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A Decade Of Heart Surgery And A Look Into The Future, Conrad R. Lam

Henry Ford Hospital Medical Journal

No abstract provided.

Percutaneous Absorption Of Betamethasone-17-Benzoate, George R. Mikhail

Henry Ford Hospital Medical Journal

Percutaneous absorption of betamethasone-17-benzoate, a new topical corticosteroid, was sufficient enough to result in adrenocortical suppression in patients with psoriasis or atopic dermatitis when 0.025% of the steroid cream was applied under occlusion to 30% or more of the body surface, using 9 gm or more of the preparation. The adrenal function returned to normal within a short time after the cream was discontinued.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Quantitative Determination Of C-Reactive Protein (Crp) By Micro-Double Diffusion Technic, Hajime Hayashi, Gerald A. Logrippo, Mary Perry

Henry Ford Hospital Medical Journal

C-reactive protein (CRP) determinations in serum have been evaluated by two methods: the capillary tube method (presently in use) and the double diffusion technic (a newly developed procedure standardized in this laboratory). Advantages of the double diffusion technic are (1) quantitation of CRP in milligrams per 100 ml of serum, (2) differentiation of CRP from non-specific precipitates often found in patients' sera, and (3) increased sensitivity. A normal range of CRP levels has been established by analyzing serum from 750 supposedly healthy blood bank donors. Ninety-five percent of the donor population possess less than 1.0 mg of CRP per 100 …

Hypophyseal Growth Hormone Ii. Interaction With Other Hormones, M. Saeed-Uz-Zafar, Raymond C. Mellinger, Lewis B. Morrow

Henry Ford Hospital Medical Journal

Growth hormone (GH) synthesis and release is controlled by hypothalamic GH releasing factor. Thyroid hormones, androgens and estrogens in physiologic concentrations enhance GH secretion but a controlling role for glucagon and vasopressin in GH release is not established. Under stress, ACTH directly facilitates GH release while the similar action of the catecholamines is mediated by the a-adrenergic receptors. Though physiologic doses of glucorticoids and progestins do not affect GH liberation, prolonged administration of medroxyprogesterone acetate or of glucocorticoids in high dosage will decrease blood levels or blunt Gti responsiveness. GH enhances the release of insulin. A shift in adrenal steroid …

Health Nurse Clinician: An Extended Role For The Professional Nurse, C. E. Rupe, Diana Downs, Diane L. Kerr, William W. Hardy

Henry Ford Hospital Medical Journal

A program to upgrade the level of nursing involvement in patient care has been established in conjunction with Wayne Slate University. Offered as a possible solution to the shortage of health care personnel, the master's degree program would result in an upward movement of medical personnel and provide more continuity of care to the patient. More specifically, the trained Health Nurse Clinician would be able to provide better nursing care because of the nurse's greater awareness of the patient's health problem. She (or he) could also free the physician from some of the time-consuming aspects of routine physical examination without …

Hfh In The News

Henry Ford Hospital Medical Journal

No abstract provided.

Effect Of Normal Menstrual Cycle On Platelet Adhesiveness, Janet Mak Yeung

Henry Ford Hospital Medical Journal

Platelet adhesiveness was measured at intervals during the menstrual cycle in six normal females. Three normal males were studied during the .tame period of time to serve as controls. There was a significant difference of the variation of platelet adhesiveness between the two groups during the period of 30 days. Five out of six females showed much greater fluctuation than the males. No definite trend was observed in the platelet adhesiveness of females in relation to the menstrual cycle in this preliminary study. A larger number of samples from the population will be necessary to obtain a more accurate result.

Mixed Gonadal Stroma Cell Tumor Of The Testicle: A Case Report, Gerald B. Farrow, Arthur J. Johnson

Henry Ford Hospital Medical Journal

A specialized gonadal stromal tumor of mixed nature found in a 20-year-old Negro male is reported. Although the tumor had been present for six to seven years, there was no evidence of metastases or of hormonal imbalance. Reference is made to the confusing nomenclature of these rare tumors.

