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Articles 631 - 660 of 6419
Full-Text Articles in Entire DC Network
Comparing Fermented Food And Vitamin E On Exercise-Mediated Nrf2/Are Activation In Middle-Aged/ Elderly: A Randomized, Double-Blind Clinical Study, Joseph Cervi, Reza Rastmanesh, Amir Moghadam-Ahmadi, Antonio Ayala, Cristiana Aperio, Aldo Lorenzetti, Maki Osato, Francesco Marotta, Antonio Nardin, Fang He
Comparing Fermented Food And Vitamin E On Exercise-Mediated Nrf2/Are Activation In Middle-Aged/ Elderly: A Randomized, Double-Blind Clinical Study, Joseph Cervi, Reza Rastmanesh, Amir Moghadam-Ahmadi, Antonio Ayala, Cristiana Aperio, Aldo Lorenzetti, Maki Osato, Francesco Marotta, Antonio Nardin, Fang He
Department of Neuroscience Faculty Papers
Background: There is a compelling need to emphasize the importance of deepening the rationale behind functional foods research in molecular biology. Indeed, establishing stringent criteria to evaluate functional food interventions in disease prevention and as adjunctive therapeutic strategies offers significant opportunities for health promotion. Objective: This study investigated the effects of fermented papaya preparation (FPP®) and vitamin E on gene expression in middle-aged/elderly individuals, leveraging FPP’s established antioxidant and immune-regulatory benefits. Methods: Graded Exercise Walking Test was administered twice weekly for 6 months. Total Antioxidant capacity (TAC) and gene expression (Nrf2, NQO1, HO-1) in PBMC were measured monthly. Results: Throughout …
Protein Consumption And Risk Of Cvd Among Us Adults: The Multi-Ethnic Study Of Atherosclerosis (Mesa), Ji Yun Tark, Ruosha Li, Bing Yu, Alexis C Wood, Nikhil S Padhye, Marcia C De Oliveira Otto
Protein Consumption And Risk Of Cvd Among Us Adults: The Multi-Ethnic Study Of Atherosclerosis (Mesa), Ji Yun Tark, Ruosha Li, Bing Yu, Alexis C Wood, Nikhil S Padhye, Marcia C De Oliveira Otto
Faculty, Staff and Students Publications
BACKGROUND: Although some randomized trials have reported beneficial effects of protein intake on cardiometabolic risk factors, evidence from prospective studies have not supported a strong link between protein intake and cardiovascular disease (CVD) risk. It is also unclear whether diversity in protein intake plays a role in CVD risk.
OBJECTIVE: We investigated prospective associations of (1) protein intake, overall and by food source and (2) diversity of protein sources with risk of CVD, coronary heart disease (CHD), and stroke.
METHODS: In a multi-ethnic cohort of 5879 U.S. adults (45-84 years), who were free of CVD at baseline, protein intake was …
Metabolites Link Intake Of A Healthy Diet To Better Insulin And Glucose Homeostasis In The Microbiome And Insulin Longitudinal Evaluation Study (Miles), Alexis C Wood, Danielle J Lee, Patricia A Sheridan, Elizabeth T Jensen, Gautam Ramesh, Alain G Bertoni, Stephen S Rich, Yii-Der I Chen, David M Herrington, Jerome I Rotter, Mark O Goodarzi
Metabolites Link Intake Of A Healthy Diet To Better Insulin And Glucose Homeostasis In The Microbiome And Insulin Longitudinal Evaluation Study (Miles), Alexis C Wood, Danielle J Lee, Patricia A Sheridan, Elizabeth T Jensen, Gautam Ramesh, Alain G Bertoni, Stephen S Rich, Yii-Der I Chen, David M Herrington, Jerome I Rotter, Mark O Goodarzi
Faculty, Staff and Students Publications
BACKGROUND: Dietary quality has been linked to better glycemic control, but the precise molecular mechanisms giving rise to these associations are not fully understood.
OBJECTIVES: To examine the association of metabolites associated with the intake of a healthy diet with measures of insulin/glucose homeostasis.
