Digital Commons Network^™

Co-Design And Pilot Testing Of A Nurse-Led Gp-Supported Self-Management Intervention For Breast Cancer Survivors With Cardiovascular Diseases: A Study Protocol, Anu Correya, Jing Yu Tan, Xian Liang Liu, Daniel Bressington, Leah East, Tao Wang

Research outputs 2022 to 2026

Background/Objectives: Self-management intervention strategies are recommended to address the needs of breast cancer survivors (BCSs) who have cardiovascular diseases (CVDs). Despite the benefits, these strategies are often suboptimally implemented, resulting in inadequate cardiovascular management among BCS with CVDs. The project aims to develop a nurse-led and GP-supported self-management (NGPS) intervention to reduce cardiovascular risks in BCS with CVDs and evaluate its feasibility and potential effects in primary care settings using the double diamond co-design process and the Medical Research Council (MRC) Framework for Developing and Evaluating Complex Interventions.

Methods: The study will be conducted in two phases. In phase I, …

The Effect Of Cyp1a2 Gene Polymorphisms On Caffeine Pharmacokinetics And Exercise Performance In Male Recreational Athletes, Chloe Masters, Ajmol Ali, Claire Badenhorst, Martin Dickens, Kay Rutherfurd-Markwick

Research outputs 2022 to 2026

This study examined the effects of caffeine consumption on endurance exercise performance, and the influence of CYP1A2 gene polymorphisms in caffeine pharmacokinetics and exercise performance. The data sets of two randomised, double blind, placebo-controlled crossover study design experiments have been merged. Thirty-eight recreationally active male participants provided saliva samples for CYP1A2 genotyping (AA homozygotes n = 19; AC heterozygotes n = 19) and completed either a 10-km run or 40-km cycling time trial of 60-min following a single dose of 6 mg·kg⁻¹ caffeine (CAF) or placebo (maltodextrin; PLA) throughout which heart rate (HR) and time to completion (TTC) were …

The Effects Of Anti-Parkinsonian Medications On Bone Mineral Density: A Systematic Review, Mícheál Ó Breasail, Motaz B. El-Leissy, Karan P. Singh, Matthew Smith, Jakub Mesinovic, Marc Sim, Andrew Evans, David Blacker, Saman Heshmat, Neil Mahant, Christian Girgis, Peter R. Ebeling, Ayse Zengin

Research outputs 2022 to 2026

IntroductionParkinson's disease (PD) is associated with elevated fracture risk, particularly at the hip. Antiparkinsonian medications have also been associated with increased fracture risk; although their direct effects on bone mineral density (BMD) remains unclear.ObjectiveInvestigate whether antiparkinsonian medications influence BMD.MethodsA systematic search of four databases (Embase, MEDLINE, APA PsycINFO, Web of Science) was conducted up to 24/11/2025 using terms related to PD, antiparkinsonian medications and bone.ResultsA total of 748 records were identified, with 543 screened following deduplication. Fourteen studies underwent full-text review, of which seven met inclusion criteria. Three studies assessed bone mineral content or surrogate measures at non-standard sites (hand …

Sagittal Abdominal Diameter And Abdominal Aortic Calcification Are Associated With Incident Major Adverse Cardiovascular Events: The Manitoba Bone Density Registry, Haftom N. Abraha, Abadi K. Gebre, Marc Sim, Cassandra Smith, Syed Zulqarnain Gilani, Zaid Ilyas, Fatima Zarzour, John T. Schousboe, Lisa M. Lix, Neil Binkley, Siobhan Reid, Barret A. Monchka, Douglas Kimelman, Joshua R. Lewis, William D. Leslie

Research outputs 2022 to 2026

BackgroundSagittal abdominal diameter (SAD), a measure of visceral adiposity, has been linked to major adverse cardiovascular events (MACE). However, the relationship between SAD and abdominal aortic calcification (AAC), a marker of subclinical vascular disease, and whether they independently and jointly predict MACE remains unclear.ObjectiveTo investigate whether weight-normalized SAD and AAC scored using a validated machine learning algorithm (ML-AAC24) are independently and jointly associated with incident MACE.MethodsSAD and ML-AAC24 were measured from dual-energy X-ray absorptiometry (DXA) posteroanterior and lateral spine images, respectively, from the Manitoba Bone Density registry.ResultsAmong 8806 individuals (mean age 75.1 ± 6.6 years, 93.9% women), 11.3% experienced MACE …

