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Healthnet News V.16:No.2 Summer 2001, Judith S. Kronick, Alberta Richetelle

Articles - Patient Care

A newsletter for public librarians and others interested in consumer health information services

What's Happening: June 20, 2001, Maine Medical Center

What's Happening

No abstract provided.

The Outbreak Of West Nile Virus Infection In The New York City Area In 1999, Denis Nash, Farzad Mostashari, Annie Fine, James Miller, Daniel O'Leary, Kristy Murray, Ada Huang, Amy Rosenberg, Abby Greenberg, Margaret Sherman, Susan Wong, Marcelle Layton

Publications and Research

Background In late August 1999, an unusual cluster of cases of meningoencephalitis associated with muscle weakness was reported to the New York City Department of Health. The initial epidemiologic and environmental investigations suggested an arboviral cause.

Methods Active surveillance was implemented to identify patients hospitalized with viral encephalitis and meningitis. Cerebrospinal fluid, serum, and tissue specimens from patients with suspected cases underwent serologic and viral testing for evidence of arboviral infection.

Results Outbreak surveillance identified 59 patients who were hospitalized with West Nile virus infection in the New York City area during August and September of 1999. The median age …

Effects Of Professional Interpreter Services On The Utilization Of Health Care Services Of Different Language/Cultural Groups, Amanda Fleming Petrik

Dissertations and Theses

Immigration has affected the number of U.S. residents who speak little or no English. These residents have limited English proficiency. Research studies have indicated discrepancies in medical interpretation and medical care. However, differences in health care between the language/ cultural groups are rarely recognized as health discrepancies.

This research project is a quasi-experimental design, testing differences between the four major language groups in the greater Portland, Oregon area. These four major language/cultural groups speak Chinese, Vietnamese, Spanish and Russian.

A secondary data analysis was used to compare the differences in utilization of emergency room services, routine services, and urgent care …

Commencement, Philadelphia (2001), Philadelphia College Of Osteopathic Medicine

Commencements

Philadelphia Campus D.O. Commencement Program, 110th Class. Degrees include Doctor of Osteopathic Medicine.

Commencement Speaker: The Honorable Ruth Ann Minner, Governor of Delaware

Effect Of Relaxation On Neuro-Immune Responses Of Persons Undergoing Chemotherapy, Patricia K. Taylor Pothier Phd, Ms, Rn

Dissertations

Chemotherapy can be considered both a physiologic and a psychological stressor. Anxiety, nausea, emesis, and immunosuppression are commonly associated with chemotherapy, and may adversely affect the outcome or the process of treatment. Chemotherapy-related anxiety can exacerbate negative side-effects. Some psychological stressors, such as anxiety, can result in down-regulation of certain immune functions. Studies have demonstrated that behavioral interventions, such as specific relaxation strategies, can modify stress-related immune modulation. These behavioral interventions have also been shown to decrease the degree of nausea and vomiting associated with chemotherapy. The purpose of this study was to examine whether a relaxation intervention would result …

Commencement Program 2001, Loma Linda University

Commencement Programs

CONTENTS

2 | 2001 Events of Commencement

3 | The Academic Procession

4 | The Speakers

10 | The University Honorees

18 | The School Honorees

26 | The Programs

• School of Medicine, 27
• School of Dentistry, 34
• Graduate School, 42
• School of Nursing, 51
• School of Allied Health Professions - Physical Therapy, 56
• School of Allied Health Professions, 63
• School of Public Health, 71

Effect Of A Single Amino Acid Change In Mhc Class I Molecules On The Rate Of Progression To Aids, Xiaojiang Gao, George W. Nelson, Peter Karacki, Maureen P. Martin, John Phair, Richard A. Kaslow, James J. Goedert, Susan Buchbinder, Keith Hoots, David Vlahov, Stephen J. O'Brien, Mary Carrington