Spectacular Elevations Of Serum Alkaline Phosphatase: Clinical And Pathological Correlation Roy B., Roy B. Patton

Henry Ford Hospital Medical Journal

The diseases responsible for extremely high serum alkaline phosphatase aclivily in 45 patients were proliferative bone disease (10 patients) and hepato-biliary tract disease (35 patients). Conditions found in these patients that are not usually thought to cause such high phosphatase levels were: drug-induced cholestasis (6 patients), non-malignant extra-hepatic bile duct obstruction (3 patients), biliary or portal cirrhosis (5 patients), and primary hyperparathyroidism with generalized osteitis fibrosa (1 patient).

Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research

Henry Ford Hospital Medical Journal

No abstract provided.

The Hypocalcemic Effects Of Actinomycin D And Mithramycin, Eduardo L. Reyes, Robert W. Talley

Henry Ford Hospital Medical Journal

Both actinomycin D and mithramycin are useful agents in the treatment of cancer. They can also produce hypocalcemia, a comparatively rare phenomenon in cancer. Two such cases are presented in detail. Neither patient had the classic symptoms of hypocalcemia. Instead, the clinical picture was more compatible with hypercalcemia. The mechanism of action of each drug is explained; therapeutic implications are made with regards to their synergistic effects when used in combination with the standard calcium-lowering agents. Attention is drawn to the inhibitory action of these two agents on the calcium-mobilizing effect of the parathyroid hormone. The hypocalcemic effects of these …

In Vitro Kidney Preservation Techniques, S. G. Dienst

Henry Ford Hospital Medical Journal

The advantages of adding hyperbaria, low flow perfusion, and protein colloid to hypothermia at 0° C for kidney preservation are described. The possibilities of longer preservation at higher temperatures are discussed.

Hypophyseal Growth Hormone: I. Control Of Secretion, M. Saeed Zafar, Raymond C. Mellinger, Lewis B. Morrow

Henry Ford Hospital Medical Journal

Growth hormone (GH) is a major hormone of the anterior pituitary gland. Once established, its secretion continues throughout life. GH was first recognized in 1866 as a factor controlling growth. More recently, it has been demonstrated as a vital regulator of fat, carboyhdrate and protein metabolism. In fact, GH influence on the intermediary metabolism is the major mechanism by which growth and development are regulated. Numerous hormonal and nonhormonal factors have been shown to modify the basic pattern of GH synthesis and secretion. In this article we have reviewed some of these nonhormonal factors.

Surreptitious Ingestion Of Oral Anticoagulants, Thomas H. Greidanus, Ellis J. Van Slyck, Raymond W. Monto

Henry Ford Hospital Medical Journal

Hypoprothrombinemia secondary to surreptitious ingestion of coumarin or indanedione anticoagulants may be a difficult diagnosis for the unsuspecting physician. Four such case reports are presented. The disease should be suspected if the prothrombin time is markedly elevated and the individual is associated with the medical profession or has had previous treatment with oral anticoagulants. The diagnosis is confirmed by finding a deficiency in Factors II (prothrombin), VII, IX, and X and the presence of the coumarin or indanedione anticoagulant in the blood. The motive generally is that of gaining attention rather than committing suicide. Liver disease. Vitamin K deficiency states …

Double Contrast Arthrography Of The Knee, Peter C. Larowe, Robert S. Ormond, Edwin Guise

Henry Ford Hospital Medical Journal

Arthrography is a safe and relatively simple diagnostic procedure which provides an accurate and graphic preoperative means of defining pathology of the knee. In those cases where the expeditious evaluation and diagnosis of knee injury are of prime importance, ie, the athlete and industrial compensation case, arthrography provides a significant contribution. The clinical pathological features, salient anatomy and technic of study of internal derangements of the knee are discussed. Selected double contrast arthrograms illustrate normal and abnormal findings. Arthrotomies were performed in 20 of the 32 patients in this study with a positive arthrogram-arthrotomy correlation of 85%.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Immunologic Status Of Uremic Patients, Gerald A. Logrippo, C. E. Rupe, Hajime Hayashi, Dean Lesher

