Digital Commons Network^™

Naturify 2300, Yarina Yiwei Dai

Masters Theses

In my art practice, I explore the interplay between human desires to manipulate and anthropomorphize nature, as seen in the technological augmentation of plants and living entities. This investigation delves into how this intersection, alongside empathy towards these creations, contributes to fears of uncontrollability and the risks of addiction and excessive dependence on technology.

Bioengineering and genetic modification have cultivated unprecedented developments, allowing humans to manipulate the fundamental building blocks of life. My research speculates on this technology further, modifying the genetic code of organisms and creating bioengineered wearable entities with enhanced traits or entirely new functionalities. The primary objective …

Forecasting Acute Kidney Injury And Resource Utilization In Icu Patients Using Longitudinal, Multimodal Models, Yukun Tan, Merve Dede, Vakul Mohanty, Jinzhuang Dou, Holly Hill, Elmer Bernstam, Ken Chen

Faculty, Staff and Student Publications

Background: Advances in artificial intelligence (AI) have realized the potential of revolutionizing healthcare, such as predicting disease progression via longitudinal inspection of Electronic Health Records (EHRs) and lab tests from patients admitted to Intensive Care Units (ICU). Although substantial literature exists addressing broad subjects, including the prediction of mortality, length-of-stay, and readmission, studies focusing on forecasting Acute Kidney Injury (AKI), specifically dialysis anticipation like Continuous Renal Replacement Therapy (CRRT) are scarce. The technicality of how to implement AI remains elusive.

Objective: This study aims to elucidate the important factors and methods that are required to develop effective predictive models of …

Validation Of Harmonized Cognitive Assessment Protocol (Hcap) In Egypt: A Sub Study Of The Egyptian Longitudinal Study Of Aging (Al-Seha), Sara Ayman Moustafa

Theses and Dissertations

Abstract Building upon the insights gained from the AL-SEHA pilot study, which underscored the pressing need for comprehensive cognitive assessment tools in Egypt, a subsequent research initiative was launched. This initiative sought to address the escalating burden of dementia and Alzheimer's Disease Related Dementias (ADRD) by adapting and validating the Harmonized Cognitive Assessment Protocol (HCAP) for the Egyptian context. The validation study, conducted with 300 participants aged 55 and over, drawn from diverse backgrounds and healthcare settings in Cairo, Mansoura, and Beni Suef, demonstrated the HCAP's effectiveness across different age and education levels within the Egyptian population. The tool exhibited …

Improving Access To Exome Sequencing In A Medically Underserved Population Through The Texome Project, Blake Vuocolo, Ryan J German, Seema R Lalani, Chaya N Murali, Carlos A Bacino, Stephanie Baskin, Rebecca Littlejohn, John D Odom, Scott Mclean, Carrie Schmid, Morgan Nutter, Melissa Stuebben, Emily Magness, Olivia Juarez, Dina El Achi, Bailey Mitchell, Kevin E Glinton, Laurie Robak, Sandesh C S Nagamani, Lisa Saba, Adasia Ritenour, Lilei Zhang, Haley Streff, Katie Chan, K Jordan Kemere, Kent Carter, Texome Project, Nichole Owen, Liesbeth Vossaert, Pengfei Liu, Hugo Bellen, Michael F Wangler

Faculty, Staff and Students Publications

PURPOSE: Genomic medicine can end diagnostic odysseys for patients with complex phenotypes; however, limitations in insurance coverage and other systemic barriers preclude individuals from accessing comprehensive genetics evaluation and testing.

METHODS: The Texome Project is a 4-year study that reduces barriers to genomic testing for individuals from underserved and underrepresented populations. Participants with undiagnosed, rare diseases who have financial barriers to obtaining exome sequencing (ES) clinically are enrolled in the Texome Project.

