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Beta-Adrenergic Blocking Agents In The Treatment Of Patients After A Myocardial Infarction, Sidney Goldstein

Henry Ford Hospital Medical Journal

Beta-adrenergic blocking agents have been widely used in ischemic heart disease. They have achieved their greatest benefit in the secondary prevention of recurrent events in patients following acute myocardial infarction (Ml). This is a review of the major clinical investigations exploring the effects of beta-adrenergic blocking agents in patients following acute Ml and in a variety of patient subsets. These data indicate that the routine use of beta-adrenergic blocking agents in postinfarction patients results in a 25% to 35% decrease in mortality and has increased relative and absolute benefit in patients with ventricular ectopy and left ventricular dysfunction. The adverse …

Special Feature: Management Of Acute Myocardial Infarction: Introduction, Mihai Gheorghiade

Henry Ford Hospital Medical Journal

No abstract provided.

Prehospital Care Of Acute Myocardial Infarction: A Review, Asit R. Gokli, Jay L. Kovar, Terry Kowalenko, Richard M. Nowak

Henry Ford Hospital Medical Journal

Each year more than 1 million people in the United States suffer from acute myocardial infarction (Ml) with most of the deaths occurring within hours of symptom onset. Over the last 25 years, different prehospital systems have evolved throughout the world which allow early cardiac monitoring and treatment of acute Ml patients. Thrombolytic therapy in acute Ml has been shown to decrease mortality and preserve left ventricular function when administered early after onset of symptoms. The potential role of Emergency Medical Services or Mobile Coronary Care Units in achieving early thrombolysis is under investigation. Several studies of prehospital interventions to …

Calcium Channel Blockers In The Management Of Myocardial Infarction Patients, Mihai Gheorghiade

Henry Ford Hospital Medical Journal

No abstract provided.

Recent Concepts In Clinical Psychiatry: Drug Treatment In Schizophrenia, Shahin H. Hussain

Department of Psychiatry

No abstract provided.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Neuroendocrine Responses To Acute Myocardial Infarction, Arlene B. Levine, T. Barry Levine

Henry Ford Hospital Medical Journal

No abstract provided.

Recovery Of Left Ventricular Function Following Acute Myocardial Infarction, Hani N. Sabbah, Paul D. Stein, Mihai Gheorghiade

Henry Ford Hospital Medical Journal

No abstract provided.

Biochemical Diagnosis Of Myocardial Infarction, Craig C. Foreback

Henry Ford Hospital Medical Journal

A rapid, sensitive, and specific marker for the diagnosis of acute myocardial infarction (MI) and the assessment of reperfusion following thrombolytic therapy has been sought by research workers for years. Creatine kinase-MB (CK-MB) is the best biochemical marker currently available to the cardiologist and the emergency room physician for the assessment of patients presenting with symptoms of acute Ml. CK-MB is best measured using immunoassay techniques at 3- to 4-hour time intervals during the first 12 hours after onset of.symptoms. Other currently available markers include lactate dehydrogenase and its isoenzymes and myoglobin. Future developments include assays for troponin, reported to …

The Role Of Echocardiography In Acute Myocardial Infarction, Mohsin Alam

Henry Ford Hospital Medical Journal

Our institutional experience with two-dimensional echocardiography and color flow Doppler tests, as welt as a review of the literature, reveals that echocardiography is useful in diagnosing myocardial infarction. Furthermore, complications of myocardial infarction such as mitral regurgitation with or without papillary muscle rupture, acquired ventricular septal defect, true and false left ventricular aneurysms, left ventricular thrombi, right ventricular infarction, and pericardial effusion in the setting of acute infarction can he detected by cardiac ultrasound. Echocardiography is also useful in assessing prognosis of postinfarction patients based on degree of left ventricular dysfunction. This test, however, is not 100% sensitive and specific …

Antiplatelet And Anticoagulant Therapy In Acute Myocardial Infarction, Syed M. Jafri

Henry Ford Hospital Medical Journal

No abstract provided.

