Digital Commons Network^™

Interactions Between Murine Peritoneal Macrophages And Naegleria Fowleri, Leigh Ann Belcher

Theses and Dissertations

In the present study, we have examined the differences among Corynebacterium parvum-activated, thioglycollate-elicited, and resident macrophages from (C57BL/6 X C3H)F1 mice utilizing two microcytotoxicity assays. Macrophage and Naegleria fowleri were interchangeably employed as effector and target cells. To assess the ability of the macrophage to lyse N. fowleri, the amoebae were labeled with 5 μCi of 3H-uridine per 5 x 10^5 cells for 18 h prior to co-culturing with adherent macrophage monolayers. Although the macrophage-induced lysis was density and time dependent, C. parvum macrophages consistently demonstrated an increased cytotoxic response to N. fowleri after 24 h co-incubation at a 10:1 …

Synthesis Of Mesoionic Nucleosides As Potential Antineoplastic Agents, Shanaz Mohammedali Tejani

Theses and Dissertations

During the past few decades, analogs of purine nucleosides have been described that are modified either in the heterocyclic base, sugar moiety or both, and many of these modified nucleosides display antiviral and/or antineoplastic activity. The Class II mesoionic purinones are isosteric with their non~mesoionic purinone counterparts. It is conceivable that the mesoionic purinone nucleosides might constitute an entirely novel class of modified nucleosides with potential chemotherapeutic activity. That the mesoionic heterobases are bioisosteric as well as isosteric with non-mesoionic purinones was realized by demonstrating that certain mesoionic xanthine derivatives, such as Anhydro-8-ethylw-5-hydroxy-7-oxo-l,3,4-thiadiazolo[3,2-a]pyrimidinium hydroxide and Anhydro-6-p-chlorobenzyl-8-ethyl-5-hydroxy-7-oxo—l,3,4—thiadiazolo [3,2-a]pyrimidinium hydroxide were comparable …

The Relationship Of Sex Role Self Concept And Role Conflict In Female Nursing Administrators, Charlotte B. Hoelzel

Theses and Dissertations

This study investigated the relationship between the sex role self concept of female nursing administrators and the role conflict they experienced. The correlation of age. education and experience with sex role self concept and role conflict was examined. This was a descriptive survey with a purposive probability sample of 126 subjects from three mid-Atlantic states. A mail survey resulted in a useful return of 88 questionnaires, including 81 females.

The Bem Sex Role Inventory was utilized to measure sex role self concept; masculinity and femininity are viewed as two independent dimensions present in every individual. Role conflict was measured by …

The Effects Of Learning Assistance On A Selected Group Of Nursing Students, Bernice R. Metcalf

Electronic Theses and Dissertations

The purpose of this study was to assess the effectiveness of learning assistance on the success of provisionally admitted students in an associate degree nursing program as evaluated by nursing course grades and State Board Test Pool Examination results. Knowles'• Theory of Aridxagogy and a construct, of • Bloom's Mastery Learning served as the conceptual framework for the study.
The sample was 20 students provisionally admitted to an associate degree program in a state supported college in the Pacific Northwest. A quasi-experimental research design, using both non-equivalent control groups and a matched group, was utilized.
The study posed 15 null …

Force Measurement And Design Of A Torquing Highpull Headgear, John William Tabash

Master's Theses

No abstract provided.

Cerestore Alumina Ceramic: Intra-Coronal Cavity Design And Efficacy, Nasreddin A. Takally

Master's Theses

No abstract provided.

Pharmacokinetics And Protein Binding Of Morphine In Horses, Joan Combie, Thomas E. Nugent, Thomas Tobin

Maxwell H. Gluck Equine Research Center Faculty Publications

Morphine could be detected in horses dosed with 0.1 mg of drug/kg of body weight for up to 48 hours in blood and 144 hours in urine. This dose of morphine elicited no observ­able effects and is a suggested an­algesic dose. Computer analysis revealed that a 3-compartment open system was the best fitting model with a serum half life of 87.9 minutes and a urine half life of 101.1 minutes. Binding to equine serum proteins was linear over a drug con­centration range of 3.88 x 10-5M to 3.50 x 10-aM and averaged 31.6%. In RBC-partitioning experiments, 78.1 % of the …

Oncolog, Volume 28, Number 01, January-March 1983, The University Of Texas Md Anderson Cancer Center, James M. Bowen Phd

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Newsletter Becomes OncoLog
• Prolactinoma, a Prevalent Gonadoinhibitory Tumor, Responds Well to Treatment
• Laboratory Research Continues to Advance Methods of Cancer Diagnosis and Therapy
• Radiotherapy Plays Vital Role in Treatment or Patients with Malignant Parolld Tumors

