Digital Commons Network^™

Vegetarian Dietary Patterns: Mortality, Colorectal Cancer, And Food Consumption, Michael John Orlich

Loma Linda University Electronic Theses, Dissertations & Projects

Objective Vegetarian dietary patterns represent longstanding, real-world diets consumed by a minority of persons. Studies of important health outcomes of such diets, particularly for all-cause mortality and colorectal cancer risk, have yielded inconsistent results. We sought to examine these outcomes (mortality and colorectal cancer incidence) in a large North-American cohort. We also sought to further characterize potentially important differences in the food consumption patterns of these diets. Design Baseline diet was measured by a quantitative food frequency questionnaire among more than 96,000 Seventh-day Adventists in the US and Canada, enrolled from 2002-2007. Dietary patterns were defined, based on the reported …

How To Approach Research : A Guide For Child Life Specialists, Emily L. Springer

Graduate Student Independent Studies

This how-to guide aims to increase the understanding of research and provide child life specialists and students a concise and easy tool to access information about how they incorporate research into their work.

Ultraviolet Radiation, Aging And The Skin: Prevention Of Damage By Topical Camp Manipulation, Alexandra Amaro-Ortiz, Betty Yan, John A. D’Orazio

Markey Cancer Center Faculty Publications

Being the largest and most visible organ of the body and heavily influenced by environmental factors, skin is ideal to study the long-term effects of aging. Throughout our lifetime, we accumulate damage generated by UV radiation. UV causes inflammation, immune changes, physical changes, impaired wound healing and DNA damage that promotes cellular senescence and carcinogenesis. Melanoma is the deadliest form of skin cancer and among the malignancies of highest increasing incidence over the last several decades. Melanoma incidence is directly related to age, with highest rates in individuals over the age of 55 years, making it a clear age-related disease. …

Nutritional Counseling At Jeffhope, Cara Siegel, Msii, Anita Modi, Msiii, Amy Tressan, Msi

CwiC-PH

INTRODUCTION

Obesity is a major national public health concern and is strongly associated with increased morbidity and mortality.¹ Specifically, obesity is correlated to increased frequency in coronary artery disease², type two diabetes³, some cancers⁴, and other serious health conditions⁵. An epidemiological study of 21 developed countries found that increased waist size, weight, and BMI were all associated with low income.⁷ Importantly, obesity has a high prevalence among the homeless population, one study finding 42.8% of homeless women obese.¹⁷ It has been reported that 39% of sheltered homeless Americans are …

Quality Of Primary Care From The Patient Perspective In Saudi Arabia : A Multi-Level Study., Khalid Awad Alahmary

Electronic Theses and Dissertations

Objectives: To assess primary care performance for measures of patients’ experience in Community-based Primary Care (CPC) and Employer-based Primary Care (EPC) systems in Saudi Arabia, to examine variations in performance across the two systems, and to explore factors at both the individual-level and the organizational-level that explain variations in primary care performance. Design and Methods: This is an observational and cross-sectional study, using comparative design and survey research methods. The newly revised and re-translated Arabic version of the Primary Care Assessment Survey (PCAS) was used to measure patients’ experience of primary care. PCAS operationalizes the IOM definition of primary care, …

Spatiotemporal Distribution Of Genus Culex (Diptera: Culicidae) In Usf Ecopreserve, Hillsborough County, Florida, Emily Schwartz

USF Tampa Graduate Theses and Dissertations

Within the state of Florida, there are three arboviruses of public health importance that can cause neuroinvasive disease in humans: West Nile Virus, Saint Louis Encephalitis Virus, and Eastern Equine Encephalitis Virus. Mosquitoes (Diptera: Culicidae) within the genus Culex are known and suspected vectors of these diseases. The vectors of these diseases can be present in urban wetland habitats that allow for exposure to residential communities. Vector ecology must be investigated in order to understand the dynamics of disease transmission. In Hillsborough County, Florida the spatial and temporal distribution of these vectors are not well established. An ecological study was …

Global Rise In Human Infectious Disease Outbreaks, Katherine F. Smith, Michael Goldberg, Samantha R. Rosenthal, Lynn Carlson, Jane Chen, Cici Chen, Sohini Ramachandran

Health & Wellness Department Faculty Publications and Research

No abstract provided.

