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The Nature Of Leukocytic Response To Mouse Mammary Tumor Implants In C3h/Hej Mice With And Without Anticoagulation, Melvin Earl Liter

University of the Pacific Theses and Dissertations

Cancer is the second leading cause of death in the United States. The risk of cancer development and subsequent death from the disease increases sharply in the population over 55 years of age(1). Coagulation problems also increase with age and have been implicated in increasing the metastatic spread of cancer. Although cancer treatment has improved constantly it still remains quite toxic and improvement are needed

Mouse mammary tumor is a common form of cancer used for experimental animal study. This investigation was designed to study the nature of leukocytic response to mouse mammary tumor implants in C3H/HeJ mice with and …

The Effect Of Selected Adjuvants On The In Vitro Percutaneous Penetration Of Benzocaine, See-Yan Lam

University of the Pacific Theses and Dissertations

This research project was designed to test whether the in vitro percutaneous penetration of benzocaine through human cadaver skin could be enhanced by dimethyl sulfoxide (DMSO), urea, polyoxyethylene (20) isohexadecyl ether and 1-dodecylazacycloheptan-2-one (Azone) in propylene glycol/water systems. Solubility and partitioning of benzocaine in propylene glycol/water systems was investigated. The adjuvant effects were studied in a 60/40 (V/V) propylene glycol/water co-solvent system. The well known drug penetration enhancer dimethyl sulfoxide did not enhance the penetration of benzocaine at any concentration level of DMSO under the conditions of the experiment. This lack of enhancement effect was probably due to increased solubility …

The Synthesis Of Various Substituted 3-Amino-7-Hydroxy-2,2-Dimethyltetralins And Their Opioid-Related Activities, David Alan Lippman

University of the Pacific Theses and Dissertations

A series of aminotetralones and aminotetralins were synthesized from the common intermediate F, 3-amino-2,2-dimethyl-7-methoxy- 1-tetralone. The final compounds derived from F were simple substituted and/or reduced analogues. The products would allow a progressive structure activity relationship to be drawn based on pharmacological testing.

The common intermediate F was synthesized utilizing a six step procedure starting with p-methoxyphenylacetic acid. The overall yield from the precursor to the F:HC1 was 25%. Compound F was either O-demethylated to form 3-amino-2,2-dimethyl-7-hydroxy-l-tetralone (I) or was dimethylated on the amine and subsequently O-demethylated to yield the 3-dimethylamino-7-hydroxy-2,2-dimethyl-l-tetralone (J). The last major modification was the reduction of …

[3 Cortical Blood Flow And Oxygenation Abstracts], Y. Taguchi, M. Kaminogo, G. Austin

The Dr. George M. Austin Neurology Research Collection

Three presentations stapled together:

The Changes of Cortical Blood Flow and Cortical Oxygen Tension in Focal Ischemia. M. Kaminoga, M.D., Y. Taguchi, G. Austin, M.D. Conference presentation. American College of Surgeon Annual Meeting, January 28, 1984. NOTE 2nd page of this abstract not present in this file. 2nd page is present in Individual presentation posted separately.

Effect of Hypoxia and Hyperoxia of NADH Redox State and Cortical PO₂ in the Rabbit. Y Taguchi, M.D.; M. Kaminogo, M.D.; G. Austin, M.D. Conference Presentation. Southern California Chapter, American College of Surgeons, Santa Barbara, Calif, January 28, 1984.

Autoregulation of Cortical …

Polymorphonuclear Leukocyte Count Within Healing Wound Sites In Non-Diabetic And Diabetic Rat Oral Mucosa, James L. Discipio

Master's Theses

No abstract provided.

The Effect Of Benzodiazepines On The Stress Response To Drug-Induced Hypotension And Surgical Trauma, Gail Elizabeth Gillenwater

Dissertations

No abstract provided.

Analysis Of Forelimb Motor Cortical Projections After Neonatal Hemicerebellectomy In Rats, Daniel L. O'Donoghue

Dissertations

No abstract provided.

Neuroregulation Of The Autophosphorylatable Regulatory Subunit Of Adenosine Cyclic 3':5' Monophosphate-Dependent Protein Kinase Type Ii, Stephen P. Squinto

Dissertations

No abstract provided.