RESULTS: We highlight the Texome Project process and describe the outcomes of the first 60 ES results for study participants. Participants received a genetic evaluation, ES, and return …

The 2022 Symposium On Dementia And Brain Aging In Low- And Middle-Income Countries: Highlights On Research, Diagnosis, Care, And Impact, Raj N. Kalaria, Gladys Maestre, Simin Mahinrad, Daisy Acosta, Rufus Akinyemi, Suvarna Alladi, Ricardo F. Allegri, Faheem Arshad, David Oluwasayo Babalola, Noe Garza

School of Medicine Publications

Two of every three persons living with dementia reside in low- and middle-income countries (LMICs). The projected increase in global dementia rates is expected to affect LMICs disproportionately. However, the majority of global dementia care costs occur in high-income countries (HICs), with dementia research predominantly focusing on HICs. This imbalance necessitates LMIC-focused research to ensure that characterization of dementia accurately reflects the involvement and specificities of diverse populations. Development of effective preventive, diagnostic, and therapeutic approaches for dementia in LMICs requires targeted, personalized, and harmonized efforts. Our article represents timely discussions at the 2022 Symposium on Dementia and Brain Aging …

Measurement Invariance Of The Pandemic Anxiety Inventory In Different Demographic Groups, Irvin Sam Schonfeld, Tasmyn Prytherch, Mark Cropley, Jay Verkuilen, Renzo Bianchi

Publications and Research

Background The Pandemic Anxiety Inventory (PAI) was developed in the context of the COVID-19 pandemic. Its content allows it to assess anxiety in connection to any pandemic. Previous research has demonstrated the instrument’s reliability and validity. An important question for clinicians and researchers, however, remains open: Does the PAI have similar meaning for members of different demographic groups? The finding of measurement invariance would allow clinicians and researchers to comparatively assess pandemic-related anxiety across demographic groups, including favored and disfavored groups.

Methods We conducted a multi-group confirmatory factor analysis to assess the measurement invariance of the PAI using data obtained …

Flanker Task Performance In Young And Older Adults: A Behavioral And Erp Study, Fatima Medrano

Dissertations, Theses, and Capstone Projects

Research suggests that as we get older, executive function abilities decline (Hasher & Zacks, 1988; Salthouse, 1996). One affected ability is that of inhibitory control, which aids in monitoring our responses to non-target stimuli or information. Current research on inhibition reveals inconsistencies across studies. Monitoring brain responses during the Flanker (used to measure inhibitory control) task may add valuable insight into the processes underlying group differences behaviorally, by studying the N200 and P300 event-related potentials which have been associated with inhibitory control processes. This study investigated whether there are differences between older and younger adults in inhibitory control and whether …

Articulatory Activity Of The Tongue, Jaw, And Lips During The Second Passaggio Transition Of The Soprano Voice, Richard C. Lissemore

Dissertations, Theses, and Capstone Projects

This dissertation describes three experiments designed to explore the acoustic and articulatory activity of a perceptible change in the soprano voice known as the secondo passaggio, or second transition, which typically occurs for the [ɑ] vowel between D♮5 (587 Hz) and F♮5 (698 Hz). Acoustically, the transition involves a shift in resonance strategy from second resonance tracking of the second harmonic (f_R2/2f_o) to first resonance tracking of the fundamental frequency (f_R1/f_o). To quantify the acoustics of the transition, we employed the measure L₁-L₂, the …

Determining Factors For Improved Uptake Of Harm Reduction Services In The United States: A Study Of Inclusive, Culturally Sensitive Messaging, Lauretta Ekanem Omale

Dissertations

Harm reduction refers to public health policies and programs aimed at decreasing the adverse consequences associated with drug use. While harm reduction services (e.g., syringe exchange programs) can mitigate health risks, marginalized groups face barriers to service access and utilization, partially due to ineffective messaging approaches that fail to align with cultural values and experiences. A one-size-fits-all approach to messaging can negatively impact service utilization, health outcomes, and health disparities. Ineffective communication can lead to poor adherence to treatment, poorer health outcomes, and increased adverse events.

