Digital Commons Network^™

Hereditary Sclerocornea, David Barsky, Steven P. Dunn

Henry Ford Hospital Medical Journal

A rare case of total hereditary sclerocornea is presented along with clinical history, histopathology, and a review of the possible pathogenesis and current literature on the subject. It is quite possible that imperfect cleavage of the anterior chamber angle may be the predisposing factor in scleralization of the cornea due to a failure of neural crest cell differentiation. If surgical intervention to correct for the corneal opacification is indicated, corneal transplantation should be performed as soon as possible after birth, similar to the indications for removal of dense congenital cataracts to avoid deprivation amblyopia.

Primary Hyperparathyroidism: Changing Patterns In Presentation And Treatment Decisions In The Eighties, D. Sudhaker Rao

Henry Ford Hospital Medical Journal

No abstract provided.

Dermatomyositis Complicated By Thrombotic Thrombocytopenic Purpura, Maria A. Sawdyk, Jeffrey Jundt

Henry Ford Hospital Medical Journal

A 65-year-old woman who had a documented history of dermatomyositis was hospitalized for evaluation of a syncopal attack. During the course of her stay, she experienced progressive neurologic dysfunction, hemolytic anemia, and thrombocytopenia. A clinical diagnosis of thrombotic thrombocytopenia purpura (TTP) was made, and therapy was initiated with glucocorticoids, plasmapheresis, plasma infusion, and antiplatelet medication. The pathogenesis of TTP has not been cleady elucidated. However, reports in the literature have postulated immune damage of the endothelium with demonstration of IgM and complement deposits as the origin of the condition. Further, there are reported cases of TTP associated with collagen disorders …

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

The Effectiveness Of Stimulation Therapy For The Cognitively Impaired Elderly, Sylvia H. Old

Community & Environmental Health Theses & Dissertations

The effectiveness of stimulation therapy for the cognitively impaired elderly living in an institution was assessed. Residents with varying degrees of cognitive impairment were treated with twenty, thirty-minute daily periods of reality orientation, reminiscence, resocialization, remotivation, and other stimulating therapies and were compared with a control group_ receiving no intervention. Treatment effects were assessed with a variety of instruments reflecting functioning across several domains. Included were ability to perform both basic self-care functions and activities of daily living, cognitive performance, affect, and satisfaction with the care received and the living environment in the nursing home. The experimental group was divided …

Current Concepts Of Metabolic Functional Imaging With Positron Emitters, John W. Keyes Jr.

Henry Ford Hospital Medical Journal

Positron emitting radionuclides have unique properties that make them nearly ideal as radioactive tracers for in vivo metabolic studies. Using positron emission tomographic (PET) scanning and positron-labeled radiopharmaceuticals, one can study local glucose metabolism in tissues, blood flow, oxygen utilization, protein synthesis, and many other functions noninvasively in normal subjects and patients who have various diseases. A review of some of these techniques and the relative advantages and problems associated with the PET approach is presented.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Cerebral Angiography In Posterior Fossa Revascularization, Roushdy S. Boulos, Suresh Patel, Bharat Mehta, Clifford Jack

Henry Ford Hospital Medical Journal

With advances in microsurgical techniques and refinement of cerebral angiography, many new surgical approaches for the treatment of vertebrobasilar insufficiency (VBI) have been developed. Detailed selective cerebral angiography is essential for confirming the clinical diagnosis, for demonstrating the exact anatomical and topographical vascular pathology, and for deciding on the best surgical procedure. Angiography is recommended to evaluate treated patients both in the early and late postoperative periods. It is an essential element of any future randomized study to assess the value of surgical vs medical treatment of patients with VBI. The benefits of cerebral angiography far outweigh the small risk …

Digital Radiography: A Review, David J. Kastan, Laurens V. Ackerman, Peter J. Feczko, Gordon H. Beute

