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The Efficacy Of A Porcine Plasma Protein Derived Colostrum Supplement On The Surviral And Growth Retes Of Piglets, Athipoo Nuntaprasert, Vivat Chavananikul, Prachak Poomvises

The Thai Journal of Veterinary Medicine

Five hundred seventy nine piglets from four standard breeder farms in four provinces of Thailand, weighing between below 1.0 kg and between 1.0-1.2 kg, were used in this trial. The animals were divided into two groups. The first group performed as control (n=239). In the second group (n=340), each piglet was given two 5 ml doses of porcine plasma protein derived colostrum supplement at the first and third day of the pig life. The results indicated that the survival and growth rates at 21 days of age in the treated group were significantly improved compared to the control group at …

Update - March 1997, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- James Walters publishes book on Personhood
-- Prayer and Health Care: An "Altared" Responsibility
-- Conference Report on "Bioethics and Human Destiny: Jewish and Christian Perspectives"

Transgenic Mice Which Overexpress Nerve Growth Factor, Kathryn M. Albers, Brian M. Davis

Neuroscience Faculty Patents

Transgenic mice that express increased levels of nerve growth factor (NGF) in the epidermis and other stratified, keratinized epithelium. The nerve growth factor expressing transgenic mice are useful in the study of neurodegenerative disorders of the brain such as Parkinson's syndrome and Alzheimer's disease and for testing for drug candidates for the treatment of these diseases.

Prenatal Cocaine Exposure And Mother–Infant Interaction: Implications For Occupational Therapy Intervention, Heather Miller-Kuhaneck

Occupational Therapy Faculty Publications

The literature from multiple disciplines on in utero cocaine exposure and mother–infant interaction and attachment was examined for possible relationships and implications for occupational therapists. Maternal cocaine use and neurobehavioral deficits in neonates prenatally exposed to cocaine may result in interactional difficulties between mother and infant. Knowledge of child development, sensory regulation, and infant cues will enable therapists to assist the mother in creating positive interactive experiences between herself and her child.

Menno-Knight, February 1997, Mennonite College Of Nursing

Menno-Knight (1960s-1990s?)

Student newsletter of the Mennonite School/College of Nursing.

The Role Of Zinc In Health And Disease: Relevance To Child Health In Developing Countries, Z A. Bhutta

Department of Paediatrics and Child Health

No abstract provided.

Loss Of Dcc Expression And Glioma Progression., M Reyes-Mugica, K Rieger-Christ, H Ohgaki, B C Ekstrand, M Helie, G Kleinman, Alan M. Yahanda Md, Facs, E R Fearon, P Kleihues, M A Reale

PCI Publications and Projects

The deleted in colorectal cancer (DCC) gene, a candidate tumor suppressor gene on chromosome 18q21, encodes a neural cell adhesion molecule family protein that is most highly expressed in the nervous system. To address the hypothesis that DCC may play a role in glioma development and/or progression, we examined DCC expression by immunohistochemistry in 57 resected human astrocytic tumors. Overall, low-grade astrocytomas were predominantly DCC positive (15 of 16, or 94%), whereas high-grade tumors significantly less often expressed the DCC protein (27 of 41, or 66%; P = 0.03). We were able to directly assess the relationship between DCC expression …

Safety Guidelines For Occupational Hazards To The Reproductive System, Laverne Raquel Ogieste

Theses

Most workers are unaware of the hazards to the reproductive system that surround them in the workplace, and therefore, few if any precautions are taken to avoid unnecessary exposures. In this research, safety guidelines were developed in order to eliminate such dangers from occurring or reoccurring.

These guidelines were developed by reviewing case studies of occupational hazards to the reproductive system, including federal laws and regulations related to safety within the workplace. The following forms were also developed in order to formulate suitable safety guidelines for occupational hazards to the reproductive system. They are: an occupational reproductive survey, a reproductive …

Rebuilding Little Lives : Using Play Therapy With Traumatized Children, Denise E. Maas

Graduate Research Papers

In this paper, the author will attempt to assist therapists with their work with traumatized children using play therapy. The discussion includes signs and symptoms that a traumatized child may exhibit. In addition, the paper will contain selected therapeutic powers of play and how they can aid in the treatment of traumatized children. The case examples provided throughout this paper are actual experiences taken from the author's clinical practice in a hospice setting.

