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Ms211: Plans For Nazarbayev Visit To Houston And Tmc, Armin Weinberg

Works on Radiation Effects: 1990-2020

A list of things that Armin created in preparation for the visit by the President of Kazakhstan to Texas, Houston and the Medical Center. Very insightful with names and activities. See more at Armin Weinberg, PhD Papers and its finding aid.

Modulation Of The Rat Potassium Channel Kv1.5, Daniel Benjamin Saal

Yale Medicine Thesis Digital Library

1. Kv1.5 is a delayed rectifier-type potassium channel. We have examined the localization of the channel protein using a polyclonal antibody against Kv1.5. This channel is expressed in numerous regions of the brain, primarily in glial cells. Its expression is particularly intense in the endfoot processes which abut the microvasculature of the brain. It is also expressed in the cell bodies and cellular processes in the pituitary.2. Immunoprecipitation of the Kv1.5 protein, from HEK 293 cells which were transformed with the Kv1.5 gene, revealed that the channel is phosphorylated and that treatment of cells with dibutyryl cyclic AMP (dibcAMP) or …

Permeable, Non-Irritating Prodrugs Of Nonsteroidal And Steroidal Agents, Paul Ashton, Thomas J. Smith, Peter G. Glavinos, John D. Conklin, Peter A. Crooks, Robert M. Riggs, Tadeusz Cynkowski, Grazyna Cynkowska

Ophthalmology and Visual Science Faculty Patents

Prodrugs containing an active drug molecule linked to a polyethylene glycol group, and a method of use thereof are described. Exemplary soluble ester prodrugs contain naproxen, triamcinolone acetonide, gancyclovir, taxol, cyclosporin, dideoxyinosine, trihydroxy steroids, and flurbiprofen molecules linked to polyethylene glycol (PEG) groups. Pharmaceutical compositions containing these prodrugs, and a method of using these esters for treating disease states or symptoms are also described.

Nurses Alumni Association Bulletin, Fall 1997, Betty Piersol, Elizabeth K. Prisnock, Marian E. Smith, Margaret Summers, Sue Henrie-Strup, Maureen Mcvail

Nursing Alumni Bulletins

1997-1998 Meeting Dates Calendar

1998 Annual Luncheon-Meeting Notice

Officers and Committee Chairs

Bulletin Publication Committee

1997-1998 Meeting Dates Calendar

The President's Message

Treasurer's Report

Trivia and News About Our Graduates

Highlights of 1997

Keeping Kids Healthy After Hours

Scholarship Funds At Work

Tribute to Tanya

Medical Mission Outreach 1996

History Of The Jefferson Pin

Facts Not Fiction

Rib Ticklers

Mama Will Protect Me

Happy Birthday

Fiftieth Anniversary

Resume of Minutes of Alumni Association Meetings

Alumni Office News

Committee Reports

• Bulletin
• By-Laws
• Development
• Diploma School of Nursing Alumni Association-Mabel C. Prevost Scholarship Fund
• Nominating
• Relief Fund
• Satellite
• Social
• Scholarship

Luncheon Photos …

1997 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti

Health Care Marketing And The Internet, C. David Shepherd, Daniel Fell

Faculty Articles

This article presents research on the growing number of health care providers using the Internet as a health care marketing tool in the U.S. The author notes that the Internet is changing the way consumers seek healthcare related information as well as the way it can be provided to them. The results of the study suggest that consumers will increasingly rely on sources like the Internet for information, that health information will be a commodity on the Internet, that the Internet will help build relationships between providers and consumers and that marketers will be expected to develop and manage Internet-related …

Identification Of Mycobacterium Paratuberculosis Gene Expression Signals, John P. Bannantine, Raul G. Barletta, Charles O. Thoen, Robert E. Andrews Jr.

