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Intersection Of Pediatric Hypertension And Cardiovascular-Kidney-Metabolic Disease, Jessica O'Keeffe, Christina Kingshill, Jack Tompson, Andrew M. South, Carissa M. Baker-Smith

Department of Medicine Faculty Papers

PURPOSE OF REVIEW: The purpose of this review is to describe the intersection between pediatric hypertension and advancing stages of cardiovascular, kidney metabolic syndrome in children and adolescents.

RECENT FINDINGS: Cardiovascular-kidney-metabolic syndrome is highly prevalent in the pediatric population. The onset of CKM in childhood is influenced by the presence of antenatal risk factors such as maternal hypertensive disorders of pregnancy. Advancing stages of CKM in children and adolescents are strongly influenced by food insecurity and social determinants of health that impact the risk for childhood obesity. Activation of the renin-angiotensin-aldosterone system is a key mediator in the relationship between …

Reflections On Inclusive Qualitative Research With Autistic Emerging Adults: Lessons Learned And Practical Recommendations, Acadia W. Buro, Heidi Rishel Brakey, Monica F. Asencio Pimentel, Elizabeth Yakes Jimenez

Population Health Research and Scholarship

We explored inclusive qualitative data collection strategies for autistic emerging adults (ages 18–25) to identify nutrition-related resource needs and inform intervention development. We conducted Zoom interviews with autistic emerging adults, their caregivers, and service providers. We co-developed recruitment materials with a community advisory board of autistic advocates and offered and adapted interview accommodations in real time to align with participants’ preferences. Common accommodations included receiving questions in advance and in the chat, having a caregiver present, and simplifying questions. Some techniques used with neurotypical participants translated well to our participants, such as reflective listening, a conversational tone, and allowing pauses; …

Qualitative Evaluation Of The Seated Physical Activity Intervention (Spin) Randomized Controlled Trial For Wheelchair Users With Multiple Sclerosis (Ms): Formative Feedback And Future Directions, Angela J Piasecki, Robert W Motl, Katherine Froehlich-Grobe, Stephanie L Silveira

Faculty, Staff and Student Publications

Background/objectives: Wheelchair users with multiple sclerosis (MS) often face barriers that restrict participation in physical activity and exercise training. This manuscript reports on participant feedback to guide evaluating and refining a novel exercise training program, Seated Physical activity INtervention (SPIN). SPIN was adapted from the Guidelines for Exercise in MS (GEMS) approach using a three-step community-engaged research framework based on meeting the needs of wheelchair users with MS.

Methods: Semi-structured interviews were conducted with 9 participants who completed the 16-week SPIN intervention. The key SPIN intervention components were the exercise prescription, exercise equipment, and behavioral coaching grounded in Social Cognitive …

Evaluating The Reproducibility And Verifiability Of Nutrition Research: A Case Study Of Studies Assessing The Relationship Between Potatoes And Colorectal Cancer, Yasaman Jamshidi-Naeini, Colby J Vorland, Pranav Kapoor, Bailey Ortyl, Jocelyn Mineo, Luke Still, Korlu Sorsor, Shelby Rodney, Xander Tooze, Brent Flickinger, Beate Henschel, Stephanie L Dickinson, David B Allison

Faculty, Staff and Students Publications

The credibility of nutritional research is dependent on the rigor with which studies are conducted and the ability for independent assessment to be performed. Despite the importance of these, more work is needed in the field of nutrition to buttress the trustworthiness of nutrition research. To develop and apply a process for evaluating the rigor, reproducibility, and verifiability of nutritional research, using the relationship between potato consumption and Colorectal Cancer (CRC) as a case study. We updated existing systematic reviews to include studies on potatoes and CRC, assessing their design, execution, and reporting quality. We attempted to reproduce and verify …

Enhancing Sleep Quality Through Sleep Hygiene Education Among Adults In A Faith-Based Community, Denielle Earle-Thompson

Doctor of Nursing Practice Projects

Background

Adults between 18 and 64 years of age require at least seven hours of sleep per night; however, many adults do not meet this recommendation, contributing to increased risks for chronic disease, impaired functioning, mood disturbances, and reduced quality of life. Poor sleep quality has been associated with weakened immunity, cardiovascular disease, diabetes, obesity, anxiety, depression, and decreased daytime performance. Obtaining adequate, good-quality sleep is essential for maintaining overall health and well-being. In faith-based communities, combining health education with spiritual support may provide a holistic approach that addresses both physical and emotional contributors to poor sleep.

