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The Development Of Pediatrics In The United States, Jay H. Mayefsky

Henry Ford Hospital Medical Journal

No abstract provided.

Duplication And Deletion 11q23-Q24 Recombinants In Two Offspring Of An Intrachromosomal Insertion ("Shift") Carrier, Miriam G. Forsythe, Hugh Walker, Lester Weiss, Jacquelyn R. Roberson, Maria J. Worsham, V. Ramesh Babu, Daniel L. Van Dyke

Henry Ford Hospital Medical Journal

Few examples of intrachromosomal insertions have been described. These usually result from deletion of a segment of chromosome material, with insertion of the deleted material elsewhere on the same chromosome. Previous insertional translocations have been identified through a proband who has either a deletion or a duplication of the inserted segment. We describe a family which has two probands, one with a duplication and one with a deletion of the inserted segment. The unbalanced chromosomes probably resulted from an uneven number of crossovers between the breakpoints in the chromosome 11 of the father, who carries a balanced intrachromosomal insertion of …

Serum Creatinine Concentrations In Healthy Newborns: Reference Ranges During The First Five Days Of Life, Jennie Andreson, Jaime Alfredo Zegarra, Carlos Alberto Estrada, Francis Dumler

Henry Ford Hospital Medical Journal

Serum creatinine concentrations were studied in 52 healthy, full-term infants (29 males and 23 females) during the first five days of life. At birth, mean serum creatinine concentration was 0.76 ± 0.13 mg/dL. At 6 hours of life, values increased to 0.97 ± 0.11 mg/dL (P < 0.001) and remained elevated for 24 hours. Values then returned to baseline so that serum creatinine concentrations were 0.81 ± 0.15 mg/dL at 48 hours and 0.6l ± 0.15 mg/dL at 3 to 5 days of age. At birth, serum creatinine concentrations were higher in males than in females (0.80 ± 0.13 versus 0.71 ± 0.11 mg/dL, respectively; P < 0.009). However, the increases in serum creatinine concentration observed after birth were similar in both sexes. This is the first report of a prospective longitudinal study of serum creatinine concentrations between birth and 3 to 5 days of age in a Hispanic population. In addition, data were analyzed by sex. The results are a useful reference for normal serum creatinine concentrations in early life.

The Pediatrician's Guide To Food Allergy, John A. Anderson

Henry Ford Hospital Medical Journal

Food allergy occurs in as many as 5% of infants less than 1 year old. Most food sensitivities disappear by age 3 to 4. Most immunologically mediated food allergy reactions are due to type I IgE mechanisms, with skin, gastrointestinal, and respiratory signs and symptoms the most common manifestations. U sing the double-blind, placebo-controlled food challenge (DBPCFC) technique and atopic dermatitis as a model, the most common foods to which children are allergic are cow's milk, eggs, peanuts, wheat, fish, and soy proteins. Anaphylactic sensitivity in older children often involves crustacean seafoods (eg, shrimp), nuts, peanuts, fish, and eggs. Such …

The Circumcision Decision: A Plea For Informed Consent, Theresa Spinelli

Henry Ford Hospital Medical Journal

No abstract provided.

Adolescent Pregnancy And Sexually Transmitted Diseases: Case Report, Ruby L. Holloway, Richard Smith

Henry Ford Hospital Medical Journal

More than 1 million teenagers become pregnant every year in the United States. Nearly one-half of the pregnancies are carried to term, while a similar number end in abortion. In Michigan this amounts to approximately 34,000 teenage pregnancies (ages 15 to 19). These adolescent patients have a high incidence of sexually transmitted diseases (STDs). Of the pregnant teens at Henry Ford Hospital. 60% present with one or more STDs. We discuss the case of a 13-year-old pregnant girl who presented at five weeks estimated gestation with gonorrhea, chlamydia, and appendiceal perforation, resulting in subsequent spontaneous abortion. Further discussion focuses on …

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Vital Signs, December 1988, Boonshoft School Of Medicine

Vital Signs

A sixteen page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Dietary And Hormonal Evaluation Of Men At Risk For Prostate Cancer, Donald J. Pusateri

Loma Linda University Electronic Theses, Dissertations & Projects

Relationships between dietary nutrients and plasma and fecal estrone, estradiol-17β, testosterone, and plasma prolactin levels were studied in young Seventh-day Adventist men: 18 nonvegetarians (NV), 20 lacto-ovovegetarians (LOV), and 15 vegans (V). Blood samples and 3 d dietary records were obtained. Contemporaneously collected diet composites and stool samples were analyzed for fiber. The vegetarians consumed significantly more fiber than the omnivores, while NVs and LOVs consumed more saturated fat than the Vs. Although plasma steroid hormone status did not differ, the Vs had significantly higher fecal estrogen levels than the NVs or LOVs. Plasma prolactin levels were significantly higher in …

Acute Care Bed Need In Maine: General Use Acute Care Facilities In Maine : Utilization, Occupancy Rates, And Bed Need Projected To 1990 And 1995, Stephen Greenberg

Maine Collection

Acute Care Bed Need in Maine: General Use Acute Care Facilities in Maine : Utilization, Occupancy Rates, and Bed Need Projected to 1990 and 1995

by Stephen Greenberg, Planning and Research Associate, Office of Data, Research, and Vital Statistics.

Prepared at the request of the Division of Planning, Bureau of Health, Maine Department of Human Services.

Produced under Appropriations 1310.4, 1305.1065 and 2210.2950 (November, 1988).