Culturally insensitive communication contributes to stigma, mistrust, and lack of perceived relevance, discouraging service …

A Mixed-Method Analysis Of The Contribution Of Informal Sport To Public Health In Australia, Ruth Jeanes, Justen O'Connor, Dawn Penney, Ramon Spaaij, Jonathan Magee, Eibhlish O' Hara, Lisa Lymbery

Research outputs 2022 to 2026

Informal sport is a growth area of sport participation but there has been limited examination of how informal and unstructured forms of participation may contribute to health outcomes that are important for public health. This article aims to address the current lack of data examining the health outcomes associated with informal sport participation and consider the potential role of informal sport within efforts to promote healthier communities through sport. The article seeks to broaden understanding of how informal sport participation can contribute to health outcomes, particularly with regard to increasing physical activity and enhancing mental health and social connection. The …

Exploring Counseling Self-Efficacy Development Among Graduate Speech-Language Pathology Students, Rebecca Jones

Dissertations, 2020-current

Two thematically linked studies are contained within this dissertation document, completed in partial fulfillment of the degree requirements for the Doctor of Philosophy, per the Communication Sciences and Disorders Ph.D. handbook, and in agreement with an advisory committee. These projects serve to advance the scholarship of teaching and learning in the areas of counseling skill development and therapeutic alliance building. The first study deals with the impact of a university-based caregiver coaching program on SLP graduate students' counseling self-efficacy (CSE) and their perceptions of therapeutic alliances with infant caregivers. A mixed-methods approach was employed utilizing reflexive thematic analysis (RTA) and …

Conceptualizing Recovery From Mental Illness In Indonesia: A Scoping Review, Flora Cohen, Agus Sugianto, Hans Pols, Clement Bayetti

Makara Human Behavior Studies in Asia

Understanding how recovery is defined and realized across different cultural contexts is vital to upholding the dignity and rights of people with mental illnesses. Within the Indonesian context, there is a dearth of research on conceptualizations of recovery from mental illnesses. Questions remain regarding the extent to which service users and providers share common definitions of recovery. We conducted a scoping review to interrogate current definitions of recovery from the perspectives of the various actors working with people with lived experiences of mental illness and extreme mental distress. We found that definitions of recovery differ across multiple domains and include …

Optimizing Social Determinant Of Health Concept Extraction, Niharika Singh

Theses

Generative Artificial Intelligence has recently garnered enormous attention for a varied number of reasons, one of them being its capacity to automate complex tasks. As the potential for integrating Generative Artificial Intelligence across technology, media, and healthcare grows, many tasks previously reliant on manual or algorithm-intensive methods can be simplified significantly. One such challenge is concept extraction, which is a labor-intensive process, especially when performed manually for building robust ontologies. It involves analyzing text to identify and extract relevant concepts, key phrases, entities, and relationships between these entities. This thesis explores various challenges of concept extraction from the ABCD (Adolescent …

Examining The Association Of Type 2 Diabetes Mellitus Risk Factors Between African Immigrants Living In The United States And African Americans Born In The United States, Philip Effiong

Walden Dissertations and Doctoral Studies

The purpose of the study was to investigate the risk factors for Type 2 diabetes mellitus (T2DM) among African immigrants and African Americans born in the United States to identify differences and similarities in their impact and prevalence. Variables considered as potential differentiators included alcohol consumption, income, educational levels, and smoking habits, age, and gender. The health belief model served as the theoretical framework. Utilizing data from the National Health and Nutrition Examination Survey 2015-2016, logistic regression analyses were used to test for significant factors affecting T2DM prevalence in these groups. Results indicated that country of origin did not predict …

Innovation In Bioinformatics: Recent Tools, Database And Involvement Of Artificial Intelligence, Aziz Ahmed, Mohd Shuaib, Abdulbasid Banga, Rizwan Ahmad

