Digital Commons Network^™

Tackling Social Stigma: An Ethical Obligation In Healthcare Intervention To Involuntary Childlessness, Persis Naumann

Electronic Theses and Dissertations

The stigma associated with involuntary childlessness has negatively affected health and well-being for several decades. This situation is particularly exacerbated for women within the Tamil socio-cultural context, resulting in feelings of shame, neglect, denial, isolation, and constituting a significant barrier to long-term access to healthcare services. Although advancements have been made in the provision of biomedical care, the psychosocial support remains inadequately addressed. Moreover, there are currently no healthcare interventions that specifically target the stigma associated with this issue, which hinders open communication with healthcare providers, delays necessary treatments, and adversely impacts overall health outcomes. The central thesis of this …

The Underdiagnosis: Addressing The Underdiagnosis Of The Female Athlete Triad And Relative Energy Deficiency In Sport, Nicholas R. Bohannon, Kayla E. Hasty, Stacie Fairley, Robert Walker

Research Day

Introduction: Many elite athletes train their whole lives to reach elite status. For another set of athletes, their sports careers were cut short for one reason or another. The underdiagnosing of the Female Athlete Triad (Triad) or Relative Energy Deficiency in Sport (RED-S) might be the reason for some athletes. A few main barriers have prevented the medical community from accurately diagnosing athletes suffering from the Triad and RED-S.

Objective: This study investigates the critical barriers to early and accurate detection of the Triad and RED-S. Key obstacles include insufficient research, limited physician education, and inadequate awareness among athletes and …

Podcasts In Mental, Physical, Or Combined Health Interventions For Adults: Scoping Review, Elizabeth M. Dascombe, Philip J. Morgan, Ryan J. Drew, Casey P. Regan, Gabrielle Turner-Mcgrievy, Myles D. Young

Faculty Publications

Background:

The increasing prevalence of poor mental and physical health in adults is a global health concern. Given the scope of this problem, scalable and effective treatment interventions are needed. While podcasts (online digital audio files) are becoming more popular, the extent of podcast use in mental, physical, or combined health interventions has not been reviewed.

Objective:

This scoping review primarily aims to summarize the available evidence regarding the use of podcasts in health promotion interventions. A series of 5 research questions was designed to systematically review and accurately represent podcast use in current research interventions.

Methods:

We conducted a …

Characterising Acute And Chronic Care Needs: Insights From The Global Burden Of Disease Study 2019, A. A. Asadi-Pooya

Department of Neurology Faculty Papers

Chronic care manages long-term, progressive conditions, while acute care addresses short-term conditions. Chronic conditions increasingly strain health systems, which are often unprepared for these demands. This study examines the burden of conditions requiring acute versus chronic care, including sequelae. Conditions and sequelae from the Global Burden of Diseases Study 2019 were classified into acute or chronic care categories. Data were analysed by age, sex, and socio-demographic index, presenting total numbers and contributions to burden metrics such as Disability-Adjusted Life Years (DALYs), Years Lived with Disability (YLD), and Years of Life Lost (YLL). Approximately 68% of DALYs were attributed to chronic …

A Honduran Prevalence Study On Soil-Transmitted Helminths Highlights Serological Antibodies To Tm-Wap49 As A Diagnostic Marker For Exposure To Human Trichuriasis, Neima Briggs, Leroy Versteeg, Rojelio Mejia, Jeroen Pollet, Maria Jose Villar, Bin Zhan, Graeme Segal, Stephanie Novak, Patricia Lenihan, Paul Musgrave, Viviana Ellis, Carol Florencia Coello, K Jagannadha Sastry, Joe Craft, Peter J Hotez, Maria Elena Bottazzi

Faculty, Staff and Student Publications

Soil-transmitted helminth (STH) infections rank among the most prevalent communicable diseases of humans, yet detection of these parasites is mostly restricted to identifying active infection through fecal examinations. Currently, there are no commercial diagnostic tools to identify a prior whipworm or hookworm exposure, and the few serological assays for roundworm infection have not been well validated for crossreactivity or infections in humans. Such diagnostic restrictions limit the range of scientific and clinical questions that surround STH exposures and their implicated relationship to chronic diseases, such as autoimmunity, allergy, and cancer. The goal of this investigation was to evaluate the diagnostic …

