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Assessing Trends In Medical Students’ Perceptions Regarding Statistical Analysis, Ethan Noble, Valeriy Kozmenko, Paul Thompson

Scholarship Pathways Program

Assessing Trends in Medical Students’ Perceptions Regarding Data Analysis and Statistics Knowledge and Skills

Ethan Noble, MD | Mentors: Valeriy Kozmenko, MD, Paul Thompson, PhD

Introduction: The use of evidence-based medicine requires that physicians are able to properly analyze and interpret the results of new research. The development of new research and medical knowledge is swift, and a strong foundation in statistics and research is needed for physicians and medical students to keep up with new research. Curriculum in medical education often lacks in-depth coverage of the subject, and additional curriculum has been shown to enhance student confidence and ability …

Using Geospatial Analysis To Compare Metropolitan Greenspace And Adolescent Obesity, Rachel Schild, Denyelle Kenyon, Zachary Schild

Scholarship Pathways Program

Using Geospatial Analysis and Machine Learning to Compare Metropolitan Greenspace and Rates of Adolescents with Obesity

 Rachel Schild MD | DenYelle Kenyon PhD

 Introduction: Insufficient outdoor activity, influenced by limited access to exercise-friendly greenspaces, may contribute to increasing childhood obesity rates. However, rigorous evaluation of greenspace quality on a citywide scale is lacking. This study aims to characterize greenspace vegetation types and correlate them with adolescent obesity outcomes, identifying optimal characteristics for promoting health. This data could aid city planners in optimizing greenspace allocation and improving vegetation choices.

Methods: Satellite imagery and municipal data were used to map ten cities, …

Nudging Implementation Of Low Tidal Volume Ventilation: A Stepped Wedge, Cluster Randomized Trial, Meeta Prasad Kerlin, Michael O. Harhay, Fan Li, Dylan S. Small, Yingying Lu, Wei Wang, Barry D. Fuchs, Mark E. Mikkelsen, Teresa Tran, Aerielle Belk, Jasmine A. Silvestri, Tamar Klaiman, Stefania Scott, Elizabeth Levy, Michael W. Sjoding, Rachel Kohn, Karsten J. Roberts, Rinad S. Beidas, Scott D. Halpern

College of Health Professions Faculty Papers

BACKGROUND: "Nudges" embedded in the electronic health record (EHR) facilitate desired decisions while preserving autonomy and may provide a scalable strategy to overcome the common implementation barrier of lack of knowledge about a best practice. We sought to test whether EHR-based nudges targeting two intensive care unit (ICU) clinician groups would safely increase evidence-based use of low tidal volume ventilation.

METHODS: We performed a stepped-wedge, cluster randomized, hybrid type 3 effectiveness-implementation trial in 12 ICUs from February 2021 to May 2023 to test three nudges targeting clinicians responsible for order entry and respiratory therapists responsible for operationalizing orders and documentation. …

Staff Education To Improve Appointment Adherence In Outpatient Behavioral Health, Yvonne Joseph

Walden Dissertations and Doctoral Studies

No abstract provided.

Fall-Prevention Program For A Long-Term Care Organization, Roslyn Y. Heyward

Walden Dissertations and Doctoral Studies

No abstract provided.

Expertise First: Reflections On Informal Artificial Intelligence Mentoring In An Asynchronous Nursing Faculty Community, Anna Liza D. Villena Phd, Rn, Fnp-Bc

Journal of Online Mentoring

The integration of generative artificial intelligence (AI) into higher education has arrived faster than the support structures designed to help faculty navigate it. This article reflects on one faculty member’s experience providing informal AI integration mentoring to nursing colleagues at Walden University, a fully asynchronous online graduate nursing program, where clinician-educators with deep disciplinary expertise often struggled to recognize that expertise as an asset in their interactions with AI tools.

Drawing on Rogers’ (2003) diffusion of innovations theory, the article describes the mentoring approach that emerged from practice, the central insight that faculty are not failing to integrate AI because …

Comparative Behavioral Impacts Of Neuroactive Pharmaceuticals On Crayfish Locomotion, Grace Elizabeth Smith

Masters Theses

Pharmaceuticals are increasingly recognized as contaminants of concern in aquatic ecosystems, often entering waterways due to incomplete removal by wastewater treatment plants. Despite frequent detection, the effects of these compounds on non-target, neurochemically sensitive organisms such as crayfish remains underexplored. Gabapentin, an anticonvulsant that binds to presynaptic voltage-gated calcium channels and reduces excitatory neurotransmitter release, is one such emerging contaminant. Given crayfish’s ecological importance and sensitivity to neuroactive substances, exposure to gabapentin may disrupt key behaviors such as locomotion. To place gabapentin’s effects in context, we also examined escitalopram (Lexapro), a selective serotonin reuptake inhibitor that elevates synaptic 5-HT, and …