Purpose

The purpose …

The Transitional Liver Clinic: Study Protocol For A Stepped-Wedge Cluster Randomized Trial, Lindsay Yoder, Elliot B. Tapper, Richard S. Kalman, Mary Rinella, Nicole Bendin, Manisha Verma, Francis Pike, Naga Chalasani, Neha Nalumasu, Eric S. Orman

Einstein Health Papers

BACKGROUND: Patients with complications of advanced liver disease experience high rates of hospital readmission after discharge. Transitional care models have improved outcomes in other chronic conditions, but their efficacy in liver disease care remains uncertain. This randomized trial evaluates the effectiveness of a tailored transitional care model-the Transitional Liver Clinic (TLC)-in reducing readmissions, improving quality of life, and enhancing patient satisfaction for patients with advanced liver disease.

METHODS: This is a 45-month, stepped-wedge cluster randomized trial enrolling up to 1000 patients with advanced liver disease across 4 academic medical centers. Each site transitions from usual care to the TLC intervention …

Artificial Intelligence In Hospital Pharmacy Practice: Effectiveness, Internal Validity, And Translational Readiness: A Systematic Review, Kwanchai Rattanamanee, Parnupong Kiewsiri, Prayuth Poowaruttanawiwit

The Thai Journal of Pharmaceutical Sciences

Background: Artificial intelligence (AI) is increasingly integrated into hospital pharmacy, offering potential to enhance medication safety, therapeutic decision-making, and operational efficiency. However, the internal validity and translational readiness of current interventions remain uncertain.
Objectives: The objective of the study was to systematically review AI applications in hospital pharmacy and evaluate their effectiveness, internal validity, and readiness for clinical integration.
Methods: Following Preferred Reporting Items for Systematic reviews and Meta-Analyses 2020 guidelines and PROSPERO registration (CRD420251067936), We systematically searched PubMed, Embase, Scopus, Web of Science, IEEE Xplore, and ThaiJO (2000–June 2025). for randomized controlled trials (RCTs), cohort, quasi-experimental, and case–control studies …

Contribution Of Animals To Biomedical Advancements In The Current Era: A Narrative Review, Leena Rajathy Port Louis, Mani Rajarathinam, Prithiviraj Nagarajan, Divya Sekar, Nisha Perumal

The Thai Journal of Pharmaceutical Sciences

Animal research has played a major role in the development of vaccinations and therapies for illnesses such as tetanus, polio, meningitis, hepatitis, and Severe Acute Respiratory Syndrome Coronavirus 2. For every prescription drug available today, animal testing and research have contributed immensely. This narrative review aims to explore the contribution of animals to biomedical advancements in the current era, which involved a search of peer-reviewed literature using electronic databases such as Scopus, Web of Science, and PubMed. In current biomedical research, animals help develop new treatments for long-term illnesses such as cancer, HIV, and Alzheimer’s. Animals also aid in the …

Epidemiology And Outcomes Of Geriatric Trauma At Uab, Lindy Reynolds

ETDs from 2020-2029

Adults over the age of 65 are the fastest growing portion of the population and account for a growing percentage of the trauma patient volume at trauma centers around the country. Older adults experience longer length of stays, higher mortality and complication rates than their younger counterparts. As a result, there has recently been an increased focus on models of geriatric trauma care, one of which is the addition of geriatric medicine consults for older trauma patients. The primary objectives of this dissertation were to examine the effect of the consult policy on outcomes using an interrupted time series approach, …

A Retrospective Analysis Of Dental Needs Identified By Intraoral Videography In Elderly Patients With Mild To Moderate Dementia In Long-Term Care Facilities: Feasibility Of A Novel Screening Mechanism For Oral Health, Kevin Hahn

