Digital Commons Network^™

Associations Between Reported Use Of Nutritional Labels And Calorie Intake In Us Adults: Findings From Nhanes 2017–2020, Ariana M. Chao, Nancy Greene, Alexandra Paul, Paule V. Joseph

College of Nursing Faculty Papers & Presentations

Objective: Caloric information is commonly displayed on nutritional fact labels and food menus. Yet evidence is limited on whether label use is associated with a reduced-calorie diet. This study examined the associations between the use of caloric information on nutritional facts and menu labels and daily caloric intake. Methods: We used data from adults in the National Health and Nutrition Examination Survey (NHANES) 2017–2020 to conduct a cross-sectional study. Calorie label use on nutritional labels and menus was assessed using the Flexible Consumer Behavior Survey telephone interview. Caloric intake was evaluated using the mean of two 24-h diet recalls implemented …

Unpacking Low Glycaemic Index (Gi) Food Purchase Intentions In An S-O-R Framework: The Multidimensional Moderating Roles Of Consumer Knowledge And Trust, Cao Henglei

Student Works (2020-2029)

Research aim: Examine Malaysian consumers’ decisions to purchase low-GI foods using the S–O–R framework, while considering how knowledge and trust shape these decisions. Design/Methodology/Approach: A quantitative survey was conducted among 302 Malaysian consumers, with data analysed via confirmatory factor analysis, structural equation modelling, and moderation analysis. Research findings: Attitudes toward low-GI foods are shaped by health consciousness, environmental concern, and social influence, but not price perception. Purchase intention is directly influenced by trust, with moderation observed only for subjective knowledge. Theoretical contribution/Originality: Extends the S–O–R framework through differentiating knowledge type and clarifying the role of trust in low-GI food consumption. …

Assessment Of Early Breast Cancer Response To Chemotherapy With Ultrasound Radiomics, Swapnil Dolui, Basak Dogan, Corinne Wessner, Jessica Porembka, Priscilla Machado, Bersu Ozcan, Nisha Unni, Maysa Abu-Khalaf, Flemming Forsberg, Kibo Nam, Kenneth Hoyt

Department of Medical Oncology Faculty Papers

Objective: This prospective study investigated the use of H-scan ultrasound (US) imaging as a novel component of a multiparametric radiomic analysis framework for characterizing human breast cancer response to neoadjuvant chemotherapy (NAC) before and early after treatment initiation. Methods: Thirty breast cancer patients scheduled for NAC were scanned using a clinical US system (Logiq E9, GE HealthCare) equipped with a 9L-D linear array transducer. Radiofrequency (RF) data was obtained at baseline (pre-NAC) and after 10% and 30% of the complete dose of chemotherapy. The RF data was analyzed by a bank of 256 frequency-shifted bandpass filters to form H-scan US …

Intouch Week Of March 23, 2026, New York Medical College

InTouch

• Match Day Marks a New Season of Growth for the Class of 2026
• NYMC Explores the Lasting Impact of Marie Curie at Women’s History Month Event
• Department of Public Health Introduces New Certificate Option
• NYMC Teams Shine at Inaugural RISE Case Competition
• New Vein-Harvesting Technique Could Reduce Bypass Graft Failure
• Spring Into Publishing: Meet the Experts
• Student Spotlight: Exploring Connections Between Alzheimer's Disease and Glaucoma

A Mitochondrial Plasma Proteomic Signature Identifies Metastatic Chromophobe Renal Cell Carcinoma, Clara Steiner, Tiegang Han, Steven Safi, Wafaa Bzeih, Hadi Mansour, Eddy Saad, Jessica F. Williams, Vinay K. Giri, Liliana Ascione, Yehonatan Elon, Adam P. Dicker, Yan Tang, Toni K. Choueiri, Elizabeth P. Henske, Wenxin Xu

Department of Radiation Oncology Faculty Papers

BACKGROUND: Chromophobe renal cell carcinoma (ChRCC) is characterized by the accumulation of abnormal mitochondria, a high rate of mitochondrial DNA (mtDNA) mutations, and altered oxidative metabolism. There are no existing circulating biomarkers to distinguish metastatic ChRCC from clear cell renal cell carcinoma (ccRCC).

METHODS: High-throughput plasma proteomic profiling using the SomaScan platform was performed in 18 ChRCC (including 16 metastatic ChRCC) and 197 metastatic ccRCC patients. Data were harmonized to generate a unified 7K-protein matrix.

