Digital Commons Network^™

Necrotizing Enterocolitis In Infants Weighing Less Than 2000 G, P Mufti, Z A. Bhutta

Department of Paediatrics and Child Health

Over a 4 year period, nine of 180 (5%) infants weighing less than 2000 G, admitted to the Aga Khan University Hospital (AKUH) developed necrotizing enterocolitis (NEC). An outbreak of NEC occurred in 1989, during which six infants developed the clinical illness. Overall incidence was 1.1%. Thirty-one birth weight and gestation matched controls were selected for comparison. Risk factors usually considered as predisposing factors, i.e., low 5 min Apgar score, rate of maternal complications, respiratory distress syndrome, mechanical ventilation, umbilical catheterisation, patient ductus arteriosus, use of antibiotics and feeding practices were found with equal frequency in both cases and controls. …

A Comparison Of Standard-Dose And High-Dose Epinephrine In Cardiac Arrest Outside The Hospital, Charles G. Brown, Daniel R. Martin, Paul E. Pepe, Harlan Stueven, Richard O. Commins, Edgar Gonzalez, Michael Jastremski, The Multicenter High-Dose Epinephrine Study Group

Emergency Medicine Publications

BACKGROUND.

Experimental and uncontrolled clinical evidence suggests that intravenous epinephrine in doses higher than currently recommended may improve outcome after cardiac arrest. We conducted a prospective, multicenter study comparing standard-dose epinephrine with high-dose epinephrine in the management of cardiac arrest outside the hospital.

METHODS.

Adult patients were enrolled in the study if they remained in ventricular fibrillation, or if they had asystole or electromechanical dissociation, at the time the first drug was to be administered to treat the cardiac arrest. Patients were randomly assigned to receive either 0.02 mg of epinephrine per kilogram of body weight (standard-dose group, 632 patients) …

Elder-Caregiving Among University Employees: Responsibilities And Needs, Constance L. Coogle, Edward F. Ansello

Virginia Center on Aging Publications

Although many institutions of higher education often house the researchers who study eldercare, few have documented the need for information and services among their estimated 460,000 employees who face the difficult task of effectively balancing work and eldercare responsibilities. Even fewer have established programs to address this need.

Drs. Constance Coogle and Edward Ansello have recently completed an exhaustive survey of VCU employees (N = 11,430) to determine the extent to which they provide care to disabled parents or spouses.[1] A longer, more detailed survey was sent to those who indicated that they were eldercaregivers to measure their perceived …

Finding Hiv-Infected Women - The Clinician's Role, Mary Guinan

School of Public Health Faculty Research

An estimated 100,000 women are currently infected with the human immunodeficiency virus (HIV) in the United States, and a great majority of them are unaware of their condition. Approximately 20,000 HIV-infected women were identified through publicly funded HIV screening programs in 1989 and 1990, and an unknown number through private screening. Because most HIV-infected women are believed to be in the lower socioeconomic strata, it is unlikely that a significant number were identified in the private sector. Therefore, up to 80% of HIV-positive women may not know they are infected.

Family Physicians, Chiropractors, And Back Pain, Peter Curtis, Geoffrey M. Bove

Biomedical Sciences Faculty Publications

In this article, major aspects of back care provided to patients by family physicians and chiropractors are reviewed, and the recent guidelines on spinal manipulation therapy are discussed. These guidelines should be useful for family physicians wishing to refer patients to chiropractors.

Trichotillomania, Shahin H. Hussain

Department of Psychiatry

No abstract provided.

Ms211: Background Examples Of Literature Searches On Topics Of Interest, Armin Weinberg

Works on Radiation Effects: 1990-2020

A zip file of various literature searches & some resources related to our work related to exposure after the Chernobyl accident and as we began looking at helping in Semey Kazakhstan----a collection of literature reviews on various topics we were interested in... eg. establishing a registry of those exposed for longterm follow-up, what we knew about certain areas like genetics and some resources like "A Guide to Environmental Resources" on the Internet by Carol Briggs-Erickson and Toni Murphy which could be found on the Internet and was written to be used by researchers, environmentalists, teachers and any person who is …

Oncolog, Volume 37, Issue 02, April-June 1992, Ralph S. Freedman Md, Phd, Bartlett D. Moore Iii,Phd, Nicholas H.A. Terry Phd

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• The primacy of patient welfare
• Potential doubling time of tumors may be the key to accurate prognosis, appropriate treatment
• Cognitive deficits in survivors of childhood cancers

Influence Of Donor Age On The Survival Of Human Embryonic Dopaminergic Neural Grafts, T. B. Freeman, G. M. Nauert, P. R. Sanberg, J. H. Kordower

Neurosurgery and Brain Repair Faculty Publications

No abstract provided.