Metastases In Lymph Nodes Of Hamster Buccal Pouch Carcinomas, Kostas Tsiklakis

Master's Theses

No abstract provided.

Parental Presence And Pain Perception In The School-Age Child, Sandra Baran Englert

Master's Theses

No abstract provided.

The Effect Of Body Position And Head Rotation On Intracranial Pressure Readings In Premature Infants With Ladd Monitoring, Martha J. Barthel

Master's Theses

No abstract provided.

A Histological Evaluation Of Experimentally Produced Periapical Pathosis In The Adult Beagle Dog, Ronald Brown

Master's Theses

No abstract provided.

Rate Of Flow And Ph Of Parotid Fluid Stimulated By Various Combinations Of Mechanical And Chemical Elements, Raymond J. Bielinski

Master's Theses

No abstract provided.

Lipogenin, James William. Fitzsimons

Master's Theses

No abstract provided.

The Incidence Of Obesity In Lds College Women: The Effect Of Selected Physical Socio-Environmental Variables On Total Percent Body Fat In Two Populations Of Lds Women, Carrie Tanner Summers

Theses and Dissertations

The purpose of this study was to determine the effect of selected physical socio-environmental variables on total percent body fat. The sample population consisted of single, LDS, white women attending Brigham Young University (BYU) and California State University at Fullerton (CSUF). Significant data as well as trends that appeared were included in this paper.

From the data collected, it was concluded that the sample populations at BYU and CSUF were the same. The incidence of obesity was determined only among individuals attending both universities. The entire sample population mean was 22.19 percent. This percentage did not meet the obesity criteria. …

Evaluation Of Peptide Assimilation In Ehrlich Ascites Tumor Cells, John M. Castellano

Biological Sciences Theses & Dissertations

The dipeptides glycyl-L-(³H)-leucine and L-phenylalanyl-L-(³H)-leucine were synthesized in radioactive form and utilized in the analysis of peptide transport and hydrolysis by Ehrlich ascites tumor cells. The tumor cells were cultured in the abdominal cavity of CF-1 albino mice and harvested into sterile isotonic buffer for all experimental analyses.

The results of this study reveal that the tumor cells rapidly accumulate radiolabel when incubated with the above mentioned peptides, but that the peptide is most probably hydrolyzed extracellularly and free L-(³)-leucine transported. This hypothesis is based on the observations of reduction in accumulation of radiolabel …

Menno-Knight, Winter 1984, Mennonite School Of Nursing

Menno-Knight (1960s-1990s?)

Student newsletter of the Mennonite School/College of Nursing.

The Relationship Of Lean Body Mass To Resting Metabolic Rate, Maryann Butler

Dissertations and Theses @ UNI

Previous investigators have established predictors affecting basal metabolic rate. These include body size, age and sex, surface area, temperature and environment, and exercise. Conflicting data have been reported concerning the expression of basal metabolism in units of square meters of surface area. It was the purpose of this study to observe the relationship of lean body mass (LBM) to resting metabolic rate (RMR) in college-age males of high lean body mass and low lean body mass. A second purpose was to determine the validity of a relatively new method of measuring resting metabolic rate using a whole body calorimeter (WBC). …

A Comparison Of Oxygen Consumption In Light And Heavy Resistance Weight Training Methods In Males, Kean Gerard Richard

Dissertations and Theses @ UNI

Heavy resistance and low resistance weight training methods are commonly used in off season conditioning programs for various sports. Research has indicated that heavy resistance training elicits muscular strength development whereas low resistance training elicits the development of muscular endurance. However, there is very little or no research which has investigated a comparison of oxygen consumption between heavy resistance and low resistance training while keeping work constant.

The purpose of this investigation was to compare the oxygen cost of performing heavy and low resistance weight training methods. Also, a second purpose of the study was to determine the contribution of …

What's Happening: December 21, 1983, Maine Medical Center

What's Happening

No abstract provided.

Pathogenesis Of Hyperparathyroidism, Louis M. Sherwood

Henry Ford Hospital Medical Journal

No abstract provided.

