Digital Commons Network^™

Ketamine’S Mechanism Of Action With An Emphasis On Neuroimmune Regulation: Can The Complement System Complement Ketamine’S Antidepressant Effects?, Brandi Quintanilla, Carlos A Zarate, Anilkumar Pillai

Faculty, Staff and Student Publications

Over 300 million people worldwide suffer from major depressive disorder (MDD). Unfortunately, only 30-40% of patients with MDD achieve complete remission after conventional monoamine antidepressant therapy. In recent years, ketamine has revolutionized the treatment of MDD, with its rapid antidepressant effects manifesting within a few hours as opposed to weeks with conventional antidepressants. Many research endeavors have sought to identify ketamine's mechanism of action in mood disorders; while many studies have focused on ketamine's role in glutamatergic modulation, several studies have implicated its role in regulating neuroinflammation. The complement system is an important component of the innate immune response vital …

Resting-State Eeg Microstate Features For Major Depressive Disorder Classification, George M. V. Quinn

Dissertations, Theses, and Capstone Projects

Neuroimaging studies have revealed consistent abnormalities in functional connectivity within specific neural networks that may serve as biomarkers for major depressive disorder (MDD). It is important to find inexpensive, non-invasive techniques that target these biomarkers to make diagnosis easier and more objective. EEG microstates are quasi-stable potential topographies that are thought to reflect the quasi-stable network activity of the underlying neural generators. MDD has been shown to alter features of the four canonical EEG microstates (A, B, C, D) with some conflicting results. The most consistent network abnormalities in MDD are found in the anterior default mode network, and this …

Examining Mental Health Differences Between Traditional And Nontraditional College Students From 2017-2022, Terrence A. Calistro Jr.

Dissertations, Theses, and Capstone Projects

The COVID-19 pandemic and societal changes in response to the pandemic have contributed to increasing the prevalence of mental health issues among college students globally. Because of their additional responsibilities, the prevalence of mental issues among the subpopulation of Nontraditional College Students (NTCS) is even more concerning. NTCS possess at least one of the following characteristics (e.g., working full-time, part-time employment, having financial dependents, etc.) that differentiates them from typical college students who enter higher education right after high school. Prior research has shown that NTCS generally experience more life stressors and challenges associated with mental health issues (e.g., depression, …

A Potential Role For Magi-1 In The Bi-Directional Relationship Between Major Depressive Disorder And Cardiovascular Disease, Priyanka Banerjee, Khanh Chau, Sivareddy Kotla, Eleanor L Davis, Estefani Berrios Turcios, Shengyu Li, Zhang Pengzhi, Guangyu Wang, Gopi Krishna Kolluru, Abhishek Jain, John P Cooke, Junichi Abe, Nhat-Tu Le

Faculty, Staff and Student Publications

Purpose of review: Major Depressive Disorder (MDD) is characterized by persistent symptoms such as fatigue, loss of interest in activities, feelings of sadness and worthlessness. MDD often coexist with cardiovascular disease (CVD), yet the precise link between these conditions remains unclear. This review explores factors underlying the development of MDD and CVD, including genetic, epigenetic, platelet activation, inflammation, hypothalamic-pituitary-adrenal (HPA) axis activation, endothelial cell (EC) dysfunction, and blood-brain barrier (BBB) disruption.

Recent findings: Single nucleotide polymorphisms (SNPs) in the membrane-associated guanylate kinase WW and PDZ domain-containing protein 1 (MAGI-1) are associated with neuroticism and psychiatric disorders including MDD. SNPs in …

Developing An Ordered Logistics Regression Model For Denture Hygiene Among Elderly In Residential Care Homes, Wan Muhamad Amir W Ahmad, Ruhana Hasan, Mohamad Nasarudin Adnan, Farah Muna Mohamad Ghazali, Hazik Bin Shahzad, Nor Azlida Aleng, Mohamad Shafiq Mohd Ibrahim