ETDs from 2020-2029

This retrospective analysis explores the viability of employing intraoral videography to identify dental needs among long-term care (LTC) facility residents with cognitive impairment and/or mild to moderate dementia. Inadequate oral hygiene in these individuals can lead to dental plaque buildup, oral dysbiosis, gingivitis, dental caries, and periodontitis. Such conditions can impact both oral and systemic health. However, delivering oral hygiene in LTC facilities faces challenges due to care-resistant behavior triggered during mouth care. And many individuals in residential LTC facilities do not have access to dental care outside of severe emergencies due to cost, reimbursement patterns, lack of access to …

Individual Responsibility And The Limits Of U.S. Dietary Guidelines: Addressing Ultra-Processed Food Consumption Through Structural Policy, Malika Al Kattan, Lynne Alexandra Kennedy

All Works

No abstract provided.

Bone Marrow Adiposity, Obesity, And Tumor Burden In Newly Diagnosed Multiple Myeloma, Ananya Deshpande

ETDs from 2020-2029

Multiple Myeloma (MM) is the second most common hematologic malignancy in the United States. It is characterized by the accumulation of clonally expanded plasma cells in the bone marrow, which leads to end organ damage and myeloma-defining events requiring treatment. The only modifiable risk factor for MM is obesity. However, associations between obesity, bone marrow adipocytes, and tumor burden at MM diagnosis remain unclear. We evaluated associations of bone marrow adipocytes, body mass index (BMI), and clinical features of tumor burden among 168 patients with histologically confirmed newly diagnosed multiple myeloma (NDMM) enrolled in the Integrative Molecular and Genetic Epidemiology …

Independent Living Skills For The Aging Population Of Adults With Disabilities, Sara K. Fetter Otd, Otr, Jennifer L. Martin Otd, Otr, Cht, Clt, Michele L. Mccarroll Phd, Faacvpr, Acsm-Ccep, Ccrp, Lssbb

Developmental Disabilities Network Journal

Adults with intellectual disability (ID) are living longer and increasingly outlive family caregivers. Strengthening independent living and vocational skills has therefore become a critical public-health priority. Occupational therapy (OT) can address this need through person-centered, community-based programming. This paper describes the co-design, delivery, and preliminary outcomes of a short occupation-based curriculum intended to enhance autonomy and work readiness in aging adults with ID. In partnership with a Dallas, Texas nonprofit, the authors conducted a needs assessment and created an 8-session course rooted in the Independent Living Model and the Occupational Competence Model. The curriculum addressed four domains (physical health, financial …

Hypovitaminosis A - Associated Neurologic Syndrome With Concurrent Babesiosis In A Captive African Lion Cub (Panthera Leo), Kano, Nigeria, Shaarani Habibu Musa, Aminu Bello Hanga, Auwal Usman Nagoma, Caleb Ayuba Kudi, Paul Ayuba Abdu, Musa Ibrahim Waziri, Haruna Baba Galadima, Yusuf Aminu Yusuf, Muhammed Mikail

The Thai Journal of Veterinary Medicine

Neurological disorders in captive wild felids presents diagnostic and therapeutic challenges, particularly in juveniles animals maintained under suboptimal nutritional transitions. This case report describes the synergistic effects of dietary deficiencies and a concurrent hemoparasitic infection in a seven-month-old male African lion cub (Panthera leo) weighing 30 kg, housed at Audu Bako Zoological Garden in Kano, Nigeria. Following premature weaning onto an unsupplemented muscle-meat diet, the cub exhibited progressive neurological symptoms, including ataxia, hindlimb paresis, star-gazing, and opisthotonos. Hematological analysis revealed a mild normocytic, normochromic anemia (packed cell volume; 23%) and the presence of erythrocytes rouleaux formation, while Giemsa-stained …

Psycho-Behavioral And Psychosocial Factors Influencing Childhood Obesity In The United States, Nadia Ntori Nkansah

Walden Dissertations and Doctoral Studies

No abstract provided.