Thrombolytic Therapy In Acute Myocardial Infarction: An Emergency Department Perspective, Bradford L. Walters

Henry Ford Hospital Medical Journal

No abstract provided.

Lidocaine Prophylaxis In Acute Myocardial Infarction, James E. Tisdale

Henry Ford Hospital Medical Journal

The prophylactic administration of lidocaine for the prevention of primary ventricular fibrillation (VF) following suspected acute myocardial infarction (Ml) is controversial. The incidence of primary VF following acute Ml ranges from 1.8% to 10.5%. "Warning arrhythmias" have not been shown to be reliable predictors of VF. In-hospital prophylactic administration of lidocaine has been shown to decrease the incidence of primary VF. whereas prehospital administration has not. However, prophylactic administration of lidocaine has not been shown to have a beneficial effect on mortality and may in fact increase mortality. The incidence of lidocaine-induced adverse effects during prophylaxis ranges from 4% to …

Diagnosis And Management Of Tachycardias After Myocardial Infarction, Charles R. Webb

Henry Ford Hospital Medical Journal

No abstract provided.

Role Of Coronary Angioplasty In Acute Myocardial Infarction, Susheel K. Sharma, Kenneth Retter, Fareed Khaja

Henry Ford Hospital Medical Journal

No abstract provided.

Surgical Treatment Of Acute Myocardial Infarction, Arthur R. Dresdale, Gaetano Paone

Henry Ford Hospital Medical Journal

In recent years, advances in surgical techniques and perioperative management of cardiac surgical patients have facilitated more aggressive operative treatment of many serious and even catastrophic complications of acute myocardial infarction (Ml). In addition, improved understanding of the natural history of these complications has helped to optimize the indications for and timing of surgical intervention. The role of emergency revascularization for postinfarction angina, evolving acute MI, cardiogenic shock after acute MI, and failed percutaneous transluminal angioplasty has expanded with overall satisfactory to excellent results. Surgical treatment of mechanical complications of acute Ml such as free-wall rupture, acute ischemic mitral insufficiency, …

Caring For The Acute Myocardial Infarction Patient: A Nursing Perspective, Denise L. Crimaldi Adams, Sandra R. Perez

Henry Ford Hospital Medical Journal

Cardiac nursing is nearly 30 years old. Changes in the rote of cardiac nursing have directly corresponded to the three distinct medical phases of care for the acute myocardial infarction patient—arrhythmia detection, pump failure, and limiting infarct size. Nursing care delivery in the cardiac setting, the cardiac patient, and the role of the cardiac nurse each have undergone changes over the years, which together has provided a challenge to health care delivery. Future effects of technological and pharmacologic advances, social changes, and nursing professional practice issues on cardiac care delivery are imperative to consider as health care moves into the …

Incomplete Versus Complete Myocardial Infarction, Mihai Gheorghiade, Sidney Goldstein

Henry Ford Hospital Medical Journal

Incomplete myocardial infarction (MI), when compared with a complete Ml. is characterized by a small infarct size and a large mass of viable but jeopardized myocardium within the perfusion zone of the infarct-related vessel that is manifested clinically by early recurrent infarction. The pathophysiology involves early spontaneous or thrombolytic reperfusion. Clinical (i.e., residual ischemia), electrocardiographic, and echocardiographic findings and magnitude of serum cardiac enzyme elevations should be taken into account in diagnosing an incomplete MI.

Post Myocardial Infarction Risk Stratification: 1991 Perspective, Michael Lesch

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Management Of Cardiogenic Shock Complicating Acute Myocardial Infarction: The Henry Ford Hospital Experience And Review Of The Literature, Ali R. Moosvi, Mihai Gheorghiade, Sidney Goldstein, Fareed Khaja

Henry Ford Hospital Medical Journal

Cardiogenic shock complicating acute myocardial infarction (MI) carries a high mortality which in some series prior to 1980 exceeded 80%. Neither the use of inotropic and vasopressor agents nor intraaortic balloon counterpulsation was found to improve survival in this group of patients. Intravenous thrombolytic agents improve survival in patients with acute MI, but their role in cardiogenic shock is unknown. Reports of the use of surgical and mechanical interventions in patients with severe left ventricular dysfunction were examined to determine if there was any benefit to be derived from restoring blood flow to ischemic areas of the myocardium. It was …

