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The Impact Of Public Health Authority On Emergency Response In State Health Departments, Jessica L. Baggett

Dissertations: Doctor of Public Health

Background

Public health authority plays a crucial role in enabling state health officials to implement emergency response measures such as isolation, quarantine, and vaccination campaigns. However, legislative changes following the COVID-19 pandemic have significantly curtailed these authorities in many states, raising concerns about the ability of public health officials to respond effectively to future health crises. The erosion of public health authority has highlighted gaps in the legal literacy of health officials and underscored the need for enhanced training in navigating political and legal challenges.

Purpose

The purpose of this study is to assess legal literacy among state health officials, …

Implementing Early Detection Of Cognitive Impairment In Primary Care To Improve Care For Older Adults, Nicole R. Fowler, Katherine A. Partrick, James Taylor, Michael Hornbecker, Malaz Boustani, Jeffrey L. Cummings, Tim Macleod, Michelle M. Mielke, Jared R. Brosch, Chinedu Momoh

Brain and Mind Institute

Primary care is the ideal setting for early detection of mild cognitive impairment (MCI) and Alzheimer's disease and related dementias (ADRD), as it serves as the primary point of care for most older adults. With the growing aging population, reliance on specialists for detection and diagnosis is unsustainable, highlighting the need for primary care-led assessment. Recent research findings on successful brain health prevention strategies, AD diagnostic tools, and anti-amyloid treatments empower primary care to play a central role in early detection and intervention. Primary care-focused resources are being developed, including tools for cognitive assessments and materials designed to educate patients …

Relationship Between Past And Present Physical Activity On The Self-Reported Well-Being Of College-Aged Students With And Without Add/Adhd, Eleanore Cornn

Undergraduate Honors Thesis Collection

This study explores the relationship between past and present physical activity for college students with and without ADD/ADHD on their self-reported perceptions of well-being.

The Evolution Of Dental Aesthetics: An Artistic And Cultural Journey Through History And Race, Naya L. Weems

Undergraduate Honors Thesis Collection

This thesis explores the intersection of art, dentistry, race, and healthcare through a critical analysis of how visual culture has shaped societal perceptions of dental aesthetics from antiquity to the modern day. Beginning with ancient Egyptian hieroglyphs and Renaissance anatomical drawings, the study traces how artistic portrayals of teeth evolved into tools of both medical education and social hierarchy. Particular attention is given to the racialization of dental aesthetics, examining how caricatures, colonial pseudoscience, and exclusionary marketing practices contributed to enduring stereotypes and disparities in oral healthcare. Through the lens of cultural symbols like grills—once markers of status among Etruscans, …

Veracity Enhancement Using Non-Invasive Brain Stimulation: A Systematic Review, Alice Hou, Shahrukh Naseer, Abram Brummett

Posters

For decades, non-invasive brain stimulation (NIBS) techniques like Transcranial Magnetic Stimulation (TMS) and Transcranial directcurrent stimulation (tDCS) have been used in clinical settings as forms of neuromodulatory treatment for depression and other neurodivergent disorders. In recent years, there has been increased research in utilizing the non-invasive techniques to enhance cognition beyond one’s baseline, including language, memory, moral, and veracity enhancements. Due to the lack of systematic reviews in the growing field of veracity enhancement, we aim to provide a concise, summative overview of current research studying the impacts of NIBS on truthfulness, as well as its ethical dilemmas and future …

Identifying Novel Molecular Targets To Induce Ferroptosis In Drug-Tolerant Cancer Cells Through Computational Modeling, Haris J. Rana

Biological Sciences Undergraduate Honors Theses

Ferroptosis is an iron-dependent, reactive oxygen species (ROS)-driven form of regulated cell death in which the cell membrane is degraded by lipid peroxidation. It is regulated by multiple enzymes, such as glutathione peroxidase 4 (GPX4), which prevents membrane degradation by reducing lipid peroxides and protecting cells from oxidative damage. When inhibitors like RSL3 target GPX4, lipid peroxides build up, and toxic ROS compromises membrane integrity. Traditional anticancer treatments, such as most chemotherapies, aim to eliminate tumor cells by damaging DNA and triggering apoptosis. However, resistance to apoptosis is a “hallmark of cancer,” often resulting in treatment failure. As a distinct …

Wildly Inclusive: A Sensory Inclusive Initiative At The Memphis Zoo, Brianna Jernigan

Occupational Therapy Doctoral Capstones

The purpose of this doctoral capstone project is to address the need by applying occupational therapy principles to advance sensory inclusivity at the Memphis Zoo. Through the Wildly Inclusive program, efforts were created to foster a more supportive environment, encouraging meaningful participation and improving the quality of life for individuals with sensory processing differences.

