Digital Commons Network^™

Ketamine For Active-Duty Military And Veterans With Ptsd, Kristopher Flynt

Physician Assistant Scholarly Project Posters

The purpose of this research and systematic literature review is to compare the drug ketamine’s efficacy at treating post-traumatic stress disorder for veterans and active-duty military compared to approved Food and Drug Administration (FDA) options and combination medication/psychotherapy. In this review, three databases were searched including Pubmed, ClinicalKey, and PsycInfo from October 3 to January 9, 2023. Additionally, the Veterans Affairs (VA)/Department of Defense (DOD) Clinical Practice Guidelines was utilized. A variety of key and mesh terms were utilized when database searching. Chosen works for review included randomized control trials, systematic reviews, meta-analysis, and retro-perspective studies. Sources that were excluded …

Where Do We Draw The Line? The Ethical Dilemma Involved In Genetic Engineering And Gene Therapy, Amber Schrag

Senior Honors Theses

Genetic engineering and gene therapy are greatly disputed in our time. With the advancement of technology, one has the power to manipulate genes in the body, which raises the questions: What is our role in this? Is there a limit to this power, or should there be? This paper reviews the uses of this technology and evaluates the ethics from a scientific and Biblical point of view. It is concluded that using gene therapy to help cure diseases is very beneficial in both the scientific and Biblical realm as it is restoring individuals back to health and wholeness.

Psychopathology Or Possession: How Ghanaian Pentecostal And Charismatic Christians Understand Mental Illnesses And How Perceived Understandings Vary Depending On If They Are Current Students Or Not, Jamila L. Taffe

Independent Study Project (ISP) Collection

This research investigates the perceptions held by Ghanaian Chrsitians from Pentecostal/Charismatic churches about mental illnesses. The data collected was done through a qualitative method of acquiring information. Interviews were conducted alongside intensive research of existing scholarship that addressed religion and mental health within Ghanaian culture. A total of 5 in depth interviews were carried out with participants ranging from the ages of 20-35. Three participants were current university students at the University of Ghana while the other two were non-students but held degrees. The objective was to make comparisons between the student and non-student groups about their knowledge about mental …

Moral Injury To Inform Analysis Of Post-Traumatic Stress Disorder, Amanda Julia Manea

Senior Theses

Post-traumatic stress disorder (PTSD) is a mental health condition that almost one out of ten veterans struggle with. Although the National Center for PTSD has made extensive progress in characterizing and developing new treatments for PTSD, most veterans still experience symptoms of PTSD following treatment. Novel avenues of investigation, such as developing algorithms to review electronic health record (EHR) data and better understanding moral injury, are being pursued to address the gap that still exists when it comes to treating veterans. Moral injury is the individual evaluation of exposure to a potentially morally injurious event (PMIE) and can lead to …

Conjugation's Toolkit: The Roles Of Nonstructural Proteins In Bacterial Sex, Matthew B Cooke, Christophe Herman

Faculty, Staff and Students Publications

Bacterial conjugation, a form of horizontal gene transfer, relies on a type 4 secretion system (T4SS) and a set of nonstructural genes that are closely linked. These nonstructural genes aid in the mobile lifestyle of conjugative elements but are not part of the T4SS apparatus for conjugative transfer, such as the membrane pore and relaxosome, or the plasmid maintenance and replication machineries. While these nonstructural genes are not essential for conjugation, they assist in core conjugative functions and mitigate the cellular burden on the host. This review compiles and categorizes known functions of nonstructural genes by the stage of conjugation …

Ic090: Ken Mattox Interview, Transcript, Friends Of The Texas Medical Center Library

2023 Oral History Project

See more at Friends of the Texas Medical Center Library Records and its finding aid.

