Digital Commons Network^™

Predictors Of Aggression Among Adolescent Girls, Sarah Joy Park

Loma Linda University Electronic Theses, Dissertations & Projects

Women and girls will often deny what they feel and think to maintain their relationships. Silencing the self can be detrimental to the physical and mental health of teenage girls. This stifling of the self is related to depression, earlier first intercourse, eating disorders, and less relationship satisfaction. Girls who silence their voices are also likely to have difficulty expressing themselves when they feel angry. In this study we explored the relationship between silencing the self and physical, verbal, and indirect aggression. Our sample consisted of 88 teenage girls from two high schools, with a mean age of 16. They …

“Practice Basic Hygiene, And You’Ll Stay Healthy”: How Primary School Reading Textbooks Transmitted Cultural Education In The Soviet Union, Victoria Storozenko

University of South Florida (USF) M3 Publishing

Russia’s Cultural Revolution, beginning after the October Revolution in 1917, produced a broadly defined understanding of culture and cultural education at Russian schools that encompassed even basic hygiene and health. Drawing from postdoctoral research, this paper discusses the Cultural Revolution’s impact and its ideas on cultural education as presented in textbooks for 10-year general education schools in the Soviet Union. Discourse analysis revealed that the schoolbooks acted as an interface between a functional education system and changes in its surrounding environment, especially changes due to the Cultural Revolution. Amid today’s COVID-19 pandemic, the study’s findings raise several questions about what …

Understanding The Pathogenesis Of Renal Medullary Carcinoma, Melinda Soeung

Dissertations and Theses (Open Access)

Renal medullary carcinoma (RMC) is a lethal cancer that predominantly affects young individuals with sickle cell trait (SCT). It is not currently understood why RMC only affects certain individuals with SCT. We found that patients with RMC more frequently participated in high-intensity exercise than matched controls. Using mouse models of SCT, we demonstrated the significant increase of renal hypoxia in the right kidney following high- but not moderate-intensity exercise. We also demonstrated in cell culture studies that SMARCB1 is ubiquitinated for proteasome-mediated degradation in hypoxia, and the re-expression of SMARCB1 leads to compromised proliferation in renal cells specifically in the …

Treatment And Outcomes Of Soft Tissue Sarcoma Of Groin, Hip And Thigh: A Retrospective Review From A Tertiary Care Hospital, Masood Umer, Javeria Saeed, Zaid Ahmed Shamsi, Muhammad Usman Tariq

Section of Orthopaedic Surgery

Objective: To study the frequency of the thigh, hip and groin soft tissue sarcomas and retrospectively analyse the management, treatment results, and outcomes of these uncommon malignant tumours, in a tertiary care hospital of the city of Karachi.
Methodology: Data of soft tissue tumours registered from 2017-2018 was retrieved during January 2019 to March 2019 from Aga Khan University Hospital, Karachi bone and soft tissue tumour registry. A retrospective review was performed and all soft tissue tumour cases treated with surgical intervention (with adjuvant /neoadjuvant therapy) or palliative intention were included.
Results: Total 119 cases of soft tissue tumours (STS) …

Throwing Pebbles While Waiting: An Autoethnographic Exploration Of Mental Health And Colonialism, Kelly Limes Taylor, Rita Sørly, Bengt Karlsson

The Qualitative Report

In this article, three scholars jointly investigate questions of Western colonization and mental health. While their areas of interest and experience vary, the authors discuss oppression as a common thread connecting their ideas about mental health and its medicalization. In line with Toyosaki et al. (2009), the researchers did a community autoethnography, performing written dialogue as a dynamic research method. Using a sequential model, Kelly Limes Taylor wrote about her experience, passed it on to Rita Sørly and Bengt Karlsson. Karlsson added his story to the previous writing, and he passed it on to Sørly for further addition of stories. …

Levels Of Trust In Information Sources As A Predictor Of Protective Health Behaviors During Covid-19 Pandemic: A Uae Cross-Sectional Study, Maria J. Figueiras, Jihane Ghorayeb, Mariana V. C. Coutinho, João Marôco, Justin Thomas

All Works

Health information sources and the level of trust in a particular source may influence the subsequent adoption of advocated health behaviors. Information source preference and levels of trust are also likely to be influenced by sociodemographic (culture, age, gender) variables. Understanding these source-trust-behavior relationships across various national and cultural contexts is integral to improved health messaging. The present study identified the sources most frequently consulted to obtain information about COVID-19 during the pandemic's early stages in the United Arab Emirates (UAE). The study quantified levels of trust across an array of information sources, factoring in sociodemographic variables. Finally, the study …