METHODS: Using cross-sectional data from 295 United States adults, the associations between 3 diet pattern scores and metabolome-wide metabolites were estimated via linear regression models, which controlled for demographic factors and health behaviors. Subsequently, the associations between the diet-related metabolites with 6 measures of glucose/insulin homeostasis were examined in similar models. A Bonferroni correction was applied …
Fetal Sex Effects On Maternal Health Can Now Be Tested Via Randomization: A First-In-Class Illustration In Cows On Glucoregulatory Outcomes, Aridany Suarez-Trujillo, Colby J Vorland, Griffin T Nicholls, Daniella E Chusyd, Chelsie Parker, Lilian Golzarri-Arroyo, Sophia Swann, Bethany J Funnell, Kara R Stewart, David B Allison
Fetal Sex Effects On Maternal Health Can Now Be Tested Via Randomization: A First-In-Class Illustration In Cows On Glucoregulatory Outcomes, Aridany Suarez-Trujillo, Colby J Vorland, Griffin T Nicholls, Daniella E Chusyd, Chelsie Parker, Lilian Golzarri-Arroyo, Sophia Swann, Bethany J Funnell, Kara R Stewart, David B Allison
Children’s Nutrition Research Center Staff Publications
Background: The maternal-offspring relationship, such as whether fetal sex influences maternal health, is essential to explore to advance prenatal and maternal health. While associations exist between fetal sex and maternal health outcomes, it is unclear whether these reflect a causal relationship.
Objective: To demonstrate that fetal sex can be randomly assigned to test the causal effect of fetal sex on maternal outcomes.
Methods: Holstein dairy cows were stratified and randomized using sealed opaque envelopes to be artificially inseminated with either X- or Y-sorted bull semen until 40 cows became pregnant. Monthly body weight measurements were recorded, and an intravenous glucose …
Avulsion Of The Flexor Digitorum Profundus Tendon During The Curettage Of A Recurrent Enchondroma: A Case Report, Shunpei Hama, Masataka Yasuda, Makoto Fukuda, Katsuaki Onishi, Takaaki Chikugo
Avulsion Of The Flexor Digitorum Profundus Tendon During The Curettage Of A Recurrent Enchondroma: A Case Report, Shunpei Hama, Masataka Yasuda, Makoto Fukuda, Katsuaki Onishi, Takaaki Chikugo
Children’s Nutrition Research Center Staff Publications
Enchondroma rarely occurs in the distal phalanx, and avulsion of the flexor digitorum profundus (FDP) tendon in this area is also rare. We report a case of recurrent enchondroma in the distal phalanx, which required reconstruction for an accidental FDP avulsion during surgery. A 36-year-old right-handed woman visited our hospital with a suspected recurrence of enchondroma and a planned surgery. Radiographs and computed tomography revealed three translucent lesions in the distal phalanx of her left index finger. We performed curettage and calcium phosphate bone cement (CPC) grafting. During the procedure, an avulsion of the FDP tendon was found. We reattached …
The United Arab Emirates Birth Cohort Study: A Pilot Examination Of Maternal And Infant Health Outcomes, Sharon Mutare
The United Arab Emirates Birth Cohort Study: A Pilot Examination Of Maternal And Infant Health Outcomes, Sharon Mutare
Dissertations
The first 1,000 days of life represent a critical window for influencing optimal fetal growth and establishing lifelong health foundations. Recent evidence underscores the significant association between maternal health and nutrition during this period and the subsequent risk of non-communicable diseases, which are responsible for 74% of global deaths. Despite the rapid globalization and urbanization experienced in the United Arab Emirates in recent years, there remains a paucity of research on how maternal health and nutrition impact perinatal outcomes among Emirati women.