Oncolog, Volume 37, Issue 03, July-September 1992, Scott M. Lippman Md, Mark A. Schusterman M.D., Eva Singletary Md, Merrick I. Ross M.D., Daryl Ogden Ms

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Retinoic acid/interferon combination shows promising response rates
• Cross-matching test helps find donors for patients in dire need of platelets
• Silicone gel-filled implants: Women should have the option to choose

Digest Of The Philadelphia College Of Osteopathic Medicine (Winter - January 1992), Philadelphia College Of Osteopathic Medicine

Digest

The Winter - January 1992 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Vision and Values: President’s Perspective
• 1991·92 Annual Fund: A Tradition of Support
• Founders Day 1992
• Emanuel Fliegelman, '42: A Born Teacher with Doctors and Patients
• United Again: Not Getting Older – Getting Better
• HPCOM Brings Health Awareness to the Community
• New Department Created as HPCOM Continues its Mission of Delivering Quality Care
• On Campus
• Just Published
• Class Acts
• In Memoriam
• Coming Events

Platelets And Leucocyte Counts In Pregnancy, Saadiya Aziz Karim, Javaid H. Rizvi, Iffat Rizwana, Mohammad Khurshid, Sadiqua N. Jafarey

Department of Obstetrics & Gynaecology

A study involving the obstetric clinic population of 3 major teaching hospitals of Karachi has been conducted to define changes in leucocyte and platelet counts as pregnancy progresses. 573 “normal” pregnant women - 183 in the first trimester, 195 in the second trimester and 194 in the third trimester were included in this analysis. We have found leucocytosis to be a feature of normal pregnancy; the change is subsequent to a progressive increase in granulocytes. Platelet counts were found to decrease slightly as pregnancy progresses

Role Of Thymectomy In Myasthenia Gravis, Sohaila Mohsin Ali, Aziz Sonawalla, Irfan Altafullah, Hizbullah Sheikh

Section of Urology

Thirteen patients with myasthenia gravis underwent total thymectomy between January, 1988 and December, 1991. The duration of symptoms prior to surgery varied from 2 months to 20 years. In a follow-up ranging from 2 months to 4 years, 11 patients showed a significant improvement with either complete discontinuation of medication of a marked reduction in doses. One patient with a small benign thymoma showed some improvement but subsequently required stepping up of anticholinesterase medication and addition of steroids and immune suppressants; another patient with atrophic thymic tissue had complete remission after thymectomy but developed myasthenic symptoms six months later requiring …

Germbuster Brainteaser: A Novel Education Tool, Andrew Sirotnak, Md, Joel D. Klein, Md, Stephen C. Eppes, Md

Department of Pediatrics Faculty Papers

As part of the Pediatric Infectious Diseases elective at the Alfred I. duPont Institute, pediatric residents from the Medical Center of Delaware and the Thomas Jefferson Medical College are encouraged to contribute original, educational material to our Germbusters newsletters. We thought readers of the Delaware Medical Journal would enjoy seeing one of the more innovative resident contributions.

Prevalence Of Iron Deficiency Anaemia In Children Of The Urban Slums Of Karachi, Ayesha Molla, Mohammad Khurshid, A. Majid Molla

Department of Pathology and Laboratory Medicine

A preliminary baseline survey was conducted to estimate the prevalence of anaemia in a group of 391 children aged 6-60 months, randomly selected from three urban slums of Karachi. Haemoglobin and the red cell indices including haematocrit, MCV, MCH, MCHC, ABC and red cell distribution width (RDW) were estimated for each of the selected children. Ferritin estimation was done on 354 (9 1%) children to assess the iron storage status. According to WHO criteria, the accepted cut-off point for anaemia screening in children is set at 11 gm/dl, 70 fI and 20 pg for haemoglobin, MCV and MCH respectively. Following …

Letter To The Editor., Wanda W. Young Scd, Stanley J. Smith Md, Facs, Joseph C. Young Md, Facs, Michael Rhodes Md, Facs

Department of Surgery

No abstract provided.

Radiation Induced Tumor Lysis Syndrome In Patients With Leukemia, Imtiaz A. Malik, Paul Vellozo, Mohammad Khurshid, M. Ata Khan

Department of Medicine

Tumour lysis syndrome is a catastrophic complica­lion of treatment of certain neoplasms. It is usually seen with the tumours that have high growth fractions, increased bulk and extreme sensitivity to cytotoxic therapy. Most commonly it occurs in association with hematologic malignancies such as lymphomas and leukaemias. Rarely it has been observed with solid tumours like small cell lung cancer, seminoma and carcinoma of the breast. The syndrome develops due to massive cell lysis occurring within a few hours to a few days of starting the cytotoxic therapy. It is characterized by hyperuricemia, hyperkalemia, hyperphosphatemia and hypocalcaemia. Acute renal failure, cardiac …

Eosinophilic Gastroenteritis, S H. Shah, Z Abbas, S Abid, H Shaikh, T Qaseem, H Khan

Section of Gastroenterology

No abstract provided.