Henry Ford Hospital Medical Journal

The fully digital radiology department remains a radiologist's dream. The technology necessary for implementation does not yet exist other than in prototype form. When the technology catches up with the radiologist's ideas, many new capabilities will exist. Electronically stored images will be available for viewing wherever a computer terminal exists. The problem of film loss would be nonexistent. Images could be quickly transmitted for interpretation via microwave networks to sites far removed from where they are acquired. Patient radiation exposure would decrease. Computers would help decrease perception errors and would assist in image interpretation. It may be ten years before …

Preliminary Experience With Digital Subtraction Angiography In Cardiac Evaluation, Matthew W. Burke, P. C. Shetty, Rajinder Sharma, James F. Brymer, Fareed Khaja

Henry Ford Hospital Medical Journal

iVe report our initial experience using digital subtraction angiography (DSA) techniques for cardiac evaluation. DSA of the heart may be performed with intravenous or right atrial injection of contrast medium (IVDSA) and with left ventricular or aortic root contrast injection (lADSA). The right ventricle and the atria are best demonstrated by IVDSA, while the left ventricle and coronary arteries are best demonstrated by lADSA. The advantages and disadvantages of DSA ofthe bean are discussed. Present equipment limitations restrict the routine use of cardiac DSA, but these should be overcome with advances in technology.

Nuclear Magnetic Resonance: Current And Future Clinical Applications, Jerry W. Froelich, David O. Hearshen, Robert D. Halpert, Suresh Patel

Henry Ford Hospital Medical Journal

Nuclear magnetic resonance has evolved from a laboratory analytical tool to become a rapidly developing discipline in clinical medicine. We present a brief historical overview, an introduction to the basic principles of the phenomenon, and a statement of the current status of clinical imaging. We have elected to use the traditional terminology nuclear magnetic resonance to refer to the imaging component of the field rather than the American College of Radiology (ACR) modification magnetic resonance. We do this out of respect for the founders of the field.

Stability In Mechanical Expansion Of The Maxilla With Surgical/Mechanical Expansion Of The Mandible In An Adult Baboon, Robert D. Mitchell

Loma Linda University Electronic Theses, Dissertations & Projects

Expansion of the maxilla at the midpalatal suture has had much investigation and is a recognized option in orthodontic therapy. Lateral expansions of the mandible through surgical separation at the symphysis have been done in animal studies. A combination of these procedures has not yet been done together.

The purpose of this study was to expand both the maxilla and the mandible of a baboon simultaneously while maintaining occlusion. The amount of expansion and stability was studied using photographs, models, cephalograms, and tetracycline bone labels using U.V. microscopy.

A young adult baboon with full dentition and normal occlusion was used. …

Predictive Value Of Radiographic Analysis Of Menton, Hyoid Bone, And The Third Cervical Vertebra Angle, Kalfred G.S. Chun

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study is to determine if the hyoid bone could be used as a reliable and stable reference landmark. Previous researchers have used cranial landmarks to determine the hyoid bone position. The results of these studies have shown a large variability in hyoid position. To determine the hyoid bone position, an analysis called the hyoid triangle was used. The hyoid triangle is formed by joining the cephalometric points retrognathion (the most inferior posterior point on the mandibular symphysis), hyoidale (the most superior anterior point on the body of the hyoid bone), and C3 (the most anterior inferior …

The Effects Of Blood Glucose Self-Monitoring On Self-Esteem And The Ability To Apply Knowledge About Diabetes Mellitus, Nancy-Lu F. Moul

Ellmer School of Nursing Theses & Dissertations

This study explored the effect of blood glucose self-monitoring on two dependent variables: (a) the diabetic client's self-esteem, and (b) the diabetic client's ability to apply knowledge about diabetes mellitus. The sample consisted of two groups of adult Type I diabetic clients. Group I consisted of ten clients who had been performing blood glucose self-monitoring for at least one year, and group II consisted of ten clients who had been performing urine testing for at least one year. A questionnaire was utilized which included: (a) a demographic data sheet, (b) a diabetic knowledge tool, and (c) a self-esteem tool. The …

