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Articles 1651 - 1680 of 64900
Full-Text Articles in Entire DC Network
A Robust Deep Learning Ensemble Framework For Waterbody Detection Using High-Resolution X-Band Sar Under Data-Constrained Conditions, Soyeon Choi, Seung Hee Kim, Son V. Nghiem, Menas Kafatos, Minha Choi, Jinsoo Kim, Yangwon Lee
A Robust Deep Learning Ensemble Framework For Waterbody Detection Using High-Resolution X-Band Sar Under Data-Constrained Conditions, Soyeon Choi, Seung Hee Kim, Son V. Nghiem, Menas Kafatos, Minha Choi, Jinsoo Kim, Yangwon Lee
Institute for ECHO Articles and Research
Accurate delineation of inland waterbodies is critical for applications such as hydrological monitoring, disaster response preparedness and response, and environmental management. While optical satellite imagery is hindered by cloud cover or low-light conditions, Synthetic Aperture Radar (SAR) provides consistent surface observations regardless of weather or illumination. This study introduces a deep learning-based ensemble framework for precise inland waterbody detection using high-resolution X-band Capella SAR imagery. To improve the discrimination of water from spectrally similar non-water surfaces (e.g., roads and urban structures), an 8-channel input configuration was developed by incorporating auxiliary geospatial features such as height above nearest drainage (HAND), slope, …
Reliability Of Approaches For Measuring Soil Organic Carbon And Implications For Results-Based Payments For Smallholder Carbon Farming, Friederike Schilling, Dennis Beesigamukama, Chrysantus M. Tanga
Reliability Of Approaches For Measuring Soil Organic Carbon And Implications For Results-Based Payments For Smallholder Carbon Farming, Friederike Schilling, Dennis Beesigamukama, Chrysantus M. Tanga
All Peer-Reviewed Publications
Soil organic carbon (SOC) measurement is critical for result-based payments for carbon sequestration in agriculture. This study examined (i) the consistency of SOC measurements from a portable near-infrared (NIR) spectroscopy soil scanner and laboratory analyses (Walkley-Black method) using samples from 151 plots across Western Kenya, and (ii) explored the implications of measurement error for SOC stock change estimates in group-based carbon farming schemes. Scanner predictions showed a weak correlation with laboratory results (R2 = 0.10–0.11; RMSE = 5.6–7.1 g/kg). Comparing results between the two laboratories showed only moderate agreement (R2 = 0.34) with a systematic bias of 7.5 …
From Uncertainty To Lucidity: Awareness Neutrosophic Kähler-Einstein Innovative Evaluator Methodological In Era Of Green Artificial Intelligence, Mona Mohamed, Ahmed M. Ali
From Uncertainty To Lucidity: Awareness Neutrosophic Kähler-Einstein Innovative Evaluator Methodological In Era Of Green Artificial Intelligence, Mona Mohamed, Ahmed M. Ali
Neutrosophic Systems with Applications
The rapid development of generative artificial intelligence (Gen AI) is a double-edged sword. On the positive side, Large Language Models (LLMs) of Gen AI as chatbot considered intelligent friend. Due to its potential to stimulate the maturation of ideas and cultivate fundamental general abilities like problem-solving and critical thinking. The advancement of Gen AI continued after that, moving from “chatbots” to “AI agents” that carry out multi-step activities in addition to responding to queries.