Supervised Training Of Practical Procedures In The Internal Medicine Residency, Z Abbas, S Abid, J A. Khan, A Jabbar

Section of Gastroenterology

In order to get feedback whether the medical residents are getting adequate supervised training to perform practical procedures, a questionnaire was distributed among the residents asking their involvement in sixteen frequently performed procedures in the medical unit of the Aga Khan University Medical Centre. Though the residents were satisfied about their training in doing lumbar punctures, pleural and peritoneal aspirations, bone marrow aspiration and trephine and chest tubes placement, they showed their concern about training in putting central lines, venous cut downs, cardiac pacing and biopsies. A better schedule training programme, organized subspecialty rotation, continuous evaluation of resident's skill, credentialing …

Yet Another Cause Of Chronic Viral Hepatitis?, H A. Shah, S Abid, S Hamid, S W. Jafri, Z Abbas, T Qaseem, H Shaikh, A H. Khan

Section of Gastroenterology

The clinical features, course and histology of liver in 20 patients; mostly middle aged to elderly females, closely resembling chronic Non A Non B hepatitis is presented. They presented quite late in their disease and therefore, complications such as variceal bleeds, ascites and encephalopathy were frequent. Our patients were negative for hepatitis B and C virus serology. Metabolic and immune causes of chronic liver disease were also ruled out. To the best of our knowledge, this is the first study of its kind elaborating the clinical features, course and histology of liver in chronic Non B Non C hepatitis and …

Enterolithiasis Secondary To Intestinal Tuberculosis, M Y. Sheikh, I H. Rizvi, S A. Naeem, I Ahmad

Department of Radiology

No abstract provided.

Regulation Of Transforming Growth Factor-Beta 1 Gene Expression By Glucocorticoids In Normal Human T Lymphocytes., O. Ayanlarbatuman, A. P. Ferrero, Arturo Diaz, Sergio A. Jimenez

Department of Medicine Faculty Papers

Glucocorticoids (GC) modulate immune function in a number of ways, including suppression of T cell proliferation and other IL-2-mediated T cell functions. These inhibitory effects are similar to those induced by transforming growth factor-beta 1 (TGF-beta 1), a cytokine with potent T cell inhibiting activities. We examined the hypothesis that GC effects may be at least partially achieved through modulation of the expression of the TGF-beta 1 gene in activated T cells. Normal T cells were cultured with or without purified phytohemagglutinin (PHA-p) and 4 beta-phorbol 12-myristate 13-acetate (PMA) in the presence or absence of the synthetic GC, dexamethasone (100-200 …

Digest Of The Philadelphia College Of Osteopathic Medicine (Fall 1991), Philadelphia College Of Osteopathic Medicine

Digest

The Fall 1991 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Renovations and New Construction Continue
• PCOM Fundraising Goes Back to Basics
• Curriculum Changes
• President's Perspective
• Geriatric Care to be Stressed Early, Often
• PCOM Hosts Conference in Osteopathic Hospitals and Medical Education
• Unique DO-MBA Program Teaches the Business of Medicine
• PCOM Students Go Far for Rural Clinical Experience
• Where are Our 111 Residents?
• On Campus
• A "3-D" View of the Future
• Class Acts
• In Memoriam
• Coming Events

Congenital Pyloric Atresia And Epidermolysis Bullosa, Zafar Nazir, Zeba Batool Attar, Farhat Moazam

Section of Paediatric Surgery

Congenital pyloric atresia with epidermolysis bul­losa is recognized as a rare but distinct entity which is uniformly fatal^1,2. Until 1990 only 20 cases have been reported in the English literature^3,4. We present an additional case managed at the Aga Khan University Hospital to demonstrate the difficulties encountered in the management of such infants.

Instrumentation And Control For A Microprocessor-Based Coronary Perfusion System, Daniel L. Priester

Master's Theses (1922-2009) Access restricted to Marquette Campus

No abstract provided.

Vital Signs, October 1991, Boonshoft School Of Medicine

Vital Signs

A nine page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Statistical Interpretation Of Dna Typing Data, R Chakraborty

Faculty, Staff and Student Publications

No abstract provided.

Special Feature: Management Of Acute Myocardial Infarction: Introduction, Mihai Gheorghiade

Henry Ford Hospital Medical Journal

No abstract provided.

Recent Concepts In Clinical Psychiatry: Drug Treatment In Schizophrenia, Shahin H. Hussain

Department of Psychiatry

No abstract provided.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.