Method Development Biological Agent Personal Decontamination Effectiveness For Airman Battle Uniform Fabric Material: Ms2 Bacteriophage, Alisha Helm

Theses and Dissertations

This article presents a study that investigates the effectiveness of a common decontamination (decon) strategy used by Airmen in the United States Air Force who may find themselves in a densely populated area during an emergency evacuation. Ultimately, this study addresses the following questions: Is there a significant difference in the number of viral particles being re-aerosolized before and after the applied decon strategy, and is this difference significant enough to consider the decon strategy effective? The study entails using MS2 bacteriophage to contaminate swatches of Airman Battle Uniform (ABU) fabric. Swatches were secured to a vortex centered in the …

Effects Of Occupationally Military-Relevant Particle Mixtures (Sio2, Cdo, Cr2O3) On A549 Human Pulmonary Epithelial Cells, Isabella M. Muffoletto

Theses and Dissertations

In the course of maintaining a safe, mission-ready aircraft fleet and operational runways, United States Airmen experience a range of occupational risks. These risks include inhalable hazards generated from oft-used maintenance practices, such as blasting which emits silica from the media abrasives as well as contaminants from the exterior coatings. Additional inhalation hazards range from engine and fuel emissions, chemical agents, radiation, and explosives, to naturally occurring and human-manufactured biopathogens. Of notable concern are emissions in forward-deployment areas, including urban pollution, particulates released from runway construction and maintenance activities, and combustion from burn pits containing hazardous and unknown combinations of …

Entry Receptors - The Gateway To Alphavirus Infection, Ofer Zimmerman, Autumn C. Holmes, Natasha M. Kafai, Lucas J. Adams, Michael S. Diamond

2020-Current year OA Pubs

Alphaviruses are enveloped, insect-transmitted, positive-sense RNA viruses that infect humans and other animals and cause a range of clinical manifestations, including arthritis, musculoskeletal disease, meningitis, encephalitis, and death. Over the past four years, aided by CRISPR/Cas9-based genetic screening approaches, intensive research efforts have focused on identifying entry receptors for alphaviruses to better understand the basis for cellular and species tropism. Herein, we review approaches to alphavirus receptor identification and how these were used for discovery. The identification of new receptors advances our understanding of viral pathogenesis, tropism, and evolution and is expected to contribute to the development of novel strategies …

An Efficient Hash-Based Assessment And Recovery Algorithm For Distributed Healthcare Systems, Sanaa Kaddoura, Ramzi Haraty, Sultan Al Jahdali, Mohamad Jaber

All Works

The enhancement of the information technology in many domains has had a positive impact on the healthcare sector. The ability to share medical data is one of the positive outcomes. However, this improvement comes with a number of threats. Although many threat preventive measures have been applied yet, no one can be confident that the system is safe from attacks. Thus, an algorithm needs to assess the damage occurring as a result of an attack before recovering the database. In this work, we present a distributed algorithm that uses hash tables to deal with the “information warfare” problem in healthcare …

Excretory/Secretory Proteome Of Females And Males Of The Hookworm Ancylostoma Ceylanicum, Samuel C Uzoechi, Bruce A Rosa, Kumar Sachin Singh, Young-Jun Choi, Bethany K Bracken, Paul J Brindley, R Reid Townsend, Robert Sprung, Bin Zhan, Maria-Elena Bottazzi, John M Hawdon, Yide Wong, Alex Loukas, Sergej Djuranovic, Makedonka Mitreva

Faculty, Staff and Students Publications

The dynamic host-parasite mechanisms underlying hookworm infection establishment and maintenance in mammalian hosts remain poorly understood but are primarily mediated by hookworm’s excretory/secretory products (ESPs), which have a wide spectrum of biological functions. We used ultra-high performance mass spectrometry to comprehensively profile and compare female and male ESPs from the zoonotic human hookworm Ancylostoma ceylanicum, which is a natural parasite of dogs, cats, and humans. We improved the genome annotation, decreasing the number of protein-coding genes by 49% while improving completeness from 92 to 96%. Compared to the previous genome annotation, we detected 11% and 10% more spectra in …

Excretory/Secretory Proteome Of Females And Males Of The Hookworm Ancylostoma Ceylanicum, Samuel C Uzoechi, Bruce A Rosa, Kumar Sachin Singh, Young-Jun Choi, Bethany K Bracken, Paul J Brindley, R Reid Townsend, Robert Sprung, Bin Zhan, Maria-Elena Bottazzi, John M Hawdon, Yide Wong, Alex Loukas, Sergej Djuranovic, Makedonka Mitreva