Contents: Overview and Discussion of Findings / Using the Data: An Example / List of Detailed Tables / Appendices

Physical Linkage Of The Genes For Platelet Membrane Glycoproteins Iib And Iiia., Paul F. Bray, Greg Barsh, Jean-Philippe Rosa, Xue Ya Luo, Ellen Magenis, Marc A. Shuman

Cardeza Foundation for Hematologic Research

The fibrinogen receptor on human platelets is a prototypic member of the integrin family and is composed of subunit glycoproteins IIb (gpIIb) and IIIa (gpIIIa) in a 1:1 stoichiometric ratio. We have isolated cDNA clones for gpIIb and gpIIIa and localized both genes to chromosome 17. In the current study, several approaches were used to localize and map the genes for gpIIb and gpIIIa. A preliminary evaluation of subchromosomal localization was performed by using a panel of mouse-human somatic cell hybrids that contain different amounts of the long arm of human chromosome 17. Southern hybridization to the DNA of these …

Population Amalgamation And Genetic Variation: Observations On Artificially Agglomerated Tribal Populations Of Central And South America, R Chakraborty, P E Smouse, J V Neel

Faculty, Staff and Student Publications

The interpretation of data on genetic variation with regard to the relative roles of different evolutionary factors that produce and maintain genetic variation depends critically on our assumptions concerning effective population size and the level of migration between neighboring populations. In humans, recent population growth and movements of specific ethnic groups across wide geographic areas mean that any theory based on assumptions of constant population size and absence of substructure is generally untenable. We examine the effects of population subdivision on the pattern of protein genetic variation in a total sample drawn from an artificial agglomerate of 12 tribal populations …

Update - October 1988, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- International Abortion Conference Convenes November 14-16
-- Clinical ethics intensives begin in January
-- LLU establishes Stahl fund
-- More on Ethics and Aging (Letter)

[ Tobacco Taxes: Are They Moral? ]
-- The Tobacco Tax and Health Protection Act of 1988
-- Why I Oppose the Tobacco Tax Initiative
-- Why I Favor the Tobacco Tax Initiative

-- Anencephalic Infants as Organ Donors (Report)

Digest Of The Philadelphia College Of Osteopathic Medicine (Fall 1988), Philadelphia College Of Osteopathic Medicine

Digest

The Fall 1988 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Four More on the Floor
• Osteopathic Accomplishments
• A Nursing Viewpoint on Medical Ethics
• On Campus
• Class Acts
• In Memoriam
• Calendar

Developmental Expression Of Pdgf, Tgf-A, And Tgf-J Genes In Preimplantation Mouse Embryos, Daniel A. Rappolee, Carol A. Brenner, Richard Schultz, David Mark, Zena Werb

Department of Obstetrics and Gynecology Research Publications

Control of growth and differentiation during mammalian embryogenesis may be regulated by growth factors from embryonic or maternal sources. With the use of single-cell messenger RNA phenotyping, the simultaneous expression of growth factor transcripts in single or small numbers of preimplantation mouse embryos was examined. Transcripts for platelet-derived growth factor A chain (PDGF-A), trans- forming growth factor (TGF)-a, and TGF- 1, but not for four other growth factors, were found in whole blastocysts. TGF-cx, TGF-(31, and PDGF antigens were detected in blastocysts by immunocytochemistry. Both PDGF-A and TGF-a were detected as maternal transcripts in the unferilized ovulated oocyte, and again …

Spinal Osteoporosis, Charles H. Chesnut Iii

Henry Ford Hospital Medical Journal

No abstract provided.

Metabolic Bone Disease In Children, Michael P. Whyte

Henry Ford Hospital Medical Journal

No abstract provided.

Clinical Case Presentations, Henry G. Bone Iii, Louis V. Avioli

Henry Ford Hospital Medical Journal

No abstract provided.

Parathyroid Hormone-Related Disorders, John P. Bilezikian, T. J. Martin

Henry Ford Hospital Medical Journal

No abstract provided.

Vitamin D Metabolism In Health And Disease, Norman H. Bell

Henry Ford Hospital Medical Journal

No abstract provided.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Clinical Disorders Of Bone And Mineral Metabolism, Michael Kleerekoper

Henry Ford Hospital Medical Journal

No abstract provided.

A Tribute To Dr. Boy Frame, John T. Potts Jr.

Henry Ford Hospital Medical Journal

No abstract provided.

Bone Remodeling, A. M. Parfitt

Henry Ford Hospital Medical Journal

No abstract provided.

Allied Disciplines, Stephen M. Krane

Henry Ford Hospital Medical Journal

No abstract provided.

Paget Bone Disease And Heredity: A Case Report, Donato Agnusdei, Roberto Civitelli, Angelo Camporeale, Carlo Gennari

Henry Ford Hospital Medical Journal

Evidence on familial aggregation of Paget disease of bone shows that the trait is controlled by a single dominant gene. Due to the late onset of the disease, the primary biochemical abnormalities leading to the characteristic roentgenographic features are still unknown. We report the case of a 24-year-old woman who had an elevated serum alkaline phosphatase on routine analysis. Family history revealed that her father and paternal grandmother had Paget bone disease. This pattern is compatible with an autosomic dominant inheritance. Complete laboratory workup confirmed high heat labile alkaline phosphatase values, along with high serum osteocalcin and urinary hydroxyproline excretion. …

Metabolic Bone Disease And The Hip, Robert Lindsay

Henry Ford Hospital Medical Journal

No abstract provided.

Miscellaneous Disorders Of Calcium And Bone Metabolism, Gregory R. Mundy

Henry Ford Hospital Medical Journal

No abstract provided.

Newer Therapies In Hypercalcemia And Metabolic Bone Disease, Hunter Heath Iii

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.