Fostering Holistic Practice In The Outpatient Setting With Upper Extremity Impairment, Montanna Tapper

Occupational Therapy Doctoral Capstones

The purpose of the doctoral capstone project is to develop a program that improves psychosocial challenges faced by clients with upper extremity injuries or conditions. The program is designed to be implemented by occupational therapists in the outpatient setting and aims to increase holistic practice with this population by broadening focus past the physical impairment by addressing psychosocial factors.

Occupational Therapy For Older Adults Grieving Non-Death Loss, Zoe Sloas

Occupational Therapy Doctoral Capstones

An occupation-based grief support group was developed through literature review, enhancing therapeutic skills, and inter and intra professional collaboration through employing grief-specific occupational therapy interventions with the older adult population.

Use Cases For Art Therapy Intervention In Clinical Psychedelic Praxis, Kaitlin Maud

Expressive Therapies Capstone Theses

Psychedelic medicine has existed for thousands of years as a traditional, sacred practice and is now in varying stages of legalization for clinical application in the United States. Psychedelic-Assisted Therapy uses specific psychoactive substances to facilitate altered states of consciousness in which clients have access to unconscious material and there is a greater cognitive openness to new perspectives and possibilities. Art Therapy is a modality of psychotherapy with decades of data to support its clinical efficacy in treating mental illness and other chronic conditions. A review of the literature shows a range of use cases for art in the context …

Mechanisms Of Behavioral Change In Hosts Of Toxoplasma Gondii: A Review, Olivia Grimsley

Senior Honors Theses

The parasite Toxoplasma gondii is a highly ubiquitous parasite that latently infects an estimated 33% percent of the global population. Toxoplasmosis is of obvious clinical significance due to the extremely high risks to the unborn who contract it congenitally. Less attention has been given to a more subtle aspect of latent infection, which is the behavioral alterations that are commonly experienced by those who contract the parasite. Infected individuals commonly display a variety of altered behaviors, such as increased aggression and risk-seeking behaviors, depression, higher tendency towards suicide and self-directed violence, a loss of fear response, and a greatly increased …

Predicting Perinatal Mood Disorders, Honey Newton

Doctor of Nursing Practice

Perinatal Mood Disorders (PMD) constitute a significant public health concern, impacting the perinatal patient and the family.

Purpose

This project describes the relationship between Adverse Childhood Experiences and Perinatal Mood Disorders including depression and anxiety.

Goals

The goals of this study were to define the perinatal population in a rural Montana clinic and describe the relationship between ACEs and PMDs to identify early intervention opportunities.

Methods

A ten-year retrospective IRB approved study described the relationship between ACE, PHQ9 and OASIS scores to determine the prevalence of PMD and connection to ACE’s in perinatal patients in rural northwest Montana. Calculations were …

Himmelfarb Headlines - May/June 2025, The George Washington University, Himmelfarb Health Sciences Library

Himmelfarb Headlines (2009 - present)

News, information, and resources relating to Himmelfarb Library that is of interest to patrons.

Is The Price Of Organic Foods Worth The Potential Benefits To Your Health?, Jenna C. Warren

Undergraduate Honors Thesis Collection

What foods are healthier for you? This study will determine this based on where the food comes from, including the meat, dairy, and farming industries and how they treat animals and plants, and the nutrients these foods contain. From these findings, this study will choose foods for an average American’s three meals in a day for a organic and non-organic option. Then, it will compare the prices of a typical day’s worth of food and determine whether the price is worth the quality of food you are consuming.