Regarding the downside, the terminology of “Red AI” era brought about by generative AI is marked by a performance at any expense that puts pressure on …
Stylespade: Realistic Image Augmentation For Robust Infrastructure Crack Segmentation Via Ensemble Learning, Jaeung Sim, Menas Kafatos, Seung Hee Kim, Yangwon Lee
Stylespade: Realistic Image Augmentation For Robust Infrastructure Crack Segmentation Via Ensemble Learning, Jaeung Sim, Menas Kafatos, Seung Hee Kim, Yangwon Lee
Institute for ECHO Articles and Research
The rapid deterioration of global infrastructure necessitates precise and automated crack detection technologies for proactive maintenance. However, deep learning-based segmentation models often suffer from a scarcity of diverse, high-quality labeled datasets. This study proposes StyleSPADE, a novel conditional image generation model that integrates semantic masks and style images to synthesize realistic crack data with diverse background textures while preserving precise geometric morphology. To validate the effectiveness of the generated data, we conducted extensive semantic segmentation tasks using Transformer-based (Mask2Former, Swin-UPerNet) and CNN-based (K-Net) models. Experimental results demonstrate that StyleSPADE-based augmentation significantly outperforms baseline models, achieving a Crack IoU of 0.6376 …
Protocol For The Development Of The Who Gestational Weight Gain Charts, Thais Rangel Bousquet Carrilho, Olufemi Taiwo Oladapo, Jennifer A. Hutcheon, Giovanna Gatica-Domínquez, Kathleen M. Rasmussen, Monica C. Flores-Urrutia, Richard Kumapley, Ӧzge Tunçalp, Dang Bahya-Batinda, Amel A. Fayed, Annick Bogaerts, Aris T. Papageorghiou, Cinthya Muñoz-Manrique, Dayana Rodrigues Farias, Eric Ohuma, Harshpal Sachdev, Hayfaa A. Wahabi, Helena J. Teede, Molin Wang, Nandita Perumal Phd
Protocol For The Development Of The Who Gestational Weight Gain Charts, Thais Rangel Bousquet Carrilho, Olufemi Taiwo Oladapo, Jennifer A. Hutcheon, Giovanna Gatica-Domínquez, Kathleen M. Rasmussen, Monica C. Flores-Urrutia, Richard Kumapley, Ӧzge Tunçalp, Dang Bahya-Batinda, Amel A. Fayed, Annick Bogaerts, Aris T. Papageorghiou, Cinthya Muñoz-Manrique, Dayana Rodrigues Farias, Eric Ohuma, Harshpal Sachdev, Hayfaa A. Wahabi, Helena J. Teede, Molin Wang, Nandita Perumal Phd
Faculty Publications
Introduction Gestational weight gain (GWG) is an important indicator of maternal nutrition to be monitored during pregnancy. However, there is no evidence-based tool that can be used to monitor it across all geographic locations and pre-pregnancy body mass index (BMI) categories. The WHO is undertaking a project to develop GWG charts by pre-pregnancy BMI category, and to identify GWG ranges associated with the lowest risks of adverse maternal and infant outcomes. This protocol describes all the steps that will be used to accomplish the development of these GWG charts.
Methods and analysis This project will involve the analysis of individual …
Developing Pattern Recognition And Interpretable Convolutional Neural Network Based Frameworks For Identifying Drug Resistant And Pan Cancer Mirnas From Expression Data, Joginder Jsingh
Doctoral Theses
Micro Ribonucleic Acids (miRNAs) are short length (∼24) non-coding RNAs and are considered as key biomarkers in cancer diagnosis and treatment. They play a vital role in classifying cancer patients from normal ones and drug resistant patients from control ones. The control patients are those who have not received any drug for cancer treatment. The objective is to identify a subset of miRNAs those help in the classification of the patients using expression data. The thesis is comprised of four contributory chapters in addition to an introduction and conclusion. In the first two contributory chapters, computational methods for ranking and …