The Ethical Imperative Of Public Health Institutions To Protect The Reproductive Autonomy Of Vulnerable Populations, Kennethea Wilson

Electronic Theses and Dissertations

This dissertation establishes the ethical responsibility of public health institutions to safeguard reproductive autonomy, especially among vulnerable populations. While reproductive decision-making is traditionally framed within individual clinical encounters, this work contends that reproductive autonomy is fundamentally a matter of public health ethics. Socioecological determinants, including social, legal, environmental, and structural factors, often constrain individuals’ ability to make meaningful reproductive choices, leading to preventable harm.

Reproductive autonomy is defined as the capacity to make informed decisions about whether and when to conceive, as well as how to parent. The dissertation critiques the sufficiency of clinical ethics frameworks, such as informed consent …

Gut Microbiota Modulation Of Regulatory Dna Elements Revealed By Massively Parallel Functional Characterization, Chadmirah Zaratiana, Adheet Ganesh, Yang E Li, Et Al.

2020-Current year OA Pubs

Cis-regulatory elements (CREs) are central to dynamic gene regulation in hepatocytes, yet most functional annotations derive from in vitro models that poorly capture physiological regulation. We systematically profiled 109,386 human liver-derived CREs using massively parallel reporter assays in hepatocytes under matched in vitro and in vivo conditions. In vivo-active functional CREs (fCREs) were enriched for H3K27ac and chromatin accessibility and were regulated by diverse transcription factors in the human liver. We further demonstrate that gut microbiota-derived signals modulate fCRE activity and target gene expression in vivo, in part via the KEAP1/NFE2L2 antioxidant pathway. Specific microbial metabolites directly altered the activity …

Cellular And Molecular Basis Of Pfcoronin Function In Artemisinin Resistance In Plasmodium Falciparum, Imran Ullah, Eva S Istvan, Et Al.

2020-Current year OA Pubs

Artemisinin combination therapies are central to malaria control, but their efficacy is threatened by the emergence of resistant Plasmodium falciparum strains. While the role of Pfkelch13 mutations is well established, mutations in Pfcoronin have also been implicated in treatment failure, revealing layers of resistance complexity. Here, we define the cellular mechanism of Pfcoronin‑mediated artemisinin resistance. PfCoronin interacts with PfActin and localizes to the parasite plasma membrane, the digestive vacuole membrane, and small vesicles containing host cell material. Mutations in PfCoronin disrupt its localization and perturb PfActin homeostasis, altering the distribution of ring‑stage morphologies, including a reduced proportion of parasites adopting …

A Systematic Review And Meta-Analysis: Psychometric Properties Of Functional Tests In The Cancer Population, Mckenna Culter, Austin Schlater, Grace Molfenter, Mary Fisher

University of Dayton Doctor of Physical Therapy Annual Research Symposium

No abstract provided.

An After-School Adaptive Cycling Program For Children With Disabilities: A Pilot Study, Betsy Donahoe-Fillmore, Trisha A. Renner, Kate Burkart, Emma Feldman, Raegan Oehler, Kennedy Dedario, Britney Kozlowski, Terri Dinkelaker, Mary Fisher

University of Dayton Doctor of Physical Therapy Annual Research Symposium

No abstract provided.

A Comparison Of Drop Vertical Jump And Running Biomechanics Among Varying Experience Levels With Running, Jacob Hamme, Joaquin Barrios

University of Dayton Doctor of Physical Therapy Annual Research Symposium

No abstract provided.

The Ccu Disease Hunters: Putting Undergraduate Research To Work To Improve Community Health And Training The Next Generation Of Doctors, Paul E. Richardson

Journal of the South Carolina Academy of Science

No abstract provided.

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.

Development And Implementation Of A Tai Chi Group In A Community-Based Brain Injury Program, Haley D. White

Occupational Therapy Doctorate Capstone Posters

My capstone was completed at NeuroRestorative, a Neuro community-based setting that provides Occupational Therapy, Physical Therapy, and speech-language pathology. The purpose of the ALE and Capstone Project is to develop and implement a weekly tai chi group within a community-based brain injury setting that incorporates tiered modifications to address varying cognitive and physical abilities. The program is designed to promote improved overall functional participation while reducing periods of downtime and inactivity among participants. To support long-term sustainability and carryover, educational handouts and training materials will be provided to staff to facilitate ongoing implementation of the group intervention.

