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Mcv/Q, Medical College Of Virginia Quarterly, Vol. 3 No. 1

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

Sporotrichosis: The Significance Of Variations In Morphology Of Spores In The Tissues, Harry I. Lurie

MCV/Q, Medical College of Virginia Quarterly

The histopathological diagnosis of sporotrichosis is briefly reviewed. The primary lesion consists basically of pseudo-epitheliomatous hyperplasia of the epidermis, intra-epidermal micro-abscesses, a non-specific dermal infiltrate and granulomata composed of central micro-abscess surrounded by a zone of histiocytes and multinucleated giant cells. The significance of the asteroid body is discussed. Evidence is presented to support the view that the development of asteroid bodies and the amount of eosinophilic material in these bodies is related to host resistance and that cigar bodies are found in those cases with little or no resistance and in whom the disease disseminates rapidly and wildly. Avenues …

The Pharmacology Of Newer Diuretics, Albert J. Wasserman

MCV/Q, Medical College of Virginia Quarterly

There are now a number of different classes of diuretics with different pharmacologic effects. Several considerations dictate the choice of diuretic: 1. The responsiveness of the patient is of prime importance. If the patient is not known to be resistant to diuretic therapy, thiazides should be tried first. 2. The danger of alterations of volume and of electrolytes in the specific patient must be considered. Patients receiving digitalis will be subjected to much greater danger by the induction of hypokalemia than patients not receiving cardiac glycosides. 3. The pharmacologic effects of the specific diuretics must be understood for now the …

Iatrogenic Disorders, Robert H. Moser

MCV/Q, Medical College of Virginia Quarterly

The contemporary physician and his patient are riding the crest of the most dramatic expansion of medical capability in history. But the rapid proliferation of medical knowledge has not been entirely benign. Although our reverses have been minor in contrast to our advances, negative effects cannot be ignored. My discussion involves one aspect of this problem--the emergence of what I have called "Diseases of Medical Progress" (Moser, 1964).

The Controversy Over Generic Equivalency Of Drugs, Werner Lowenthal

MCV/Q, Medical College of Virginia Quarterly

The truth about generic equivalency has not yet been determined. The arguments in the generic equivalency controversy are confounded by names, proprietary (trademark, brand name) as opposed to non-proprietary (generic, branded-generic), yet quality of the products is not necessarily related to any name. The efficacy and not the name of the product is important. The crucial question to ask is whether the product is clinically or therapeutically effective, giving reliable and uniform results.

Perspectives And Prospects In The Chemotherapy Of Gastrointestinal Cancer, William Regelson

MCV/Q, Medical College of Virginia Quarterly

5-Flourouracil (5-FU) is the best agent for the treatment of all gastrointestinal cancers but should be used with restraint, since severe toxicity does not guarantee increased response or survival time. Experimental work suggests that glucose enhances cellular uptake of 5-FU. Alkylating agents are definitely useful and occasionally produce long-term responses. Mitomycin C shows activity but is not available. There are reports of responses to methotrexate, vinca alkaloids, and mithramycin, but their place in the management of gastrointestinal cancer is not established. The usefulness of alkylating agents or 5-FU as adjuvants to surgery is not clear, but evidence is accumulating which …

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 3 No. 3

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

Intracellular Co₂ Tension: Practice And Theory, Eugene D. Robin

MCV/Q, Medical College of Virginia Quarterly

I have been asked to discuss methods of measuring intracellular Pco₂ and to discuss the physiology and biochemistry of intracellular CO₂ tensions. Actually, I am in a relatively fortunate position in that my difficulties in discussing the methodology of intracellular Pco₂ measurements are considerably less than those which face my two colleagues. The reason for this becomes apparent if one analyzes the following quantitative relationships. [Includes discussion.]

The Inscription Over The Judge Said: "Reason Is The Life Of The Law.", Ken Sprague, Dee Sprague

Green Revolution

No abstract provided.

