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Long Work Hours, Suboptimal Diabetes Management, And Differences By Sex And Race/Ethnicity, Nhanes (2011-2018), Tailisha Gonzalez, Margrethe Horlyck-Romanovsky, Terry T.-K. Huang, Sandra E. Echeverria

Publications and Research

In the United States (US), occupational segregation by sex and race/ethnicity can contribute to health disparities. Although work schedule characteristics have been previously linked to elevated cardiovascular risk, little is known about the effects on chronic disease management in women and minoritized workers. We examined the association between work hours and diabetes management among US workers, testing for differences by sex and race/ethnicity. We utilized 2011–2018 National Health and Nutrition Examination Survey (NHANES) data on working adults (age ≥20 years) with diagnosed diabetes (n = 1041). Suboptimal diabetes management was defined as HbA1c ≥7%. Work hours were categorized per WHO …

Pharmacological Treatment Options For Vasoplegia Syndrome During And After Cardiopulmonary Bypass: A Scoping Review, Bradley Darby

Student Works

ABSTRACT

2: Structured summary

Background

Vasoplegia Syndrome (VS) is a form of distributive shock that is characterized by profound hypotension, low systemic vascular resistance, and high to normal cardiac output during/after cardiopulmonary bypass. VS is associated with increased mortality, morbidity, and length of stay in the intensive care unit.

Objective

The main objectives of this scoping review are to note the available treatment options, characterize potential risk factors, and identify gaps in knowledge for vasoplegia syndrome during and after cardiopulmonary bypass.

Method

This scoping review utilized the Preferred Reporting Items for Systematic reviews and MetaAnalyses extension for Scoping Reviews (PRISMA-ScR) …

Astrocyte Circadian Regulation In Neurodegeneration: In Vivo Bmal1 Occupancy Mapping Using Macs-Calling Cards, India Reiss

Arts & Sciences Graduate Student Theses and Dissertations

Astrocytes maintain neuronal homeostasis through cellular programs that are frequently disrupted early in neurodegenerative disease, many of which are regulated by the circadian clock. The core clock transcription factor BMAL1 is required for normal astrocyte function, yet whether its regulatory activity is altered during neurodegeneration remains unclear. BMAL1 expression changes in disease are often inconsistent, suggesting that transcription factor binding, rather than expression, may be a more informative readout of BMAL1 function. We used a Cln3Δex7/8 model of neurodegeneration, which exhibits early astrocyte dysfunction prior to widespread neuronal loss, to test whether degenerative pathology reprograms BMAL1 binding in astrocytes. We …

Keratopigmentation: A Comparative Review Of Safety, Indications, And Clinical Outcomes, Emmy L. Colon Alamo

Undergraduate Scholarship and Creative Works

Throughout the years, there has been an upsurge in the quantity of cosmetic procedures aimed at changing eye color or appearance. This trend raises significant concerns about patient safety and visual health, as although many methods are promoted worldwide, their efficacy and, most importantly, safety varies greatly. This review looks at the safety of procedures that alter eye color or appearance, focusing mainly on cosmetic keratopigmentation, which is currently the only legally accepted method for changing eye color in the U.S.

A review of clinical studies was conducted to evaluate the outcomes and complications related to keratopigmentation. Then, these findings …

Barriers Of Animal Assisted Therapy, Taylor Blanchard, Amy Lyons-Brown

Spring 2026 OTD Capstone Symposium

This study employs a mixed-methods design, integrating online surveys, semi-structured interviews, and clinical observations to examine the use of animal-assisted therapy (AAT) within occupational therapy practice. The primary objectives are to characterize the demographics of occupational therapists and therapy animals engaged in AAT, identify barriers to its implementation, and evaluate the resources currently available to support practitioner knowledge and competency. By addressing these areas, the study seeks to clarify existing gaps in education and practice, with the broader goal of strengthening the evidence base and enhancing the accessibility, consistency, and impact of AAT in occupational therapy.

