Digital Commons Network^™

Not A Waste: Wastewater Surveillance To Enhance Public Health, Anna Gitter, Jeremiah Oghuan, Anuja Rajendra Godbole, Carlos A. Chavarria, Carlos Monserrat, Tao Hu, Yun Wang, Anthony W. Maresso, Blake M. Hanson, Kristina D. Mena, Fuqing Wu

Pharmacy Faculty Articles and Research

Domestic wastewater, when collected and evaluated appropriately, can provide valuable health-related information for a community. As a relatively unbiased and non-invasive approach, wastewater surveillance may complement current practices towards mitigating risks and protecting population health. Spurred by the COVID-19 pandemic, wastewater programs are now widely implemented to monitor viral infection trends in sewersheds and inform public health decision-making. This review summarizes recent developments in wastewater-based epidemiology for detecting and monitoring communicable infectious diseases, dissemination of antimicrobial resistance, and illicit drug consumption. Wastewater surveillance, a quickly advancing Frontier in environmental science, is becoming a new tool to enhance public health, improve …

Moderation Effect Of Community Health On The Relationship Between Racial/Ethnic Residential Segregation And Hiv Viral Suppression In South Carolina: A County-Level Longitudinal Study From 2013 To 2018, Fanghui Shi, Jiajia Zhang Ph.D., Xueying Yang Ph.D., Xiaowen Sun, Zhenlong Li, Chengbo Zeng, Huan Ning, Sharon Weissman, Bankole Olatosi Ph.D., Xiaoming Li Ph.D.

Faculty Publications

Background: Viral suppression is the ultimate goal of the HIV treatment cascade and a primary endpoint of antiretroviral therapy. Empirical evidence found racial/ethnic disparities in viral suppression among people living with HIV (PWH), but the evidence of the relationship between racial/ethnic residential segregation and place-based viral suppression is scarce. Further exploring potential structural moderators in this relationship has substantial implications for healthcare policymaking and resource allocation. The current study aimed to investigate the spatial-temporal disparities in the HIV viral suppression rate across 46 counties in South Carolina from 2013 to 2018. We also examined the impact of racial/ethnic residential segregation …

Characteristics And Weight Loss Practices From A Cohort Of 20,000 Patients Using Direct-To-Consumer Telehealth: Observational Cross-Sectional Study, Deborah Bade Horn, Elizabeth Pash, Megan S Zhou, Lauren Broffman, Damian Bialonczyk, Tzvi Doron, Elaine Chiquette

Faculty, Staff and Student Publications

BACKGROUND: Despite the increasing prevalence of obesity, the use of pharmacotherapy treatment remains low. Telehealth platforms have the potential to facilitate access to pharmacotherapy interventions, but little is known about telehealth patients.

OBJECTIVE: This study describes a large patient population taking Plenity, an oral superabsorbent hydrogel (OSH) used in the treatment of excess weight or obesity (BMI 25-40 kg/m

METHODS: This was a cross-sectional assessment of a random sample of 20,000 telehealth patients who completed a structured, web-based visit and received at least one prescription of OSH. Patients were eligible to receive care via telehealth if they were adults, were …

Population Genomics Of Australian Indigenous Mesorhizobium Reveals Diverse Nonsymbiotic Genospecies Capable Of Nitrogen-Fixing Symbioses Following Horizontal Gene Transfer, Elena Colombi, Yvette Hill, Rose Lines, John T. Sullivan, Maclean G. Kohlmeier, Claus T. Christophersen, Clive W. Ronson, Jason J. Terpolilli, Joshua P. Ramsay

Research outputs 2022 to 2026

Mesorhizobia are soil bacteria that establish nitrogen-fixing symbioses with various legumes. Novel symbiotic mesorhizobia frequently evolve following horizontal transfer of symbiosis-gene-carrying integrative and conjugative elements (ICESyms) to indigenous mesorhizobia in soils. Evolved symbionts exhibit a wide range in symbiotic effectiveness, with some fixing nitrogen poorly or not at all. Little is known about the genetic diversity and symbiotic potential of indigenous soil mesorhizobia prior to ICESym acquisition. Here we sequenced genomes of 144 Mesorhizobium spp. strains cultured directly from cultivated and uncultivated Australian soils. Of these, 126 lacked symbiosis genes. The only isolated symbiotic strains were either exotic strains used …