Butte Medical Monitoring Working Group Meeting, Mike Mcanulty, Eric Hassler
Butte Medical Monitoring Working Group Meeting, Mike Mcanulty, Eric Hassler
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Determination Of Sample Size In Vaccine Trials, Meghna Bose
Determination Of Sample Size In Vaccine Trials, Meghna Bose
Doctoral Theses
Sample size determination is an important as well as delicate problem in clinical trials. Often, prior information available before the beginning of the trial is used to estimate the sample size. Hence, it is of importance to quantify the prior information available in terms of an Effective Sample Size (ESS). The problem of finding Effective Sample Size (ESS) in Phase II clinical trials, where toxicity and efficacy are the two components of the treatment response vector, is considered. In particular, one of the components is assumed to be binary, and the other is assumed to be continuous. Theoretical expressions for …
Assessing The Impact Of Visitors On Airborne Particle Deposition In The Giant Gypsum Geode Of Pulpí (Se Spain), Ana Camila Mendoza, Ángel Fernández-Cortés, Fernando Gázquez, Jesús Morilla, Milagros Carretero, Jose Maria Calaforra, David Benavente
Assessing The Impact Of Visitors On Airborne Particle Deposition In The Giant Gypsum Geode Of Pulpí (Se Spain), Ana Camila Mendoza, Ángel Fernández-Cortés, Fernando Gázquez, Jesús Morilla, Milagros Carretero, Jose Maria Calaforra, David Benavente
International Journal of Speleology
The Giant Geode of Pulpí is a unique mineralogical phenomenon worldwide, remarkable for its large selenite gypsum crystals. Its recent development as a tourist site and inclusion on UNESCO’s Tentative World Heritage List, highlight the need to assess the impact of visits on its conservation. This study investigates airborne particle dynamics inside the Geode, focusing on tourist activity and natural ventilation. We measured deposition rates and composition of airborne particles using passive traps and a continuous laser-optical particle counter. Microenvironmental variables linked to ventilation, such as temperature and radon gas concentration (²²²Rn), were simultaneously monitored. Results show a predominance of …
Environmental Degradations In Images: Analysis, Restoration, And Applications, Harsh Bhandari
Environmental Degradations In Images: Analysis, Restoration, And Applications, Harsh Bhandari
Doctoral Theses
This thesis investigates computational models and methodologies for restoring images degraded by challenging environmental conditions such as haze and underwater environments. It further explores the analysis and estimation of particulate matter (PM) concentration from both day and night scenes under varying weather conditions, using degraded visual data as a primary input. Each environment introduces distinct forms of visual degradation, making image restoration a critical challenge that directly impacts applications including visibility enhancement, weather analysis, particulate concentration estimation, and object detection. By addressing these challenges, this thesis aims to develop adaptable, data-driven solutions that enhance image clarity and improve information extraction …
Confluence, Vol. 4, Iss. 2, Full Issue
Evaluating Lunch Plan Data In The St. Charles School District (Scsd), Maddy Alexander, Guillermo Bilbao Olarreaga, Duncan Krige, Alyssa Schreiber, Nick Wintz, Wojciech Golik
Evaluating Lunch Plan Data In The St. Charles School District (Scsd), Maddy Alexander, Guillermo Bilbao Olarreaga, Duncan Krige, Alyssa Schreiber, Nick Wintz, Wojciech Golik
The Confluence