Thanatechnology And The Living Dead: New Concepts In Digital Transformation And Human-Computer Interaction, Vural Özdemir, Simon Springer, Arif Ylldlrlm, Sehmus Biçer, Asllgül Kendirci, Semra Sardaş, Hakan Klllç, Nezih Hekim, Tanja Kunej, Kazlm Yalçln Arga, Kevin Dzobo, Wei Wang, Marius Geanta, Angela Brand, Mustafa Bayram

Research outputs 2014 to 2021

In a digital society, shall we be the authors of our own experience, not only during our lifetime but also after we die? We ask this question because dying and bereavement have become even harder, and much less private, in the digital age. New big data-driven digital industries and technologies are on the rise, with promises of interactive 3D avatars and storage of digital memories of the deceased, so they can continue to exist online as the "living dead"in a digital afterlife. Famous rock and roll icons like Roy Orbison, Frank Zappa, Ronnie James Dio, and Amy Winehouse have famously …

Mechanism Of Mechanical Vibration In Enhancing Orthodontic Retention, Brent A. Ito

Master's Theses (2009 -)

Introduction: Low-magnitude, high-frequency (LMHF) mechanical vibration is proven to be anabolic and can increase alveolar bone mass. The objectives of this study were to generate an orthodontic retention cell culture model and investigate the effects of LMHF mechanical vibration on human periodontal ligament fibroblast (HPLF) cells after orthodontic loading (retention) in vitro. Materials and Methods: HPLF cells were seeded at a density of 4x105/well in 6-well Flexcell culture plates (Day 0). On day 3, the cells were mechanically stretched (15% surface extension) for 1 hour to mimic orthodontic loading/tension in vitro. On day 5, the cells were randomly assigned to …

Sars-Cov-2 Viral Proteins Nsp1 And Nsp13 Inhibit Interferon Activation Through Distinct Mechanisms, Christine Vazquez, Sydnie E Swanson, Seble G Negatu, Mark Dittmar, Jesse Miller, Holly Ramage, Sara Cherry, Kellie A Jurado

Department of Microbiology and Immunology Faculty Papers

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a devastating global pandemic, infecting over 43 million people and claiming over 1 million lives, with these numbers increasing daily. Therefore, there is urgent need to understand the molecular mechanisms governing SARS-CoV-2 pathogenesis, immune evasion, and disease progression. Here, we show that SARS-CoV-2 can block IRF3 and NF-κB activation early during virus infection. We also identify that the SARS-CoV-2 viral proteins NSP1 and NSP13 can block interferon activation via distinct mechanisms. NSP1 antagonizes interferon signaling by suppressing host mRNA translation, while NSP13 downregulates interferon and NF-κB promoter signaling by limiting TBK1 …

The Effect Of Fluid Flow Shear Stress And Substrate Stiffness On Yes-Associated Protein (Yap) Activity And Osteogenesis In Murine Osteosarcoma Cells, Thomas R. Coughlin, Ali Sana, Kevin Voss, Abhilash Gadi, Upal Basu-Roy, Caroline M. Curtin, Alka Mansukhani, Oran D. Kennedy

Publications and Research

Osteosarcoma (OS) is an aggressive bone cancer originating in the mesenchymal lineage. Prognosis for metastatic disease is poor, with a mortality rate of approximately 40%; OS is an aggressive disease for which new treatments are needed. All bone cells are sensitive to their mechanical/ physical surroundings and changes in these surroundings can affect their behavior. However, it is not well understood how OS cells specifically respond to fluid movement, or substrate stiffness—two stimuli of relevance in the tumor microenvironment. We used cells from spontaneous OS tumors in a mouse engineered to have a bone-specific knockout of pRb-1 and p53 in …

Health Care Disparities Around The Globe, Brianna N. Hodak, Renee Nicholson

Mountaineer Undergraduate Research Review

In Honduras, there are only 0.8 physicians for every 1,000 citizens, creating a nearly insurmountable barrier on the ability to access health care for the impoverished lower and middle classes. Various health care models that a country adopts directly affects the quality of life of its citizens, including access to care and clean water, advocacy of preventative methods, and life expectancy. By analyzing models, such as the “Out-of-Pocket”, Beveridge, and Bismarck models, one can see that there are positive and negative aspects in every system. It can also be seen that the American Healthcare system is also in dire need …

Destination Shapes Antibiotic Resistance Gene Acquisitions, Abundance Increases, And Diversity Changes In Dutch Travelers, Alaric W D'Souza, Manish Boolchandani, Sanket Patel, Gianluca Galazzo, Jarne M Van Hattem, Maris S Arcilla, Damian C Melles, Menno D De Jong, Constance Schultsz, Combat Consortium, Gautam Dantas, John Penders

2020-Current year OA Pubs

BACKGROUND: Antimicrobial-resistant bacteria and their antimicrobial resistance (AMR) genes can spread by hitchhiking in human guts. International travel can exacerbate this public health threat when travelers acquire AMR genes endemic to their destinations and bring them back to their home countries. Prior studies have demonstrated travel-related acquisition of specific opportunistic pathogens and AMR genes, but the extent and magnitude of travel's effects on the gut resistome remain largely unknown.

