Digital Commons Network^™

Cost Of Acute Stroke Care At A Tertiary Care Hospital In Karachi, Pakistan, B. A. Khealani, Z. F. Javed, N. A. Syed, Saad Shafqat, Mohammad Wasay

Section of Neurology

Objective:To evaluate cost of acute stroke care and its determinants at a tertiary care hospital in Karachi and to find out predictors of high cost care. Acute stroke is a leading cause of morbidity and mortality. Cost of care is the single most important determinant in availability of acute stroke care at a tertiary care hospital in Pakistan.It is also an important factor in development of public health policies and medical insurance plans. Average nnual income in Pakistan is 4881 rupees (U$ 85).
Methods: Medical and billing records of 443 patients with acute stroke were retrospectively reviewed from …

Clarifying The Lower Incidence Of Birth Defects In The Midwest Of Western Australia : A Study Using Capture Re-Capture Methodology, Donna Baker

Theses: Doctorates and Masters

In April 2000 the Western Australian Birth Defects Registry held its 20th Anniversary Scientific Symposium to signify the first 20 years of the Birth Defects Registry in Western Australia. At the Symposium, significant trends and occurrences in birth defects within Western Australia over the past 20 years were addressed. One factor highlighted in the Registry's 1980-1999 report was that birth defects were reported less frequently in rural regions compared with metropolitan areas. Data collected from the metropolitan area is considered by the Birth Defects Registry to be the most accurate. Therefore, incidence rates of birth defects in this area arc …

Storying The Body : Women's Narratives Through The Lens Of Breast Cancer, Janet A. Griffin

Theses : Honours

What can women's narratives contribute to our understanding of breast cancer and to feminist theories of the body? This thesis explores the meanings women construct to make sense of embodied experiences of breast cancer, and the profound experience of breast loss. Rich contextual data was elicited from in depth, guided conversations with five premenopausal women who have undergone mastectomy. Adopting feminist methodology, biographic-narrative was used to place the body at the heart of inquiry. This thesis explores the personal and theoretical meanings of mastectomy, embedded in the larger story of how these five women experience their breasts, throughout their lives. …

Febrile Seizures: Factors Affecting Risk Of Recurrence In Pakistani Children Presenting At The Aga Khan University Hospital, Z Habib, S Akram, S Ibrahim, B Hasan

Department of Paediatrics and Child Health

Objectives: To (a) describe the effect of temperature rise on seizure recurrence in the ER (b) investigate the effect of age, gender, family and developmental history, type, duration and multiple seizures, past history and number of seizures and treatment given (either late or early) on seizure recurrence in the ER and (c) explore prognostic indicators for seizure recurrence.
Methods: Data from 352 children [ages 3-84 months; 220 males (62.5%) 132 females (37.5%)] was taken using chart reviews for the years January 1998-August 2000 inclusive, from the Pediatric department of the Aga Khan University Hospital. Descriptive statistics, Chi-square, and Discriminant …

Fall Risk Assessment : A Prospective Investigation Of Nurses' Clinical Judgement And Risk Assessment Tools In Predicting Patient Falls In An Acute Care Setting, Helen Myers

Theses: Doctorates and Masters

Falls are a significant problem in acute care, hospital settings, and can have serious consequences, especially for older patients. Fall prevention has therefore been recognised as an important area for research and intervention. In order to target interventions and use resources effectively, a major strategy of many fall prevention programmes has been the development and/or use of risk assessment tools to identify patients who are at high risk of falling. Although many tools have been developed, few have been rigorously tested, and there is currently no evidence to support the clinical utility of fall risk assessment tools. There is a …

L’Observation Du Comportement Du Nouveau-Ne: Une Source Pertinente D’Informations Medicales, N. Ratynski, G. Cioni, L. Franck, Yvette Blanchard, J. Sizun

All PTHMS Faculty Publications

L’observation du comportement du nouveau-né est une source importante d’informations d’ordre médical. Trois domaines bénéficient des données de l’observation : 1) l’analyse du développement grâce à l’utilisation de l’Assessment of Preterm Infant Behavior (évaluation du comportement de l’enfant prématuré) ; 2) l’évaluation de la douleur dominée par l’analyse de l’expression faciale grâce à des échelles validées, telle que le Neonatal Facial Coding System (système néonatal de codage facial) ; 3) la recherche de lésions cérébrales par le Quality Assessment of General Movements (évaluation de la qualité des mouvements généraux). L’observation comportementale fondée sur des outils validés par la recherche …

