Digital Commons Network^™

Reference Proteins To Improve Core 1 And Core 2 Alzheimer's Disease Csf And Plasma Biomarkers, Linda Karlsson, Nicolas R Barthélemy, Kanta Horie, Suzanne E Schindler, Brian A Gordon, Cyrus A Raji, Tammie L S Benzinger, John C Morris, Randall J Bateman, Et Al.

2020-Current year OA Pubs

Concentration-based fluid biomarkers represent an informative and cost-effective way to detect and monitor Alzheimer's disease (AD) pathology. However, non-AD-related interindividual variation in biofluids can also affect biomarker concentrations. Here, we investigated whether normalization of CSF and plasma biomarkers to reference proteins, such as amyloid-β40 (Aβ40) and non-phosphorylated mid-region tau (np-tau), improves their robustness and reliability of representing AD pathology load. Using the Swedish BioFINDER-2 cohort [n = 1702, 50.7% male, mean (standard deviation) age 68.4 (12.2) years], we compared the associations between tau/Aβ-PET load and fluid biomarkers alone versus biomarkers in a ratio with a reference protein (Aβ40 or np-tau) …

Polymorphism Of The Mx Gene In Riau Kampung Chickens, Elfawati Elfawati, Restu Misrianti, Sadarman Sadarman

Jurnal Ilmu Ternak Universitas Padjadjaran

One of the genetic markers for avian influenza is the Mx gene. The purposed of this study was to determine the polymorphism of the Mx gene of kampung chicken in Riau Province. A total of 61 samples from three subpopulations have been genotyped using PCR-RFLP. Allele and genotype frequencies have been calculated using PopGene. The Mx gene was amplified, producing a DNA fragment measuring 299 base pairs. This fragment was digested with the Hpy81 enzyme, which yielded three genotypes: the AA genotype showed by a single 299 bp band; AG showed by 299, 200, and 99 bp bands; and GG …

Redesigning A Fitness App Interface For Physiological Constrained Users*, Joseph E. Manzanillo

Campus Research Month

As fitness tracking converges with medical monitoring, inclusive design becomes a matter of health equity. This research utilizes a Polar Beat redesign to address exclusionary "sporty" aesthetics that can exclude 300 million colorblind users. Based in Human-Computer Interaction (HCI), the study implements WCAG AA standards and color-blind-verified filters to mitigate data loss during Situational Induced Impairment (SIID), when high-intensity exercise compromises cognitive and visual processing. By optimizing user journeys for Paralympic and geriatric archetypes, this work demonstrates that accessibility is the essential bridge transitioning mobile fitness apps into viable, inclusive instruments for clinical medical use.

Psychosocial Mediators Of A Physical Activity And Dietary Intervention In Pregnant Women With Overweight Or Obesity, Meghan Baruth, Sarah Wilcox, Jihong Liu, Rebecca Schlaff

Faculty Publications

Background

Mediation analyses provide insight into both ‘pieces’ of the mediation chain; they allow us to look into the ‘black box’ that is behavior change. They allow researchers to better understand the ‘how’ of an intervention’s effects and/or the ‘why’ behind why an intervention worked or did not work. The lack of publications in pregnant populations highlights the need for additional studies to be conducted and published. The purpose of this study is to examine the psychosocial mediators of physical activity and dietary outcomes in a sample of pregnant women with overweight or obesity participating in the Health in Pregnancy …

Quality Improvement Project: Educating Nursing Faculty On Animal-Assisted Therapy: Enhancing Knowledge And Confidence To Improve Program Outcomes, Sarah J. Whitwell

Doctor of Nursing Practice Projects

The purpose of this quality improvement project was to evaluate whether an educational intervention on animal-assisted therapy (AAT) improved nursing faculty perceived knowledge and confidence in using AAT to improve program outcomes. The problem addressed was the limited knowledge and confidence among nursing faculty regarding the use of non-traditional, evidence-based strategies to support student mental health. This project was guided by the Stetler Model of Evidence-Based Practice and Lewin’s Change Theory and used a quasi-experimental, one-group pre–post design. The project was conducted with nursing faculty teaching in a baccalaureate program at a four-year public university in Oklahoma. A 10-item Likert-scale …

The Influence Of Lower-Body Explosive Power, Speed, And Eye-Foot Coordination On Long Jump Performance: A Path Analysis Study, Alwi Fahruzy Nasution, Imanuddin Siregar