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Food Neophobia, Food Pickiness, And Physical Growth Status In A Sample Of Emirati Children With Neurodevelopmental Disorders And Neurotypical Development In The United Arab Emirates, Hessa Salem Al Derei
Food Neophobia, Food Pickiness, And Physical Growth Status In A Sample Of Emirati Children With Neurodevelopmental Disorders And Neurotypical Development In The United Arab Emirates, Hessa Salem Al Derei
Theses
Eating habits and expression of independence in food selection typically starts at about 18 months of age, reaching its peak between 2 and 6 years. However, child feeding problems are common in boys and girls, both- in children with neuro-typical development (NTD) and those with neuro-development disorders (NDDs). Food Neophobia (FN) and Food Pickiness (FP) are considered as the main forms of food rejection in children, affecting their diet variety, and consumption of foods. If unresolved, these may result in nutrient deficiencies and compromised growth and development in children. There is a dearth of evidence on this important topic in …
The Association Between Food Production, Food Security, Household Consumer Behaviour And Waist-Hip Ratio Amongst Women In Smallholder Farming Households In Kilifi County, Kenya, Rosebella Iseme, Eunice Muthoni, Roselyter Riang’A, Felix Agoi, Noveline Khatievi, James Orwa, Beatrice Karembo Karisa, Bibi Abdallah Bakari, Morris Ogero, Mwanamaka Mabruki, Cyprian Mostert, Anthony Ngugi
The Association Between Food Production, Food Security, Household Consumer Behaviour And Waist-Hip Ratio Amongst Women In Smallholder Farming Households In Kilifi County, Kenya, Rosebella Iseme, Eunice Muthoni, Roselyter Riang’A, Felix Agoi, Noveline Khatievi, James Orwa, Beatrice Karembo Karisa, Bibi Abdallah Bakari, Morris Ogero, Mwanamaka Mabruki, Cyprian Mostert, Anthony Ngugi
Population Health, East Africa
Food insecurity disproportionately affects smallholder farming households and within them women, who bear primary caregiving responsibilities and contend with time and resource constraints that heighten their vulnerability to adverse nutrition-related health outcomes. This study cross-sectionally investigates the association between food production practices, household consumer behaviour, and the experience of food insecurity with women's waist-hip ratio (WHR), a key indicator of abdominal obesity, in a coastal community in Kenya. In total, 394 households were randomly selected from a list of farming households in Kaloleni and Rabai sub-counties of Kilifi. Trained enumerators administered questionnaires to adult female family members who play a …
Socio-Demographic Disparities In Diet Quality Among Utah Residents, Palak Gupta, Lendel K. Narine
Socio-Demographic Disparities In Diet Quality Among Utah Residents, Palak Gupta, Lendel K. Narine
Transforming Communities
Diet quality significantly influences health outcomes, with socio-demographic factors playing a crucial role in shaping dietary behaviors. This study aims to investigate the dietary behaviors and socio-demographic characteristics of Utah residents, highlighting disparities in diet quality and the underlying factors contributing to these differences. Using a sample of 1,522 adults, data on socio-demographic characteristics, diet quality, and food expenditure were collected via an online survey in April and May 2023. The modified Rapid Eating Assessment for Participants-Shortened Version (REAP-S) was used to assess diet quality. Results indicate that respondents spent about 30% of their monthly income on food, reflecting a …
The Relationship Of Dietary Pattern And Physical Activity On Cholesterol Level In Young Adults, Wahyuni Sammeng
The Relationship Of Dietary Pattern And Physical Activity On Cholesterol Level In Young Adults, Wahyuni Sammeng
Indonesian Journal of Public Health Nutrition (IJPHN)
High blood cholesterol levels are a serious problem because they are one of the risk factors for degenerative diseases such as cardiovascular. Research data shows that in Ambon City, 32.49% of the population has the habit of consuming fatty/cholesterol/fried foods ≥1 time per day. The purpose of this study was to determine the relationship between dietary habit and physical activity with blood cholesterol levels. The type of research used was quantitative, sampling technique used was convenience sampling for 30 people. The independent variables in this study were dietary intake (amount, frequency, and type) measured using a semi-quantitative FFQ and physical …
Different Food Coping Strategies In Urban And Semi-Urban Areas During Coronavirus Disease 2019 (Covid-19) Pandemic, Sandra Fikawati, Ahmad Syafiq, Rizna Notarianti, Syilga Cahya Gemily
Different Food Coping Strategies In Urban And Semi-Urban Areas During Coronavirus Disease 2019 (Covid-19) Pandemic, Sandra Fikawati, Ahmad Syafiq, Rizna Notarianti, Syilga Cahya Gemily