Indonesian Journal of Medical Chemistry and Bioinformatics

Bioinformatics has evolved in recent years into a crucial subject and a well-liked research area that is interconnected with many approaches and disciplines. The capacity of bioinformatics and its approaches to tackle challenging biological problems and promote research and development. There are various tools and database which are used in bioinformatics. AI is the capacity of a computational system to carry out various activities associated with intellectual beings and as a computer system's imitation of human intelligence processes. The bioinformatics applications with artificial intelligence have the capacity to annotate the data in the direction of logical conclusions. By combining AI …

Latinas In The United States Facing Healthcare Access Challenges In A Mid-Size Urban Community, Nathan M. Lee, Deborah Kessler

Journal of Global Awareness

This study examines the discrepancies and underlying factors in access to healthcare resources regarding breast and cervical cancer for Latinas in a mid-sized urban midwestern community. A survey was conducted at clinics hosted by a local non-profit organization, and forty participants completed surveys for this study (n=40). Bivariate correlation analysis in SPSS determined that significant positive correlations were found between the subjects’ knowledge of the signs and symptoms of cervical cancer and their knowledge of the recommended frequency of receiving pap smears (p

Lived Experiences Of Quality Of Life Among Makonde Immigrants In Kenya During And After The Covid-19 Pandemic, Shem Migosi Kenyanya

Walden Dissertations and Doctoral Studies

The COVID-19 pandemic affected Makonde immigrants’ health and quality of life around the world more than any other previous event. This descriptive qualitative study aimed to contribute knowledge and understanding of the lived experiences of Makonde immigrants and their health and quality of life during and after the COVID-19 pandemic. Shye’s systematic quality of life model served as the theoretical basis for the study, along with Wilson and Cleary’s conceptual model of health quality of life. Semi-structured interviews were conducted with ten participants recruited through social media and flyers posted in Kilifi and Kwale counties. Subjects were interviewed face-to-face and …

Differences In Immigrant And U.S. Native Born Patients’ Experiences In The American Healthcare System: A Correlational Study, Betaneya W. Daniel

Virginia Journal of Public Health

Objective: To examine any perceived barriers that might exist in the United States healthcare system and gather data on how different patients experience the system.

Methods: The study utilized a correlational analysis with usage of a Likert scale survey administered to U.S.- born natives, immigrants, and healthcare providers. The survey assessed respondents of their access to healthcare services, barriers to healthcare services, healthcare provider trust/relationships, and health institutions’ relations. Another survey assessed healthcare providers’ belief in the efficacy of their services and health institutions’.

Results: No statistically significant differences were found between U.S. natives and immigrants, but notable distinctions were …

Health Equity: Communicating Impaired Water Status, Emily Potter

Virginia Journal of Public Health

Introduction: Land use changes in the Rivanna River and James River Watersheds have increased the number of impaired recreational waters, and there is a disparity in the equitable communication of these impairments to different populations. Ineffective communication contributes to inequities in access to safe, accessible, and affordable water for vulnerable populations, placing public health at risk.

Methods: This study uses secondary data from the Environmental Protection Agency’s Watershed Index Online (WSIO) Indicator Data Tables, Virginia Department of Environmental Quality (DEQ), Rivanna River Association, and James River Association. Correlations, linear regression, and percent change were used to identify statistically significant trends …

Hearing Loss And Cognitive Decline In The Aging Population: Emerging Perspectives In Audiology, Naveen K. Nagaraj

Communicative Disorders and Deaf Education Faculty Publications

In this perspective article, the author explores the connections between hearing loss, central auditory processing, and cognitive decline, offering insights into the complex dynamics at play. Drawing upon a range of studies, the relationship between age-related central auditory processing disorders and Alzheimer’s disease is discussed, with the aim of enhancing our understanding of these interconnected conditions. Highlighting the evolving significance of audiologists in the dual management of cognitive health and hearing impairments, the author focuses on their role in identifying early signs of cognitive impairment and evaluates various cognitive screening tools used in this context. The discussion extends to adaptations …

Health Equity Engineering: Optimizing Hope For A New Generation Of Healthcare, Felicity T Enders, Joyce E Balls-Berry, Et Al.