An Immunomodulating Mycotoxin Interferes With The Development Of Autoimmune Diabetes In Diabetes-Prone Bb/Wor Rats, Honggang Liu

Theses, Dissertations and Capstones

Various fungal products have immunomodulating activity and some have been studied regarding prevention of transplantation rejection. Prior to this investigation, the mycotoxin, gliotoxin (GT), has never been investigated as an immunotherapeutic drug for autoimmune disease. GT is a fungal secondary metabolite and a member of the epipolythiodioxopiperazine (ETP) family which has been shown to inhibit phagocytosis, induction of cytolytic T cells and the proliferation of T cells following mitogen stimulation. GT also induces in vitro apoptosis in certain immune cell types. More importantly, GT exhibits selective activity towards cells of hemopoietic origin.

Autoimmune diseases are disorders caused by immune responses …

Articulations 1997, Som School Of Osteopathic Medicine, Umdnj University Of Medicine And Dentistry Of Nj

Yearbooks

University of Medicine and Dentistry of New Jersey (UMDNJ) School of Osteopathic Medicine yearbook for the class of 1997. 114 pages.

Contents: Poem: "Janet and Tony" p. 1, UMDNJ-SOM Campus p. 2, University Affiliated Medical Centers p. 3, Dean's Message p. 4, Administration p. 5, Faculty p. 6, Candids p. 7, Class of 1997 p. 34, Convocation and Graduation p. 96, Class of 1997 Directory p. 102, Yearbook Staff p. 102, Osteopathic Oath p. 104.

Aspartate 19 And Glutamate 121 Are Critical For Transport Function Of The Myo-Inositol/H+ Symporter From Leishmania Donovani, Andreas Seyfang, Michael Kavanaugh, Scott M. Landfear

Biomedical and Pharmaceutical Sciences Faculty Publications

The protozoan flagellate Leishmania donovani has an active myo-inositol/proton symporter (MIT), which is driven by a proton gradient across the parasite membrane. We have used site-directed mutagenesis in combination with functional expression of transporter mutants in Xenopusoocytes and overexpression in Leishmania transfectants to investigate the significance of acidic transmembrane residues for proton relay and inositol transport. MIT has only three charged amino acids within predicted transmembrane domains. Two of these residues, Asp¹⁹ (TM1) and Glu¹²¹ (TM4), appeared to be critical for transport function of MIT, with a reduction of inositol transport to about 2% of wild-type …

Exercise During Pregnancy, Sue Merkel

Physical Therapy Scholarly Projects

Physical fitness and sports participation has increased in popularity over the years. This raises concerns as to whether exercising while pregnant is beneficial or harmful to the mother and her unborn child. Research has determined the maternal and fetal responses during various forms of exercise. This research has been used to help establish guidelines and recommendations for pregnant women. However, there continues to be controversy as to the exercise guidelines pregnant females need to follow. Women experience physical changes throughout their pregnancy which can lead to low back pain, abdominal or pelvic floor dysfunctions. These complications can be prevented or …

Harry F. Harlow And Animal Research: Reflection On The Ethical Paradox, John P. Gluck

Experimentation Collection

With respect to the ethical debate about the treatment of animals in biomedical and behavioral research, Harry F. Harlow represents a paradox. On the one hand, his work on monkey cognition and social development fostered a view of the animals as having rich subjective lives filled with intention and emotion. On the other, he has been criticized for the conduct of research that seemed to ignore the ethical implications of his own discoveries. The basis of this contradiction is discussed and propositions for current research practice are presented.

Effects Of Mdl-72222 On Cocaine- And Morphine-Induced Conditioned Place Preference In Preweanling Rats, Bonnie Sue Butterfield

Theses Digitization Project

No abstract provided.

