Digital Commons Network^™

Assessing The Pragmatic Skills Of Adolescents With And Without Learning Disabilities On A Dramatization Task, Amy L. Juergens

Masters Theses

This study was designed to compare the pragmatic skills of adolescents with and without learning disabilities as measured by a dramatization task. Seventeen high school students with learning disabilities and 17 normal-achieving high school students participated in this study. Twenty scenes were presented verbally to the participants who were instructed to act out the part of a character in each scene, making up the dialogue to fit the scene. The responses were scored for their pragmatic appropriateness and linguistic quality. Task reliability and validity analyses indicated that the dramatization task was an effective measure of key aspects of pragmatic skills. …

Distribution Of Endosomal, Lysosomal And Mhc Markers In A Monocytic Cell Line Infected With Chlamydia Psittaci, David M. Ojcius, Raymond Hellio, Alice Dautry-Varsat

All Dugoni School of Dentistry Faculty Articles

The intracellular fate of Chlamydia psittaci during infection of a monocytic cell line, THP1, was characterized. Cytochalasin D inhibited phagocytosis of latex beads but had no effect on infection by C. psittaci, and vacuoles expressed the transferrin receptor, suggesting accessibility to the endocytic pathway. Early Chlamydia-containing vacuoles expressed major histocompatibility complex (MHC) class I molecules, and most vacuoles fused with host cell lysosomes, since they expressed LAMP-1 and had acidic pHs. In cells prestimulated with gamma interferon, vacuoles also expressed MHC class II molecules, suggesting that the monocytes might effectively process Chlamydia-derived antigens for presentation by MHC class I and …

Jefferson Alumni Bulletin – Volume Xlvi, Number 3, June 1997

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLVI, Number 3, June 1997

Dermatology and Cutaneous Biology, Page 4

Mutations in Cornea-Specific Proteins Are Cause of Fragile Eye Disease, Page 8

Albert Einstein Healthcare Network Becomes a Founding Member of the Jefferson Health System, Page 9

Innovative New Journal has Jefferson Roots, Page 11

Students Publish Pharmacology Study Guide, Page 12

JeffLINE Alumni Connection Offers Lifelong Learning, Page 23

Molecular And Cellular Biology Of Prostate Cancer, El-Nasir Lalani, Marc Elie Laniado, Paul David Abel

Department of Pathology and Laboratory Medicine

Prostate cancer is an enigmatic disease. Although prostatic-intraepithelial neoplasia appears as early as the third decade and as many as 80% of 80 year old men have epithelial cells in their prostate that fit the morphological criteria for cancer, only about 10% of men will ever have the clinical disease and less than 3% will die from it. There have been no significant proven interventions which have altered the natural history of the disease since hormone down regulation was introduced in the 1940s and new research has been poorly supported. There is however an urgent need to develop new criteria …

1997 - The Second Annual Symposium Of Student Scholars

Symposium of Student Scholars Program Books

The full program book from the Second Annual Symposium of Student Scholars, held on May 23rd, 1997. Includes abstracts from the presentations and posters.

Density, Distribution, And Habitat Of Flammulated Owls In Idaho, Craig Groves, Terry Frederick, Glenn Frederick, Eric Atkinson, Melonie Atkinson, Jay Shepherd, Gregg Servheen

Great Basin Naturalist

From 1990 to 1992 we surveyed for Flammulated Owls (Otus flammeolus) in 3 areas in Idaho: Salmon National Forest (SNF), Payette National Forest and adjacent Hells Canyon National Recreation Area (PNF-HCNRA), and Nez Perce National Forest (NPNF). We also collected and summarized information on all historic and modern records of Flammulated Owls in Idaho. Flammulated Owls were detected on 65% of 68 routes (2–16 km in length) surveyed at densities ranging from 0.04 to 1.25 singing males/40 ha. Owls were detected on survey routes as early as 10 May and as late as 23 July. Mean percent canopy …

