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Vocal Recognition Of Pups By Mother Mexican Free-Tailed Bats, Tadarida Brasiliensis Mexicana, Jonathan P. Balcombe

Sentience Collection

The ability of Mexican free-tailed bat mothers and pups to recognize vocalizations of their presumptive kin (pup isolation calls and mother echolocation calls, respectively) was tested using playbacks of recorded calls. Captive individuals were presented with calls of two bats, one presumptive kin and the other a stranger, from opposite sides of a circular wire arena. Response was determined by amount of time spent on each side of the arena, time spent in contact with a cloth bat model in front of each speaker, and number of separate contacts with each model. For the latter two measures, mothers showed a …

Update - May 1990, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- James Walters wins NEH Grant
-- Fraud in Modern Medicine
-- Roy Branson serves as guest professor of medical ethics
-- Cambridge publishes Michael Pearson's study of Adventist ethics

[ RU486: Blessing or Curse? ]
-- Medical Aspects of RU486
-- The Curse of RU486: The Death Pill
-- RU486: A Very Mixed Blessing

-- Robert Wirth sparks aging project

What's Happening: April 25, 1990, Maine Medical Center

What's Happening

No abstract provided.

Long-Term Effects Of Early Social Isolation In Macaca Mulatta: Changes In Dopamine Receptor Function Following Apomorphine Challenge, Mark H. Lewis, John P. Gluck, Tom L. Beauchamp, Michael F. Keresztury, Richard B. Mailman

Experimentation Collection

The hypothesis that early social isolation results in long-term alterations in dopamine receptor sensitivity was tested using older adult rhesus monkeys. Isolated and control monkeys were challenged with apomorphine (0.1 and 0.3 mg/kg), and the drug effects on spontaneous blink rate, stereotyped behavior, and self-injurious behavior were quantified using observational measures. Monoamine metabolites were quantified from cisternal CSF by HPLC-EC, prior to pharmacological challenge. Isolated and control monkeys did not differ in CSF concentrations of HVA, 5-HIAA, or MHPG. At the higher dose, apomorphine significantly increased the rate of blinking, the occurrence of whole-body stereotypies, and the intensity of stereotyped …

Bulletin - April, 1990, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A six page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.

Morphological And Physiological Examination Of A Demyelinating And Remyelinating Lesion, Paul Anson Felts

Theses and Dissertations in Biomedical Sciences

Multiple sclerosis causes demyelination of central nerve fibers, and it is this pathology which results in most of the symptoms of the disease. The repair of the fibers by remyelination has been advanced as a potential symptomatic therapy, but at present the conduction properties of remyelinated central fibers are not well understood. In this study the conduction properties of Schwannian or oligodendrocyte remyelinated central nerve fibers have been determined. In addition, the status of the blood-brain barrier has been examined in lesions characterized by Schwann cell remyelination. These lesions chronically lack astrocytes, a cell believed to be involved in the …

C. Paul Hodgkinson, Md, Dorothy Porter

Henry Ford Hospital Medical Journal

No abstract provided.

Cocaine-Induced Hepatonephrotoxicity: A Case Report, Guillermo P. Gubbins, Rhett M. Schiffman, Ravindra S. Alapati, Surinder K. Batra

Henry Ford Hospital Medical Journal

Hepatotoxicity due to cocaine has been well described in animal models. There are few reports on cocaine-induced hepatic injury in humans; however, its link to rhabdomyolysis and renal failure is better known. We report a case of reversible acute hepatonephrotoxicity associated with recreational cocaine use. The proposed mechanisms responsible for its hepatic and renal toxicity are reviewed.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Home Safety-The Challenge To Public Health, Ray Ranson

The Journal of Sociology & Social Welfare

Home accidents are now a leading cause of death and injury particularly in young children and the elderly. For example, 3.1 million accidents occur in the home every year in the United Kingdom with no signs of diminishment. More effective systems of accident recording, monitoring, investigation, intercollaboration and education are urgently needed to redress this epidemic. More attention needs to be given to preventive safety design in architect training and adoption of home safety design standards and legislation. The major threat to public health which home accidents represent must not go unchallenged.