The Future Of Health Care Work And The Place Of Migrant Workers Within It: Internationally Educated Nurses In Ontario Canada During The Covid-19 Pandemic, Margaret Walton-Roberts

Global Nurse Migration Pathways: A Comparative Project

The COVID-19 pandemic highlighted the importance of immigrant health workers in OECD nations, and intensified debates about the current and future supply and distribution of such workers, particularly nurses. This review paper considers internationally educated nurses in the case of Ontario, Canada, and the policy responses developed during the pandemic to address the increased utilization of immigrant health workers. To further consider the evolving place of migrant workers within health, the broader issue of the future of health care work is examined to imagine what a sustainable and resilient health workforce agenda that integrates internationally educated nurses might look like.

Sexually Transmitted Infections And Social Determinants Of Health: Emerging Opportunities In The Medicaid Program, Naomi Seiler, Katie Horton, Paige Organick-Lee, Mekhi Washington, Taylor Turner, Lily Ryan

Health Policy and Management Informal Communications

No abstract provided.

2023 Apothecary, Southwestern Oklahoma State University

Apothecary

It is with great honor that we present the 2023 Apothecary issue. This year's Apothecary was made possible by generous financial contributions from many stores, businesses, and Southwestern College of Pharmacy alumni. We greatly appreciate and thank you for your continued support.

The Apothecary staff would like to thank Dr. Les Ramos and Adina Foust. This process would not have been possible without their continuous support, patience, and behind-the-scenes efforts. We also want to thank the SWOSU Design Studio for their hard work in creating this year's fantastic cover and dividers. You always help bring our ideas to life and …

Telehealth Benefits In Rural Areas: Occupational Therapy, Grant E. Tolkkinen, Grace K. Torgerson, Kaitlyn J. Wanner

Critically Appraised Topics

This paper focuses on the efficacy of occupational-based interventions administered via telehealth within a rural-dwelling adult (18 years and older) population with mental health conditions. The main factors to consider in this scenario are the mental health services in rural areas, the features of the rural population, and the role of occupational therapy (OT) and telehealth in rural mental health. The Occupational Therapy Practice Framework defined health management as “activities related to developing, managing, and maintaining health and wellness routines, including self-management, with the goal of improving or maintaining health to support participation and other occupation” (AOTA, 2020, p.32).

Tularemia Seroprevalence In Humans In The Region Of The Hittite-Arzawa War (Inner Aegean Region), Where The First Biological Weapon Was Used 3300 Years Ago, İsmai̇l Davarci, Canan Eryildiz, Duygu Perçi̇n Renders, Ufuk Berberoğlu, Şaban Gürcan

Turkish Journal of Medical Sciences

Background/aim: According to Egyptian records, tularemia emerged in the Canaan region, where it was first identified and spread to Anatolia over the Euphrates. It was used as an active biological weapon for the first time in the Hittite-Arzawa War in 1320-1318 BC. This study aimed to investigate the seroprevalence of tularemia in the Inner Aegean Region, which is thought to be the region where this war was fought 3300 years ago. Materials and methods: Tularemia seropositivity in humans was investigated in 27 villages/neighborhoods in 3 districts in each of Manisa, Kütahya, and Uşak provinces. Before the study, the participants were …

Covid-19 Modeling Based On Real Geographic And Population Data, Emi̇r Baysazan, Ahmet Ni̇hat Berker, Hasan Mandal, Hakan Kaygusuz

Turkish Journal of Medical Sciences

Background/aim: Intercity travel is one of the most important parameters for combating a pandemic. The ongoing COVID-19 pandemic has resulted in different computational studies involving intercity connections. In this study, the effects of intercity connections during an epidemic such as COVID-19 are evaluated using a new network model. Materials and methods: This model considers the actual geographic neighborhood and population density data. This new model is applied to actual Turkish data by means of provincial connections and populations. A Monte Carlo algorithm with a hybrid lattice model is applied to a lattice with 8802 data points. Results: Around Monte Carlo …

Impact Of State-Led Surveillance Programs On Neonatal Abstinence Syndrome, Patricia Lewis

Theses, Dissertations and Capstones

Introduction: Neonatal Abstinence Syndrome (NAS) has been costly for the healthcare system, for every 24 minutes a baby was diagnosed in 2020. Uniform programs to diagnosis, track and prevent NAS have not been implemented previously. The NCBDDD worked with 6 states to implement a uniform surveillance program. By tracking the NAS incidence rate, the Apgar scores of infants with NAS, the length of stay for those infants, the cost of care for those infants and the percentage of mothers of infants with NAS were participating in Medication Assisted Treatment the effectiveness of the surveillance programs may be assessed.