The goals of …

I Am God's Masterpiece: Ministry For Adults With Idd, Raegan M. Wilson

Occupational Therapy Doctorate Capstone Posters

This capstone project was completed in collaboration with Parkway Ministries in Corbin, Kentucky. My Applied Leadership Experience (ALE) took place in a community-based faith setting and focused on the ACOTE areas of Program Development, Education, and Advocacy. As part of a collaborative project to develop an inclusive Vacation Bible School (VBS) for adults with intellectual and developmental disabilities (IDD), my individual focus was supporting caregivers through education, resource development, and community engagement. A needs assessment and literature review identified caregiver burden, social isolation, limited educational resources, and reduced access to support services as common challenges for caregivers of adults with …

Improving Functional Electrical Stimulation Prescription For Persons With Multiple Sclerosis: A Case Series, Shahla Hosseini, Kimberly Bigelow, Nick Padgett, Robert Campbell, Lauren Boland, Skylar Forsberg, Brett Weaver, Kurt Jackson

University of Dayton Doctor of Physical Therapy Annual Research Symposium

No abstract provided.

The Effects Of Yoga On The Symptoms Of Perimenopause And Menopause: A Randomized Control Trial, Wendy Chorny, Betsy Donahoe-Fillmore, Brenlyn Rostad, Olivia Miller, Summer Rivas, Andrea Heitkamp, Cassidy Albers, Kennedi Gephart, Mary Fisher

University of Dayton Doctor of Physical Therapy Annual Research Symposium

No abstract provided.

A Tennis Ball Necklace As Simple Feedback To Effectively Reduce Impact Kinetics During Running, Kevin Sheehan, Matthew Minard, Andrew Clark, Jason Clingenpeel, Morgan Gigandet, Nicolas Love, Madison Scott, Joaquin Barrios

University of Dayton Doctor of Physical Therapy Annual Research Symposium

No abstract provided.

Determining The Concurrent And Predictive Validity Of The Repetitive Step Test In Individuals With Parkinson’S Disease, Harold Merriman, Kurt Jackson, Kyle Arrowood, Kaylee Virag

University of Dayton Doctor of Physical Therapy Annual Research Symposium

No abstract provided.

Split-Squat Lower Limb Biomechanics In Individuals With And Without Chronic Ankle Instability, Joaquin Barrios, Eva Carbone, Matt Cesario, Marshall Flynn, Danielle Updike

University of Dayton Doctor of Physical Therapy Annual Research Symposium

No abstract provided.

Soft Tissue Mobilization Versus Hold-Relax Stretching On Wrist Extensor Tendon Stiffness In Tennis Players, Brendan Burck, Adina Taylor, Cody Pohlman, Andrew Traven, Harold Merriman, Joseph Day

University of Dayton Doctor of Physical Therapy Annual Research Symposium

No abstract provided.

Genetic Analysis Of The X-Linked Adrenoleukodystrophy Gene Abcd1 In Drosophila Uncovers A Conserved Phenotype, Joshua Manor, Sharayu V Jangam, Hyung-Lok Chung, Pranjali Bhagwat, Jonathan C Andrews, Hillary Chester, Shu Kondo, Saurabh Srivastav, Juan Botas, Ann B Moser, Suzette M Huguenin, Michael F Wangler

Duncan NRI Faculty and Staff Publications

X-linked adrenoleukodystrophy (X-ALD) is a progressive neurodegenerative disorder caused by a loss-of-function (LOF) mutation in the ATP-binding cassette subfamily D member 1 (ABCD1) gene, leading to the accumulation of very long-chain fatty acids (VLCFAs). This disorder exhibits striking heterogeneity; some male patients develop an early childhood neuroinflammatory demyelination disorder, while other patients, including adult males and most affected female carriers, experience a chronic progressive myelopathy. Adrenocortical failure is observed in almost all male patients, with the age of onset varying, sometimes being the first diagnostic finding. The gene underlying this spectrum of disease encodes an ATP-binding cassette (ABC) transporter that …

Pharmacogenomic-Guided Prescribing And Polypharmacy Across Age Groups In Obsessive-Compulsive Disorder: A Retrospective Study, Sheldon R Garrison, Matthew W Boyer, Anthony W Zoghbi, Rachel A Schwartz, Nicolette Weisensel, Martin E Franklin, Madeline M Hartig, Maharaj Singh, Sreya Vadapalli

Faculty, Staff and Students Publications

Background: This study evaluated medication utilization in children, adolescents, and adults with obsessive-compulsive disorder (OCD), a chronic psychiatric condition characterized by intrusive thoughts and repetitive behaviors. Although first-line treatments include selective serotonin reuptake inhibitors (SSRIs) and cognitive behavioral therapy (CBT), the heterogeneous biological underpinnings contribute to suboptimal outcomes, with 40-60% of individuals not responding to SSRIs. This complex phenotype often leads to psychotropic polypharmacy, which may be mitigated by incorporating combinatorial pharmacogenomic (PGx) testing into protocol-based care to identify potential gene-drug interactions.