Biology Faculty Articles

Background From studies of genetic polymorphisms and the rate of progression from human immunodeficiency virus type 1 (HIV-1) infection to the acquired immunodeficiency syndrome (AIDS), it appears that the strongest susceptibility is conferred by the major-histocompatibility-complex (MHC) class I type HLA-B*35,Cw*04 allele. However, cytotoxic T-lymphocyte responses have been observed against HIV-1 epitopes presented by HLA-B*3501, the most common HLA-B*35 subtype. We examined subtypes of HLA-B*35 in five cohorts and analyzed the relation of structural differences between HLA-B*35 subtypes to the risk of progression to AIDS. Methods Genotyping of HLA class I loci was performed for 850 patients who seroconverted and …

Icam-1 Transmembrane Signaling: Involvement Of Taxreb107 In Icam-1-Mediated Signal Transduction, Brian Lee

Yale Medicine Thesis Digital Library

The role of membrane ICAM-1 in intercellular adhesion, through interaction with the leukocyte beta2 integrin receptors LFA-1 and Mac-1, is well established. However, until recently, ICAM-1 was widely regarded as being simply an "anchor" molecule, promoting, for example, firm adhesion of lymphocytes to vascular endothelial cells. The demonstration that ICAM-1 is connected to the actin-based cytoskeleton through interactions with subcortical actin-binding proteins, such as alpha-actinin, enhanced this concept. However, ICAM-1 has been increasingly shown to have signaling properties of its own. Engagement of ICAM-1 extracellularly, either through its natural counter-receptors, LFA-1/Mac-1, or through antibody mediated clustering, can produce numerous changes …

Clumping Factor A Mediates Binding Of Staphylococcus Aureus To Human Platelets, Ian R. Siboo, Ambrose L. Cheung, Arnold S. Bayer, Paul M. Sullam

Dartmouth Scholarship

The direct binding of bacteria to platelets may be an important virulence mechanism in the pathogenesis of infective endocarditis. We have previously described Staphylococcus aureus strain PS12, a Tn551-derived mutant of strain ISP479, with reduced ability to bind human platelets in vitro. When tested in an animal model of endocarditis, the PS12 strain was less virulent than its parental strain, as measured by bacterial densities in endocardial vegetations and incidence of systemic embolization. We have now characterized the gene disrupted in PS12 and its function in platelet binding. DNA sequencing, Southern blotting, and PCR analysis indicate that PS12 contained two …

Morphine Enhances The Permeability Across Vascular Endothelial Cell Barriers, Jenine Anday

Seton Hall University Dissertations and Theses (ETDs)

Using three types of in vitro endothelial cell barrier models, we investigated the direct effects and mechanisms of morphine on vascular permeability. Our current studies illustrate LPS induces permeability across these VEC barriers, and is significantly enhanced when co-treated with morphine, displayed using the [ 14 CJ-inulin paracellular marker. Incubation with morphine alone induces permeability in a concentration­ depeodent manner, and is not blocked by the addition of naloxone. Morphine enhances the detrimental effects of LPS on cell viability and alone also decreases endothelial cell viability, concentration-dependently, which is also not affected by naloxone, as demonstrated by the trypan blue …

Evidence For Two Mechanisms Of Amino Acid Osmolyte Release From Hippocampal Slices, R. Franco, M. E. Torres-Marquez, H. Pasantes-Morales

School of Veterinary and Biomedical Sciences: Faculty Publications

A 30% decrease in osmolarity stimulated ³H-taurine, ³H-GABA and glutamate (followed as ³H-D-aspartate) efflux from rat hippocampal slices. ³H-taurine efflux was activated rapidly but inactivated slowly. It was decreased markedly by 100 μM 5-nitro-(3-phenylpropylamino) benzoic acid (NPPB) and 600 μM niflumic acid and inhibited strongly by tyrphostins AG18, AG879 and AG112 (25–100 μM), suggesting a tyrosine kinase-mediated mechanism. Hyposmolarity activated the mitogen-activated protein kinases (MAPK) extracellular-signal-related kinase-1/2 (ERK1/ERK2) and p38, but blockade of this reaction did not affect ³H-taurine efflux. Hyposmosis also activated phosphatidyl-inositide 3-kinase (PI3K) and its prevention by wortmannin (100 nM) essentially abolished …

Capitalism And The Value Of Life: Foot-And-Mouth And The Culling Of Herds, Ibpp Editor

International Bulletin of Political Psychology

This article describes some psychological implications of culling as an intervention to help combat the spread of foot-and-mouth disease.