Analysis Of The Transcriptional Promoter Which Regulates The Latency-Related Transcript Of Bovine Herpesvirus 1, Clinton J. Jones, G. Delhon, A. Bratanich, G. Kutish, D. Rock

School of Veterinary and Biomedical Sciences: Faculty Publications

As a transcriptional promoter in primary cultures of sensory ganglionic neurons, DNA sequences near the 5' terminus of the latency-related (LR) gene of bovine herpesvirus 1 were at least 10 times more efficient than the simian virus 40 early promoter-enhancer. In contrast, as a promoter in bovine, rodent, or monkey cells, the LR promoter was approximately six times less efficient than the simian virus 40 early promoter-enhancer. The LR promoter had strict orientation preferences in neurons and all other mammalian cell lines tested. Removal of a 146-base-pair XhoI fragment from the LR promoter resulted in stimulation of LR promoter …

Plasma Native And Peptidase-Derivable Met-Enkephalin Responses To Restraint Stress In Rats. Adaptation To Repeated Restraint, K. Pierzchala, G. R. Van Loon

Internal Medicine Faculty Publications

Met-enkephalin and related proenkephalin A-derived peptides circulate in plasma at picomolar concentration as free, native pentapeptide and at nanomolar concentration in cryptic forms. We have optimized conditions for measurement of immunoreactive Met-enkephalin in plasma and for generation by trypsin and carboxypeptidase B of much greater amounts of total peptidase-derivable Met-enkephalin in plasma of rats, dogs, and humans. Free Met-enkephalin (11 pM) is constituted by native pentapeptide and its sulfoxide. Characterization of plasma total Met-enkephalin derived by peptidic hydrolysis revealed a small amount (38 pM) of Met-enkephalin associated with peptides of molecular mass less than 30,000 D, and probably derived from …

Identification And Characterization Of The Herpes Simplex Virus Type 2 Gene Encoding The Essential Capsid Protein Icp32/Vp19c, S P Yei, S I Chowdhury, B M Bhat, A J Conley, W S Wold, W Batterson

Faculty, Staff and Student Publications

We describe the characterization of the herpes simplex virus type 2 (HSV-2) gene encoding infected cell protein 32 (ICP32) and virion protein 19c (VP19c). We also demonstrate that the HSV-1 UL38/ORF.553 open reading frame (ORF), which has been shown to specify a viral protein essential for capsid formation (B. Pertuiset, M. Boccara, J. Cebrian, N. Berthelot, S. Chousterman, F. Puvian-Dutilleul, J. Sisman, and P. Sheldrick, J. Virol. 63: 2169-2179, 1989), must encode the cognate HSV type 1 (HSV-1) ICP32/VP19c protein. The region of the HSV-2 genome deduced to contain the gene specifying ICP32/VP19c was isolated and subcloned, and the nucleotide …

Murine Gamma Interferon Fails To Inhibit Toxoplasma Gondii Growth In Murine Fibroblasts., Joseph D. Schwartzman, Steven L. Gonias, E R. Pfefferkorn

Dartmouth Scholarship

Although treatment of human macrophages or fibroblasts with human gamma interferon results in the inhibition of intracellular Toxoplasma gondii, murine gamma interferon stimulated only murine macrophages, not murine fibroblasts, to inhibit T. gondii. This species difference may be important in understanding the control of acute and chronic toxoplasmosis.

The Role Of Calcium Ions In Toxic Cell Injury., John L. Farber

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Calcium ions have been increasingly implicated as a mediator of the mechanisms generating lethal cell injury under a variety of pathologic circumstances. An overview of the various roles suggested for such alterations in cellular calcium homeostasis is presented. The central role of plasma membrane damage in the genesis of irreversible cell injury is used to divide the postulated roles for calcium ions into two major mechanisms. On the one hand, calcium ions have been proposed as mediators of the functional consequences of plasma membrane injury. An influx of extracellular calcium ions across a damaged permeability barrier and down a steep …

What's Happening: February 28, 1990, Maine Medical Center

What's Happening

No abstract provided.

