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Adverse Impact Of Predisposition Testing On Major Life Activities: Lessons From Brca 1/2testing, Katherine A. Schneider

Journal of Health Care Law and Policy

No abstract provided.

Intimate Partner Violence And Cervical Neoplasia, Ann L. Coker, Maureen Sanderson, Mary Kay Fadden, Lucia Pirisi

CRVAW Faculty Journal Articles

Intimate partner violence (IPV) is associated with a range of adverse physical health outcomes, including chronic and infectious diseases. An emerging literature suggests that partner violence and specifically sexual violence may be associated with an increased risk of cervical neoplasia. To assess the risk of preinvasive and invasive cervical cancer in a cross-sectional study of women screened for IPV by type, frequency and duration, 1152 women ages 18–65 were recruited from family practice clinics in 1997–1998. They were screened for IPV during a brief in-clinic interview, and health history and current status were assessed in a follow-up interview. Of 1152 …

Predictors Of Academic Success In The University Of North Dakota Master Of Physical Therapy Program, Chantel J. Helling

Physical Therapy Scholarly Projects

The purpose of this study is to evaluate variables/criteria available for the admissions process and identify which prove to be the strongest predictors of academic and clinical success in the University of North Dakota Professional Physical Therapy Program. It is also intended to review the current admission processes being utilized and look for new indicators of success that may be beneficial to this curriculum.

The subjects utilized in this study are physical therapy students (excluding the Western Interstate Commission of Higher Education enrolled students) admitted from the years of 1991 - 1995. Data were first extracted from student files by …

Physical Activity: Essential Component In Primary And Secondary Curricula For Lifelong Health, Maril Mccord

Physical Therapy Scholarly Projects

Chronic disease, preventable illness and injury, and growing trends of sedentary behaviors have currently been associated with the American population. It is estimated that 70% of all deaths in America are attributable to chronic disease of a preventable nature. Childhood disease has declined only to be replaced by new waves of social, environmental, and behavioral factors which manifest as health risks. At least 68 million Americans suffer from some form of heart disease while nearly 60% of adults lead sedentary lifestyles. The challenge in the nation is to counter these trends by implementation of policy and programs for healthier habits …

The Effects Of Electromagnetism For The Treatment Of Multiple Sclerosis, Michele A. Morse

Physical Therapy Scholarly Projects

Electromagnetic treatment is one of the highest utilized nontraditional therapeutic methods in the medical field. Scientific research has proposed that people experience improvement in the symptoms of multiple sclerosis (MS) from such treatment. This independent study is a literature review that probes into the proclaimed benefits that a low frequency electromagnetic field posses on the biological system. In order to support or negate these claims, literature and studies explaining how and why this concept is feasible is researched and presented. The review focuses on the effects of the low frequency external electromagnetic field at the cellular level and on central …

The Lymphatic System, Lymphedema, And A Discussion Of Methods For Treatment: A Review Of The Literature, Lisa Schneider

Physical Therapy Scholarly Projects

The condition of lymphedema has a significant impact of the quality of life of the person affected. Few patients are educated about the possibility of developing lymphedema and methods for prevention of lymphedema following surgical removal of lymph nodes or radiation therapy. Also, most physical therapists have received minimal or inadequate training in the area of lymphedema treatment. Hence, physical therapists may actually damage a patient's lymphatic system by using inadequate techniques.

The purpose of this literature review is to examine the lymphatic system, discuss the condition of lymphedema, and review various methods for prevention and treatment of lymphedema in …

Predictors Of Academic Success In The University Of North Dakota Master Of Physical Therapy Program, Sherry Sisneros

Physical Therapy Scholarly Projects

Due to the fact that the number of positions available in the University of North Dakota's Physical Therapy program is few yet the number of qualified applicants is many, the admissions committee has the responsibility to be selective in their process to ensure the most qualified students are admitted. In order to determine the most qualified students, one needs to determine the possible variables that predict not only academic, but clinical success as well.