An Investigation Of Perceived Restrictions On Certified Athletic Trainers Practice, Katy Taake

All-Inclusive List of Electronic Theses and Dissertations

The purpose of this study was to identify the frequency and nature of perceived restrictions by certified athletic trainers (ATCs) and to determine the frequency of perceived restrictions for each practice setting within states that have legislation. This was a qualitative-descriptive study performed with a web-based survey. 10,000 ATCs receiving electronic mail from the National Athletic Trainers' Association (NATA) were invited to participate in this study. 1158 subjects participated in the study, and 724 subjects (295 female and 429 male; age=33.2 ± 8.3yrs) remained after exclusions. A webbased survey was created to evaluate perceived restrictions. Inorder to establish face validity …

Com Outlook Fall 2002, College Of Osteopathic Medicine

COM Outlook

No abstract provided.

Medical Education Digest, Vol. 4 No. 5 (September 15, 2002), Nova Southeastern University

Medical Education Digest

No abstract provided.

Comparative Study--Efficacy, Safety And Compliance Of Intravenous Iron Sucrose And Intramuscular Iron Sorbitol In Iron Deficiency Anemia Of Pregnancy, A Wali, A Mushtaq, Nilofer

Department of Obstetrics & Gynaecology

Objective: (1) To determine an alternative iron supplementation with better efficacy, compliance & safety in treatment of iron deficiency anemia during pregnancy, (2) to reduce blood transfusion during pregnancy, labor and puerperium.
Material and Method: A prospective comparative study. A total number of 60 pregnant women with the gestational age of 12 - 34 weeks were included in the study who were suffering from iron deficiency anemia. They were divided in 3 groups (A, B and C). Group A (n15) received intravenous iron sucrose according to recommended dose containing 500 mg of iron sucrose for storage, in group B (n=20) …

Linder-Aronson S Analysis Using Rhinomanometry And Newtom, Noel Moser

Loma Linda University Electronic Theses, Dissertations & Projects

Investigations into the effects of airway patency on craniofacial development are essential to ensure that interceptive orthodontic treatment provides the maximum benefit to the patient. The aims of this study were to (1) compare the size of the nasopharyngeal airway space on lateral cephalometric and 3D volumetric radiographs to determine if volumetric scans can be of greater diagnostic value than a lateral cephalometric film in determining the degree of airway blockage or patency and (2) to examine the correlation between functional airway resistance, as evaluated by rhinomanometry, and radiographic constriction due to nasal turbinate and adenoid size.

Twenty-eight subjects from …

Comparative Methods Of Measurement To Evaluate Onplant Assisted Anchorage, Marc Reid Larson

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to compare the two-dimensional cephalometric and the three-dimensional tomographic radiographic methods in their ability to assess anatomic measurements while using the Onplant anchoring device in anterior retraction cases.

The Onplant was surgically placed beneath the periosteum of the hard palate. After osseointegration the Onplant was then uncovered and attached to the first molars by means of a transpalatal bar. Conventional orthodontic treatment was then used to retract the anterior teeth after 1^st premolars were extracted.

To evaluate the movement of the Onplant, a three-dimensional measuring tool was needed. Seven different measurements were made …

Regulation Of Retinoic Acid Receptor Α By Protein Kinase C In B16 Mouse Melanoma Cells, Goran Boskovic, Dinakar Desai, Richard M. Niles

Biochemistry and Microbiology

We have previously found that retinoic acid stimulates the expression of protein kinase Cα (PKC) in B16 mouse melanoma cells. Because it has been reported that PKC can phosphorylate retinoic acid receptor (RAR) and alter its function, we determined whether changes in the level and/or activity of PKC could affect the expression or function of the RAR in B16 melanoma. Using in vivophosphorylation and band shift techniques, we could not demonstrate that altering PKC activity and/or protein level changed thein vivo phosphorylation of RARα. However activation of PKC resulted in increased RARα protein. Increased receptor protein correlated with …