Diplostomiasis In Native And Introduced Fishes From Yellowstone Lake, Wyoming, Victor H. Inchausty, Michael Foutz, Richard A. Heckmann, Claudete Ruas, Paulo Ruas

Great Basin Naturalist

Totals of 101 native Yellowstone cutthroat (Oncorhynchus clarki bouvieri), 27 introduced lake trout (Salvelinus namaycush), and 40 introduced longnose sucker (Catostomus catostomus) from Yellowstone Lake, Wyoming, USA, were examined for eye flukes. Metacercariae of the trematode fluke Diplostomum were in vitreous humor and/or lens of 94% of Yellowstone cutthroat trout, 92% of lake trout, and 78% of longnose sucker. Longnose sucker had 7% prevalence of infection in both lens and vitreous humor of metacercariae, while Yellowstone cutthroat trout had 3% and lake trout 8%. Diplostomum spathaceum was in lens tissue of 5% of infected …

Dentalgram - Vol. 11, No. 05, Loma Linda University School Of Dentistry

Dentalgram

In this issue:

• Accolades to LLUSD Students
• Dr. Boyne Publishes Book
• Clinic with a Heart
• Biocompatibility Specialist Joins LLUSD
• Dr. Crawford Visits Africa
• Class of 2000 Statistics
• Millennial Class Named
• Volunteerism
• Employee Appreciation
• CPR Renewals
• Birthdays

Genetic Markers And Duodenal Ulcer, Anjum Shahid, Sarwar J. Zuberi, Anwar Ali Siddiqui, Muhamined A. Waqar Muhamined A. Waqar Muhamined A. Waqar

Department of Biological & Biomedical Sciences

Serum pepsinogen, ui-antitrypsin (ui-AT) and blood groups were studied as genetic markets in 32 patients with endoscopically proven duodenal ulcer and 44 control subjects with no family history of ulcer disease. Serum pepsinogen was detennined by the modified method of Edward et al7, a1-AT by single radial hnmunodiffusion8 (RID) and phenotyping was carried out by isoelectric focusing (IEF)9. Duodenal ulcer patients with hyper- pepsinogenemia (28%) and low serum ui-AT (35%) had a dominant blood group 0, lower mean age, an early onset of disease, a higher frequency of gastrointestinal (CI) bleeding and ulcer perforation. These parameters were found considerably different …

Dna-Protein Cross-Linking By Pyrrolizidine Alkaloids, Gail L. Drew

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Pyrrolizidine alkaloids (PAs) are natural plant compounds found in hundreds of plant species worldwide and are reported to have cytotoxic, carcinogenic, antimitotic, and genotoxic activity. PAs are metabolized by the cytochrome P450 (CYP) system to the pyrrole or the N-oxide form. The pyrroles are bifunctional electrophilic alkylators that bind cellular nucleophiles such as DNA and proteins and sirupt normal cell processes, including DNA replication and gene transcription and can cause megalocytosis. The pyrroles dehydrosenecionine (DHSN) and dehydromonocrotaline (DHMO) are among the most potent PA cross-linkers and inducers of megalocytosis. DHSN and DHMO-induced cross-links in cultured normal (MDBK) and neoplastic (MCF7) …

Fetal Alcohol Syndrome: Information And Intervention Strategies For School, Home, And Therapeutical Settings, Mindy Dawn Anderson

Undergraduate Honors Capstone Projects

I was introduced into the world of Fetal Alcohol Syndrome winter quarter, 1996. My goals for that year included researching this topic in order to understand what it was physically, behaviorally, and on a cognitive level. My assignment involved writing a research paper around those characteristics, along with the development of their speech and language, presenting my findings to my classmates, and competing at the USU Scholar's Day competition in May of 1996. I received 2nd place at this competition. During the summer of that year, I researched FAS more to receive the needed resources to compile an annotated bibliography …

The Process Of Ending Domestic Violence Among Latinas: Aguantando No Mas, Nancy A. Coffin-Romig Dnsc, Msn, Rn