Indonesian Journal of Research in Physical Education, Sport, and Health

Background: Long jump performance is influenced by various physical and coordinative components, particularly lower-body explosive power, running speed, and eye-foot coordination. However, limited studies have simultaneously examined the predictive relationships among these variables using a path analysis model among university students in physical education programs. Objective: This study aimed to analyze the direct and indirect predictive relationships among lower-body explosive power, speed, eye-foot coordination, and long jump performance. Methods: This study employed a quantitative, cross-sectional, correlational design with path analysis. The sample consisted of 30 students selected using a total sampling technique. Data were collected using standardized physical performance tests, …

Improving Academic Learning Time Effectiveness Through Lesson Study In Elementary Physical Education, Nora Antika, Meirizal Usra, Wahyu Indra Bayu, Iyakrus Iyakrus, Herri Yusfi, Arizky Ramadhan, Asha Hasnimy Mohd Hashim, Japhet Ndayisenga, José Vicente García-Jiménez

Indonesian Journal of Research in Physical Education, Sport, and Health

Background: Academic Learning Time in Physical Education (ALT-PE) is a key indicator of instructional effectiveness, reflecting the time students spend actively engaged in meaningful learning activities. However, PE lessons often involve excessive Management and waiting time, reducing opportunities for active participation. Although Lesson Study (LS) is recognized as a collaborative professional development approach that can improve instructional quality, its impact on ALT-PE remains underexplored. Objective: This study examined the effectiveness of Lesson Study (LS) in improving instructional effectiveness and optimizing ALT-PE among elementary school PE teachers. Methods: A qualitative-dominant mixed-methods action research design was employed involving 10 PE teachers from …

The Role Of Ai Chatbots In Dentistry: A Systematic Review Of Applications, Benefits, Challenges, And Future Directions, Arushi Kumari, Upasana Reddy, Mamatha Shekar Shetty

International Arab Journal of Dentistry

Introduction: Artificial intelligence (AI) aims to develop systems capable of performing tasks that require human intelligence, including learning, reasoning, and decision-making. In dentistry, AI is increasingly applied across multiple specialties, such as operative dentistry, periodontics, orthodontics, oral and maxillofacial surgery, and prosthodontics, particularly in diagnosis, treatment planning, and prognosis.

Objectives: This review focuses on the application of AI chatbots in dentistry, exploring their potential benefits and limitations. The objective of this review is to addresses the questions: 1. Which dental domains employ AI chatbots? 2. What evidence exists for their performance in diagnostics, patient engagement, and education? 3. What ethical, …

Six-Week Time-Restricted Eating Lowers Premature Mortality Risk In Overweight Early Elderly Adults: Evidence From A Body Shape Index, Przemysław Domaszewski, Mariusz Konieczny

Baltic Journal of Health and Physical Activity

Background: A Body Shape Index (ABSI) is an anthropometric indicator combining waist circumference, weight, and height, providing a BMI-independent measure of central obesity and a recognized predictor of mortality. Despite its relevance, research on ABSI in early elderly populations remains limited. This study assessed the impact of a six-week time-restricted eating (TRE) intervention on ABSI z-scores in overweight adults aged 65–74, with attention to gender differences. Materials and Methods: A total of 116 participants were randomized into a TRE group (16:8 fasting window from 8:00 PM to 12:00 PM) or a control group maintaining habitual eating. ABSI z-scores were evaluated …

Supporting School Readiness: A Visual-Motor Integration Program For Children Ages 2.5-10, Bailey Williams, Wendy Tremaine, Carla Hamilton

Spring 2026 OTD Capstone Symposium

This capstone project focused on supporting school readiness through the development and implementation of a visual-motor integration (VMI) program for children ages 2.5–10 with developmental delays. A needs assessment was conducted to identify gaps in caregiver knowledge and resources related to VMI development. In response, a 6-week educational program was created, incorporating targeted activities and caregiver education to promote VMI skill development. Findings indicated improved caregiver understanding of VMI concepts and increased confidence in implementing strategies at home. These results highlight the importance of early intervention and caregiver involvement in supporting children’s academic readiness and overall developmental outcomes.