Journal of Dentistry Indonesia

With a global aging population, the oral hygiene of elderly individuals in institutional settings requires unique management. Maintaining adequate denture hygiene is a critical aspect of their overall well-being, while neglecting denture hygiene can lead to various oral health issues, malnutrition, and further impacting their overall health. Objective: This paper aims to provide a preliminary overview of denture hygiene care among the elderly using an ordered logistics model. Methods: Data was obtained from 174 participants in two government institutional homes in Malaysia. The Principle Components Analysis (PCA) was used to identify significant variables and an ordered logistic model …

Postpartum Depression Screening In The Neonatal Intensive Care Unit At A Tertiary Pediatric Hospital, Abbie Bates

Doctor of Nursing Practice Final Manuscripts

POSTPARTUM DEPRESSION SCREENING IN THE NEONATAL INTENSIVE CARE UNIT AT A TERTIARY PEDICTRIC HOSPITAL

By

Abbie Kim Bates

Razel Bacuetes Milo, PH.D. DNP., FNP-C

Background: Postpartum depression (PPD) is a treatable mood disorder with an onset at 1-3 months after childbirth. In the United States, PPD occurs at a rate of 1 in 8 women and as high as 1 in 5 women in parts of the country. In unique populations such as the neonatal intensive care unit (NICU), PPD rates can be as high as 40%. The treatment rate for PPD is 50% with a sizable percentage of …

The Neuroscience Of Mindfulness Based Art Therapy: A Literature Review, Elizabeth Strasser

Expressive Therapies Capstone Theses

Art therapy and neuroscience are two fields which are currently growing and expanding with the development of new technology which allows for therapists and scientists to advance their understanding of how the brain and the body respond to the world around us. The interaction between the brain, body, and environment is complex, and for the sake of clarity for this thesis this interaction will be conceptualized through the lens of the body-mind model, polyvagal theory, neuroaesthetics, the flow state, mindfulness, sensory engagement, and art as therapy. Neuroscience in relation to psychology can be used to develop a deeper understanding of …

School Counselor Capacity Building: A Literature Review, Yulizar Yulizar, Ahman Ahman, Juntika Nurihsan, Ipah Saripah

Jurnal Kajian Bimbingan dan Konseling

Capacity describes the human ability to perform, maintain itself, and self-renew. The concept of capacity building is concerned with three distinct levels: the individual, the organizational, and the community level. The literature on capacity building for school counselors is quite diverse. Accordingly, a comprehensive review of the emerging literature is required. This study conducted a systematic literature review exploring the current state of knowledge regarding the capacity building of school counselors. This study was conducted in accordance with the Standard Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P), which guided the selection of 30 articles that met the …

Rasch Validation Of Arabic Scale Of Mental Health (Asmh) In Indonesian Version To Measure Adolescent Mental Health, Dody Hartanto, Mufied Fauziah, Yenni Rizal, Imam Azhari, Ratu Matahari, Parhan Fauzan, Nuri Cholidah Hanum, Diki Herdiansyah

Jurnal Kajian Bimbingan dan Konseling

Mental health is a crucial aspect for adolescents, as those with poor mental health may experience conditions ranging from depression and anxiety disorders to suicidal tendencies. Identifying mental health issues is essential, necessitating an instrument to assess adolescent mental health. This study aims to adapt the Arabic Scale of Mental Health (ASMH) into Indonesian and evaluate its validity using the Rasch model. The adaptation process followed the Procedures and Guidelines for Translating Counselling Assessment as outlined by Lenz, Gómez Soler, Dell'Aquilla, and Uribe. The translated instrument was administered to 685 high school and vocational school students from Yogyakarta. The instrument …

Relationship Between Academic Burnout And Academic Resilience Manifest In Prospective Counselors During The New Normal Era, Indriyana Rachmawati, Moh Farozin, Agus Basuki

Jurnal Kajian Bimbingan dan Konseling

Academic resilience has become an interesting topic of discussion as a result of the increase in academic burnout experienced by prospective counselors recently as a result of increasing academic assignments. Prospective counselors who experience academic burnout generally have poor academic resilience because they feel tired or bored with academic tasks while still studying, and this has an impact on the resulting performance. This research aims to determine the relationship between academic burnout and the academic resilience of prospective counselors. We used a quantitative research method, employing a correlation research design, to reveal the relationship between the two. The research sample …