RESULTS: Differential expression analysis was performed using limma (version 3.62.2). Of 7272 quantified human plasma proteins, 209 were differentially expressed between ChRCC and ccRCC. Upregulated …

A Retrospective Analysis Of Taxane-Based Chemotherapy In Small Bowel Adenocarcinoma, Mir Lim, Nikhil Grandhi, Preksha Shah, Kanwal Raghav, Victoria Serpas, Maria Pia Morelli, Katrina Pedersen, Aparna Kalyan, Mohamed Salem, Ryan Huey, John Paul Shen, Huamin Wang, Hua Wang, Anjali Vinocha, Jane Thomas, Robert Wolff, Michael J Overman

Faculty, Staff and Student Publications

Background: Small bowel adenocarcinoma (SBA) is molecularly distinct from colorectal and gastric cancers, yet treatment typically parallels colorectal cancer. We evaluated the activity of taxane-based therapy in the largest SBA cohort to date.

Methods: We retrospectively reviewed SBA patients treated with taxane-based chemotherapy at MD Anderson Cancer Center from 1994-2024. Eligible patients had pathologic confirmation, received >1 treatment cycle, and had tumor response evaluation. Survival analyses were analyzed using Kaplan-Meier and Cox proportional hazard models.

Results: Seventy patients were identified. Median age was 57, and 59% were male. Primary sites were duodenum (44%), jejunum (34%), and Ileum (16%). Metastatic sites …

Antimicrobial Activity Of Sulbactam-Durlobactam Against Acinetobacter Baumannii-Calcoaceticus Complex Strains Causing Non-Respiratory And Non-Bloodstream Infections From The United States (2023–2025), Elizabeth Cyr, Jill Argotsinger, Eric T Beck, Robin R Chamberland, Andrew E Clark, Anne R Daniels, Rachael Liesman, Mark Fisher, Philip Gialanella, Jonathan Hand, Amanda T Harrington, Romney M Humphries, Holly Huse, Robert Hamilton-Seth, Julia D Hankins, Wesley D Kufel, Scott W Riddell, Meera Mehta, Ryan Demkowicz, A Brian Mochon, Hossein Salimnia, Ayesha Khan, Virginia M Pierce, Raghava Potula, Tsigereda Tekle, Patricia J Simner, Robert J Tibbetts, Christine Vu, Lilian M Abbo, Octavio Martinez, Rebekah E Dumm, Manohar B Mutnal, Timothy C Jenkins, Violeta Chávez, Paulette Pinargote, Jennifer Bowling, Erik Munson, Daniel V Zurawski, David P Nicolau, Tomefa E Asempa, On Behalf Of The Acinetobacter Baumannii Complex National Biorepository (Acnbio) Study Group

Faculty, Staff and Student Publications

Acinetobacter baumannii most often causes pneumonia in critically ill patients. However, A. baumannii is also an important cause of a broader range of infections, including skin/wound and urinary tract infections. This study aims to evaluate the in vitro activity of sulbactam-durlobactam and comparator antibiotics, including meropenem and cefiderocol against A. baumannii-calcoaceticus complex isolates from non-respiratory and non-bloodstream sources. Samples included 285 A. baumannii-calcoaceticus complex isolates enriched for carbapenem resistance collected across 17 states in the United States (January 2023–May 2025). Antimicrobial susceptibility tests were conducted by manual broth microdilution and interpreted according to Clinical and Laboratory Standards Institute (CLSI) and …

4-Aminoquinolines Block Heme Iron Reactivity And Interfere With Artemisinin Action, Melissa Rosenthal, Daniel E Goldberg

2020-Current year OA Pubs

Artemisinin-based combination therapies (ACTs) remain the mainstay of treatment for

Precision Percutaneous Coronary Intervention, Travis M Wilson, Uzair Munaf, Nafhat Shaikh, Affan Rizwan, Riyan Siddiqui, Hafeez Ul Hassan Virk, Mahboob Alam, Umair Khalid, Muzamil Khawaja, Tanawat Attachaipanich, Larisa H Cavallari, Tania Ahuja, Michael G Nanna, Samin K Sharma, Lloyd W Klein, Gary S Mintz, Chayakrit Krittanawong

Faculty, Staff and Students Publications

Precision-based percutaneous coronary intervention (PCI) integrates contemporary strategies across the pre-, intra-, and post-procedural phases to improve outcomes and minimize complications. Emerging evidence underscores the value of these strategies in reducing adverse events and improving procedural efficiency. While artificial intelligence and pharmacogenomics hold long-term promise for enhancing personalization, their clinical utility in PCI remains in the early stages of development.

