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Evaluating The Persian Versions Of Two Psoriatic Arthritis Screening Questionnairesearly Arthritis For Psoriatic Patients Questionnaire (Earp) And Psoriasis Epidemiologyscreening Tool (Pest) In Iranian Psoriatic Patients, Vahide Lajevardi, Seyed Zahra Ghodsi, Mahdieh Shafiei, Amir Teimourpour, Ifa Etesami
Evaluating The Persian Versions Of Two Psoriatic Arthritis Screening Questionnairesearly Arthritis For Psoriatic Patients Questionnaire (Earp) And Psoriasis Epidemiologyscreening Tool (Pest) In Iranian Psoriatic Patients, Vahide Lajevardi, Seyed Zahra Ghodsi, Mahdieh Shafiei, Amir Teimourpour, Ifa Etesami
Turkish Journal of Medical Sciences
Background/aim: The majority of psoriatic arthritis (PsA) patients present at dermatology clinics with cutaneous psoriasis up to 10 years prior to arthritis onset; therefore, applying a suitable screening tool to detect PsA early is essential for dermatologists. This study aimed to validate and evaluate the Persian version of two PsA screening questionnaires, the early arthritis for psoriatic patients questionnaire (EARP) and the psoriasis epidemiology screening tool (PEST) in Iranian psoriatic patients. Materials and methods: In this cross-sectional study, psoriatic patients who presented to the dermatology clinic without a previously established PsA were asked to fill out the Persian version of …
Lutein/Zeaxanthin Isomers Regulate Neurotrophic Factors And Synaptic Plasticity Intrained Rats, Cemal Orhan, Füsun Erten, Beşi̇r Er, Mehmet Tuzcu, Nurhan Şahi̇n, Öznur Ece Durmaz Kurşun, Vijaya Juturu, Kazi̇m Şahi̇n
Lutein/Zeaxanthin Isomers Regulate Neurotrophic Factors And Synaptic Plasticity Intrained Rats, Cemal Orhan, Füsun Erten, Beşi̇r Er, Mehmet Tuzcu, Nurhan Şahi̇n, Öznur Ece Durmaz Kurşun, Vijaya Juturu, Kazi̇m Şahi̇n
Turkish Journal of Medical Sciences
Background/aim: This study was conducted to elucidate the effects of lutein/zeaxanthin isomers (L/Zi) on lipid metabolism, oxidative stress, NF-ΚB/Nrf2 pathways, and synaptic plasticity proteins in trained rats. Materials and methods: Wistar rats were distributed into four groups: 1) control, 2) L/Zi: rats received L/Zi at the dose of 100 mg/kg by oral gavage, 3) exercise, 4) exercise+L/Zi: rats exercised and received L/Zi (100 mg/kg) by oral gavage. The duration of the study was eight weeks. Results: Exercise combined with L/Zi reduced lipid peroxidation and improved antioxidant enzyme activities of muscle and cerebral cortex in rats (p < 0.001). In the Exercise + L/Zi group, muscle and cerebral cortex Nrf2 and HO-1 levels increased, while NF-ΚB levels decreased (p
Allergic Bronchopulmonary Aspergillosis In Children, Özge Atay, Suna Asi̇lsoy, Gi̇zem Atakul, Serdar Al, Özge Kangalli Boyacioğlu, Nevi̇n Uzuner, Özkan Karaman
Allergic Bronchopulmonary Aspergillosis In Children, Özge Atay, Suna Asi̇lsoy, Gi̇zem Atakul, Serdar Al, Özge Kangalli Boyacioğlu, Nevi̇n Uzuner, Özkan Karaman
Turkish Journal of Medical Sciences
Background/aim: Allergic bronchopulmonary aspergillus (ABPA) is a lung disease caused by hypersensitivity from Aspergillus fumigatus. Diagnostic criteria, staging systems and treatment methods for ABPA disease have been reported in studies evaluating populations, the majority of which are adult patients. Our study aimed to discuss the use of ABPA diagnostic criteria in children, the success of other alternative regimens to oral corticosteroids in the treatment of ABPA, and the changes that occur during treatment, in the light of the literature. Materials and methods: Between January 2017 and 2020, patients diagnosed with ABPA at the Dokuz Eylül University Child Allergy and Immunology …
Incidence, Risk Factors, And Adverse Outcomes Of Acute Kidney Injury In Very Prematureneonates: A Single Center Experience, Nuran Üstün
Turkish Journal of Medical Sciences
Background/aim: Acute kidney injury (AKI) is a serious morbidity in premature neonates. The aim of this study was to determine the incidence of AKI and to evaluate its impact on morbidity and mortality in very premature infants. Materials and methods: This retrospective cohort study was conducted in the neonatal intensive care unit (NICU). A total of 410 preterm infants who were born before 32 gestational weeks were screened and 318 were included in this analysis. AKI was defined according to the modified neonatal Kidney Disease: Improving Global Outcomes criteria. Results: The incidence of AKI was 32.1% (102/318). Regression analyses revealed …
Pretreatment Serum Uric Acid Level Is Not A Surrogate Marker For The Outcome Offavipiravir Treatment In Covid-19 Patients, Ahmet Çağkan İnkaya, Emre Kara, Nursel Çalik Başaran, Taha Koray Şahi̇n, Oğuz Abdullah Uyaroğlu, Ömrüm Uzun, Serhat Ünal
Pretreatment Serum Uric Acid Level Is Not A Surrogate Marker For The Outcome Offavipiravir Treatment In Covid-19 Patients, Ahmet Çağkan İnkaya, Emre Kara, Nursel Çalik Başaran, Taha Koray Şahi̇n, Oğuz Abdullah Uyaroğlu, Ömrüm Uzun, Serhat Ünal
Turkish Journal of Medical Sciences
No abstract provided.