Memory Processes In Older Adults With Hearling, Camryn L. Kirkham

AuD Capstone Projects - Communication Sciences and Disorders

Emerging research has shown links between hearing loss in older adults and memory declines; however, findings remain mixed. The present study examined differences in memory performance between older adults with hearing loss and normal-hearing peers, as well as associations between hearing ability and memory. An exploratory analysis of associations between high-frequency hearing ability and memory performance was also conducted. Participants included 38 older adults with hearing loss (n=20) and normal hearing (n=18) who completed audiologic testing and memory tasks assessing working, semantic, and episodic memory. Contrary to expectations, no significant group differences in memory performance were observed between the hearing …

Geographical And Anatomical Microbiome Variation In Invasive Green Iguanas (Iguana Iguana), Amanda A. Diaz

All HCAS Student Capstones, Theses, and Dissertations

The common green iguana (Iguana iguana) was introduced to South Florida in 1965 and has since been an especially pernicious threat both environmentally and economically. This highly invasive species is also expanding in range and populations at an astonishing rate. Understanding how this reptile is able to adapt and thrive in novel environments is of imperative need in order to begin managing their disruptive populations. Notwithstanding their negative impacts and significance, the microbiome of wild populations has not yet been characterized. Here, using 16S ribosomal RNA gene sequencing, this study is the first to characterize the microbiome composition …

First, Do No Trend: Aligning Parenteral Lipid Therapy With Physiology And Evidence In Neonates, Parvesh Mohan Garg, Srinivas Bolisetty, Camilia R Martin, Muralidhar H Premkumar

Faculty, Staff and Students Publications

Lipid injectable emulsions (ILE) are essential components of parenteral nutrition in neonatal intensive care units. Over the past two decades, the expanded availability of ILE has led to rapid changes in clinical practice, largely driven by concerns about intestinal failure–associated liver disease. Despite these evolving trends, the evidence supporting one ILE over another remains limited and nuanced. Importantly, no currently available ILE replicates the intrauterine supply of critical long-chain polyunsaturated fatty acids, particularly arachidonic acid and docosahexaenoic acid, both of which decline postnatally regardless of emulsion type. Neonates requiring ILE represent a heterogeneous population of preterm and term infants, with …

Maternal Inflammation Alters Nuclear And Mitochondrial Dna Methylation Patterns In Neonatal Brain Monocytes, Andrew Ebenezer, Jonathan Hicks, Brooke Hollander, Alexander Hone, Mona Batish, Robert Akins, Adam Marsh, Elizabeth Wright-Jin

Department of Medicine Faculty Papers

Neonatal hypoxic ischemic encephalopathy (HIE) is a common birth complication that can cause death or lifelong disabling conditions like cerebral palsy, epilepsy, and autism. It is well established that maternal infection and inflammation are significant risk factors for HIE but reasons for this increase in neurological risk to the offspring remain unknown. Inflammation or infection are associated with epigenetic changes and may contribute to the increased risk of neurodevelopmental disability in exposed offspring. Here, we analyzed and compared DNA methylation patterns in brain monocytes isolated from control, maternal immune activation (MIA), and an inflammation sensitized HIE (IS-HIE) CF-1 mouse model …

Dnp Final Report: Can Implementing A Mindfulness-Based Program Help Reduce Stress In Nursing Students?, Shelby Devreeze Msn, Rn, Cpn, Cne-Cl

DNP Final Reports

Stress among nursing students is a well-documented problem that contributes to physical, mental, and emotional issues, substance abuse, and program dropout. A mindfulness-based stress reduction program was implemented with nursing students to evaluate its impact on perceived stress levels over a five-week period. A review of evidence-based articles provides strong evidence that this intervention correlates with reduced reported stress. An MBSRP was implemented with nursing students who completed a Perceived Stress Scale 10 (PSS-10) before the intervention and again after five weeks.

Results from this project showed a statistically significant reduction (t=2.725, p=0.025) in stress among the nursing student population …

Robust Non-Invasive Cardiac Index Prediction Via Feature Integration And Data-Augmented Neural Networks, Chih-Hao Chang, Mei-Ling Chan, Yu-Hung Fang, Po-Lin Huang, Tsung-Yi Chen, Tsun-Kuang Chi, I Elizabeth Cha, Tzong-Rong Ger, Kuo-Chen Li, Shih-Lun Chen, Liang-Hung Wang, Jia-Ching Wang, Patricia Angela R. Abu

