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Distribution Of The Shoshone Scuplin (Cottus Greenei: Cottidae) In The Hagerman Valley Of South Central Idaho, Richard L. Wallace, J. S. Griffith Jr., D. M. Daley, Patrick J. Connolly, G. B. Beckham

Great Basin Naturalist

Cottus greenei, a potentially threatened species endemic to Idaho, was collected from 49 localities in 25 springs/streams in south central Idaho. Most localities were along the north bank of the Snake River in waters of the Thousand Springs formation, Gooding County. One population was found in a spring in the main Snake River. Another sculpin, Cottus bairdi, was collected with C. greenei at 23 locations in 16 springs/streams. Confusion concerning the type locality of Cottus greenei is discussed.>

Dr. Lionel Newsom Interview Conducted On April 11, 1984 About The Boonshoft School Of Medicine At Wright State University, Lionel Newsom, James St. Peter

Boonshoft School of Medicine Oral History Project

In this interview, Dr. Lionel Newsom, President of Central State University, traces and discusses the involvement of Central State University in the organization and development of the Wright State University School of Medicine. President Newsom also discusses Black community concerns with minority recruitment and involvement in the School of Medicine and the factors that have inhibited increased Central State University participation in the School of Medicine.

Raymond A. Palmer Interview Conducted On April 6, 1984 About The Boonshoft School Of Medicine At Wright State University, Raymond A. Palmer, James St. Peter

Boonshoft School of Medicine Oral History Project

In this interview, Mr. Raymond A. Palmer, first Health Sciences Librarian of the Wright State University School of Medicine, discusses the initial development and the first years of the Health Sciences Library. Particular attention is focused on his background, his coming to Wright State University, his initial activities and priorities as Health Sciences Librarian of a new School of Medicine, the development and growth of the Health Sciences Library, and his responsibilities and activities in the school and with the area hospitals. Important areas in the interview also include Mr. Palmer's perceptions of the overall School of Medicine development and …

Vital Signs, Spring 1984, Boonshoft School Of Medicine

Vital Signs

A twenty eight page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

The Relationship Between Thought Disorder And The Diagnosis Of Schizophrenia, David Frank Fatzinger

Dissertations

The diagnosis of schizophrenia has been considered unreliable, especially when derived by psychiatric interview. Thought disorder is one symptom that has been accepted by most clinicians as a major indicator of schizophrenia. The purpose of this study was to examine the relationship between thought disorder and the diagnosis of schizophrenia in a state hospital setting.

The sample consisted of 88 patients, 58 males (mean age = 32.0) and 30 females (mean age = 38.6) and was gathered from newly admitted patients in a large state hospital. Thought disorder was measured by the Whitaker Index of Schizophrenic Thinking (WIST) Form A, …

A Method For The Comparison Of Hdl Containing Apoprotein E And Hdl Cholesterol, Steven A. Knizner

Chemistry & Biochemistry Theses & Dissertations

Human serum high density lipoproteins (HDL) were isolated by preparative salt density gradient ultracentrifugation and analyzed further by heparin-sepharose affinity chromatography. Separation of the major classes of serum lipoproteins was achieved after a single ultracentrifugation on a salt density gradient at 272,000 x g for 36 hours in a swinging bucket rotor. After isolation, the total HDL was subdivided into HDL containing apoprotein E and HDL without this apoprotein by heparin-sepharose affinity chromatography. Relative amounts of these subclasses were then calculated.

HDL-cholesterol was measured after precipitation of LDL and VLDL by phosphotungstic acid and magnesium. The statistical relationship between HDL …

Investigation Of The Coenzyme Binding Site Of Lactate Dehydrogenase From Chicken Muscle, Jia-Hwei Lin

Chemistry & Biochemistry Theses & Dissertations

Investigation of the coenzyme binding site of lactate dehydrogenase was approached by using coenzyme analogs. Inhibition studies of this enzyme using n-alkylphosphates as coenzyme analogs were performed with a fluorometric method. The results showed that all of the n-alkylphosphates were competitive inhibitors with respect to NAD⁺.

The n-alkyl-ADPs were synthesized from AMP and dicycloheaylammonium salts of n-alkylphosphates. The synthetic compounds were subjected to NMR spectroscopic studies, thin layer chromatography and determination of the ratio of adenosine moiety to phosphate groups. The results indicated that the synthetic compounds were n-alkyl-ADPs.