Transient Minimal Hydronephrosis On Contralateral Kidney In Infants With Unilateralhydronephrosis: Is It An Early Sign Of Worsening Of The Affected Kidney?, Mirzaman Huseynov, Rahşan Özcan, Şenol Emre, Nur Canpolat, Sebuh Kuruğoğlu, Haluk Burçak Sayman, Mehmet Eli̇çevi̇k, Yunus Söylet, Sabri̇ Nafi̇z Cenk Büyükünal, Haluk Emi̇r
Transient Minimal Hydronephrosis On Contralateral Kidney In Infants With Unilateralhydronephrosis: Is It An Early Sign Of Worsening Of The Affected Kidney?, Mirzaman Huseynov, Rahşan Özcan, Şenol Emre, Nur Canpolat, Sebuh Kuruğoğlu, Haluk Burçak Sayman, Mehmet Eli̇çevi̇k, Yunus Söylet, Sabri̇ Nafi̇z Cenk Büyükünal, Haluk Emi̇r
Turkish Journal of Medical Sciences
Background/aim: The criteria for surgical management of ureteropelvic junction obstruction are not well-defined, and there is a risk for loss of renal function before the operation. In this context, certain changes in contralateral kidney had been investigated in order to increase the sensitivity of diagnosis. In this study, we aimed to investigate whether contralateral transient minimal hydronephrosis (CTMH) can be considered as an "early alarm" sign for worsening of the affected kidney in infants with hydronephrosis. Materials and methods: A total of 182 infants (92 surgically treated and 90 conservatively followed-up) with unilateral hydronephrosis were retrospectively analyzed. Ultrasonography and renal …
Long Term Neurological Sequela Of Isolated Infarctions According To The Topographicareas Of Thalamus, Aygül Tanti̇k Pak, Zahi̇de Mai̇l Gürkan, Sebahat Nacar Doğan, Yildizhan Şengül
Long Term Neurological Sequela Of Isolated Infarctions According To The Topographicareas Of Thalamus, Aygül Tanti̇k Pak, Zahi̇de Mai̇l Gürkan, Sebahat Nacar Doğan, Yildizhan Şengül
Turkish Journal of Medical Sciences
Background/aim: Thalamus infarctions presented with various clinical findings are considered to be related to classical and variative infarction areas. In our study, we aimed to compare the sequela clinical findings of patients with isolated thalamus infarction according to anatomical areas. Materials and methods: Seventy patients diagnosed with isolated thalamus infarction in our clinic between 2010 and 2020 were included in the study. The infarction areas of the patients were divided into groups by the radiologist, including the variative areas to the classical areas using magnetic resonance imaging. Neurological examinations were performed and recorded. Sequela clinical findings of the groups were …
Is Conut Score A Prognostic Index In Patients With Diffuse Large Cell Lymphoma?, Gülsüm Akgün Çağliyan, Si̇bel Hacioğlu, Başak Ünver Koluman, Kadi̇r İlkkiliç, Ruki̇ye Nar, Mehmet Nuri̇ Başer, Asli Bozdemi̇r, Hande Şenol, Ni̇lay Şen Türk, Veysel Erol, Onurcan Yildirim, Ömer Çağliyan, Ni̇l Güler
Is Conut Score A Prognostic Index In Patients With Diffuse Large Cell Lymphoma?, Gülsüm Akgün Çağliyan, Si̇bel Hacioğlu, Başak Ünver Koluman, Kadi̇r İlkkiliç, Ruki̇ye Nar, Mehmet Nuri̇ Başer, Asli Bozdemi̇r, Hande Şenol, Ni̇lay Şen Türk, Veysel Erol, Onurcan Yildirim, Ömer Çağliyan, Ni̇l Güler
Turkish Journal of Medical Sciences
Background/aim: The aim of the study was to evaluate the effect of Controlling Nutritional Status (CONUT) score on the prognosis in patients with diffuse large B-cell lymphoma (DLBCL). Materials and methods: The present study was a retrospective study. The CONUT score was calculated based on serum albumin, total cholesterol and lymphocyte levels. This study included a total of 266 patients, 131 (49.2%) were female and 135 (50.8%) were male. The median follow-up period was 51 months (range: 1-190). Results: The median age was 64 years. The cut off CONUT was 1.5. There was a significant difference between patients with high …
Investigation Of The Effects Of Propofol/Ketamine Versus Propofol/Fentanyl On Nauseavomiting Administered For Sedation In Children Undergoing Magnetic Resonance Imaging:A Prospective Randomized Double-Blinded Study, Haci Semi̇h Gürcan, Ayşe Ülgey, Özlem Öz Gergi̇n, Si̇bel Seçki̇n Pehli̇van, Kara Mehmet Yildiz
Investigation Of The Effects Of Propofol/Ketamine Versus Propofol/Fentanyl On Nauseavomiting Administered For Sedation In Children Undergoing Magnetic Resonance Imaging:A Prospective Randomized Double-Blinded Study, Haci Semi̇h Gürcan, Ayşe Ülgey, Özlem Öz Gergi̇n, Si̇bel Seçki̇n Pehli̇van, Kara Mehmet Yildiz
Turkish Journal of Medical Sciences