Breaking Bread And Barriers: Interprofessional Strategies To Improve Mental And Nutritional Health In Family Caregivers, Candy Ratliff

The Journal of the Research Association of Minority Professors

Family caregivers provide essential unpaid support to individuals with chronic illness, disability, dementia, and age-related decline; however, caregiving responsibilities often place caregivers at increased risk for psychological, physical, nutritional, and social challenges. This literature review examines the mental health and nutritional implications of family caregiving and explores barriers that contribute to declining caregiver wellness. Findings reveal elevated rates of depression, anxiety, emotional exhaustion, social isolation, food insecurity, sleep disturbances, financial strain, and chronic stress among caregivers. The literature further highlights the interconnected relationship between mental health, nutrition, and overall quality of life. Given the multidimensional nature of caregiver burden, interprofessional …

Design And Development Of Foot Arch Diagnosis Application, Arif Wicaksono, Arta Farmawati, Neni Trilusiana Rahmawati, Herianto Herianto

Folia Medica Indonesiana

The foot is a part of the lower extremity that has several characteristics, namely foot length, width, height, and arch. Foot arch is a characteristic that has not been widely researched in Indonesia, but it plays a crucial role in movement and daily life. A normal foot arch facilitates physical activities, work, and overall human health, whereas an abnormal foot arch can hinder physical activities, work, and negatively affect health. Foot-arch diagnosis is commonly performed using footprint creation and foot-arch determination. Foot arch diagnosis can be established through conventional examinations, which are relatively more time-consuming, and examinations using scanning devices, …

Differences In The Effects Of Multicomponent Vivifrail Training And Senam Lansia On Physical Performance And Fall Risk In Pre-Frail Elderly, Nadia Ovianti, Annisa Susilowati, Endang Ambarwati, Robby Tjandra Kartadinata, Tanti Ajoe Kesoema, Erna Setiawati

Folia Medica Indonesiana

Pre-frailty is a condition where individuals experience early signs of frailty. Frailty is a geriatric syndrome associated with falls and reduced physical performance, which will impact the health and well-being of the elderly population. To mitigate the harmful effects, the WHO recommends Vivifrail, a multicomponent exercise that is effective in preventing frailty. In Indonesia, the most common program for the elderly community is Senam Lansia (elderly exercise). No studies have compared the effects of these two exercises on the pre-frail elderly community. This study aims to assess differences between Vivifrail training and Senam Lansia on physical performance and fall risk, …

Effectiveness Of Cadre Training In Improving Knowledge On The Completion Of The Elderly Health Book In Sidoarjo, Lilik Djuari, Sulistiawati Sulistiawati, Linda Dewanti, Muhammad Izhar Yuliantama, De Farras King, Minarni Wartiningsih

Folia Medica Indonesiana

Primary healthcare in Indonesia faces challenges due to an ageing population since 2021. An elderly health book, published by Ministry of health, is an essential tool for recording, monitoring, and following up elderly health status. However, Health cadres have not yet fully understood how to fill in and use the book, resulting in suboptimal data quality. The objective of this study was to evaluate the effectiveness of cadre training to complete the Elderly Health Book (before and after training) in Sidoarjo Regency. A quasi-experimental study with a one-group pre-test and post-test design was conducted among 50 elderly health cadres which …

The Readiness Reset: Sleep, Stress, And Pain Management For Tactical Performance, Lauren Fried

Tactical & Occupational Performance Conference

Tactical professionals operate in high-demand environments where sleep disruption, chronic stress, and persistent pain are often normalized, but these factors significantly affect readiness, resilience, and long-term performance. This session explores how sleep, stress, and pain interact at the physiological and neurological levels to influence decision-making, recovery, injury risk, and operational effectiveness in first responders and military personnel.

Participants will gain a deeper understanding of how nervous system regulation, circadian rhythms, and pain perception affect both physical and cognitive performance under stress. Drawing on current research and applied human performance principles, this session highlights practical, field-applicable strategies that tactical professionals and …

Comprehensive Geriatric Assessment Identifies Multidimensional Vulnerabilities In Older Adults With Heart Failure, Ci̇han Kiliç, Rengi̇n Demi̇r, Özlem Yilmaz Aykent, Zerri̇n Yi̇ği̇t, Pinar Küçükdağli, Banu Özulu Türkmen, Güli̇stan Bahat, Mehmet Aki̇f Karan

Turkish Journal of Medical Sciences

Background/aim: Heart failure (HF) in older adults is frequently accompanied by geriatric syndromes that remain unrecognized in conventional cardiac evaluations. The vulnerabilities of older adults with and without HF in terms of muscle strength, physical performance, functional capacity, frailty, nutritional status, cognition, mood, anxiety, polypharmacy, and comorbidity were investigated using comprehensive geriatric assessment (CGA).

