Digital Commons Network^™

Delineating Differences In Firing Rate Estimates Of Healthy And Parkinsonian Single-Unit Basal Ganglia Recordings, Richard R. Foster, Cheng Ly

Biology and Medicine Through Mathematics Conference

No abstract provided.

A Size-Structured Approach For Modeling Coral-Algal Dynamics, Anayse Miller, Julie C. Blackwood, Lauren M. Childs

Biology and Medicine Through Mathematics Conference

No abstract provided.

Computation Models Of The Primary Auditory Cortex, Jonathan Gonzalez Martinez, Quynh-Anh Nguyen

Biology and Medicine Through Mathematics Conference

No abstract provided.

Geometry-Driven Changes In Pressure And Flow Dynamics In Control And Coarcted Aortic Hemodynamics, Md Arifuzzaman, Mette Olufsen, Mansoor Haider

Biology and Medicine Through Mathematics Conference

No abstract provided.

Computational Fluid Dynamics Model For Assessing Surgical Strategies For Liver Shunt Closure In Dogs, Schuyler Brennan, Nathan Nelson, Mette Olufsen

Biology and Medicine Through Mathematics Conference

No abstract provided.

Modeling The Effects Of Chronic Stress On Type 2 Diabetes, Kris Mae Pasia

Biology and Medicine Through Mathematics Conference

No abstract provided.

A Mechanistic Model Of Adhesion, Inflammation, Sleep, And Pain In Sickle Cell Patients, Milan Marsh, Rebecca Segal

Biology and Medicine Through Mathematics Conference

No abstract provided.

Positive Affect And Sleep Quality As Predictors Of Pain Onset In Pediatric Sickle Cell Patients, Eunice Clark, Reginald Mcgee, Cecelia Valrie, Rebecca Segal, Angela Reynolds

Biology and Medicine Through Mathematics Conference

No abstract provided.

A Logic-Based Differential Equation Model Of Endothelial Cell Function, Ella Froedge, Scarlett Hamilton, Mitchel Colebank

Biology and Medicine Through Mathematics Conference

No abstract provided.

A Multiscale Computational Framework Coupling Pulmonary Arterial Blood Flow And Lung Tissue Perfusion, Nigar Sultana, Hangjie Ji, Mette Sofie Olufsen

Biology and Medicine Through Mathematics Conference

No abstract provided.

Understanding Dengue Spread In Córdoba, Argentina Through Spatial Epidemiological Modeling, Mohammad Mihrab Uddin Chowdhury

Biology and Medicine Through Mathematics Conference

No abstract provided.

Modeling Serotonin Metabolism Towards A Diagnostic Skin Test For Depression, Joel Greenfield

Biology and Medicine Through Mathematics Conference

No abstract provided.

Comparing Mathematical Models Of Systemic Infection Responses, Laura M. Witzel

Biology and Medicine Through Mathematics Conference

No abstract provided.

A Phylogeny Informed Mathematical Model Of Hpai H5n1 Transmission And Control In Multi Host Systems, Oluwatosin Babasola

Biology and Medicine Through Mathematics Conference

No abstract provided.

Mathematical Modeling Of A Coral-Symbiont System To Assess Heat-Induced Bleaching, Anna Zittle, Angela Reynolds, Rebecca Segal, Liza Roger, Nastassja Lewinski

Biology and Medicine Through Mathematics Conference

No abstract provided.

Mathematical Modeling Of The Combined Effects Of Thermal Burn And Local Irradiation, Quintessa Hay, Rachel Jennings, Amy Creel, Kyle Gaffney, Christina Wagner, Kidist Maxwell, Ginu Unnikrishnan, Tyler Dant

Biology and Medicine Through Mathematics Conference

No abstract provided.

Parameter Sensitivity, Identifiability, And Estimation For A Data-Driven Model Of Malaria, Katharine Gurski, Kathleen Hofman

Biology and Medicine Through Mathematics Conference

No abstract provided.

Data-Driven Modeling Approaches For Epidemiological Applications Using County-Level Data, Mansoor A. Haider

Biology and Medicine Through Mathematics Conference

No abstract provided.

Mechanistic Basis Of Post-Treatment Control Of Shiv After Huad5sivgag/Tat, And1 Pgt121 Therapy2, Sirawit A. Srakaew

Biology and Medicine Through Mathematics Conference

No abstract provided.

Modeling The Dynamics Of Infectious Disease Transmission Through Wastewater Surveillance: Applications To Covid-19 Epidemiology, Ephraim Agyingi, Michael Kostrna

Biology and Medicine Through Mathematics Conference

No abstract provided.

Impact Of The Dose And The Number Of Transmitted/Founder Viruses On Siv Dynamics, Sunil Maity, Vitaly V. Ganusov

Biology and Medicine Through Mathematics Conference

No abstract provided.