The Interaction Between Phonological Reading Skills And Executive Functioning In Adults With Cochlear Implants, Tierney Marie Maurer

Undergraduate Honors Thesis Collection

Little research has been conducted concerning the interaction between phonological reading skills (the ability to recognize and manipulate the sounds of language) and executive functioning (a set of processes that are necessary for the cognitive control of behavior) in adults with hearing loss. The current study examined the potential association between phonological reading skills, hearing loss, and executive functioning in post-lingually deaf and hard of hearing adults who use cochlear implants. Two hypotheses were tested: 1) adult cochlear implant users have weaker executive functioning and phonological reading skills compared to their hearing peers; 2) adults with hearing loss who use …

Who’S In Control? Perceived Stress And Emotional Regulation Partially Mediate The Impact Of Adverse Childhood Experiences (Aces) On Mental Health And Life Satisfaction., Mary A. Burdan

Psychological Science Undergraduate Honors Theses

Adverse childhood experiences (ACEs) are potentially traumatic events that occur during the first 18 years of life and have a strong potential to negatively impact health and well-being in adulthood. The exploration of this connection is important because health and lifestyle behaviors have been linked to the leading causes of death in the United States. ACEs have been found to alter brain development and have been associated with mental health issues and lower life satisfaction, but information about the pathway between these connections is scarce. The present study aimed to investigate if inadequate emotional regulation and higher levels of perceived …

The Effects Of Starting Hormonal Contraceptive Use On Rumination, Abigail Brien

Psychological Science Undergraduate Honors Theses

Rumination, a cycle of repetitive dwelling on negative feelings and distress, is associated with mental health issues such as depression and anxiety. Although there is a substantial body of research on rumination and its association with depression and anxiety in women, there is a lack of studies specifically examining the role of hormonal fluctuation in this process. Changes in the menstrual cycle linked to estrogen and progesterone have been associated with mood regulation and susceptibility to depression, yet the impact of hormonal contraceptives (HCs) on rumination remains unexplored. The current study examined the role of HCs on rumination by comparing …

Culturally Concordant Dbt Steps-A Intervention In Orthodox Jewish Schools, Arielle Hershkovich-Elgavi

Theses, Dissertations and Culminating Projects

Existent research indicates that Dialectical Behavioral Therapy (DBT) is an efficacious treatment for mental health issues in many adult and adolescent populations, yet there is little research on the effect of DBT on culturally diverse, underserved populations (Mercado, & Hinojosa, 2017). Orthodox Jews are a culturally diverse, understudied, and underserved population (Schnall et al., 2014), that contends with strong stigmas against mental health treatment (Gearing et al., 2022). Orthodox Jewish community teachings are governed by religious values and precepts with a resistance to secular influence (Freund & Band-Winterstein, 2017). The social-emotional learning that is occasionally taught in some community schools …

Improving Brain Health: Exercise As A Tool For Enhancing Executive Function And Reducing Stress In Older African Americans, Destiny Ellise Ramos

Theses, Dissertations and Culminating Projects

Older African American (AA) adults face disproportionately higher risk of stress and Alzheimer's Disease and Related Dementias (ADRD) compared to other racial and ethnic groups, yet they remain underrepresented in intervention-based research. Previous research has suggested aerobic exercise may reduce stress and benefit executive functioning, which is among the first cognitive domains to be affected in ADRD; however, no studies to date have directly tested the impact of aerobic vs. non-aerobic exercise in older AAs at high risk for developing ADRD. The current study evaluated the effects of a group-based cardio dance fitness (CDF) exercise intervention versus a strength, flexibility, …

The Role Of Endogenous Estrogen In Effects Of Non-Invasive Brain Stimulation On Cognitive Performance, Samantha Walsh

Theses, Dissertations and Culminating Projects

High-definition transcranial direct current stimulation (HD-tDCS) directly modulates brain activity, allowing the study of brain-behavior relationships in cognitive processes. However, cognitive effects of tDCS vary widely, partly due to individual differences in baseline brain activity. Estrogen levels, which fluctuate during the menstrual cycle, are known to affect cortical excitability and impact neural response to tDCS, but no research to date has examined the potential moderating role of endogenous estrogen in tDCS effects on cognition. In this study, N = 16 healthy female adults completed four sessions of a working memory (WM) task while receiving tDCS (two active sessions, two sham) …

Advancing Drug-Drug Interaction Prediction Using Multi-Modal Feature Integration With Graph Neural Networks, Ernest C. Chianumba