Bone Disease In Uremia, Jack W. Coburn

Henry Ford Hospital Medical Journal

No abstract provided.

Fatty Liver And Metabolism Of Xenobiotics In The Rat, Joyce D. Stone

Theses and Dissertations (ETD)

No abstract provided.

Clinical Applications Of Parathyroid Hormone Assays, John T. Potts Jr.

Henry Ford Hospital Medical Journal

No abstract provided.

Osteoporosis, C. Conrad Johnston

Henry Ford Hospital Medical Journal

No abstract provided.

The Perceptual Effect Of Patients' First Name On The Clinical Judgment Of Psychopathology By Psychotherapists, Dennis G. Cowan

Dissertations

The purpose of this study was to explore the relationship between a patient's first name (desirable versus undesirable) and the clinical judgment of psychopathology by mental health professionals. Specifically, this study examined how a patient's first name affected the diagnosis of maladjustment.

A total of 266 mental health professionals viewed a standardized video taped interview with a patient. Through the analysis of two surveys, the following first names were randomly presented with the viewed patient: Christopher, David, Mortimer and Junior. It was found, at the .00001 level of probability, that when the patient possessed the less desirable first name of …

A Study Of The Environmental Aspects Of Schistosomiasis In Libya, Abubaker I. Swehli

Dissertations

Schistosomiasis is a serious disease in humans. Two species of schistosome, Schistosoma mansoni and Schistosoma haematobium, organisms that cause the disease, parasitize humans in Libya. Schistosomes require aquatic snails in their life cycle. The purpose of this study was to investigate the environmental and the host relationships of the disease in the three regions of Libya where the disease is found. These relationships include:

1) Analyses of the physical-chemical characteristics of the aquatic habitat.

2) Collection of snails to determine: a) the kind of snail species and th e ir abundance; and b) the cercarial infestation rates.

3) Infection rates …

Distribution And Proportion Of Immunoreactive Neuron Specific Enoclase Containing Cells In The Rat Pineal Gland, Alfonso Miranda C.

Loma Linda University Electronic Theses, Dissertations & Projects

The distribution and proportion of cytoplasm containing immunoreactive neuron specific enolase (NSE) in the rat pineal have been investigated. Step serial sections of the pineal glands of 7 male Sprague-Dawley rats were stained for NSE using an indirect immunoperoxidase method. The volumes of the pineals and of the regions containing reactive cells were derived from the distance between sections and the sum of the corresponding sectional areas of camera lucida drawings. The proportion of the NSE areas actually consisting of NSE reactive cytoplasm was measured using an image array processor.

Cytoplasm reactive for NSE was consistently localized to the posterior …

A Histopathological Assessment Of The Effects Of Streptozotocin-Induced Diabetes On The Ears Of Chinese Hamsters, Karen Ailsworth

Masters Theses

Research has produced evidence associating progressive, bilateral, sensorineural hearing loss with diabetes mellitus in human and animal subjects. The microangiopathy which is presumably the cause of hearing loss appears similar to the microangiopathy leading to retinal and renal atrophy.

In the present study the temporal bones of six streptozotocininduced diabetic Chinese hamsters and six nondiabetic Chinese hamsters were histologically processed. Sections stained with hematoxylin and eosin were assessed for total auditory and vestibular otopathology and revealed no statistically significant differences between the two groups. Sections stained with periodic acid-Schiff's were evaluated for vascular basement membrane changes and revealed no statistically …

The Tixicity Of Nitoxynil In Cattle, Vichitr Sukhanpesna

The Thai Journal of Veterinary Medicine

The toxicity of nitroxynil administered subcutaneously was determined in Thai native and crossbred calves and yearling cattle. Maximum tolerated dosage was 50 milligrams per kilogram in calves and yearling cattle. Lethal dosage were 55 milligrams per kilogram in calves and yearling cattle. The toxic doses caused the animals death in 24 to 28 hours with clinical signs. At the dose rate of 10 milligrams per kilogram, nitroxynil had no effect on fertility, embryoes or foetuses. The drug could be administered repeatedly at 1 month interval to the pregnant cows up to 8 months of gestation period without affecting reproductive performance.