Digital Commons Network^™

The Association Of Blood Type On The Five Factors Of Personality In Chinese Adolescents, Kunher Wu

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to identify the number of personality factors in Chinese adolescents using the Chinese Revised NEO Personality Inventory (NEO-PI-R) and to determine whether blood type is associated with personality. It is widely accepted by psychologists that the five-factor model can provide an adequate representation of adult personality dimensions, but there is less agreement on the number of factors observable in adolescence. A total of 3,396 11^th graders from the city of Kaohsiung, Taiwan completed the Chinese NEO-PI-R. Principle component analysis with varimax rotation showed five factors of personality in these Taiwanese adolescents, which clearly …

Bronchiolitis Obliterans Organizing Pneumonia Associated With Cytomegalovirus Infection In A Patient With Systemic Lupus Erythematosus., Muhammad Irfan, Ali Bin Sarwar Zubairi, S.J. Husain

Department of Medicine

No abstract provided.

Osha Laboratory Safety Standard 29 Cfr 1910.1450 And Achieving Compliance In The Microelectronic Laboratory, Danielle M. Digironimo

Theses

This thesis is a practical application of occupational exposures to hazardous substances in a microelectronics laboratory. The Occupational Safety and Health Administration (OSHA) standard for the safety in laboratories is (29 CFR 1910.1450). The application is a demonstration of the implementation of the standard in a university setting. Hazards that exist in laboratory settings are very complex and the task of providing a safe workplace can become increasingly complicated. A laboratory can and does impose different health and safety concerns that a standard industrial workplace setting might not have. The need for a laboratory safety standard program to be implemented …

Mathematical Modeling Of Transient State Transdermal Drug Delivery, Alison Nickol Weltner

Theses

In this work, a two-pathway mathematical model for transdermal drug delivery with iontophoresis is presented. The partial differential equations are described and then solved. An alternative, two-pathway, three-layer model is also presented, and the implications of the coefficients within the equation are discussed. Using Franz cell iontophoretic delivery data from three drug substances (amitriptyline HCl, clomipramine HCl, and nortriptyline HCl), the two-pathway model is regressed to determine the diffusion coefficient and the concentration within the skin at the drug reservoir interface. ANOVA analysis indicates a correlation between iontophoretic current and concentration of drug within the stratum corneum.

Predicting The Use Of Personal Respiratory Protection Among Workers In Swine Confinement Buildings, M. Susan Jones

Nursing Faculty Publications

The purpose of this study was to identify the variables that influence the frequency of personal respiratory protection (PRP) use by workers in swine confinement buildings (SCBs). The study was designed to answer four research questions: 1). What is the validity and reliability of the Personal Respiratory Protection Survey (PRPS)? 2). How frequently do workers in SCBs wear PRP? 3). How do demographics, occupational histories, and self-reported respiratory health histories influence the use of PRP in SCBs? and 4). What are the relationships of the constructs (benefits, barriers, susceptibility, severity, norms) to the use of PRP by workers in SCBs? …

Endogenous No Regulates Superoxide Production At Low Oxygen Concentrations By Modifying The Redox State Of Cytochrome C Oxidase, Miriam Palacios-Callender, Marisol Quintero, Veronica S. Hollis, Roger J. Springett, Salvador Moncada

Dartmouth Scholarship

We have investigated in whole cells whether, at low oxygen concentrations ([O(2)]), endogenous nitric oxide (NO) modulates the redox state of the mitochondrial electron transport chain (ETC), and whether such an action has any signaling consequences. Using a polarographic-and-spectroscopic-coupled system, we monitored redox changes in the ETC cytochromes b(H), cc(1), and aa(3) during cellular respiration. The rate of O(2) consumption (VO(2)) remained constant until [O(2)] fell below 15 microM, whereas the onset of reduction of cytochromes aa(3), part of the terminal ETC enzyme cytochrome c oxidase, occurred at approximately 50 microM O(2). Incubation of the cells with an inhibitor of …

Ada News - 05/17/2004, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Louisiana State University Health Sciences Center - 2004 - 126th Commencement, Office Of The Registrar, Lsu Health Sciences Center-No

Graduation & Commencement Programs

The program for the 126th Commencement of LSU Health Sciences Center - New Orleans held May 15, 2004.

