Digital Commons Network^™

Bacteriolytic Activity Of Selected Vertebrate Sera For Borrelia Burgdorferi Sensu Stricto And Borrelia Bissettii, Amy J. Ullmann, Robert S. Lane, Klaus Kurtenbach, Michael Miller, Martin E. Schriefer, Nordin Zeidner, Joseph Piesman

United States Public Health Resources

An in vitro assay to evaluate the bacteriolytic activity of the complement pathway was applied to 2 strains of Borrelia bissettii, CO501 and DN127, and compared with that of B. burgdorferi sensu stricto B31. Sera from mule deer ( Odocoileus hemionus) and the Western Fence lizard ( Sceloporus occidentalis) were completely borreliacidal for B. burgdorferi and for both strains of B. bissettii. Serum from Bobwhite quail ( Colinus virginianus) was nonlytic for B. burgdorferi and partially lytic for B. bissettii strains, CO-501 and DN127. Serum from a New Zealand White rabbit ( Oryctolagus cuniculus) …

Acknowledgements, The Mcnair Team

McNair Scholars Research Journal

No abstract provided.

Barriers To Lesbian Health Care, Paula Bowles

Masters Theses & Specialist Projects

The primary purpose of this research was to examine a sample of sixteen lesbian women regarding the barriers to lesbian health-care. From this information several interpretive findings regarding lesbian health-care are made. Data were gathered via indepth interviews with each individual lesbian. The data suggest that most lesbian women do not reveal their sexual orientation to their primary-care physician for fear of reprisal. Most of the women interviewed do feel they receive adequate health-care from their physician. The women who participated in this project did so confidentially and were assigned pseudonyms. They were asked questions on a variety of topics, …

Comparison Of Bracket Bond Strength By Total, Self-Etch And Laser Treatment, Kyo Sung Shawn Kim

Loma Linda University Electronic Theses, Dissertations & Projects

Laser etching of enamel surfaces alters the physical and chemical characteristics of the enamel. These changes in characteristics enhance the bonding to enamel. The purpose of this study was to compare the shear and tensile bond strength of Er,Cr:YSGG hydrokinetic laser system (Biolase) with 37% phosphoric acid and self etching primer 30 minutes and 72 hours after bonding. Four different laser power output setting was observed: 1.5W, 2.0W, 2.5W, and 3.0W. Two hundred forty bovine teeth free of defect, caries, and dentin exposure were mounted in acrylic resin and divided into 24 groups of 10 teeth. Sixteen groups of 10 …

Clinical Effectiveness Of A Subperiosteal Anchorage Device, Monica Anne Witte

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this pilot study was to evaluate the clinical efficacy of a subperiosteal anchorage device, the palatal OnPlant™, during orthodontic retraction of protruding anterior teeth in cases requiring maxillary premolar extraction. Seven subjects (5 female, 2 male), ages 13 to 55, were selected for the study. The OnPlant was surgically placed in the mid-palatal region through a well-defined subperiosteal tunnel. Following the manufacturer recommended osseointegration period of four months, the OnPlant was uncovered and attached to the first molars by means of a transpalatal bar. Standard orthodontic treatment then commenced to retract the anterior teeth after the first …

Does Exercise And Placement Technique Affect Triceps Surae Thermocouple Position As Measured By Magnetic Resonance Imaging?, Breanne A. Piatt

All-Inclusive List of Electronic Theses and Dissertations

Context: Intramuscular temperatures are commonly recorded with the use of implantable thermocouples. Currently, there are 2 techniques of inserting intramuscular thermocouples, a traditional technique, which inserts the thermocouple with a sterile hypodermic needle, then retracts the needle, and a catheter-assisted technique, which uses a spring-loaded catheter to insert the catheter then a thermocouple is fed through the catheter to target position. Objective: The purpose of this study was first to investigate whether or not target position is obtained with either insertion method. A second purpose of this study was to quantify the amount of movement that occurs after exercise. Lastly, …

Full Issue, The Mcnair Team

McNair Scholars Research Journal

No abstract provided.