Group Counseling With Motivational Interviewing Approach To Enhance Intrinsic Motivation And Academic Engagement, Arie Ichwan Nurhidayat, Mulawarman Mulawarman, Sunawan Sunawan

Jurnal Kajian Bimbingan dan Konseling

The objective of this study was to assess the efficacy of motivational interviewing (MI) group counseling in enhancing intrinsic motivation and academic engagement among students at State Senior High School 2 Sragen, Indonesia. Students with low intrinsic motivation and academic engagement often display a lack of attention during learning activities, disinterest in school, use of cell phones for non-academic purposes during study time, and failure to complete assigned tasks. This study employed a pretest and multiple posttest design, with 14 students selected via purposive sampling and subsequently divided into two groups: the experimental group (7 students), who received group counseling …

Boosting Teacher Work Engagement: The Role Of Self-Efficacy, Resilience, And Personality Traits, Ajar Dirgantoro, Nur Eva, Fattah Hanurrawan, Imanuel Hitipeuw

Jurnal Kajian Bimbingan dan Konseling

The role of a teacher in the world of education greatly affects how the quality of students with the expected changes cannot be separated from the responsibility of a teacher in educating, guiding, motivating and being a facilitator for these students. However, low work involvement by teachers is not able to achieve organizational or school success in producing quality successors. The intended work engagement is a series of results from the teacher's self-efficacy and resilience towards himself and work tasks. This study aims to empirically examine the effect of self-efficacy and resilience on teacher work engagement with personality traits as …

Work Readiness Of Final Year Students Observed From Grit And Career Adaptability, Vivianora Diva, Pratista Arya Satwika

Jurnal Kajian Bimbingan dan Konseling

Universities are obliged to prepare graduates of the highest caliber and ensure that their qualifications align with the requirements of the professional world. Therefore, it is essential for them to equip students with the necessary skills and knowledge before they enter the workforce. Nevertheless, a considerable number of students remain inadequately prepared for the demands of the workplace. The capacity to persevere and adapt to new circumstances are two key attributes that can influence an individual's preparedness for professional roles. This study aims to ascertain the relationship between grit and career adaptability with the work readiness of final-year students. This …

Psychological Dynamics Among Adolescents With Self-Harm Behavior Based On Rational Emotive Behavior Therapy, Hengki Tri Hidayatullah, Arbin Janu Setiyowati, Irene Maya Simon, Riyani Indriyati, Maria Teresa Mattingly

Jurnal Kajian Bimbingan dan Konseling

The objective of this study was to ascertain the psychological underpinnings of self-harm behaviors among adolescents, with a particular emphasis on the tenets of rational emotive behavior therapy (REBT). Additionally, this study aimed to elucidate the various forms of self-harm behaviors and the underlying factors that contribute to these behaviors in adolescents. This research employed a qualitative approach with a phenomenological research design. The research subjects were students at State Senior High School 1 Batu, Indonesia, selected based on certain criteria in accordance with the research needs (purposive sampling). The results demonstrate three key aspects of the psychological dynamics of …

Development Of Metaverse-Based Virtual Reality Counseling: Technology-Assisted Psychological Services For Students With Disabilities, Imam Ariffudin, Muhammad Nur Hudha, Akhmad Zaini, Ajeng Intan Nur Rahmawati

Jurnal Kajian Bimbingan dan Konseling

This study aims to develop a metaverse-based Virtual Reality Counseling (VRC) medium to support psychological services for students with special needs. The research method used is the research and development method with the ADDIE model (Analysis, Design, Development, Implementation, and Evaluation). The results show that the metaverse-based VRC medium has met the media acceptability aspects, making it feasible for effective implementation. Additionally, experimental results indicate a decrease in the levels of mental health disorders experienced by the counselees after undergoing individual counseling assisted by the metaverse-based VRC medium. The impact of this study suggests that the metaverse-based VRC medium is …