Data was gathered from 145 students who attended the UND-PT program with admit years of1991-1995. Traditional descriptive and analytical statistics were utilized to describe applicants, outcomes, …

A Comparison Study Of Depression In The Elderly: Traveling South Versus Staying In The Midwest For The Winter, Sandra M. Zieffler

Physical Therapy Scholarly Projects

Depression is the primary mental health disorder in the elderly (people 65 years old and older). As the elderly are the fastest growing segment of the population in the United States, an increasing number of elders will be affected by this illness. The purpose of this study was to compare depression in the elderly between those who stay in the Midwest (Minnesota or North Dakota) year-round and those who travel south for all or part of the winter. A four-page self-administered questionnaire was distributed to 227 people thought to be at least 65 years old. The questionnaire consisted of background …

Role Of KAtp Channels In Reduced Antinociceptive Effect Of Morphine In Streptozotocin-Induced Diabetic Mice, Vivek Sood, Ajay Sharma, Manjeet Singh

Pharmacy Faculty Articles and Research

The nociceptive effect was measured using withdrawal latency in tail flick test in mice rendered diabetic by administering streptozotocin (200 mg/kg, i.p.). The antinociceptive effect of morphine (4 and 8 mg/kg, s.c.) and cromakalim, a KATP channel opener, (0.3, 1 and 2 micrograms, i.c.v.) was significantly reduced in diabetic mice. Moreover, co-administration of cromakalim(0.3 microgram) did not alter the reduced antinociceptive effect of morphine(4 mg/kg) in diabetic mice. Spleenectomy in diabetic mice restored the decrease in antinociceptive effect of morphine and cromakalim. Multiple dose treatment with insulin to maintain euglycaemia for 3 days in diabetic mice prevented the decrease in …

Identification Of The Transactivation Domain Of The Transcription Factor Sox-2 And An Associated Co-Activator, Tamara K. Nowling, Lance R. Johnson, Matthew S. Wiebe, Angie Rizzino

Nebraska Center for Virology: Faculty Publications

The importance of interactions between Sox and POU transcription factors in the regulation of gene expression is becoming increasingly apparent. Recently, many examples of the involvement of Sox-POU partnerships in transcription have been discovered, including a partnership between Sox-2 and Oct-3. Little is known about the mechanisms by which these factors modulate transcription. To better understand the molecular interactions involved, we mapped the location of the transactivation do-main of Sox-2. This was done in the context of its interaction with Oct-3, as well as its ability to transactivate as a fusion protein linked to the DNA-binding domain of Gal4. Both …

Quantitative Image Analysis Of Simian Immunodeficiency Virus Replication In Macrophages Coinfected With Mycobacterium Avium Complex, Qingsheng Li, Keith G. Mansfield, Andrew Lackner, Ashley T. Haase

Qingsheng Li Publications

Mycobacterium avium is the most frequent cause of disseminated bacterial infection in patients with human immunodeficiency virus type 1 infection and in rhesus macaques with simian immunodeficiency virus (SIV) infection. This animal model of AIDS was used to test the hypothesis that this frequent association is the result of reciprocal enhancement of replication of both microorganisms. The replication of M. avium and SIV was analyzed in lymphatic tissues obtained from rhesus macaques experimentally inoculated with SIVmac who developed or remained free of overt M. avium infection. In situ hybridization, quantitative image analysis, and staining of M. avium and of macrophages …

Self-Mutilation : Using Pain To Cope, Wendy S. Cook

Graduate Research Papers

Self-mutilation is a serious mental and physical health problem that is often under-reported and misdiagnosed. The mutilation is a reaction to negative internal feelings, such as despair, anxiety, anger, or cognitive constriction. The goal of the self-mutilation is relief from emotional pain by using physical pain. The self-mutilator has low self-esteem, bouts of depression, difficulty forming intimate relationships, and usually suffered some type of trauma such as physical or sexual abuse. Pharmacological treatment for the self-mutilator has been experimental but has not been well researched. However, research seemed to indicate that individual and group therapy, specifically cognitive-behavioral therapy, is helpful …