Henry Ford Hospital Medical Journal

The immunologic status of 25 uremic patients was studied with a battery of tests evaluating the humoral and cytological aspects of immunity. The individual's humoral immune status was evaluated as follows: quantitation of the three major serum immunoglobulins (IgG, IgA and IgM) expressed in mg/100 ml of serum and compared to established normal clinical standards (±2 SD/mean); qualitation of IgG and IgM evaluated by specific virus antibody titers and antitoxin values associated with IgG and by isoagglutinin tilers of the ABO blood groups associated with IgM. Immunoglobulin status is grouped into hyper- and hypo-immunoglobulin variations from normal and correlated with …

Cephalexin: In Vitro And In Vivo Studies, Frank Cox Jr., Edward L. Quinn, Bienvenido G. Gatmaitan, Nancy Peterson

Henry Ford Hospital Medical Journal

Cephalexin, a derivative of cephalosporin C, produces high serum and urine concentrations after oral administration. In addition, it shows good activity in vitro against most gram-positive and some gram-negative organisms. This study reports the in vitro susceptibility to cephalexin of a series of clinical isolates, the serum levels and urine concentrations in human volunteers and the results of its use in infections due to susceptible organisms. Results of in vitro susceptibility testing reveal that cephalexin was effective against most strains of the gram-positive organisms tested — group A streptococci, pneumococci, and staphylococci — although the MIC's are higher than those …

Hfh In The News

Henry Ford Hospital Medical Journal

No abstract provided.

Surgical Treatment Of Portal Hypertension: Review Of Henry Ford Hospital Experience, Joseph P. Elliott Jr., Kian H. Wong, Roger F. Smith

Henry Ford Hospital Medical Journal

Of 146 operations performed for the complications of portal hypertension in the Henry Ford Hospital between 1927 and August 31, 1969, 114 were portasystemic shunts. Operative mortality, sequelae and long term survival were closely related to the state of the patients' liver function and the urgency of operation.

A Follow-Up Study Of Patients With Chronic Obstructive Lung Disease And Their Practice Of The Breathing Pattern, A. Theodora Djagia

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this descriptive survey was to do a follow-up study on patients with COPD to find out to what extent these patients have followed instruction to continue exercising the abdominal and diaphragmatic muscles, with the utilization of a breathing pattern. Literature was reviewed which revealed contradictory findings in regard to the physiological benefits of the use of the breathing pattern. Nine patients met the criteria and signed a consent sheet to be visited in their homes. An Observation Data Sheet and Interview Guide were the tools used to collect data. A point system was constructed and used with …

The Relationship Between The Lingual Surface Of The Maxillary Central Incisor And The Eminence Of The Mandibular Fossae, Robert A. Huffer

Loma Linda University Electronic Theses, Dissertations & Projects

Gnathologists have suggested that in order to prevent excessive wear on posterior teeth, alveolar bone loss due to traumatic occlusion, and temporomandibular Joint (TMJ) disturbances, the mandibular incisors should disclude the posterior teeth by moving along the lingual surfaces of the maxillary incisors as the condyles move down the articular eminence in protrusion. It is suggested that in order for this to occur, the lingual surface of the maxillary incisors should be steeper than the eminence.

A cephalometric technique was developed to accurately determine the anatomical form of the articular eminence. A regular orthodontic tracing of the head was done …

Adherence Of Men With Myocardial Infarction To Prescribed Exercise, Marsha Schwartz

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to find out if men with myocardial infarction followed exercise prescribed by the physician. The reasons the patients did or did not follow the exercise prescription were investigated.