Perceptions Of Substance Use And Sexual Risk Behaviors Among Adolescent Women Involved In Juvenile Justice, Catherine E. Dunlop, Aynsley H. M Scheffert, Allison Cowling, Maya Kohavi, Laura J. Benjamins, Danielle Parish

Department of Pediatrics

CHOICES-TEEN is a bundled intervention aimed at reducing the risks of unintended pregnancy, sexually transmitted infections, and alcohol- and tobacco-exposed pregnancies for adolescent girls involved in the juvenile justice system. We examined youths’ (N = 22) elicited pros and cons concerning alcohol, tobacco, condom, and contraception use to inform future iterations of CHOICES-TEEN and other prevention programming during a one-arm pilot study. Content analysis was used to identify recurring themes elicited and recorded during a decisional balance exercise with a counselor. The most recurrent pros and cons were factors that directly affected these adolescents, with more immediate consequences. The …

A Phenomenological Examination Of The Perception Of Psychopathological Misdiagnosis In Gifted Men, Tina Glass

Electronic Theses and Dissertations

While the exact prevalence of psychopathological misdiagnosis in gifted children is unknown, it is an occurrence within the gifted population (Amend & Beljan, 2009; Batstra et al., 2012; Bishop & Rinn, 2019; Bishop & Rinn, 2020; Coon, 2014; Webb et al., 2016). However, there is a gap in the literature related to psychopathological misdiagnosis specific to gifted males. (Desmet & Pereira, 2021; Ecklund et al., 2014; Eren et al., 2018; Neu & Weinfeld, 2007; OECD, 2015; Preckel et al., 2015; Watts, 2022). This transcendental phenomenological study leveraged Bronfenbrenner’s Bioecological Model for Human Development (Bronfenbrenner & Morris, 2006) as a theoretical …

Baby Dust: A Narrative Analysis Of Infertility Journeys On Youtube, Patricia Carrillo

Electronic Theses and Dissertations

Infertility is a distressing experience for those diagnosed and often exacerbated by engagement with biomedical treatments. This thesis is an exploration of infertility “journeys” posted on YouTube. Through a narrative analysis of 8 YouTube channels, several key themes were identified, specifically embodiment of the infertility label, barriers to treatment, and agency. This work uses the mindful body framework to look at how the individual body, social body, and body politic shape and reinforce these themes in the context of biomedical infertility treatment. These findings suggest infertility is a dynamic and distressing experience but by engaging in the narrative process, through …

Naturalistic Evaluation Of Embedded Social-Emotional Services In Early Childcare And Education Settings: Teacher Outcomes, Andrew B. Mcgee

Electronic Theses and Dissertations

In two studies, this dissertation evaluated relations among early childhood education (ECE) teachers’ well-being and embedded social-emotional services. Study 1 focused on occupational stress, burnout, and mental health, exploring the relations among stress and mental health, and the associations with social-emotional services. Study 1 also explored group differences in stress, burnout, mental health, and social-emotional services for teachers who identified as Latinx. Results showed that occupational stress and social emotional services had significant main effects on mental health (burnout, depression, anxiety), with associations varying across mental health measures. Occupational stress was associated with adverse mental health outcomes, while social-emotional support …

The Intersection Of Consensual Non-Monogamy, Black Identity, And Power Dynamics: A Review And Proposal For Therapeutic Models, Casey Nelson

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Consensual non-monogamy (CNM) and polyamory are types of relationship structures that differ in many ways from monogamy. CNM is becoming more prevalent (Moors, 2023; Scoats & Campbell, 2022). In the United States and Canada, 1 in 5 people have engaged in some form of CNM (Moors, 2023). As more individuals engage in CNM relationships and potentially seek out couples therapy, therapists will be tasked with assisting individuals navigating relationship distress occurring within these unique relationship structures. There is limited research, or empirically validated, treatment models for working with couples with intersecting identities. To date, there has yet to be an …