Department of Information Systems & Computer Science Faculty Publications

Concurrent with the rising consumption of ultra-processed, high-calorie diets and the decline in physical activity, obesity and related cardiovascular conditions among young adults have continued to increase, becoming an important global public health concern. This study integrates non-invasive Internet of Things (IoT) sensing devices, including the TERUMO ES-P2000 blood pressure monitor (Terumo Corp., Tokyo, Japan) and the PhysioFlow PF07 Enduro cardiac hemodynamic analyzer (Manatec Biomedical, Poissy, France), with an artificial neural network (ANN) for cardiac index (CI) prediction. Through appropriate data preprocessing and model training strategies, the generalization ability and stability of the proposed CI prediction model were significantly enhanced. …

Role Of Occupational Therapy In Hippotherapy And Therapeutic Riding: A Mental Health Perspective, Ava Morrison

Capstone Projects

The purpose of my doctoral capstone experience (DCE) was to gain knowledge about the unique role that occupational therapy (OT) plays in equine-assisted therapy at the Cheff Therapeutic Riding Center, with an emphasis on Therapeutic Riding. Equine-assisted therapy, including hippotherapy and therapeutic riding, is an emerging area of occupational therapy practice that promotes physical, cognitive, emotional, and social well-being through structured interactions with horses. Despite growing evidence supporting the therapeutic benefits of equine-assisted interventions, confusion remains regarding the distinctions between hippotherapy and therapeutic riding, highlighting the need for increased education and advocacy within the field. In addition, there is a …

Herbal Medicine Interference With Continuous Glucose Monitoring System In Diabetes Management: A Case Report, Julia Lees, Haley Johnson, Atefeh Bagherpanah, Timbreia Brown, Deniz Karaca, Tamaya Merrell

Research Day

Continuous glucose monitoring (CGM) systems have transformed diabetes management through improved glycemic control, leading to decreased adverse events such as cardiovascular disease, neuropathy, retinopathy and nephropathy. However, there are documented, known interactions with several commonly used substances that are available over the counter, such as acetaminophen, aspirin, and Vitamin C, that affect the accuracy of CGM glucose readings. The Food and Drug Administration (FDA) released an alert November 2025 regarding incorrect low glucose readings associated with the Freestyle Libre CGM system after the manufacturer received 736 severe adverse events and seven deaths related to this issue. The FDA warns that …

From Zebra Bite To The Operating Room: Discussion Of The Management Of Equine Bite Wounds, Kavya Suryadevara, Harshita Yepuri, Saad Rahman, Milo Paman, Gehrig Ornelas, L. Michael Waters Jr

Research Day

Animal bites, particularly those from cats and dogs, are well characterized in emergency and surgical care. Equine animal bites, however, are rare and may be underestimated in severity. The genus Equus includes animals such as horses, donkeys, and zebras, with members sharing similar dental and digestive anatomy as well as comparable musculoskeletal traits. These animals generate significant crushing forces, often causing deep soft-tissue injury, devitalization, and extensive contamination with complex oral flora. For surgeons, such wounds present challenges in assessment, irrigation, debridement, and closure, as well as antimicrobial selection to prevent infection. Despite potential severity, equine bite cases are infrequently …

Zoonotic Streptococcus Equi Subspecies Epidemicus Bacteremia With Prosthetic Joint Injection And Dvt In An Elderly Patient: A Case Report And Literature Review, Bhavik Singh, Zoë M. Rushetsky, Zoheb I. Sulaiman, Eileen M. Raynor

Research Day

Introduction

Streptococcus equi subspecies zooepidemicus (SEZ) is a beta-hemolytic group C streptococcus commonly found in the upper respiratory tract of horses and other animals. Although SEZ is a frequent cause of equine “strangles,” human infection is exceptionally rare and associated with direct animal contact or consumption of unpasteurized animal products. Human SEZ infections have been reported to present with bacteremia, septic arthritis, endocarditis, or meningitis—particularly in immunocompromised individuals—but involvement of prosthetic joints is scarcely described in the literature. This case highlights an unusual zoonotic presentation of SEZ bacteremia in an elderly male with frequent equine exposure that was complicated by …

Evaluation Of A Blast Pressure Wave Apparatus To Model Traumatic Brain Injury In Rodents, Nolan Gillihan, Diana Peterson

Research Day

INTRODUCTION Traumatic brain injury resulting from blast pressure waves is a significant concern, particularly among military personnel. This study aims to evaluate a blast pressure wave apparatus designed to simulate human-like traumatic brain injury in rodents, assessing both physiological and behavioral outcomes.