Dissertations

The purpose of this study was to explore the sociocultural factors which play a role in the process of ending an abusive relationship among Latinas. Dimensional analysis was the method employed for the development of a grounded theory. Aguantando or enduring emerged from this study as pivotal in gaining an understanding of the process of ending an abusive relationship for Latinas. Participants indicated that personal and religious beliefs, the importance of family, and the needs of their children were reasons for aguantando or enduring the abuse. The decision to no longer aguantar, or endure, occurred through a series of encounters …

The Work Of Living With Hiv: A Study Of Binational Groups, Christina Joy Dnsc

Dissertations

The purpose of this investigation was to study the experience of individuals who live with and manage HIV infection and AIDS. The context of living with HIV/AIDS, the prevailing conditions, the actions/strategies used, and the consequences of the actions were considered using grounded theory methodology and dimensional analysis. A purposeful sample of 21 individuals HIV positive or diagnosed with AIDS from San Diego, California and Tijuana, Mexico were interviewed using semi-structured questions. Data were analyzed using open and axial coding, the constant comparative method, and dimensional analysis. The work of living with HIV emerged as the central dimension within the …

Living With Changing Health: Perimenopause Among Chinese Women In Taiwan, Lee-Ing Tsao Dnsc, Mnsc, Rn

Dissertations

The purpose of this qualitative study was to generate theory about women's perimenopausal life experiences. Thirty-five Taiwanese women aged 40 to 59 who perceived themselves as perimenopausal and who were not using hormone therapy were interviewed. Data were generated from interviews which were conducted in Mandarin. Living with Changing Health was the core category for describing and guiding the process of perimenopause. During this process, Awareness was identified as the antecedent condition. Once the woman became aware, she would begin the process of living with her changing health. This process would be marked by action and interaction among the categories …

Characterization Of Angiotensin Ii Receptor Subtypes In The Brain, David L. Saylor

Electronic Theses and Dissertations

The present studies explore binding, distribution, and function of angiotensin II (AII) receptors (AT$\sb1$ and AT$\sb2)$ in the brain. The discovery that sulfhydryl reducing agents masked some but not all AII receptors in the brain prompts an evaluation of commonly used binding assay buffer constituents. EDTA enhances binding (40%) at both AT$\sb1$ and AT$\sb2$ nuclei, while bacitracin did not alter binding at either receptor subtype. Phenanthroline and BSA differentially altered binding at AT1 (220% of control) and AT$\sb2$ (118% of control) receptors. The results indicate that phenanthroline and BSA would be poor buffer constituents for studies comparing binding at AT$\sb1$ …

The Experiences Of Taiwanese Women Caregiving For Parents-In-Law, Shu-Yuan Chao Dnsc

Dissertations

Using grounded theory, a semi-structured in-depth interview was conducted to explore the experiences of Taiwanese women who were caregivers for their parents-in-law. Thirty-one Taiwanese women aged 23 to 58 participated in this study. Just Doing was identified as the core category to indicate the caregivers' striving process once they committed to their in-laws' care. Recognizing Duty, Experiencing Trials, and Responding to Caregiving were subcategories and reflected how a caregiver perceived her role, how she was affected by caregiving tasks, and what responses she had to the caregiving situation. The findings also suggested that caregiving behaviors were influenced by cultural expectations …

Determinants Of Health-Promoting Lifestyle Among Nurses In Taiwan, Chou Chuan-Chiang Yao Dnsc, Ms, Rn

Dissertations

This two-phase study was undertaken to: (1) determine the relationships of self-efficacy, perceived health status, perceived social support, age, marital status, education, work shift, work setting, and years employed as a registered nurse (RN) to the practice of a health-promoting lifestyle; (2) determine the combination of predictor variables explaining the variance in the practice of a health-promoting lifestyle; and (3) investigate other personal and environmental cues and characteristics related to health-promoting lifestyles among nurses (N = 218) in Taiwan. Findings of the quantitative approach in Phase One indicated that a health-promoting lifestyle was significantly related to self-efficacy, perceived health status, …

Hallucinations, Peter J. Whitehouse, Marian B. Patterson, Milton E. Strauss, David S. Geldmacher, James L. Mack, Grover C. Gilmore, Elizabeth Koss

Faculty Scholarship

No abstract provided.

