Digital Commons Network^™

Ms211: Marnie, Armin Weinberg

Works on Radiation Effects: 1990-2020

A letter of recommendation for Marnie Rose's application to medical school. Marnie matriculated to UTHouston started a Pediatric Residency but passed away due to a glioblastoma. Her family started http://www.drmarnierose.org/ a foundation that continues today. This letter provides a nice summary of her past interest and work related to Chernobyl. See more at Armin Weinberg, PhD Papers and its finding aid.

University Of New England Board Of Trustees: Capital Campaign Newsletter 1995-6, University Of New England

William Kirmes, D.O. Collection

A newsletter updating the recipient on the progress of the University of New England Capital Campaign.

Ciprofloxacin In Multi-Resistant Infections In Childhood: An Audit, D M. Khan, Z A. Bhutta

Department of Paediatrics and Child Health

Ciprofloxacin is a new orally administrable fluoroquinolones, with considerable efficacy against multiresistant organisms. Its use in the paediatric age group however, is controversial because of the risk of potential articular toxicity. We retrospectively reviewed ciprofloxacin usage over a 32 week periods (June, 1991-September, 1993) in paediatric inpatients at The Aga Khan University Hospital. Ciprofloxacin was used in 21 cases, singly in 11 (52%) and in combination with other antibiotics in a further 10 (48%). The response to therapy was adjudged as 'good' or 'fair' in 13 (62%) cases. Ciprofloxacin was the only sensitive antibiotic in 4 (19%) and resistance to …

Posttraumatic Stress Disorder In Parents Of Traumatic Brain Injury Patients, Carol Farr

Loma Linda University Electronic Theses, Dissertations & Projects

Traumatic Brain Injury (TBI) produces cognitive, behavioral, and affective deficits with resulting problems such as improper social behavior, increased aggression, emotional, personality and characterological changes. The impact upon the survivor, the sibling, as well as the parental subsystem has been well documented in the literature. Post-Traumatic Stress Disorder (PTSD) has been diagnosed in several different types of trauma survivors, although rarely have individual psychological symptoms been studied in parents.

This research examined the possible vulnerability factors that are associated with TBI and their potential influence upon PTSD symptomology. Questionnaires were mailed to 266 parents of TBI patients with a response …

Predicting Intentions Of Physical Therapy Students To Practice Primary Prevention, Sharon Potter Anderson

Loma Linda University Electronic Theses, Dissertations & Projects

Physical therapy (PT) has traditionally been a hands-on, tertiary-care field. Although the American Physical Therapy Association has mandated a broader perspective, little primary prevention is yet being reported in the U. S. An attitude change toward prevention must occur if physical therapists can be expected to become involved in preventive physical therapy. The purpose of this project was to determine predictors of physical therapy student intention to perform primary prevention with a questionnaire based on Ajzen's Theory of Planned Behavior. The theory uses attitude, subjective norm and perceived control to predict intention based on beliefs and strength of beliefs in …

A Model Of Cytomegalovirus Association With The Development Of Heart Graft Atherosclerosis, Evan Skowronski

Loma Linda University Electronic Theses, Dissertations & Projects

The development of graft atherosclerosis in heart transplant recipients has been associated with the development of post-transplant cytomegalovirus infection. The mechanism of this involvement, however, remains unclear. I undertook a study to determine the role of cytomegalovirus in the development of graft atherosclerosis. First, a rapid method of detecting cytomegalovirus based on capillary polymerase chain reaction and gel electrophoresis was employed to determine the presence of cytomegalovirus in a wide variety of clinical samples. Detection of cytomegalovirus is a lengthy procedure under normal conditions, and timely detection of cytomegalovirus in transplant recipients may allow intervention early enough to block the …

Uhs-Communicator: May/June/July 1995, University Of Health Sciences College Of Osteopathic Medicine, Uhs-Com Alumni Association

Communicator (1991-2012)

Contents: 1995 Commencement -- UHS Foundation Contributors -- Mary Lou Butterworth, D.O. Accepts Position as Acting UHS Foundation President -- Oklahoma City Bombing -- One Graduate's Success: Mary Sue Kendrick, D.O. -- News -- Alumni Association's Corner of the World.

Diagnostic Evaluation Of Pleural Effusion And The Role Of Needle Pleural Biopsy, S F. Hussain, S Mujahid, J A. Khan

Section of Pulmonary & Critical Care

No abstract provided.