Methods To Impair Hematologic Cancer Progenitor Cells And Compounds Related Thereto, Craig Jordan

Internal Medicine Faculty Patents

Primitive or progenitor hematologic cancer cells have been implicated in the early stages and development of leukemia and malignant lymphoproliferative disorders, including acute myelogenous leukemia (AML), chronic myelogenous leukemia (CML) and chronic lymphoid leukemia (CLL). Interleukin-3 receptor alpha chain (IL-3Rα or CD123) is strongly expressed on progenitor hematologic cancer cells, but is virtually undetectable on normal bone marrow cells. The present invention provides methods of impairing progenitor hematologic cancer (e.g., leukemia and lymphomic) cells by selectively targeting cells expressing CD123. These methods are useful in the detection and treatment of leukemias and malignant lymphoproliferative disorders. Also provided are compounds useful …

On Corrected Score Approach For Proportional Hazards Model With Covariate Measurement Error, Xiao Song, Yijian Huang

UW Biostatistics Working Paper Series

In the presence of covariate measurement error with the proportional hazards model, several functional modeling methods have been proposed. These include the conditional score estimator (Tsiatis and Davidian, 2001), the parametric correction estimator (Nakamura, 1992) and the nonparametric correction estimator (Huang and Wang, 2000, 2003) in the order of weaker assumptions on the error. Although they are all consistent, each suffers from potential difficulties with small samples and substantial measurement error. In this article, upon noting that the conditional score and parametric correction estimators are asymptotically equivalent in the case of normal error, we investigate their relative finite sample performance …

Ada News - 05/03/2004, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

The Cell Surface Receptor Slam Controls T Cell And Macrophage Functions, Ninghai Wang, Abhay Satoskar, William Faubion, Susumu Okamoto, Stefan Feske, Charles A. Gullo Phd, Kareem Clarke, Miriam Rodriguez Sosa, Arlene H. Sharpe, Cox Terhorst

Biochemistry and Microbiology

Signaling lymphocyte activation molecule (SLAM), a glycoprotein expressed on activated lymphocytes and antigen-presenting cells, has been shown to be a coregulator of antigen-driven T cell responses and is one of the two receptors for measles virus. Here we show that T cell receptor–induced interleukin (IL)-4 secretion by SLAM−/− CD4+ cells is down-regulated, whereas interferon γ production by CD4+ T cells is only slightly up-regulated. Although SLAM controls production of IL-12, tumor necrosis factor, and nitric oxide in response to lipopolysaccharide (LPS) by macrophages, SLAM does not regulate phagocytosis and responses to peptidoglycan or CpG. Thus, SLAM acts as a coreceptor …

Genetic Analysis Of The Putative Streptolysin O Regulator From Streptococcus Pyogenes, Robert Tyrone Billingslea

McCabe Thesis Collection

Group A streptococci (Streptococcus pyogenes) is one of the most frequent pathogens of humans. It is estimated that between 5-15% of normal individuals harbor the bacterium, usually in the upper respiratory tract, without signs of disease. S. pyogenes can initiate an active infection when defenses are compromised or when the organism is able to penetrate the host's defenses. When the bacteria invade vulnerable tissues, a variety of suppurative infections can occur. Acute S. pyogenes infection may be present as pharyngitis ("strep throat"), scarlet fever (rash), impetigo (infection of the superficial layers of the skin) or cellulitis (infection of the deep …

Information Interface - Volume 32, Issue 2 - May/June 2004, George Washington University, Himmelfarb Health Sciences Library

Information Interface (1976 - 2009)

News and information about Himmelfarb Health Sciences Library of interest to users. Includes articles on medical publishing, AHEC summer program, a journals shift project, and database search tips.