Background/aim: In this study, we aimed to compare the effects of propofol-ketamine and propofol-fentanyl sedations on postprocedure nausea-vomiting in children undergoing magnetic resonance imaging (MRI). Materials and methods: This study included 100 pediatric patients (2-10 years old) who had propofol-ketamine and propofol-fentanyl for sedation to undergo MRI. The patients were divided into two groups, and sedation was performed through propofol-ketamine (Group K; n = 50) or propofol-fentanyl (Group F; n = 50). For sedation induction, intravenous (IV) bolus of 1.2 mg/kg propofol and 1 mg/kg ketamine were administered in Group K, IV bolus of 1.2 mg/kg propofol, and 1 µg/kg …
Flow Cytometric Analysis Of Platelet Surface Glycoproteins In The Diagnosis Of Thirty-Twoturkish Patients With Glanzmann Thrombasthenia: A Multicenter Experience, Berkay Saraymen, Sabahatti̇n Muhtaroğlu, Mustafa Yavuz Köker, Nazan Sarper, Emi̇ne Zengi̇n, Canan Albayrak, Davut Albayrak, Osman Bülent Zülfi̇kar, Sayi̇me Başak Koç Şenol, Esma Bentli̇, Semi̇h Yilmaz, Aysun Çeti̇n, Bülent Eser, Mustafa Çeti̇n
Flow Cytometric Analysis Of Platelet Surface Glycoproteins In The Diagnosis Of Thirty-Twoturkish Patients With Glanzmann Thrombasthenia: A Multicenter Experience, Berkay Saraymen, Sabahatti̇n Muhtaroğlu, Mustafa Yavuz Köker, Nazan Sarper, Emi̇ne Zengi̇n, Canan Albayrak, Davut Albayrak, Osman Bülent Zülfi̇kar, Sayi̇me Başak Koç Şenol, Esma Bentli̇, Semi̇h Yilmaz, Aysun Çeti̇n, Bülent Eser, Mustafa Çeti̇n
Turkish Journal of Medical Sciences
Background/aim: Glanzmann thrombasthenia (GT) is a rare autosomal recessively inherited bleeding disorder characterized by the quantitative (type 1 and type 2) or qualitative (type 3) deficiency in platelet membrane glycoprotein (GP) IIb/IIIa (CD41a/CD61) fibrinogen receptors. In type 1, 2, and 3, CD41a/CD61 expression is 5%, 5%-20% and above 20%, respectively. In this study, diagnosis of GT was confirmed and subgroups were identified in 32 Turkish patients by flow cytometry analysis. Materials and methods: CD41a/CD61 expression levels in platelet-rich plasma (PRP) obtained from peripheral venous EDTA blood samples were analyzed with a BD FACSCanto II flow cytometer (Becton Dickinson, Franklin Lakes, …
Synergistic Effect Of Vancomycin Combined With Cefotaxime, Imipenem, Or Meropenemagainst Staphylococcus Aureus With Reduced Susceptibility To Vancomycin, Arpasiri Srisrattakarn, Chonthicha Chaiyapoke, Sirikarn Booncharoen, Sujintana Wongthong, Aroonwadee Chanawong, Patcharaporn Tippayawat, Ratree Tavichakorntrakool, Aroonlug Lulitanond
Synergistic Effect Of Vancomycin Combined With Cefotaxime, Imipenem, Or Meropenemagainst Staphylococcus Aureus With Reduced Susceptibility To Vancomycin, Arpasiri Srisrattakarn, Chonthicha Chaiyapoke, Sirikarn Booncharoen, Sujintana Wongthong, Aroonwadee Chanawong, Patcharaporn Tippayawat, Ratree Tavichakorntrakool, Aroonlug Lulitanond
Turkish Journal of Medical Sciences
Background/aim: We investigated the synergistic effect between vancomycin and ß-lactams against vancomycin-susceptible (VSSA) and nonsusceptible MRSA isolates [heterogeneous vancomycin-intermediate S. aureus (hVISA) and VISA]. Materials and methods: A total of 29 MRSA, including 6 VISA, 14 hVISA, and 9 VSSA isolates, were subjected to a microbroth dilution-minimum inhibitory concentration (MIC) checkerboard using vancomycin combined with cefotaxime, imipenem, or meropenem. To confirm synergistic activity, the representative strains of VISA, hVISA, and VSSA were then selected for the time-kill curve method. Results: The combination of vancomycin with imipenem, meropenem, or cefotaxime exhibited synergistic effects against 17 (2 VISA, 9 hVISA, and 6 …
Histopathological Effects Of Aloe Vera On Wound Healing Process In Penile Fracture Model:An Experimental Study, Kadi̇r Turgay Akgül, Engi̇n Doğanteki̇n, Eli̇f Özer, Mustafa Sirri Kotanoğlu, Yusuf Gökkurt, Sema Hücümenoğlu
Histopathological Effects Of Aloe Vera On Wound Healing Process In Penile Fracture Model:An Experimental Study, Kadi̇r Turgay Akgül, Engi̇n Doğanteki̇n, Eli̇f Özer, Mustafa Sirri Kotanoğlu, Yusuf Gökkurt, Sema Hücümenoğlu
Turkish Journal of Medical Sciences