2020-Current year OA Pubs

Medical researchers are increasingly prioritizing the inclusion of underserved communities in clinical studies. However, mere inclusion is not enough. People from underserved communities frequently experience chronic stress that may lead to accelerated biological aging and early morbidity and mortality. It is our hope and intent that the medical community come together to engineer improved health outcomes for vulnerable populations. Here, we introduce Health Equity Engineering (HEE), a comprehensive scientific framework to guide research on the development of tools to identify individuals at risk of poor health outcomes due to chronic stress, the integration of these tools within existing healthcare system …

Faith-Based Intervention To Prevent Adolescent Self-Injury: An Integrative Review, Adekemi O. Akinyemi

Doctoral Dissertations and Projects

This integrative review explores the efficacy of incorporating faith-based (Christian/spiritual) interventions within the framework of Dialectical Behavior Therapy (DBT) to prevent non-suicidal self-injury (NSSI) among adolescents aged 11-19. As the prevalence of NSSI among this demographic group continues to rise, understanding the potential benefits and challenges of integrating faith-based components into evidence-based therapeutic approaches is crucial. The review synthesizes existing literature, drawing on empirical studies, theoretical frameworks, and clinical evidence to assess the impact of faith-based integration in DBT. Through a comprehensive analysis of diverse sources (e.g. CINAHL, PubMed, PsycINFO, NIH) this review was able to shed light on the …

A Microcosting Approach For Planning And Implementing Community-Based Mental Health Prevention Program: What Does It Cost?, Sharmily Roy, Henry Shelton Brown, Lisa Sanger Blinn, Sarah Carter Narendorf, Jane E Hamilton

Faculty, Staff and Student Publications

BACKGROUND: Estimating program costs when planning community-based mental health programs can be burdensome. Our aim was to retrospectively document the cost for the first year of planning and implementing Healthy Minds Healthy Communities (HMHC), a mental health promotion and prevention multi-level intervention initiative. This Program is among the first to use the Community Initiated Care (CIC) model in the US and is aimed at building community resilience and the capacity for communities to provide mental health support, particularly among those disproportionately impacted by COVID-19. Our objective is to share our methods for costing a program targeting 10 zip codes that …

A Microcosting Approach For Planning And Implementing Community-Based Mental Health Prevention Program: What Does It Cost?, Sharmily Roy, Henry Shelton Brown, Lisa Sanger Blinn, Sarah Carter Narendorf, Jane E Hamilton

Faculty, Staff and Student Publications

BACKGROUND: Estimating program costs when planning community-based mental health programs can be burdensome. Our aim was to retrospectively document the cost for the first year of planning and implementing Healthy Minds Healthy Communities (HMHC), a mental health promotion and prevention multi-level intervention initiative. This Program is among the first to use the Community Initiated Care (CIC) model in the US and is aimed at building community resilience and the capacity for communities to provide mental health support, particularly among those disproportionately impacted by COVID-19. Our objective is to share our methods for costing a program targeting 10 zip codes that …

Generalizing Parkinson’S Disease Detection Using Keystroke Dynamics: A Self-Supervised Approach, Shikha Tripathi, Alejandro Acien, Ashley A Holmes, Teresa Arroyo-Gallego, Luca Giancardo

Faculty, Staff and Student Publications

Objective: Passive monitoring of touchscreen interactions generates keystroke dynamic signals that can be used to detect and track neurological conditions such as Parkinson's disease (PD) and psychomotor impairment with minimal burden on the user. However, this typically requires datasets with clinically confirmed labels collected in standardized environments, which is challenging, especially for a large subject pool. This study validates the efficacy of a self-supervised learning method in reducing the reliance on labels and evaluates its generalizability.