Black And White: Structural And Functional Aspects Of Dermal Chromatophores Of The Marbled Whiptail Lizard (Cnemidophorus Marmoratus), James Swan

Masters Theses & Specialist Projects

The skin of reptiles is a complex organ with many sensory, regulatory and behavioral functions. Desert reptiles face a suite of challenges as their skin contacts hot-dry environmental surfaces. The marbled whiptail lizard, Cnemidophorus marmoratus (Lacertilia: Teiidae), is found in hot deserts of southeastern New Mexico and western Texas and is often above ground during the hottest times of the day. When active, these lizards encounter a broad range and intensity of visible and infrared wavelengths. The role of the integument in temperature regulation, although poorly understood, is critically important for these diurnal animals. Albedo, coloration, pattern, and in some …

Differences In Peripheral Noradrenergic Function Among Actively Drinking And Abstinent Alcohol-Dependent Individuals., Ashwin A. Patkar, Charles A. Marsden, Prakash C. Naik, David A. Kendall, Raman Gopalakrishnan, Michael J. Vergare, Stephen P. Weinstein

Department of Psychiatry and Human Behavior Faculty Papers

We examined whether excessive alcohol consumption was related to changes in plasma levels of noradrenaline (NA) and whether these changes recover following abstinence. We also explored whether there were differences in NA levels between Type I and Type II alcoholics and controls during active drinking and abstinence. Plasma concentrations of NA were determined in (1) 27 Caucasian men with alcohol dependence who were regularly drinking (active drinkers) within 24 hours of hospitalization, (2) 29 Caucasian alcohol-dependent men who were in remission (abstinent for a minimum of three months), and (3) 28 race- and gender-matched healthy controls. NA concentrations were significantly …

Identification Of A Novel Bovine Herpesvirus 1 Transcript Containing A Small Open Reading Frame That Is Expressed In Trigeminal Ganglia Of Latently Infected Cattle, Melissa Inman, Joe Zhou, Heather Webb, Clinton J. Jones

School of Veterinary and Biomedical Sciences: Faculty Publications

Bovine herpesvirus 1 (BHV-1), like other Alphaherpesvirinae subfamily members, establishes latency in sensory neurons. The latency-related (LR) RNA is abundantly expressed during latency, and expression of an LR protein is required for the latency reactivation cycle in cattle. Within LR promoter sequences, a 135-aminoacid open reading frame (ORF) was identified, ORF-E, that is antisense to the LR RNA. ORF-E is also downstream of the gene encoding the major viral transcriptional activator, bICP0. Strand-specific reverse transcription-PCR demonstrated that a transcript containing ORF-E was consistently expressed in trigeminal ganglia (TG) of latently infected calves, productively infected cultured cells, and acutely infected calves. …

Acetylcholine Protection Of Adult Pig Retinal Ganglion Cells From Glutamate-Induced Excitotoxicity, Erica Wehrwein, Sean A. Thompson, Sylvie F. Coulibaly, David M. Linn, Cindy L. Linn

Peer Reviewed Articles

PURPOSE. To determine which glutamate receptor (GluR) subtypes are responsible for glutamate-induced excitotoxicity in cultured adult pig retinal ganglion cells (RGCs) and to characterize the neuroprotective effect of acetylcholine (ACh) on pig RGCs.

METHODS. Adult pig RGCs were isolated from other retinal tissue by a modified panning technique using Thy 1.1 antibody. Isolated RGCs were cultured in control media and media containing: glutamate, NMDA, or KA; glutamate and CNQX, MK-801, or AP-7; ACh, nicotine or muscarine; ACh and α-bungarotoxin (Bgt) or methyllycaconitine (MLA); and glutamate and choline or glutamate, choline, and MLA. To determine cell viability, cells were …

Art Therapy As A Measure Of Children’S Concept Of Surgery: A Preliminary Study, Emily C. Clark

EVMS School of Health Professions Theses & Dissertations

Surgery is a strange, and often frightening experience for children. A number of programs have been studied which attempt to prepare children for the surgery experience. Art therapy may be especially suited to help prepare children for surgery because art making is an effective form of communication for children, and can allow them to express their thoughts and fears about surgery. Unfortunately, studies of art therapy preparation programs are rare, and usually take the form of case studies. This research study is the first step in designing an art therapy preparation program for preparing children for surgery.