METHODS Rodents (Long Evans rats and CB57B/SMN2 mice) were exposed to a single 20 psi blast pressure wave using the newly developed apparatus. Pre- and post-exposure assessments included several behavioral tests: tinnitus, depression, and motor function. Control groups were exposed solely to an equivalent blast sound, but not the pressure wave of the device. Data was analyzed to …

Effects Of Probiotic Supplementation On Symptoms In Teenagers Ages 13-18 With Inflammatory Skin Conditions, Katelyn S. Walker, Jessica Rosen, Matilde Belfiore

Department of Nutrition Student Projects

Teenagers between the ages of 13 and 18 are particularly susceptible to inflammatory skin disorders such as acne vulgaris and atopic dermatitis, which can have a detrimental effect on their physical and mental health. Emerging evidence highlights the importance of the gut-skin axis, indicating that the makeup of the gut microbiota affects both skin health and systemic inflammation. Adolescent-specific research is still limited even though probiotic supplementation, especially Lactobacillus strains, has demonstrated anti-inflammatory effects in laboratory, animal, and small clinical studies.

The purpose of this experimental study is to determine whether oral probiotic supplementation improves inflammatory skin condition symptoms in …

An Emerging Approach To Ibd Treatment: Personalized Nutrition Through Gut Microbiome Optimization., Kafayat Yusuf, Thomas M. Attard, Mazin Al-Kasspooles, Shahid Umar

Manuscripts, Articles, Book Chapters and Other Papers

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract characterized by relapsing and remitting disease activity. Despite decades of research, a definitive cure for IBD remains elusive, as cycles of remission and flare-ups mark the disease course and often relies on long-term pharmacologic and supportive strategies. Increasing evidence indicates that diet and nutrition play an important role in modulating the outcomes of IBD. Although a wide range of dietary interventions has been explored, no universally effective approach has been established. Investigations have also proven that different dietary interventions can significantly affect clinical outcomes by altering gut …

Galen Of Pergamum: Life, Literature, And Legacy, Elyse Rogers

Ex Sapientia Loqui

Galen of Pergamum was a second-century physician whose work had an enduring impact on the field of medicine. His extensive writings were the primary reference and teaching materials for the medical community for over a millennium. While his ideas were revolutionary for his time, they were eventually outdated. Nevertheless, there was a continued reliance on his authority, which hindered scientific advancement. Galen both advanced the world of medicine with his emphasis on observational analysis and constrained its progress through the profound dominance of his theories.

This paper aims to understand the life of Galen and the significance of his work …

Brain Delivery Of Antibody-Derived Biologicals For Alzheimer’S Disease: An Updated Narrative Review, Rachita K. Sumbria, Ruben J. Boado

Pharmacy Faculty Articles and Research

Antibodies directed against β-amyloid (Aβ) have been developed for the treatment of Alzheimer’s disease (AD). However, the in vivo central efficacy is reduced by the poor penetration of antibodies across the blood–brain barrier (BBB). In addition, these antibodies have been associated with adverse effects like amyloid-related imaging abnormalities. Thus, the development of new antibody-based therapies for AD with improved transport across the BBB may improve efficacy and reduce adverse effects. Antibodies targeting the BBB transferrin receptor (TfR) are able to cross the BBB through receptor-mediated transcytosis, producing a global distribution throughout the brain. Along the same line, bispecific antibodies directed …

Effects Of Gnrh And Hcg Administration On Conception Rate And The Subsequent Estrous Cycle On Day 12 Following Artificial Insemination In Holstein Cows, Mustafa Hi̇lmi̇ Yaranoğlu, Hüseyi̇n Erdem

Turkish Journal of Veterinary & Animal Sciences

The present study investigates the effects of gonadotropin-releasing hormone (GnRH) and human chorionic gonadotropin administration on the conception rate of cows 12 days after artificial insemination (AI). Included in the study were 150 high milkyielding Holstein cows housed under the same husbandry and feeding conditions. All had calved at least once between the ages of 2.5 and 6 years, and were between 90 and 220 days in milk. In accordance with the farm’s reproductive management approach, a controlled internal drug release (CIDR) device was inserted into the vagina concurrent with a GnRH injection (day 0), and the device was removed …