The SCSD is a public school district in St. Charles, with, on average, 4500 students a year. The SCSD is subdivided into an early childhood center, six elementary schools, two intermediate (5-6,7-8) schools, and two high schools. Vocational schools are also within this district but were not included in this report. The SCSD is concerned with the impact of the Covid-19 pandemic on their district’s population and on the number of students that needed assistance with lunch. They have asked Lindenwood’s 2024-25 PIC Math group to analyze their data from the years 2020-25 and identify any trends. Identifying these trends …
Contribution To The Chemotherapy Of Human Trypanosomiasis: Design, Synthesis, And Biological Evaluation Of Dimeric 2-Nitroimidazoles Against Trypanosoma Cruzi Amastigotes And Bloodstream Trypanosoma Brucei, Afonso Santine M.M. Velez, Otavio Augusto Chaves, Carlos Serpa, Fatma M. Salem, Bibo Li Ph.D., Bin Su Ph.D., Celio Geraldo Freire-De-Lima, Debra Decote-Ricardo, Marco Edilson Freire De Lima
Contribution To The Chemotherapy Of Human Trypanosomiasis: Design, Synthesis, And Biological Evaluation Of Dimeric 2-Nitroimidazoles Against Trypanosoma Cruzi Amastigotes And Bloodstream Trypanosoma Brucei, Afonso Santine M.M. Velez, Otavio Augusto Chaves, Carlos Serpa, Fatma M. Salem, Bibo Li Ph.D., Bin Su Ph.D., Celio Geraldo Freire-De-Lima, Debra Decote-Ricardo, Marco Edilson Freire De Lima
Biological, Geological, and Environmental Faculty Publications
Effective and safe treatments for neglected tropical diseases caused by parasites, such as Chagas disease and sleeping sickness, remain lacking, posing a significant challenge for researchers worldwide. The rational design of dimeric compounds inspired solely by the pharmacophoric core of benznidazole (2-nitroimidazole) has proven to be a promising strategy for antiparasitic development. Thus, in the present work, it was increased the linker between the active units (2-nitroimidazole) to improve the interaction with TcNTR, facilitating the bioactivation of the longest dimers. Biological assays confirmed this, demonstrating that all compounds were active against replicative intracellular amastigotes of Trypanosoma cruzi (Tulahuen C2C4-LacZ). Notably, …
Antibacterial Peptides From Soybean (Glycine Max (L.) Merr.) With In Silico Study Against Escherichia Coli Bacteria, Dian Riana Ningsih, Ely Setiawan, Purwati Purwati, Zusfahair Zusfahair, Anita Hindayanti Rukmana
Antibacterial Peptides From Soybean (Glycine Max (L.) Merr.) With In Silico Study Against Escherichia Coli Bacteria, Dian Riana Ningsih, Ely Setiawan, Purwati Purwati, Zusfahair Zusfahair, Anita Hindayanti Rukmana
Karbala International Journal of Modern Science
Bioactive peptides are produced from soy milk protein hydrolysis using trypsin. The research began with the preparation and separation of soy milk protein, followed by fractionation using ammonium sulphate, protein hydrolysis, and SDS-PAGE analysis of protein hydrolysates. Fractions exhibiting the highest degree of hydrolysis were further fractionated by SPE and tested to determine the antibacterial activity Staphylococcus aureus and Escherichia coli. The peptide sequence of the active peptide as an antibacterial was identified, employing LC-HRMS. The mode of action between active peptides and bacterial membran was analysed using molecular dynamics (MD) simulation. The findings displayed that F15 contained the highest …
Sociodemographic And Hiv-Related Characteristics Associated With Mental Health Diagnoses Among People Living With Hiv, Monique J. Brown Ph.D., Mph, Jiayang Xiao, Xueying Yang Ph.D., Bankole Olatosi Ph.D., Sharon Weissman, Xiaoming Li Ph.D., Jiajia Zhang Ph.D.
Sociodemographic And Hiv-Related Characteristics Associated With Mental Health Diagnoses Among People Living With Hiv, Monique J. Brown Ph.D., Mph, Jiayang Xiao, Xueying Yang Ph.D., Bankole Olatosi Ph.D., Sharon Weissman, Xiaoming Li Ph.D., Jiajia Zhang Ph.D.