Digest Of The Philadelphia College Of Osteopathic Medicine (Spring 1985), Philadelphia College Of Osteopathic Medicine

Digest

The Spring 1985 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• The President's Page
• The 94th Commencement
• Commencement Photos
• Master of Science Degrees Conferred
• Commencement Award Winners
• Families
• The Class of 1985 and Internship Hospitals
• Faculty Notes
• New Appointments
• News from the OMCP
• From the Alumni Office
• Alumni News Briefs
• Nurses Alumnae Biennial Banquet
• In Memoriam
• Coming Events

The Strange Story Of Jay Mclean, The Discoverer Of Heparin, Conrad R. Lam

Henry Ford Hospital Medical Journal

Since 1939, the use of heparin has become widespread in the prevention of postoperative thrombosis and embolism and is the basis for modern open-heart surgery. What is not generally known is the story of Jay McLean, the second-year medical student at Johns Hopkins who is given credit for the original discovery. McLean's first scientific publication concerning the use of heparin does not contain the word "heparin," and not until 25 years later did McLean publish a short paper about heparin. Some personal letters and other research have indicated a checkered career. He was trained as a surgeon in the Halsted …

Central Pontine Myelinolysis In A Patient With Adrenal Insufficiency, John E. Brunner

Henry Ford Hospital Medical Journal

Central pontine myelinolysis is a demyelinating process that has occurred in association with rapid correction of hyponatremia. Presented here is the case of a patient who had adrenal insufficiency and who experienced signs of central pontine myelinolysis after rapid correction of severe hyponatremia (28 mEq/L of sodium administered in the first 24 hours, initial serum sodium level 97mEq/L). Sustained hyponatremia and the use of intravenous contrast material after hyponatremia correction are discussed as possible risk factors in the development of central pontine myelinolysis.

In Defense Of The Pickwickian Syndrome, Howard Markel

Henry Ford Hospital Medical Journal

No abstract provided.

Diagnosis Of Hepatic Portal Venous Gas By Computed Tomography: Role Of Intravenous Contrast Material, Allan M. Haggar, Michael A. Sandler, Martin L. Gross, Beatrice L. Madrazo

Henry Ford Hospital Medical Journal

We describe a case of hepatic portal venous (HPV) gas. The diagnosis was assisted by findings of computed tomography (CT). The HPV gas resulted from a diverticular abscess in a patient who had a stable clinical course. If the possibility of HPV gas exists, scanning without intravenous administration of contrast material should be performed. If postcontrast scans alone are obtained, the opacified portal blood may mask small amounts of HPV gas, as was true in this case. Also, postcontrast scans can easily distinguish HPV gas from air within the biliary tree if findings of precontrast scans are equivocal.

The Invalidity Of Monitoring Transcutaneous Oxygen Tension In Patients Who Have Chronic Renal Failure, John R. Armstrong, Thomas W. Kreps, William A. Conway, Francis Dumler, John Popovich Jr.

Henry Ford Hospital Medical Journal

We assessed accuracy of monitoring transcutaneous oxygen tension (PtcO2) in patients with chronic renal failure (CRF). Sixteen stable individuals undergoing chronic maintenance hemodialysis were studied. Correlations between simultaneously determined PtcO2 and arterial oxygen tension (PaO2) were made both before and during dialysis. Comparisons were made with a group of 22 consecutive patients in whom respiration was mechanically assisted, who were hemodynamically stable (urine output greater than 30 mL/hour, pulse less than 130 beats/min, and mean arterial blood pressure greater than 80 mm Hg in the absence of pressor agents), and who had normal renal function.

Among CRF patients, the correlation …

Editorial: In Defense Of Historians, Conrad R. Lam

Henry Ford Hospital Medical Journal

No abstract provided.