Justification For The Continuance Of A Pediatric Physician's Office Laboratory, Veronica C. Santilli

Seton Hall University Dissertations and Theses (ETDs)

The continued viability of the Physician's Office Laboratory (POL) has been questioned because of barriers imposed by managed care organizations, oversight by regulatory agencies and competition for professionally trained laboratory staff. Pediatricians view the POL as an important adjunct to quality healthcare services for children and do not consider the POL as a "profit center", whose priority is generation of revenues for the The practice. parents of pediatric patients consider an on-site laboratory a convenience and valuable service. Through an analysis of patients' satisfaction, physicians' perceptions of enhancement to quality care, managed care reimbursement data and costs associated with maintenance …

Com Outlook Summer 2002, College Of Osteopathic Medicine

COM Outlook

No abstract provided.

Role Of Signal-Averaged Ecg In Predicting Results Of Flecainide Provocation Test Used In Family Screening For Brugada Syndrome, Ngai-Shing Mok, Chi-Chung Choy, Ngai-Yin Chan, Amy Ho

Journal of the Hong Kong College of Cardiology

Brugada syndrome (BS) is an inherited arrhythmogenic disease with an autosomal dominant mode of inheritance. Flecainide provocation test (FPT) has been shown to be highly sensitive and specific in unmasking the Brugada ECG pattern in affected subjects. We sought to test if late potential (LP) in signal averaged electrocardiogram (SAECG) is helpful in predicting the results of FPT used in family screening for BS. The study included 17 asymptomatic Chinese subjects from 8 families (M:F 10:7, mean age 24.8±11.4 years) who have undergone family screening for BS. All screened subjects had a normal 12-lead ECG at baseline. None had structural …

Use Of An Anaerobic Chamber Environment For The Assay Of Endogenous Cellular Protein-Tyrosine Phosphatase Activities., Li Zhu, Barry Goldstein

Department of Medicine Faculty Papers

Protein-tyrosine phosphatases (PTPases) have a catalytic cysteine residue whose reduced state is integral to the reaction mechanism. Since exposure to air can artifactually oxidize this highly reactive thiol, PTPase assays have typically used potent reducing agents to reactivate the enzymes present; however, this approach does not allow for the measurement of the endogenous PTPase activity directly isolated from the in vivo cellular environment. Here we provide a method for using an anaerobic chamber to preserve the activity of the total PTPase complement in a tissue lysate or of an immunoprecipitated PTPase homolog to characterize their endogenous activation state. Comparison with …

Macular Hemorrhage Secondary To Increased Intrathoracic Pressure And Difficult Intubation, A Abbas, G Hyman

Section of Ophthalmology

No abstract provided.

Modular Machine Learning Methods For Computer-Aided Diagnosis Of Breast Cancer, Mia Kathleen Markey '94

Doctoral Dissertations

The purpose of this study was to improve breast cancer diagnosis by reducing the number of benign biopsies performed. To this end, we investigated modular and ensemble systems of machine learning methods for computer-aided diagnosis (CAD) of breast cancer. A modular system partitions the input space into smaller domains, each of which is handled by a local model. An ensemble system uses multiple models for the same cases and combines the models' predictions.

Five supervised machine learning techniques (LDA, SVM, BP-ANN, CBR, CART) were trained to predict the biopsy outcome from mammographic findings (BIRADS™) and patient age based on a …

Digest Of The Philadelphia College Of Osteopathic Medicine (Summer 2002), Philadelphia College Of Osteopathic Medicine

Digest

The Summer 2002 Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Opening Remarks
• PCOM Updates
• It's a Family Practice Affair
• Helping People Age Successfully
• Why Don't Patients Comply?
• Class Notes
• In Memoriam
• My Turn
• Andrew Taylor Still Legacy Society
• PCOM Events

Current Practice Regarding The Use Of Fatty Livers: A Trans-Atlantic Survey., Charles J. Imber, Shawn D. St Peter, Inigo Lopez, Lynden Guiver, Peter J. Friend

Manuscripts, Articles, Book Chapters and Other Papers

A strong association exists between the presence of steatosis in a donor liver for transplantation and the development of primary nonfunction in the recipient. Despite this, appraisal of the donor remains one of the least scientific aspects of the transplantation process, and many centers base their practice on subjective opinion, rather than objective data. We conducted this survey to illuminate controversial issues and highlight the variation of opinion and practice policies both between and within the United Kingdom and the United States. A simple, anonymous, one-page, 10-question survey with tick-box answers was sent to every practicing liver transplant surgeon in …

Com Outlook Summer 2004, College Of Osteopathic Medicine

COM Outlook

No abstract provided.