Indonesian Journal of Public Health Nutrition (IJPHN)
Consumption-related behavior implemented as an effort to maintain household food security is referred to as a food coping strategy (FCS). This study aims to describe the selection of FCS by families in urban and semi-urban areas in Indonesia during the COVID-19 pandemic. This research is a cross-sectional study with a total sample of 517 people who live in urban (Jakarta) and semi-urban (Depok) areas. The research data was taken from primary research data that had been collected online and purposively through Posyandu cadres who had access to family/community in October-December 2020. Data analysis used the chi-square test and multiple logistic …
The Effect Of Giving Calliandra Honey Water On Increasing Vo2max In Soccer Athletes, Masako Christina, Diah Mulyawati Utari
The Effect Of Giving Calliandra Honey Water On Increasing Vo2max In Soccer Athletes, Masako Christina, Diah Mulyawati Utari
Indonesian Journal of Public Health Nutrition (IJPHN)
Soccer athletes need to have good cardiorespiratory endurance because they are required to move from one place to another in order to keep up with opponents who move with or without the ball. However, in 2020, the majority (47%) of teenage athletes in game sports had VO2max score in the lower category. VO2max is used as the gold standard in determining a person's cardiorespiratory endurance. The higher the VO2max value, the better a person's cardiorespiratory endurance. This study aims to determine the relationship of consumption of calliandra honey water and VO2max value in soccer athletes in PPOP DKI Jakarta Province …
Factors Influencing Iron Intake Among Female Students In Universitas Indonesia, Kristina Adjie, Triyanti Triyanti
Factors Influencing Iron Intake Among Female Students In Universitas Indonesia, Kristina Adjie, Triyanti Triyanti
Indonesian Journal of Public Health Nutrition (IJPHN)
This study aims to determine the differences in iron intake among female college students based on consumption factors (animal-based side dishes, plant-based side dishes, vegetables, fruits, Ultra Processed Food) and individual factors (attitude towards red meat consumption, social media influence, nutrition knowledge, allowance, type of residence). The design of this study is cross-sectional, involving 147 undergraduate regular students from the Faculty of Public Health class of 2021, 2022, and 2023. Respondents were selected based on simple random sampling, and data collection was conducted online using Zoom. The research questionnaire was administered using Google Forms and Spreadsheets for the Semi Quantitative …
The Relationship Between Snacking And Sugar, Salt, Fat Intake On Nutritional Status Of Adolescents Of Smkn 30 Jakarta, Khoirul Anwar, Syifa Aulia Putri
The Relationship Between Snacking And Sugar, Salt, Fat Intake On Nutritional Status Of Adolescents Of Smkn 30 Jakarta, Khoirul Anwar, Syifa Aulia Putri
Indonesian Journal of Public Health Nutrition (IJPHN)
Excessive consumption of sugar, salt, and fat including from snacks can increase the risk of obesity or being overweight. The objective of this study to analyze the relationship between snacking and sugar, salt, and fat intake on nutritional status in adolescents. This design is cross-sectional with a sample of 90 grade X students at SMKN 30 Jakarta. The data collected include physical activity data using the Global Physical Activity Questionnaire (GPAQ), snacking habit data, frequency of sugar, salt, and fat consumption using the SQ-FFQ. The results of the correlation test showed that there was a significant relationship between snacking habits …
Factors Related To The Consumption Of Sugar-Sweetened Beverages (Ssbs) Among High School Students At Sma Negeri 68 Jakarta In 2024, Debora Karyoko, Wahyu Kurnia Yusrin Putra, Teguh Jati Prasetyo
Factors Related To The Consumption Of Sugar-Sweetened Beverages (Ssbs) Among High School Students At Sma Negeri 68 Jakarta In 2024, Debora Karyoko, Wahyu Kurnia Yusrin Putra, Teguh Jati Prasetyo
Indonesian Journal of Public Health Nutrition (IJPHN)
Indonesia ranked third in Southeast Asia for Sugar-Sweetened Beverages (SSBs) consumption in 2022, with a consumption rate of 20.23 liters/person/year. According to Riskesdas in 2018, 61.3% of the Indonesian population consumed more than once a day and 47.5% in 2023. This study aims to understand the patterns and levels of SSB consumption among various factors in students of SMA Negeri 68 Jakarta in 2024. This cross-sectional study was conducted from April to May 2024 with 134 respondents using questionnaires and interviews for 24-hour food recall and SQ-FFQ. Univariate analysis showed that 12.69% of respondents had high SSB consumption. Bivariate analysis …
Child Risk For Obesity And Physical Activity, Bethany Moore