Susceptibility Of Hepatic Microcirculation To Reperfusion Injury: A Comparison Of Adult And Suckling Rats., Alan M. Yahanda Md, Facs, C N Paidas, M G Clemens

Other Specialties

Primary graft failure and vascular thromboses are frequent complications of liver transplantation, yet the mechanisms responsible remain unclear. Previous work from our laboratory has shown that hepatic reperfusion injury results in damage at the microvessel level. The present study was performed to determine whether an increased susceptibility of immature animals to microvascular injury during reperfusion might be a contributing factor in these complications. Suckling (35 to 50 g) or adult (250 to 400 g) rats were subjected to 30 or 60 minutes of hepatic ischemia to the left and median lobes followed by 90 minutes of reperfusion. Control animals were …

Ciliary Microtubule Capping Structures Contain A Mammalian Kinetochore Antigen, J. M. Miller, W. Wang, Ron Balczon, W. L. Dentler

University Faculty and Staff Publications

Structures that cap the plus ends of microtubules may be involved in the regulation of their assembly and disassembly. Growing and disassembling microtubules in the mitotic apparatus are capped by kinetochores and ciliary and flagellar microtubules are capped by the central microtubule cap and distal filaments. To compare the ciliary caps with kinetochores, isolated Tetrahymena cilia were stained with CREST (Calcinosis/phenomenon esophageal dysmotility, sclerodactyly, telangiectasia) antisera known to stain kinetochores. Immunofluorescence microscopy revealed that a CREST antiserum stained the distal tips of cilia that contained capping structures but did not stain axonemes that lacked capping structures. Both Coomassie blue-stained gels …

The Incidence Of Lupinosis In Sheep Grazing Phomopsis-Resistant Lupin Stubbles, Peter Morcombe, Jeremy Allen

Journal of the Department of Agriculture, Western Australia, Series 4

Lupinosis is one of the major diseases of grazing livestock in Western Australia. It occurs when animals graze lupin stubble containing toxins produced by the fungus Phomopsis leptostromiformis. The Department of Agriculture has recently released new cultivars of Lupinus angustifolius which are more resistant to colonization by Phomopsis, and therefore develop less toxicity, than those previously available (Cowling et al. 1988). The new cultivars - Gungurru and Yorrel - are called Phomopsis-resistant, however their resistance is only moderate. The old cultivars are referred to as Phomopsis-susceptible.

Cyclosporine-Induced Sympathetic Activation And Hypertension After Heart-Transplantation, Urs Scherrer, Susan F. Vissing, Barbara J. Morgan, Julia A. Rollins, Richard S. A. Tindall, Steves Ring, Peter Hanson, Pramod K. Mohanty, Ronald G. Victor

Internal Medicine Publications

BACKGROUND.

Hypertension is a frequent complication of cyclosporine-induced immunosuppression, but the underlying mechanism is unknown. In anesthetized animals, the administration of cyclosporine increases sympathetic-nerve discharge, which may contribute to hypertension.

METHODS.

To determine whether cyclosporine-induced hypertension is accompanied by sustained sympathetic neural activation in patients, we recorded sympathetic action potentials using intraneural microelectrodes (in the peroneal nerve) in heart-transplant recipients receiving azathioprine and prednisone alone (n = 5) or in combination with cyclosporine (n = 14). We performed the same studies in eight patients with myasthenia gravis who were receiving cyclosporine and eight who were not, in five patients with …

Reference Groups And Ritualistic Behavior: A Cultural Perspective On Addiction, Doris Jean Smith

Theses Digitization Project

No abstract provided.

Priming Effects In Perceptual Classification, John H. Flowers

Department of Psychology: Faculty Publications

Priming stimuli that spatially flank a fixated target stimulus may cause either facilitation or interference with target classification, depending on experimental context. Two experiments demonstrated distinct effects of response compatibility and semantic congruity between flankers and target. Response competition occurred when targets were flanked by context stimuli associated with the opposite response, but this effect diminished when the target was delayed relative to the flankers. Facilitative priming by response-compatible flankers, in contrast, required prior exposure of the flankers, and was strongly influenced by the semantic congruity of flankers and targets. These differing time courses suggest that perceptual priming encompasses a …

Understanding Dogs Through Kinesthetic Empathy, Social Construction, And History, Kenneth J. Shapiro