Sertoli Cell Only Syndrome (Secos): Lessons From Case Studies, Jamsheer J Talati, Hizbullah Sheikh

Section of Urology

Between June 85 and December 87, 69 testicular biopsies were submitted for histopathological examination during investigation of infertility; ten (14%) patients had a Sertoli cell only syndrome. The history, clinical features, and hormonal profiles were analyzed in an attempt to categorize these patients on aetiological basis. Two followed treatment of malignancy--one by radiation for testicular cancer and one by cyclophosphamide for a lymphoma. One had unilateral cryptorchidism. Mumps was etiological factor in one patient. FSH levels determined in 6 patients were elevated in all suggesting a possible dependence of (sick) Sertoli cells on spermatogenic cells for production of inhibin. Alternative …

Collagenous Colitis, Z Abbas, S Abid, S Hamid, W Jafri, H Khan

Section of Gastroenterology

No abstract provided.

Expression Of A Human Cartilage Procollagen Gene (Col2a1) In Mouse 3t3 Cells., Leena Ala-Kokko, James Hyland, Carol Smith, Kari I. Kivirikko, Sergio A. Jimenez, Darwin J. Prockop

Department of Medicine Faculty Papers

Expression in a recombinant system has been difficult to obtain for any of the major fibrillar collagens that require processing by eight or more post-translational enzymes. Here, two DNA constructs were designed so that the promoter region of the gene for the pro-alpha 1(I) chain of human type I procollagen drove expression of the human type II procollagen gene in mouse NIH 3T3 cells, a culture line that normally synthesizes type I procollagen but not any cartilage-specific protein such as type II procollagen. Both constructs were expressed as both mRNA and protein. In clones expressing the construct at high levels, …

A 5 Year Retrospective Case Study Of Penetrating Ocular Trauma At The Aga Khan University Hospital, Karachi, S Qarab Hasnain, Muzaffar Kirmani

Section of Ophthalmology

Ocular Trauma is an important cause of monocular visual impairment and blindness in younger age groups. We examined the cases of hospitalized ocular trauma from 1st January, 1985 through 30th July, 1990 using hospital medical records. The study comprised 27 patients (28 eyes), 51.8% of whom were under 16. The male-female ratio was 2.8:1. Right eye was more commonly involved (66.6%) and one patient had bilateral ruptured globes. Children at play were most vulnerable (33.3%) followed by road accidents which was the major cause (29.6%) in adults. Sixteen (64.0%) eyes suffered some complications and their mean duration of presentation after …

[Review Of] Male Sexual Health, Robert A. Aken

Library Faculty and Staff Publications

No abstract provided.

Hepatic Dysfunction In Falciparum Malaria, J Khan, J Akhter, H Sheikh, W Jafri

Department of Pathology and Laboratory Medicine

No abstract provided.

Current Concepts In The Diagnosis And Management Of Childhood Asthma, Z A. Bhutta

Department of Paediatrics and Child Health

No abstract provided.

Female Condoms, An Urgent Need, Mary Guinan

School of Public Health Faculty Research

As of February 1991, more than 16,000 cases of AIDS in women had been reported in the United States, but the ". tidal wave of cases in women is yet to come. World Health Organization (WHO) estimates of the number of women infected with the human immunodeficiency virus (HIV) range from 1.5 million in Africa to I 00,000 in the United States. Within the next ten years, the majority of these women will develop AIDS and die. Some will live a bit longer, but all are eventually doomed to die prematurely. Most will not live to see their 40th year.

Oncolog, Volume 36, Issue 03, July-September 1991, Emil J. Freireich Md, James M. Bowen Phd

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• From cell culture to clinical protocol: In cancer research, the goals of scientist and clinician converge New clinic treats depressed cancer patients
• Half-century of progress in leukemia research