick Belmont
All Current Publications
Wildfires are a natural part of the western U.S. landscape and provide numerous benefits, including enhanced nutrient cycling and habitat rejuvenation. Utah’s fish populations evolved with wildfire as a common disturbance. However, the increasing size and severity of wildfires, combined with Utah’s heavily engineered and fragmented stream networks, pose a contemporary risk to fish populations. This fact sheet reviews wildfire impacts on erosion and Utah's watersheds and fisheries. It outlines measures we can take to prevent post-wildfire fish die-offs.
A Rapid Method For Identifying Plant Oxidative Stress And Implications For Riparian Vegetation Management, Mizanur Rahman, Takashi Asaeda, Kiyotaka Fukahori, Md Harun Rashid, Hideo Kawashima, Junichi Akimoto, Refah Tabassoom Anta
A Rapid Method For Identifying Plant Oxidative Stress And Implications For Riparian Vegetation Management, Mizanur Rahman, Takashi Asaeda, Kiyotaka Fukahori, Md Harun Rashid, Hideo Kawashima, Junichi Akimoto, Refah Tabassoom Anta
School of Earth, Environmental, & Marine Sciences Faculty Publications
Native and invasive plants of the riverain region undergo a range of environmental stresses that result in excess reactive oxygen species (ROS). Hydrogen peroxide (H2O2) is a relatively stable and quickly quantifiable way among different ROS. The herbaceous species including Artemisia princeps, Sicyos angulatus, and Solidago altissima were selected. The H2O2 and photosynthetic pigment of leaves were measured, soil samples were analyzed to quantify macronutrients such as total nitrogen (TN), total phosphorus (TP), and soil moisture, and photosynthetic photon flux density (PPFD) was also recorded at different observed sites of Arakawa Tarouemon, Japan. The H2O2 concentration of S. altissima significantly …
Spatiotemporal Responses To A Rural Highway By Four Mammal Species, Caitlin K. Brett, Anna Rose Mehner, John H. Young Jr., Sarah E. Lehnen, Richard J. Kline
Spatiotemporal Responses To A Rural Highway By Four Mammal Species, Caitlin K. Brett, Anna Rose Mehner, John H. Young Jr., Sarah E. Lehnen, Richard J. Kline
School of Earth, Environmental, & Marine Sciences Faculty Publications
Roads can negatively impact the wildlife communities they transect. Road mortalities from wildlife-vehicle collisions are one direct effect, but roads may also indirectly affect wildlife behavior, movement, or local distribution. Quantifying the spatial extent of these road-effects is important for understanding how roads indirectly affect species of concern, identifying potential sources of disturbance, and for estimating the effectiveness of road mitigation structures. Farm-to-Market Road (FM)106, which transects part of the Laguna Atascosa National Wildlife Refuge in Cameron County, Texas, has been identified as a potential source of wildlife road mortalities, particularly for one of the two remaining breeding populations of …
Synthesis Of Cancrinite Zeolite From Toraja Natural Bentonite For Heavy Metal Removal From Wastewater, Yuli Astuti, Paulina Taba, Siti Fauziah, Syarifuddin Liong, Yusafir Hala, Nur Umriani Permatasari, Satria Putra Jaya Negara, Fadliah Fadliah
Synthesis Of Cancrinite Zeolite From Toraja Natural Bentonite For Heavy Metal Removal From Wastewater, Yuli Astuti, Paulina Taba, Siti Fauziah, Syarifuddin Liong, Yusafir Hala, Nur Umriani Permatasari, Satria Putra Jaya Negara, Fadliah Fadliah
Karbala International Journal of Modern Science
This study explores the production of cancrinite (CAN) zeolite from bentonite found in Toraja (a place in South Sulawesi Province, Indonesia) and its effectiveness in removing Pb2+ and Fe3+ ions from wastewater. The synthesis was carried out using a hydrothermal method with varying NaOH concentrations, where a single phase of zeolite was formed at 5 M, as confirmed through XRD analysis. FTIR results showed the characteristics of CAN zeolite with typical absorption peaks at 676, 622, and 565 cm-1, as well as the presence of carbonate groups (CO₃2-) at 1300-1400 cm-1. SEM …
Machine Learning Crime Prediction Models And The Gap Between Research And Implementation: A Systematic Review, Ricardo Huamantingo, Miguel Cano-Lengua, Ciro Rodriguez
Machine Learning Crime Prediction Models And The Gap Between Research And Implementation: A Systematic Review, Ricardo Huamantingo, Miguel Cano-Lengua, Ciro Rodriguez
Karbala International Journal of Modern Science
A crime is an illegal or violent act committed by one individual against another. The increasing crime rate has become a major concern as it negatively affects people's quality of life and generates significant social and economic costs. This study aims to identify the most widely used machine learning (ML) models for crime prediction, determine evaluation metrics for assessing model performance, and analyze key data characteristics to enhance real-world implementation. The study follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology. A search string was formulated using the population, intervention, comparison, and outcomes (PICO) framework and applied …