School of Veterinary and Biomedical Sciences: Faculty Publications

Mycobacterium paratuberculosis promoter-containing clones were isolated from a genomic DNA library constructed in the transcriptional-translational fusion vector pYUB76. The promoter-containing DNA fragments were identified in the surrogate host Mycobacterium smegmatis by expression of the promoterless lacZ reporter gene of pYUB76. The expression signals exhibited a wide range of strengths, as indicated by their corresponding β-galactosidase activities. Eight clones were sequenced and characterized further. Predicted open reading frames and codon usage were identified by computer analysis. Database searching for related sequences using the BLAST method revealed no homologies. Transcriptional activity was measured by slot-blot hybridization with steady-state RNA isolated from lacZ …

Anticoagulation And Elective Surgery., J. Spandorfer, G. Merli

Department of Medicine Faculty Papers

No abstract provided.

Nursing: A New Day, A New Way, Lin Zhan, Jane Cloutterback

New England Journal of Public Policy

The U.S. health care environment is changing rapidly. Its structure, financing, and delivery are being reconfigured toward an integrated system based on managed care. Increasingly, national interest in health promotion and disease prevention is moving care away from a disease-oriented, institutionally based model to a population-focused, wellness-oriented, and community-based system. Health care consumers are diversifying in age, ethnicity, and socioeconomic status. The approach emerging from these changes and others requires nursing to rethink, redesign, and retool its workforce to meet new challenges. This article analyzes nursing education, practice, and operations. The authors discuss the dilemmas and complexity of developing an …

Improving Workforce Conditions In Private Human Service Agencies: A Partnership Between A Union And Human Service Providers, James Green

New England Journal of Public Policy

In 1995 the Service Employees International Union Local 509 and four Massachusetts human service providers signed an unusual agreement to forge a partnership in which employers would remain neutral while the union approached its workers with an offer to advocate in the state legislature for greater funding for private human service employees and to promote cooperative relations with their employers. This study examines the context of the agreement and the pressures on public employee unions and small human service providers whose workforce copes with low wages, high turnover, meager benefits, and poor public image as well as the give-and-take between …

Job Mobility Of Entry-Level Workers: Black And Latina Women In Hospital Corridors, Maria Estella Carrión

New England Journal of Public Policy

Based on data from interviews with fifteen black and fifteen Latina women in entry-level jobs, this article discusses job access strategies, patterns of job mobility, and barriers to upward job mobility for low-income minority women in the hospital industry. Concentrated in the lowest wage levels and job tiers, they are quite diverse in subgroup composition, in age, and in training requirements. The research confirms that deficiencies in schooling and skills remain the major obstacles minority women confront when they apply for hospital jobs and restrict their opportunities once they are within the hospital labor market. Efforts to provide training and …

Myelin-Associated Glycoprotein Interacts With Neurons Via A Sialic Acid Binding Site At Arg118 And A Distinct Neurite Inhibition Site, Song Tang, Ying Jing Shen, Maria Elena Debellard, Gitali Mukhopadhyay, James L. Salzer, Paul R. Crocker, Marie T. Filbin

Publications and Research

Inhibitory components in myelin are largely responsible for the lack of regeneration in the mammalian CNS. Myelin-associated glycoprotein (MAG), a sialic acid binding protein and a component of myelin, is a potent inhibitor of neurite outgrowth from a variety of neurons both in vitro and in vivo. Here, we show that MAG’s sialic acid binding site is distinct from its neurite inhibitory activity. Alone, sialic acid–dependent binding of MAG to neurons is insufficient to effect inhibition of axonal growth. Thus, while soluble MAG-Fc (MAG extracellular domain fused to Fc), a truncated form of MAG-Fc missing Ig-domains 4 and 5, MAG(d1-3)-Fc, …

The Influence Of Case And Professional Variables On The Identification And Reporting Of Child Maltreatment: A Study Of Licensed Psychologists And Certified Masters Social Workers, David J. Hansen, Kurt M. Bumby, Lori M. Lundquist, Reginald M. Chandler, Peter T. Le, Kristine T. Futa

Department of Psychology: Faculty Publications

All 50 states have laws requiring mental health and other professionals to report suspected maltreatment. Unfortunately, many professionals who are mandated to report suspicions of child maltreatment often fail to recognize potential maltreatment or fail to report their suspicions. The present study examines several factors that may influence identification and reporting of child maltreatment. Subjects were licensed psychologists in the Midwest and certified Masters social workers in Nebraska. Child maltreatment included neglect, physical abuse, psychological maltreatment, and sexual abuse. Characteristics associated with the family or “case” (race, socioeconomic status of family, age of victim, type of maltreatment) were manipulated and …