How Peruvian Mothers Appraise Pneumonia And The Predictors Of Their Intention To Seek Medical Care When Their Children Have Signs Of Pneumonia, César Augusto Gálvez

Loma Linda University Electronic Theses, Dissertations & Projects

Pneumonia ranks first in health problems demanding attention, and second in the cause of mortality for children under five years old in Peru (Toledo, & Minaya, 1999). Studies about behavioral determinants that influence mothers to seek medical help for their child with signs of pneumonia do not focus on the contribution of the behavioral determinants to intention of seeking medical help.

Using the Theory of Planned Behavior (TPB) and a cross-sectional design, the objectives of this study were to know first, Peruvian mothers' perceptions about knowledge and recognition of pneumonia, and about the government pneumonia campaign (GPC). Second, mothers' attitudes, …

Sars, A Sara Homolog Repressible By Agr, Is An Activator Of Protein A Synthesis In Staphylococcus Aureus, Ambrose L. Cheung, Katherine Schmidt, Brian Bateman, Adhar C. Manna

Dartmouth Scholarship

The expression of protein A (spa) is repressed by global regulatory loci sarA and agr. Although SarA may directly bind to the spa promoter to downregulate spa expression, the mechanism by which agr represses spa expression is not clearly understood. In searching for SarA homologs in the partially released genome, we found a SarA homolog, encoding a 250-amino-acid protein designated SarS, upstream of the spa gene. The expression of sarS was almost undetectable in parental strain RN6390 but was highly expressed in agr and sarA mutants, strains normally expressing high level of protein A. Interestingly, protein A …

Investigations Into The Innate Resistance Of The Tick, Dermacentor Variabilis, When Challenged With The Bacterium, Escherichia Coli, Shane Michael Ceraul

Biological Sciences Theses & Dissertations

In addition to the soluble response, many invertebrates control bacterial infections by means of phagocytosis or melanotic encapsulation. In some insects, Escherichia coli growth is reported to be inhibited by aggregation/encapsulation. Soluble and phagocytic responses to bacterial challenge have been reported in ticks, but evidence of an aggregation/encapsulation response was reported only for inanimate (araldite) implants. This study was done to determine how ticks control infection by E. coli. Ticks were challenged by direct inoculation of bacteria into the hemocoel cavity. Using plate counts, no viable E. coli were detected I hour post-inoculation. A direct fluorescence assay (DF A) …

Trends. The Psycho-Politics Of Foot In Mouth On Foot In Mouth: Pigs, Sheep, Cows, Politicians On The Animal Farm, Ibpp Editor

International Bulletin of Political Psychology

This article discusses agricultural policy in the United Kingdom regarding foot and mouth disease of cloven-hoofed animals.

Review Of: Dangerous Places: Health, Safety, And Archaeology (David A. Poirer & Kenneth L. Feder Eds.), Natalie Duval

RISK: Health, Safety & Environment (1990-2002)

Review of the book: Dangerous Places: Health, Safety, and Archaeology (David A. Poirier& Kenneth L. Feder eds., Bergin & Garvey, Greenwood Publishing Group, Inc. 2001). Introduction, bibliographic references, index. ISBN0-89789-632-7 [264 pp. $65.00. Cloth, 88 Post Road West, P.O. Box5007, Westport, CT 06881-5007.

Crossing Myriad Borders: A Dimensional Analysis Of The Migration And Health Experiences Of Indigenous Oaxacan Women, Sharon Mcguire Phd, Op, Msn, Rn-C

Dissertations

The growing feminization of the migration of ethnic indigenous women, such as Mixtecs, Zapotecs and Triquis from the southern Mexican state of Oaxaca, are altering the dynamics and configuration of traditional Mexican migration, making it especially significant for the health professions. Informed by a postcolonial ecofeminist paradigm, this bi-national grounded theory study explored the migration and health experiences of indigenous Oaxacan immigrant/migrant women. Data collection using participant observation and interviewing occurred in Oaxaca, Mexico, along the US-Mexico border, and the interior of California. Dimensional analysis was used as the method of data analysis to generate theoretical understandings of these phenomena. …