Methods: A retrospective review was conducted of individuals with OCD aged 8 to 65 years who received either …

Multi-Site Dms Probing Reveals Higher-Order Structure Of Rna-Protein Complexes In Living Cells, Irfana Saleem, Thomas Miller, Lucas Kearns, Anthony Hoang, Joshua Meehan, Ritwika Bose, David Mitchell, David H Price, Calla M Olson, Chase A Weidmann, Anthony M Mustoe

Faculty, Staff and Students Publications

Identifying tertiary structures and protein binding sites in RNA molecules remains a key challenge in RNA biology. We describe multi-site dimethyl sulfate (DMS)-mutational profiling (MaP) (msDMS-MaP), a strategy that enables simultaneous measurement of RNA secondary, tertiary, and quaternary structures via a single DMS chemical probing experiment. Optimized reverse transcription decodes typically invisible DMS N7-methylguanine (N7-G) modifications via a tautomer-induced mutational signature concurrent with N1 and N3 modifications. We show that N7-G reactivity reports on higher-order RNA structures, revealing key functional motifs such as pseudoknots and protein binding sites. Using msDMS-MaP, we find that E. coli ribosomal RNAs encode numerous independently …

Targeted Skin Cancer Education Improves Agricultural Workers' Safe Sun Practices And Knowledge In South Dakota: A Farm Show Survey, Leah Naasz, Kianna Thelen, Candace Zeigler

Scholarship Pathways Program

Targeted Skin Cancer Education Improves Agricultural Workers' Safe Sun Practices and Knowledge in South Dakota: A Farm Show Survey

Leah Naasz, MD | Candace Zeigler, MD

Background: Agricultural workers are at increased risk for skin cancer due to prolonged ultraviolet (UV) exposure, yet many underutilize sun protection. Brief, community-based educational interventions may improve knowledge and preventive behaviors.

Objective: To provide a targeted skin cancer educational session to increase awareness and promote sun protection behaviors among agricultural workers in South Dakota.

Methods: Twenty agricultural workers attending the Vermillion and Sioux Falls Farm Shows participated in a pre- and post-educational survey. Inclusion …

Program Development And Implementation Of A Sensory-Based Self Regulation Curriculum For Adults With Down Syndrome At Gigi’S Playhouse, Grace Blair

OTD Capstone Projects

This doctoral capstone project was completed through partnership with Gigi’s Playhouse Nashville, a non-profit organization offering free programming and services to individuals of all ages with Down syndrome and their families. The goal of this project was to develop and implement an educational curriculum for adult education programs focused on daily life skills, money management, physical health, self confidence, and a variety of other topics. A secondary focus of this project was to support sensory regulation in individuals with Down syndrome to promote overall health and participation. The results were physical and digital materials to be used for future adult …

Patient Reported Outcome Measure Use In Heart Transplant Care, Nichole Côté

Doctoral Projects

Despite growing evidence supporting Patient-Reported Outcome Measures (PROMs) in chronic disease management, no consistent application exists within the international heart transplant community. This Doctor of Nursing Practice project implemented the Kansas City Cardiomyopathy Questionnaire-12 (KCCQ-12) as a PROM within the a large volume heart transplant clinic, evaluating workflow feasibility, the association between Overall Summary Scores (OSS) and visit length, and clinician perceptions of PROM use. The KCCQ-12 was administered via a mobile health application with automated distribution. Workflow integration was assessed by calculating the percentage of scheduled visits with completed PROM documentation. Visit length was measured using electronic medical record …

Examining The Rural Workforce: Comparing Admissions Strategies And Training Pathways In U.S. Medical And Dental Education, Charolyn A. Harris

Honors Theses

Access to healthcare in rural and underserved communities remains a significant challenge in the United States, particularly in dental care, where workforce shortages are more pronounced. This study examines how medical and dental education programs develop rural healthcare providers, focusing on admissions strategies and training pathways. Using a structured scoping review and secondary data analysis, this research compares how each field incorporates known predictors of rural practice, such as rural background and training experiences, into workforce pipeline development. Findings indicate that while both medical and dental education recognize rural background as a strong predictor of rural practice, medical education more …