The purpose of …

Attachment Strategies Of Adolescents In Foster Care: Indicators And Implications, Shannon Leigh Trewartha

EVMS School of Health Professions Theses & Dissertations

The purpose of this study was to explore the use of an art-based assessment to recognize the attachment strategy of adolescents in foster care. The extenuating circumstances of foster care make it imperative to develop a sensitive, accurate, and time-efficient tool. Knowledge of specific attachment strategy can better guide therapeutic interventions. This study examined adolescents’ attachment strategy as measured by the Adolescent Relationship Questionnaire (A-RSQ) in comparison to ratings on the Bird’s Nest Drawing (BND). Fourteen adolescents in foster care participated.

Due to the low number of participants, data was predominantly analyzed descriptively. On the A-RSQ, the sample had lower …

Visual Predictors Of Relapse In The Artwork Of Adult Substance Abusers, Danica Aimeè Vallery

EVMS School of Health Professions Theses & Dissertations

This study hypothesized that five visual predictors of relapse previously found statistically significant by Dickman, Dunn and Wolf (1996) and Williar (2002), in the artwork of adult substance abusers, would again be found statistically significant predictors of relapse, in the artwork of the group identified as a high risk for relapse in Williar’s study. The body of artwork studied included twenty-two previously acquired, studied, and archived drawings (Williar, 2002), created by 22 chemically dependent adults. All subjects completed the assessment of warning signs for relapse (AWARE)(Harris & Miller, 2000) and were grouped as either high or low risk for relapse …

A Cross-Cultural Study Of Children’S Development As Reflected In Their Artwork: An Investigation Of Children’S Drawings From The African Country Of Benin, Elizabeth Anna Smead

EVMS School of Health Professions Theses & Dissertations

This research adds to the body of knowledge related to the human figure drawing as a useful tool in assessment and to art therapists’ understanding of children who depict the human figure in cross-cultural settings. This researcher obtained a sample collection of 148 human figure drawings from African children in rural Benin, West Africa to study in comparison to a set of human figure drawings collected under similar conditions in Hampton Roads, Virginia.

In this quantitative study, five of the Formal Elements Art Therapy Scales (FEATS) were modified and used to tally the formal elements of each of the 148 …

Neuroscience: Its Relevance To Art Therapy And Art Therapy Education, Patrick Oates

EVMS School of Health Professions Theses & Dissertations

The development of contemporary neuroscience techniques has provided professionals in mental health fields with insight into the human brain and its functions. Literature searches revealed that there is very little research being conducted or existing literature that discusses the physiological response in the brain to the art therapy process. A more comprehensive understanding of the brain’s response to making art could enhance art therapists’ capacity to provide the most suitable treatment to meet the clients’ needs. This study was designed to explore the significance of neuroscience in art therapy, and art therapy education.

A questionnaire was emailed to 49 program …

The Elders, Finding Long Ago And Now, Our Elders Health Journey, Judy A. Erickson Jacoby

Theses and Dissertations

No abstract provided.

Age-Related Hearing Loss And Its Association With Reactive Oxygen Species And Mitochondrial Dna Damage, Michael D. Seidman, Nadir Ahmad, Dipa Joshi, Jake Seidman, Sujatha Thawani, Wayne S. Quirk

All Faculty Scholarship for the College of the Sciences

Age-related hearing loss, known as presbyacusis, is characterized by the progressive deterioration of auditory sensitivity associated with the aging process and is the leading cause of adult auditory deficiency in the USA. Presbyacusis is described as a progressive, bilateral, high-frequency hearing loss that is manifested on audiometric assessment by a moderately sloping pure tone audiogram. Approximately 23% of the population between 65 and 75 years of age, and 40% of the population older than 75 years of age are affected by this condition. It was estimated in 1980 that 11% of the population was 76 years or older and this …

Characterization Of Hemoglobin, Water, And Nir Scattering In Breast Tissue: Analysis Of Intersubject Variability And Menstrual Cycle Changes, Brian W. Pogue, Shudong Jiang, Hamid Dehghani, Christine Kogel, Sandra Soho, Subhadra Srinivasan, Xiaomei Song, Tor D. Tosteson, Steven P. Poplack, Keith D. Paulsen