Materials and methods: A cross-sectional study was conducted in two academic outpatient clinics, enrolling 420 adults aged ≥60 years, including 92 (21.9%) with HF. Data included sociodemographic characteristics, anthropometric measurements, and CGA parameters: handgrip strength, the Five-Times Sit-to-Stand Test (FTSST), the Short Physical Performance Battery (SPPB), …

Urinary Dkk3 As A Predictor Of Ckd Stages In Reflux Nephropathy In Children, Ayşe Seda Pinarbaşi, Nesli̇han Günay, İnayet Güntürk, Di̇dem Barlak Keti̇, Si̇bel Yel, Sekure Rabi̇a Ulueren, Cevat Yazici, Muammer Hakan Poyrazoğlu, İsmai̇l Dursun

Turkish Journal of Medical Sciences

Background/aim: Reflux nephropathy is an important cause of chronic kidney disease (CKD) in children. The search for new biomarkers continues, as early intervention is important to slow the progression of CKD. Urinary Dickkopf-3 (uDKK3), a potential marker of tubulointerstitial fibrosis, has been studied in adults but not extensively in children with CKD. This study was conducted to determine the role of uDKK3 levels in predicting the CKD stage in children with reflux nephropathy.

Materials and methods: This cross-sectional study included 113 children with CKD stages 1–4 with reflux nephropathy and 28 healthy controls. uDKK3 concentrations were measured using enzyme-linked immunosorbent …

Association Of Vitamin D, Oxidative Stress Markers, And Hormonal Factors With Male Infertility: A Case-Control Study In Pakistan, Muhammad Tayyab Ihsan, Ayesha Ali Malick, Sher Khan, Sher Khan, Muhammad Tahir Khan, Haq Nawaz Khan, Rehana Rehman

Turkish Journal of Medical Sciences

Background/aim: Infertility impacts around 15% of couples worldwide, with male factors accounting for approximately 50% of cases. Despite this significant share, male infertility remains understudied, particularly in developing nations such as Pakistan. The present study explores the association between male infertility and seminal plasma concentrations of oxidative stress markers, inhibin B, and vitamin D, along with their relationship with sperm parameters.

Materials and methods: The dataset of the study consisted of seminal plasma levels from 30 fertile and 60 infertile males. Total antioxidant capacity (TAC), Vitamin D, malondialdehyde (MDA), 4-hydroxynonenal (4-HNE), lipid peroxide (LPO), superoxide dismutase (SOD), and inhibin B …

Omega-3–Rich Fish Oil Lipid Emulsions Significantly Prevent Sepsis-Driven Mesenteric Hypoperfusion And Multi-Organ Injury In Murine Models, Gökşen Öz, Esi̇n Özçelebi̇, Ayşe Yeşi̇m Göçmen, Cenk Sükmensüer, Selma Yildirim, Arzu Topeli̇, Alper Bektaş İski̇t

Turkish Journal of Medical Sciences

Background/aim: Parenteral feeding is used in critically ill patients when enteral nutrition is inadequate or intolerable, and the gastrointestinal tract is not functioning properly. Lipid emulsions play a major role in parenteral nutrition because they supply necessary fatty acids and a high-calorie density. We investigated the effects of parenteral lipid emulsions on mesenteric perfusion, inflammation-induced oxidation, and organ damage in lipopolysaccharide-induced mice endotoxemia model.