Vitamin, Vitamin, Part Iii - Do's And Don'ts For Healthful Living, Dr Ruth Rogers

Green Revolution

No abstract provided.

Letter Explains Vaccination Stand, R Kenneth Sprague, Delores Sprague

Green Revolution

Reprint of letter from School of Living Center residents Kenneth and Delores Sprague to Baltimore County, MD Board of Education explaining why they do not want to vaccinate their children.

Herbs And Your Health - Part Ii, Ben Harris

Green Revolution

No abstract provided.

The Treatment Of Anxiety, John J. Schwab, Nancy H. Mcginnis

MCV/Q, Medical College of Virginia Quarterly

Rational therapy requires accurate diagnosis. When we apply this precept to anxiety a fundamental question arises. Is anxiety an illness in terms of the now berated medical model which holds that an illness has a cause, a natural history, and hopefully a cure? Or is anxiety a basic aspect of the human condition, an innate pattern of response which becomes pathological when stress, induced by physiologic and social forces, is magnified out of proportion to the original stimulus? If the latter is true, then stress and social interactions are the causative factors, the anxiety only a reaction. Logically then, the …

Origins Of Congenital Defects: Epidemiologic Approach, Robert W. Miller

MCV/Q, Medical College of Virginia Quarterly

This presentation consists of several short stories from personal experience to illustrate the complementary nature of epidemiologic and laboratory research in the study of congenital malformations.

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 3 No. 2

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

Pharmacology Of Anti-Anginal Agents, Maurice Mcgregor

MCV/Q, Medical College of Virginia Quarterly

In conclusion I would like to stress that these observations do not constitute direct evidence of the mechanism whereby the nitrates relieve angina pectoris. It is probable that they are capable of causing some reduction of myocardial oxygen consumption. However, there is increasing indirect evidence which suggests that the site of action of these drugs is principally on the large coronary arteries. Their administration may thus relieve coronary spasm, if this ever causes angina, and more importantly will increase collateral flow into ischemic areas of myocardium when collateral channels have become enlarged. Drugs such as dipyridamole which seem to act …

The Physician As Humanist, George T. Harrell

MCV/Q, Medical College of Virginia Quarterly

It is appropriate that this lecture should be given in a building which is devoted to the broader aspects of living and which is located on the campus of an institution which treats bodily ills. This institution began as part of a liberal arts college. This tradition in the state of Virginia started with Mr. Jefferson when the University was established at Charlottesville. He decreed that one of the first chairs should be in medicine, not as preparation for a professional career, but as a discipline which should be understood by all educated men. The faculty at this institution has …

Intracellular Ph Determination By Means Of Ph Glass Microelectrodes, Norman W. Carter

MCV/Q, Medical College of Virginia Quarterly

A number of years ago I decided to attempt to measure the intracellular pH of skeletal muscle by a more direct method than those in current use, that is, by an electrode. I excluded all forms of pH electrodes except the glass electrode and then set up a certain number of characteristics or requirements that this electrode should have. First, the electrode should be insulated in such a manner that only the pH-sensitive portion is in the cell cytoplasm. Second, the reference side of the electrode group should also be within the cell, because the cell has a transmembrane potential; …

The Role Of The Physician In Family Planning, Howard C. Taylor Jr.

MCV/Q, Medical College of Virginia Quarterly

In summary, one can find many reasons for believing that family planning programs should in general be associated with maternity services and that educational efforts should be concentrated during the weeks of pregnancy and the puerperium. During these periods the women of an age and fertility most in need of family planning are easily detectable. They are for obvious reasons interested in the subject and the most susceptible to advice. The staff needed for this work is already partly available among the physicians, nurses, midwives, and social workers connected with maternity services. The system promises to introduce birth control in …