These synthetic compounds were used as coenzyme analogs in …

Admissions Criteria As Predictors Of Students' Successful Completion Of A Dental Hygiene Program, M. Linda Brown

Dental Hygiene Theses & Dissertations

The purpose of this study was to investigate the criteria used to select dental hygiene students and to determine the ability of these criteria to predict students' successful completion of a dental hygiene program. One hundred sixteen graduates of the certificate level dental hygiene program at Old Dominion University between 1971- 1981, inclusive, comprised the sample. The majority of the subjects were Caucasian females, ages 20 to 24. The admissions criteria examined were (1) Dental Hygiene Aptitude Test scores, (2) Scholastic Aptitude Test scores, (3) preadmission quality point average, (4) college chemistry quality point average, and (S) percentile rank in …

Gamma Interferon Induces Monocytoid Differentiation In The Hl-60 Cell Line., Edward D. Ball, Paul M. Guyre, Li Shen, John M. Glynn, Charles R. Maliszewski, Paul E. Baker, Michael W. Fanger

Dartmouth Scholarship

We investigated the ability of purified, recombinant DNA-derived interferons (IFN) to induce phenotypic changes in cells of the HL-60 promyelocytic leukemia cell line. Changes in cell surface markers detected by monoclonal antibodies as well as morphologic, histochemical, and functional changes were monitored. We found that gamma-IFN, but not alpha- or beta-IFN, induced the expression of antigens characteristic of monocytes and granulocytes (AML-2-23, 63D3, and 61D3), as well as changes in morphology consistent with monocytoid differentiation. These included induction of alpha-naphthyl acetate esterase, increased cell size, and a decrease in azurophilic granules. The gamma-IFN dose dependency and time course of the …

Jefferson Alumni Bulletin – Volume Xxxiii, Number 3, Spring 1984

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XXXIII, Number 3, Spring 1984

Keeping the curriculum current, Page 2

Scott Library: rearrangement not renovation, Page 9

Reaching the peaks, Page 16

Jefferson scene, Page 20

Class notes, Page 28

Improving Interpersonal Perceptual Accuracy And Psychological Adjustment Through Brief Perception Therapy With A Substance Abuse Population, B. Gerald Hartman

Dissertations

This study's purpose was to determine if a type of cognitive therapy, Brief Perception Therapy, (Bullmer, 1980) could improve interpersonal perceptual accuracy and psychological adjustment in a substance abuse population. Thirty-five patients seeking inpatient treatment were randomly assigned to a treatment and a comparison group. Twenty-five patients completed the three week program, 13 in the treatment group and 12 in the comparison group. The treatment group received Group Brief Perception Therapy (GBPT) and the comparison group received Regular Group Therapy (RP). Therapists were experienced master's level psychologists and social workers trained in group treatment. GBPT groups used a programmed text, …

Robert Stuhlman Interview (1) Conducted On March 27 1984 About The Boonshoft School Of Medicine At Wright State University, Robert Stuhlman, James St. Peter

Boonshoft School of Medicine Oral History Project

This is the first of two interviews with Dr. Robert Stuhlman. Dr. Stuhlman is the Director of the Laboratory Animal Resources and is the Director of the Interdisciplinary Teaching Laboratories in the Wright State University School of Medicine. In this interview, Dr. Stuhlman discusses the initial organization and development of both programs and the problems encountered in the various moves made by Dr. Stuhlman and his staff.

Dr. Stuhlman also discusses the development of the staffs for the two sections within the School of Medicine and the philosophies under which they have grown during his tenure as director. Finally, Dr. …

Cushing's Disease Due To Pituitary Carcinoma, M. Saeed Zafar, R. C. Mellinger, J. L. Chason

Henry Ford Hospital Medical Journal

Criteria for the diagnosis of pituitary carcinoma are subject to controversy. Some authors do not accept the demonstration of cellular anaplasia alone as sufficient to establish the diagnosis but require evidence of metastatic disease in order to label a pituitary tumor as malignant. However, pituitary tumors can metastasize even in the absence of anaplasia. The present case of Cushing's disease and pituitary carcinoma had no clinical evidence of metastases when first reported. Partial surgical removal of the tumor followed by irradiation resulted in clinical remission of the Cushing's syndrome, but two years later progressive uncontrollable recurrence of the disease ended …

Family History As A Marker For Increased Risk Of Breast Cancer And Colon Cancer, Robert A. Norum

Henry Ford Hospital Medical Journal

Cancer of the breast and colon are well known to occur with high frequency in families with certain inherited cancer syndromes. These cancers also occur with increased frequency in families which do not have a recognizable genetic cancer syndrome. The fact of familial occurrence can be used to identify people with increased risk of cancer. In high-risk people methods for early detection can be developed which may reduce morbidity and mortality from these cancers, as has been done for certain inherited cancer syndromes.