Interaction Between Climatic, Environmental, And Demographic Factors On Cholera Outbreaks In Kenya, James D. Stoltzfus, Jane Y. Carter, Muge Akpinar-Elci, Martin Matu, Victoria Kimotho, Mark J. Giganti, Daniel Langat, Omur C. Elsi

Community & Environmental Health Faculty Publications

Background:

Cholera remains an important public health concern in developing countries including Kenya where 11,769 cases and 274 deaths were reported in 2009 according to the World Health Organization (WHO). This ecological study investigates the impact of various climatic, environmental, and demographic variables on the spatial distribution of cholera cases in Kenya.

Methods:

District-level data was gathered from Kenya’s Division of Disease Surveillance and Response, the Meteorological Department, and the National Bureau of Statistics. The data included the entire population of Kenya from 1999 to 2009.

Results:

Multivariate analyses showed that districts had an increased risk of cholera outbreaks when …

Exposure To Multiple Parasites Is Associated With The Prevalence Of Active Convulsive Epilepsy In Sub-Saharan Africa, Gathoni Kamuyu, Christian Bottomley, James Mageto, Brett Lowe, Patricia Wilkins, John C. Noh, Thomas B. Nutman, Anthony Ngugi, Rachael Odhiambo, Ryan Wagner, Angelina Kakooza-Mwesige, Seth Owusu-Agyei, Kenneth Ae-Ngibise, Honorati Masanja, Faith Osier, Peter Odermatt, Charles Newton

Family Medicine, East Africa

Background: Epilepsy is common in developing countries, and it is often associated with parasitic infections. We investigated the relationship between exposure to parasitic infections, particularly multiple infections and active convulsive epilepsy (ACE), in five sites across sub-Saharan Africa.

Methods and Findings: A case-control design that matched on age and location was used. Blood samples were collected from 986 prevalent cases and 1,313 age-matched community controls and tested for presence of antibodies to Onchocerca volvulus, Toxocara canis, Toxoplasma gondii, Plasmodium falciparum, Taenia solium and HIV. Exposure (seropositivity) to Onchocerca volvulus (OR = 1.98; 95%CI: 1.52-2.58, p

Conclusion: This study investigates how …

Atrazine In Maternal Drinking Water Supply Below The Federal Maximum Contaminant Level And Risk Of Preterm Birth, Small For Gestational Age, Cryptorchidism And Hypospadias, Daniel Rice

Legacy Theses & Dissertations (2009 - 2024)

The prevalence of preterm birth, small for gestational age (SGA), and hypospadias has been increasing for several decades in the U.S resulting in significant morbidity and mortality and direct costs to society. Drinking water provides a mechanism for prolonged chronic exposure to environmental contaminants but is one of the least assessed environmental exposures in pregnancy and birth outcomes. To test the hypothesis that maternal exposure to atrazine through drinking water during pregnancy, or one or more trimesters of gestation, is associated with an increased risk of preterm birth, small for gestational age, cryptorchidism and hypospadias a retrospective cohort study was …

Transgenerational Transmission Of Trauma In Second Generation Latino Children And Adolescents, Ricardo Phipps

Electronic Theses and Dissertations

This study explored the impact that immigration-related trauma has upon families, particularly second-generation immigrant children in the Latino-American community in the United States, and the possibility that second-generation immigrant Latinos are vulnerable to transgenerational trauma. Transgenerational trauma involves the exhibition of posttraumatic stress disorder (PTSD) symptoms in subsequent generations in families with histories of trauma exposure. Multiple linear regression was conducted to explore the existence of a correlation between PTSD and depression in second-generation Latino immigrant children and adolescents with a myriad of potentially predicting factors. Enhanced understanding of how trauma can affect the children of traumatized immigrants will add …

Hepatitis B, C Virus And Hiv Co-Infection Among Reported Female Cases In South Carolina, 2004 - 2011: An Epidemiological Analysis Of Pregnancy Outcomes, Afiba Manza-Azele Agovi

Theses and Dissertations

HIV, hepatitis B and C virus (HBV, HCV) are three of the most common blood-borne infections and they continue to be a major public health problem in the United States (US) and globally. It is not well understood if maternal infection with either HBV or HCV has an adverse impact on pregnancy outcomes as findings from previous studies have provided some mixed results. The overall goal of this study was to assess the risk of preterm birth, low birth weight (LBW), small for gestational age (SGA) and admission into neonatal intensive care unit (NICU) for babies born to HBV- and …

Antibiotic Usage In Relation To Resistant Bacterial Infections And Liver And Kidney Cancer Outcomes In South Carolina, Prea Thathiah