Background/aim: This study assessed the histopathological effects of aloe vera (AV) on penile fractures (PF) formed experimentally in rat model. Materials and methods: Thirty-two Wistar adult male rats (220 to 250 g) were used. The PF model was created experimentally with a number 15 lancet. After the interventions, all of the rats were randomly and equally divided into 4 groups. In the first group, incision was not closed (group C). In the second group, AV was locally applied onto incision without suturing for 3 days (group AV). In the third group, the incision line was closed primarily (group PR). In …
Galectin-3: Can It Be A Diagnostic Tool For Pneumonia In Covid-19 Patients?, Emi̇ne Kartal Baykan, Engi̇n Şebi̇n, Ömer Karaşahi̇n, Ahmed Rami̇z Baykan, Serkan Cerrah, Hasan Göğebakan, Can Sevi̇nç, Mustafa Kahraman, Yasemi̇n Coşkun Yavuz
Galectin-3: Can It Be A Diagnostic Tool For Pneumonia In Covid-19 Patients?, Emi̇ne Kartal Baykan, Engi̇n Şebi̇n, Ömer Karaşahi̇n, Ahmed Rami̇z Baykan, Serkan Cerrah, Hasan Göğebakan, Can Sevi̇nç, Mustafa Kahraman, Yasemi̇n Coşkun Yavuz
Turkish Journal of Medical Sciences
Background/aim: Biochemical markers are needed to show lung involvement in COVID-19 disease. Galectin-3 is known to play a key role in the inflammation and fibrosis process. We aimed to evaluate the predictive role of galectin-3 levels for pneumonia in patients with COVID-19. Materials and methods: Total of 176 patients with COVID-19, confirmed with reverse transcriptase polymerase chain reaction, admitted to the Erzurum Regional Training and Research Hospital was analyzed. The study was designed as a cross sectional. The baseline data of laboratory examinations, including galectin-3 were collected at the time of diagnosis. CT images evaluated by a single radiologist according …
Interleukin-21: A Potential Biomarker For Diagnosis And Predicting Prognosis In Covid-19 Patients, Ni̇lüfer Ayli̇n Acet Öztürk, Ahmet Ursavaş, Asli Görek Di̇lektaşli, Ezgi̇ Demi̇rdöğen, Necmi̇ye Funda Coşkun, Dane Edi̇ger, Ayşe Esra Uzaslan, Di̇ğdem Yöyen Ermi̇ş, Mert Karaca, Orkun Eray Terzi̇, Merve Bayram, Di̇lara Ömer Topçu, Büşra Yi̇ği̇tli̇ler, Ahmet Yurttaş, Shahri̇yar Maharramov
Interleukin-21: A Potential Biomarker For Diagnosis And Predicting Prognosis In Covid-19 Patients, Ni̇lüfer Ayli̇n Acet Öztürk, Ahmet Ursavaş, Asli Görek Di̇lektaşli, Ezgi̇ Demi̇rdöğen, Necmi̇ye Funda Coşkun, Dane Edi̇ger, Ayşe Esra Uzaslan, Di̇ğdem Yöyen Ermi̇ş, Mert Karaca, Orkun Eray Terzi̇, Merve Bayram, Di̇lara Ömer Topçu, Büşra Yi̇ği̇tli̇ler, Ahmet Yurttaş, Shahri̇yar Maharramov
Turkish Journal of Medical Sciences
Background/aim: COVID-19 patients have a wide spectrum of disease severity. Several biomarkers were evaluated as predictors for progression towards severe disease. IL-21 is a member of common γ-chain cytokine family and creates some specific effects during programming and maintenance of antiviral immunity. We aimed to assess IL-21 as a biomarker for diagnosis and outcome prediction in patients hospitalized with COVID-19. Materials and methods: Patients with a preliminary diagnosis of COVID-19 and pneumonia other than COVID-19 admitted to a tertiary care hospital were included consecutively in this comparative study. Results: The study population consisted of 51 patients with COVID-19 and 11 …
Reliability And Validity Of The Turkish Version Of Post-Covid-19 Functional Status Scale, Ebru Çalik Kütükcü, Aslihan Çakmak, Esra Kinaci, Oğuz Abdullah Uyaroğlu, Naci̇ye Vardar Yağli, Gülay Sai̇n Güven, Melda Sağlam, Lale Özişik, Nursel Çalik Başaran, Deni̇z İnal İnce
Reliability And Validity Of The Turkish Version Of Post-Covid-19 Functional Status Scale, Ebru Çalik Kütükcü, Aslihan Çakmak, Esra Kinaci, Oğuz Abdullah Uyaroğlu, Naci̇ye Vardar Yağli, Gülay Sai̇n Güven, Melda Sağlam, Lale Özişik, Nursel Çalik Başaran, Deni̇z İnal İnce
Turkish Journal of Medical Sciences
Background/aim: The post-COVID-19 Functional Status (PCFS) has recently been developed for functional outcomes of COVID-19 upon discharge and in long term. The purpose of this study was to investigate the reliability and validity properties of the Turkish version of the PCFS in Turkish post-COVID-19 patients with hospitalized and nonhospitalized during infection. Materials and methods: One hundred participants with post-COVID-19 were included in this cross-sectional study. Test-retest reliability of the Turkish version of PCFS assessed by intraclass correlation coefficient (ICC) and Cronbach's alpha was calculated for internal consistency. For construct validity, correlation coefficients between the Turkish version of PCFS developed by …