Jefferson Alumni Bulletin – Volume 50, Number 2, March 2001

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume 50, Number 2, March 2001 Tom Nasca’75 in appointed Dean, page 4 Hospital for neuroscience is created in wills building, page 5 Key molecular pathway in apoptosis, page 8 Swallowing a gene to treat or prevent Cancer? Page 9 “He served Jefferson during difficult times”, page 10 Gardner, Keeley, Slogoff are nominees for trustee, page 21

Vital Signs, Spring 2001, Boonshoft School Of Medicine

Vital Signs

A twenty-one page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes feature articles, student notes, and more.

Maternal Deaths In A Developing Country: A Study From The Aga Khan University Hospital, Karachi, Pakistan 1988-1999, R N. Qureshi, S Jaleel, R Hamid, S F. Lakha

Department of Obstetrics & Gynaecology

Objective: The maternal deaths occurring over a twelve-year period (1988-1999) in a tertiary referral center were reviewed. The purpose of the study was to assess the causes of these maternal deaths.
Setting: The Aga Khan University Hospital (AKUH) Karachi, Pakistan.
Methods: The medical records of maternal deaths were reviewed. These were women who had either registered for delivery at the hospital; or were referred from another hospital or from home, when an emergency developed. They were either admitted to the Medicine, Surgery and the Obstetrics and Gynaecology Departments at the hospital.Results: A total of 81 maternal deaths were identified, of …

Golden Eggs: Towards The Rational Regulation Of Oocyte Donation, Kenneth Baum

BYU Law Review

No abstract provided.

A Peculiar Logic Of Pro-Abortion Advocacy, Ibpp Editor

International Bulletin of Political Psychology

This article identifies a weakness in pro-abortion advocacy and how this weakness can be resolved to support said advocacy.

How Can Health Serve As A Bridge For Peace? Certi Crisis And Transition Tool Kit, Rosalia Rodriguez-Garcia, James Macinko, F. Xavier Solorzano, Marita Schlesser, George Washington University School Of Public Health And Health Services

Global Health Faculty Publications

No abstract provided.

Characterization Of Sarr, A Modulator Of Sar Expression In Staphylococcus Aureus, Adhar Manna, Ambrose L. Cheung

Dartmouth Scholarship

The expression of virulence determinants in Staphylococcus aureus is controlled by global regulatory loci (e.g., sar and agr). The sar locus is composed of three overlapping transcripts (sar P1, P3, and P2 transcripts from P1, P3, and P2 promoters, respectively), all encoding the 372-bp sarA gene. The level of SarA, the major regulatory protein, is partially controlled by the differential activation of sar promoters. We previously partially purified a ∼12 kDa protein with a DNA-specific column

Comparison Of Two Azithromycin Distribution Strategies For Controlling Trachoma In Nepal, Susan Osaki Holm, Hem C. Jha, Ramesh C. Bhatta, J.S. P. Chaudhary, B. B. Thapa, Dale Davis, Ram Prasad Pokhrel, Miao Yinghui, Michael Zegans, Julius Schachter, Kevin D. Frick, Lisa Tapert, Thomas M. Leitman

Dartmouth Scholarship

OBJECTIVE:

The study compares the effectiveness of two strategies for distributing azithromycin in an area with mild-to-moderate active trachoma in Nepal.

METHODS:

The two strategies investigated were the use of azithromycin for 1) mass treatment of all children, or 2) targeted treatment of only those children who were found to be clinically active, as well as all members of their household.

FINDINGS:

Mass treatment of children was slightly more effective in terms of decreasing the prevalence of clinically active trachoma (estimated by clinical examination) and of chlamydial infection (estimated by DNA amplification tests), although neither result was statistically significant.

CONCLUSION: …

What's Happening: January 31, 2001, Maine Medical Center

What's Happening

No abstract provided.

Ada News - 01/08/2001, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Caduceus 2001, Stritch School Of Medicine

Stritch School of Medicine Yearbooks

No abstract provided.