2020-Current year OA Pubs

The dynamic host-parasite mechanisms underlying hookworm infection establishment and maintenance in mammalian hosts remain poorly understood but are primarily mediated by hookworm's excretory/secretory products (ESPs), which have a wide spectrum of biological functions. We used ultra-high performance mass spectrometry to comprehensively profile and compare female and male ESPs from the zoonotic human hookworm

Veteran Access To Mental Health Services And How It Contributes To The Rates Of Suicide, Kameron R. Grigsby

Kentucky Journal of Undergraduate Scholarship

This essay is an exploration of the access Veterans have to mental health services and how such access or lack thereof contributes to the rates of suicide among the Veteran population. The purpose of this essay is to examine various factors that influence Veteran access to mental health care and how these factors can be improved or eliminated. By analyzing such factors, healthcare professionals may begin to further implement provisions and practices to decrease the rising rate of suicides among Veterans.

Tularemia Seroprevalence In Humans In The Region Of The Hittite-Arzawa War (Inner Aegean Region), Where The First Biological Weapon Was Used 3300 Years Ago, İsmai̇l Davarci, Canan Eryildiz, Duygu Perçi̇n Renders, Ufuk Berberoğlu, Şaban Gürcan

Turkish Journal of Medical Sciences

Background/aim: According to Egyptian records, tularemia emerged in the Canaan region, where it was first identified and spread to Anatolia over the Euphrates. It was used as an active biological weapon for the first time in the Hittite-Arzawa War in 1320-1318 BC. This study aimed to investigate the seroprevalence of tularemia in the Inner Aegean Region, which is thought to be the region where this war was fought 3300 years ago. Materials and methods: Tularemia seropositivity in humans was investigated in 27 villages/neighborhoods in 3 districts in each of Manisa, Kütahya, and Uşak provinces. Before the study, the participants were …

Understanding Inflammation, Immunity, And Infection, Jeff Vasiloff, Md, Mph

OHIO Open Faculty Textbooks

Inflammation, immunity, and infection explained by Jeffrey Vasiloff, MD, MPH, Associate Clinical Professor, PA Program; Adjunct Professor, PT Program, College of Health Sciences and Professions, Ohio University Dublin Medical Campus; Physician Consultant: Ohio Association of Physician Assistants; Physician Volunteer: Franklin County & Columbus Medical Reserve Corps; Board Certification: Internal Medicine & Diabetes and Endocrinology.

The Essence Of Therapeutic Relationships In Equine-Assisted Psychotherapy, Joy Clark Akin

Walden Dissertations and Doctoral Studies

AbstractTraditional psychotherapeutic approaches are not always effective in alleviating psychological symptoms and improving functioning in young adults. Equine-assisted psychotherapy (EAP) has been shown as a beneficial alternative therapeutic method developed for clients not helped by traditional methods. However, the essence of the therapeutic relationship that develops between the client, horse, therapist, and equine specialist has not been explored. The purpose of this phenomenological study was to explore the lived experience of the therapeutic relationship in young adults who participated in EAP. The frameworks of person-centered theory and self psychology guided the development of interview questions, data analysis, and interpretation. Four …

Journal Of The Arkansas Academy Of Science Volume 77, Academy Editors

Journal of the Arkansas Academy of Science

No abstract provided.

Moral Injury Themes Involving Criminal Recklessness Among Adults With Alcohol Use Disorder, Sandra Starch

Walden Dissertations and Doctoral Studies

Moral injury (MI) can emerge following transgressive acts against one’s deeply held moral beliefs. Its symptomology involves individual psychological, spiritual, behavioral, and social spheres. It has primarily been studied within the military and in a few select civilian populations. This descriptive phenomenological study involved exploring MI themes among adults with alcohol use disorder (AUD) who had engaged in criminally reckless acts. Data collected from semi-structured interviews with eight participants were coded and analyzed, leading to six major themes revealing the symptomology of MI. Responses from study participants supported Festinger’s theory of cognitive dissonance via their descriptions of alcohol abuse cycles …

International Academic Partnerships In Orthopaedic Surgery, Michael Jesse Flores

Yale Medicine Thesis Digital Library

Abstract: INTERNATIONAL ACADEMIC PARTNERSHIPS IN ORTHOPAEDIC SURGERY. Michael J. Flores. Department of Orthopaedics & Rehabilitation, Yale University, School of Medicine, New Haven, CT.