Whole-Genome Crispr Screening Identifies Genetic Modifiers Of Stem Cell-Derived Islet Transplantation, Marlie M Maestas, Kameron Bradley, Mira Shunkarova, Noyonika Mukherjee, Matthew Ishahak, James Lu, Jeffrey R Millman

2020-Current year OA Pubs

INTRODUCTION: Genetically engineering human pluripotent stem cell (hPSC)-derived islets is a promising strategy for improving transplantation for diabetes cell therapy; however, genetic perturbations that modulate transplantation outcomes have yet to be systematically explored.

METHODS: To identify potential targets, we performed an unbiased whole-genome CRISPR-activation screen in transplanted stem cell-derived islets (SC-islets). Specifically, we created a stem cell line with CRISPR-activation components (HUES8-VPR) and then transduced these stem cells with a lentiviral guide RNA library targeting the whole human genome. Following transduction, the stem cells were differentiated into SC-islets, which were subsequently transplanted into NOD.Cg-PrkdcscidIl2rgtm1Wjl/SzJ (NSG) immunodeficient mice. After transplantation, SC-islets …

Mastr-Seq Enables Multiplexed Analysis Of Short Tandem Repeats With Sequencing, Chuanbin Su, Han-Seul Ryu, Keerthivasan Raanin Chandradoss, Thomas Malachowski, Ravi Boya, Linda Zhou, Hoa Emma Nguyen, Esteban O Mazzoni, Kristen J Brennand, Jennifer E Phillips-Cremins

2020-Current year OA Pubs

More than 60 human disorders are caused by unstable expansion of short tandem repeat (STR) tracts. These can exhibit cell-type-specific mosaicism in several repeat expansion disorders and remain difficult to characterize due to technical challenges intrinsic to highly repetitive sequences. Long-read approaches can measure STR length and DNA methylation on the same single molecule but are low-throughput and cost-prohibitive across multiple experimental conditions or patient samples. Here, we present MASTR-seq, multiplexed analysis of short tandem repeats with sequencing, for cost-effective, high-throughput, accurate measurement of STR genotype and DNA methylation at single-allele resolution. MASTR-seq couples long-read sequencing, Cas9-mediated target enrichment, size …

Protocol For Spatial Profiling Of Immune Cells In The Mouse Cornea And Conjunctiva Using Nanostring Geomx Dsp And Ncounterpro Platforms, Lois Kim, Karthikeyan Ramasamy, Ajay Sharma

Pharmacy Faculty Articles and Research

Quantification of immune cells and their activation status in a spatially specific manner in a healthy or diseased tissue is a valuable tool in immunology. Here, we present a protocol for the spatial profiling of immune cells in the mouse cornea and conjunctiva. We describe steps for immunostaining with photocleavable oligonucleotide-conjugated antibodies, selecting regions of interest (ROIs), and collecting UV-cleaved oligonucleotides using GeoMx DSP. We then detail procedures for hybridizing collected oligonucleotides, cartridge blotting using nCounter Pro Prep, data acquisition, and data analysis.

Therapeutic Plasma Exchange For Uncontrollable Bleeding After Platelet Inhibition With Ticagrelor: A Report Of 2 Cases, Amanda Herrmann, Brenda Mai, Yu Bai, Brian Castillo, Biswajit Kar, Kimberly Klein, Ismael A Salas De Armas, Eric Salazar, Hlaing Tint, Igor D Gregoric

Faculty, Staff and Student Publications

Case series

Patients: Male, 52-year-old Male, 66-year-old

Final Diagnosis: Uncontrolled bleeding following ticagrelor associated with cardiac surgery

Symptoms: Bleeding

Clinical Procedure: —

Specialty: Cardiology Critical Care Medicine Pathology

Objective: Unusual clinical course

Background

Acute coronary syndrome is the most common cause of death in the United States. Successful intervention often requires a multi-therapeutic approach, including percutaneous coronary intervention (PCI) and antiplatelet agents such as ticagrelor. However, the use of antiplatelet agents can cause life-threatening bleeding, particularly during emergency procedures. Therapeutic plasma exchange (TPE) is a procedure that selectively removes the patient’s plasma to eliminate harmful substances. Here, we present 2 …

Influence Of Ceramic Thickness And Cad/Cam Ceramic Materials On The Fracture Resistance Of Indirect Restorations: An In Vitro Study, Lara El Hanach, Karim Corbani, Nabil Ghosn, Ryan Harouny, Cynthia Kassis

International Arab Journal of Dentistry

Objectives: This in-vitro study aimed to evaluate the impact of different CAD/CAM materials (IPS e.max® CAD and Cerasmart®) and thicknesses (0.7 mm, 1 mm, and 1.5 mm) on the fracture resistance of indirect overlay restorations.