Update - September 1997, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Cocaine Addiction: The Nemesis of Modern Culture

Analysis Of Bovine Herpesvirus 1 Transcripts During A Primary Infection Of Trigeminal Ganglia Of Cattle, Luis M. Schang, Clinton J. Jones

School of Veterinary and Biomedical Sciences: Faculty Publications

During an infection of nonneuronal cells, bovine herpesvirus 1 (BHV-1) gene expression proceeds in a well-defined cascade. Products of immediate-early (IE) genes are expressed first, and they activate expression of early (E) and late (L) genes. Although the same cascade is assumed to occur during an infection of neurons in trigeminal ganglia (TG) of cattle, no experimental data is available to support this hypothesis. Consequently, we analyzed BHV-1 gene expression in bovine TG at 1, 2, 4, 7, and 15 days postinfection (dpi). Infectious virus was detected in ocular swabs from 1 to 7 dpi but not 15 dpi. By …

Vol. 20 No. 3 (1997): Pacific Studies Front Matter, The Jonathan Nāpela Center For Hawaiian And Pacific Islands Studies

Pacific Studies

Pacific Studies is published two times a year by The Jonathan Nāpela Center for Hawaiian and Pacific Studies, Brigham Young University Hawai‘i #1979, 55–220 Kulanui Street, Lāʻie, Hawai‘i 96762, but responsibility for opinions expressed in the articles rests with the authors alone. Subscription rate is US$40.00 yearly, payable to The Jonathan Nāpela Center for Hawaiian and Pacific Studies. The Jonathan Nāpela Center for Hawaiian and Pacific Studies (formerly The Pacific Institute) is an organization funded by Brigham Young University Hawai‘i. The Center assists the University in meeting its cultural and educational goals by undertaking a program of teaching, research, and …

Vol. 20 No. 3 (1997): Pacific Studies Full Issue, The Jonathan Nāpela Center For Hawaiian And Pacific Islands Studies

Pacific Studies

Pacific Studies is published two times a year by The Jonathan Nāpela Center for Hawaiian and Pacific Studies, Brigham Young University Hawai‘i #1979, 55–220 Kulanui Street, Lāʻie, Hawai‘i 96762, but responsibility for opinions expressed in the articles rests with the authors alone. Subscription rate is US$40.00 yearly, payable to The Jonathan Nāpela Center for Hawaiian and Pacific Studies. The Jonathan Nāpela Center for Hawaiian and Pacific Studies (formerly The Pacific Institute) is an organization funded by Brigham Young University Hawai‘i. The Center assists the University in meeting its cultural and educational goals by undertaking a program of teaching, research, and …

Variation In Environmental Risk Perceptions And Information Sources Among Three Communities In El Paso, Theresa L. Byrd, James Vanderslice, Susan K. Peterson

RISK: Health, Safety & Environment (1990-2002)

The authors report the results of a pilot study of environmental risk and sources of environmental information in three socio-economically and culturally distinct communities in Texas.

Increased Focal Adhesion Kinase- And Urokinase-Type Plasminogen Activator Receptor-Associated Cell Signaling In Endothelial Cells Exposed To Asbestos, A Barchowsky, B M. Lannon, L C. Elmore, M D. Treadwell

Dartmouth Scholarship

Exposure of low-passage endothelial cells in culture to nonlethal amounts of asbestos, but not refractory ceramic fiber-1, increases cell motility and gene expression. These changes may be initiated by the fibers mimicking matrix proteins as ligands for receptors on the cell surface. In the present study, 1- to 3-hr exposures of endothelial cells to 5 mg/cm2 of chrysotile asbestos caused marked cell elongation and motility. However, little morphological change was seen when chrysotile was added to cells pretreated with either mannosamine to prevent assembly of glycophosphatidylinositol (GPI)-anchored receptors or with herbimycin A to inhibit tyrosine kinase activity. Affinity purification of …