Child Risk For Obesity And Physical Activity, Bethany Moore
All ETDs from UAB
Childhood obesity is a significant health problem in the United States with consequences presenting themselves in the short- and long-term. Physical activity is a modifiable factor associated with adiposity and can at least partially attenuate the consequences of childhood obesity. There are many factors which influence children’s participation in regular physical activity, some of which are also associated with pediatric obesity. The overarching purpose of this research is to investigate potential influences on the association of obesity and physical activity among typically developing children. Aim 1 used a secondary analysis of n=163 children to explore independent and interactive effects of …
Reproduction Has Immediate Effects On Female Mortality, But No Discernible Lasting Physiological Impacts: A Test Of The Disposable Soma Theory, Sharon E Mitchell, Megan Simpson, Lena Coulet, Solenn Gouedard, Catherine Hambly, Juliano Morimoto, David B Allison, John R Speakman
Reproduction Has Immediate Effects On Female Mortality, But No Discernible Lasting Physiological Impacts: A Test Of The Disposable Soma Theory, Sharon E Mitchell, Megan Simpson, Lena Coulet, Solenn Gouedard, Catherine Hambly, Juliano Morimoto, David B Allison, John R Speakman
Children’s Nutrition Research Center Staff Publications
The disposable soma theory (DST) posits that organisms age and die because of a direct trade-off in resource allocation between reproduction and somatic maintenance. DST predicts that investments in reproduction accentuate somatic damage which increase senescence and shortens lifespan. Here, we directly tested DST predictions in breeding and nonbreeding female C57BL/6J mice. We measured reproductive outputs, body composition, daily energy expenditure, and oxidative stress at peak lactation and over lifetime. We found that reproduction had an immediate and negative effect on survival due to problems encountered during parturition for some females. However, there was no statistically significant residual effect on …
Shell Translucency: A Novel Eggshell Quality Parameter In Broiler Breeders, Duarte Neves, Austin Jasek, Colwayne Morris, Raquel Burin, Kevin Stephens, Marco Rebollo
Shell Translucency: A Novel Eggshell Quality Parameter In Broiler Breeders, Duarte Neves, Austin Jasek, Colwayne Morris, Raquel Burin, Kevin Stephens, Marco Rebollo
Proceedings of the Arkansas Nutrition Conference
In the United States, nearly 240 million commercial broiler breeder eggs are incubated weekly with an average hatchability of 79.1% (Third Party Reporting). Between 160 eggs/hen and 125 chicks/hen the loss is considerable. In 2007, an estimated 1% improvement in hatchability would escalate profits by over $25 million to hatcheries and markedly increase profitability in broiler operations (Schaal and Gherian, 2007). In order to tap into top hatchability performances, egg management in commercial hatcheries such as egg storage time and conditions, incubation temperature and humidity, as well as turning frequency are of utmost importance (Vick et al., 1993; Reis et …
The Role Of Lymph-Adipose Crosstalk In Alcohol-Induced Perilymphatic Adipose Tissue Dysfunction, Kourtney D. Weaver, Liz Simon, Patricia E. Molina, Flavia Souza-Smith
The Role Of Lymph-Adipose Crosstalk In Alcohol-Induced Perilymphatic Adipose Tissue Dysfunction, Kourtney D. Weaver, Liz Simon, Patricia E. Molina, Flavia Souza-Smith
School of Graduate Studies Faculty Publications
Chronic alcohol use leads to metabolic dysfunction in adipose tissue. The underlying mechanisms and the contribution of alcohol-induced adipose tissue dysfunction to systemic metabolic dysregulation are not well understood. In our previous studies, we found that chronic alcohol feeding induces mesenteric lymphatic leakage, perilymphatic adipose tissue (PLAT) inflammation, and local insulin resistance in rats. The goal of this study was to further explore the link between alcohol-induced lymphatic leakage and PLAT immunometabolic dysregulation, locally and systemically, using in vivo and ex vivo approaches. Male rats received a Lieber–DeCarli liquid diet, of which 36% of the calories were from alcohol, for …
Teachers’ Perceptions Of An Integrated Nutrition Education Curriculum And The Impact On Preschoolers' Food Liking, Alicia Stapp, Laurel Lambert, Georgianna Mann, Kaitlyn Sills, Kenya Wolff
Teachers’ Perceptions Of An Integrated Nutrition Education Curriculum And The Impact On Preschoolers' Food Liking, Alicia Stapp, Laurel Lambert, Georgianna Mann, Kaitlyn Sills, Kenya Wolff
Journal of Public Health in the Deep South
Background: Nutrition education during early childhood that includes experiential learning, modeling, and family engagement can support lifelong healthy eating habits.