Determination Of The Optimal Form Of A Dna Vaccine To Induce An Effective Immune Response Against A Murine B-Cell Lymphoma, Deepti Aurora

All-Inclusive List of Electronic Theses and Dissertations

Tumor vaccines are a promising alternative to chemotherapy for the treatment of cancer. To be effective and safe, a cancer vaccine should specifically target antigens expressed only on tumor cells. The B-cell tumor-derived Ig receptor may be considered a model tumor antigen for cancer vaccine development. Specifically the immunoglobulin idiotype (ld) encoded by the variable region genes (VH and VL) provides a target antigen. Promising results have been obtained in clinical studies of ld vaccination using ld proteins. However, ld protein is laborious and time-consuming to produce. Gene-based vaccines, on the other hand, are inexpensive and offer ease of manipulation …

The Histological Effects Of Mandibular Distraction Osteogenesis On Rabbit Condyles, Eunice Jungmin Hong

Loma Linda University Electronic Theses, Dissertations & Projects

The present study is a histological evaluation of condyles taken from rabbits that underwent either a midline or paramedian distraction osteogenesis procedure on the mandibles. Fifteen rabbits were originally operated on and eight of these fifteen successfully made it through both the distraction osteogenesis procedure and the 1 month holding period that followed. There was one control animal.

In the present study, the condyles from these nine rabbits (1 control, 2 midline distraction osteogenesis, 6 paramedian distraction osteogenesis) were prepared for histological evaluation (18 total). Step serial sections were cut along the coronal plane and the sections from the anterior …

Resiliency Factors Related To Substance Use/Resistance: Perceptions Of Native Adolescents Of The Southwest, Margaret A. Waller, Scott K. Okamoto, Bart Miles, Donna E. Hurdle

The Journal of Sociology & Social Welfare

This exploratory, qualitative study examined risk and protective factors influencing drug and alcohol use and/or resistance of Native youth in the Southwest. Thirty-two Native middle school students participated in 10 focus groups that explored their experiences with alcohol and drugs in their school and reservation communities. The findings indicate a complex interaction of both risk and protective factors related to substance use. Respondents' cousins and siblings, in particular, played a key role in their decisions to use or resist drugs. Implications for social work practice are discussed.

Arkansas Animal Science Department Report 2003, Zelpha B. Johnson, D. Wayne Kellogg

Arkansas Agricultural Experiment Station Research Series

The faculty and staff of the Animal Science Program are pleased to present the sixth edition of the Arkansas Animal Science Report. As with virtually all programs in the country, budget constraints presented serious challenges to teaching, research, and extension programming. However, the faculty and staff responded with innovation, good management, and hard work to maintain a productive program designed to benefit the students of the University and the citizens of the state. We are committed to remaining faithful to our Land-Grant mission. A sincere thank you is owed to Dr. Zelpha Johnson and Dr. Wayne Kellogg for editing this …

Mammalian Ggas Act Together To Sort Mannose 6-Phosphate Receptors, Pradipta Ghosh, Janice Griffith, Hans J. Geuze, Stuart Kornfeld

Open Access Publications

No abstract provided.

Time-Series Studies Of Particulate Matter, Michelle L. Bell, Jonathan M. Samet, Francesca Dominici

Johns Hopkins University, Dept. of Biostatistics Working Papers

Studies of air pollution and human health have evolved from descriptive studies of the early phenomena of large increases in adverse health effects following extreme air pollution episodes, to time-series analyses and the development of sophisticated regression models. In fact, advanced statistical methods are necessary to address the many challenges inherent in the detection of a small pollution risk in the presence of many confounders. This paper reviews the history, methods, and findings of the time-series studies estimating health risks associated with short-term exposure to particulate matter, though much of the discussion is applicable to epidemiological studies of air pollution …

Ada News - 11/17/2003, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Embryonic Origins Of A Motor System: Motor Dendrites Form A Myotopic Map In Drosophila, Matthias Landgraf, Victoria Jeffrey, Miki Fujioka, James B. Jaynes, Michael Bate

