Digital Commons Network^™

Case-Control Study Of Vitamin A Intake And Colorectal Cancer In Seventh-Day Adventists, John William Morgan

Loma Linda University Electronic Theses, Dissertations & Projects

Colorectal cancer is the second most common cause of cancer deaths in Americans; producing approximately 60,000 deaths in Americans each year. Studies of high and low risk populations have suggested a dietary etiology for colorectal cancer, although investigations of specific dietary factors have produced inconsistent results.

Population based studies of California Seventh-day Adventists demonstrate dietary variety regarding factors suspected as important in the etiology of colorectal cancer. These studies document a substantially reduced mortality and incidence from colorectal cancer in Seventh-day Adventists when compared to other California Populations. Although specific reasons for this difference remain obscure, the 'Unique lifestyle and …

A Comparison Of Liquid And Gel Etchants Determining Shear And Tensile Bond Strengths Of Four Orthodontic Adhesives, Gary M. Edgmon

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to compare liquid and gel etchants (37% phosphoric acid) by measuring tensile and shear bond strengths of four orthodontic adhesive systems.

Four orthodontic adhesives were tested on 287 extracted human teeth, 144 of which were etched with liquid and 143 with gel. The four adhesives tested were Concise-3M, Challenge-Ormco (new product), Unite-Unitek (no mix), and Fuji Glass-ionomer filling material or cement.

To eliminate the use of wire for bracket engagement during testing, two devices were designed and machined for direct attachment to the Instron testing machine: a rigid push rod for shear force and …

Identification Of Actinobacillus Spp Cell-Surface Antigens Using Monoclonal Antibodies, Kall S. Symons

Undergraduate Honors Capstone Projects

Though a senior project is required for graduation from U.S.U. with the Honors Program, there are no written guidelines describing the requirements of a U.S.U. Honors Senior Project. This proposal seeks to show how the present research project from the College of Agriculture should meet the intended project requirements of the Honors Director.

Developmental Expression Of Tyrosyl Kinase Activity In Human Serum., Ming-Fong Lin, Joan E. Bailey-Wilson, Robert C. Elston, Gail M. Clinton

Journal Articles: Biochemistry & Molecular Biology

Tyrosine protein kinases, in addition to their roles as viral transforming proteins and growth factor receptors, have been suggested to have specialized functions in tissue specific processes and in differentiation. High levels of soluble tyrosine kinases have been found in human serum and plasma. To determine if the level of tyrosine kinase activity is development tally expressed in human serum, we assayed sera from 214 individuals of different ages from newborns to 90 years. We found that serum tyrosine kinase levels are high in newborns and the levels closely parallel skeletal growth until late adolescence. The serum tyrosine kinase levels …

The Evaluation Of Factors Affecting Adherence To An Exercise Program Among College Students, Mark Robert Dean

Dissertations

Though investigative studies have identified the many benefits of aerobic exercise for both biological and behavioral health, only a small percentage of individuals maintain regular exercise. Team or group exercise programs report higher participation rates, but studies of individually prescribed exercise programs typically report problems of compliance and attrition. The purpose of the present study was to evaluate the effectiveness of various interventions--including the provision of course bonus points, cash lottery, and partner assignment--designed to increase exercise compliance among college students. Thirty-two student volunteers reporting "no current exercise" were randomly assigned to either the "partner" or the "individual" exercise group. …

The Effects Of Activity Group Structure On Cohesion, Engagement, And Affective Meanings In Acute-Care Psychiatric Patients, Hope L. Brucki

Masters Theses

Through activity analysis, occupational therapists identify various components of group structure and group processes for use in therapeutic activities. This study compared the effects of individual activity group structure (members engage in individual projects) and common activity group structure (members share a common project) in a sample of 38 acute-care psychiatric patients. Subjects were randomly assigned to one of eight theme-oriented poster-making groups, four for each experimental condition. Cohesion among group members was measured by the Group Environment Scale (GES), engagement was assessed by the Group Climate Questionnaire-Short Form (GCQ-S), and affective meanings were evaluated by Osgood's short-form semantic differential …

Compositions And Method Of Treatment For Sickle Cell Anemia, Donald F. Diedrich, Christopher L. Maynard

Pharmacology and Nutritional Sciences Faculty Patents

The invention provides a new composition and method for the treatment of sickle cell anemia. . . .

To see the remainder of this abstract, please download this patent.