Sentience Collection

The term, "come into animal presence," she takes from the title of a Denise Levertov poem. The poem, which reads, in part, "What joy when the insouciant armadillo glances at us and doesn't quicken his trotting across the track into the palm bush. What is this joy?" This joy is the possibility of our being in the presence of animals for "(t)he armadillo has some intention to pursue in the palm forest." This joy, to which I invite you here, consists in dwelling in that presence, in inhabiting that intention, that armored but guileless world of the armadillo. I will …

Alternatives To And Reduction Of Animal Use In Biomedical Research, Education And Testing, John M. Frazier, Alan M. Goldberg

Experimentation Collection

Biomedical endeavours can be divided into three major categories: research, education, and testing. Within the context of each of these categories, activities involving whole animals have made major contributions and will continue to do so in the future. However, with technological developments in the areas of biotechnology and computers, new methods are already reducing the use of whole animals in certain areas. This article discusses the general tissues of alternatives and then focuses on the development of new approaches to toxicity testing.

Chemical Immobilization Of Red Foxes (Vulpes Vulpes), Terry J. Kreeger, Ulysses S. Seal, John R. Tester

Zoonotics and Wildlife Disease: Publications

Red foxes (Vulpes vulpes) were immobilized with one of the following drug combinations: ketamine/xylazine (n = 22), ketamine/ promazine (n = 35), ketamine/midazolam (n = 13), or tiletamine/zolazepam (n = 22). Foxes given ketamine/xylazine had the shortest induction and longest recovery times relative to other drug combinations, whereas foxes given ketamine/midazolam had the longest induction times. Recommended doses for the various combinations are given. Foxes given ketamine/xylazine were given either 0.1, 0.2, 0.4 mg/kg yohimbine, or saline 40 mm after anesthetic induction. Administration of yohimbine significantly shortened arousal and recovery times relative to control values (P < 0.001).

Determining Matrilines By Antibody Response To Exotic Antigens, Gregory E. Glass, James E. Childs, James W. Leduc, Sandra D. Cassard, Albert D. Donnenberg

Zoonotics and Wildlife Disease: Publications

The antibody responses of female Microtuspennsylvanicus inoculated with a series of antigens not normally encountered under field conditions were examined, and the kinetics of maternally acquired antibody loss in their offspring were determined. The initial antibody response in adults was rapid, peaking in 4-9 weeks, and long-lasting, with a half life of 4-5 months. Antibody levels in females were unaffected by parity, and more than one antigen could be given without affecting circulating-antibody titers. Antibody titers could be enhanced with additional inoculations. Maternal antibody in offspring increased until weaning at 3 weeks then declined exponentially. Minimal detectable titers were reached …

Binder 208, Life Histories E-G [Trematoda Taxon Notebooks], Harold W. Manter Laboratory Of Parasitology

Trematoda Taxon Notebooks

Abstract

Binder 208, Life histories E-G [Trematoda Taxon Notebooks].

Harold W. Manter Laboratory of Parasitology, University of Nebraska State Museum, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.

Created between 1960 and 1990.

Binder 207, Life Histories C-D [Trematoda Taxon Notebooks], Harold W. Manter Laboratory Of Parasitology

Trematoda Taxon Notebooks

Abstract

Binder 207, Life histories C-D [Trematoda Taxon Notebooks].

Harold W. Manter Laboratory of Parasitology, University of Nebraska State Museum, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.

Created between 1960 and 1990.

Binder 014, Aspidogastridae [Trematoda Taxon Notebooks], Harold W. Manter Laboratory Of Parasitology

Trematoda Taxon Notebooks

Abstract

Binder 014, Aspidogastridae [Trematoda Taxon Notebooks].

Harold W. Manter Laboratory of Parasitology, University of Nebraska State Museum, University of Nebraska-Lincoln.

Created between 1960 and 1990.

Binder 018, Brachylaemidae [Trematoda Taxon Notebooks], Harold W. Manter Laboratory Of Parasitology

Trematoda Taxon Notebooks

Binder 018, Brachylaemidae [Trematoda Taxon Notebooks].

Harold W. Manter Laboratory of Parasitology, University of Nebraska State Museum, University of Nebraska-Lincoln.

Created between 1960 and 1990.