Methods: Sixty-three human third molars were divided into 7 groups (n=9) based on material and thickness, including a control group of 9 sound teeth. Only 54 specimens were prepared using a thin-section cutting machine, scanned, and their scans were used to fabricate overlays from different materials and thicknesses. After adhesive cementation, the overlays underwent thermal cyclic loading (5,000 cycles between 5°C and 55°C). A universal …

Henri Nouwen: Theologian, Caregiver - How Do His Writings Support Informal Caregivers?, Dr. Julie Yonker

University Faculty Publications and Creative Works

•Analyze the Impact and Visibility of Informal Caregivers   •Evaluate Henri Nouwen’s Theological Framework for Caregiving   •Develop Practical Support Strategies for Faith Communities

Spiritual Scaffolding: Integrating Acute Care Nursing Empathy And Caregiver Religiosity To Enhance Well-Being For The Work Of The Informal Caregiver, Dr. Julie Yonker, Alyssa Pokharel

University Faculty Publications and Creative Works

Informal caregivers—adults providing unpaid medical or physical care to family or friends with adult-onset conditions— are essential yet often unrecognized contributors to U.S. health care. • One in four adults serve as caregivers, providing care valued at over $600 billion (AARP 2025). • Despite their vital role, many lack training, social support, and connection to professional care networks. • Health professionals can promote sustainable, whole-person care by integrating caregiver training and referral systems into acute care practice.

Pediatric Simulation And Emergency Nurse Confidence, Katherine E. Wright

Student Scholarly Projects

Practice Problem: Nurses working in a general emergency department (GED) with a low (3.3%) pediatric patient volume expressed a lack of confidence caring for complex pediatric patients.

PICOT: In general emergency department nurses (P), how does participating in a pediatric simulation event (I), compared to current practice (C), affect nurse confidence scores caring for pediatric patients (O) over 6 weeks (T)?

Evidence: A review of over 17 evidence-based resources found good quality evidence that suggested participating in a simulation event can improve nurse confidence.

Intervention: Over six weeks, GED staff members participated in a pediatric simulation event. The simulation utilized …

Hybrid Diabetes Coaching Model: Integrating In-Person And Telemedicine Strategies To Improve Glycemic Outcomes, Sandis A. Mundackal

Student Scholarly Projects

Practice Problem: In patients with type 2 diabetes, poor glycemic control among adults remains a significant challenge in primary care settings, particularly within federally qualified health centers (FQHCs) that serve underserved populations. At the FQHC practice site, patients were managed using standard care with quarterly follow- up visits, without a structured hybrid coaching approach. This inconsistency contributed to a high number of patients with hemoglobin A1c (HgbA1c) levels ≥ 9%, placing them at increased risk for diabetes-related complications.

PICOT Question: In adults with poorly controlled type 2 diabetes (HgbA1c ≥ 9%) (P), does monthly hybrid coaching delivered through in-person and/or …

Exploring The Intersection Of Faith, Empathy, And Healthcare Trust In The Experience Of Informal Caregivers, Dr. Julie Yonker, Elizabeth Yuniwo, Jamie Lee, Mesalenuo Tsurho, Meral Moawad, Toluwani Adekunle

University Faculty Publications and Creative Works

• Informal caregivers—adults providing unpaid medical or physical care to family or friends with adult-onset conditions—are essential yet often unrecognized contributors to U.S. health care. 
• One in four adults serve as caregivers, providing care valued at over $600 billion (AARP 2025). 
• Despite their vital role, many lack training, social support, and connection to professional care networks. 
• Public health professionals can promote sustainable, whole-person care by integrating caregiver training and referral systems into practice.