Theses and Dissertations

Antibiotics are one of the most beneficial discoveries in medicine and public health. However, the use, overuse, and misuse of these drugs have led to increases in antibiotic resistant bacterial infections (ARI). Furthermore, previous epidemiological studies have linked antibiotic use to breast cancer, but these studies have not included effects on metabolic organs, such as the liver and kidneys. This dissertation investigates the role of antibiotic use in infections and liver and kidney cancers in the state of South Carolina. Using ecological study methods and Poisson regression to determine relative risk ratios, it was found that antibiotic use is a …

Distribution Of Wildlife Rabies In Central Appalachia And Analysis Of Factors Influencing Human Exposure, Sara J. Reilly

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Abstract Background: The rabies virus is a Lyssavirus of the family Rhabdoviridae which affects all mammals and causes progressive encephalomyelitis that is fatal in nearly one hundred percent of untreated cases. In the United States, wildlife act as the primary reservoir for rabies and prevention, surveillance, and control costs remain high. The purpose of this study is to understand the current distribution of wildlife rabies in Central Appalachia, as well as identify any demographic or geographic factors which may affect the risk of human exposure at the county level. Methods: A spatial statistical analysis using StatScan was performed to identify …

Exposure To Endocrine Disrupting Chemicals And Male Reproductive Health, Hueiwang Anna Jeng

Community & Environmental Health Faculty Publications

Endocrine disrupting chemicals (EDCs) can interfere with normal hormonal balance and may exert adverse consequences on humans. The male reproductive system may be susceptible to the effects of such environmental toxicants. This review discusses the recent progress in scientific data mainly from epidemiology studies on the associations between EDCs and male reproductive health and our understanding of possible mechanisms associated with the effects of EDCs on male reproductive health. Finally, the review provides recommendations on future research to enhance our understanding of EDCs and male reproductive health. The review highlights the need for (1) well-defined longitudinal epidemiology studies, with appropriately …

Comparative Study Of Helminth Parasites Of The Many-Ribbed Salamander, Eurycea Multiplicata And Oklahoma Salamander, Eurycea Tynerensis (Caudata: Plethodontidae), From Arkansas And Oklahoma, A, C. T. Mcallister, M. B. Connior, C. R. Bursey, H. W. Robison

Journal of the Arkansas Academy of Science

Ninety many-ribbed salamanders, Eurycea multiplicata and 135 Oklahoma salamanders, Eurycea tynerensis were collected between April 2010 and April 2014 from 14 counties of Arkansas and McCurtain County, Oklahoma (E. multiplicata only) and examined for helminth parasites. Twelve (13%) E. multiplicata were infected, including two (2%) each with Brachycoelium salamandrae, Bothriocephalus rarus, Batracholandros magnavulvaris, Cosmocercoides variabilis, and Omeia papillocauda, and one (1%) each with an oligacanthorhynchid cystacanth and Fessisentis vancleavei. Forty-one (30%) of the E. tynerensis were infected, including seven (5%) with Gorgoderina tenua, two (1%) each with Phyllodistomum solidum and cyclophyllidean tapeworm cysticerci, one (0.7%) with Cylindrotaenia americana, six (3%) …

Finding Them Before They Find Us: Informatics, Parasites, And Environments In Accelerating Climate Change, Daniel R. Brooks, Eric P. Hoberg, Walter A. Boeger, Scott Lyell Gardner, Kurt E. Galbreath, David Herczeg, Hugo H. Mejía-Madrid, S. Elizabeth Rácz, Altangerel Tsogtsaikhan Dursahinhan

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Parasites are agents of disease in humans, livestock, crops, and wildlife and are powerful representations of the ecological and historical context of the diseases they cause. Recognizing a nexus of professional opportunities and global public need, we gathered at the Cedar Point Biological Station of the University of Nebraska in September 2012 to formulate a cooperative and broad platform for providing essential information about the evolution, ecology, and epidemiology of parasites across host groups, parasite groups, geographical regions, and ecosystem types. A general protocol, documentation–assessment–monitoring–action (DAMA), suggests an integrated proposal to build a proactive capacity to understand, anticipate, and respond …

Relationship Between Diabetes And Indoor Air Pollution: An Exploratory Analysis, Sandeep Mishra

All ETDs from UAB

India has the second highest number of people with diabetes. The high prevalence of diabetes in India cannot be explained on the basis of established risk factors like obesity. The role of air pollution in diabetes has recently received attention. Studies have indicated the possibility that air pollution generated by traffic might be associated with increased risk of diabetes. Published literature lacks studies that assess the relationship between indoor air pollution and diabetes, although indoor air pollution can lead to higher levels of pollutants in house compared to traffic pollution. The current study determined the relationship between indoor air pollution …

The Burden Of Avian Influenza Viruses In Community Ponds In California, Zin Htway