External Beam Treatment Of Inoperable Non-Small Cell Carcinoma Of The Lung, H. Gunter Seydel

Henry Ford Hospital Medical Journal

External beam radiation therapy for unresectable non-small cell carcinoma of the lung has produced significant survival in patients with disease limited to one hemithorax. New approaches to improve the results of radiation treatment of these patients include interstitial implantation, the use of hypoxic cell sensitizers, biologic response modifiers, as well as changes in the technique of radiation therapy. This includes the use of modern computerized tomographic scanning technology for better definition of tumor volume as well as the use of two fractions per day in the treatment of non-small cell carcinoma of the lung. Initial results of these studies are …

The Spectrum Of B Cell Neoplasia, Michael J. Deegan

Henry Ford Hospital Medical Journal

Recent progress in our understanding of the immune system and the development of new techniques that permit the precise identification of lymphocytes have permitted a reexamination of lymphoid neoplasms. Most of the non-Hodgkin's lymphomas and lymphocytic leukemias have been characterized as T or B cell neoplasms and have been shown to possess features similar to those expressed by normal lymphoid cells at different stages of maturation. The clinical significance and therapeutic implications of these discoveries are now being explored. This paper presents a concise overview of the differentiation of human B lymphocytes, the surface and cytoplasmic markers that permit their …

The Current Controversies In Surgical Management Of Early Breast Cancer, Angelos A. Kambouris

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Social Work Intervention With The Aged: Toward A Change In The Institutionalized Thought Structure, Shimon S. Gottschalk, Michael Frumkin, Allan V. Kaufman

The Journal of Sociology & Social Welfare

The social problems associated with aging are viewed as derived from a series of socially defined meanings in the areas of: (1) power/authority,(2) responsibility, (3) productivity/work, (4) dependence/ independence,and (5) knowledge/rationality. A parallel series of alternative meanings is proposed which make possible the creation of alternative institutional forms which hold promise for making contemporary problems substantially obsolete. An era of post-professinalism is envisioned in which helping agents become political activists committed to social change on the cognitive, as well as the material level.

Empathy/Role Taking: A Theoretical Model For Feminist Therapy, Michele Wilson, Gayle Twilbeck Wykle

The Journal of Sociology & Social Welfare

Feminist therapy is directed not only at individual, but also at social change. Because of this dual aim of feminist therapy, the symbolic interactionist perspective, which describes individual initiative as a source of social change, is suggested as a theoretical orientation which can provide a useful model for feminist therapy. More specifically, the empathy/role-taking model for the clienttherapist relationship is outlined here.

What's Happening: February 22, 1984, Maine Medical Center

What's Happening

No abstract provided.

Psychosocial, Legal, And Ethical Dimensions Of Ultrasound Imaging In Pregnancy, Karen H. Rothenberg

Faculty Scholarship

No abstract provided.

Book Reviews Of Health Care Ethics By Benedict M. Ashley And Kevin D. O'Rourke -- Two Views On An Appology For The Value Of Human Life By David C. Thomasma -- Test-Tube Babies, A Guide To Moral Questions, Present Techniques, And Future Possibilities Edited By William Walters And Peter Slinger -- Choosing Well By Russell Shaw -- Parents' Guide To Adolescent Drug Addiction By Randy Engel, Catholic Physicians' Guild

The Linacre Quarterly

No abstract provided.