Fetal Alcohol Syndrome: Information And Intervention Strategies For School, Home, And Therapeutical Settings, Mindy Dawn Anderson

Undergraduate Honors Capstone Projects

I was introduced into the world of Fetal Alcohol Syndrome winter quarter, 1996. My goals for that year included researching this topic in order to understand what it was physically, behaviorally, and on a cognitive level. My assignment involved writing a research paper around those characteristics, along with the development of their speech and language, presenting my findings to my classmates, and competing at the USU Scholar's Day competition in May of 1996. I received 2nd place at this competition. During the summer of that year, I researched FAS more to receive the needed resources to compile an annotated bibliography …

Aflatoxin B1 Metabolism In Mammalian Pulmonary Tissue, J. Michael Eichelberger

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Aflatoxin B₁ (AFB₁) is a potent dietary hepatocarcinogen and may be a lung carcinogen when inhaled. To study the relative ability of lung and liver to metabolize AFB₁, a susceptible (Swiss-Webster rat) and resistant species (Syrian golden hamster) were pretreated with inducing agents in order to identify specific AFB₁ metabolizing enzymes in each tissue.

Analysis of AFB₁-exo-epoxide (AFBO) formation, O-dealkynation assays, and protein immunoblots demonstrated that cytochrome P450 (CYP) 1A proteins were overexpressed in both the lung and liver of hamsters pretreated with 3-methylchyolanthrene (3-MC). Only CYP1A1 was expressed in the lung …

Devolpment Of A Scale To Assess Home Health Care Aides' Ability To Recognize Depression In Older Adults, Tina M. Nerney

Community & Environmental Health Theses & Dissertations

Depression afflicts 20% to 40% of people 65 and older. Depression in older adults is frequent and chronic. The challenge of a hospital stay and the knowledge of having a long term disability may increase the risk for a depressive episode. In today's health care environment older adults are being released from hospitals after a short length of stay and are frequently dependent on home health services for assistance with activities of daily living. Home health care aides are given the responsibility of providing these services to the older adult in the home environment and need to be aware of …

The Developmental Abilities Of Neonatal Intensive Care Unit Graduates, Cynthia A. Gonzalez

Theses and Dissertations - UTB/UTPA

Bayley Mental Psychomotor Developmental Indices Scores of 61 Neonatal Intensive Care Unit Graduates were examined to investigate whether a predicted early developmental lag would occur followed by an increase or "catch-up" over time. Results indicated that no significant changes occurred over time; however, mental (Bayley MDI) scores were lower than motor (Bayley PDI) scores particularly at the 4- and 22-month test age. Gross motor, fine motor, social, cognitive, and language development was also investigated to see whether expected differences among these domains occurred over time. Results indicated that gross motor scores were greater than all other domains. Ethnicity, birth weight, …

Spin Trapping Pharmaceutical Compositions And Methods For Use Thereof, John M. Carney, Robert A. Floyd

Pharmacology and Nutritional Sciences Faculty Patents

Spin trapping compositions in general have now been discovered to be effective in treating a variety of disorders, including disorders such as those arising from ischemia, infection, inflammation, exposure to radiation or cytotoxic compounds, not just of the central and peripheral nervous systems but of peripheral organ disease having a wide variety of etiologies. In the preferred embodiment, the compositions for treating tissue damage from ischemia contain PBN, or active derivatives thereof, in a suitable pharmaceutical carrier for intravenous, oral, topical, or nasal/pulmonary administration. Many different disorders can be treated using these compounds, including diseases or disorders of the central …

Alterations In Human B Cell Calcium Homeostasis By Polycyclic Aromatic Hydrocarbons: Possible Associations With Cytochrome P450 Metabolism And Increased Tyrosine Phosphorylation, Barbara J. Mounho