Walden Dissertations and Doctoral Studies

Emerging influenza viruses continue to challenge public health. The problem is public health science professionals have been battling emerging human influenza diseases with tactile and reactionary methods because there is a lack of knowledge and data at the human-animal interface. This research was a baseline study of the proportion of influenza A virus (IAV) in urban and rural communities in California. The population was artificial recirculating water ponds in the geographic locations of rural and urban Californian communities. Surface water samples [N = 182] were collected from artificial recirculating ponds in California. Positivity for IAV was verified by real time …

North American Lyme Borreliae: New Distributions And An Insight Into Borrelia Bissettii Infection, Immune Response And Transmission In A Murine Model, Brian Francis Leydet Jr

LSU Doctoral Dissertations

Lyme borreliosis is an emergent threat to human health. It is estimated that 300,000 cases of Lyme disease are diagnosed annually in the United States. In recent years, non-traditional areas are starting to report more and more cases. While much research has gone into the tick and bacteria responsible for the disease, frequently new Borrelia species are being described and implicated in human illness. These species often go unstudied, and their threat to human health is not known. In the hopes of closing knowledge gaps on Lyme borreliosis in the US, we surveyed a non-endemic state, Louisiana, for Lyme Borrelia …

The Efficacy And Safety Of The Human Papillomavirus Vaccine, Gail Tessler

The Science Journal of the Lander College of Arts and Sciences

The HPV virus is said to be the cause of many infections, warts, and cancers. In addition to the fact that the treatment for HPV is not always successful, not every individual knows that s/he is infected and is very likely to infect his or her partner, too. This is one factor that explains why 14 million people each year in America alone contract HPV and makes cervical cancer so threatening to many people worldwide. In light of this and the known dangers of cervical, anal, vaginal and penile cancers, the HPV vaccine was created to prevent an infection of …

Evidence For Finely-Regulated Asynchronous Growth Of Toxoplasma Gondii Cysts Based On Data-Driven Model Selection, Adam M. Sullivan, Xiaopeng Zhao, Yasuhiro Suzuki, Eri Ochiai, Stephen Crutcher, Michael A. Gilchrist

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Toxoplasma gondii establishes a chronic infection by forming cysts preferentially in the brain. This chronic infection is one of the most common parasitic infections in humans and can be reactivated to develop life-threatening toxoplasmic encephalitis in immunocompromised patients. Host-pathogen interactions during the chronic infection include growth of the cysts and their removal by both natural rupture and elimination by the immune system. Analyzing these interactions is important for understanding the pathogenesis of this common infection. We developed a differential equation framework of cyst growth and employed Akaike Information Criteria (AIC) to determine the growth and removal functions that best describe …

A Population-Based Case–Control Study Of Urinary Arsenic Species And Squamous Cell Carcinoma In New Hampshire, Usa, Diane Gilbert-Diamond, Zhigang Li, Ann E. Perry, Steven K. Spencer, A Jay Gandolfi, Margaret R. Karagas

Dartmouth Scholarship

Background: Chronic high arsenic exposure is associated with squamous cell carcinoma (SCC) of the skin, and inorganic arsenic (iAs) metabolites may play an important role in this association. However, little is known about the carcinogenicity of arsenic at levels commonly observed in the United States.

Objective: We estimated associations between total urinary arsenic and arsenic species and SCC in a U.S. population.

Methods: We conducted a population-based case–control SCC study (470 cases, 447 controls) in a U.S. region with moderate arsenic exposure through private well water and diet. We measured urinary iAs, monomethylarsonic acid (MMA), and dimethylarsinic acid (DMA), and …

Explanations For An Increased Cesarean Birth Rate In Guayaquil, Ecuador, Melissa Kemp, Dr. Sheri Palmer

Journal of Undergraduate Research

Over 850,000 unnecessary C-sections are performed each year in Latin America (Belizán, Althabe, Barros, & Alexander, 1999). According to a recent annual report of the Sotomayor Maternity Hospital in Guayaquil, Ecuador, 58% of total births were cesarean (Junta de B., 2004). In comparison, the overall cesarean rate in the U.S. (which is also high according to medical recommendations) is reported to be about 27% (NCHS, 2003). Unnecessary cesarean sections have resulted in increased infection, hemorrhage, damage to abdominal and urinary tract organs, drug complications, prematurity, increased neonatal illness, and longer hospitalization (Sloan et al, 2000). These reported rates in Ecuador …

A Systematic Review Of Pregnancy Prevention Programs For Minority Youth In The U.S.: A Critical Analysis And Recommendations For Improvement, Sarah B. Maness, E R. Buhi