Psilostachyin B As Potential Immune Checkpoint Inhibitor Targeting Ctla-4 And Pd-L1 In The Development Of Cancer Immunotherapy: A Computational Investigation, Moh Dliyauddin, Nabila Shafa Yumna Salsabila, Noviana Dwi Lestari, Sapti Puspitarini, Mansur Ibrahim, Sri Rahayu, Muhammad Sasmito Djati, Muhaimin Rifa’I
Psilostachyin B As Potential Immune Checkpoint Inhibitor Targeting Ctla-4 And Pd-L1 In The Development Of Cancer Immunotherapy: A Computational Investigation, Moh Dliyauddin, Nabila Shafa Yumna Salsabila, Noviana Dwi Lestari, Sapti Puspitarini, Mansur Ibrahim, Sri Rahayu, Muhammad Sasmito Djati, Muhaimin Rifa’I
Karbala International Journal of Modern Science
Immunotherapy is a promising treatment approach by targeting immune checkpoints such as CTLA-4 and PD-L1 to overcome cancer progression. The utilization of Curcuma longa and Phyllanthus niruri as potential immune checkpoint inhibitors offers an alternative cancer therapy. Computational analyses including molecular docking and molecular dynamics with validation using Molecular Mechanics/Poisson-Boltzmann Surface Area (MM-PBSA), Dynamic Cross-Correlation Matrix (DCCM), and Principal Component Analysis (PCA), were performed in this study. Results show that Psilostachyin B is the most promising inhibitor candidate against CTLA-4 and PD-L1, with binding affinity values of -6.9 and -6.8 kcal/mol, respectively. Molecular dynamics simulation results indicated that Psilostachyin B …
Leveraging Weekly Snow Cover Time Series For Improved Glacier Monitoring And Modeling, Rainey Aberle, Ellyn M. Enderlin, David R. Rounce, Shad O'Neel, Brandon Tober, Alexandra Friel
Leveraging Weekly Snow Cover Time Series For Improved Glacier Monitoring And Modeling, Rainey Aberle, Ellyn M. Enderlin, David R. Rounce, Shad O'Neel, Brandon Tober, Alexandra Friel
Boise State University Publications and Presentations
Seasonal snow and ice melt strongly influence glacier mass balance, yet sparse sub-annual observations limit our understanding of seasonal dynamics. Here we construct and analyze weekly snow cover time series for 200 glaciers across western North America from 2013 to 2023 using an automated image processing pipeline. Snow cover varied widely across the region: snow minima timing varied with latitude — from August from 62 to 64N to October from 48 to 50N—and accumulation area ratios ranged from near-zero to 0.92 (median of 0.52). A comparison of snowlines from observations and the PyGEM glacier mass balance model revealed seasonally evolving …
"...Anything My Friend Shares, I Would Want To Support Them By Clicking On It": Co-Designing Story-Based Interventions Against Clickbait For Teenagers, Ankit Shrestha, Audrey Flood, Bryson Hackler, Mahdi Nasrullah Al-Ameen
"...Anything My Friend Shares, I Would Want To Support Them By Clicking On It": Co-Designing Story-Based Interventions Against Clickbait For Teenagers, Ankit Shrestha, Audrey Flood, Bryson Hackler, Mahdi Nasrullah Al-Ameen
Computer Science Student Research
Teenagers' lack of digital sophistication and cyber hygiene makes them vulnerable to social engineering attacks, especially as they start using social media. Clickbait, one of such attacks, is primarily performed through social media to trick users into clicking on malicious links. With teenagers' increasing use of social media, clickbait poses a substantial threat to their online safety. The existing online safety measures for teens mainly focus on parental mediation, which can be perceived as restrictive and privacy-invasive. To this end, researchers recommended empowering teens to deal with online risks. In order to design such interventions for clickbait, we conducted co-design …
The People's Rivers: Early Environmental Regulation And The Oregon State Sanitary Authority, Avery Morgan Fischer
The People's Rivers: Early Environmental Regulation And The Oregon State Sanitary Authority, Avery Morgan Fischer
Dissertations and Theses
The environmental movement in Oregon can trace its origins to the turn of the twentieth century, where citizen activism and initiative led to the creation of an early environmental regulatory agency, the Oregon State Sanitary Authority. This creation established that the State of Oregon had a duty to preserve, not just the navigability or usability of rivers and waterways, but the quality and purity of its water. The Oregon State Sanitary Authority played an active role in maintaining and protecting the environment as a mandate of the people, and throughout its thirty-year existence battling industrial polluters, reluctant municipalities, and disinterested …