Effects Of Obstructive Sleep Apnea On Circulating Immune Cells Profiles: Evidence From Nhanes Dataset And Mendelian Randomization, Yajie Jia, Xiang Gao, Shenglong Xu, Jingli Shi, Haifeng Hou, Yanru Li, Demin Han

Research outputs 2022 to 2026

Objectives: This study aimed to investigate the impact of Obstructive Sleep Apnea (OSA) on immune cell profiles by utilizing both the National Health and Nutrition Examination Survey (NHANES) dataset and a two-sample Mendelian Randomization (MR) method. Methods: We included 20,732 participants from the NHANES to explore the relationship between symptom defined OSA and peripheral immune cells. Additionally, we conducted a two-sample MR analysis to investigate the effect of OSA on 35 summarized peripheral immune cell properties and 731 immunophenotypes. To ensure the robustness of findings in MR analysis, we conducted a sensitivity analysis. Results: The NHANES dataset and MR analysis …

Longitudinal And Cross-Sectional Evidence That Daily Resting And Activity Energy Expenditures Are Independent In Humans, Andrew K Yegian, Elizabeth Pachus, Leanne M Redman, Steven B Heymsfield, K Falkenhain, Alexandra R Harris, Shaji K Chacko, William W Wong, Daniel E Lieberman

Faculty, Staff and Students Publications

Total energy expenditure (TEE) is commonly modelled as the sum of resting energy expenditure (REE), activity energy expenditure (AEE), and diet-induced thermogenesis (DIT). This additive model has recently been challenged by the constrained energy balance model, which proposes that reductions in mass-adjusted REE compensate to some extent for increases in AEE, rendering mass-adjusted TEE effectively invariant. We tested these competing models using two complementary approaches. First, we conducted a short-term longitudinal, repeated-measures experiment in 12 adults who completed 10-day periods of high and low physical activity separated by a washout period. TEE was measured with doubly labelled water, AEE with …

Comprehensive Assessment Of Direct And Passive Smoking Across The Pancreatitis Spectrum, Samuel Han, Dhiraj Yadav, Jun Xu, Melena D Bellin, William E Fisher, Evan L Fogel, Chris Forsmark, Phil A Hart, Liang Li, Stephen J Pandol, Walter G Park, Guru Trikudanathan, Stephen K Van Den Eeden, Santhi Swaroop Vege, Darwin L Conwell, Christie Y Jeon, Consortium For The Study Of Chronic Pancreatitis, Diabetes, And Pancreatic Cancer (Cpdpc)

Faculty, Staff and Students Publications

Objectives: Smoking is a key risk factor for pancreatitis, contributing to pathogenesis and disease progression. Data regarding second-hand smoking, or passive smoking (PS) exposure, are lacking. We therefore aimed to assess the impact of PS exposure across the pancreatitis spectrum.

Methods: We analyzed baseline data from the PROCEED study, a multicenter study in the United States including patients with acute (AP), recurrent acute (RAP), and chronic (CP) pancreatitis. Participants detailed their individual smoking history and PS exposure, which was compared between AP, RAP, and CP subgroups. Participant factors and clinical characteristics were compared by level of individual and PS exposure. …

Reclassifying Pediatric Nafld Using The Steatotic Liver Disease Framework: A Multicenter Retrospective Study From The Nash Crn, Tin Bo Nicholas Lam, Katherine P Yates, Sheila L Noon, Kimberly P Newton, Mark H Fishbein, Jean P Molleston, Stavra A Xanthakos, Ajay K Jain, Miriam B Vos, Niviann M Blondet, Krupa R Mysore, Cynthia A Behling, Laura A Wilson, Jeffrey B Schwimmer

Faculty, Staff and Students Publications

Background and aims: The terminology for hepatic steatosis and NAFLD was revised under the umbrella of steatotic liver disease, with metabolic dysfunction-associated steatotic liver disease (MASLD) as the primary subtype. MASLD is defined by hepatic steatosis plus at least 1 cardiometabolic risk factor. A new category, Met-ALD, describes MASLD with alcohol consumption below the defined thresholds for alcohol-associated liver disease (ALD). While adult studies have demonstrated strong concordance between NAFLD and MASLD, the applicability of this framework in children remains unclear.