Purpose: The present study examined the impact of a nutrition-integrated, 32-week supplemental curriculum entitled Growing Healthy Minds, Bodies, and Communities on children’s exposure to fruits and vegetables, ability to identify fruits and vegetables, liking of fruit and vegetables, and teachers’ perceptions of the curriculum.
Methods: A pre- and post- fruit and vegetable pictorial Likert survey was administered to 261 Pre-K4 children. To investigate teachers’ perceptions of the curriculum, a post-intervention focus group was conducted with 19 teachers.
Results: Significant differences …
Health Matters! Coloring And Activity Book (80-Pages), Your Very Favorite, Children's Health, Lorraine Sheldon, May Bressler
Health Matters! Coloring And Activity Book (80-Pages), Your Very Favorite, Children's Health, Lorraine Sheldon, May Bressler
English
Health Matters! is a English-language health literacy resource designed for pediatric patients and their families. Written at an approximately 6th-grade reading level, it supports patient education through engaging coloring and activity pages.
The content covers a wide range of health and wellness topics, including body systems, nutrition, mental wellness, patient safety, and social-emotional skills such as building friendships and navigating conversations when returning to school. Developed for use in both hospital settings and the broader community, the resource promotes learning through interactive, age-appropriate activities.
This printable PDF version contains the complete collection of activities and comprises 80 pages. The resource …
Supporting African Communities To Increase Resilience And Mental Health Of Kids With Developmental Disabilities And Their Caregivers Using The World Health Organization’S Caregiver Skills Training Programme (Spark Trial): Study Protocol For A Cluster Randomised Clinical Controlled Trial, Melissa Nortey, Vibian Angweny, Beatrice Mkubwa, Rosa Hoekstra, Andrew Healey, Rahel Birhane, Nadine Seward, Temesgen Azmeraw, Fikite Girma
Supporting African Communities To Increase Resilience And Mental Health Of Kids With Developmental Disabilities And Their Caregivers Using The World Health Organization’S Caregiver Skills Training Programme (Spark Trial): Study Protocol For A Cluster Randomised Clinical Controlled Trial, Melissa Nortey, Vibian Angweny, Beatrice Mkubwa, Rosa Hoekstra, Andrew Healey, Rahel Birhane, Nadine Seward, Temesgen Azmeraw, Fikite Girma
Institute for Human Development, East Africa
Background: Most children with developmental disabilities (DD) live in low- and middle-income countries, but access to services is limited, impacting their ability to thrive. Pilot study findings of the World Health Organization’s Caregiver Skills Training (WHO CST) intervention, which equips caregivers with strategies to facilitate learning and adaptive behaviours in children with DD, are promising but evidence from an appropriately powered trial delivered by non-specialist facilitators is lacking. This study will investigate the effectiveness and the resource impacts and costs and consequences of the WHO CST intervention in four sites in rural and urban Kenya and Ethiopia.
Methods: …
La Salud Es Importante: Libro De Actividades (80-Pages), Your Very Favorite, Children's Health, Lorraine Sheldon, May Bressler
La Salud Es Importante: Libro De Actividades (80-Pages), Your Very Favorite, Children's Health, Lorraine Sheldon, May Bressler
Spanish
Health Matters! is a Spanish-language health literacy resource designed for pediatric patients and their families. Written at an approximately 6th-grade reading level, it supports patient education through engaging coloring and activity pages.