Osteoporosis And Ert--The Jury Is Still Out, Mary E. Guinan, Karen Steinberg, Lambertina Freni-Titulaer

School of Public Health Faculty Research

Bone loss in women accelerates immediately after menopause, often leading to osteoporosis and an increased risk of bone fractures. In 1985,247,000 hip fractures occurred in people over 45 years of age. Among those who live to be 90, one-third of women and one-sixth of men will experience hip fractures. Six months after fracture, 25% of victims will not be able to carry out their usual activities, and 50% will need assistance to do so. Hip fractures are not only a serious cause of morbidity but they also increase the risk of mortality in older people. Because the proportion of the …

Update - May 1987, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Yoder addresses ethicists at LLU
-- Fletcher and Conolly debate active euthanasia
-- Theological Reflections Regarding AIDS

[ "No Code" Orders: Are They Moral? ]
-- Nurses and 'No Code' Orders
-- Let's Replace "Do Not Resuscitate" With "Care for the Dying"
-- What is a 'No Code' Order?

-- The Pandora's Box of Human Life - Society's Issue: Is Biology or Personality the Essential Ingredient? (Reprint)
-- Cowart, Campbell, Provonsha assess "Ethics at Life's End"

Quantitation Of Teratogenic Effects Of 5-Fluorouracil Administered To Mice In Vivo Or In Submerged Limb Culture, Theresa A. Sanders

Electronic Theses and Dissertations

This study demonstrates the use of submerged limb culture in teratologic testing. Pregnant mice were treated on day 11 of gestation (E11, plug date = E0) with 10, 20 or 40 mg of 5-fluorouracil (FU) per kg body weight. On E17, treated and untreated fetuses were examined for gross malformations and were fixed in 95% ethanol. Reduction of limb size and digital defects, including ectrodactyly (ED), syndactyly (SD), microdactyly and polydactyly were dose-dependent. In parallel studies, pregnant mice were treated on the morning of E11 and embryos were removed either 7h (E11) or 24h (E12) later for submerged limb culture. …

Adaptation Of Striped Bass To Sea Water Following Direct Transfer From Freshwater: Morphological, Biochemical, And Physiological Parameters, Judy A. King

Electronic Theses and Dissertations

There has been heightened interest in the biology of striped bass (Morone saxatilis) because of increased pollution in their native spawning grounds and because of their extensive use in landlocked sport fisheries. Their euryhalinity makes them an excellent species for osmoregulation studies. The objective of this research was to study the rate of adaptation of striped bass gills to sea water (3% salt) after direct transfer from freshwater using biochemical (ion transport enzyme levels), physiological (chloride efflux), and ultrastructural methods. Striped bass have specialized osmoregulatory cells located on the interlamellar and afferent surfaces of their gill filaments as shown by …

Ultrafiltration: Retentate-Permeate Partitioning Of Milk Constituents, Eric Douglas Bastian

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The effect of ultrafiltration, diafiltration, and preacidification of milk on the partition of specific milk components between retentate and permeate was studied. Percent retention (for any component Y) was determined as:

[1 - (%Y in soln. permeate/%Y in soln. retentate)] X 100 where %Y in soln. = [%Y / (%Y + %H₂O)]

Simultaneous samples of retentate and permeate were taken at several points during each process. Percent retention of total solids, fat, total protein, rennet clottable nitrogen, lactose, total calcium, ionic calcium, sodium, phosphorous, and riboflavin was determined at each sampling point. Percent retention of β-carotene, vitamin B …

The Effects Of Mothers' Attitudes And Willingness To Communicate Regarding Sexuality With Adolescent Daughters After Attending A 4-Hour Mother-Daughter Communication Workshop, Esther L. Dunlap

MSN Research Projects

The purpose of this quasi-experimental study was to determine the effect of a 4-hour mother/daughter sexuality workshop on the attitudes of mothers toward sexuality and their willingness to communicate sexuality to their adolescent daughters. The researcher sought to determine if there was a difference between mothers attending the mother/daughter workshop and mothers not attending the workshop. The hypotheses tested in this study were as follows: 1. When mothers who have participated in a 4-hour sexuality workshop are surveyed and the results are compared to a group of mothers not participating, there will be no significant difference in attitudes toward sexuality, …

Comparative Study Of Elongated Chromosomes In Sheep And Goats And A Proposed Standard, Stephen H. Mensher

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

A cell synchronization technique was used that consistently yielded numerous elongated chromosomes, which are necessary for producing high-resolution G-banding. The prometaphase stage of contraction was determined to have the greatest utility for detailed comparative analysis and, therefore, was used in the preparation of the proposed standard high-resolution karyotypes and idiogram.