The Effect Of Silica Inhibition Of Macrophage On Renal Allograft Rejection, Carman Giacomantonio

Data and Test Instruments

Kidney failure, one of the most serious complications of diabetes is routinely managed by kidney allograft transplantation. Research into the etiology of diabetes has revealed that macrophages are primarily responsible for the β-islet cell destruction in diabetes and that depletion of macrophages using intraperitoneal (i.p.) silica, which is selectively toxic to macrophages, prevents this. Macrophages accounts for approximately 50% of the graft infiltrating cells (GIC) observed in an acutely rejecting kidney, a process phenotypically very similar to a delayed type hypersensitivity (DTH) reaction. Macrophages are known to be essential for DTH reactions. Their exact role has never been elucidated in …

Prp Genotypes And Experimental Scrapie In Orally Inoculated Suffolk Sheep In The United States, Katherine I. O'Rourke, G. R. Holyoak, W. W. Clark, J. R. Mickelson, S. Wang, R. P. Melco, T. E. Besser, W. C. Foote

Zoonotics and Wildlife Disease: Publications

One-hundred and three United States Suffolk sheep were inoculated orally with a scrapie agent preparation and monitored for clinical disease and histopathological lesions characteristic of scrapie. A retrospective study of the polymorphisms at codon 171 of the prion protein (PrP) gene was performed on these sheep. All 63 sheep that developed scrapie during the observation period were homozygous for the glutamine 171 (171-QQ) PrP allele. Twelve 171-QQ sheep failed to develop disease. All 5 sheep homozygous for arginine (171-RR) and all 23 heterozygous (171-QR) sheep remained free of scrapie.

Spongiform Encephalopathy In Free-Ranging Mule Deer (Odocoileus Hemionus), White-Tailed Deer (Odocoileus Virginianus) And Rocky Mountain Elk (Cervus Elaphus Nelsoni) In Northcentral Colorado, T. R. Spraker, M. W. Miller, E. S. Williams, D. M. Getzy, W. J. Adrian, G. G. Schoonveid, R. A. Spowart, Katherine I. O'Rourke, J. M. Miller, P. A. Merz

Zoonotics and Wildlife Disease: Publications

Between March 1981 and June 1995, a neurological disease characterized histologically by spongiform encephalopathy was diagnosed in 49 free-ranging cervids from northcentral Colorado (USA). Mule deer (Odocoileus hemionus) were the primary species affected and accounted for 41(84%) of the 49 cases, but six Rocky Mountain elk (Cereus elaphus nelsoni) and two white-tailed deer (Odocoileus virginianus) were also affected. Clinical signs included emaciation, excessive salivation, behavioral changes, ataxia, and weakness. Emaciation with total loss of subcutaneous and abdominal adipose tissue and serous atrophy of remaining fat depots were the only consistent gross findings. Spongiform encephalopathy …

Childhood Physical Or Sexual Abuse As A Possible Indicator Of Subsequent Adult Anxiety Disorders, Lynn Merry Cornwell

Graduate Research Papers

In recent years, there has been a growing acceptance that childhood physical and sexual abuse lead to higher rates of psychiatric morbidity in adulthood. Childhood abuse experiences have been reported to be highly prevalent among patients with anxiety disorders. Similarly, childhood incest victims have been found to suffer from a significantly higher rate of anxiety disorders in adulthood especially agoraphobia, than a non-victimized, matched comparison group. Epidemiology studies also support a relationship between childhood abuse and the subsequent development of anxiety disorders. Two separate community surveys found that childhood sexual victimization predicted the later onset of agoraphobia, obsessive-compulsive disorder, and …

Cancer Mortality In Workers Exposed To Phenoxy Herbicides, Chlorophenols, And Dioxins, Manolis Kogevinas, Heiko Becher, Trevor Benn, Pier Alberto Bertazzi, Paolo Boffetta, H. Bas Bueno-De-No-De-, David Coggon, Didier Colin, Dieter Flesch-Janys, Marilyn Fingerhut, Lois Green, Timo Kauppinen, Margareta Littorin, Elsebeth Lynge, John D. Mathews, Manfred Neuberger, Neil Pearce, Rodolfo Saracci