Qsr1p, A 60s Ribosomal Subunit Protein, Is Required For Joining Of 40s And 60s Subunits., Dominic P. Eisinger, Frederick A. Dick, Bernard L. Trumpower

Dartmouth Scholarship

QSR1 is a recently discovered, essential Saccharomyces cerevisiae gene, which encodes a 60S ribosomal subunit protein. Thirty-one unique temperature-sensitive alleles of QSR1 were generated by regional codon randomization within a conserved 20-amino-acid sequence of the QSR1-encoded protein. The temperature-sensitive mutants arrest as viable, large, unbudded cells 24 to 48 h after a shift to 37 degrees C. Polysome and ribosomal subunit analysis by velocity gradient centrifugation of lysates from temperature-sensitive qsr1 mutants and from cells in which Qsr1p was depleted by down regulation of an inducible promoter revealed the presence of half-mer polysomes and a large pool of free 60S …

Jefferson Alumni Bulletin – Volume Xlvi, Number 4, September 1997

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLVI, Number 4, September 1997

University Awards Honorary Degree to Dr. Davis, Page 5

Luscombe, miller, and Staas Receive the Alumni Achievement Awards, Page 6

Clinic Presentations Address a Range of Fields, Page 8

Receptions Across Country Welcome College Leaders, Page 12

Landmark Diabetes Prevention Program, Page 21

Cardiology and Cardiothoracic Surgery Reception, Page 25

Annual Giving Tops $1.7 Million, Page 30

Sqt1, Which Encodes An Essential Wd Domain Protein Of Saccharomyces Cerevisiae, Suppresses Dominant-Negative Mutations Of The Ribosomal Protein Gene Qsr1., Dominic P. Eisinger, Frederick A. Dick, Elke Denke, Bernard L. Trumpower

Dartmouth Scholarship

QSR1 is an essential Saccharomyces cerevisiae gene, which encodes a 60S ribosomal subunit protein required for joining of 40S and 60S subunits. Truncations of QSR1 predicted to encode C-terminally truncated forms of Qsr1p do not substitute for QSR1 but do act as dominant negative mutations, inhibiting the growth of yeast when expressed from an inducible promoter. The dominant negative mutants exhibit a polysome profile characterized by 'half-mer' polysomes, indicative of a subunit joining defect like that seen in other qsr1 mutants (D. P. Eisinger, F. A. Dick, and B. L. Trumpower, Mol. Cell. Biol. 17:5136-5145, 1997.) By screening a high-copy …

Identification Of A Gal/Galnac Lectin In The Protozoan Hartmannella Vermiformis As A Potential Receptor For Attachment And Invasion By The Legionnaires' Disease Bacterium, Chandrasekar Venkataraman, Bradley J. Haack, Subbarao Bondada, Yousef Abu Kwaik

Microbiology, Immunology, and Molecular Genetics Faculty Publications

The Legionnaire's disease bacterium, Legionella pneumophila, is a facultative intracellular pathogen which invades and replicates within two evolutionarily distant hosts, free-living protozoa and mammalian cells. Invasion and intracellular replication within protozoa are thought to be major factors in the transmission of Legionnaire's disease. Although attachment and invasion of human macrophages by L. pneumophila is mediated in part by the complement receptors CR1 and CR3, the protozoan receptor involved in bacterial attachment and invasion has not been identified. To define the molecular events involved in invasion of protozoa by L. pneumophila, we examined the role of protein tyrosine phosphorylation …

The Relationship Of Health-Promoting Behaviors To Hospital Admissions In Adults With Congestive Heart Failure, Debbie Mcfalls

MSN Research Projects

Successful medical treatment for acute health conditions has precipitated an increase in the number of chronic health problems. One such chronic condition is congestive heart failure. Heart failure is the number one discharge diagnosis among Medicare recipients. The financial burden for the management of this chronic condition is astronomical. Health care providers are commissioned to manage this chronic illness prudently. The purpose of this correlational descriptive study was to determine if there was any relationship between health-promoting behaviors and readmission rates of adults with congestive heart failure. A convenience sample of participants was obtained from a hospital facility. Subjects were …