Methodology: This …

Perceptions Of Occupational Therapists Working In Established Pace Programs, Jessica L. Daugherty-Peters

Occupational Therapy Doctorate Capstone Projects

Background: The Program of All Inclusive Care for the Elderly (PACE) provides medical and social services to older adults who meet nursing home level of care but wish to remain in their own homes. Although PACE has been in existence for decades, this program is new to the state of Kentucky.

Purpose: The problem this Capstone project will address is the need for further research related to occupational therapy’s roles and experiences in PACE programs. This capstone will explore the perceptions of occupational therapists and occupational therapy assistants working in established PACE programs.

Methods: This study followed a Qualitative Descriptive …

Progression Magazine, 2022-2023, Coastal Carolina University

Progression Magazine

Magazine of the Gupta College of Science at Coastal Carolina University.

Individual‑Level Patterns Of Resource Selection Do Not Predict Hotspots Of Contact, Anni Yang, Raoul Boughton, Ryan S. Miller, Nathan P. Snow, Kurt C. Vercauteren, Kim C. Pepin, George Wittemyer

United States Department of Agriculture Wildlife Services: Staff Publications

Contact among animals is crucial for various ecological processes, including social behaviors, disease transmission, and predator–prey interactions. However, the distribution of contact events across time and space is heterogeneous, influenced by environmental factors and biological purposes. Previous studies have assumed that areas with abundant resources and preferred habitats attract more individuals and, therefore, lead to more contact. To examine the accuracy of this assumption, we used a use-available framework to compare landscape factors influencing the location of contacts between wild pigs (Sus scrofa) in two study areas in Florida and Texas (USA) from those influencing non-contact space use. …

Evaluation Of The Effect Of Hydrated Lime On The Scavenging Of Feral Swine (Sus Scrofa) Carcasses And Implications For Managing Carcass-Based Transmission Of African Swine Fever Virus, Courtney F. Bowden, James Grinolds, Gregory Franckowiak, Loma Mccallister, Joe M. Halseth, Matthew Cleland, Travis Guerrant, Michael J. Bodenchuk, Robert Miknis, Michael C. Marlow, Vienna R. Brown

United States Department of Agriculture Wildlife Services: Staff Publications

African swine fever (ASF) is a devastating hemorrhagic disease marked by extensive morbidity and mortality in infected swine. The recent global movement of African swine fever virus (ASFV) in domestic and wild swine (Sus scrofa) populations has initiated preparedness and response planning activities within many ASF-free countries. Within the US, feral swine are of utmost concern because they are susceptible to infection, are wide-spread, and are known to interact with domestic swine populations. African swine fever virus is particularly hardy and can remain viable in contaminated carcasses for weeks to months; therefore, carcass-based transmission plays an important role in the …

Role Of Social Structure In Establishment Of An Invasive Large Mammal After Translocation, Lindsay M. Clontz, Anni Yang, Sarah M. Chinn, Kim M. Pepin, Kurt C. Vercauterten, George Wittemyer, Ryan S. Miller, James C. Beasley

United States Department of Agriculture Wildlife Services: Staff Publications

Background

Data on the movement behavior of translocated wild pigs is needed to develop appropriate response strategies for containing and eliminating new source populations following translocation events. We conducted experimental trials to compare the home range establishment and space-use metrics, including the number of days and distance traveled before becoming range residents, for wild pigs translocated with their social group and individually.

Results

We found wild pigs translocated with their social group made less extensive movements away from the release location and established a stable home range ~5 days faster than those translocated individually. We also examined how habitat quality …

Sisyphean Frustrations: The Impetus For Improving Harm Reduction Strategies In Minneapolis, Mn, Jordan Baker

Theses and Graduate Projects

Background: The last decade has seen an alarming rise in deaths attributed to opioid use. Considering the ever-increasing mortality rate contributable to opiate use disorder, it is important to identify and utilize more efficacious public health interventions.