Intraoperative Ultrasound Imaging And Sono-Scintigraphic Concordance Improvessuccess Rates Of Minimally Invasive Parathyroidectomy, Rabi̇ye Uslu Erdemi̇r, İlhan Taşdöven, Taner Bayraktaroğlu, Güldeni̇z Karadeni̇z Çakmak
Intraoperative Ultrasound Imaging And Sono-Scintigraphic Concordance Improvessuccess Rates Of Minimally Invasive Parathyroidectomy, Rabi̇ye Uslu Erdemi̇r, İlhan Taşdöven, Taner Bayraktaroğlu, Güldeni̇z Karadeni̇z Çakmak
Turkish Journal of Medical Sciences
Background/aim: This study aimed to evaluate the effect of sono-scintigraphic correlation on the success of minimal invasive parathyroidectomy (MIP) via surgeon performed continuous intraoperative sonographic guidance in patients operated for primary hyperparathyroidism (PHPT) without intact parathormone (PTH) measurement. Materials and methods: A retrospective analysis of a prospective database was conducted to review patients who underwent MIP (July 2017-October 2019). The screened parameters were preoperative PTH level, preoperative ultrasonography (US), preoperative scintigraphy, intraoperative US, intraoperative frozen section analysis, postoperative PTH level, and permanent pathology report. Intraoperative intact PTH measurement was not employed due to institutional policy. Results: Preoperative US alone localized …
Mean Platelet Volume In Familial Mediterranean Fever Related Aa Amyloidosis Andcomparison With Common Primary Glomerular Diseases, Tolga Yildirim, Berranur Kütahya, Fatma İş, Mehmet Erdevi̇r, Müge Üzerk Ki̇bar, Neri̇man Sila Koç, Emi̇ne Arzu Ayhan, Şeref Rahmi̇ Yilmaz, Yunus Erdem
Mean Platelet Volume In Familial Mediterranean Fever Related Aa Amyloidosis Andcomparison With Common Primary Glomerular Diseases, Tolga Yildirim, Berranur Kütahya, Fatma İş, Mehmet Erdevi̇r, Müge Üzerk Ki̇bar, Neri̇man Sila Koç, Emi̇ne Arzu Ayhan, Şeref Rahmi̇ Yilmaz, Yunus Erdem
Turkish Journal of Medical Sciences
Background/aim: Compared to healthy controls, mean platelet volume (MPV) is frequently higher in patients with Familial Mediterranean fever (FMF) but lower in AA amyloidosis patients. The reason for the difference in MPV levels in FMF patients with and without AA amyloidosis is unclear. The aim of the study was to determine whether low MPV is unique to AA amyloidosis or MPV is similarly low in all glomerular diseases as a result of proteinuria and/or renal dysfunction. Materials and methods: We compared pre-biopsy MPV levels of patients with AA amyloidosis secondary to FMF, to MPV levels of patients with membranous glomerulonephritis, …
Risk Factors Related To The Size And Volume Of Femoral Artery Pseudoaneurysm Aftercatheter Angiography: A Single-Center-Study, Özgür Çakir, Zeki̇ Talas, Duygu Temi̇z Karadağ, Ayşegül Durmaz, İsa Çam, Ercüment Çi̇ftçi̇, Mühi̇p Kanko
Risk Factors Related To The Size And Volume Of Femoral Artery Pseudoaneurysm Aftercatheter Angiography: A Single-Center-Study, Özgür Çakir, Zeki̇ Talas, Duygu Temi̇z Karadağ, Ayşegül Durmaz, İsa Çam, Ercüment Çi̇ftçi̇, Mühi̇p Kanko
Turkish Journal of Medical Sciences
Background/aim: Evaluate the risk factors associated with pseudoaneurysms' development after the percutaneous interventional procedures performed by cardiology, interventional radiology (IR), and the other clinics. Materials and methods: We retrospectively analyzed the ultrasound scans in the hospital database and picture archiving system (PACS) and enrolled a total of 132 patients during the period from October 2015 and December 2019. We evaluated the maximum diameter and volume of the pseudoaneurysm with the patient and procedure-related factors with univariate analysis. Results: We found that the patients with hypertension and without peripheric artery disease (PAD) had greater sac diameter (p = 0.010 and p …
The Utility Of Magnetic Resonance Angiography In Children With Nutcracker Syndrome, Di̇lara Atasoy, Ayşegül Cansu, Ayşe Füsun Beki̇rçavuşoğlu, Eli̇f Bahat Özdoğan, Ali̇ Ahmetoğlu
The Utility Of Magnetic Resonance Angiography In Children With Nutcracker Syndrome, Di̇lara Atasoy, Ayşegül Cansu, Ayşe Füsun Beki̇rçavuşoğlu, Eli̇f Bahat Özdoğan, Ali̇ Ahmetoğlu
Turkish Journal of Medical Sciences