Dartmouth Scholarship

Near-infrared imaging was used to quantify typical values of hemoglobin concentration, oxygen saturation, water fraction, scattering power, and scattering amplitude within the breast tissue of volunteer subjects. A systematic study of the menstrual variations in these parameters was carried out by measuring a group of seven premenopausal normal women (aged 41 to 47 years) in the follicular (days 7 to 14 of the cycle) and secretory phases (days 21 to 28) of the cycle, for two complete menstrual cycles. An average increase in hemoglobin concentration of 2.6 μM or 13% of the background breast values was observed in the …

Tuba, A Novel Protein Containing Bin/Amphiphysin/Rvs And Dbl Homology Domains, Links Dynamin To Regulation Of The Actin Cytoskeleton, Marco Antonio Del Valle Salazar

Yale Medicine Thesis Digital Library

Tuba is a novel scaffold protein that functions to bring together dynamin with components of the actin cytoskeleton. It is concentrated at synapses in brain and binds dynamin selectively through four N-terminal Src homology-3 (SH3) domains. Tuba binds a variety of actin regulatory proteins, including N-WASP, CR16, WAVE1, WIRE, PIR121, NAP1, and Ena/VASP proteins, via a C-terminal SH3 domain. Direct binding partners include N-WASP and Ena/VASP proteins. Forced targeting of the C-terminal SH3 domain to the mitochondrial surface can promote accumulation of F-actin around mitochondria. A Dbl homology domain present in the middle of Tuba upstream of a Bin/amphiphysin/Rvs (BAR) …

Neurology In The 21st Century: Contemporary State Of Diagnostics And Therapeutics, Saad Shafqat, Mohammad Wasay

Department of Medicine

Although neurological disease has been recognized since antiquity, neurology as a systematic clinical discipline is less than 130 years old. Neurological practice has traditionally been constrained by the complexity of the human nervous system, which has been slow to yield its secrets. Over the last three decades, however, clinical neurology has been transformed in terms of both diagnostics and therapeutics and now marches in lockstep with the cutting edge of medicine. Efficacious treatments are now available for the majority of neurological diseases, including epilepsy, migraine, Guillain-Barre syndrome, Parkinson's disease, multiple sclerosis, and ischemic stroke. This neurological revolution has been enabled …

Simulation Of Drosophila Circadian Oscillations, Mutations, And Light Responses By A Model With Vri, Pdp-1, And Clk, Paul Smolen, Paul E. Hardin, Brian S. Lo, Douglas A. Baxter, John H. Byrne

Faculty, Staff and Student Publications

A model of Drosophila circadian rhythm generation was developed to represent feedback loops based on transcriptional regulation of per, Clk (dclock), Pdp-1, and vri (vrille). The model postulates that histone acetylation kinetics make transcriptional activation a nonlinear function of [CLK]. Such a nonlinearity is essential to simulate robust circadian oscillations of transcription in our model and in previous models. Simulations suggest that two positive feedback loops involving Clk are not essential for oscillations, because oscillations of [PER] were preserved when Clk, vri, or Pdp-1 expression was fixed. However, eliminating positive feedback by fixing vri expression altered the oscillation period. Eliminating …

Investigation And Calculation Of Dose Coefficients For Radionuclides Produced In A Spallation Neutron Source Using The Ensdf And Nubase Nuclear Databases, Yayun Song

UNLV Theses, Dissertations, Professional Papers, and Capstones

Dose coefficients are useful for risk assessment during the design and siting of accelerator-driven nuclear facilities including the Spallation Neutron Source. There are seventy-two radionuclides with half-lives equal to or greater than one minute that will be produced by the spallation of a mercury target for which no published dose coefficients exist. Out of these seventy-two, twenty-four currently have conflicting published nuclear data in the Evaluated Nuclear Structure Data Files (ENSDF) and the NUBASE data files. In this research these twenty-four radionuclides have been studied. Because of missing ENSDF records, internal and external dose coefficients were determined for only six …