The content covers a wide range of health and wellness topics, including body systems, nutrition, mental wellness, patient safety, and social-emotional skills such as building friendships and navigating conversations when returning to school. Developed for use in both hospital settings and the broader community, the resource promotes learning through interactive, age-appropriate activities.
This printable PDF version contains the complete collection of activities and comprises 80 pages. The resource …
Corrigendum: Sars-Cov-2 Seroprevalence In Pregnant Women In Kilifi, Kenya From March 2020 To March 2022, Angela Koech, Geoffrey Omuse, Joseph Mutunga, Moses Mukhanya, Onesmus Wanje, Grace Mwashigadi, Geoffrey Katana, Rachel Craik, Alex Mugo, Marleen Temmerman
Corrigendum: Sars-Cov-2 Seroprevalence In Pregnant Women In Kilifi, Kenya From March 2020 To March 2022, Angela Koech, Geoffrey Omuse, Joseph Mutunga, Moses Mukhanya, Onesmus Wanje, Grace Mwashigadi, Geoffrey Katana, Rachel Craik, Alex Mugo, Marleen Temmerman
Pathology, East Africa
Background: Seroprevalence studies are an alternative approach to estimating the extent of transmission of SARS-CoV-2 and the evolution of the pandemic in different geographical settings. We aimed to determine the SARS-CoV-2 seroprevalence from March 2020 to March 2022 in a rural and urban setting in Kilifi County, Kenya.
Methods: We obtained representative random samples of stored serum from a pregnancy cohort study for the period March 2020 to March 2022 and tested for antibodies against the spike protein using a qualitative SARS-CoV-2 ELISA kit (Wantai, total antibodies). All positive samples were retested for anti-SARS-CoV-2 anti-nucleocapsid antibodies (Euroimmun, ELISA kits, NCP, …
Pulmonary Vascular Manifestations Of Hereditary Haemorrhagic Telangiectasia, Sarah Cullivan, Barry Kevane, Brian Mccullagh, Terry M O'Connor, Robin Condliffe, Sean Gaine
Pulmonary Vascular Manifestations Of Hereditary Haemorrhagic Telangiectasia, Sarah Cullivan, Barry Kevane, Brian Mccullagh, Terry M O'Connor, Robin Condliffe, Sean Gaine
Children’s Nutrition Research Center Staff Publications
Hereditary haemorrhagic telangiectasia (HHT) is an autosomal dominant, multisystem disorder that manifests with a spectrum of disease including cardiopulmonary complications. HHT is characterised by aberrant signalling via the transforming growth factor β (TGFβ) pathway, with loss of vascular integrity, angiogenesis and vascular dysplasia. The disease has an estimated prevalence of 1 in 5000 persons and the penetrance increases with increasing age. HHT commonly presents with epistaxis and telangiectasia, while visceral arteriovenous malformations are not uncommon. Mutations in the ENG, ACVRL1 and MADH4 genes account for 97% of all HHT cases, and it is recommended that genetic tests are used in …
Benefits Of Calorie Restriction In Mice Are Mediated Via Energy Imbalance, Not Absolute Energy Or Protein Intake, Daniel L Smith, Sharon E Mitchell, Maria S Johnson, Victoria K Gibbs, Stephanie Dickinson, Beate Henschel, Rui Li, Kathryn A Kaiser, Daniella E Chusyd, Andrew W Brown, David B Allison, John R Speakman, Tim R Nagy
Benefits Of Calorie Restriction In Mice Are Mediated Via Energy Imbalance, Not Absolute Energy Or Protein Intake, Daniel L Smith, Sharon E Mitchell, Maria S Johnson, Victoria K Gibbs, Stephanie Dickinson, Beate Henschel, Rui Li, Kathryn A Kaiser, Daniella E Chusyd, Andrew W Brown, David B Allison, John R Speakman, Tim R Nagy
Children’s Nutrition Research Center Staff Publications
Caloric restriction (CR) results in reduced energy and protein intake, raising questions about protein restriction's contribution to CR longevity benefits. We kept ad libitum (AL)-fed male C57BL/6J mice at 27°C (AL27) and pair-fed (PF) mice at 22°C (22(PF27)). The 22(PF27) group was fed to match AL27 while restricted for calories due to cold-induced metabolism. The 22(PF27) mice had significantly lower body weight, lean mass, fat mass, leptin, IGF-1, and TNF-α levels than AL27 mice (p< 0.001 for all). Manipulations over ~11 weeks resulted in significant differences in body temperature, physical activity, and expression of key genes linked to hunger in the hypothalamus. Survival was significantly greater in 22(PF27) compared to AL27 overall (p< 0.001). CR in the context of equivalent energy and protein intake resulted in hormonal, metabolic, and physiological benefits and extended longevity. Hence, energy imbalance, rather than low energy or protein intake per se, mediates the benefits of CR.