Neuropathological Hallmarks During The Chronic Phase Of Ischemic Stroke In Mice And Humans, Romeesa Khan, Gary Guzman, Trang Do, Patrick Devlin, John Ahn, Chunfeng Tan, Venugopal Reddy Venna, Sean P Marrelli, Haniyeh Koochak, Claudia M Di Gesù, Anthony Flores, Louise D Mccullough, Rodney M Ritzel

Faculty, Staff and Student Publications

Background: Advances in acute stroke care, including endovascular thrombectomy and improved neurocritical management, have increased survival after ischemic stroke. However, stroke remains a leading cause of long-term disability, with many survivors experiencing persistent neurological and cognitive impairments. The chronic neurological consequences of stroke, particularly its potential to accelerate brain aging, remain poorly understood.

Methods: We examined chronic neurobehavioral changes at 2 and 6 months after middle cerebral artery occlusion in male C57Bl/6 mice. Behavioral assessments included the open field test (OFT), novel object recognition test (NORT), fear conditioning (FC), nesting activity, and tail suspension testing. Transcriptomic profiling was performed using …

Age-Related Estimates Of Genetic Parameters For Growth And Ultrasonic M. Longissimus Thoracis Et Lumborum Muscle Traits In Eşme Lambs, İbrahi̇m Cemal, Orhan Karaca, Onur Yilmaz, Nezi̇h Ata

Turkish Journal of Veterinary & Animal Sciences

The growth performance and ultrasonic M. longissimus thoracis et lumborum (LTL) muscle traits of 2397 Eşme lambs raised in the Eşme district of Uşak province, an important lamb production area in Western Anatolia, were evaluated at 3 months (n = 1690) and 5 months (n = 707) of age. The average age of the lambs at the time of the first measurement (at weaning) was 100.15 days, and 152.37 days at the second. At 3 months of age, the average live weight (LW) was 29.34 kg and the average daily gain (ADG) was 248.35 g/day. By month 5, the LW …

Morphology And Histology Of The Developing Ovary In Malaysian Village Chicken (Gallus Gallus Domesticus) Chicks, Nur Athirah Lope Abdul Rashid, Mazlina Mazlan, Intan Shameha Abdul Razak, Rozaini Mohd Zohdi, Awang Hazmi Awang Junaidi

Turkish Journal of Veterinary & Animal Sciences

The Malaysian village chicken (MVC; Gallus gallus domesticus) is an indigenous breed derived from the red junglefowl (Gallus gallus), exhibiting slower growth and reproductive rates. The MVC plays an important ecological role in local farming systems and represents a valuable genetic resource. However, detailed information on ovarian development in this breed remains limited. This study provides the first comprehensive morphological and histological characterization of the developing ovary in MVC chicks. A total of 20 chicks aged 1, 2, 4, and 8 weeks (n = 5 per age group) were examined. These MVC chicks possessed a single functional left ovary positioned …

Effects Of Preslaughter Fasting On Ph And Bacterial Contamination In Akkaraman And Anatolian Merino Sheep, Sai̇m Boztepe, Özcan Şahi̇n, Talha Demi̇rci̇, Gi̇zem Coşkun, İbrahi̇m Ayteki̇n, İsmai̇l Keski̇n

Turkish Journal of Veterinary & Animal Sciences

The present study investigates the effects of the preslaughter fasting on pH and bacterial contamination in Akkaraman and Anatolian Merino sheep. Included in the study were 10 Akkaraman and 10 Anatolian Merino sheep (n = 20) that were fasted for 24 h prior to slaughter, and a further 10 Akkaraman and 10 Anatolian Merino sheep (n = 20) that continued to be fed until slaughter as a control group. The total mesophilic aerobic bacteria (TMAB) measured at 0 and 24 h in the fasting Akkaraman and Anatolian Merino sheep were 4.87/4.79 and 4.75/5.57 log CFU/g, respectively, and the corresponding Enterobacteriaceae …

The Effects Of Sodium Perborate Tetrahydrate On Digestibility And Nutrient Transporters In Rats, Büşra Özmen, Emre Şahi̇n, Muhammed Tokmak, Veysi̇ Kayri̇, Ramazan Özmen, Kazi̇m Şahi̇n