A Needs-Assessment Survey Of The High School Lgbtq+ Environment By A Health Science Center Interprofessional Team, Rafael Velasquez, Mary E. Moore, Gabrielle Sheets, Christian Nieves-Rivera, Sonya Van Nuland, Martha Cuccia, Fern Tsien, Andrew D. Hollenbach

School of Medicine Faculty Publications

Despite improvements in the awareness and acceptance of lesbian, gay, bisexual, transgender, queer, and other sexual and gender diverse (LGBTQ+) individuals, the LGBTQ+ community continues to experience discrimination, which can result in adverse health outcomes. In particular, LGBTQ+ youth have an increased risk of experiencing depression, substance abuse, and suicide. Societal stigma and rejection, bullying, and familial disapproval all contribute to these health disparities. In recognition of these inequities, an interprofessional team of biomedical faculty members, staff, and trainees from the Louisiana State University Health Science Center (LSUHSC) in New Orleans developed the needs-assessment evaluation, the Gender and Sexual Minority …

The Role Of Gdf5 In Regulating Enthesopathy Development In The Hyp Mouse Model Of Xlh, Melissa Sorsby, Shaza Almardini, Ahmad Alayyat, Ashleigh Hughes, Shreya Venkat, Mansoor Rahman, Jiana Baker, Rakshya Rana, Vicki Rosen, Eva S Liu

Staff and Researcher Publications

X-linked hypophosphatemia (XLH) is caused by mutations in PHEX, leading to rickets and osteomalacia. Adults affected with XLH develop a mineralization of the bone-tendon attachment site (enthesis), called enthesopathy, which causes significant pain and impaired movement. Entheses in mice with XLH (Hyp) have enhanced bone morphogenetic protein (BMP) and Indian hedgehog (IHH) signaling. Treatment of Hyp mice with the BMP signaling blocker palovarotene attenuated BMP/IHH signaling in Hyp entheses, thus indicating that BMP signaling plays a pathogenic role in enthesopathy development and that IHH signaling is activated by BMP signaling in entheses. It was previously shown that mRNA expression of …

Team-Centered Care After Trauma Patient Death: Promoting Healers’ Healing By Humanizing Our Roles, Sydni Au Hoy, Carlie J. Arbaugh, Caitlin P. Bungo, Amanda J. Deutsch, Bonnie E. Chow, Kristen Gallegos, Nerissa Alansalon, Emmanuel Jisrawi, Al’Ai Alvarez, Brooke Gurland, Joseph Forrester

Journal of Wellness

Introduction: Recurrent exposures to adverse patient events, including death, affect all members of the care team and can have long-term effects on clinician performance, personal well-being, and patient safety. Recognizing the impact of patient deaths on care teams is essential to mitigating potential risks of increased clinician burnout. We share the outcomes of a three-month pilot wellness intervention implemented at a busy academic hospital, directed explicitly toward resuscitation care teams managing patients who die from traumatic injuries.

Approach: A collaborative group from Stanford’s Trauma Surgery, Emergency Department (ED), and well-being leadership developed an integrated workflow to connect with …

Adverse Childhood Experiences And Effects On Delinquency, Katherine Lank

Master of Arts in Human Services

Youth involved in delinquent acts are seen interacting with the juvenile justice system at an alarming rate. Adverse childhood experiences influence the development of behavior and chances of taking risks. Children who grow up in a household with an unfit parent, substance abuse, or mental health disorders are seen turning to delinquent acts for gratification. This can have a higher chance of poor educational performance, unemployment, increased law enforcement interactions, and long-term mental and physical disabilities. Searching literature consisted of finding external factors and their control on brain development and future adult behaviors. Research was conducted on the school-to-prison pipeline, …

Discovery And Generalization Of Tissue Structures From Spatial Omics Data, Zhenqin Wu, Ayano Kondo, Monee Mcgrady, Ethan A G Baker, Benjamin Chidester, Eric Wu, Maha K Rahim, Nathan A Bracey, Vivek Charu, Raymond J Cho, Jeffrey B Cheng, Maryam Afkarian, James Zou, Aaron T Mayer, Alexandro E Trevino