Some Perspectives On Immunosuppressive Drugs, Robert S. Schwartz

MCV/Q, Medical College of Virginia Quarterly

In conclusion, the antimetabolites have proven extremely interesting in the laboratory for the exploration of the mechanism of antibody synthesis and related problems. They have also proven to be extremely useful and interesting materials in the clinic. Whether they are going to replace any other standard forms of therapy, such as the corticosteroids, is, in my view, doubtful. Their use at the moment is experimental and their ultimate place in clinical medicine is by no means settled. They appear to have two important effects in man: 1) Suppression of antibody formation which can be, in many individuals, selective; and 2) …

Diagnostic Ultrasonography, Joseph H. Holmes

MCV/Q, Medical College of Virginia Quarterly

It was the development of radar and sonar during the last World War which made the ultrasonic techniques I am going to talk about possible. Following the War, Dr. K. T. Dussik had the idea that, if one directed ultrasonic waves into the body, one might obtain echoes reflected from tissue surfaces in the same way that the Navy received echo information reflected from the submarine's hull. When he did this, he did get reflected echoes from within the body, and this opened the door for other investigators to demonstrate how this echo information could be made useful in diagnostic …

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 3 No. 4

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

Oxygen Tension: Direct Observations On The Critical Level For The Brain, Frans F. Jӧbsis

MCV/Q, Medical College of Virginia Quarterly

In this lecture I want to address myself to the questions: What is the lowest oxygen tension compatible with adequate function, and what are the factors that set this limit? Much of the background to the material present here has been reviewed extensively in the not too distant past (Jӧbsis '64), and I will take the liberty of letting that article provide most of the detailed justification of my remarks today. [Includes discussion.]

Vol.25 News Releases 1967, American Dental Association

News Releases

This collection includes standard news releases, information kits and other documents distributed for publicity, information, announcements of events, etc. as issued from the ADA. Items included in this collection are archival and any costs, links, contact information, or other figures may be out of date. Please contact the ADA to verify information.

The Utinga Virus: Antigenic Characterization And Serologic Epidemiology, Ihor G. Zachary

Yale Medicine Thesis Digital Library

No abstract provided.

Feeding Urea To Dairy Cows, R A. Bettenay

Journal of the Department of Agriculture, Western Australia, Series 4

IT has been known for some years that the ruminant animal, through the agency of microflora in the rumen, has the ability to use urea as a source of nitrogen, and to convert some of this to protein.

Worms In Sheep. 2. Seasonal Variations In Worm Burdens, R W. Butler

Journal of the Department of Agriculture, Western Australia, Series 4

The first article in this series described the worms which commonly infest sheep in Western Australia and the symptoms caused by heavy infestations.

This article outlines the effects of seasonal changes on worm burdens in sheep.

AS a basis for planning a worm control programme it is essential to have information on the seasonal changes in worm burdens and on the factors which control these.

In this article, the more important of these are considered.

Poison Plants Of Western Australia : The Toxic Species Of The Genera Gastrolobium And Oxylobium. 1. Characteristics Of The Group, T E H Aplin

Journal of the Department of Agriculture, Western Australia, Series 4

THE toxic species of the genera Gastrolobium and Oxylobium are a unique group of poison plants which have caused considerable economic loss to stock-raisers in Western Australia ever since the early days of settlement.

These plants are widely distributed over the agricultural areas of the south-west, and, with the opening up of large tracts of land for stock-raising, the danger is as high as it has even been.

Poison Plants Of Western Australia : The Toxic Species Of The Genera Gastrolobium And Oxylobium : Rock Poison (Gastrobolium Callistachys Meissn.), T E H Aplin

Journal of the Department of Agriculture, Western Australia, Series 4

ROCK POISON, so called because it is commonly found on granitic soils, usually among granite rocks, occurs from the Irwin River, southwards to the Dale River and eastwards to Mount Stirling, south of Kellerberrin.

The Problem Of Pesticide Residues In Animal Products, J Craig

Journal of the Department of Agriculture, Western Australia, Series 4

. . . a summary of the present position concerning pesticide residues in animal products, and recommendations for pest control measures which will avoid residue accumulation.