A Preliminary Analysis Of Health Lifestyles Between International Students And American Students At Western Kentucky University, Mei Zhu

Masters Theses & Specialist Projects

The purpose of this research was to assess the lifestyle of international students at Western Kentucky University (WKU) and to compare the lifestyles of international and American students and subgroups of international students. The Lifestyle Questionnaire (LSQ), was a 26-item personal health lifestyle test, which had six sections (nutrition, exercise, smoking, alcohol and drugs, safety, and stress). The test-retest reliability of LSQ was evaluated by Pearson Correlation Coefficient (r) and was .89. During October and November 1997, 55 international students and 64 American students at WKU finished the LSQ. Significant differences were found between the American student group and the …

Comparisons Of Outcomes In A Pediatric Primary Care Clinic In Patients Treated By A Physician Or A Nurse Practitioner, Ken Burnette

MSN Research Projects

Physician availability during the 2 0th century has waxed and waned. During periods of physician shortage and surplus, there have always been underserved segments of our society. Nurse practitioners (NPs) have provided care for these underserved populations. Unfortunately, 30 years after the first NPs began to practice there remain underserved populations and underutilized practitioners. The purpose of this study was to compare outcomes between physicians and practitioners. The research questions are the following: Is there a difference in patient's satisfaction between care provided by a physician and a nurse practitioner? Does care differ when initiated by a physician or a …

The Relationship Between Meaning In Life And The Occurrence Of Drug Abuse: An Epidemiological Retrospective Study, Ben Howard

Masters Theses & Specialist Projects

Humans have been using plant-derived drugs for as long as we have recorded history. Significant negative consequences related to drug abuse have occurred in the areas of health, social issues, family relations, legal systems, and economic productivity. The purpose of this study was to explore the relationship between meaning in life and drug abuse. An epidemiological, retrospective study was performed to compare personal meaning in life between individuals receiving inpatient treatment for drug abuse and a group of non-drug abusing controls. Study participants completed the Purpose-In-Life Test and Life Attitude Profile-Revised. On both instruments, the inpatient drug abusing subjects were …

The Beneficial Effect Of Vitamin E And Selenium During Experimental Chagas' Disease, Yue Hou

Masters Theses & Specialist Projects

The present study was conducted to determine if vitamin E and selenium could have a positive synergistic effect during experimental Chagas' disease. In the first phase of the study, 25 female C3HeB/FeJ mice were infected with a Brazil strain of Trypanosoma cruzi while receiving vitamin E supplementation of 0 IU/kg, 200 IU/kg, 400 IU/kg, 600 IU/kg, 800 IU/kg in their diets. In the second phase, 20 female C3HeB/FeJ mice were infected while receiving 400 IU/kg vitamin E plus selenium supplementation of 2 ppm, 4 ppm, 8 ppm, 16 ppm in their drinking water. The results demonstrate that vitamin E does …

Health Beliefs And Practices Among African American Men Concernign Prostate Cancer Screening, Beverly A. Howard

MSN Research Projects

African American men have the highest incidence of prostate cancer in the United States and the world (American Cancer Society [ACS], 1996). Nevertheless, studies have indicated that African American men are the least likely to participate in prostate cancer screening programs (Myers, Wolfe, Balshem, Ross, & Chodak 1994; Underwood, 1991). Many researchers have hypothesized that health beliefs influence health practices. Therefore, this study examines the health beliefs and practices among African American men concerning prostate cancer screening. Becker's Health Belief Model was used as the conceptual framework for this study. The research questions examined the health beliefs and practices among …

Effects Of An Otitis Media Prevention Program On Healthy Infants, Rena D. Matthews

MSN Research Projects

Otitis media (OM) is the leading illness among infants and children. Risk factors have been identified which increase occurrence of OM in infants. The purpose of the quasi- experimental study was to determine if teaching OM prevention to parents of healthy infants would reduce the occurrence rate of OM. The theoretical framework for the research was based on the Health Promotion Model (Pender, 1996) which focuses on the integration of health-promoting behavior into lifestyles. The research hypothesis was that there would be no statistically significant difference in the effects of an OM prevention program on healthy infants and a control …