Faculty Publications
Mental health diagnoses have been linked to poor HIV treatment outcomes and poorer quality of life among people living with HIV (PLWH). Therefore, this study aimed to investigate the association between sociodemographic and HIV-related characteristics, and common and serious mental health disorders among PLWH in South Carolina (SC). Data were obtained from the integrated system of statewide electronic health record (EHR) data in SC (2006–2019; N = 8,124). Multivariable logistic regression models were used to determine the associations between sociodemographic and HIV-related characteristics, and common mental health disorders and serious mental health disorders. Among the study population, 4% were 60 …
Butte Priority Soils Operable Unit (Bpsou) 2025 Monthly Progress Report. Consent Decree For The Butte Priority Soils Operable Unit. Civil Action No. Cv 89-039-Bu-Seh, Atlantic Richfield Company
Butte Priority Soils Operable Unit (Bpsou) 2025 Monthly Progress Report. Consent Decree For The Butte Priority Soils Operable Unit. Civil Action No. Cv 89-039-Bu-Seh, Atlantic Richfield Company
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Teaching Numeracy For Social Justice: Educational Equity, Esther Isabelle Wilder, Crystal C. Rodriguez, Caterina Shost, Eduardo Vianna, Frank Wang
Teaching Numeracy For Social Justice: Educational Equity, Esther Isabelle Wilder, Crystal C. Rodriguez, Caterina Shost, Eduardo Vianna, Frank Wang
Numeracy
The special collection, “Teaching Numeracy for Social Justice: Educational Equity,” focuses on how quantitative reasoning (QR) can function as a vehicle for equity, empowerment, and democratic participation. Building on a longstanding tradition that treats numeracy as inseparable from social justice, these contributions highlight how progressive pedagogies (e.g., active learning, authentic research, and equity-oriented assessment) have the potential to broaden access for students historically excluded from quantitative fields. The studies span a variety of conceptual frameworks, introductory and advanced quantitative instruction, and interdisciplinary applications, showcasing how inclusive QR practices can build confidence, agency, and real-world understanding. These articles demonstrate that when …
Utilizing Machine Learning Techniques For Computer-Aided Covid-19 Screening Based On Clinical Data, Honglun Xu, Andrews T. Anum, Michael Pokojovy, Sreenath Chalil Madathil, Yuxin Wen, Md. Fashiar Rahman, Tzu-Liang Bill Tseng, Scott Moen, Eric Walser
Utilizing Machine Learning Techniques For Computer-Aided Covid-19 Screening Based On Clinical Data, Honglun Xu, Andrews T. Anum, Michael Pokojovy, Sreenath Chalil Madathil, Yuxin Wen, Md. Fashiar Rahman, Tzu-Liang Bill Tseng, Scott Moen, Eric Walser
Engineering Faculty Articles and Research
The COVID-19 pandemic has highlighted the importance of rapid clinical decision-making to facilitate the efficient usage of healthcare resources. Over the past decade, machine learning (ML) has caused a tectonic shift in healthcare, empowering data-driven prediction and decision-making. Recent research demonstrates how ML was used to respond to the COVID-19 pandemic. This paper puts forth new computer-aided COVID-19 disease screening techniques using six classes of ML algorithms (including penalized logistic regression, random forest, artificial neural networks, and support vector machines) and evaluates their performance when applied to a real-world clinical dataset containing patients’ demographic information and vital indices (such as …
Combinatorial Synthesis Of Protein-Polymer Conjugates By Post-Polymerization Modification Of Poly(Pentafluorophenyl Acrylate)S, Emily W. Kish, Thatcher M. Lee, Alexis M. Ziemba, Ama Boamah, Bianca Figueroa, Margherita Piccardi, Carey E. Dougan, Sarah J. Moore, Maren E. Buck
Combinatorial Synthesis Of Protein-Polymer Conjugates By Post-Polymerization Modification Of Poly(Pentafluorophenyl Acrylate)S, Emily W. Kish, Thatcher M. Lee, Alexis M. Ziemba, Ama Boamah, Bianca Figueroa, Margherita Piccardi, Carey E. Dougan, Sarah J. Moore, Maren E. Buck
Chemistry: Faculty Publications