An 800-Year-Old Physician – Surgeon Researcher Who Fits The Neuro Mold, George M. Austin

The Dr. George M. Austin Neurology Research Collection

Dr. Austin's copy of the McGill Neurosurgical Reunion Book of Abstracts. The file contains the Authors Index and Dr. Austin's abstract. Presented May 1995 for the Aneurysm-Stroke Research Foundation. Dr. Austin's complete copy of the book is available for use at Loma Linda University, Department of Archives and Special Collections.

Persistent Oral Dyskinesias Induced By Long-Term Haloperidol Treatment Is Dissociated From Changes In Neostriatal B(Max) And Mrna Content For Dopamine D(2) Receptors, Nuoyu Huang

Electronic Theses and Dissertations

Due to the presumed associations of dopamine (DA) receptor supersensitivity phenomena in both long-term neuroleptic-treated tardive dyskinetic rats and neonatal 6-hydroxydopamine (n6-OHDA)-lesioned rats, we studied the influence of haloperidol on n6-OHDA-lesioned rats. At 3 days after birth rats received 6-OHDA-HBr (200 $\mu$g, bilateral intracerebroventricularly; desipramine pretreatment, 20 mg/kg, 1h) or vehicle. Two months later haloperidol (1.5/kg/day $\times$ 2 days/week for 4 weeks, then 1.5 mg/kg/day, every day for 10 months) was added to the drinking water. Spontaneous oral activity of intact and n6-OHDA-lesioned rats receiving haloperidol was reached and maintained at significantly higher levels after 15 weeks of haloperidol treatment. …

Moraxella (Branhamella) Catarrhalis: A Molecular Epidemiology Study, Lyndell R. Gill

Electronic Theses and Dissertations

Moraxella (Branhamella) catarrhalis is the third-most-frequently isolated microorganism associated with acute exacerbations of chronic bronchitis in patients during their stay at the Mountain Home VA Medical Center (MHVAMC). In order to develop a practical, epidemiologically-meaningful typing method for M. (B.) catarrhalis, we tested two methods based on analysis of chromosomal DNA for typeability, reproducibility, and ability to differentiate between unrelated strains (discriminatory power, D). M. (B.) catarrhalis isolants from MHVAMC from 7/1/87-6/30/88 were grown overnight in broth and embedded in agarose. DNA was isolated by standard methods. The DNA was subjected to: (1) restriction endonuclease digestion (with either Bgl II …

Indomethacin Reduces Splenic Red Pulp Macrophage Populations In Female New Zealand White Rabbits, Thane S. Thurmond

Electronic Theses and Dissertations

In an effort to elucidate the mechanism by which indomethacin (IN) attenuates the stimulatory effect of estradiol (E$\sb2$) on rabbit splenic red pulp macrophages (RPM), thirty-nine female New Zealand White rabbits were divided into 10 groups: ovariectomized (OVX), OVX/IN at 0.1 and 5.0 mg/kg body weight (bw)/day; sham OVX (SOVX), SOVX/IN at 0.1 and 5.0 mg/kg bw/day; OVX/25 mg E2, OVX/25 mg E$\sb2$/IN at 0.1 and 5.0 mg/kg bw/day; intact Control. Quantitative changes in RPM population in response to the treatments were measured using a 0 to 4 histologic grading scale. Estradiol treatment resulted in increased RPM grade when compared …

Increased Alpha 1(I) Procollagen Gene Expression In Tight Skin (Tsk) Mice Myocardial Fibroblasts Is Due To A Reduced Interaction Of A Negative Regulatory Sequence With Ap-1 Transcription Factor., Neena Philips, Reza I. Bashey, Sergio A. Jimenez

Department of Medicine Faculty Papers

The TSK mouse, a model of fibrosis, displays exaggerated connective tissue accumulation in skin and visceral organs including the heart. To study the mechanisms of myocardial fibrosis in TSK mice, we established several strains of TSK mice myocardial fibroblasts in culture and examined the regulation of collagen gene expression in these cells. These strains displayed increased collagen gene expression in comparison with myocardial fibroblasts established from normal mice. On an average, the TSK myocardial fibroblast cultures showed a 4-fold increase in collagen synthesis and 4.4- and 3.6-fold increases, respectively, in alpha 1(I) and alpha 1(III) collagen mRNA steady state levels. …