Social Determinants Of Health In Patients With Diabetes Mellitus Ii, Iman N. Ashraf, Donald Penney

Research Day

Introduction: More than 37 million people in the United States have diabetes, the majority 90-95% with type 2 diabetes. The social determinants of health (SDH) are the non-medical factors that influence health outcomes. They are the conditions in which people are born, grow, work, live, and age, and the wider set of forces and systems shaping the conditions of daily life. These forces and systems include economic policies and systems, development agendas, social norms, social policies and political systems. The SDH have an important influence on health inequities - the unfair and avoidable differences in health status seen within and …

A Prehabilitation Protocol For The Asymptomatic, Newly Diagnosed, Stage Iv Colon Cancer Patient., Scott Salters, Kaitlyn Wright, Sumana Moole

Research Day

Introduction

Prehabilitation is defined as the process of optimizing a patient’s health prior to a medical or surgical intervention. Although this is an emerging concept and is not yet standard of care, literature has shown prehabilitation to be a potentially useful tool in medicine. In the field of gastroenterology, it has been primarily used for patients undergoing surgery to remove cancers. We want to utilize prehabilitation and apply it towards patients that are awaiting oncological treatment for asymptomatic, advanced gastrointestinal malignancies. This case report highlights the need for a specific prehabilitation protocol in these scenarios and discusses evidence-based recommendations based …

Perforated Duodenal Ulcer In A Patient With Multiple Endocrine Neoplasia Type 1: A Case Report, Ahad Y. Khatri, Andrew A. Kramer

Research Day

Introduction: Multiple Endocrine Neoplasia Type 1 (MEN1) is a hereditary syndrome characterized by tumors of the parathyroid, pancreas, and pituitary gland. Among its gastrointestinal manifestations, gastrinomas are particularly concerning due to their association with Zollinger-Ellison syndrome (ZES), which leads to excessive gastric acid secretion and peptic ulcer disease (PUD). These symptom overlaps can lead to misdiagnosis of MEN1 as peptic ulcer disease and gastroenteritis. Additionally, while ulcers are a well-recognized consequence of gastrinomas and MEN1, perforation remains a rare but life-threatening complication.

Case Presentation: A 36-year-old female initially presented with diffuse abdominal pain, nausea, vomiting, and diarrhea. She had a …

Sculpting Healing Spaces: Bridging The Gaps In Cancer Care Facilities, Mayra B. Mendez

Bachelor of Architecture Theses - 5th Year

Healthcare environments become a vital component in patient outcomes, particularly in Cancer Care Facilities, where the emotional and physical requirements of treatment are profound. Exploring how the reconsideration of cancer care facilities can reshape the patient’s experience and improve the healing outcomes. Traditional clinical spaces, often sterile and impersonal, can increase patient stress, anxiety, and discomfort. Cancer care facilities in the Atlanta region are struggling to meet the demands of modern cancer treatment due to architectural limitations such as overcrowded spaces, inefficient layouts, and a lack of patient-centered environments. How can the integration and experience of Biophilic Design Principles bridge …

Cardiovascular Health In The Transition From Adolescence To Emerging Adulthood: A Scientific Statement From The American Heart Association, Jewel Scott Phd, Rn, Fnp-C, Anandita Agarwala, Carissa M. Baker-Smith, Matthew J. Feinstein, Karen Jakubowski, Jill Kaar, Niyati Parekh, Kershaw V. Patel, Janna Stephens

Faculty Publications

Cardiovascular disease remains a leading cause of death in the United States, with an alarming rise in the proportion of young adults experiencing cardiovascular events. Many adolescents enter adulthood with significant cardiovascular disease risk factors. This scientific statement addresses the critical need for cardiovascular health promotion during emerging adulthood, a transitional stage between the ages of 18 and 25 or 29 years of age. We discuss the significance of social determinants of health and the interplay between individual-level risk factors and developmental changes, including shifts in substance use, social connections, and emotional well-being. We conclude by outlining strategies for optimizing …