Oncolog, Volume 28, Number 04, October-December 1983, Christopher J. Logothetis Md, Melvin L. Samuels Md, Andrew C. Von Eschenbach Md, Antonio Trindade Md, Sheryl Ogden Bsn, Cindy Grant Bs, Douglas E. Johnson Md, Helmuth Goepfert Md, Jordan U. Gutterman Md, William J. Dichtel Md, Roy B. Sessions Md, Ayten Cangir Md, Marcelle Sulek

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Implant Relieves Chronic Pain, Delivers Drug Directly to Central Nervous System
• New Drug Combination Improves Survival For Patients with Metastatic Prostate Cancer
• Leukocyte Interferon Inhibits Growth Of Virally Related Laryngeal Tumor

The Human Environment: Penultimate Problems Of Survival, Robert William Kates

FMHI Publications

No abstract provided.

Wrongful Life And Wrong Rules: Abuse Of The Normal Range Concept, James W. Winkelman

Syracuse Scholar (1979-1991)

James W. Winkelman, M.D., is Professor of Pathology and Director of Laboratories at the State University of New York Upstate Medical Center. Despite the tempering influence of education at the University of Chicago (B.A.) and the Johns Hopkins University School of Medicine (M.D.), he is inclined to become embroiled in topics just beyond his primary expertise. This exercise in law and government developed from personal experiences.

Intimations Of Immorality: Clones, Cyrons And The Law, George P. Smith Ii

Scholarly Articles

This article examines some legal and moral issues associated with two developing areas of biomedicine; cloning and cryonics. The author firstly considers the practical benefits to society of developing perfecting and utilizing the process of cloning. These include the ability to overcome inheritable genetic defects and the provision of organs for transplantation. Against this must be weighed some moral and ethical problems of genetic engineering. Professor Smith then discusses the process of deep-freezing a person and the development of cryonics as a social movement. The major legal problem stemming from cryonics is determining the time at which a cryonically suspended …

Access To Care; Series Ii; File 1, Juanita Hunter

Juanita Hunter, RN & NYSNA Papers [1973-1990]

No abstract provided.

Vital Signs, Winter 1983, Boonshoft School Of Medicine

Vital Signs

A twenty eight page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Outlook Magazine, Spring 1983

Outlook Magazine

No abstract provided.

Outlook Magazine, Summer 1983

Outlook Magazine

No abstract provided.

Gene Locus For Α₁-Antitrypsin (Pi) Assigned To Human Chromosome 14, Stephen J. Pearson

Yale Medicine Thesis Digital Library

No abstract provided.

Serial Cardiovascular Adaptations During Pregnancy, Mark Vincent Hart

Dissertations and Theses

Maternal cardiovascular adaptations appear to be essential in order to supply extra circulation to both the developing fetus and maternal system during a successful pregnancy. Since inadequate cardiovascular adjustments may produce abortions or maternal morbidity, the characterization of maternal cardiovascular changes during pregnancy and the elaboration of the underlying mechanism for these changes are essential to the understanding of how the heart enlarges during pregnancy and what significance this enlargement might have. To provide needed information regarding this time course and extent of maternal cardiac enlargement and the hormonal and hemodynamic changes which may be responsible for these changes, the …

The Absence Of Extrachromosomal Dna In Methanogenic Bacteria, Nancy Ann Kurkinen

Dissertations and Theses

Five species of methanogenic bacteria were analyzed for the presence of plasmid DNA. Several procedures for the detection and isolation of covalently closed circular plasmid DNA were modified for use with the methanogens.

The Utilization Of Response Surface Techniques In Survival Experiments, Leonard Edward Buchner

MUSC Theses and Dissertations

Linear regression procedures are described which give an unbiased estimate of the percent functional viability of rat polymorphonuclear leukocytes (PMN's). These statistical techniques allow discrimination between variables which result in increased PMN survival after freezing. A review of current response surface techniques was made as they relate to optimizing the functional viability of PMN's after freezing. Experimental designs based on the steepest ascent and simplex methodologies were considered. Since the hill climbing efficiency of the steepest ascent and simplex methods are comparable, the steepest ascent procedure was selected as it is more readily adaptable to a batch mode analysis.