Vital Signs, Spring 1995, Boonshoft School Of Medicine

Vital Signs

A twenty four page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Digest Of The Philadelphia College Of Osteopathic Medicine (Spring 1995), Philadelphia College Of Osteopathic Medicine

Digest

The Spring 1995 issue of the Digest of the includes the following articles:

• President's Perspective
• PCOM Leads the Way in GME
• Campaign Passes $3 Million Mark
• Memorial Service Honors Daniel L. Wisely, DO
• PCOM Profile
• Student Achievements
• PCOM Students Awarded Scholarships
• Robert S. Maurer, DO, '62: Caring for the Future
• PCOM: Never UnConventional in the Springl
• POMA Elects Officers
• PCOM Welcomes Five Board Members
• Campus Update
• Class Acts
• In Memoriam
• Coming Events
• Last Chance to Support Golf Classic Ad Book!

Mathematical Models Of Chemotherapy, John Carl Panetta

Mathematics & Statistics Theses & Dissertations

Several mathematical models are developed to describe the effects of chemotherapy on both cancerous and normal tissue. Each model is defined by either a single homogeneous equation or a system of heterogeneous equations which describe the states of the normal and/or cancer cells. Periodic terms are added to model the effects of the chemotherapy. What we obtain are regions, in parameter space (dose and period), of acceptable drug regimens.

The models take into account various aspects of chemotherapy. These include, interactions between the cancer and normal tissue, cell specific chemotherapeutic drug, the use of non-constant parameters to aid in modeling …

A Change Of Il-2 And Il-4 Production In Patients With Helicobactor Pylori Infection, X. G. Fan, Javed Yakoob, X. J. Fan, P. W. N. Keeling

Section of Gastroenterology

Helicobactor pylori is the most common cause of gastroduodenal inflammation. However, the exact immune pathogenesis is not fully understood. To look for evidence of the immunological mechanism in H. pylori associated disease, we measured cytokine interleukin-2 (IL-2) and IL-4 levels produced by peripheral blood lymphocytes (PBL) and gastric biopsies in 20 subjects with or without H. pylori infection. H. pylori can stimulate IL-2 and IL-4 production from PBL in H. pylori negative as well as H. pylori positive individuals. The spontaneous IL-2 production by PBL and gastric biopsies was greater (p < 0.0025, <0.001)in H. pylori negative individuals than that in H. pylori infected patients. Increased IL-4 levels from PBL in H. pylori infected patients were found in the presence of H. pylori (p < 0.0025). An increased spontaneous production of IL-4 from gastric biopsies was also observed in H. pylori infected patients (p < 0.025). In conclusion, an enhanced type 2 cytokine production was observed in H. pylori infected patients, which may be responsible for H. pylori chronic infection.

Polyclonal Mycobacterium Avium Infections In Patients With Aids: Variations In Antimicrobial Susceptibilities Of Different Strains Of M. Avium Isolated From The Same Patient., C Fordham Von Reyn, Nicholas J. Jacobs, Robert D. Arbeit, Joe N. Maslow, S Niemczyk

Dartmouth Scholarship

Broth microdilution MICs were determined for pairs of strains isolated from five AIDS patients with polyclonal Mycobacterium avium infection. Four (80%) of the five patients were infected simultaneously with strains having different antimicrobial susceptibility patterns. These findings have implications for the interpretation of susceptibility data in M. avium prophylaxis and treatment trials.

Cholera Admissions In Adults 1989-1994: A Hospital Based Study, Z Abbas, S M. Jafri, S Abid, H Khan

Section of Gastroenterology

In order to gain insight into the distribution of cholera over the years and proportion of monthly admissions under our adult medical services, we scrutinized our records of hospital discharges between 1989 and 1994. Only culture positive cases were included. Each year most of the cases of cholera are admitted between May and November with almost disease free interval from December to April. In 1992 admission rate was 4.24/1000 medical admissions which increased to 12.65 in 1993 and 13.73 in 1994. Though the Vibrio cholerae 01 Ogawa was the major isolate upto May, 1993, Vibrio cholerae non-01 serogroup 0139 dominated …

Ms211: First Trip To Kazakhstan Executive Summary, Armin Weinberg

Works on Radiation Effects: 1990-2020

This Executive Summary report gives a synopsis of our FIRST trip from February 12-21, to the city of Semipalatinsk, Kazakhstan that established the AIHA, TMH, BCM partnership. Great first impressions and orientation to what follows. A lot of prep went into this including getting letters from key Texas players including one from Governor George W. Bush, Texas to Governor Galimzhan B. Jakianov. ee more at Armin Weinberg, PhD Papers and its finding aid.