METHODS: Using whole metagenomic shotgun sequencing, functional metagenomics, and Dirichlet multinomial mixture models, we investigated the abundance, diversity, function, resistome architecture, and context of AMR genes in the fecal microbiomes of …

Construct Validity And Invariance Assessment Of The Social Impacts Of Occupational Heat Stress Scale (Siohss) Among Ghanaian Mining Workers, Victor F. Nunfam, Ebenezer Afrifa-Yamoah, Kwadwo Adusei-Asante, Eddie J. Van Etten, Kwasi Frimpong, Isaac Adjei-Mensah, Jacques Oosthuizen

Research outputs 2014 to 2021

Heat exposure studies over the last decade have shown little attention in assessing and reporting the psychometric properties of the various scales used to measure impacts of occupational heat stress on workers. A descriptive cross-sectional survey including 320 small- and large-scale mining workers was employed to assess the construct validity of the social impacts of occupational heat stress scale (SIOHSS) in the Western Region of Ghana in 2017. A confirmatory factor analysis (CFA) and invariance analysis were carried out using AMOS version 25 and statistical product and service solutions (SPSS) version 26 to examine the model fit and establish consistency …

Component Causes Of Infectious Bovine Keratoconjunctivitis—Non-Moraxella Organisms In The Epidemiology Of Infectious Bovine Keratoconjunctivitis, John Dustin Loy, Kristin A. Clothier, Gabriele Maier

School of Veterinary and Biomedical Sciences: Faculty Publications

• Non-Moraxella organisms are associated with infectious bovine keratoconjunctivitis (IBK).

• Mycoplasma bovoculi can cause conjunctivitis and has a potential role in IBK pathogenesis.

• Other Non-Mycoplasma agents can cause disease that resembles IBK but is clinically different.

• Genomics and molecular technology are advancing research in this area.

• Classification and determination of pathogenesis potential of these organisms may be better understood through metagenomics and whole genome sequencing.

Preventing Central Line Associated Bloodstream Infections In An Adult Intensive Care Unit, Monica Shaw

Master's Projects and Capstones

Central line associated blood stream infections (CLABSI) are considered preventable healthcare acquired infections, and are associated with significantly increased morbidity, mortality, and length of hospital stay. The CLABSI rate in an inpatient unit is a meaningful metric in relation to the safety and quality of care in that microsystem. This quality improvement project examines the efficacy of a CLABSI prevention bundle in reducing CLABSI events and improving adherence to central line care policy within a medical surgical adult intensive care unit. The target areas the bundle aimed to improve were unit processes, awareness of CLABSI and central line policies, and …

Androgen Receptor, Although Not A Specific Marker For, Is A Novel Target To Suppress Glioma Stem Cells As A Therapeutic Strategy For Glioblastoma, Nan Zhao, Fei Wang, Shaheen Ahmed, Kan Liu, Chi Zhang, Sahara J. Cathcart, Dominick J. Dimaio, Michael Punsoni, Bingjie Guan, Ping Zhou, Shuo Wang, Surinder K. Batra, Tatiana K. Bronich, Tom K. Hei, Chi Lin, Chi Zhang

Journal Articles: Biochemistry & Molecular Biology

Targeting androgen receptor (AR) has been shown to be promising in treating glioblastoma (GBM) in cell culture and flank implant models but the mechanisms remain unclear. AR antagonists including enzalutamide are available for treating prostate cancer patients in clinic and can pass the blood-brain barrier, thus are potentially good candidates for GBM treatment but have not been tested in GBM orthotopically. Our current studies confirmed that in patients, a majority of GBM tumors overexpress AR in both genders. Enzalutamide inhibited the proliferation of GBM cells both in vitro and in vivo. Although confocal microscopy demonstrated that AR is expressed …

Teaching Philippine Literature And Illness: Finding Cure In Humanities, John Paolo Sarce