Effect Of Rehabilitation Exercises And Antioxidants On Patients With Stable Heart Failure, Shimaa Mohamed Abu Zeid, Walid A. Ali

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences

The research aims to find out the effect of rehabilitation exercises and antioxidants in some physical and physiological abilities, free radicals and the degree of pain for patients with stable heart failure, and the research sample was selected randomly and whose ages ranged between 40–45 years and their number is 30 female patients with this disease, and the researcher used the experimental approach as the most appropriate approach to solve the research problem, as the sample was divided into two groups equal in number, each of which (15) patients (experimental and control), and the tribal tests were carried out after …

Assessing The Effectiveness Of A Nurse-Led Family-Focused Program On The Physical Health Domain Of Children With Congenital Heart Defects, Maha Abdul Hussein Mutasher Al-Barki, Wameedh Hamid Shaker Alzubeidi

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences

Background: Assessing the effectiveness of a nurse-led family-focused program on the physical health domain of children with congenital heart defects (CHDs) is a critical area of research. CHDs are among the most common congenital anomalies, affecting nearly 1 in 100 live births. physical activity plays an important role in overall health and recovery congenital heart disease. Quality of life educational include specific directions to increase level of physical activity, such as walking daily or exercising regularly. Objectives: This study aims to assess the effectiveness of a nurse-led family-focused program in improving the physical health outcomes of children with CHDs. Methods …

Evaluation Of Rbc Indices And Significance Of Mentzer Index For Differentiation Between Iron Deficiency Anemia And Beta Thalassemia Trait, Raghda Hameed Jasim, Rasha Hussain Aouda

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences

Background: Anemia is a global public health problem affecting developed and adversely affecting developing countries. About 1.62 billion peoples are affected worldwide, currently pregnant women are the most vulnerable population corresponding to 24.8%. Objective: To evaluate RBC indices and significance of Mentzer index for differentiation between Iron deficiency anemia and Beta thalassemia trait. Patients and methods: Cross sectional study was conducted in Babylon Maternity and Pediatrics Teaching Hospital for a period of 4 months. Data was collected prospectively after approval of the research proposal was gained, the study involved 114 patients that were referred to the Babylon Maternity and Pediatrics …

Can Anemia Be A Prognostic Indicator To Scope For Gastroesophageal Junction Adenocarcinoma?, Ryan Tam, Neha Narayanan, Evan Basha, Joel Thompson

Advances in Clinical Medical Research and Healthcare Delivery

Gastroesophageal junction adenocarcinoma is a rapidly progressive disease that has a poor prognosis with a 5-year survival rate of 20%. It commonly presents with major symptoms of dysphagia and weight loss in addition to a long-standing history of reflux. As of now, screening for esophageal adenocarcinoma (EAC) is dependent on identifying risk factors which include a family history of Barrett’s esophagus and esophageal adenocarcinoma or patients with gastroesophageal reflux disease and at least one other risk factory for EAC such as age greater than 50 years, obesity or central adiposity, history of smoking, or male gender. Here, we present a …

Iron Deficiency—More Than Just Anemia: A Literature Review, Arianna S Moss, Zahra Pakbaz

Journal of Community Hospital Internal Medicine Perspectives

Iron deficiency (ID) is a global public health concern, as it can be a prodrome of gastrointestinal (GI) malignancies, exacerbate chronic conditions, and lead to an overall decreased quality of life. Despite being the most prevalent nutritional deficiency, it remains underdiagnosed by many healthcare professionals. Misconceptions regarding the clinical and laboratory manifestations of ID lead to delayed or missed diagnoses, contributing to poor patient outcomes. Though anemia is a commonly known consequence of ID, there are additional consequences that remain underrecognized by the medical community, including vague signs and symptoms, such as fatigue, depression, and abnormalities in white blood cell …

Rescue Of The First Mitochondrial Membrane Carrier, The Mpic, By Tat-Mediated Protein Replacement Treatment, Samar Zabit, Orly Melloul, Michal Lichtenstein, Erin L. Seifert, Haya Lorberboum-Galski