Introduction: Orthopaedic-related disease (ORD) is one of the leading health challenges faced worldwide and is a significant cause of global morbidity and mortality, especially in low- and middle-income countries (LMICs). In recent years, international orthopaedic outreach to address the global burden of ORD has received greater attention due to initiatives such as the Lancet Commission on Global Surgery (LCGS). Many strategies have been considered to address the global burden of ORD, most commonly though volunteer trips by …

Comparison Of Midwifery And Obstetric Care Among American Indian And Alaska Native Birthing People, Trista Barnhart

All Master's Theses

Despite making up only 3% of the U.S. population, American Indian/Alaska Native (AI/AN) individuals have the second highest maternal mortality rate in the United States, and the leading cause of maternal mortality and morbidity among AI/AN is postpartum hemorrhage. Many interventions used during childbirth have been identified as common causes of hemorrhage, such as lacerations of the vagina and cervix, operative vaginal deliveries, & augmentation of labor. Research has found that individuals who had midwives as their care providers have been found to be less likely to experience instrumental deliveries, epidural analgesia, labor augmentation, episiotomy or perineal lacerations, cesarean sections, …

Commentary On Healthcare And Disruptive Innovation, Hilary Finch, Affia Abasi-Amefon, Woosub Jung, Lucas Potter, Xavier-Lewis Palmer

Electrical & Computer Engineering Faculty Publications

Exploits of technology have been an issue in healthcare for many years. Many hospital systems have a problem with “disruptive innovation” when introducing new technology. Disruptive innovation is “an innovation that creates a new market by applying a different set of values, which ultimately overtakes an existing market” (Sensmeier, 2012). Modern healthcare systems are historically slow to accept new technological advancements. This may be because patient-based, provider-based, or industry-wide decisions are tough to implement, giving way to dire consequences. One potential consequence is that healthcare providers may not be able to provide the best possible care to patients. For example, …

National Emissaries For Preventive Healthcare. Visiting Nurses In Interwar Bulgaria And Yugoslavia, Evguenia Davidova

History Faculty Publications and Presentations

In the interwar period, as part of a wholesale reorganization of public healthcare, Bulgaria and Yugoslavia saw the emergence of a new healthcare protagonist: the visiting nurse. Grounded in archival materials, by means of an analysis that intertwines gender and class, this article argues that the visiting nurse became a crucial (and cheaper) link between the hospital and the home in the fight against social diseases and reducing child mortality. These social interactions were often mediated by international humanitarian organizations. In this context, the visiting nurse serves as another bridge—this time between national and international public health policies. Visiting nurses …

Dispersal Of Blackbird Flocks From Sunflower Fields: Efficacy Influenced By Flock And Field Size But Not Drone Platform, Conor C. Egan, Bradley Blackwell, Esteban Fernández‐Juricic, Page Klug

United States Department of Agriculture Wildlife Services: Staff Publications

Crop depredation by blackbirds (Icteridae) results in substantial economic losses to the United States sunflower industry, and a solution to effectively reduce damage remains elusive. We evaluated the utility of uncrewed aircraft systems (UAS), or drones, as hazing tools to deter foraging blackbirds from commercial sunflower (Helianthus annuus) fields in North Dakota, USA, between September and October 2017. We compared the efficacy of 3 drones: a fixed‐wing predator model mimicking the form of an aerial raptor, a fixed‐wing airplane of similar size, and a multirotor drone. Multirotor drones are relatively easy to fly and are a multifunctional tool for agricultural …

The Influence Of Personal Traits, Individual Behaviours And Population Health Determinants On The Epidemiology Of Facial Injury: Psychiatric Comorbidity, Substance Abuse, Sars Social Distancing Measures, Gary Russell Hoffman

Theses

ABSTRACT Introduction Injury can be defined as an act or event that causes harm, hurt or damage. It occurs as a result of the transfer of energy to living tissue. The biological response to such an insult is inflammation and is based on the activation of immune competent cells in tandem with alterations in vascular permeability. The process is orchestrated at a subcellular level by the release of immunomodulatory molecular mediators. T

he bones of the skull and face are the key determinant of human appearance. They form the framework to which other tissues are attached. The variability of facial …