Agentic Scientific Machine Learning For Autonomous Model Discovery In Systems Pharmacology, Nazanin Ahmadi, George Karniadakis

Biology and Medicine Through Mathematics Conference

No abstract provided.

Altsim: A Simulation Of Asian Longhorned Tick (Haemaphysalis Longicornis) Population Dynamics And Transmission Of Theileria Orientalis, Shania Sanderson, Holly Gaff

Biology and Medicine Through Mathematics Conference

No abstract provided.

Assessing Lagged Temperature Effects On Mosquito Life-History Traits, Nusrat Tabassum Dr.

Biology and Medicine Through Mathematics Conference

No abstract provided.

Attractor Reconstruction And Their Topological Data Analysis For Seizure Onset Detection, Kevin Slote, Igor Belykh, Mukesh Dhamala, Marrium Shamshad, Kelley Smith

Biology and Medicine Through Mathematics Conference

No abstract provided.

Mitigating Parameter Identifiability Issues Through Model Calibration On The Data-Informed Active Subspace: An Example In Tumor Growth, Allison L. Lewis, Rebecca A. Everett

Biology and Medicine Through Mathematics Conference

No abstract provided.

Accesstem: How Small Colleges Can Open Stem Pathways For Local High School Students, Dina D. Isakov

Program in Community Action (PICA)

This paper reflects my experience developing ACCESStem as part of the Program in Community Action (PICA) center at Connecticut College. ACCESStem is a community-engaged research project designed to create hands-on, lab-based STEM workshops for local high school students in New London. ACCESStem was built on the premise that even small liberal arts colleges can hold a meaningful impact on helping diversify the science workforce. Over the course of three years, this project took shape through my relationships with STEM faculty on campus and relationships with staff at the Holleran Center for Community Action. This paper works to begin contextualizing the …

Is2c2: A Cointelligent Platform For Mechanistic Discovery Of Disease Cellular Crosstalk, Jianting Sheng, Ju Young Ahn, Li Yang, Zhihao Wan, Shaohua Qi, Xiaohui Yu, Zhan Xu, Yuliang Cao, Matthew Vasquez, Amna Irfan, Yuanyuan Zhu, Hong Zhao, Zheng Yin, Ying Zhu, Yunfeng Ding, Alireza Faridar, Lin Wang, Fengshuo Liu, Hongxia Wang, Zhigang Ji, Dongxue Mao, Michael Chan, Daniel Kermany, Wenjuan Dong, Doo Yeon Kim, Xiang H-F Zhang, Stephen T C Wong

Faculty, Staff and Students Publications

Large language models (LLMs) have demonstrated impressive capabilities in summarization, reasoning, and content generation, yet their inability to directly interpret large-scale omics data has limited their utility in data-driven hypothesis generation-particularly in mechanism discovery that demands the integration and interpretation of multimodal datasets, heterogeneous models, and deep domain expertise. Conversely, traditional computational algorithms excel at quantitative analysis of omics data but often rely heavily on labor-intensive, expert-driven interpretation to extract biologically meaningful insights. Here, we introduce (cointelligent single-cell spatial cell‒cell communication: iS2C2), a novel cointelligent platform that synergizes mathematically rigorous computational algorithms with the contextual reasoning capabilities of LLMs to …

The Influence Of Prosthetic Obturators On Quality Of Life In Individuals With Maxillectomy Defects, Minseok Kim

Oral Health

Abstract

Introduction: In recent years, there has been a growing focus on understanding the impact of oral cancer on patients' quality of life. Prosthetic rehabilitation techniques, such as maxillary obturators, often in conjunction with reconstructive surgery, have emerged as interventions to address the challenges posed by post-maxillectomy abnormalities.

Objective: This study aims to systematically review and evaluate the effectiveness of maxillofacial prosthetic rehabilitation using obturators in enhancing the quality of life of patients following maxillectomy.

Methodology: Systematic review of identified literature spanning the timeframe from 2000 to 2020 was used. The comprehensive search encompassed widely recognized databases including PubMed, …

How Screen Time Affects Language Development In Children Ages Three To Five Years, Alyssa R. Sherman

Honors Thesis

Screen time has become an increasingly prominent part of early childhood, particularly following shifts in daily routines after the COVID-19 pandemic. This literature review examines how screen time affects language development in children ages three to five, a critical developmental period for expressive and receptive language skills. The review synthesizes current research on the use of passive and interactive screens and their associations with language acquisition, cognitive development, social communication, and physical health outcomes. Across studies, a consistent pattern emerges: excessive screen time is strongly associated with delayed language milestones, reduced social communication skills, poorer sleep quality, and increased physical …