English Faculty Publications

Health and illness as themes are uncommonly being touched in literature classrooms. Other than the lack of interdisciplinary studies or specialists in this field in the Philippines; often teachers are also confronted with tons of materials that they are either overwhelmed to teach or find it difficult to deliver on their classes. This is the goal of this paper; help teachers gain confidence and basic knowledge of teaching literature that discusses health and illness especially at this time of history. Helping both teachers and students to understand and appreciate literature as a space for developing empathy while also honing their …

Intangible Cultural Heritage: A Benefit To Climate-Displaced And Host Communities, Gül Aktürk, Martha B. Lerski

Publications and Research

Climate change is borderless, and its impacts are not shared equally by all communities. It causes an imbalance between people by creating a more desirable living environment for some societies while erasing settlements and shelters of some others. Due to floods, sea level rise, destructive storms, drought, and slow-onset factors such as salinization of water and soil, people lose their lands, homes, and natural resources. Catastrophic events force people to move voluntarily or involuntarily. The relocation of communities is a debatable climate adaptation measure which requires utmost care with human rights, ethics, and psychological well-being of individuals upon the issues …

Correlation Between Servant Leadership And Organizational Commitment Within An Academic Health Center, Cheryl Bellamy

Servant Leadership: Theory & Practice

Correlation Between Servant Leadership and Organizational Commitment

Abstract

This paper presents an overview of a study of the relationship between servant leadership and organizational commitment. The study included a convenience sample of 84 full and part-time employees of a health professions education unit within an academic health center. Participants were surveyed using the Executive Servant Leadership Scale (ESLS) to assess servant leadership and the Klein Unidimensional Target-free (KUT) instrument to assess organizational commitment. Data analysis was conducted using Kendall’s tau-b and Spearman’s rho. Results showed that there is a significant positive relationship between servant leadership and organizational commitment.

Keywords: Servant …

Biostimulatory Effects Of Low-Intensity Pulsed Ultrasound On Rate Of Orthodontic Tooth Movement And Associated Pain, Applied At 3-Week Intervals: A Split-Mouth Study, Irfan Qamruddin, Mohammad Khursheed Alam, Verda Mahroof, Meenaz Karim, Mubassar Fida, Mohd Fadhli Khamis, Adam Husein

Section of Dental-Oral Maxillofacial Surgery

Objective: Low-intensity pulsed ultrasound (LIPUS) is a noninvasive modality to stimulate bone remodeling (BR) and the healing of hard and soft tissues. This research evaluates the biostimulatory effect of LIPUS on the rate of orthodontic tooth movement (OTM) and associated pain, when applied at 3-week intervals.
Methods: Twenty-two patients (11 males and 11 females; mean age 19.18 ± 2.00 years) having Angle's Class II division 1 malocclusion needing bilateral extractions of maxillary first bicuspids were recruited for this split-mouth randomized clinical trial. After the initial stage of alignment and leveling with contemporary edgewise MBT (McLaughlin-Bennett-Trevisi) prescription brackets (Ortho Organizers, Carlsbad, …

Molecular And Genetic Studies Of Robo2 Transcriptional Regulation In The Central Nervous System Of Drosophila Melanogaster, Muna Abdal Rahim Abdal Rhida

Graduate Theses and Dissertations

Drosophila Robo2 axon guidance receptor is a member of the evolutionarily conserved Roundabout (Robo) protein family that is involved in directing axons that cross the midline to the other side of the animal body. Robo2 roles mainly depend on two factors: The functional domains of the Robo2 protein, which is extensively studied, and the dynamic transcription of robo2 in various subsets of cells throughout embryogenesis which is not fully understood. Thus, knowing robo2 enhancers that transcriptionally regulate robo2 during embryogenesis is significant. To investigate robo2 potential enhancers, we screened 17 transgenic lines of Drosophila that were generated by Janelia Research …

Language Abilities Of Children Who Qualify For Both Speech And Language Therapy And Play Therapy, Rylee Atkins

Rehabilitation, Human Resources and Communication Disorders Undergraduate Honors Theses

Play is an essential role in the development of children’s language and social-emotional well-being. Intervention methods with the use of play are used by both registered play therapist and speech-language pathologists. This study aims to explore if students who have met the eligibility requirements for speech-language therapy services are also eligible for child-centered play therapy services, as well as examine if students who qualify for both services have common characteristics. Findings demonstrated that students who qualified for CCPT and had individualized education plans (IEPs) for speech-language services had significantly lower poor peer social skills, as determined by teacher’s rating scores, …

Recovering From Substance Abuse In Arkansas: The Accessibility And Affordability Of Drug Treatment Programs, Whitney King