Background/aim: The presented study aimed to evaluate the utility of magnetic resonance angiography (MRA) in the pediatric population with nutcracker syndrome. Materials and methods: Patients with suggestive clinical symptoms and laboratory findings and got the diagnosis of nutcracker syndrome with Doppler ultrasonography between January 2011-2019 were included in the study. In addition, children who had renal MRA due to hypertension were evaluated as the control group. MRA images of all patients were examined retrospectively by three radiologists at different levels of experience, and the superior mesenteric artery angle, aorta-mesenteric distance, left renal vein diameter both in the regions of aorta-mesenteric, …
The Contribution Of Neurocognitive Situation, Physical Capacity And Daily Life Activities Toquality Of Life In Childhood Acute Lymphoblastic Leukemia Survivors, Eli̇f Keleş Gülnerman, Yağmur Çam, Bülent Elbasan, Şebnem Soysal, Zühre Kaya, İdi̇l Yeni̇cesu, Ülker Koçak
The Contribution Of Neurocognitive Situation, Physical Capacity And Daily Life Activities Toquality Of Life In Childhood Acute Lymphoblastic Leukemia Survivors, Eli̇f Keleş Gülnerman, Yağmur Çam, Bülent Elbasan, Şebnem Soysal, Zühre Kaya, İdi̇l Yeni̇cesu, Ülker Koçak
Turkish Journal of Medical Sciences
Background/aim: There are no extensive studies on the QL in children who completed acute lymphoblastic leukemia (ALL) treatment and currently living without any disease in Turkey. Our study aimed to analyze both the QL and the effects of physical, neurocognitive capacities on QL in childhood ALL survivors aged 7-12 years at the time of recruitment. Materials and methods: PedsQL cancer module 3.0 child and proxy report, for ages 5-7 and 8-12 years, WeeFIM scale, BOTMP Short Form, RPM, reading, writing, and mathematics assessment tools, sociodemographic information form were carried out to the children and their family. Results: There was no …
The Effects Of Vitamin D Supplemantation On Prognosis In Patients With Mildobstructive Sleep Apnea Syndrome, Feri̇de Ayyildiz, Hi̇lal Yildiran, Nigar Afandiyeva, Özlem Gülbahar, Oğuz Köktürk
The Effects Of Vitamin D Supplemantation On Prognosis In Patients With Mildobstructive Sleep Apnea Syndrome, Feri̇de Ayyildiz, Hi̇lal Yildiran, Nigar Afandiyeva, Özlem Gülbahar, Oğuz Köktürk
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to investigate the effect of vitamin D on the disease prognosis and biochemical parameters in patients with mild obstructive sleep apnea syndrome (OSAS). Materials and methods: Nineteen adult male individuals (18-65 years) who were diagnosed with mild OSAS after polysomnography and had low vitamin D levels were included in the study. Each week, patients took 50.000 IU Vitamin D3 supplementation for 8 weeks. Polysomnography, biochemical parameters FBG (fasting blood glucose), lipid profile (TG, TC, LDL-C, HDL-C, VLDL-C), calcium, phosphorus, parathormone, calcitonin, serum 25(OH)D, insulin, CRP, TNF-α, IL-6, and IL-10 of patients were evaluated …
Fatty Acid-Binding Protein-4 As A Biomarker Predicting Acromegaly-Associated Diabetesmellitus, Sema Hepşen, Pinar Akhanli, Hakan Düğer, Murat Çalapkulu, Beki̇r Uçan, Muhammed Erkam Sencar, Davut Sakiz, İlknur Öztürk Ünsal, Seyi̇t Murat Bayram, Mustafa Özbek, Erman Çakal
Fatty Acid-Binding Protein-4 As A Biomarker Predicting Acromegaly-Associated Diabetesmellitus, Sema Hepşen, Pinar Akhanli, Hakan Düğer, Murat Çalapkulu, Beki̇r Uçan, Muhammed Erkam Sencar, Davut Sakiz, İlknur Öztürk Ünsal, Seyi̇t Murat Bayram, Mustafa Özbek, Erman Çakal
Turkish Journal of Medical Sciences
Background/aim: The known pathogenesis of diabetes mellitus (DM) in acromegaly is mainly based on growth hormone (GH) and insulin-like growth factor-1 (IGF-1) excess. Fatty acid-binding protein 4 (FABP-4), a novel adipokine, is found to induce insulin resistance and type 2 DM. We aimed to investigate the possible effect of FABP-4 on glucose metabolism in patients with acromegaly. Materials and methods: This case-control study included 28 patients newly diagnosed with acromegaly and 57 healthy volunteers. The patients with acromegaly were classified according to their glycemic status as with DM, prediabetes, and normal glucose tolerance. Anthropometric measurements, laboratory test results, and FABP-4 …
Nondamaging Retinal Laser Therapy In Recurrent Diabetic Macular Edema After Antivegf Injections, Mehmet Çitirik
Nondamaging Retinal Laser Therapy In Recurrent Diabetic Macular Edema After Antivegf Injections, Mehmet Çitirik
Turkish Journal of Medical Sciences