Purpose: The focus of this paper is identifying the current harm reduction strategies being implemented in Minneapolis MN, the history of harm reduction in the US, and opportunities to improve existing systems to better engage current conditions.

Methods: The primary research method for this community assessment was volunteer work with Southside Harm Reduction in Minneapolis, MN. Through community clean-ups the researcher was able …

Factors Impacting Adherence To Antidiabetic Medications And Health Outcomes In Diabetes Mellitus Patients In Medicare Populations, Kelli Hoang, Kelly Simpson, Danny Wallenslager

Providence Pharmacy PGY1 Program at Providence Portland and Providence St. Vincent Medical Centers 2023

No abstract provided.

Sociodemographic Predictors Of Veterans’ Health-Related Quality Of Life, Tamala Jones Choice

Walden Dissertations and Doctoral Studies

Health-related quality of life (HRQoL) is a theoretical concept that intertwines physical, mental, emotional, and social functioning, with a focus on the impact that health status has on quality of life. Although sociodemographic factors are associated with lower HRQoL, how these factors influence HRQoL in military veterans is less understood. The study’s purpose was to examine the relationships between sociodemographic characteristics (gender, military pay grade, military branch, and geographic location) and perceived HRQoL measured by the SF-8 survey among veterans living in a metropolitan community in the Mid-Atlantic region of the United States. A cross-sectional recruitment study design yielded 90 …

Barriers To Sleep In Us Army Service Members: A Scoping Review, Sally Paul

Occupational Therapy Doctorate Capstone Projects

Background: Insufficient sleep contributes to human health and performance deficits with Active Duty US Army soldiers being at highest risk for poor sleep and subsequent sleep disorders. Research in this area continues to grow and has focused on pathology and intervention, often related to deployment, yet it is vital to understand the barriers to sufficient sleep in healthy soldiers (the majority) in the garrison context, where they will spend most of their time. Purpose: Explore the current state of literature regarding barriers to sufficient sleep in healthy US Army active duty service members in the garrison setting. Theoretical Framework. Biopsychosocial …

Keynote Address And Meeting Program, Academy Editors

Journal of the Arkansas Academy of Science

No abstract provided.

An Analytic And Systemic View Of The Digital Transformation Of Healthcare, Xuejuan J. Zhang

Full-Text Theses & Dissertations

Industry 4.0 represents a digital revolution that is driven by technologies that blur the lines between the physical and digital worlds. Industry 4.0, the latest industrial revolution, is poised to have a profound impact on all aspects of society. In order to understand how the healthcare industry is being transformed by the convergence of the physical and digital realms, a systems perspective is taken in this study. Two research questions are addressed regarding the opportunities and interventions that can be provided by both analytical and systems conceptions of digital transformation. I use a systemic literature review approach to address the …

Intersectoral Responses To Climate Change And Waterborne Diseases In The Caribbean Region: Current Actions And Pathways Forward Using The One Health Framework, Sydney A. Steel

Public Health Theses

The Caribbean exists on the frontlines of climate change, and many climate-related threats are already felt throughout the region and projected to worsen in the coming decades. A critical climate-related threat is that of waterborne diseases, as extreme weather events, sea level rise, and temperature increases are shown to contribute to potable water inaccessibility and a more favorable environment for pathogen proliferation and transmission. The complexity of this challenge calls for increased regional and inter-sectoral collaboration in both preparedness and response efforts. Countries and territories across the Caribbean are currently displaying variable yet marked interest in One Health, yet there …

The Influence Of Internalized Heterosexism On Life Satisfaction: Comparing Sexual Minority Women In Belgium And Turkey, Esra Ummak, Ezgi Toplu-Demirtaş, Amber L. Pope, Jeffry Moe

Counseling & Human Services Faculty Publications

To date, the majority of research studying lesbian, gay, bisexual, transgender, and queer (LGBTQ) health has been conducted in Westernized, predominantly individualistic countries. Building on minority stress theory and models of LGBTQ health, we explored how sexual orientation and nationality moderated the association between internalized heterosexism and life satisfaction for lesbian and bisexual (LB) women living in two countries (Turkey and Belgium) with contrasting social contexts. The results of two-way MANOVA, in a sample of 339 Turkish and 220 Belgian LB women, revealed main effects but no interaction effects. LB women in Belgium reported less internalized heterosexism and more life …