Theses, Dissertations and Culminating Projects

Pharmaceutical treatments are essential for managing medical conditions, but drug-drug interactions (DDIs) pose significant risks to patient safety and healthcare outcomes. This research integrates Knowledge Graphs and Graph Neural Networks to predict DDIs by exploring complex drug relationships. We construct a comprehensive knowledge graph using DrugBank data (1,000 drugs, 155,774 interactions) enriched with molecular features from PubChem. Our methodology introduces a novel multi-modal approach by integrating transformer-based embeddings (ChemBERTa, SPECTER, and SBERT) to create 1152-dimensional feature vectors that capture structural, biomedical literature, and semantic properties of drugs. Formulating DDI prediction as a link prediction task, we compare three Graph Neural …

Igg4-Related Autoimmune Pancreatitis In Patients With Prior Occupational Exposure: A Case Report And Review Of Risks Concerning Blue-Collared Workers, Zachary A. Coren, Justin Le, Jason Tran, Nicholas Moscardelli, Krish Patel, Joshua Coren

Rowan-Virtua Research Day

Autoimmune pancreatitis (AIP), a manifestation of IgG4-related disease (IgG4-RD), is a rare, often misdiagnosed condition that can closely mimic pancreatic cancer, particularly in its clinical and radiographic presentation. We report the case of a 76-year-old retired plumber who presented with painless jaundice and was initially suspected to have pancreatic cancer based on imaging findings. Subsequent endoscopic evaluation, biopsy, and markedly elevated serum IgG4 levels led to a diagnosis of type 1 AIP. Treatment with corticosteroids resulted in rapid clinical improvement and reduction in IgG4 levels, confirming the diagnosis.

This case highlights the diagnostic challenges of AIP, especially among blue-collar workers …

Exploring The Role Of Lysine Acetylation During Biofilm Formation In Bacillus Subtilis, Jennifer Nguyen, Briana Ericka Reid, Valerie Carabetta

Rowan-Virtua Research Day

Biofilms are structured communities of bacterial cells encased in a self-produced extracellular matrix, composed of polysaccharides, extracellular DNA, and proteins. Bacteria in a biofilm pose significant challenges in healthcare due to their resistance to disinfectants and tolerance to antibiotics. In some species, histone-like proteins were found to be important structural components of the biofilm. Nε-Lysine acetylation is a widespread post-translational modification (PTM) in bacteria, which can alter a protein’s function. The histone-like protein HBsu in Bacillus subtilis is acetylated at seven sites in vivo. We hypothesized that the acetylation state of HBsu may alter biofilm structure or the genetic programming, …

Volatile Anesthetic Exposure During Organogenesis (Weeks 6-9): Implications For Fetal Brain Development, Cheryce Daniel, Kylon Coombs

Rowan-Virtua Research Day

Organogenesis, particularly during gestational weeks 6 through 9, represent a critical window for fetal brain development. During this period, neurogenesis, neural tube closure and synaptic organization are actively occurring. Disruption of these processes, especially from exogenous agents, can result in lasting developmental consequences.

The U.S Food and Drug Administration has issued warnings regarding the use of anesthetic agents such as isoflurane, sevoflurane, and desflurane. Noting the potential risk of neurotoxic effects on the developing brain. This warning is particularly highlighted when administered drugs are present for long periods of time or during repeated procedures. The goal of this literature review …

Dabigatran Reduced Acute Microgliosis In A Mouse Model With Tbi, Nicholas R. Eltman, Rashmeena Abbasi, Mary C. Kosciuk, Syed Ahmed, Jose L. Pascual, Randel L. Swanson, Nimish K. Acharya

Rowan-Virtua Research Day

Objective:

The study objective was to investigate the acute anti-inflammatory effects of dabigatran in a preclinical mouse controlled cortical impact (CCI) model of severe traumatic brain injury (TBI).