Background/aim: Subthreshold yellow nondamaging retinal laser therapy (NRT) could provide a greater safety profile when compared to conventional laser methods. NRT may also improve diabetic macular edema (DME). This study aims to assess whether the severity of DME affects the efficacy of subthreshold yellow NRT. Materials and methods: The study included 70 eyes that had previously been treated with ranibizumab for DME and then developed recurrent macular edema, which was treated with NRT once. The central foveal thickness (CFT) and best-corrected visual acuity (BCVA) were evaluated retrospectively 2 months following the NRT. The eyes in the study were divided into …
Exercise Capacity, Muscle Strength, Dyspnea, Physical Activity, And Quality Of Life Inpreoperative Patients With Lung Cancer, Gülşah Barği, Ece Baytok, Zeli̇ha Çeli̇k, Merve Şatir Türk, Ali̇ Çeli̇k, İsmai̇l Cüneyt Kurul, Meral Boşnak Güçlü
Exercise Capacity, Muscle Strength, Dyspnea, Physical Activity, And Quality Of Life Inpreoperative Patients With Lung Cancer, Gülşah Barği, Ece Baytok, Zeli̇ha Çeli̇k, Merve Şatir Türk, Ali̇ Çeli̇k, İsmai̇l Cüneyt Kurul, Meral Boşnak Güçlü
Turkish Journal of Medical Sciences
Background/aim: To detect the extent to which physical impairments are observed in patients with lung cancer awaiting lung surgery, exercise capacity, muscle strength, physical activity, dyspnea, and quality of life (QOL) were objectively compared between the patients and healthy individuals in current study. Materials and methods: Patients with lung cancer (n = 26) and healthy individuals (n = 21) were included. Exercise capacity, respiratory (maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP)) and quadriceps femoris muscle strength, physical activity, dyspnea and QOL were evaluated using 6-min walk test (6-MWT), a mouth pressure device, a hand-held dynamometer, a metabolic holter device, …
Relationship Between C-Reactive Protein To Albumin Ratio And Coronary Artery Calciumscore And Cad-Rads Scores With Coronary Computed Tomography Angiography, Mehmet Aki̇f Erdöl, Kadri̇ye Gayretli̇ Yayla
Relationship Between C-Reactive Protein To Albumin Ratio And Coronary Artery Calciumscore And Cad-Rads Scores With Coronary Computed Tomography Angiography, Mehmet Aki̇f Erdöl, Kadri̇ye Gayretli̇ Yayla
Turkish Journal of Medical Sciences
Background/aim: C-reactive protein (CRP) to albumin ratio (CAR) is predictive marker of systemic inflammatory state in atherosclerotic coronary diseases when compared to predictive value of these two markers separately. We aimed to evaluate the relationship between CAR and the coronary artery calcium (CAC) score, Coronary Artery Disease-Reporting and Data System (CAD-RADS) score in patients' unknown diagnosis of coronary artery disease (CAD) underwent coronary CTA (Computed Tomography Angiography) and were classified by CAD-RADS scores. Materials and methods: A total of 187 patients consecutively referred for the evaluation of their chest pain underwent coronary CTA were included retrospectively. Results: CRP, CAR, and …
Effects Of Bevacizumab Administration On The Hypoxia - Induced Pulmonaryhypertension Rat Model, Canan Demi̇r, Meral Karaman, Eyüp Sabri̇ Uçan, Ali̇ Necati̇ Gökmen, Duygu Gürel, Şadi̇ye Canan Çoker, Yasemen Adali, Osman Yilmaz
Effects Of Bevacizumab Administration On The Hypoxia - Induced Pulmonaryhypertension Rat Model, Canan Demi̇r, Meral Karaman, Eyüp Sabri̇ Uçan, Ali̇ Necati̇ Gökmen, Duygu Gürel, Şadi̇ye Canan Çoker, Yasemen Adali, Osman Yilmaz
Turkish Journal of Medical Sciences
Background/aim: Bevacizumab is a chemotherapeutic drug, which selectively binds to vascular endothelial growth factor (VEGF) and mainly inhibits angiogenesis and neovascularization. We aimed to study the possible effects of bevacizumab on right ventricular pressure (RVP), right ventricular hypertrophy, and VEGF, in hypoxia - induced pulmonary hypertension (PH) rat model. Materials and methods: 24 adult Wistar Albino rats were randomly divided into four groups: control group - saline; Bevacizumab Group; PH Group; PH + Bevacizumab Group. In hypoxia - induced model, 10% oxygen and 90% nitrogen were applied in a plexiglas box for eight days to PH Group and PH + …
Effect Of Coronavirus Pandemic On Organ Donation And Transplantation In Turkey, Emi̇ne Gülşah Torun, Mutlu Uysal Yazici
Effect Of Coronavirus Pandemic On Organ Donation And Transplantation In Turkey, Emi̇ne Gülşah Torun, Mutlu Uysal Yazici
Turkish Journal of Medical Sciences
No abstract provided.