Burnout Sentinel: An Early Warning System For Student Burnout Using Workload And Recovery Indicators, Minh Duy Do

Expo Student Presentations

2026 Spring Expo Video Essay Presentation

• Biological & Life Sciences
• Health Sciences & Health Professions
• Physical & Applied Sciences
• Service-Learning
• Social & Behavioral Sciences

An Evidence-Based Educational Intervention To Enhance Nurses' Knowledge Of Metabolic Syndrome In Residential Care Facilities, Marie Tanyi

Doctor of Nursing Practice Scholarly Projects

The project addresses a critical gap in nursing education by implementing a structured, evidencebased educational intervention led by an Advanced Practice Registered Nurse (APRN) to improve nurses’ knowledge of metabolic syndrome in residential care facilities. The purpose was to determine whether this intervention could significantly enhance nurses’ understanding and management of metabolic syndrome, a complex cluster of disorders present in adult populations. Nine nurses participated in targeted educational sessions focusing on definition, diagnosis, complications, and evidence-based prevention and management strategies. Each participant completed the Metabolic Syndrome Knowledge Scale (MSKS) questionnaire before and after the intervention to assess changes in knowledge. …

Evaluation Of Seal!Nd: School Year 2024-2025, Shawnda Schroeder, Rashid Ahmad

Indigenous Health Faculty Publications

Dr. Schroeder and Rashid worked with the team at the Oral Health Program to collect data on the clinical reach of the School-based Sealant program (SEAL!ND), the referral practices, dental sealant cost savings, and perceptions of school personnel regarding their experiences with the program. SEAL!ND continues to make a measurable difference in improving children’s oral health by increasing access to preventive care, reducing barriers for families, and supporting schools in meeting the needs of their students. The program’s impact is reflected not only in the thousands of services provided each year, but also in the strong satisfaction and gratitude expressed …

Une Com Spring Research Bulletin May 2026, Une Com Research & Scholarship

Osteopathic Student Research Symposia

Bulletin including abstracts from the University of New England College of Osteopathic Medicine’s 2026 inaugural Spring Research Update and Lightning Talk event.

Music Listening While Studying And Academic Performance Among College Students With Attention Deficit And Hyperactivity Disorder, Raihan K. Khan, Md Towfiqul Alam, Madalynn Nofplot, Sojib Bin Zaman, Catherine L. Zaman

Faculty Scholarship

Evidence on whether music listening supports academic performance, particularly among students with attention deficit and hyperactivity disorder (ADHD), remains mixed. We explored associations between music listening while studying and academic performance (GPA: grade point average) among college students, and to evaluate whether the associations differed by ADHD status. We analyzed cross-sectional survey data from college students and conducted linear regression models with self-reported GPA as the dependent variable. Models were adjusted for sex, academic level, college affiliation, primary study location, weekly study hours, and preferred genre of music. A total of 541 students participated. Most of the students were at …

Wright State University's Celebration Of Student Research, Scholarship & Creative Activities From Wednesday, April 1, 2026, Wright State University

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's Celebration of Student Research, Scholarship & Creative Activities on April 1, 2026.

Deep Learning-Based Automated Pneumonia Detection From Chest X-Rays: A Comparative Study Of Custom Cnn And Transfer Learning Architectures, Ahmed Sajim

Honors Theses

Pneumonia is a leading global cause of mortality, claiming approximately 2.5 million lives an-nually and placing exceptional diagnostic pressure on radiologists in resource-limited settings. Manual interpretation of chest X-ray (CXR) images is time-consuming, subject to inter-observer variability, and limited by radiologist availability. This thesis presents a systematic investiga-tion into deep learning-based automated pneumonia detection comparing five convolutional neural network (CNN) architectures: a custom-designed 2D CNN and four pretrained transfer learning models—ResNet, DenseNet, MobileNet, and VGG19.

A targeted data augmentation pipeline addresses the severe class imbalance in the Kag-gle Chest X-Ray Pneumonia dataset, expanding the Normal class from 1,583 to 9,495 …

Folic Acid–Carbon Dot–Gemcitabine Nanoparticles For Targeted Cancer Drug Delivery, Irfan Huda, Hua Mei

SPARK Symposium Presentations

This project aims to develop a folic acid-attached carbon dot nanoparticle system (FA-CDs-GEM) for the targeted delivery of gemcitabine to cancer cells. While gemcitabine is widely used, its effectiveness is limited because a short in vivo half life and lack of selectivity, which lead to severe side effects. Carbon dots offer a simple and modifiable platform as the drug delivery and bioimaging agent. Conjugation of folic acid to the carbon dots enables selective targeting of cancer cells that overexpress folate receptors. In this study, we synthesized and characterized FA-CD-GEM nanoparticles and developed an HPLC calibration curve of GEM to accurately …

Increased Backbone Rigidity Of Artificial Transcription Factors, Jasmine Glover, Emma Otey, Joanna K. Kwao, Nicholas Truex

Senior Theses

Programming DNA-binding proteins is an effective strategy for developing therapeutics that regulate gene expression. These proteins can directly bind to DNA to activate or repress transcription of specific genes. Zinc finger proteins are a class of DNA-binding proteins commonly found in eukaryotic organisms. Their DNA-binding function is derived from unique amino acid sequences within each domain that recognizes specific nucleotides, allowing each finger to selectively recognize three DNA base pairs. Adjoining of multiple domains in tandem allows recognition of a specific DNA sequence. Artificial transcription factors can be made of multiple zinc finger domains arranged in tandem and engineered to …

2026 Research Day Program, Lincoln Memorial University

Research Day

This program contains abstracts and presentation summaries from LMU's 2026 Annual Research Day conference.