Approach and results: We assessed children clinically diagnosed with NAFLD and enrolled in the NASH CRN who had available …

Nuclear-Specific Reductive Carboxylation Of Alpha-Ketoglutarate Fuels Histone Acetylation To Induce Chromatin Accessibility And Gene Activation, Abhisha Sawant Dessai, Nadya A Elhalawany, Tao Dai, Justine J Jacobi, Christian Prechtl, Alphonse N Dimeck, Sierra R Morton, Mark D Long, Prashant K Singh, Nagireddy Putluri, Mariana Lopes, Song Liu, Dominic J Smiraglia, Katerina V Gurova, Peder J Lund, Leah A Gates, Sung Yun Jung, Subhamoy Dasgupta

Faculty, Staff and Students Publications

Mitochondria remain at the core of cell metabolism, whereas the nucleus integrates cellular and environmental signals to activate genes. However, the mechanisms that directly link cellular metabolism to gene regulation are not well understood. Here we show, a metabolic pathway in the nucleus controls acetylation of histones by nuclear localization of mitochondrial enzymes aconitase (ACO2) and isocitrate dehydrogenase (IDH2). Metabolic tracing studies show that IDH2 and ACO2 catalyze reductive carboxylation of α-ketoglutarate to rapidly synthesize citrate to increase nuclear acetyl-CoA pool. Genetic and proteomic analyses reveal nuclear IDH2 and ACO2 form a complex with KAT2A/GCN5 for acetylation of histones to …

Determinants Of Early Mortality After Congenital Heart Surgery: A 7-Year Single-Center Experience In Saudi Arabia, Saud Abdulaziz Bahaidarah, Jowana Mahmoud Aljinaid, Amal Ahmad Alzahrani, Jana Mohammad Banjer, Lujain Abdulsalam Kofiyah, Nesmah Amin Noaman, Rahaf Adel Badkook, Raghad Abdulaziz Aljabri, Raghad Saeed Alghamdi, Renad Mohammed Alamoudi, Sarah Salem Bawazir, Gaser Abdelmohsen Abdelmohsen

Journal of the Saudi Heart Association

Objectives:

To determine predictors of early mortality among pediatric patients undergoing congenital heart surgery at a tertiary care center in Saudi Arabia.

Methods:

This retrospective cohort study included 955 pediatric patients who underwent congenital heart surgery at King Abdulaziz University Hospital, Jeddah, between January 2017 and December 2023. Demographic, clinical, operative, and postoperative variables were collected.

Results:

Overall mortality was 4.9%. Mortality was higher among neonates and infants and among patients with RACHS categories 4–6. Non-survivors had longer cardiopulmonary bypass times and more frequent delayed chest closure. Postoperative complications, including the need for extracorporeal membrane oxygenation (ECMO), depressed cardiac function, …

Incidence Of Post-Ercp Pancreatitis Among Solid-Organ Transplant Recipients: A Retrospective Cohort Study, Josh Warner

Graduate Medical Education Research Journal

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Rising Enzymes: The Hepatic Fallout Of Refeeding Syndrome, Emma Sheridan

Graduate Medical Education Research Journal

NA

Saag Calculation Inconsistent With Cause Of Ascites: A Case Report, Sammy Woller

Graduate Medical Education Research Journal

NA

Colorectal Cancer Risk In Microscopic Colitis And Eosinophilic Colitis: A Retrospective Analysis, Emma Sheridan

Graduate Medical Education Research Journal

NA

Facilitating Living Kidney Donation: Retrospective Evaluation Of Weight Loss Interventions To Support Kidney Donation, Julia Dumitrescu, Roslyn Mannon, Scott Westphal, Ashley Brabec, Regina Rau, Amy Olsen, Taylor Cidlik

Graduate Medical Education Research Journal

Background. Living kidney donor transplantation provides recipients with kidney failure with an excellent graft function and survival. Donation of a kidney entails a thorough medical and psychosocial evaluation. Obesity is an increasingly prevalent medical condition and a known risk factor for the development of chronic kidney disease post-donation. Accepting overweight and obese individuals as living kidney donors remains controversial. The purpose of this study was to review the impact of obesity on the determination of candidates for living kidney donation at a single transplant center.