Ms211: Working Notes From First Trip To Kazakhstan, Armin Weinberg

Works on Radiation Effects: 1990-2020

Includes great material & notes eg, "ADW and CL returned to Semipalatinsk with BT’s car and driver. Unfortunately while returning they hit a patch of ice and ended up in a snowy ditch. Fortunately this occurred near one of the few villages along the way and a passing truck was able to pull them out. The good reflexes and driving skills of the driver kept them from overturning. ML and MR hired a car and driver from Kuchartov and returned later after completing the hospital survey" I (ADW) gave the drive $100 for pulling us out it was below zero …

Microwave Oven--Not Only For Cooking, S Pervez

Department of Pathology and Laboratory Medicine

No abstract provided.

Uhs-Communicator: March/April 1995, University Of Health Sciences College Of Osteopathic Medicine, Uhs-Com Alumni Association

Communicator (1991-2012)

Contents: Educational Pavilion -- UHS Foundation -- News -- Alumni Association's Corner of the World.

Thrombolytic Therapy In Acute Myocardial Infarction In Pakistan., M. Asad Karim, Ata Ata-Ur- Rehman Qureshi, Syed Faisal Mahmood, J. Akhter

Department of Medicine

To characterize features of acute myocardial infarction (AMI) in a Pakistani population, and assess the role of thrombolysis in our country, we studied 194 consecutive admitted patients with enzyme positive AMI. Males were affected three times more frequently; women, although affected less, had a higher incidence of complications than men. Premature coronary artery disease (CAD) was present in 50% patients presenting with AMI. An unusually high incidence of anterior wall myocardial infarction (39%) was seen. Complications were frequent with a predominance of LV failure symptoms. Cardiogenic shock was associated with a very high mortality, in excess of 93%. Streptokinase (SK) …

Cosmetic Trauma Surgery., Geoffrey G. Hallock Md

Department of Surgery

No abstract provided.

Ms211: Background & History Of Kazakhstan, Armin Weinberg

Works on Radiation Effects: 1990-2020

Some background and history about Kazakhstan including USSR period to provide early context for us as we entered the AIHA partnership. See more at Armin Weinberg, PhD Papers and its finding aid.

Ms211: Initial Thoughts About Aiha Kazakhstan Partnership In Semipalatinsk, Armin Weinberg

Works on Radiation Effects: 1990-2020

Notes by Armin that look at issues and opportunity for us with this AIHA partnership in Kazakhstan. The core of course with our internal BCM, TMH, TCH, TMC benefits. Obviously with possible links to our work in Chernobyl and even the AMC business as well. See more at Armin Weinberg, PhD Papers and its finding aid.

Sustained Release Drug Delivery Devices, Thomas J. Smith, Paul Ashton, Paul A. Pearson

Ophthalmology and Visual Science Faculty Patents

A method and device for treating a mammalian organism to obtain a desired local or systemic physiological or pharmacological effect is provided. The method includes administering a sustained release drug delivery system to a mammalian organism in need of such treatment at an area wherein release of an effective agent is desired and allowing the effective agent to pass through the device in a controlled manner. The device includes an inner core or reservoir comprising the effective agent; a first coating layer, which is essentially impermeable to the passage of the effective agent; and a second coating layer, which is …

Health Professions Division Catalog 1995-1996, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Feasability Of Preventing Encrustation Of Urinary Catheters, J. M. Bibby, A. J. Cox, D. W. L. Hukins

Cells and Materials

Colonization of urinary catheters by bacteria which produce urease leads to an increase in urine pH, followed by deposition of the minerals struvite and hydroxyapatite. Adhesion of these encrusting deposits can be reduced, but not prevented, by using catheters with a smooth surface finish. Chemical methods for preventing encrustation are not completely satisfactory. A better way of preventing encrustation would be to prevent colonization of the catheter by bacteria. This might be achieved by controlled release of antimicrobial agents directly into the urine from the catheter itself. Preliminary experiments have demonstrated the feasibility of controlled release from solid silicone. However, …