Men As Supportive Partners In Reproductive Health: Moving From Rhetoric To Reality, Saraswati Raju, Ann Leonard

Reproductive Health

This book builds on presentations of the Workshop on Men as Supportive Partners in Reproductive and Sexual Health held in Kathmandu, Nepal, in 1998. By analyzing the experiences of nongovernmental organizations across India, this publication reviews important concerns that should inform the discourse on male partnership. The previous views of reaching men as contraceptive users and removing them as impediments to women’s efforts to control fertility are too limited. The argument is not whether men and women should use family planning, but rather the extent to which men can become supportive of women’s reproductive and sexual rights and actively take …

Sexual And Reproductive Health And Health Sector Reform In Latin America And The Caribbean: Challenges And Opportunities, Ana Langer, Gustavo Nigenda, Sandra G. Garcia, Rosario Valdez, Emanuel Orozco, Jennifer Catino

Reproductive Health

Most countries in Latin America and the Caribbean (LAC) are at varying stages of a reform process to improve the response capacity of health systems by upgrading the effectiveness and sustainability of programs and services. Changes promoted by the reform focus on priority health needs and underprivileged society groups. Some problems, such as sexual and reproductive health (SRH), can be tackled with cost-effective technologies. Reform projects offer a unique opportunity to reconsider policies, programs, and services aimed at facing the issues encompassed in the term SRH. Nonetheless, the formulation of a strategy and the identification of concrete measures represent a …

Identification Of Violence In The Home - Pediatric And Parental Reports, Bonnie D. Kerker, Sarah Mccue Horwitz, John M. Leventhal, Stacey Plichta, Phillip J. Leaf

Community & Environmental Health Faculty Publications

Objectives: To compare the rates of domestic violence reported by mothers with those identified by physicians, to compare the rates of harsh discipline practices reported by mothers with the rates of abuse identified by physicians, and to examine the relationship between reported domestic violence and harsh discipline practices.

Design: Interviews with parents and pediatricians to compare pediatric detection of domestic violence and child abuse with parental reports of domestic violence and harsh discipline practices.

Setting: Community-based pediatric practices in the 13-town greater New Haven, Conn, area.

Participants: Of the 23 practices invited, 19 agreed to participate. Of the 2006 parents …

Cloning: A Jewish Law Perspective With A Comparative Study Of Other Abrahamic Traditions, Stephen J. Werber

Law Faculty Articles and Essays

This Article does not provide answers to the religious, ethical, and moral issues posed by advanced reproductive techniques in human cloning. Rather, the preceding analysis and discussion seeks to make a contribution, however modest, to the continuation of the societal discussion that will ultimately yield the answers. This Article presents the common concerns of the religious traditions of Judaism, Islam, and Christianity with their mutual emphasis on preserving the dignity of all beings. This and other common values must form the foundation upon which all questions related to the cloning debate must be predicated.

Continuous Passive Motion And Physical Therapy Versus Physical Therapy Alone In Total Knee Arthroplasty, Neal A. Cashman

Physical Therapy Scholarly Projects

This study investigated the effect of continuous passive motion (CPM) on the rehabilitation of patients undergoing total knee arthroplasty (TKA). Over the years, CPM use in the treatment of TKA has been debated whether it is effective enough to justify the medical expense that accompanies it.

Sixteen subjects who underwent TKA surgery participated in the study. Twelve subjects were in the CPM group and four subjects were in the non-CPM group. Groups were determined by the surgeon's rehabilitation preference of using the CPM or not using the CPM.