An interview guide was used to gather the data for this exploratory study. The questions on the interview guide were designed to obtain information to compare the former exercise pattern of the patient to exercise after infarction. Adherence to the exercise prescription was also determined by the exercise reported in the interview. Fifteen male subjects who had myocardial infarction were interviewed in the hospital and after …

The Development Of Electrophysiological Techniques Allowing "In Situ" Measurement Of Electrical Changes Within Smooth Muscle Cells Of Mesenteric Micro-Vessels, William J. Willems

Master's Essays (1922 - )

The primary objective or this study is essentially to acquire further knowledge of the factors involved in the nervous and humoral control of vascular smooth muscle tone. The relative importance of the nervous and endogenous vasotropic humoral control or vasomotor tone under normal conditions as well as under conditions or hypotension can be evaluated, at least in part, by observing the electrical activity occurring in single vascular smooth muscle cells of the mesenteric microcirculation. This thesis describes: 1) the development of electrophysiological methods for the measurement of such activity in ''in situ" micro-vessels with circulation and innervation intact, and 2) …

An Analysis Of Orthodontic Treatment Results Employing Class Ii Armstrong Adjustable Intermaxillary Springs, Michael E. Shumate

Loma Linda University Electronic Theses, Dissertations & Projects

A study of orthodontic treatment results employing Class II Armstrong Adjustable Intermaxillary Springs was made on twenty-eight randomly selected patients which were treated by Dr. Maclay Armstrong.

The skeletal and dental changes observed during treatment with the Class II springs was compared with those results observed when comparable type malocclusions were treated with Class II elastics. A list of changes which were observed during treatment with Class II elastics was compiled from the literature using individual studies published by Ricketts, Creekmore and Hanes.

The study was based on the findings observed in the initial and final cephalometric radiographs. A statistical …

The Role Of The Articular Eminence In Mandibular Protrusion, Norman E. Corbett

Loma Linda University Electronic Theses, Dissertations & Projects

Since movements of the TMJ may be translatory, rotary, or both, the form of the articular eminence becomes an integral part of the anatomy of the joint and is important in an understanding of TMJ function. A cephalometric technique was developed to accurately determine the anatomical form of the articular eminence. From a series of cephalograms, taken in various mandibular positions, the protrusive condylar path was determined. This path was also determined from a gnathological recording technique. The paths obtained were observed to be the same. The condylar path and articular eminence curves were mathematically expressed by computer programmed quadratic …

A Comparative Roentgenographic Cephalometric Study Of The Facial Profile Of Orthodontic Patients Treated At Loma Linda University With Winners Of The "Smiles Of The Year" Contest, Romeo I. Stoll

Loma Linda University Electronic Theses, Dissertations & Projects

The "Smiles of the Year" winners and patients treated at Loma Linda University by the extraction or non-extraction approach were compared by linear and angular variables of skeletal, dental and soft tissue components. These findings were analyzed statistically to determine significant differences in the profile and detect the relationship between the integument and hard structures.

The following conclusions were drawn from this investigation to reflect the trend of treatment at Loma Linda University.

1. After treatment the patients had less skeletal convexity, but were more convexity than established standards.
2. The incisors of the patients treated by the extraction approach were less …

Sensory Stimulation To Produce Micturition In The Cerebral Vascular Accident Patient, Mary Alice Pearce

Loma Linda University Electronic Theses, Dissertations & Projects

An experimental study was conducted in a university and a convalescent hospital using eight female CVA patients with urinary incontinence to test the hypothesis that the experimental technique of icing and brushing LI dermatome skin area would increase the probability that the CVA patient would void within a prescribed time and place. A modified one group method was used in which the patient served as her own control by participating in two types of bladder training programs over an eight to twelve hour period for four consecutive days. Program A used the experimental technique; Program B omitted the experimental technique. …

Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research

Henry Ford Hospital Medical Journal

No abstract provided.