Turkish Journal of Veterinary & Animal Sciences

Boron (B) is an essential micronutrient involved in hormone activity, energy metabolism, antioxidant defense, bone development, wound healing, and immune function. The present study explores the effects of sodium perborate tetrahydrate (SPT) on nutrient digestibility and the modulation of specific nutrient transporters in the jejunum and ileum of rats. A total of 40 rats were divided into four equal groups: 1) control, 2) SPT 0.5 (0.5 mg B/kg body weight [BW]), 3) SPT 1 (1 mg B/kg BW), and 4) SPT 2 (2 mg B/kg BW), and were fed the respective diets for a period of 4 weeks. The digestibility …

Housing System And Gender Effect On Carcass And Meat Quality Characteristics In Turkish Pekin Ducks, Hasan Önder, Uğur Şen, Mi̇ne Yilmaz, Si̇bel Bozkurt, Eli̇f Ci̇lavdaroğlu, Di̇lek Gökçek, Ahmet Uçar, Kadi̇r Erensoy, Burcu Kurnaz

Turkish Journal of Veterinary & Animal Sciences

Improving meat quality is one of the most important aims for scientists and breeders. This study aimed to evaluate the effects of housing system (indoor vs. free-range) and gender on carcass and meat quality traits in Pekin ducks. The animal material consisted of 20 male and 20 female birds in each housing system. Our results show cold carcass weights of 3174.10 ± 80.65 g and 2672.60 ± 59.63 g for male and female birds in the indoor housing system and 2821.10 ± 50.53 g and 2306.90 ± 43.32 g for male and female birds in the free-range housing system. The …

Effect Of Different Pellet Binders On Palm Kernel On Growth Performance And Nutrient Digestibility In Broiler Chicken, Nuun Marfuah, Burhanudin Sundu, Rusdi Rusdi, Sugiarto Sugiarto

Jurnal Ilmu Ternak Universitas Padjadjaran

Feed plays a paramount role in supporting growth, metabolism, and production performance. Their high price encourages the utilization of inexpensive and alternative feed ingredients. PKM, one such feed ingredient, is produced by palm oil industries. However, there is still a very limited application because of its high crude fiber content, which needs processing technologies like pelletization with binder addition. Based on this background, this experiment has been conducted to study the effect of various types of natural and commercial binders in 15% PKM-based pellets on performance and nutrient digestibility of broilers. The study was done for five weeks using 150 …

The Occupation Of Dance And Its Potential Effects On Trauma, Magan Higgins Gramling

The Open Journal of Occupational Therapy

Trauma is a complex phenomenon. Because of its subjective nature, it can be defined in a variety of ways depending on the health care provider being asked. Though there are various forms of trauma, most definitions are comprised of components that establish its broad understanding of an emotional response to a disturbing incident. Trauma is a subjective experience and can occur in any setting, to any person. How trauma is stored in the body is less subjective though, with most experts understanding it not only lives in the brain, but also in the very cells affecting health and wellness on …

Integrating Oral Thc:Cbd Into Chronic Neuropathic Pain Management In Primary Care: A Two-Patient Observational Case Series, Camryn Butera, Tytianna Robinson, Samantha Temucin, Jade Mcnulty, Ryan Pinto, Maya Rakoczy, Jessica Peskin, Frederick J. Goldstein, Micky Bacchus, Sarah Kizun, Alivia Kurelowech, Alexandra Loverdi, Kruti Patel, Neha Bhardwaj, Tyler Kung, Hiren Walia, Rebecca Han, Alexa Romanella, Christie Okoye

The Journal of Integrated Primary Care

Introduction: Cannabis use among U.S. adults has increased substantially in recent years, and primary care physicians increasingly encounter patients using cannabis for chronic pain management. This case series describes two patients with chronic neuropathic pain participating in an observational study evaluating a dose-controlled oral tetrahydrocannabinol (THC): cannabidiol (CBD) formulation. Methods: Two participants completed a four-week program involving incremental oral administration of a 1:1 THC:CBD formulation. Pain intensity scores, medication use, and health-related quality of life (HRQoL) were assessed before and after the intervention. Results: Both participants reported reductions in pain intensity and decreased reliance on pre-study analgesic …