Interferon Gamma Blocks The Growth Of Toxoplasma Gondii In Human Fibroblasts By Inducing The Host Cells To Degrade Tryptophan., E. R. Pfefferkorn

Dartmouth Scholarship

Treatment of human fibroblasts with human recombinant gamma interferon blocked the growth of Toxoplasma gondii, an obligate intracellular protozoan parasite. Growth of the parasite was measured by a plaque assay 7 days after infection or by the incorporation of [3H]uracil 1 or 2 days after infection. The antitoxoplasma activity induced in the host cells by gamma interferon was strongly dependent upon the tryptophan concentration of the medium. Progressively higher minimal inhibitory concentrations of gamma interferon were observed as the tryptophan concentration in the culture medium was increased. Treatment with gamma interferon did not make the cells impermeable to tryptophan. The …

Novel Method Of Administering Β-Blockers And Novel Dosage Forms Containing Same, Anwar A. Hussain

Pharmaceutical Sciences Faculty Patents

The invention provides a novel method of administering selected known adrenergic β-receptor blocking agents, such as dichloroisoproterenol, pronethalol, sotalol and alprenolol, which are of use in the treatment of angina pectoris, arrhythmias, hypertension and other cardiac conditions, and migraine. The invention further provides novel dosage forms of those β-blockers which are adapted for nasal administration and which include solutions, suspensions, gels and ointments.

Warm Water Aquaculture Using Waste Heat And Water From Zero Discharge Power Plants In The Great Basin, Richard A. Heckmann, Robert N. Winget, Rex C. Infanger, Roger W. Mickelsen, John M. Hendersen

Great Basin Naturalist

Two series of experiments were completed to determine (a) toxicity of waste water from power plants on warm water fish and (b) multiple use of waste heat and water for aquatic animal and plant production. All three types of waste water from a typical coal-fired power plant are acceptable for growing catfish and tilapia following aeration. This growth was compared with fish raised in spring water. Closed, recirculating polyculture systems using evaporation pond water operated efficiently for plant (duckweed) and animal (fish and freshwater prawns) production. Duckweed is an excellent supplement for fish feed. Tilapia and freshwater prawns grew rapidly …

Samuel Kolmen Interview (2) Conducted On January 18, 1984 About The Boonshoft School Of Medicine At Wright State University, Samuel Kolmen, James St. Peter

Boonshoft School of Medicine Oral History Project

The second interview with Dr. Samuel N. Kolmen takes as its central theme the development of the bylaws for the School of Medicine, which Dr. Kolmen worked on as one of his first priorities upon arriving at Wright State University in 1975. Areas covered under the bylaws theme include: establishment of committee constituencies within School of Medicine committees; the political structure of the School of Medicine; the non-tenure system of the School of Medicine; policymaking in the School; the impact of the bylaws on the development of the School of Medicine and its integration into the university community.

Continuing the …

Samuel Kolmen Interview (1) Conducted On January 17, 1984 About The Boonshoft School Of Medicine At Wright State University, Samuel Kolmen, James St. Peter

Boonshoft School of Medicine Oral History Project

In the first of four interviews, Dr. Samuel N. Kolmen, first Chair of the Department of Physiology at the Wright State University School of Medicine, talks about his early career, academic background and his reasons for coming to Wright State University. He then goes on to discuss the state of development of the School of Medicine when he arrived at Wright State University in January, 1975 and his early tasks as department chairer [sic].

Dr. Kolmen discusses at length the development of the School of Medicine curriculum and the matrix departments in the School of Medicine, with emphasis on how …

Fluorescence Probes For The Study Of Acetylcholine Receptor Function, M. Martinez-Carrion, J.M. Gonzalez-Ros, J.R. Mattingly, J.A. Ferragut, M.C. Farach, D. Donnelly

Biochemistry and Molecular Biology Publications

Our group initiated the use of pyrene derivatives for functional and structural studies of the membrane-bound Acetylcholine Receptor (AcChR) system. Our studies have taken two approaches. We have recently used a hydrophobic derivative (pyrene-l-sulfonyl azide) that is able to bind covalently to regions of the AcChR molecule accessible from the membrane lipid (1) to monitor ligandinduced effects at those hydrophobic regions of the AcChR protein exposed to the membrane matrix (2). The structural effects induced by ligand binding are interpreted in relation to the AcChR "desensitization" process. We have also used a hydrophilic pyrene derivative (1,3,6,8-pyrene tetra sulfonate [PTSA]) to …

Mosquitoes As Vectors Of Disease In Minnesota, John W. Washburn

Journal of the Minnesota Academy of Science

Diseases due to mosquito-borne viruses occur every summer in Minnesota. The incidence of Western encephalitis and LaCrosse encephalitis is usually low, but outbreaks of Western encephalitis have occurred in the past. Evidence of Jamestown Canyon virus activity has been found in Minnesota. This virus may represent a newly-recognized cause of central nervous system disease and encephalitis. The epidemiology of the mosquito-borne encephalitis viruses found in Minnesota and the methods of disease surveillance and control are discussed.