Materials and methods: In septic mice, organ damage induced by lipopolysaccharide was assessed by histopathology and biochemical examination. Additionally, an ultrasonic blood flowmeter was used to measure the impact of lipid emulsions on mesenteric blood flow. …

An International Multidisciplinary Consensus Statement On Laparoscopic Liver Biopsy, Si Yi Lei, Yu Han, Don C. Rockey, Khalid Alswat, Vincent Wai Sun Wong, Nozim Jumaev, Carlos Jesus Toro-Huamanchumo, Safwan Taha, Mohamed El-Kassas, Jacob George, Mark Muthiah, Omar Ghanem, Masato Yoneda, Dao Viet Hang, Giada Sebastiani, George Papatheodoridis, Adam Abu-Abeid, Andrew G. Robertson, Sang Hyun Kim, Rudolf Weiner, Kamal Mahawar, Asim Shabbir, Mohammad Kermansaravi, Reynu Rajan, Yosuke Seki, Halit Eren Taskin, Scott Shikora, Edward Oliveros, Chetan Parmar, Qiuye Cheng, Omar Thaher, Elena Ruiz-Úcar, Rodolfo Oviedo, Rui Ribeiro, Mario Musella, Almino C. Ramos, Seung-Wan Ryu, Tamer Abdelbaki, Wei Jei Lee, Man Pan Chan, Jose Eduardo Garcia Flores, James Skinovsky, Ahmad Madkhali, Sylvia Weiner, Frank Tacke, Wah Yang, James Neuberger, Ming-Hua Zheng

Research outputs 2022 to 2026

Laparoscopic liver biopsy (LLB) provides a way to obtain liver tissue samples under direct visual inspection of the liver surface. It complements percutaneous liver biopsy (PLB) for complex or high-risk cases where PLB cannot be performed. Clinical practices for LLB vary across centers due to the lack of international standards. To improve the procedural quality and diagnostic efficiency of LLB, a multidisciplinary panel of 45 international experts from 6 continents, including hepatology, hepatobiliary surgery, gastrointestinal surgery, and metabolic and bariatric surgery, developed this consensus statement through three rounds of a modified Delphi process. This consensus covers clinical application scenarios, high-risk …

Pa Dent J March 2024

Pennsylvania Dental Journal

The Pennsylvania Dental Journal is produced by the Pennsylvania Dental Association six times a year, in January, March, May, July, September and November. Issues include regular columns with regional news impacting the Pennsylvania membership including editorial and government relations news, association activities, member updates, continuing education opportunities, and classifieds.

Pa Dent J Jan 2024

Pennsylvania Dental Journal

The Pennsylvania Dental Journal is produced by the Pennsylvania Dental Association six times a year, in January, March, May, July, September and November. Issues include regular columns with regional news impacting the Pennsylvania membership including editorial and government relations news, association activities, member updates, continuing education opportunities, and classifieds.

Pa Dent J Jul 2022

Pennsylvania Dental Journal

The Pennsylvania Dental Journal is produced by the Pennsylvania Dental Association six times a year, in January, March, May, July, September and November. Issues include regular columns with regional news impacting the Pennsylvania membership including editorial and government relations news, association activities, member updates, continuing education opportunities, and classifieds.

Pa Dent J Sept 2024

Pennsylvania Dental Journal

The Pennsylvania Dental Journal is produced by the Pennsylvania Dental Association six times a year, in January, March, May, July, September and November. Issues include regular columns with regional news impacting the Pennsylvania membership including editorial and government relations news, association activities, member updates, continuing education opportunities, and classifieds.

Simulation Using Aspiration Screening Tool And Bolus Testing For Graduate Nutrition And Dietetics Students, Kendrea Garand, Tracy Maluchnik, Trisha A. Cousins, Jonathan Beall, James Coyle

Teaching and Learning in Communication Sciences & Disorders

Utilization of simulation is increasing during pre-professional training of allied health disciplines, including speech-language pathology and nutrition/dietetics programs. The impact on student learning using simulation in the areas of dysphagia assessment and management has begun to emerge. The purpose of this study was to explore learning outcomes of 21 students enrolled in a Nutrition and Dietetics graduate program prior to and after didactic and hands-on application learning experiences, including employment of an aspiration screening tool and modification of food/liquid textures. The didactic and practical portions were led by speech-language pathology faculty. A pre- and post-test was analyzed to determine change …