Post surgical subjects were treated with the CPM and physical therapy or …

The Effects Of Hormone Replacement Therapy And Exercise On Osteoporosis In Postmenopausal Females, Sara L. Glas

Physical Therapy Scholarly Projects

Osteoporosis is a debilitating and life-threatening disease affecting millions of people in the United States yearly, but most notably menopausal females. The lowered estrogen levels associated with menopause increase the chances of developing osteoporosis. Hormone Replacement Therapy (HRT) has been found to be one of the most beneficial therapies for slowing the progression of the disease. While some women are not candidates for this care and others take HRT solely for the relief of postmenopausal symptoms, studies have proven HRT has a long-term advantage against osteoporosis. Weight-bearing exercise has established efficacy through research proving its positive effect on bone formation …

Outcome Based Study On The 1999 Und-Pt Curriculum, Jenny Keil

Physical Therapy Scholarly Projects

The purpose of this study is to assess one component of the educational outcomes of the UND-PT curriculum. It is necessary to develop outcome assessment for many reasons. First, schools need to meet the needs of accreditation, such as the Committee on Accreditation of Physical Therapy Education. Second, students need to meet the needs of employers and patients to provide quality care. Finally, physical therapy programs must meet the needs of the graduates, who are entitled to a quality education and must be competent in practicing physical therapy.

Questionnaires were mailed out to the 50 graduate physical therapy students in …

Predictors Of Academic Success In The University Of North Dakota Master Of Physical Therapy Program, Christine W. Thorne

Physical Therapy Scholarly Projects

Because the number of qualified applicants far exceeds the number of positions currently available in this program, the admissions committee at the University of North Dakota (UND) is obligated to select students who possess the greatest ability to succeed in the program and later in the profession. The purpose of this retrospective study was twofold: (1) to determine which variables, academic and nonacademic, contribute the most to student academic and clinical success in the University of North Dakota's Physical Therapy (UND-PT) program and (2) to review the current admission process while looking for new predictors of academic and clinical success. …

Oncolog, Volume 45, Number 01, January 2000, Dawn Chalaire, Kerry L. Wright, Rena Sellin Md

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Pediatric Brain Tumor Studies Focus on Reducing Side Effects, Locating Biological Targets
• Retinoid Chemoprevention Trial Aims to Reverse Genetic Changes Caused by Smoking
• DiaLog: Surviving Cancer and Staying Healthy, by Rena Sellin, MD, Professor, Department of Internal Medicine Specialties
• House Call: From Biopsy to Diagnosis: Understanding the Process
• Protocols: Pediatric Brain Tumor Clinical Trials
• Protocols: Chemoprevention Studies Feature a Variety of Agents

The Potential Role Of Contraception In Reducing Abortion, John Bongaarts, Charles F. Westoff

Poverty, Gender, and Youth

Since the 1960s the proportion of couples practicing contraception has risen rapidly, particularly in the developing world, and the mix of methods is now dominated by modern methods. Despite these trends, the incidence of unintended pregnancy remains high mainly because the number of children desired has declined. Worldwide there are almost as many unintended as intended pregnancies each year (not counting miscarriages, which are excluded in this analysis) and more than half of these unintended pregnancies end in abortion. This study examines the potential role of further increases in contraceptive prevalence and effectiveness in reducing abortion rates. The model used …

Future Trends In Contraception In The Developing World: Prevalence And Method Mix, John Bongaarts, Elof D.B. Johansson

Poverty, Gender, and Youth

The main objectives of this study are to review existing methodologies for projecting future trends in contraception, evaluate the validity of the assumptions underlying these projections, propose methodological improvements, and assess the prospects for new methods of contraception in the coming decade. The prevalence of contraception in the developing world has increased dramatically over the past several decades from near zero to around 60 percent in 2000. Demand for contraception can be expected to continue to rise rapidly for the next few decades as population size continues to grow and fertility declines further to near the replacement level. As a …

Acute Phase Effect Of Trichloroethylene Ingestion On Some Biological Markers In Dogs, Recep Aslan, Mehmet Tütüncü, S. Oktay Aslan, Yilmaz Dündar

Turkish Journal of Veterinary & Animal Sciences

Trichloroethylene (TE) is an environmental toxic solvent hazardous to human and domestic animals and well known in the industrial sector. The purpose of this study was to determine whether oral TE plays a role in lipid oxidation and tissue damage. Fourteen dogs were treated with an oral toxic dose of 0.5 ml/kg T.E. The acute changes that occurred in creatine kimase (CK), malondialdehyte (MDA), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) were investigated in blood samples taken before application and 8, 24, 48, 72 and 168 hours after treatment. SOD and GSH-Px activities decreased, protein, albumin and alcalen phosphate did …