Design

Mice were separated into three groups: controlled cortical impact (CCI) with dabigatran (drug treatment, n=5), CCI with saline (positive control, n=5), and sham CCI without saline or dabigatran (negative control, n=3). Dabigatran (80mg/kg) or saline was administered orally at 2, 10, 18, 26, 34, and 42 hours following experimental CCI in the drug treatment or positive control groups, respectively. Animals in the negative control group received sham CCI only. 48h following …

Exploring Intracellular Signaling Responses To Ks18, A Potent Mcl-1 Inhibitor, In Multiple Myeloma, Emily Nelson, Omar S Al-Odat, Dhruti A. Brahmbhatt, Tulin Budak-Alpdogan, Subash Jonnalagadda, Manoj Kumar Pandey

Rowan-Virtua Research Day

Multiple myeloma (MM), a cancer of plasma B cells, is a hematological malignancy in which patients inevitably relapse and develop drug resistance. Mcl-1, a member of the anti-apoptotic subgroup of Bcl-2 family proteins, plays a critical role in the progression of multiple myeloma and contributes significantly to drug resistance. Elevated Mcl-1 expression is observed in approximately 52% of MM patients at diagnosis, increasing to 81% at relapse. Given its driving role in disease progression and therapy resistance, Mcl-1 inhibition has emerged as a promising therapeutic target, prompting ongoing research into the development and clinical evaluation of Mcl-1 inhibitors, particularly for …

What's In It For Me? The Benefits Of Breastfeeding For The Mother, Emily H. Mcmennamy

The Eleanor Mann School of Nursing Undergraduate Honors Theses

The purpose of this systematic review was to investigate both the short- and long-term benefits that breastfeeding has on maternal physical and mental health. The PICOT question was: In postpartum mothers, how does breastfeeding compared to formula and mixed feeding affect maternal physical and mental health, including outcomes in cardiovascular health, BMI, bleeding risk, and mental health both short term and long term? For this research, EBSCOhost and the National Library of Medicine databases were searched to find relevant studies and systematic reviews. Terms such as “breastfeeding and maternal health benefits,” “breastfeeding and postpartum health,” and “breastfeeding and weight loss” …

Indirect Cost Cap: Perspectives On Efficiency, Waste, And Equity, Neel B. Patel, Lakshman Segar

Rowan-Virtua Research Day

Background: On February 10, 2025, the NIH enacted a 15% cap on indirect costs, reallocating $4 billion from institutional overhead to direct research within a $35 billion funding framework. The policy follows longstanding concerns about unchecked growth and inefficiencies in indirect cost reimbursements, which rose from 15% in the 1950s to over 70% at some institutions by the 1990s. Notable examples include a $200 million overcharge at Stanford and millions in questionable expenditures identified in federal audits.

Objective: To evaluate the financial, operational, and equity-related impacts of the NIH’s indirect cost cap on U.S. research institutions.

Methods: …

Children Born To Mothers With Inflammatory Bowel Disease: A Review Of Pediatric Outcomes, Simran Gandhi, Kush Patel, Harmann Singh

Rowan-Virtua Research Day

Background: Inflammatory Bowel Disease (IBD), comprising Crohn’s disease and ulcerative colitis, frequently affects women during their reproductive years. While the impact of IBD on pregnancy has been widely studied, less is known about the long-term health outcomes in children born to affected mothers, particularly in the context of in utero exposure to immunosuppressive therapies.

Hypothesis: We hypothesize that children born to mothers with well-managed IBD experience normal growth and development, with minimal risk for immune-related complications, despite potential exposure to biologics and other IBD medications during gestation.

Methods: A literature review was conducted using PubMed and Google Scholar. Search terms …

Understanding Obesity Risk In Intellectual And Developmental Disabilities: Key Diagnoses And Factors, Elizabeth Kolaski, Wendy Aita, Jennifer Lecomte, Andrea Iannuzzelli

Rowan-Virtua Research Day

Background:

Individuals with intellectual and developmental disabilities (IDD) have obesity rates nearly twice those of the general population, leading to higher rates of diabetes, hypertension, sleep apnea, and reduced quality of life.¹ Genetic syndromes such as Prader-Willi syndrome (PWS) and conditions like autism spectrum disorder (ASD) and Down syndrome (DS) feature distinct mechanisms driving weight gain.² The burden of obesity in IDD exacerbates health disparities and strains caregivers and healthcare systems.³ Yet, comparative obesity prevalence and its drivers across specific IDD diagnoses remain poorly characterized.⁴

Hypothesis:

Obesity prevalence and underlying risk factors differ among IDD diagnoses …