Department of Biochemistry and Molecular Biology Faculty Papers

The organisational principles of locomotor networks are less well understood than those of many sensory systems, where in-growing axon terminals form a central map of peripheral characteristics. Using the neuromuscular system of the Drosophila embryo as a model and retrograde tracing and genetic methods, we have uncovered principles underlying the organisation of the motor system. We find that dendritic arbors of motor neurons, rather than their cell bodies, are partitioned into domains to form a myotopic map, which represents centrally the distribution of body wall muscles peripherally. While muscles are segmental, the myotopic map is parasegmental in organisation. It forms …

A Corrected Pseudo-Score Approach For Additive Hazards Model With Longitudinal Covariates Measured With Error, Xiao Song, Yijian Huang

UW Biostatistics Working Paper Series

In medical studies, it is often of interest to characterize the relationship between a time-to-event and covariates, not only time-independent but also time-dependent. Time-dependent covariates are generally measured intermittently and with error. Recent interests focus on the proportional hazards framework, with longitudinal data jointly modeled through a mixed effects model. However, approaches under this framework depend on the normality assumption of the error, and might encounter intractable numerical difficulties in practice. This motivates us to consider an alternative framework, that is, the additive hazards model, under which little has been done when time-dependent covariates are measured with error. We propose …

Synthases, Joseph Chappell, Kathleen R. Manna, Joseph P. Noel, Courtney M. Starks

Pharmaceutical Sciences Faculty Patents

Novel synthases and the corresponding nucleic acids encoding such synthases are disclosed herein. Such synthases possess an active site pocket that includes key amino acid residues that are modified to generate desired terpenoid reaction intermediates and products. Synthase modifications are designed based on, e.g., the three-dimensional coordinates of tobacco 5-epi-aristolochene synthase, with or without a substrate bound in the active site.

Parenting Characteristics Of Women Reporting A History Of Childhood Sexual Abuse, David Dilillo, Amy Damashek

Department of Psychology: Faculty Publications

This article reviews research on the parenting characteristics of female survivors of childhood sexual abuse (CSA). Various aspects of parenting are considered, including (a) childbearing patterns, (b) the intergenerational transmission of CSA, (c) maternal reactions to child CSA disclosure, (d) parenting skills and behaviors, (e) parental violence toward children, (f) attitudes toward parenting, and (g) adjustment of survivors’ children. Overall patterns suggest CSA survivors may experience difficulties with some aspects of parenting. Among the more consistent trends are findings that survivors may have difficulties establishing clear generational boundaries with their children, may be more permissive as parents, and may be …

Rural Health Care In The Electronic Age (Danville, Pa), Lisa Sprague, Nora Super

National Health Policy Forum

This site visit to the Geisinger Health System in central Pennsylvania explored the use of technology in providing health care to an aging, rural population with a high index of chronic-care needs. The agenda included an in-depth examination of Geisinger’s electronic medical record and its use in various domains of care, including outpatient clinics, disease management, and non-Geisinger medical practices and community hospitals. The program also highlighted specific care management initiatives in the areas of radiology, stroke, and obesity. Geisinger’s advantages as an integrated system dominant in its market, with the resources to invest in technology were weighed in considering …

Ada News - 11/03/2003, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Flight Physician - November, 2003, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A twenty-four page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.

Inside Unlv, Gian Galassi, Cayrn Key, Carol C. Harter, Patrick Ferrillo

Inside UNLV

No abstract provided.

Oncolog, Volume 48, Number 11, November 2003, Sunni Hosemann, Don Norwood

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Laparoscopy Shows a Benefit in a Growing Number of Oncologic Procedures
• Collaboration and Creativity Lead to a New Approach to Spinal Surgery
• Protocols: Studies Test New Surgical Procedures
• House Call: Telling Fact from Fiction on the Internet

Reconstructing The Genomic Architecture Of Mammalian Ancestors Using Multispecies Comparative Maps, William J. Murphy, Guillaume Bourque, Glenn Tesler, Pavel Pevzner, Stephen J. O'Brien