United States Public Health Resources

The authors examined cancer mortality in a historical cohort study of 21,863 male and female workers in 36 cohorts exposed to phenoxy herbicides, chlorophenols, and dioxins in 12 countries. Subjects in this updated and expanded multinational study coordinated by the International Agency for Research on Cancer were followed from 1939 to 1992. Exposure was reconstructed using job records, company exposure questionnaires, and serum and adipose tissue dbxin levels. Among workers exposed to phenoxy herbicides contaminated with 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD) or higher chlorinated dioxins, mortality from soft-tissue sarcoma (6 deaths; standardized mortality ratio (SMR) = 2.03, 95% confidence interval (CI) 0.75-4.43) …

Acyclic Phosphonomethylether Nucleosideinhibitors Of Respiratory Viruses, Dale L. Barnard, N. Bischofberger, C. U. Kim, J. H. Huffman, R. W. Sidwell, J. P. Dougherty, W. Lew, M. A. Williams, W. Yang

Animal, Dairy, and Veterinary Science Faculty Publications

A series of acyclic phosphonomethylether nucleosides were synthesized and then evaluated for inhibitory activity against respiratory viruses of clinical significance using CPE inhibition, neutral red uptake and virus yield reduction assays. Of the 20 compounds synthesized, none significantly inhibited influenza A or B viruses or respiratory syncytial virus strains A2, Long or 18537; the selective indices (SI) were less than 10. A new compound, GS-2128 (2R, 5R-9-[2,5-dihydro-5-(phosphonomethoxy)-2-furanyl]adenine; D4API), selectively inhibited adenovirus 5 (SI>10) as did GS-0577 (9-(3-hydroxy-2-phosphonylmethoxypropyl)-adenine; HPMPA) and GS-0504 [(S)-1-[3-hydroxy-2-(phosphonylmethoxypropyl)]-cytosine; HPMPC]. The 50% effective concentrations (EC50) ranged from 8-100 μg mL-1 and 50% cell inhibitory concentrations (CC50) from …

Regulation Of The Ncx1 Gene In The Normal And Hypertrophied Myocardium, Kimberly Victoria Barnes

MUSC Theses and Dissertations

The sodium-calcium exchanger (NCX1) plays a major role in calcium efflux, and therefore, in calcium homeostasis in the heart. The exchanger mRNA and protein is rapidly upregulated within one hour of pressure overload. In this work, the exchanger has been shown to be upregulated by persistent pressure overload for at least one to two weeks. The 5' end of the NCX1 gene has been characterized in order to examine transcriptional regulation of the cardiac promoter. Four feline NCX1 isoforms of the 5' untranslated region have been cloned: one from brain (Br1), one from kidney (K1), and two from heart (H1 …

Environmental Risk Factors And Cancer In The Charleston Heart Study, Vicki Bishop Benard

MUSC Theses and Dissertations

Existing research suggests that a variety of environmental factors play an important role in cancer mortality. The association between some of these factors and cancer mortality was examined using data from the Charleston Heart Study, a thirty-five year prospective cohort. Baseline measurements for tobacco use, place of residence, occupation, education, water supply and physical activity were made in 1960/63 on 2,283 participants. The vital status of the cohort was ascertained through 1994, and the underlying cause of death as determined by the nosologist was used to define cancer mortality. There were 294 cancer deaths identified over the 35-year period. Statistical …

Dexamethasone Decreases Cell-Cell Adhesion In The 235-1 Pituitary Tumor Cell Line, Phillip Richard Spangler

Theses, Dissertations and Capstones

Physical contacts between cells are known to influence a broad range of biological activities. Investigations into the regulation of prolactin gene expression have shown that cell behavior within the pituitary may also be affected by adhesive contacts. To better understand the mechanisms that regulate cell-cell adhesive contacts in these endocrine cells, we developed a procedure that quantitatively assays homotypic aggregation in the rat pituitary tumor cell line, 235-1. We observed that treatment of 235-1 cells with dexamethasone (Dex), a synthetic glucocorticoid, not only reduces prolactin production but also decreases the reformation of cell-cell contacts. In two independent experiments, control cells …

Indicator Bacteria Concentrations Of Two Northwest Arkansas Streams In Relation To Flow And Season, Dwayne R. Edwards, Mark S. Coyne, Tommy C. Daniel, P. F. Vendrell, J. F. Murdoch, P. A. Moore Jr.