Pelvic Inflammatory Disease: A Narrative Review Of Disparities Between Black And White Women In The United States And Strategies For Improvement, Lynne Li, Jessica Schlewitt

Journal of Patient-Centered Research and Reviews

Pelvic Inflammatory Disease (PID) is an inflammatory syndrome of the upper female reproductive organs caused by infection, most commonly via Neisseria gonorrhoeae or Chlamydia trachomatis, spreading to one or more reproductive organs. With PID responsible for many of the major morbidities of sexually transmitted infections (STIs), such as ectopic pregnancy and chronic pelvic pain, the urgency is high to mitigate the impacts of untreated PID, especially in higher-risk populations. This paper discusses the current disparities in PID diagnosis, treatment, and management between Black and white women and proposes interventions to reduce health inequalities involving PID. To conduct this narrative review, …

Deep Learning Based Approaches For Low Cost Defense Detection, Adele J. Noel-Rickert

All NMU Master's Theses

Pulmonary fibrosis is a progressive interstitial lung disease characterized by the accumulation of fibrotic tissue within the lungs, leading to impaired respiratory function and reduced quality of life. Early detection is important for disease management; however, accurate diagnosis often relies on high-resolution computed tomography (CT), which may not be accessible in all clinical settings. Chest radiography provides a lower-cost and widely available imaging modality, but interpretation of chest X-rays for fibrotic disease can be challenging due to subtle radiographic patterns and overlapping anatomical structures. This thesis investigates the use of multimodal deep learning techniques to assist in pul- monary fibrosis …

Factors Associated With Lapses In Care Among People Living With Hiv In South Carolina, Xueying Yang Ph.D., Fanghui Shi, Shujie Chen, Gavi Samuel, Bankole Olatosi Ph.D., Sharon Weissman, Xiaoming Li Ph.D., Jiajia Zhang Ph.D.

Faculty Publications

Utilizing statewide electronic health records (EHR) data, this study aims to assess the factors determining the occurrence of lapses in HIV care among people with HIV (PWH) in South Carolina (SC). All adult (≥ 18 years old) PWH who were diagnosed with HIV between 2006 and 2018 with at least two HIV care encounters and at least 1-year follow-up record were included in the analysis. The outcome, a lapse in care, was defined as a repeated measure of HIV care encounter that occurs over a year following the previous visit. Generalized Estimation Equation models were employed. The study cohort had …

Implementation And Costs Of A Food Insecurity Resource Navigation Program For Primary Care Patients With Diabetes And Hypertension In South Carolina, Deeksha Gupta, Darin Thomas, Stella Coker Watson Self Ph.D., Ms, Edward A. Frongillo Jr. Ph.D., Alain H. Litwin, Joseph A. Ewing, Lynnette Ramos-Gonzalez, Lynnette Ramos-Gonzalez

Faculty Publications

Objective

To examine food insecurity resource navigation program costs and how navigation intensity relates to clinical outcomes, healthcare costs, and quality of life (QOL) for diabetes and/or hypertension patients.

Methods

This retrospective study included patients receiving resource navigation (July 12, 2021-December 31, 2022 with twelve-month follow-up) across three primary care practices in South Carolina's largest health system. Participants were 18+ years old (from electronic medical records/Epic), had food insecurity (from Hunger Vital Sign™), and diabetes and/or hypertension (from Epic registries). Matched controls came from food insecurity screening-only practices. Patients in each group (n= 219) had diabetes (9.13%), hypertension …

Comparative Analysis Of Mlp And Cnn Models For Cardiac Arrhythmia Classification, Veltman Okey-Ejowhor, Vahid Emamian

Posters - 2026

Electrocardiogram (ECG) is a record of the electric activity of the heart over time. ECG analysis plays a pivotal role in diagnosing critical heart conditions. Significant developments have been made in the realm of deep learning and applied artificial intelligence. These deep learning models have been utilized heavily because of their ability to analyze deep morphological features of each signal. The model architecture used in this study is a convolutional neural network (CNN) combined with a multi-layered perceptron (MLP). The MLP acts as an input filter that classifies normal heartbeat signals from abnormal. The CNN is the second filter in …