“To Live In The Body Of A Survivor ”: Unique And Cumulative Disaster Exposure And Mental Health In A Sample Of Hurricane Katrina Survivors, Noelle Serino

Public Health Theses

Introduction: Fueled by the escalation of climate change, weather-related disasters are increasing in frequency and severity. Existing research has documented the extensive harm induced by such disasters, yet few studies have examined how individuals’ psychological well-being fares when exposed to multiple, diverse threats, including other weather-related and public health disasters (e.g., COVID-19). As such, the present study explores posttraumatic and psychological distress in the context of unique and cumulative disaster exposure.Methods: The data utilized for this study came from the Resilience in Survivors of Katrina (RISK) Project. The sample was comprised of 381 predominantly Non-Hispanic Black (84.5%) women who experienced …

The Essence Of Therapeutic Relationships In Equine-Assisted Psychotherapy, Joy Clark Akin

Walden Dissertations and Doctoral Studies

AbstractTraditional psychotherapeutic approaches are not always effective in alleviating psychological symptoms and improving functioning in young adults. Equine-assisted psychotherapy (EAP) has been shown as a beneficial alternative therapeutic method developed for clients not helped by traditional methods. However, the essence of the therapeutic relationship that develops between the client, horse, therapist, and equine specialist has not been explored. The purpose of this phenomenological study was to explore the lived experience of the therapeutic relationship in young adults who participated in EAP. The frameworks of person-centered theory and self psychology guided the development of interview questions, data analysis, and interpretation. Four …

Biocybersecurity And Deterrence: Hypothetical Rwandan Considerations, Issah Samori, Gbadebo Odularu, Lucas Potter, Xavier-Lewis Palmer

Community & Environmental Health Faculty Publications

Digitalization and sustainability are popular words within modern disciplines as practitioners each look toward the future of their respective fields. Specifically for the African continent, which is making great strides in developmental targets, those two terms are central to core aspects of policy initiatives that may foster cooperation across its varied lands and nations. One of the underlying challenges that confront Africa is a lack of strong regional integration across socioeconomic and political programs; there is value in African regions having more regional connectedness. We assess the rate of regional integration and development in Africa and discuss how to alleviate …

The Rayleigh Problem (Random Flights) Is Everywhere Redux, John E. Gray, Stephen R. Addison

Journal of the Arkansas Academy of Science

The phase noise problem (or Rayleigh problem) occurs in all aspects of radar. It is an effect that a radar engineer or physicist always has to take into account as part of a design or in an attempt to characterize the physics of a problem such as reverberation. Normally, the mathematical difficulties of phase noise characterization are avoided by assuming the phase noise probability distribution function (PDF) is uniformly distributed, and the Central Limit Theorem (CLT) is invoked to argue that the superposition of relatively few random components obey the CLT and hence the superposition can be treated as a …

Moral Injury Themes Involving Criminal Recklessness Among Adults With Alcohol Use Disorder, Sandra Starch

Walden Dissertations and Doctoral Studies

Moral injury (MI) can emerge following transgressive acts against one’s deeply held moral beliefs. Its symptomology involves individual psychological, spiritual, behavioral, and social spheres. It has primarily been studied within the military and in a few select civilian populations. This descriptive phenomenological study involved exploring MI themes among adults with alcohol use disorder (AUD) who had engaged in criminally reckless acts. Data collected from semi-structured interviews with eight participants were coded and analyzed, leading to six major themes revealing the symptomology of MI. Responses from study participants supported Festinger’s theory of cognitive dissonance via their descriptions of alcohol abuse cycles …

The Monroe Method: A Methodology On Navigating Race, Oppression, And Equity In Medical Education Through Physician Cultural Responsibility, Christen D. Johnson

Antioch University Dissertations & Theses

Many forms of oppression create barriers for health care, further health disparities, and impact the wellness of physicians. As health disparities, caused by the social determinants of health, complicate the practice of medicine, physicians’ risk of burnout increases. The practice of Physician Cultural Responsibility provides a means to overcome health disparities and support physicians while embracing the intersectionality of the populations they serve. Incorporation of Physician Cultural Responsibility into physician professional identity is essential for the practice to be life-long. As there is no standardized curriculum to address teaching the practice of Physician Cultural Responsibility, this study aims to evaluate …