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

The mitochondrial phosphate carrier (mPiC), encoded by the nuclear gene SLC25A3, is synthesized with an N-terminus mitochondrial targeting sequence (MTS), enabling its import into the mitochondria. mPiC imports inorganic phosphate (P_i) into the mitochondrial matrix for ATP production and other matrix phosphorylation reactions, as well as regulates mitochondrial Ca²⁺ uptake and buffering of matrix Ca²⁺. PiC also imports copper (Cu), crucial to COX subunit holoenzyme assembly. Variants in SLC25A3 exist and lead to mPiC deficiency (MPCD), cause a rare autosomal recessive disease with no current cure; patients with MPCD usually die within the first …

Experience Of Coparents/Partners Of African American Mothers Participating In Breastfeeding Education, Samantha Hickson

Walden Dissertations and Doctoral Studies

Coparents and partners of African American mothers are critical in the initiation and continuation of breastfeeding and influence a woman’s decision to breastfeed. The purpose of this qualitative study was to explore the experience of coparents/partners of African American mothers participating in breastfeeding education and its impact on the support they provide. Bandura’s social cognitive theory provided the theoretical foundation for this study. Data were collected via semi-structured interviews with 11 participants. Data analysis followed the traditional seven steps of interpretative phenomenological analysis. Findings showed that while coparents and partners of African American breastfeeding mothers found breastfeeding education to be …

Eos Wellness Center: Rethinking Inpatient Mental Health Facility Design, Emily Simms

Bachelor of Architecture Theses - 5th Year

The design of mental health facilities significantly impacts patient outcomes, especially for individuals with depression. Environmental factors such as lighting, thermal comfort, and access to nature influence mental health. This research explores how architectural design can reduce self-harm incidents and enhance recovery outcomes for patients with depression. The project hypothesizes that synchronizing light patterns and thermal comfort with patients’ circadian rhythms will reduce self-harm incidents and improve recovery. The problem established in the research is that disruptions to circadian rhythms increase the risk of depression, PTSD, and anxiety by 30% (Burns et al., 2022). Suicide is also the second leading …

Protocol For A Randomized Controlled Trial To Determine If Biomarkers Predict Response To A Pediatric Chronic Pain Symptom Management Program, Rona L Levy, Tasha B Murphy, Margaret M Heitkemper, Miranda A L Van Tilburg, Ann R Mcmeans, Jocelyn Chang, Cynthia Boutte, Katherine Lamparyk, Bruno P Chumpitazi, Robert J Shulman

Faculty, Staff and Students Publications

Background/Objectives: Disorders of gut-brain interaction (DGBI), characterized by chronic abdominal pain and significant disability, affect 15-20% of children and adults and continue into adulthood in ~60% of cases. Costs for adults reach USD 30 billion per year, yet effective management strategies are elusive. Studies support using cognitive behavioral therapy (CBT), but abdominal pain only improves in ~40% of patients. Dietary management (low FODMAP diet; LFD) has also shown promise but it is effective in only a similar percentage of patients. Studies suggest that biologic factors (biomarkers) contribute to CBT response. Similarly, gut microbiome composition appears to influence abdominal pain …

Protocol For A Randomized Controlled Trial To Determine If Biomarkers Predict Response To A Pediatric Chronic Pain Symptom Management Program, Rona L Levy, Tasha B Murphy, Margaret M Heitkemper, Miranda A L Van Tilburg, Ann R Mcmeans, Jocelyn Chang, Cynthia Boutte, Katherine Lamparyk, Bruno P Chumpitazi, Robert J Shulman

Children’s Nutrition Research Center Staff Publications

Background/Objectives: Disorders of gut-brain interaction (DGBI), characterized by chronic abdominal pain and significant disability, affect 15-20% of children and adults and continue into adulthood in ~60% of cases. Costs for adults reach USD 30 billion per year, yet effective management strategies are elusive. Studies support using cognitive behavioral therapy (CBT), but abdominal pain only improves in ~40% of patients. Dietary management (low FODMAP diet; LFD) has also shown promise but it is effective in only a similar percentage of patients. Studies suggest that biologic factors (biomarkers) contribute to CBT response. Similarly, gut microbiome composition appears to influence abdominal pain …