Materials and methods: We propose a new type of self-supervised loss combining Barlow Twins loss, which attempts to create similar feature representations with reduced …

Empowering Personalized Pharmacogenomics With Generative Ai Solutions, Mullai Murugan, Bo Yuan, Eric Venner, Christie M Ballantyne, Katherine M Robinson, James C Coons, Liwen Wang, Philip E Empey, Richard A Gibbs

Faculty, Staff and Students Publications

Objective: This study evaluates an AI assistant developed using OpenAI's GPT-4 for interpreting pharmacogenomic (PGx) testing results, aiming to improve decision-making and knowledge sharing in clinical genetics and to enhance patient care with equitable access.

Materials and methods: The AI assistant employs retrieval-augmented generation (RAG), which combines retrieval and generative techniques, by harnessing a knowledge base (KB) that comprises data from the Clinical Pharmacogenetics Implementation Consortium (CPIC). It uses context-aware GPT-4 to generate tailored responses to user queries from this KB, further refined through prompt engineering and guardrails.

Results: Evaluated against a specialized PGx question catalog, the AI assistant showed …

Playing With International Students From Asia: An Exploration Of Cultural Commonalities And Differences In Developmental Transformations (Dvt), Hazuki Okamoto

Expressive Therapies Capstone Theses

Asian international students in the United States face a multitude of challenges such as language barriers, differences in cultural norms and behaviors, and identity confusion while navigating a foreign landscape. Developmental Transformations (DvT), a form of drama therapy, may apply to these challenges by enabling participants to explore different identities and express themselves creatively beyond the language barrier. This community engagement project was designed for Asian international students to be seen and heard by utilizing DvT. Within an in-person workshop, five participants played with their shared stories, and explored international and cultural roles in group DvT. Key takeaways from the …

Exploring Hispanic Immigrant Parents Literacy Needs In Navigating Life With Children In The United States, Michelle Lowry

Seton Hall University Dissertations and Theses (ETDs)

The responsibility of raising a child is demanding on all parents, but immigrant parents with limited literacy skills in English may find parenting even more demanding than native born parents. Hispanic immigrant parents are rarely consulted about their literacy needs. Furthermore, they are often overlooked as experts on their own needs. Using two of the most widely accepted models of literacy, The Simple View of Writing and The Simple View of Reading, this study explored Hispanic immigrant parents' literacy needs in the United States. The current study was conducted on N=30 Hispanic Immigrant parents, ages early 30s to mid 70s. …

Using The Motivated Information Management Theory And The Social Support Theory To Understand Caregiver Perspectives Of Currently Available Health Communication Regarding Dementia: A Qualitative Study, Sara J. Alig

Doctoral Dissertations and Projects

Dementia brings a cascade of changes into the life of not only the person facing it, but also the lives of the supporting family and caregivers. Dementia manifests with a gradual decline, or in some cases, a variably progressive decline in cognitive abilities. This decline requires the individual to rely more and more on caregivers. Caregiving necessitates the giving of oneself for another’s sake and oftentimes results in negative physical and social-emotional side effects. To navigate through the changes that are happening to their loved ones, as well as to themselves, caregivers need educational and social support. The purpose of …

Addressing Mental Health In Young Adults: A Modern Approach Compared To Previous Generations, Breeha A. Shah

DePaul Journal of Health Care Law

The escalating prevalence of mental health issues among today's young adults underscores the vital importance of addressing mental health in the pursuit of public health objectives. In response to this, The House Education and Labor Committee issued a report on the Mental Health Services for Students Act of 2020 (the Act), to amend the Public Health Service Act relating to school children. This revision seeks to bolster the support for students and young people by ensuring their access to comprehensive mental health programs within the school environment. The Act recognizes that safeguarding mental health is an immediate concern for public …