Combinatorial methods for preparing polymeric biomaterials enable the rapid identification of materials useful for many applications in science, medicine, and engineering. In the work described here, we demonstrate that side-chain reactive polymers can be used as templates for the rapid preparation of a small library of diversely functionalized protein–polymer conjugates. The activated ester polymer poly(pentafluorophenyl acrylate) (PPFPA) was modified postpolymerization with substoichiometric equivalents of three hydrophilic primary amines to yield a library of amphiphilic, side-chain reactive copolymers. These copolymers were then conjugated to two receptor-targeting proteins, holotransferrin (hTF) and an engineered fibronectin-based protein (Fn3), through amine-activated ester coupling. We investigated …
Optimized Resnet-18 Architecture For Multi-Class Oral Diseases Classification, Ahmed Ahmed
Optimized Resnet-18 Architecture For Multi-Class Oral Diseases Classification, Ahmed Ahmed
Karbala International Journal of Modern Science
In recent years, the classification of oral diseases has gained significant attention due to its influence on public health and the necessity for early and accurate diagnosis. Traditional diagnosis depends on manual clinical assessment, which can be slow and subjective. An optimized and subsequently quantized model is required to provide a faster and more consistent diagnostic support tool. This paper proposes an optimized ResNet-18 architecture for the classification of six oral diseases. The optimization process is based on removing the Rectified Linear Unit (ReLU), Batch Normalization (BN), and convolutional layers from the base ResNet-18 blocks that contain 128 filters. This …
Sperm-Associated Antigen 6 (Spag6) As A Potential Marker Of Sperm Function In Diagnosing Male Infertility, Ibtisam A. Al-Ali,, Kawkab A. Alsaadi
Sperm-Associated Antigen 6 (Spag6) As A Potential Marker Of Sperm Function In Diagnosing Male Infertility, Ibtisam A. Al-Ali,, Kawkab A. Alsaadi
Karbala International Journal of Modern Science
Background: While male infertility has become a significant global health concern, conventional analysis of semen has not made progress in the detection of contraindicated molecular biomarkers, such as sperm-associated antigen 6 (SPAG6), which is a protein involved in axonemal structure and flagellar motility.
Hypothesis: Expression of SPAG6 correlates with sperm motility and structural integrity. This means that its dysregulation may serve as a molecular indicator of impaired sperm performance.
Methods: A comprehensive review of recent studies was conducted with a focus on SPAG6’s molecular characteristics, expression patterns in normal versus abnormal spermatozoa, and the role it plays in motility-related …
Optimized Co2 Gas Sensing With Sns:Sm2o3/N-Si Nanocomposites Fabricated Via Spray Pyrolysis, Wasan A. Khalaf, Mays A. Hammadi, Mohammed J. Alsultani, Yahya R. Hathal, Mohammed O. Salman
Optimized Co2 Gas Sensing With Sns:Sm2o3/N-Si Nanocomposites Fabricated Via Spray Pyrolysis, Wasan A. Khalaf, Mays A. Hammadi, Mohammed J. Alsultani, Yahya R. Hathal, Mohammed O. Salman
Karbala International Journal of Modern Science
In this work, tin sulfide:samarium oxide (SnS:Sm2O3) composite films were deposited using a spray pyrolysis technique for room-temperature CO2 gas sensing. X-ray diffraction (XRD) confirmed a polycrystalline SnS nature of orthorhombic-phase crystallinity at 10 at.% Sm ions, while 20 at.% Sm induced Sm2O3 as a separate phase. Field emission-scanning electron microscopy (FE-SEM) induced uniform grains and increased the surface roughness, enhancing gas adsorption. UV-visible absorbance revealed band-gap narrowing. Fourier transform infrared spectroscopy (FTIR) analysis revealed vibrational band shifts, confirming the structural modifications. Gas-sensing measurements demonstrated 5.72%, 19.65%, and 9.65% for pure SnS, …
Re: Conditional Approval Letter For The Draft Final Butte Reduction Works (Brw) Smelter Area Mine Waste Remediation And Contaminated Groundwater Hydraulic Control Site Pre-Design Investigation (Pdi) Evaluation Report (Dated September 12, 2025), Emma Rott