Determination Of Free Fatty Acid Composition In Plasma Membranes Of Neutrophils In Diabetics, Mevlüt Sai̇t Keleş, Yaşar Demi̇r, İrfan Altuntaş, Zuhal Umudum, Ebubeki̇r Bakan

Turkish Journal of Medical Sciences

Since frequent and serious infections occur in diabetic patients, the investigation of the function of neutrophils is of importance. Any change in the lipid composition of the plasma membrane could be one of the causes of these infections. In order to investigate this possibility and to determine any abnormalities, neutrophils and monocytes were separated by the Histopaque- 1119 method from the blood samples (20 ml) of 10 diabetic and 10 healthy persons. After disruption of the cells, membrane lipids and proteins were isolated. Free fatty acids of phospholipids in membrane lipids were isolated by hydrolysing with phospholipase B under an …

Biological Dosimetry Following X-Ray Irradiation, Münevver Coşkun, Asli Top, Tuncay Orta

Turkish Journal of Medical Sciences

Control radiation dose-response curves are necessary in evaluating the absorbed radiation dose of similar radiation quality following radiation accidents or in monitoring the health of both the public and radiation workers. Each biological dosimetry laboratory should establish its own control dose-response data. In this study our aim was to establish control curves for 200 kVp X-rays in our laboratory in order to estimate absorbed radiation doses following exposures. Blood samples from healthy individuals with no radiation working history were irradiated in heparinized tubes at 10 different doses 0.10-5.00 Gy. Cells from irradiated whole blood were incubated in culture containing phytohemagglutinin …

Adsorption Of Iron Or Ferritin By Chitosan, Şi̇nasi̇ Özsoylu

Turkish Journal of Medical Sciences

No abstract provided.

Tsc3p Is An 80-Amino Acid Protein Associated With Serine Palmitoyltransferase And Required For Optimal Enzyme Activity, Ken Gable, Harry Slife, Dagmar Bacikova, Erin Monaghan, Teresa M. Dunn

Uniformed Services University of the Health Sciences

Serine palmitoyltransferase catalyzes the first step of sphingolipid synthesis, condensation of serine and palmitoyl CoA to form the long chain base 3-ketosphinganine. The LCB1/TSC2 and LCB2/TSC1 genes encode homologous proteins of the a-oxoamine synthase family required for serine palmitoyltransferase activity. The other a-oxoamine synthases are soluble homodimers, but serine palmitoyltransferase is a membrane-associated enzyme composed of at least two subunits, Lcb1p and Lcb2p. Here, we report the characterization of a third gene, TSC3, required for optimal 3-ketosphinganine synthesis in Saccharomyces cerevisiae. S. cerevisiae cells lacking the TSC3 gene have a temperature-sensitive lethal phenotype that is reversed by supplying …

Escherichia Coli O157:H7 In Beef Cattle Presented For Slaughter In The U.S.: Higher Prevalence Rates Than Previously Estimated, Lisa J. Gansheroff, Alison D. O'Brien

Uniformed Services University of the Health Sciences

Before 1982, the Centers for Disease Control and Prevention (CDC) had identified only one Escherichia coli isolate of the O157:H7 serotype; it had been isolated from a patient with bloody diarrhea. Then, in 1982, two outbreaks of severe bloody diarrhea occurred among people who had eaten hamburgers at a fast food chain. The CDC isolated E. coli O157:H7 from people who had become ill as well as from a hamburger patty. In 1983, Karmali et al. discovered an association between infection with E. coli that produce Shiga toxin (then called Vero toxin), including O157:H7 strains, and another severe and sometimes …

Catalog (2000-2001, 2001-2002), Philadelphia College Of Osteopathic Medicine

Catalogs

A snapshot of the PCOM curriculum throughout the decades.