Biosystems and Agricultural Engineering Faculty Publications

Concentrations of indicator bacteria such as fecal coliform (FC) and fecal streptococcus (FS) are often used to assess the suitability of waters for their intended use(s) and to allocate resources for water quality improvement measures. There is evidence, however, that concentrations of FC and FS can be influenced by variables such as season and flow rate during sampling, which could lead to biased results. The objective of this study was to assess the impacts of season and flow rate on concentrations of FC and FS. Fecal indicator bacteria concentrations were measured for approximately three years at five sites on two …

Social And Cultural Factors Affecting Rates Of Regular Retreatment Of Mosquito Nets With Insecticide In Bagamoyo District, Tanzania, P.J. Winch, A.M. Makemba, V.R. Makame, M.S. Mfaume, M.C. Lynch, Zul Premji, J.N. Minjas, C.J. Shiff

Pathology, East Africa

Insecticide-treated mosquito nets have an impact on mortality and morbidity in young children under controlled conditions. When integrated into larger control programs, there is the danger that rates of regular retreatment of the nets with insecticide will drop, greatly limiting their effectiveness as a public health intervention. In Bagamoyo District, Tanzania, rates of retreatment dropped significantly when payment for the insecticide was introduced. A series of neighbourhood (hamlet) meetings were held in all study villages to discuss people's concerns about the insecticide and ways to increase rates of retreatment. Although changes were made in the procedure for retreatment, rates of …

What Is The Intimate Experience Of Couples Following The Woman's Cancer-Related Breast Surgery?, Lynne Amor

Theses: Doctorates and Masters

The purpose of this phenomenological study is to describe and interpret the experience of couples following the woman's surgery for breast cancer, in order to gain an in depth understanding of how this mutilating surgery affects their everyday lives. Breast cancer is the most prevalent form of cancer in Australian women, and in most industrialised nations. Women in Australia have a one in fourteen lifetime risk of developing the disease. Little is known concerning what meanings this surgery brings to the intimacy experienced between partners. It is important to seek knowledge of the phenomenon of intimacy, how the couples understand …

Tell Me A Story: Using Short Fiction In Teaching Law And Bioethics, Dena S. Davis

Law Faculty Articles and Essays

For some years now, I have been experimenting with the use of short stories. Despite rich resources for stories, there remains a void best filled by fiction. When discussing fiction, we can probe, criticize, and express ourselves freely without the constraints we feel when discussing real people. Good fiction lays bare the innermost thoughts and experiences of its characters, perhaps even their dreams and nightmares, in a way that would be intrusive, uncomfortable, or impossible, even in autobiography. When the entire class reads a short story, it provides a pool of shared experience, a fixed point for discussion. Just as …

The Effect Of Upper Extremity Immobilization Following Surgical Rotator Cuff Repair On Balance In Elderly Individuals, Edward S. Gagné, Rebecca L. Schneider

Masters Theses

The purpose of this study was to determine if a relationship exists between upper extremity immobilization following surgical rotator cuff repair and balance in elderly individuals. Twenty-eight healthy volunteers (nine with rotator cuff repair, nineteen without) aged 53 to 74 participated in the study. Balance was measured using the Berg Balance Measure, Modified Berg Balance Measure, Functional Reach Test, and force plate analysis. Results were analyzed using t-tests for paired and independent samples, Mann Whitney U (Wilcoxon Rank Sum W) tests and Wilcoxon Matched-Pairs Signed- Ranks tests. Significant differences were found between the post-rotator cuff surgery and control groups for …

A Preliminary Study Of Trunk Kinematics During Walking In Normal Subjects, Lisa R. Elders, Heather L. Greenwald, Celeste A. Sartor

Masters Theses

The purpose of this study was to systematically describe the three-dimensional trunk kinematics in normal subjects, to establish a baseline for comparison to future research in gait analysis and aid in the identification of pathological gait. Seventeen volunteers between the ages of twenty and fifty, who met criteria for normal subjects, participated in this study. Trunk kinematic data were collected using an optoelectronic technique. An ensemble average of trunk kinematic data in each of the cardinal planes was plotted in degrees of motion versus percentage of gait cycle. A distinct pattern of trunk kinematics during gait was found in this …