Effect Of Hyperparathyroidism On Coagulation: A Global Assessment By Modifiedrotation Thromboelastogram (Rotem), Göknur Yorulmaz, Ahmet Toygar Kalkan, Aysen Akalin, Eli̇f Sevi̇l Alagüney, Eren Gündüz, Bartu Badak, Betül Aydin Buyruk, Medi̇ne Nur Kebapçi, Fatma Belgi̇n Efe, Muzaffer Bi̇lgi̇n, Olga Meltem Akay
Effect Of Hyperparathyroidism On Coagulation: A Global Assessment By Modifiedrotation Thromboelastogram (Rotem), Göknur Yorulmaz, Ahmet Toygar Kalkan, Aysen Akalin, Eli̇f Sevi̇l Alagüney, Eren Gündüz, Bartu Badak, Betül Aydin Buyruk, Medi̇ne Nur Kebapçi, Fatma Belgi̇n Efe, Muzaffer Bi̇lgi̇n, Olga Meltem Akay
Turkish Journal of Medical Sciences
Background/aim: Hyperparathyroidism is an endocrine disorder characterized by hypercalcemia. Because of calcium?s effects on parathyroid glands, bone, intestines, and kidneys, it has an important place in homeostasis. The results of studies regarding hyperparathyroidism hemostasis are conflicting. Thromboelastography helps to evaluate all steps of hemostatic system. Our aim in this study was to investigate the possible role of hemostatic mechanisms in the development of thrombosis in hyperparathyroid patients with the modified rotation thromboelastogram (ROTEM). Materials and methods: Twenty-two patients with primary hyperparathyroidism (PHPT) and 20 healthy controls were involved. This study was conducted in Eskisehir Osmangazi University Faculty of Medicine, Endocrinology …
Can Thrombocytosis Or Thrombocytopenia Predict Complicated Clinical Course And30-Days Mortality In Patients With Pneumonia?, Razi̇ye Si̇nem Misirlioğlu, Ersi̇n Aksay, Emre Şanci, Kemal Can Tertemi̇z
Can Thrombocytosis Or Thrombocytopenia Predict Complicated Clinical Course And30-Days Mortality In Patients With Pneumonia?, Razi̇ye Si̇nem Misirlioğlu, Ersi̇n Aksay, Emre Şanci, Kemal Can Tertemi̇z
Turkish Journal of Medical Sciences
Background/aim: While several different scoring systems aim to determine the clinical outcomes for patients with pneumonia, there is limited emphasis on the platelet count. This study investigated the relationships between thrombocyte count and 30-day mortality and complicated clinical course of patients with pneumonia. Materials and methods: This prospective cross-sectional study enrolled patients over 18 years old with a diagnosis of pneumonia in the emergency department for six months. The primary outcome was to establish the relationship between platelet count, mortality, complicated clinical course, and initial vital parameters on admission. The secondary outcome was comparing the platelet count with mortality and …
Comparison Of Usg-Guided Or Landmark Approach Fascia Iliaca Compartment Blockfor Positioning In Elderly Hip Fracture Patients With Spinal Anesthesia: A Randomizedcontrolled Observational Study, Tuna Ertürk, İbrahi̇m Gündoğmuş, Temel Güner, Cengi̇z Yildirim, Ayşin Ersoy
Comparison Of Usg-Guided Or Landmark Approach Fascia Iliaca Compartment Blockfor Positioning In Elderly Hip Fracture Patients With Spinal Anesthesia: A Randomizedcontrolled Observational Study, Tuna Ertürk, İbrahi̇m Gündoğmuş, Temel Güner, Cengi̇z Yildirim, Ayşin Ersoy
Turkish Journal of Medical Sciences
Background/aim: Currently, the elderly population in the world is rapidly increasing due to technological developments and convenient access to health services. Due to comorbidities in elderly patients, hip fractures are frequently observed after exposure to environmental trauma. To reduce pain during positioning in spinal anesthesia, fascia iliaca compartment block (FICB) can be applied easily and reliably. In our study, we aimed to compare the analgesic effects and duration of fascia iliaca compartment blocks performed with USG guidance or the landmark approach methods for relieving spinal anesthesia position pain. Materials and methods: Our study included 100 patients undergoing operations due to …