Unprovoked Seizures And Myoclonus In Patients With Alzheimer's Disease, Marcia L. Morris

Journal of the Minnesota Academy of Science

Although anecdotal references commonly presume that seizures eventually occur in patients affected with dementia of the Alzheimer type (DAT), no previous American study has documented the rate of new onset, unprovoked seizures in DAT patients. There are few documented cases of the occurrence of myoclonus in autopsy-proven DAT. In a series of 83 autopsy-proven DAT cases, medical records were scrutinized for the presence of any seizure or myoclonic activity. Final evaluations were made by a neurologist. Of the 83 cases, 8 had experienced one or more unprovoked seizures after the onset of DAT. Based on age-specific incidence rates from a …

Triage: Endgame Realities, George P. Smith Ii

Scholarly Articles

No abstract provided.

Oncolog, Volume 30, Number 03, July-September 1985, Fernando F. Cabanillas Md

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Natural Killer Cells: Research Shows They Are Early Destroyers of Malignancy
• Better Classification and New Drug Regimens Have Advanced Treatment for Lymphoid Cancer
• Rural Science Park is Laboratory for Basic Work on Carcinogenesis
• New Book: Candidiasis

Linkage Data Excluding A Locus For Multiple Endocrine Neoplasia Type 2 Syndromes From The Distal Part Of The Short Arm Of Chromosome 11, Kenneth K. Kidd, Susan D. Kruger, Daniela S. Gerhard, Judith R. Kidd, David Housman, Joseph M. Gertner

Henry Ford Hospital Medical Journal

A study designed to identify the location of a gene for multiple endocrine neoplasia type 2 (MEN-2) is being performed using a single large family segregating for MEN-2A. Here we report our initial results using a set of DNA restriction fragment length polymorphisms spanning a 40 cM segment of the short arm of human chromosome 11. The locus for MEN-2 in this family is excluded from this entire region which includes an oncogene, c-Ha-ras-1, two hormone loci, insulin and parathyroid, and the five hemoglobin genes in the beta hemoglobin gene duster. This is the first exclusion of such a large …

Multiple Endocrine Neoplasia Type 2 Syndromes: Historical Perspectives, John H. Sipple

Henry Ford Hospital Medical Journal

No abstract provided.

Screening For Hereditary Medullary Cancer In Denmark, Kristian Emmertsen

Henry Ford Hospital Medical Journal

Screening of first-degree relatives of patients with medullary thyroid cancer (MTC) gave normal values of pentagastrin-stimulated serum calcitonin and 24-hour urinary catecholamine levels in the relatives of 18 of 22 patients. This result is considered to be valid evidence for sporadic MTC. Absence of C-cell hyperplasia maybe another indication of sporadic MTC. Four hereditary MTCs were represented by one fully expressed MEN-2B patient without affected relatives, one fully expressed MEN-2A case in one family, and two first cousins with MTC as the only MEN-2A lesion in another family. Fourteen relatives of the MEN-2A patients had elevated serum calcitonin levels, and …

A French Canadian Family With Multiple Endocrine Neoplasia Type 2 Syndromes, Maurice B. Verdy, Marcel Cadotte, Walter Schurch, William C. Sturtridge, Jacques Cantin, Andrée M. Weber, André Lacroix, Cynthia Forster-Gibson

Henry Ford Hospital Medical Journal

No abstract provided.

Genetic Studies Of Multiple Endocrine Neoplasia Type 2 Syndromes: A Workshop Commentary, Nancy E. Simpson

Henry Ford Hospital Medical Journal

No abstract provided.

Digest Of The Philadelphia College Of Osteopathic Medicine (Winter 1984-1985), Philadelphia College Of Osteopathic Medicine

Digest

The Winter 1984-1985 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Founders Day/ Alumni Weekend
• Portrait of a President
• Highlights of Founders Day/Alumni Weekend
• Galen S. Young, Sr., DO
• Reunions and Reminiscences
• Sherman Leis, DO
• News from the OMCP
• News from the Alumni Office
• Faculty Notes
• Alumni News Briefs
• In Memoriam
• Coming Events