Graduate Theses and Dissertations

This thesis is going to examine how people recover from drug addiction and see if there are any similarities due to their socioeconomic statuses at the time of recovery. This research addresses the following questions: How accessible and affordable are drug addiction recovery programs and rehabilitation facilities in Arkansas for mid- to low-income individuals? What are the social costs for people who can’t obtain drug rehabilitation services? The goal of this research is to explore whether there is a lack of affordable recovery programs in the state of Arkansas. This project utilizes survey responses as well as in-depth interviews with …

Vertical Transmission Of Zika Virus In An Opossum Model, Dionn Carlo Silva

Theses and Dissertations

This study will identify Brazilian ZIKV infection in the offsprings of mated, inoculated Monodelphis domestica females. Unlike non-human primates (NHP) and transgenic mice, M. domestica provides an opportunity to study ZIKV infection in a novel animal model possibly useful for in-utero studies. M. domestica has also been used in cancer and dietary research with varying degrees of success. ZIKV infection will be identified using antibody staining and in situ hybridization. The expected result of this study is that ZIKV will be identified in various tissues and reveal that ZIKV is transmitted vertically in this animal model. The significance of this …

Controlling Dentistry-Related Musculoskeletal Disorders With Ergonomic Interventions In Lahore, Pakistan, Marriyam Nasar, Farwa Rubab, Hazik Bin Shahzad, Minam Qureshi, Maham Shahid, Pakiza Batool

Makara Journal of Health Research

Background: Musculoskeletal disorders (MSDs) usually result from a prolonged static position and repetitive movements. A comfortable environment, appropriate working position, and multiple short breaks could alleviate MSDs. While the occasional back or neck ache is not a cause for alarm, regularly occurring pain or discomfort, if ignored, may further develop into an injury or career-ending disability.

Methods: A total of 370 dentists were selected from two dental hospitals and multiple dental clinics in Lahore, Pakistan. Current MSDs were recorded with the Standardized Nordic Questionnaire (SNQ). Information sheets containing dental ergonomics and back and tendon-gliding exercises were distributed among …

“Ichachu”: Ontological Diversity For Assembling Common Futures, Kaliana Conesa

The International Journal of Ecopsychology (IJE)

The present work explores the role of discursive analyses of language as potent elements in networks of discourse and practice. A particular focus is with how language functions in multiple, overlapping registers, and how this affects its ability to motivate and coalesce diverse actors into communities of practice. In particular, usages of sovereignty, food sovereignty, and ontology are explored as a means for understanding the process of cross-cultural eco-social action. Fundamental to these analyses is the precept that registers of language represent an epistemic diversity always operating in collaborations for biocultural sustainability. By “eco-social action,” it is meant any practice, …

In The Spirit Of St. Peter Claver: Social Justice And Black Catholicism In San Antonio, Philip Lampe Ph.D.

Verbum Incarnatum: An Academic Journal of Social Justice

The editors want to take the space reserved for the abstract to say that this is the final piece of research that Phil Lampe completed before his passing. We publish it here posthumously in tribute to Phil’s tireless work for social justice, as editor of Verbum Incarnatum, as researcher of social-justice efforts in South Texas and Mexico, and as an educator committed to inspiring students to pursue justice in their lives outside the academy.

Social Justice In The Cigar Factory: The Finck Cigar Strikes, 1933-1935, Roger Barnes

Verbum Incarnatum: An Academic Journal of Social Justice

No abstract provided.

A Participatory Action Research Study Of Police Interviewing Following Crisis Intervention Team Training, Maria Felix-Ortiz, Catherine Steele, Marisa Deguzman, Georgen Guerrero, Melissa Graham

Verbum Incarnatum: An Academic Journal of Social Justice

Estimates vary, but a third to one half of individuals shot and killed by police have a mental illness or disability, and many who are taken into custody languish in county jails where no treatment for their illness is available. The Crisis Intervention Team (CIT) model is an increasingly important adjunct to U.S. police training because it de-escalates tense situations, diverts people with mental illness away from jail and into treatment, and can reduce the risk of civilian deaths during a police encounter. As such, it is a strategy for reducing the social injustice of incarceration or deaths of people …

Promises Endure: Historical Views Of Nursing Faculty, Laura R. Muñoz

Verbum Incarnatum: An Academic Journal of Social Justice

Lessons learned from the history of an organization are valuable. This is especially true for an organization with the legacy held by the Ila Faye Miller School of Nursing and Health Professions at the University of the Incarnate Word. Memories recounted by nursing faculty were collected to enhance information provided in the two-volume chronicle written by Sister Patrice Slattery in 1995 entitled, “Promises to Keep” and the last history of the school, “The Story of One School of Nursing” written by Sister Charles Marie Frank in 1976.