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Re: Comment Letter For Draft Clark Tailings Consolidated Waste Management Area (Ctcwma) 2024 Data Summary Report (Dated October 15, 2025), Emma Rott
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Geophysical Analysis Of Volcanic Soils Influencing Microbial Habitat Dynamics On Taal Volcano Island, Ray Albert E. La Rosa, Iluminada A. Ronio, Shaun Michael C. Basco, Martin Gabriel Z. Dela Cruz
Geophysical Analysis Of Volcanic Soils Influencing Microbial Habitat Dynamics On Taal Volcano Island, Ray Albert E. La Rosa, Iluminada A. Ronio, Shaun Michael C. Basco, Martin Gabriel Z. Dela Cruz
The Lasallian Journal of Health
Taal Volcano Island in Batangas, Philippines, hosts an active post-caldera complex with a large hydrothermal system producing extreme soil environments. This study analyzed the geophysical and geochemical characteristics of shoreline soils to determine their potential as microbial habitats. Soil samples were collected at 14°02′04″N, 121°00′09″E, one meter below the surface of near newly formed vents. Physical parameters, including water content, bulk density, sedimentation, texture, and porosity, were measured alongside pH and temperature data. Results revealed sandy soil texture with 25% moisture, moderate compaction (1.66 g cm⁻³), high surface temperature (50 °C on-site; 72.7 °C PHIVOLCS data), and extreme acidity (pH …
Bridging The Gap: A Systematic Review Of Cyber Conflict Forecasting Models And The Case For Ai-Driven Dynamic Frameworks, Salim Arfaoui, Youssef Harrath, Omar El-Gayar
Bridging The Gap: A Systematic Review Of Cyber Conflict Forecasting Models And The Case For Ai-Driven Dynamic Frameworks, Salim Arfaoui, Youssef Harrath, Omar El-Gayar
Research & Publications
Cyber conflict forecasting remains constrained by static models that overlook the integration of geopolitical context with technical indicators. This systematic literature review examines 58 studies (2010–2025) using PRISMA guidelines and an InputProcess-Output framework to classify approaches and identify key gaps. Quantitative methods dominate (67%), yet only 14% incorporate geopolitical variables, despite the political nature of cyber conflict. Major limitations include adversarial adaptation blindness (85% assume static behavior), coarse temporal granularity (72% use daily+ intervals), lack of uncertainty quantification (75%), and minimal modeling of cross-domain escalation (92% cyber-only focus). Strategic forecasting is rare, with just 14% providing long-term insights and 16% …
High Spatiotemporal Resolution Monitoring Of Crop Water Stress Across The Contiguous United States Using Harmonized Landsat And Sentinel-2 Data, Na Chen, Yanlei Feng, Na Wang, Jevan Yu, Mohammad Reza Alizadeh, Yifeng Cui, Ning Ye, Wenzhe Jiao, Joshua B. Fisher, César Terrer
High Spatiotemporal Resolution Monitoring Of Crop Water Stress Across The Contiguous United States Using Harmonized Landsat And Sentinel-2 Data, Na Chen, Yanlei Feng, Na Wang, Jevan Yu, Mohammad Reza Alizadeh, Yifeng Cui, Ning Ye, Wenzhe Jiao, Joshua B. Fisher, César Terrer
Biology, Chemistry, and Environmental Sciences Faculty Articles and Research
Accurate and timely monitoring of crop water stress is essential for efficient agricultural water management, ultimately maintaining and improving crop productivity. While Landsat has been used for this purpose, its temporal resolution hampers timely detection of crop water stress. The recently released Harmonized Landsat and Sentinel-2 Version 2.0 dataset, which enables a higher-frequency time series of satellite observations (2–3 days, 30 m), offers a promising solution to this challenge. However, its potential for crop stress monitoring remained unexplored. In this study, we utilized 923 HLS satellite tiles to assess crop water stress across the contiguous United States (CONUS). Crop water …
Multiple Myeloma Risk Linked To Dna Damage Response Genes, Michael Conry, Irina Ostrovnaya, Yelena Kemel, Saloni Sinha, Linda B. Baughn, Brian Avery, Kylee Maclachlan, Victoria Groner, Lauren Banaszak, Aaron Norman, Nicholas J. Boddicker, Alyssa I. Clay-Gilmour Ph.D., Shaji Kumar, Ellen Kim, Sita Dandiker, Mitul Waghmare, Susan Slager, Douglas Sborov, Judy Garber, Elizabeth E. Brown, Michelle Hildebrandt, Et. Al.