J Am Coll Dent 1983 50 2

Journal of the American College of Dentists

The Journal of the American College of Dentists (JACD) publishes scholarly articles, editorials, essays, and reflections addressing the ethical, professional, and social dimensions of dentistry. The Journal serves as a forum for advancing ethics, professionalism, leadership, and excellence within the dental community. By fostering dialogue across disciplines and perspectives, JACD provides readers with insights that encourage ethical, professional practice, lifelong learning, and service to the public, reinforcing dentistry’s commitment to advancing oral healthcare and the common good.

A Correlation Of Subjective Ranking Of Facial Esthetics And The Golden Section Analysis, Timothy Robin York

Loma Linda University Electronic Theses, Dissertations & Projects

The objective of this study was to determine if faces which fit the golden sections as proposed by Ricketts were considered more esthetic to the layman than faces which did not fit the golden sections as well.

Frontal facial photographs of 92 individuals from the normal occlusion sample of Andrews were measured for facial proportions according to Ricketts application of the golden section. Seven facial proportions were computed from the photographs. Ten photographs were selected, five of males and five of females, representing a range of mean percent deviation from the golden section proportion (1.618). Randomly arranged sets of these …

An Investigation Into The Cellular And Humoral Organization Of The Thymic Microenvironment, Howard R. Higley

Dissertations

No abstract provided.

A Comparative Study Of Value Orientations In American Society, Mexican Society, And High School Students, Stanley A. Sliwiak

Dissertations

No abstract provided.

Virginia Dental Journal (Vol. 60, No. 1, 1983)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 60, No. 6, 1983)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 60, No. 2, 1983)

Virginia Dental Journal

No abstract provided.

Interaction Of Phosphatidylserine-Phosphatidylcholine Liposomes With Sickle Erythrocytes. Evidence For Altered Membrane Surface Properties, R. S. Schwartz, Nejat Düzgüneş, D. Tsun Yee Chiu, B. Lubin

All Dugoni School of Dentistry Faculty Articles

The sickle erythrocyte (RBC) is a pathologic RBC that contains multiple membrane abnormalities. Some of these abnormalities have been implicated in the pathophysiology of vasoocclusive crises characteristic of sickle cell disease; others have yet to be defined in terms of their clinical significance. Recent information has shown that sickle RBC adhere abnormally to cultured endothelial cells yet little is known about the ways in which sickle cells interact with model membranes of defined size and lipid composition. We investigated this phenomenon by interacting sickle RBC with artificial lipid vesicles (liposomes) containing acidic phospholipids. Our results demonstrate that sickle disease (hemoglobin …

Expression Of A Streptococcus Mutans Glucosyltransferase Gene In Escherichia Coli, James P. Robeson, Raul G. Barletta, Roy Curtiss Iii

School of Veterinary and Biomedical Sciences: Faculty Publications

Chromosomal DNA from Streptococcus mutans strain UAB90 (serotype c) was cloned into Escherichia coli K-12. The clone bank was screened for any sucrosehydrolyzing activity by selection for growth on raffinose in the presence of isopropyl- β-D-thiogalactoside. A clone expressing an S. mutans glucosyltransferase was identified. The S. mutans DNA encoding this enzyme is a 1.73-kilobase fragment cloned into the HindIII site of plasmid pBR322. We designated the gene gtfA. The plasmid-encoded gtfA enzyme, a 55,000-molecular-weight protein, is synthesized at 40% the level of pBR322-encoded β-lactamase in E. coli minicells. Using sucrose as substrate, the gtfA enzyme catalyzes …

Namru-3 Translations Of Parasite Literature From Russian, French, Japanese, Etc. Into English (1915-1983) T1601-T1700, United States Naval Medical Research Unit Number Three, Cairo, Medical Zoology Department

United States Naval Medical Research Unit 3: Publications

T1603. TRANSLATION FROM RUSSIAN. SELIVANOV, Ya. M. and POLYAKOVA, A. N. (1981). Technic of preparing and producing experimental series of immunoglobulin erythrocytic polytype diagnosticums to certain arboviruses for the indirect hemagglutination test. Sborn. Trud. Inst. Virus. imeni D. I. Ivanovsky, Akad. Med. Nauk SSSR, pp. 145-151.

T1604. TRANSLATION FROM RUSSIAN. ROSLAYA, I. G., DEMENEV, V. A., PRYGOVA, A. I., ROSLYAKOV, G. E. and VERETA, L. A. (1981). Certain questions of ecology of tickborne encephalitis group viruses in the lower Pre-Amur'ye. Sborn. Trud. Inst. Virus. imeni D. I. Ivanovsky, Akad. Med. Nauk SSSR, pp. 90-94.

T1605. TRANSLATION FROM RUSSIAN. EMEL'YANOVA. N. …