Aquifer Characteristics And Groundwater Flow Modeling For Sustainable Water Resources Development And Planning Using Modflow Software In India, Ravi Sharma

AUIQ Complementary Biological System

MODFLOW is one of the most commonly used numerical models for simulating groundwater flow. Its structured data design and compatibility with GIS tools make it suitable for groundwater assessment and planning. Groundwater forms an important part of the hydrological cycle and occurs within the pore spaces of sedimentary rocks or within fractures in hard rock terrains. Although its distribution beneath the surface is not always uniform or predictable, it is still considered one of the cleanest, most accessible, and quickly available freshwater sources. Numerical groundwater models help convert complex subsurface processes into simplified relationships that describe flow behavior. Even though …

Contribution Of G4 Structure To Alzheimer’S Disease And Tau Pathology, Lena Michaela Kallweit

Electronic Theses and Dissertations

The occurrence of Alzheimer’s Disease (AD) is rapidly increasing as our global population ages. With the majority of therapeutic drugs in the last couple of decades failing clinical trials, new molecular targets are needed to combat the expected influx of new AD cases. AD pathogenesis is associated with abnormal protein aggregation, characterized in part by intracellular accumulation of hyperphosphorylated tau (p-tau) in neurofibrillary tangles (NFTs). RNA has been identified as a major non-proteinaceous component of NFTs and has been implicated as an active cofactor in tau aggregation and spread. Recent work has shown that aggregates from AD brains contain almost …

Adaptations Of Collaborative/Therapeutic Assessment With Survivors Of Torture: Clinical Insights From Shareback Conversations, Samantha Correa

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Survivors of Torture (SoT) experience disproportionately high rates of PTSD, depression, and anxiety (Steel et al., 2009). Many SoT treatment programs use brief assessments to monitor symptoms (McFarlane & Kaplan, 2012). However, research on integrating feedback into treatment had been limited until Colpas et al.'s 2024 study on Sharebacks, a novel approach where clients review their progress with their clinician in structured feedback sessions. Given the therapeutic potential of assessment feedback (Tarocchi et al., 2013; Smith & George, 2012; Poston & Hanson, 2010) and Colpas et al.'s findings on Sharebacks' importance, this study explores how practitioners can most effectively incorporate …

Eligibility For Amyloid Targeting Therapies Among Primary Care Patients With Cognitive Symptoms, Beata Borgström Bolmsjö, Josef Barbosa Djärf, Danielle Van Westen, Suzanne E Schindler, Ayesha Fawad, Lyduine Collij, Ruben Smith, Niklas Mattsson-Carlgren, Erik Stomrud, Pontus Tideman, Oskar Hansson, Sebastian Palmqvist

2020-Current year OA Pubs

BACKGROUND: Alzheimer’s disease (AD) is the most common cause of dementia and a growing healthcare challenge. Amyloid-targeting therapies (ATT) may slow progression, but implementation is limited by logistical and economic barriers. As primary care is the first contact for most patients with cognitive concerns, quantifying treatment eligibility in this setting is essential. The purpose of this study was to estimate the proportion of primary care patients presenting with cognitive symptoms who are eligible for ATT. METHODS: This cohort study included patients presenting with cognitive symptoms in primary care across the region Skåne, in southern Sweden, recruited between January 2020 and …

Optimizing Clutch Performance In Euroleague Basketball: A Data-Driven Analysis Of Late-Game Decision-Making, Panagiotis F. Foteinakis, Stefania P. Pavlidou, Athanasios Chatzinikolaou, Nikolaos Stavropoulos, Maria Michalopoulou

Baltic Journal of Health and Physical Activity

Background: Decision-making during late-game possessions in basketball is considered one of the most essential aspects of winning a game. This study examined key determinants of late-game shot-making success in closely contested EuroLeague basketball matches, aiming to optimize offensive decision-making in clutch situations. Material and Methods: An observational analysis from the last two minutes of 83 EuroLeague games recorded 471 clutch shot attempts. Logistic regression and chi-square analyses assessed the impact of offense time, shot range, defensive pressure, game status, and offensive tactical strategies on shot success. Results: The results showed that paint clutch shots (63.9% success) were significantly more effective …

Health Effects Of Cadmium And Manganese Exposure On Luteinizing Hormone Levels: A Pilot Study Of Female Infertility, Shatha F. Alhous, Anees A. Al-Hamzawi, Murtadha Sh. Aswood

Al-Bahir

Female infertility occurs for many reasons, some unknown. Exposure to heavy metals is a risk factor that negatively impacts on female reproductive system. Therefore, this study aimed to evaluate the effect of cadmium Cd and manganese Mn on luteinizing hormone LH levels for females’ infertility. This study included a healthy group (n = 20), primary infertile females (n = 40), and secondary infertile females (n = 20) collected from Al-Zahraa hospital in Najaf center, Iraq. The Atomic Absorption Spectroscopy (AAS) was used to measure the cadmium and manganese concentrations and LH levels were measured by a Maglumi 800 from Snibe …