A proposed standard high-resolution G-band karyotype of the domestic sheep and goat is presented, along with a high-resolution G-band idiogram of the goat. The karyotypes presented contain considerably more bands than contemporary karyotypes and provide much greater resolution for linear differentiation. The X chromosome of the sheep is acrocentric, rather …

Vital Signs, Spring 1987, Boonshoft School Of Medicine

Vital Signs

A thirty six page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Short Term Temporal And Spatial Variability Of Phytoplankton In The Elizabeth River, Robert L. O'Reilly

Biological Sciences Theses & Dissertations

This study was designed to evaluate short-term temporal and spatial components of phytoplankton variability within a tidal estuarine system, in reference to natural changes in the local environment.

Multiple water samples were collected weekly from October to December 1984 at 4 stations in different branches, or sections, of the Elizabeth River. Collection of chlorophyll~ data was structured to fit an analysis of variance, while the phytoplankton species and their environmental relationships were analyzed using multivariate techniques.

Lower chlorophyll a concentrations from 0.75 to 2.87 ug/1 were characteristic of the Main Stem and Southern Branch, while higher values of 1.27 …

Evaluating The Effect Of Family Stroke Education On The Anxiety Levels Of Families Of Stroke Patients, Keri Lynne Kuniyoshi

Loma Linda University Electronic Theses, Dissertations & Projects

[Abstract Not Included]

1987 Spring No. 13, School Of Medicine Office Of Alumni Affairs

Medicinews

LSU Medicinews Number 13 Spring 1987 was edited by Russell C. Klein, and published by the LSU School of Medicine Office of Alumni and Continuing Education Services.

This issue consists of 24 pages.

Jefferson Alumni Bulletin – Volume Xxxvi, Number 3, Spring 1987

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XXXVI, Number 3, Spring 1987

A call for reform, Page 2

An alumni potpourri, Page 7

Jefferson scene, Page 16

Class notes, Page 24

Noncariogenic Sweeteners: Sugar Substitutes For Caries Control, Curt S. Ayers, Richard A. Abrams

School of Dentistry Faculty Research and Publications

The evidence is clear that the incidence of dental caries is related to the frequency of eating sugar. The use of sugar substitutes is a suggested way of reducing sugar intake. A variety of noncariogenic sweeteners exists, but most have no practical value for caries control because of their technical or safety problems, taste, or cost. Urinary bladder tumorigenic effects have been reported in experimental animals treated with saccharin and cyclamates. Because of concerns for human safety, cyclamates were banned in the U.S., and saccharin use was permitted only by special legislation. The polyalcohols sorbitol and xylitol are important sugar …

Guilt, Ego Development, And Christian Faith, Dane Ver Merris

Dissertations

This research addressed the problem of whether a relationship exists between a particular level of ego development and guilt engendered by a rigid conscience based upon orthodox Christian beliefs. It was anticipated that forty-five graduate students at a conservative midwestern seminary who experienced higher levels of guilt and demonstrated a more rigid conscience/superego would score at the Conscientious stage of ego development measured by the Washington University Sentence Completion Test. Guilt and rigidity of conscience were measured by the Sixteen Personality Factor Questionnaire.

Object relations theories of the origins of guilt were examined along with the relationship between object relations …

An Otopathological Assessment Of Dogs Exposed To Excessive Dietary Fluoride And/Or Suspected Water Borne Toxins, Barbara Ann Hannah

Masters Theses

In 1970, a once very productive Allegan, Michigan dog kennel began experiencing a rash o£ unexplained perinatal deaths and reproductive anomalies in Shetland pups. Anomalies including cleft palate and lip, kinked tails, twisted feet and convulsions immediately before death plagued the neonates. The adult dogs were reported to have tooth mottling, exostoses and auditory and vestibular problems.