Methods. We performed a retrospective chart review of living kidney donors evaluated over 5 …

Exercise-Induced Gene Expression Profiles In Adults With Obesity: A Systematic Review Of Molecular Adaptation, Brandon Galvan, Luis Alberto Flores, Flor Isela Torres-Rojo, Natanael Cervantes-Hernández, Cinthia Verónica Villegas-Balderrama, Liliana Aracely Enríquez-Del-Castillo

Baltic Journal of Health and Physical Activity

Background: Obesity is a multifactorial and chronic condition characterized by excess adiposity and systemic low-grade inflammation. Exercise exerts metabolic and anti-inflammatory effects partly mediated through gene expression modulation in skeletal muscle and adipose tissue. However, heterogeneous responses among obese individuals suggest that genetic and epigenetic mechanisms shape exercise adaptation. Objective: This systematic review aimed to identify the genes and molecular pathways modulated by physical exercise in adults with obesity, and to classify them according to their biological functions across different exercise modalities. Methods: Following PRISMA guidelines, randomized controlled trials were searched in PubMed, SpringerLink, Science Direct, Cochrane, LILACS, Web of …

Navigating Complex Esophageal Perforations: A Case-Specific Approach To Successful Outcomes, Harsimran Kalsi, Anushree Rai, Kobina Essilfie-Quaye, Neeka Akhavan, Yaseen Perbtani, Tony S. Brar

HCA Healthcare Journal of Medicine

Esophageal perforation is a life-threatening condition requiring prompt diagnosis and effective management. While self-expanding metal stents (SEMS) are a first-line treatment, persistent leaks often necessitate adjunctive endoscopic interventions. A structured, multimodal approach is critical for optimizing outcomes and avoiding surgical intervention. A 44-year-old man developed an iatrogenic esophageal perforation following surgical leiomyoma enucleation. Initial treatment with overlapping fully covered self-expanding metal stents (FC-SEMS) failed to achieve closure, necessitating endoscopic suturing for defect reinforcement. Despite suturing, persistent leakage required placement of a larger-diameter FC-SEMS, secured with an endoscopic fixation system to prevent migration. Serial imaging confirmed successful defect closure, allowing the …

Trends In Emergency Department Utilization After Metabolic And Bariatric Surgery In The United States, Andrew Sanders, Isabella Moncada, Sabrina Avanzato, Michelle Fakler, Michael Dombek, R. Wesley Vosburg

HCA Healthcare Journal of Medicine

Background

In this article, we sought to understand the factors associated with emergency department (ED) utilization by patients after metabolic and bariatric surgery (MBS). The hopes were that modifiable risk factors could be identified to reduce ED visits after MBS.

Methods

We analyzed data from the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program database (MBSAQIP) which is comprised of data from all nationally accredited bariatric centers in the United States. For our study, we included a population of 681 743 patients having undergone the 2 most common MBS procedures: sleeve gastrectomy (SG) and gastric bypass (GBP). Using logistic …

Are Combat Athletes Different Sleepers? A Pittsburgh Sleep Quality Index-Based Comparative Survey Across Athletic Populations, Zofia Tkocz, Małgorzata Hołda Dr, Michał Spieszny, Adam Zając, Robert Trybulski, Aleksandra Filip-Stachnik

Baltic Journal of Health and Physical Activity

Background: Sleep plays an important role in athletic performance, recovery, and cognitive function. The aim of this study was to compare sleep quality and selected sleep-related  variables in combat sports athletes and athletes from other sport disciplines . Materials and Methods: Ninety-eight competitive athletes participated in the study, including 52 combat sports athletes and 46 athletes  representing other sport disciplines. Sleep quality was assessed using the modified Pittsburgh Sleep Quality Index (PSQI) with a weekly recall period, global PSQI score and additional  variables, such as sleep duration, sleep latency, and habitual sleep-wake times, were analyzed using general linear models adjusted …

Exploring The Role Of Circulating Mir-21 As A Potential Biomarker For Celiac Disease In Pediatric Patients, Shaymaa M. Jabbar, Manal M. Khadhim

Al-Qadisiyah Medical Journal

Background: This training explored the possibility of circulating miR-21 as a biomarker for celiac illness (CD) in pediatric patients. The demographic and clinical characteristics were compared between groups. A case-control design was employed with 45 pediatric CD patients and 45 healthy controls. Aim: The present training stayed directed to exploring the expression of circulating miRNAs in those sick with celiac disease—three miRNAs—miR-21-3p. Methods: Blood samples were collected from participants, and RNA was isolated. miR-21 expression was quantified using STEM-LOOP RT-qPCR. Demographic data (age, gender, residence) and clinical features (family history, disease duration, symptoms) were collected. Serological tests for CD diagnosis …

The Relationship Between Access To Basic Safe Drinking Water And Under-Five Mortality In Indonesia: An Ecological Study, Jasmin Jadevra Fezantino, Raquel Amanda Salmasari, Hanania Carrisa, Zahra Annisaa Hudaya