Multiple Myeloma Risk Linked To Dna Damage Response Genes, Michael Conry, Irina Ostrovnaya, Yelena Kemel, Saloni Sinha, Linda B. Baughn, Brian Avery, Kylee Maclachlan, Victoria Groner, Lauren Banaszak, Aaron Norman, Nicholas J. Boddicker, Alyssa I. Clay-Gilmour Ph.D., Shaji Kumar, Ellen Kim, Sita Dandiker, Mitul Waghmare, Susan Slager, Douglas Sborov, Judy Garber, Elizabeth E. Brown, Michelle Hildebrandt, Et. Al.
Faculty Publications
Background DNA damage response genes (DDRG), implicated in several cancers as both predisposing risk factors as well as biomarkers for aggressiveness, have not been fully explored in multiple myeloma (MM).
Methods Herein, we analyzed disease associations of pathogenic variations in nine putative candidate genes using 3 446 MM cases and 323 233 cancer-free controls.
Results Increased MM risk was found to be associated with inherited rare pathogenic mutations in TP53, ATM, CHEK2, KDM1A, and ARID1A, with an enrichment of these variants among individuals with early onset or family history of MM. Individuals with TP53 or ATM germline mutations are also …
Thermal Performance And Specific Energy Consumption Of Traditional Tobacco Curing Barns In Tanzania, Seuri S. Kilakoi, Baraka Kichonge, Thomas Kivevele, Mtaki T. Maagi, Jacob B. Lisuma
Thermal Performance And Specific Energy Consumption Of Traditional Tobacco Curing Barns In Tanzania, Seuri S. Kilakoi, Baraka Kichonge, Thomas Kivevele, Mtaki T. Maagi, Jacob B. Lisuma
Tanzania Journal of Science
Traditional tobacco curing barns remain the dominant technology in Tanzania due to their low construction cost and accessibility, particularly in major producing regions such as Tabora. However, their thermal inefficiency results in excessive firewood use and environmental degradation. This study presents a field-based performance evaluation of a traditional flue-curing barn at the Tobacco Research Institute of Tanzania. Environmental parameters and fuel consumption were monitored at 15- minute intervals throughout the yellowing, leaf drying, and stem drying stages. The curing process handled 429 kg of fresh tobacco using 1,016 kg of firewood, equivalent to 16,256 MJ of energy input. The specific …
A Phase 1, First-In-Human, Dose Escalation Study Of Jnj-80038114, A Psmaxcd3 Bispecific Antibody, In Participants With Metastatic Castration-Resistant Prostate Cancer, Andrew Hudson, Anuradha Jayaram, Benjamin Garmezy, Nicholas Zorko, Kevin Zarrabi, Ligi Mathews, Brent Rupnow, Mengjie Li, Debopriya Ghosh, Karen Urtishak, Peter Francis, Sherry Wang, Edward Attiyeh, Johann De Bono
A Phase 1, First-In-Human, Dose Escalation Study Of Jnj-80038114, A Psmaxcd3 Bispecific Antibody, In Participants With Metastatic Castration-Resistant Prostate Cancer, Andrew Hudson, Anuradha Jayaram, Benjamin Garmezy, Nicholas Zorko, Kevin Zarrabi, Ligi Mathews, Brent Rupnow, Mengjie Li, Debopriya Ghosh, Karen Urtishak, Peter Francis, Sherry Wang, Edward Attiyeh, Johann De Bono
Department of Medical Oncology Faculty Papers
PURPOSE: Prostate-specific membrane antigen (PSMA) has been identified as a therapeutic target for metastatic castration-resistant prostate cancer (mCRPC). The recent success of radioligands targeting PSMA spurred development of new PSMA-targeting agents including immunotherapy. JNJ-80038114 is a bispecific antibody that binds PSMA on tumor cells and CD3 on T cells to induce anti-tumor activity.
METHODS: This was a phase 1, open-label, multicenter study of JNJ-80038114 in participants with mCRPC and ≥ 1 prior systemic therapy. JNJ-80038114 was administered subcutaneously every 3 weeks (Q3W), starting at 0.1 mg. The primary endpoint was safety. Secondary endpoints included pharmacokinetics (PK), immunogenicity, and prostate-specific antigen …