Journal of Health Disparities Research and Practice

African American and Latino youth experience disproportionate rates of both intended and unintended pregnancy in the United States. A public health priority to ameliorate the high rates among this population has been the creation and proposed expansion of pregnancy prevention programs designed specifically for minority youth. However, little is known about the role of incorporating cultural components into program curricula. To better understand the components and outcomes of existing programs for this population, this systematic review analyzed published outcome evaluations of adolescent pregnancy prevention programs for minority youth. This review of literature published from January 2002 to June 2012 and …

The Effect Of Robot-Child Interactions On Social Attention And Verbalization Patterns Of Typically Developing Children And Children With Autism Between 4 And 8 Years, Sudha Srinivasan, Anjana Bhat

Open Access Author Fund Awardees' Articles

Background: There is anecdotal evidence for the use of robots to facilitate prosocial behaviors such as joint attention and verbalization in children with Autism Spectrum Disorders (ASDs). However, there have been no normative data in typically developing children to evaluate the effects of robot-child interactions on social and communication skills. Objectives: The aim of our study was to evaluate the changes in social attention and verbalization skills of 15 typically developing (TD) children, using a structured 8-session imitation protocol within a robot-adult-child context. We further extended this imitation protocol to two children with ASDs. Methods: Pretest, session1, session 4, session …

Overweight And Obesity: Can We Reconcile Evidence About Supermarkets And Fast Food Retailers For Public Health Policy?, Deborah Viola, Peter S. Arno, Andrew R. Maroko, Clyde B. Schechter, Nancy Sohler, Andrew Rundle, Kathryn M. Neckerman, Juliana Maantay

NYMC Faculty Publications

The aim of this study is to determine whether access to fast food outlets and supermarkets is associated with overweight and obesity in New York City neighborhoods. We use a Bayesian ecologic approach for spatial prediction. Consistent with prior research, we find no association between fast food density and overweight or obesity. Consistent with prior research, we find that supermarket access has a salutary impact on overweight and obesity. Given the lack of empirical evidence linking fast food retailers with adverse health outcomes, policymakers should be encouraged to adopt policies that incentivize the establishment of supermarkets and the modification of …

Efferent Copy And Corollary Discharge Motor Control Behavior Associated With A Hopping Activity, Wangdo Kim, António P. Veloso, Filipa João, Sean S. Kohles

Mechanical and Materials Engineering Faculty Publications and Presentations

Hoppers respond not only to stimuli from the ground surfaces but also to cues generated by their own behaviors. This leads to desensitization because although the afferent and reafferent signals have distinct causes, they are carried by the same sensory channels. From a behavioral viewpoint, it may be necessary to distinguish between signals from the two causes especially when monitoring changes in the external environment separate from those due to self-movement. We were able to separate afferent sensory stimuli from self-generated, reafferent signals using an action oriented perception system and dynamic programming approach. This effort addressed the question of how …

Population Cancer Risks Associated With Coal Mining: A Systematic Review, Wiley D. Jenkins, W. Jay Christian, Georgia Mueller, K. Thomas Robbins

Epidemiology and Environmental Health Faculty Publications

BACKGROUND: Coal is produced across 25 states and provides 42% of US energy. With production expected to increase 7.6% by 2035, proximate populations remain at risk of exposure to carcinogenic coal products such as silica dust and organic compounds. It is unclear if population exposure is associated with increased risk, or even which cancers have been studied in this regard.

METHODS: We performed a systematic review of English-language manuscripts published since 1980 to determine if coal mining exposure was associated with increased cancer risk (incidence and mortality).

RESULTS: Of 34 studies identified, 27 studied coal mining as an occupational exposure …

Spatially Explicit Modeling Of Schistosomiasis Risk In Eastern China Based On A Synthesis Of Epidemiological, Environmental, And Intermediate Host Genetic Data, Matthias Schrader, Torsten Hauffe, Zhijie Zhang, George M. Davis, Fred Jopp, Justin V. Remais, Thomas Wilke

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Schistosomiasis japonica is a major parasitic disease threatening millions of people in China. Though overall prevalence was greatly reduced during the second half of the past century, continued persistence in some areas and cases of re-emergence in others remain major concerns. As many regions in China are approaching disease elimination, obtaining quantitative data on Schistosoma japonicum parasites is increasingly difficult. This study examines the distribution of schistosomiasis in eastern China, taking advantage of the fact that the single intermediate host serves as a major transmission bottleneck. Epidemiological, population-genetic and high-resolution ecological data are combined to construct a predictive model capable …