Enhancing Nurse Competency: Proper Application Of Chlorhexidine Gluconate Dressings To Prevent Central Line Associated Bloodstream Infections, Joseph Earich

Doctor of Nursing Practice Scholarly Projects

Central line-associated bloodstream infections (CLABSIs) pose a significant risk to patient safety and healthcare outcomes. The proposed Doctor of Nursing Practice (DNP) project addresses the knowledge gap among nurses regarding the correct procedures for changing chlorhexidine gluconate (CHG) dressings on central lines. The goal is to enhance nurse education and adherence to best practices, thereby reducing the incidence of CLABSIs. The project employs a quasi-experimental design with a pre-test and post-test methodology. Nurses will complete a pre-test to assess their baseline knowledge of CHG dressing changes. The nurse will participate in a hands-on educational session to improve their understanding and …

A Multicomponent Quality Improvement Initiative For The Early Identification, Prevention, And Management Of Delirium In The Medical-Surgical Setting, Sarah K. West

Doctor of Nursing Practice Scholarly Projects

Hospital-acquired delirium affects older adult patients, across the healthcare continuum. The incidence in frail older adults is high, costly, and often deemed preventable. Hospital-acquired delirium is associated with a multitude of short- and long-term complications, resulting in an increased rate of morbidity and mortality. The challenges of early recognition and management are prevalent in healthcare literature. While published guidelines exist, hospital systems continue to struggle with the standardization of geriatric delirium care. Given medical-surgical nursing is the cornerstone of hospital care, it is imperative to establish a standardized delirium prevention and management guideline, at this level of care, to optimize …

Diabetes Self-Management Education For Older Adults In Primary Care, Makilah Rae Furlan

Doctor of Nursing Practice Scholarly Projects

Type 2 Diabetes (T2DM) is a chronic disease that impacts 27.2 million seniors 65 and older. Evidence-based care for T2DM includes a combination of medication and disease-management behaviors. Access to education to teach patients healthy behaviors to manage their disease is limited and even less accessible to geriatric patients with aging learning needs. The scholarly project addresses this gap in patient education by implementing evidence-based diabetes self-management education for geriatric patients to increase patient knowledge and confidence in implementing self-management behaviors. The scholarly project aims to assess health behaviors in patients aged 65 and older with established type 2 diabetes …

Final Scholarly Project: Enhanced Recovery After Surgery (Eras) Guidelines For Pancreaticoduodenectomies, Rebecca Wheeler

Doctor of Nursing Practice Scholarly Projects

A pancreaticoduodenectomy, or Whipple procedure, is the only curative option for pancreatic cancer. For those eligible for tumor resection, the Whipple procedure is a difficult surgery for both the patient and provider. Complications following pancreaticoduodenectomy are numerous and include infection, delayed gastric emptying, high hospital costs, and pancreatic fistulas. Enhanced Recovery After Surgery (ERAS) protocols exist to provide evidence supporting standardization of practices that lead to the improvement of these patient outcomes. An ERAS protocol for the pancreaticoduodenectomy, first established in 2012, is inconsistently implemented in healthcare facilities. Researchers collected data involving the use of the Whipple procedure ERAS guidelines …

In A Healthy D-Iii Population, Is Blood Flow Restriction More Effective For Increasing Quadriceps Strength Compared To Concentric Resistance Training?, Conner R. Ruff

Masters Theses/Capstone Projects

Strength is an important factor in the prevention of injuries. However, strength can decrease for numerous reasons, such as age, chronic injuries, or acute injuries. In recent years, Blood flow restriction (BFR) has been used as a modality to increase a patient’s strength gain while utilizing a low load of weight. However, in most research, BFR has been used concurrently with conventional strength training or compared to concentric training in the treatment of an injured population. This study looked at the effect of BFR on a healthy Division III (DIII) collegiate student population and its effectiveness in increasing quadriceps strength …