Enacting Tension: A Phenomenological, Art-Based Study Of Nicu Siblings’ Lived Experience Through Engagement With Dramatic Reality, Rebecca A. Versaci

Expressive Therapies Dissertations

A Neonatal intensive care unit (NICU) hospitalization reorganizes family life, yet siblings’ perspectives are rarely centered in NICU research. This phenomenological, art-based dissertation explores NICU siblings’ lived experience as revealed through the roles they created during engagement in dramatic reality. Eight child siblings of NICU patients participated in a storymaking and improvisational role-play intervention. Transcripts, participant artwork, and stories were examined through thematic analysis, and dramaturgical coding. Three central tensions organized children’s dramatic worlds: It’s Hard to be Together and It’s Hard to be Apart, I Want to be Free, but I am Trapped; I Want to Help …

Systemic Immunometabolic Profiling Classifies Cisplatin Sensitivity States Using Interpretable Machine Learning., Emily Klonoski, Diane C Lim, Yujie Wang, Edison Q Kim, Chunjing Wu, Ankita Paul, Cheng-Bang Chen, Medhi Wangpaichitr

PCOM Scholarly Works

Cisplatin resistance limits the effectiveness of platinum-based chemotherapy for lung adenocarcinoma, yet practical systemic diagnostics for cisplatin sensitivity are lacking. We developed ImmunoMetabolic Profiling Analysis and Classification Tool (IMPACT), an interpretable machine learning pipeline that selects the best performing model and reduces it to a minimal, mechanistically informative feature set via recursive feature elimination. In a syngeneic orthotopic model, we quantified 25 serum amino acids and 16 immune cell populations across bone marrow, spleen, lung, and mediastinal lymph nodes to capture systemic immunometabolic states. IMPACT classified cisplatin-sensitive versus cisplatin-resistant tumors with high accuracy (AUC = 0.950), driven primarily by bone …

Implementing Staff Education To Improve Depression Detection In Primary Care Using Patient Health Questionnaire (Phq-9), Ukamaka Okeke

Walden Dissertations and Doctoral Studies

This staff education project focuses on improving depression detection in a primary care settings using Patient Health Questionnaire (PHQ-9) screening tool. Depression is a leading cause of disability worldwide, requiring reliable and adaptable screening tools. The diagnosis of depression is one of the most common mental health disorders in primary care but is poorly identified and frequently missed. The lack of consistent screening for depression among patients often results in delayed identification of symptoms, which postpones early treatment, increasing the risk of complications associated with untreated depression. The practice site identified that depression screening was frequently missed during patient intake, …

First Epidemiological Assessment: Syphilis Seroprevalence Among Asymptomatic Blood Donors In Merowe, Northern Sudan, 2022, Doaa Albagir Ahmed, Sabra Alfadil Ibrahim, Hiba Elsadig Salah, Hamad A. Albagir

Saudi Toxicology Journal

Syphilis remains a significant transfusion-transmissible infection, yet regional epidemiological data from Northern Sudan are lacking. This study aimed to establish preliminary baseline syphilis seroprevalence among asymptomatic blood donors in Merowe, Northern Sudan. A cross-sectional study was conducted in January 2022 at the Merowe blood donation center. Eighty-nine consecutive asymptomatic male blood donors were screened for anti-Treponema pallidum antibodies using a commercial Enzyme-Linked Immunosorbent Assay (ELISA) kit (Fortress Diagnostics, UK). Demographic data were collected via structured questionnaire. The overall seroprevalence was 2.25% (2/89; 95% CI: 0.6–7.9%). The donor population median age was 32 years (range: 18–64). Both reactive donors were referred …

Rapid Resolution Of Psoriatic Arthritis Symptoms Following Initiation Of A Glp-1 Receptor Agonist, Joseph E. Capito, Kate Gelman

Faculty & Staff Scholarship

Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) are widely used for the management of type 2 diabetes mellitus (T2DM) and obesity, with growing evidence of their anti-inflammatory effects. We report the case of a 54-year-old woman with obesity, T2DM, and biopsy-confirmed plaque psoriasis who developed joint pain and stiffness consistent with psoriatic arthritis (PsA). Her symptoms persisted despite appropriate trials of topical corticosteroids, calcipotriene, and oral apremilast. She also declined methotrexate due to concerns about side effects. Imaging of her hands revealed distal interphalangeal joint space narrowing, marginal erosions, and periosteal reaction, supporting the diagnosis of PsA. The patient was …