Biology Faculty Articles

Rapidly developing comparative gene maps in selected mammal species are providing an opportunity to reconstruct the genomic architecture of mammalian ancestors and study rearrangements that transformed this ancestral genome into existing mammalian genomes. Here, the recently developed Multiple Genome Rearrangement (MGR) algorithm is applied to human, mouse, cat and cattle comparative maps (with 311-470 shared markers) to impute the ancestral mammalian genome. Reconstructed ancestors consist of 70-100 conserved segments shared across the genomes that have been exchanged by rearrangement events along the ordinal lineages leading to modern species genomes. Genomic distances between species, dominated by inversions (reversals) and translocations, are …

Presentation Of Allergen In Different Food Preparations Affects The Nature Of The Allergic Reaction: A Case Series, K. E. C. Grimshaw, R. M. King, Julie A. Nordlee, S. L. Hefle, John O. Warner, J. O.'B. Hourihane

Department of Food Science and Technology: Faculty Publications

Background: Characterization of fatal and nonfatal reactions to food indicates that the majority of reactions are due to the ingestion of prepared foods rather than the nonprocessed allergen. In an ongoing study that used a double-blind placebo-controlled food challenge to investigate peanut allergy and clinical symptoms, the observed reaction severity in four of the first six subjects was greater than anticipated. We hypothesized that this was due to differences in the composition of the challenge vehicle.

Objective: The aim was to investigate whether the severity of observed challenge reactions would be repeated on rechallenge with a lower fat …

In Vitro Analog Of Classical Conditioning Of Feeding Behavior In Aplysia, Riccardo Mozzachiodi, Hilde A. Lechner, Douglas A. Baxter, John H. Byrne

Faculty, Staff and Student Publications

The feeding behavior of Aplysia californica can be classically conditioned using tactile stimulation of the lips as a conditioned stimulus (CS) and food as an unconditioned stimulus (US). Moreover, several neural correlates of classical conditioning have been identified. The present study extended previous work by developing an in vitro analog of classical conditioning and by investigating pairing-specific changes in neuronal and synaptic properties. The preparation consisted of the isolated cerebral and buccal ganglia. Electrical stimulation of a lip nerve (AT4) and a branch of the esophageal nerve (En2) served as the CS and US, respectively. Three protocols were used: paired, …

Bioethics: Everything You Wanted To Know About Life Or Death, But Were Afraid To Ask, St Mary's University

President's Peace Commission - Programs

The President’s Peace Commission existed from 1984 to 2013 at St. Mary's University. The Commission fostered an ethical commitment to participate in the establishment of world peace and social justice.

This program is about genetic technologies, ethical issues in human and animal experimentation and physician assisted suicide.

Transcriptional Inhibition Of Type I Collagen Gene Expression In Scleroderma Fibroblasts By The Antineoplastic Drug Ecteinascidin 743., Natalia Louneva, Biagio Saitta, David J Herrick, Sergio A. Jimenez

Department of Medicine Faculty Papers

We previously showed that COL1A1 expression is up-regulated at the transcriptional level in systemic sclerosis (SSc) fibroblasts and that the CCAAT-binding factor (CBF) is involved in this increased expression. Ecteinascidin 743 (ET-743) is a chemotherapeutic agent that binds with sequence specificity to the minor groove of DNA and inhibits CBF-mediated transcriptional activation of numerous genes. Therefore, we examined the effects of ET-743 on the increased COL1A1 expression in SSc fibroblasts. The drug caused a potent and dose-dependent inhibition of type I collagen biosynthesis, which reached 70-90% at 700 pM without affecting cell viability. The same drug concentration caused 60-80% reduction …

Effects Of A Supportive-Education Nursing Intervention On Quality Of Life In Patients With Heart Failure, Melodee L. Vanden Bosch

Masters Theses

The purpose of this secondary analysis was to examine the difference in quality of life (QOL) in home-care patients with heart failure (HF) receiving nursing intervention. The specific nursing intervention of interest was supportive-education (SE), based on Orem's (1995) self-care deficit theory. The second intervention of general health teaching acted as a placebo effect. The convenience sample of randomly assigned patients with HF was from two home-care agencies. The paired t-test was used to analyze the difference in QOL within the SE group and the placebo group from baseline to six months. The independent t-test was used to compare the …

Stem Cell Research?: Yes--Out Of Love For The Neighbor, Alan G. Padgett

Faculty Publications

No abstract provided.