The Effectiveness Of Telehealth For The Management Of Chronic Disease, Mariam Odunewu-Smith

Honors Capstones

Telehealth made a wide appearance in the medical industry during the Covid-19 pandemic due to the necessary decrease of physical interaction. It has continued to thrive and populate more patients since then. The benefits of telemedicine include quick, reliable one-onone sessions with a healthcare provider virtually, and is overall less costly compared to in person visits. Seeing a medical provider online is helpful in aiding patient recovery and management of chronic diseases. It is used to significantly improve the quality of life in the patients seen today. A literature review was conducted using databases such as PubMed and ScienceDirect. Papers …

Enhancing Postoperative Care For Vascular Patients: Pre- And Post-Test Clinical Knowledge Acquisition Of Early Mobilization Education For Interventional Healthcare Providers, Jennifer Wenger

Doctor of Nursing Practice Scholarly Projects

Peripheral vascular disease (PVD) is a chronic, systemic condition that often requires surgical intervention, presenting significant postoperative risks, including complications like thromboembolisms, pneumonia, and delayed functional recovery. Evidence-based practices (EBP), particularly early mobilization guidelines, have proven to improve recovery outcomes but remain inconsistently applied among interventional healthcare providers. The project addresses this critical issue by evaluating the impact of structured educational sessions on interventional healthcare providers’ knowledge and application of mobilization guidelines in postoperative vascular care. Using the John Hopkins Model of Evidence-Based Practice, a quasi-experimental design was adopted to assess the impact of the education. The project includes pre- …

Analysis Of Clinical Outcomes And Cost Effectiveness Of Neuromuscular Blocking Drug Reversal In Patients Classified As Obese, Trevor Mack

Doctor of Nursing Practice Scholarly Projects

Obesity predisposes patients to heightened risks of adverse outcomes following surgery, including residual neuromuscular blockade and postoperative complications. The administration of non-depolarizing neuromuscular agents (NMBAs) is fundamental for muscle relaxation and optimal surgical conditions. However, the subsequent reversal of these blockers with agents like sugammadex or neostigmine is crucial to mitigate these risks. While sugammadex is recognized as a clinically superior choice due to its rapid and more complete reversal, its extensive use is often limited by cost, presenting challenges in obese patients who already face increased susceptibility to complications. This project evaluates the cost-effectiveness of sugammadex versus neostigmine in …

Examination Of Eating Disorder Risks And Body Image Dissatisfaction Among Division Iii Student-Athletes, Maddie Wisener

Masters Theses/Capstone Projects

Eating disorders (ED) and pathogenic behaviors are prevalent concerns among collegiate athletes due to performance pressures and body image expectations. This cross-sectional study examined the risk of ED among 243 student-athletes (Males: 54.9%, Females: 44.3%, Non-Binary: 0.4%) at a private institution in the Midwest. The convenience sample included student-athletes from baseball, basketball, cheerleading, cross country, football, golf, lacrosse, soccer, softball, tennis, track, volleyball, and wrestling teams. The participants were given a demographic survey, the Eating Attitudes Test-26, and Sex-Specific Figural Stimuli Silhouettes to assess eating behaviors and perceived and desired body images. Overall, 22.1% of participants were at risk for …

Development Of A Clinical Pathway For Acute Pain Management As An Element Of The Prevention Of Delirium In Older Adult Trauma Surgery Patients, Stacey Mermigos

Doctoral Scholarly Projects & Capstones

For hospitalized patients, delirium is prevalent and associated with poor outcomes including increased mortality, morbidity, hospital length of stay, and healthcare costs. Although past studies have identified effective interventions to both prevent and manage delirium in critically ill patients, the most widely used evidence is not easily generalized to non-critically ill patients, specifically trauma patients who experience acute pain, serial surgical procedures, and other notable precipitating and predisposing factors. Clinical pathways are structured plans that are useful for encouraging consistent, evidence-based interventions for various medical conditions and situations. At this time, there is no clinical pathway for the prevention of …