Because the dogs had been on high fluoride diets and because the kennel well water was suspected of harboring toxins, a group of 20 Shetland dogs was used to try to find if there was any correlation between the reproductive problems and the …

Pre-Natal Learning Needs Perceptions Of Expectant Parents And Childhood Educators, Cynthia Divens Sweeney

Ellmer School of Nursing Theses & Dissertations

The purpose of this study was to examine the differences between the unique learning needs of expectant parents and those perceived by childbirth educators. A purposive sample of 40 expectant parents and ten childbirth educators completed the Expectant Parents Learning Needs Tool (EPLNT) and a demographic inventory developed by the researcher. Subjects were classified into five groups based on their status as first-time fathers, repeat fathers, first-time mothers, repeat mothers, and childbirth educators. Data were analyzed using t-tests for independent samples and an ANOVA for group differences. The results showed significant differences in the learning needs between the expectant parents …

The Clinicians' Guide To Creutzfeldt-Jakob Disease, Thomas H. Swanson

Henry Ford Hospital Medical Journal

Creutzfeldt-Jakob disease, a transmissible, rapidly progressive dementia of unknown etiology, mimics Alzheimer's disease, presents in middle life, and affects many central nervous system structures. The disease progresses in three distinct stages, culminating in death. Its occurrence is sporadic and its distribution worldwide. Pathological changes are varied, but spongy degeneration of the neuropil is classic. Research on scrapie, the animal model of Creutzfeldt-Jakob disease, has demonstrated that this unconventional, slow disease is transmitted via a small (less than 50,000 mW) particle, which is composed principally of protein. How this infectious particle, variably named prion, virino, or slow virus, invokes disease or …

Stress Of The Caregiver: Effective Management Of Dementia Patients In Hospital And Community Settings, Ruth E. Dunkle, Michael Nevin

The Journal of Sociology & Social Welfare

This study explores the management problems among elders with dementia and their medical and family caregivers. Twenty-five patients were interviewed as well as professional health care personnel and a family member. Findings indicated that professional assessment facilitates home caregiving but has little bearing on successful coping by the caregiver. Variability of coping relates to the strategy employed.

Molecular Cloning Of Human Synovial Cell Collagenase And Selection Of A Single Gene From Genomic Dna., Constance E. Brinckerhoff, Peggy L. Ruby, Scott D. Austin, M Elizabeth Fini, Hillary D. White

Dartmouth Scholarship

We used a subclone of a rabbit genomic clone for collagenase that cross-hybridizes with human synovial cell messenger RNA (mRNA) to identify a human collagenase complementary DNA (cDNA) clone. The human cDNA clone is 2.1 kilobases (kb) and selects a mRNA transcript of approximately the same size from primary cultures of rheumatoid synovial cells that produce collagenase, but no mRNA is selected from control (nonproducing) synovial fibroblasts. Restriction enzyme analysis and DNA sequence data indicate that our cDNA clone is full length and that it is identical to that recently described for human skin fibroblast collagenase. The cDNA clone identified …

Habitat Utilization By Harpacticoid Copepods: A Morphometric Approach, Susan S. Bell, Keith Walters, Margaret O. Hall

Integrative Biology Faculty and Staff Publications

Examination of harpacticoid copepod morphology was conducted to determine whether morphological resemblance provides a reasonable index of habltat utilization and movement. Discriminant analysis was used to explore the relationship between body form and habitat utilization for copepod species collected from 3 subhabitats within seagrass beds in Tampa Bay, Florida. To examine the accuracy of our procedure the discriminant function derived for Tarnpa Bay copepods was applied to copepods collected in worldwide studies. Three morphological characteristics - ratio of the length of Pereopod 1 first endopod segment to the remaining endopod segments, area of the cephalosome, and length of the first …

The Relationship Of Temperament To Tolerance Of Cold And Heat: Beyond “Cold Hands-Warm Heart”, Richard A. Dienstbier, Robert L. Laguardia, Noreen S. Wilcox

Department of Psychology: Faculty Publications

Thermal regulation and peripheral arousal in episodes of emotion are dependent upon similar autonomic and hormonal processes. Thermal-tolerance measure were developed and validated in order to indirectly assess adrenergic (cold tolerance) and cholinergic (heat tolerance) responsivity. We hypothesized that cold tolerance would correlate with reduced emotionality (largely fear and anxiety) and depression, and with increased stimulus seeking and dispositions toward activity; those hypotheses were confirmed. Tentatively advanced hypotheses that heat tolerance would correlate with reduced depression and emotional states were not confirmed, but heat tolerance was positively associated with activity and (weakly) with some of the same dimensions of temperament …

Finding Aid For Jax Oral History, Susan Mehrtens

Oral History Collection

No abstract provided.

Biotechnology In The Conquest Of Infectious Diseases, Ashley T. Haase

Journal of the Minnesota Academy of Science

No abstract provided.