Jurnal Nasional Kesehatan Lingkungan Global

Infant mortality remains a worrying public health issue, particularly in areas with poor access to drinking water and sanitation. In 2020, Papua Province recorded an infant mortality rate of 49.04 per 1,000 live births and West Papua 47.23. These figures are far above the national average. This study aims to determine the relationship between access to safe drinking water and infant mortality rates in provinces in Indonesia. This study used an ecological design with secondary data from the 2023 Indonesian Health Survey and the 2023 Directorate of Public Health. The analysis was descriptive and followed by a Spearman correlation test. …

Factors Affecting The Incidence Of Stunting In Sawangan Subdistrict, Depok City, In 2023, Amanda Salsabila, Shaumi Maghfira Lamakampali, Erin Shafa Jasmine, Vera Putri Pranoto, Ratu Ayu Dewi Sartika, Primasti Nuryandari Putri

Jurnal Nasional Kesehatan Lingkungan Global

Stunting remains a major problem in Indonesia, particularly in Depok City, West Java. This study aims to analyze the factors influencing stunting in Sawangan District. The study design used is a cross-sectional study, analyzing test variables such as stunting incidence, maternal characteristics (age, education, maternal nutritional status during pregnancy, and personal hygiene), and toddler factors (exclusive breastfeeding status and LBW incidence) using univariate, bivariate (chi-square test), and multivariate (binary logistic regression) analyses. The analysis shows that maternal personal hygiene and LBW incidence in toddlers significantly influence stunting incidence. Other factors, such as age, education, and maternal nutritional status during pregnancy, …

Association Between Cooking Fuel Type And The Incidence Of Acute Respiratory Infections In Toddlers In Indonesia: A Cross-Sectional Study Based On 2017 Sdki Data, Ghina Puspa, Meiravigliosi Hermawan, Nuha Rafida Yumna

Jurnal Nasional Kesehatan Lingkungan Global

Acute Respiratory Tract Infection (ARI) remains a major health problem among toddlers in Indonesia and is closely related to exposure to indoor air pollution. This study aims to analyze the relationship between the type of cooking fuel used by households and the incidence of ARI in toddlers in Indonesia. The study used a cross-sectional design based on data from the 2017 Indonesian Demographic and Health Survey. The study sample included 196,804 respondents who met the inclusion criteria, namely having complete information on the type of cooking fuel and ARI symptoms. The independent variable was the type of cooking fuel divided …

Socio-Demographic And Clinical Profile Of Diabetic Patients: A Cross-Sectional Study, Ali Kadhim Obyes, Suhair Mohammed Hassoon, Dhakam Mohammed Abbas

Al-Esraa University College Journal for Medical Sciences

Background: Diabetes mellitus is a growing global health crisis, disproportionately affecting low- and middle-income countries. In Iraq, prevalence is estimated at 12–15%, yet comprehensive local data on patient profiles remain scarce. Objectives: To describe the socio-demographic, clinical, nutritional, and laboratory profile of diabetic patients attending a tertiary hospital in Babylon, Iraq. Patients and Methods: A hospital-based cross-sectional study was conducted among 200 adult diabetic patients (type 1 or type 2) admitted to the endocrinology unit of Marjan Teaching Hospital from December 2025 to May 2026. Data were collected via face-to-face interviews, medical records, and laboratory reports. Descriptive statistics (frequencies, percentages, …

Cleft Lip And Palate: From Genetic Foundations To Psychological Impact – A Multidisciplinary Review, Farah Abdulwahab Al-Saadi, Teeba Fares Hadi, Sura Saleem Albermani

Al-Esraa University College Journal for Medical Sciences

Cleft lip and/or cleft palate consider one of the most known and common congenital disorders of the head causing clear disruption of the normal face structure. Despite being the most seen birth defects, the clefts genetic basis is still not fully comprehended. Clefts have sporadic genetic nature, it can occur duo to rare mutations as part of syndromic disease or it can be isolated, non-syndromic cleft. The contemporary advances in genomic technology have enabled a deeper comprehension of the complex architecture of cleft lip/palate, of these technologies are genome-wide association studies, whole genome sequencing, transcriptome-wide association studies and others. Furthermore, …