Using Ai-Based Predictive Scheduling To Improve Patient Flow And Reduce Wait Times In Healthcare Clinics, Oscar Martinez

Posters - 2026

• Healthcare systems face increasing challenges in patient access and wait times
• Average wait times for specialist care continue to rise, creating:
  • Delays in treatment
  • Reduced patient satisfaction
  • Increased system inefficiencies (Sanford, 2025)
• A major contributor is operational bottlenecks, defined as:
  • Points of congestion that slow or disrupt service flow
• Hospitals typically operate under process layouts, which:
  • Handle diverse patient needs
  • Reduce specialization efficiency
• Contributing factors to bottlenecks:
  • Physician shortages and burnout
  • Administrative burden
  • Inefficient scheduling systems (Moura & Pinho, 2025)
• AI offers potential solutions through:
  • Predictive scheduling
  • Automation of administrative processes
  • Data-driven optimization of patient flow

Gompertz Growth With A Shared Carrying Capacity Optimally Simulates Primary And Metastatic Tumor Growth Dynamics, Pirmin Schlicke, Preethi Korangath, Xiaoxi Pan, Caner Ercan, Kathleen Gabrielson, Lyndsey Werhane, Yinyin Yuan, Sébastien Benzekry, Robert Ivkov, Heiko Enderling

Faculty, Staff and Student Publications

Background: Cancer is a systemic disease with most deaths attributed to metastatic burden. Primary and metastatic tumors, albeit at different anatomic locations, are interconnected through multiple biological processes. Pre-clinical and clinical observations of growth acceleration of metastases after surgery, or abscopal effects outside the radiation field are widely reported, yet reliably triggering favorable and avoiding unfavorable systemic responses remains an unmet clinical need. Understanding local and systemic tumor interaction dynamics will help guide future treatments.

Methods: We analyze the data of multiple in vivo tumor models. We formalize the systemic interplay of tumors as mathematical differential equation and calibrate parameters …

Impact Of Cannabis And Cannabis Legalization On Us Atrial Septal Defect Rates, Albert Stuart Reece, Hulse

Research outputs 2022 to 2026

Atrial septal defect (ASD) affects 1:11.3 children in some US states; however, the antecedents of these trends are yet to be identified. A total of 1882 ASD rates (ASDRs) for 2003–2020 were sourced from the National Birth Defects Prevention Network reports. A total of 406,893 ASDs are reported. Substance (cigarettes, binge alcohol, cannabis, cannabinoids, analgesics, cocaine) exposure data were taken from the National Survey of Drug Use and Health. Income and ethnicity data were derived from the US Census. Adjustment was performed by mixed effects, survey and generalized additive regression. Causal analysis was by inverse probability weighting and E-values. Data …

Longitudinal Assessment Of Health-Related Quality Of Life In Adults With Ckd, Owen Ng, Teixeira-Pinto, Anh Kieu, Anita Van Zwieten, Anoushka Krishnan, Kirsten Howard, Wai H. Lim, Jeremy R. Chapman, Simon D. Roger, Michael J. Bourke, Shaundeep Sen, Steven J. Chadban, Carol A. Pollock, Allison Jaure, Jonathan C. Craig, Jean Yang, Germaine Wong

Research outputs 2022 to 2026

Key Points: Dialysis linked with poorer quality of life compared with transplant patients and patients with CKD. Quality of life trends were similar in both domain-specific and overall quality-of-life measures. Background: There are sparse data about the change in health-related quality of life (HRQoL) with the temporal progression of CKD. In this study, we assessed the association between change in CKD stages, overall and domain-specific quality of life and determined the factors that were associated with this change. Methods: Data were sourced from a multicenter study that included 1290 adult patients aged 18 years and older across six centers in …

Learning In Motion: How Small Groups Can Promote Self-Regulated Learning In Physical Therapy Students, Sara Mclaren

STEMPS Theses & Dissertations

Self-regulated learning (SRL) is a critical skill for success in rigorous graduate health professions programs, where students must independently manage complex academic demands. Despite its importance, limited research has examined SRL processes among Doctor of Physical Therapy (DPT) students in the didactic phase of training. Guided by Zimmerman’s cyclical model of self-regulated learning, this study examined SRL behaviors among second-year DPT students and explored how small group learning contexts may influence engagement in SRL processes and academic performance.

This mixed-methods study included 39 DPT students enrolled in a physical therapy program at a public university in the southeastern United States. …