Metagenomic Study Of The Mesa: Detection Of Gemella Morbillorum And Association With Coronary Heart Disease, Kent D Taylor, Alexis C Wood, Jerome I Rotter, Xiuqing Guo, David M Herrington, W Craig Johnson, Wendy S Post, Russell P Tracy, Stephen S Rich, Shaista Malik
Metagenomic Study Of The Mesa: Detection Of Gemella Morbillorum And Association With Coronary Heart Disease, Kent D Taylor, Alexis C Wood, Jerome I Rotter, Xiuqing Guo, David M Herrington, W Craig Johnson, Wendy S Post, Russell P Tracy, Stephen S Rich, Shaista Malik
Faculty, Staff and Students Publications
BACKGROUND: Inflammation is a feature of coronary heart disease (CHD), but the role of proinflammatory microbial infection in CHD remains understudied.
METHODS AND RESULTS: CHD was defined in the MESA (Multi-Ethnic Study of Atherosclerosis) as myocardial infarction (251 participants), resuscitated arrest (2 participants), and CHD death (80 participants). We analyzed sequencing reads from 4421 MESA participants in the National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine program using the PathSeq workflow of the Genome Analysis Tool Kit and a 65-gigabase microbial reference. Paired reads aligning to 840 microbes were detected in >1% of participants. The association of the …
Blend Feeding Broilers To Daily Nutrient Requirements, J.T. Pope
Blend Feeding Broilers To Daily Nutrient Requirements, J.T. Pope
Proceedings of the Arkansas Nutrition Conference
Broiler producers and nutritionists have used phase feeding as a practical means to define broiler feeding programs. Each feed phase has discreet nutrient definitions intended to be fed for a defined number of days based on a feed mass delivered per broiler. A typical broiler feeding program would consist of three to five feed phases over the production cycle that intend to address the changing nutrient requirements as broilers age. Phase feeding programs are easily defined, practical to manage, and provide a predictable cost structure for broiler producers. Despite the practicality of phase feeding, there are inherent flaws that will …
Current Trends And Experiences From A Contract Research Organization Perspective, Dan Moore
Current Trends And Experiences From A Contract Research Organization Perspective, Dan Moore
Proceedings of the Arkansas Nutrition Conference
The primary goal of this presentation is to provide an update on the trends of research observed at a contract research organization (CRO) in recent years as it relates to species, study design type and products tested, as well as, challenge models used and products that have shown benefits in various study designs. The information in the presentation is based off of studies conducted from 2014-2024 at one CRO, Colorado Quality Research (CQR), and represents the experiences at CQR. Many of the parameters discussed will be from 2014-2019 and 2020-2024 to observe trends from over 5 years ago and more …
Importance Of A Rooster Feed In Broiler Breeder Production, Alex Corzo, Marcelo Silva
Importance Of A Rooster Feed In Broiler Breeder Production, Alex Corzo, Marcelo Silva
Proceedings of the Arkansas Nutrition Conference
Of all feed phases in poultry production, rooster feeding is arguably the least studied. During the rear phase, there is general agreement that male and female broiler breeders can be provided a common feed program, only differing on feed amounts provided, that results in growth targets reached for each sex. It is during the production phase that there is some disagreement on the best way to support the nutritional needs of the adult rooster. A considerable segment of the world does employ a rooster feed as a way to better support the nutritional needs of working males. Other poultry operations …