Clinical Interactions Of Celiac Disease And Relationship With Type 1 And Type 2 Diabetes Mellitus, Noor Thair Tahir, Raghda Shams Akram, Aseel Ibrahim Abbas, Sahar Abdul Wahab Alshaban, Fatma Abd Alhamza Obed

Al-Esraa University College Journal for Medical Sciences

Celiac disease is a typical autoimmune ailment that can be brought on by gluten, a protein present in wheat, barley, and rye. It is estimated that one person out of every 100 worldwide has celiac disease, with the majority going untreated. Although it can manifest asymptomatically, celiac disease is typified by a variety of gastrointestinal and extra-intestinal symptoms. The consistency of clinical, serological, and histopathological data is essential for the diagnosis of celiac disease. The diagnosis, nevertheless, is often missed and can be difficult. A higher risk of complications and a negative impact on quality of life are linked to …

Comprehensive Evaluation Of The Severity And Contributing Factors Of Anemia Among Pregnant Women Attending Bab Al-Mouadum Primary Health Care Center, Baghdad, Iraq, Fatema Aouda Abbas, Enass Razzaq Hamza, Israa. M. Ali Alameen

Al-Esraa University College Journal for Medical Sciences

Background : Anaemia is one of the famous disorders which spreading between women during pregnancy and considered one of the risks that surround both mother and foetus, this phenomena is more common in developing countries. Methods : The aim of this study is to evaluate haemoglobin (Hb) levels and detect the other related risks in 200 pregnant women, the study done in healthcare centre in Bab Al-Mouadum, Baghdad Al Iraq, The data were collected in period between 15 October and 15 November 2023. By using questionnaire and interview, the statistical analyses is done by expert, and its including descriptive statistics …

Prevalence And Determinants Of Metabolic Syndrome Among Adults Attending Primary Health Care Centers In Baghdad: A Cross-Sectional Study, Muammar Basheer Yasir, Almottesembellah Abdalruhman Gaiz, Noor Abdulredha Jaleel

Al-Esraa University College Journal for Medical Sciences

Metabolic syndrome has emerged as an important health concern globally, especially in developing countries where urbanization and lifestyle changes are rapidly increasing. No reliable epidemiological information regarding the prevalence and risk factors associated with metabolic syndrome is available among Iraqi adults in primary health care (PHC) clinics. This study was designed to determine the prevalence rate of metabolic syndrome and identify potential risk factors among adults attending PHC centers in Baghdad. Methods: An analytical cross-sectional study design was used, targeting 412 adult subjects selected randomly from multiple PHC centers in Baghdad. Sociodemographic, lifestyle, anthropometric, and biochemical data were collected. The …

The Association Between Osteoporosis In Females Following Menopause And Vitamin D Deficiency, Hadel Kareem Al-Rubaiawi, Noor Adel Hussein, Dunia Abdul Jabbar Star, Amer Hasan Abdullah, Salma Abdul-Ridha Abbas, Hawazin Aziz Hamim

Al-Esraa University College Journal for Medical Sciences

The intricate relationship among osteoporosis, vitamin D deficiency, and hormonal changes. Growth hormone, cortisol, parathyroid hormone, estrogen, testosterone, thyroid hormones, and thyroid hormones are a few of the hormones that affect bone turnover and density. Alterations in their concentrations, whether brought on by healthy aging or illnesses, can interfere with bone remodelling and increase the risk of osteoporosis. Moreover, inadequate levels of vitamin D increase the risk by decreasing the absorption of calcium and the mineralization of bone. Estrogen and vitamin D deficits increase bone loss, especially in postmenopausal women. Proactive treatment techniques, including hormone replacement therapy, vitamin D supplements, …

Analysis Of Priority Vaccine-Preventable Diseases Using The Paho-Adapted Hanlon Method In Bogor City In 2024, Sonia Annisa Br Ketaren, Tri Yunis Miko Wahyono, Bai Kusnadi

Jurnal Epidemiologi Kesehatan Indonesia

Vaccine-preventable diseases (VPDs) remain a major public health challenge despite substantial progress in immunization programs. In Indonesia, routine immunization coverage has shown a post-pandemic recovery trend; however, disparities in access to health services and surveillance quality persist across regions. This study aimed to determine priority VPD problems in Bogor City and identify factors contributing to the highest-ranked disease. A mixed-methods study was conducted in Bogor City from October 2024 to January 2025. Quantitative prioritization was performed using the Pan American Health Organization (PAHO)-adapted Hanlon method across eight VPDs. Qualitative data were collected through in-depth interviews with key informants and analyzed …