Pharmaceutical Sciences ETDs

Polycyclic aromatic hydrocarbons (PAHs), are known immunotoxicants in animals, and are suspect toxins to the human immune system. The mechanism(s), however, by which PAHs exert immunosuppression have not been fully elucidated. Previous studies conducted in our laboratory have shown that PAHs, such as 7,12-dimethylbenz(a)- anthracene (DMB A) and benzo(a)pyrene (BaP) may exert their immunotoxic effects by altering intracellular calcium (Ca2+) homeostasis in lymphocytes. Intracellular Ca2+ is an important second messenger in the immune response, and the mobilization of Ca2+ is critical in the transduction of intracellular signals from the plasma membrane to the nucleus. The overall objective of this project …

Vital Signs, Spring 1997, Boonshoft School Of Medicine

Vital Signs

A twenty four page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Immunophenotypic Analysis Of Non-Hodgkin's Lymphoma, Suhail Muzaffar, Shahid Pervez, Farrukh Aijaz, Syed Abdul Aziz, Sheema H. Hasan

Department of Pathology and Laboratory Medicine

One hundred and three cases of Non-Hodgkin’s lymphoma were evaluated immunohistochemically using a panel of monoclonal antibodies which includes leucocyte common antigen (LCA), CD45R (Pan-B marker), L-26 (CD 20-Pan-B marker) and UCHL-1 (Pan-T marker). Of the total 63 cases (61.17%) showed a B-cell phenotype while 40(38.83%) were of T-cell origin. Most B-cell neoplasms belonged to intermediate (79.36%) or high grade (15.87%) according to the international Working Formulation (WF). Most T- cell lymphomas were of either intermediate (52.5%) or high grade (32.5%) neoplasms. Some T-cell neoplasms presented as specific clinicopathological entities like lymphomatoid granulomatosis (2 cases), mycosis fungoides (1 case) and …

A Correlational Study Of Infertility And Marital Satisfaction, Charles H. Mccomb Jr.

Theses

This study examined the correlation between infertility and marital satisfaction. Thirty-six subject participated in the study. The participants were recruited from a support group. Other recruits came from friends. The survey was sent, completed, and returned by mail as to retain anonymity. The subjects came from St. Louis, MO. Most of the individuals in the study were white, Non-Hispanic, middle class, and college graduates. Each individual completed a demographic questionnaire and the Kansas Marital Satisfaction Scale. The compiled results found that there is a significant relationship between gender and marital satisfaction in a group of individuals with fertility problems. Another …

The Influence Of Low Dietary Fat Intake On Incidence And Severity Of Migraine Headache, Zuzana Bic

Loma Linda University Electronic Theses, Dissertations & Projects

Migraine headaches are a common and debilitating syndrome causing untold suffering and loss of productivity. A review of the literature indicates that there are two primary factors involved in triggering these headaches: high levels of blood lipids and high levels of free fatty acids. Under these conditions platelet aggregability is increased, which is associated with decreases in serotonin and heightened prostaglandins levels. These conditions may produce vasodilation, the most immediate precursor to migraine headache. A high fat diet is one factor that may directly affect this process. This study was undertaken to evaluate the impact of dietary fat intake on …

Dissection Of A Circadian Oscillation Into Discrete Domains, Martha W. Merrow, Norman Y. Garceau, Jay C. Dunlap

Dartmouth Scholarship

The circadian oscillator in Neurospora is a negative feedback loop involving as principal players the products of the frequency (frq) locus. frq encodes multiple forms of its protein product FRQ, which act to depress the amounts of frq transcript. In this scheme there are two discrete and separable steps to the circadian cycle, negative feedback itself (repression) in which FRQ acts to decrease the levels of its own transcript, and recovery from repression (derepression) in which frq transcript levels return to peak amounts. By introducing an exogenously regulatable frq transgene into a frq loss-of-function strain (frq^{9 …}

Paying For Suffering: The Problem Of Human Experimentation, Larry I. Palmer

Faculty Publications

No abstract provided.