The Reliability Of Emg Normalization Procedures For Three Muscles Invol Ved In Knee Extension, Gerrik J. Schepel

Masters Theses

This retrospective study analyzed the three muscles involved in knee extension: vastus medialis, rectus femoris, and vastus lateralis. lt was conducted to determine the reliability of normalization procedures when evaluating the EMG response detected from a muscle. During a maximal voluntary isometric contraction {MVIC), the EMG response of the muscle was recorded and the iEMG moment per unit area was determined. The iEMG response ofthe quadriceps muscles during dynamic exercise was normalized using the MVIC. Subjects (N = 44) performed two consecutive MVICs with a 2-min rest between trials at 110°, 90°, 70°, 50°, and 30° of knee flexion, …

Role Of Disulphide Bond Formation In Folding, Secretion, And Assembly Of Human Chorionic Gonadotropin Subunits., Elliott Bedows, Ryan J. Darling, Jason A. Wilken, Simon Sherman

Journal Articles: Eppley Institute

Ability of a glycoprotein hormone to fold and assemble correctly is an essential requirement for the attainment of its biological activity . Cells have a quality control system to assure that when proteins of the endoplasmic reticulum mi sfold or fail to assemble correctly they do not exit the cell. But human chorionic gonadotropin (hCG) is an exception to this rule as is illustrated by the following observations. First, both hCG subunits are secreted efficiently as unassembled monomers. Second, some mis(un)folded forms of hCG-β can be efficiently secreted from cells that do not facilitate the secretion of other misfolded proteins. …

Mexican-Descent Latinas’ Compliance With Cervical Cancer Screening Guidelines, Evelinn A. Borrayo, Awilda Reyes

University Libraries Faculty Publications

No abstract provided.

Enhancement Of Anti-Hiv-1 Ribozyme Activities By Rev Binding And Multimerization, Yuksel Yildiz

Loma Linda University Electronic Theses, Dissertations & Projects

To effectively apply hammerhead ribozymes as therapeutic agents it is necessary to co-localize them with the desired target. Human immunodeficiency virus type1 (HIV- 1) infectivity is dependent on env gene expression. HIV-1 Rev protein binds to a higher ordered RNA structure within the env transcript termed the Rev Binding Element (RBE). In anti-HIV gene therapy employing ribozymes to increase the co-localization of anti- HIV ribozymes with target HIV mRNAs, it has been proposed that when the native HIV- 1 RBE is appended to a ribozyme as a decoy molecule, simultaneous binding of Rev monomers to the RBE sequences in both …

Medical Education Digest, Vol. 4 No. 1 (January 15, 2002), Nova Southeastern University

Medical Education Digest

No abstract provided.

Older Adults, Social Techniques, And Memory, Karla K. Ziegenbalg

Case Studies from Age in Action

Educational Objectives

1. To use a social psychological perspective to examine memory abilities of older adults.

2. To understand in what ways the social environment, through direct social interaction, affects the memory performance of older adults.

3. To find out what, if any, social factors support memory performance in older adults.

Are You At Risk For Blindness? Don't Keep Glaucoma A Family Secret! Older Age Is A Risk Factor, Mary Price

Case Studies from Age in Action

Educational Objectives

1. Raise awareness of risk factors for glaucoma.

2. Encourage health care providers to educate the patient about glaucoma risk factors.

3. Educate glaucoma patients to encourage family members to seek a glaucoma examination.

2001 Cancer Care Annual Report, Children's Mercy Hospital

Cancer Center Annual Reports

Annual report of cancer care and oncology services at the Children's Mercy Hospital, Kansas City MO, a pediatric medical center, with a focus on Wilms' Tumor.