Self-Reported Tea Consumption And Age-Related Macular Degeneration In U.S. Adults, Lindsey Halasz Shaffer

Graduate Research Theses & Dissertations

Background: Age-related Macular degeneration (AMD) is a multifaceted disease of aging that is currently one of the leading causes of blindness in the US. As aging populations continue to turn to alternatives to prevent age-related diseases, the use of tea antioxidants has been suggested as potential protectors against cellular degradation and oxidation within the retina. To date, no epidemiologic or cross-sectional studies have been conducted regarding the correlation between tea intake and AMD, as it has for other diseases of with antioxidant mitigation potential, such as cancer. Objective: The purpose of this cross-sectional study was to examine the correlation between …

Epigenetics And Social Inequalities In Asthma And Allergy, Elizabeth S. Clausing, Cassidy J. Tomlinson, Amy L. Non

School of Global Integrative Studies: Faculty Publications

Respiratory illnesses, such as asthma and allergy disorders, are disproportionately more common among minority racial/ethnic groups and those of low socioeconomic status. In the United States, asthma prevalence and severity are highest among Puerto Ricans (19.2%), American Indians/Alaska Natives (13%), and Black Americans (12.7%) and higher in families living below the poverty threshold than among those living above it (11% vs 8%–9%).¹ Many studies of asthma/allergy inequalities assume that genetic differences underlie racial/ethnic differences in these disorders, pointing to genetic ancestry differences between races, but most genetic variants fail to explain racial/ethnic differences and are usually studied only in …

Modeling Spatial Access To Healthcare, Yaxiong Shao

Graduate Research Theses & Dissertations

Health disparity has been a persistent concern in the United States, and the COVID-19 pandemic has brought more attention to this ongoing challenge. Improving access to healthcare is a crucial step toward achieving health equity and starts with accurately measuring and portraying the existing landscape of access to healthcare. Even though numerous spatial accessibility models have been proposed to measure the spatial accessibility to healthcare, many gaps still exist. The main purpose of this dissertation is to develop novel models and leverage recently available datasets for a more accurate portrayal of true spatial accessibility. Three models were developed to address …

Exploring Supports And Barriers To Inclusion In Occupational Therapy Education, Arielle Ramirez, Anne F. Kiraly-Alvarez

Journal of Occupational Therapy Education

The recent innumerable social and racial injustices and healthcare disparities experienced globally have catapulted diversity and inclusion discussions to the forefront. The purpose of this study was to identify the supports and barriers to inclusion in occupational therapy (OT) education from the experiences of OT students from historically marginalized groups and the perspectives of OT faculty/staff. The authors used a convergent mixed methods design for the study, which consisted of an online survey and semi-structured interviews. 131 students and 35 faculty/staff completed the survey, while 20 students and 11 faculty completed interviews. Five themes emerged from the data: 1) Barriers …

Evaluating Spatial Relationships Between Environmental Factors And Contextual Sociodemographic Burden And Associations With Respiratory Morbidity Among Young Children: An Indicator-Based Approach, Neil Anthony Muscatiello

Legacy Theses & Dissertations (2009 - 2024)

The body of public health literature related to air pollution epidemiology is extensive. Similarly, the body of literature related to social epidemiology has also expanded greatly in recent years. While studies in these sub-disciplines of epidemiology sometimes seek to control for variables more commonly studied in one or the other, fewer studies report on their combined effects. Studies which do attempt to summarize how the combined air pollution burden and contextual sociodemographic burden differentially effect health outcomes beyond their individual effects could be beneficial in understanding links between the environment and certain health outcomes such as childhood asthma. The proposed …

Understanding And Targeting The Tph1-Serotonin-Htr3a Axis In Small Cell Lung Cancer, Yanning Hao

Theses and Dissertations--Toxicology and Cancer Biology

Small cell lung cancer (SCLC), which accounts for 10-15% of all lung cancer, is the most malignant type that tends to grow fast and spread in its early stages. The 5-year survival rate remains low at 6% overall. Thus, new therapeutic methods and pharmacological targets for SCLC patients are urgently needed. We present novel data indicating that the synthesis of serotonin is upregulated in SCLC compared to normal bronchial epithelial cells and non-small cell lung cancer. Serotonin signaling plays a critical role in various physiological and pathological processes. However, its contribution to SCLC development has not been well understood. The …