Staff and Researcher Publications

Tissues are organized into anatomical and functional units at different scales. New technologies for high-dimensional molecular profiling in situ have enabled the characterization of structure-function relationships in increasing molecular detail. However, it remains a challenge to consistently identify key functional units across experiments, tissues, and disease contexts, a task that demands extensive manual annotation. Here, we present spatial cellular graph partitioning (SCGP), a flexible method for the unsupervised annotation of tissue structures. We further present a reference-query extension pipeline, SCGP-Extension, that generalizes reference tissue structure labels to previously unseen samples, performing data integration and tissue structure discovery. Our experiments demonstrate …

Companion Dogs And Depression, Anxiety, And Posttraumatic Stress Disorder In Adult Icu Survivors: A Scoping Review, Lindsey Nelson, Sue Lasiter, Amanda Emerson

People and Animals: The International Journal of Research and Practice

Intensive care unit (ICU) survivors are at risk for developing persistent psychological sequelae that have been linked to decreased quality of life and increased mortality after hospital discharge. Standardized evidence-based treatments are lacking, mainly focus on physical rather than psychological recovery, and often occur in formal settings. Benefits of human– companion dog relationships have not been explored in the ICU survivor population before. Thus, the purposes of our review were to summarize the literature focused on the influence of companion dogs on depression, anxiety, and posttraumatic stress disorder (PTSD); identify what is known about the potential role companion dogs play …

Racial Identity Development And Imposter Phenomenon As Predictors Of Counselor Self-Efficacy, Erica D. Wade-Ball, Dana T. Isawi, Teresa A. Fisher

Journal of Counselor Preparation and Supervision

The authors utilized a correlational research design to examine the role of racial identity development and impostor phenomenon in predicting counselor self-efficacy among counselors-in-training of color. Racial identity development significantly predicts counselor self-efficacy, and imposter phenomenon is correlated with counselor self-efficacy. Based on the findings, the authors provide implications and recommendations for counselor educators and supervisors.

Using Fink’S Taxonomy In Counseling Practicum And Internship Courses, Kailey Bradley, Emily Horton Phd

Journal of Counselor Preparation and Supervision

Fink’s Learning Taxonomy expanded upon Bloom’s Learning Taxonomy to provide concrete suggestions on development of significant learning experiences. Limited research exists on implementation of Fink’s learning Taxonomy in counselor education curriculum. As such, this conceptual article illuminates how the integration of Fink’s Learning Taxonomy could be used by educators to develop significant learning experiences within counseling internship and practicum courses.

Manualized Occupational Therapy Intervention For Children And Adolescents With Post-Traumatic Stress Disorder, Adam Mcmahon

Student Capstone Papers

Post-traumatic stress disorder (PTSD) in children can cause physiological and psychological reactions that can lead to impaired executive functioning and self-regulation skills that interfere with occupational engagement. Occupational Therapy (OT) utilizes an occupational perspective to treat children with PTSD. However, there is an absence of a manualized OT intervention in the literature that incorporates an occupation-based approach, utilizes graded occupation as the primary intervention, and tracks treatment progress and outcomes. The purpose of this capstone project was to create a manualized OT intervention protocol for OT practitioners to treat children with PTSD guided by the model of human occupation and …

Manualized Occupational Therapy Intervention For Children And Adolescents With Post-Traumatic Stress Disorder, Adam J. Mcmahon, Steven M. Gerardi

Summer 2024 OTD Capstone Symposium

The capstone poster demonstrates the purpose for a manualized occupational therapy (OT) intervention for OT practitioners to treat children with post-traumatic stress disorder. The intervention uses an occupation-based approach informed by behavioral activation therapy and the model of human occupation principles. The manual includes two parts. Part one demonstrates the foundational principles for OT practitioners to obtain knowledge, skills, and tools before implementing the intervention. Part two outlines the treatment process beginning with evaluation, introducing manualized OT intervention to the child and the family member(s) and/or caregiver(s), treatment application, progress note, and discharge. The manualized OT intervention will allow OT …