Digital Commons Network^™

Re-Imagining The Experience And Study Of Aging, Edward F. Ansello

Director's Editorials from Age in Action

A small group of Japanese and American gerontologists have been working together toward developing a gerontology curriculum that would help people to understand the experience of aging. The group suggested adding business, information technology/communication, and education to the curriculum. The group also acknowledged that a curriculum on aging should include a way to help those of us who are not old to understand the importance for many who are old of the search for the infinite, the true self, the oneness, the spirit, or the divine, at the core of life.

Acute And Chronic Pain Challenges For Arthritis Patients In An Acute Care Setting, Janet M. Bykowski

Case Studies from Age in Action

Educational Objectives

1. Demonstrate the importance of chronic pain management in an acute care environment.

2. Discuss the special impact of co-morbidity of arthritis upon pain management intervention.

3. Provide education to clinicians, patients, and caregivers that would promote an interdisciplinary plan of care for acute and chronic concurrent pain management.

“Powerful Tools For Caregivers”: Teaching Skills That Reduce Stress And Increase Self-Confidence, Ed Rosenberg, Natasha Gouge

Case Studies from Age in Action

Educational Objectives

1. Describe caregiving stress and burnout symptoms and effects experienced by older caregivers.

2. Report implementation and evaluation of the “Powerful Tools for Caregivers” workshop, which is designed to increase knowledge and skills in caring for elders and reduce caregiver stress.

3. Suggest ways to alleviate caregiver burden at both micro and macro levels.

Teens Teaching Alzheimer’S Caregivers To Become Tech- Savvy: The Power Of Community And Intergenerational Partnerships, Ann Bruner Duesing, Marilyn Pace Maxwell

Case Studies from Age in Action

Educational Objectives

1. Describe a successful technology project for Alzheimer’s caregivers in rural, far southwest Virginia which recruited and trained teenagers to teach computer skills to Alzheimer’s caregivers and taught the teenagers about caregiving and the disease.

2. Identify barriers for Alzheimer’s caregivers to learning and using technology to assist and support them in their caregiving, and identify successful ways to address these barriers.

Health Professions Division Catalog 2007-2008, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

2006 Cancer Care Annual Report, Children's Mercy Hospital

Cancer Center Annual Reports

Annual report of cancer care and oncology services at the Children's Mercy Hospital, Kansas City MO, a pediatric medical center. This report has a focus on tumors of the central nervous system.

Effects Of Retinoic Acid On Beta-Catenin Transcriptional Activity In Melanoma Cells, Fung Chan

Theses, Dissertations and Capstones

Melanoma is the most dangerous form of skin cancer and its incidence has been increasing in the United States. Most melanomas are resistant to current chemotherapies; therefore, understanding the mechanism of melanomagenesis is beneficial to treatment of the diseases. Accumulation of β-catenin has been shown in colon and other cancers, including melanomas, but the transcriptional role of β-catenin in melanomas is still unclear. All-trans retinoic acid (ATRA) is an anti-tumor agent that has an inhibitory effect on β-catenin, but this effect has not been studied in melanomas. It has been shown that Microphthalmia-associated transcription factor (MITF), a melanocyte specific protein, …

Modulation Of Radiation Responses By Pre-Exposure To Irradiated Cell Conditioned Medium, Paula Maguire, Carmel Mothersill, B. Mcclean, C. Seymour, Fiona Lyng

Articles

The aim of this study was to investigate whether exposure of HPV-G cells to irradiated cell conditioned medium (ICCM) could induce an adaptive response if the cells were subsequently challenged with a higher ICCM dose. Clonogenic survival and major steps in the cascade leading to apoptosis, such as calcium influx and loss of mitochondrial membrane potential, were examined to determine whether these events could be modified by giving a priming dose of ICCM before the challenge dose. Clonogenic survival data indicated an ICCMinduced adaptive response in HPV-G cells ‘‘primed’’ with 5 mGy or 0.5 Gy ICCM for 24 h and …

Department Of Radiology-Annual Executive Summary Report-July 1, 2006 To June 30, 2007, Vijay M. Rao M.D.

Department of Radiology Administrative Documents and Reports

91 page Department of Radiology Annual Executive Summary Report, July 1, 2006 to June 30, 2007, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States.

Masters Of Public Health 2007, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Children's Mercy Hospital Annual Report 2006, Children's Mercy Hospital

Children's Mercy Annual Reports

Annual report for The Children's Mercy Hospital in Kansas City MO, a pediatric medical center.

The Use Of Telehealth For Diabetes Management: A Qualitative Study Of Telehealth Provider Perceptions, Faith P. Hopp, Mary M. Hogan, Peter A. Woodbridge, Julie C. Lowery

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Monitoring and Messaging Devices (MMDs) are telehealth systems used by patients in their homes, and are designed to promote patient self-management, patient education, and clinical monitoring and follow-up activities. Although these systems have been widely promoted by health care systems, including the Veterans Health Administration, very little information is available on factors that facilitate use of the MMD system, or on barriers to use.

Methods

We conducted in-depth qualitative interviews with clinicians using MMD-based telehealth programs at two Veterans Affairs Medical Centers in the Midwestern United States.

Results

Findings suggest that MMD program enrollment is limited by both …

Progression Of Renal Cell Carcinoma Is Inhibited By Genistein And Radiation In An Orthotopic Model, Gilda G. Hillman, Yu Wang, Mingxin Che, Julian J. Raffoul, Mark Yudelev, Omer Kucuk, Fazlul H. Sarkar

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

We have previously reported the potentiation of radiotherapy by the soy isoflavone genistein for prostate cancer using prostate tumor cells in vitro and orthotopic prostate tumor models in vivo. However, when genistein was used as single therapy in animal models, it promoted metastasis to regional para-aortic lymph nodes. To clarify whether these intriguing adverse effects of genistein are intrinsic to the orthotopic prostate tumor model, or these results could also be recapitulated in another model, we used the orthotopic metastatic KCI-18 renal cell carcinoma (RCC) model established in our laboratory.

Methods

The KCI-18 RCC cell line was generated …

Reducing Lung Disease In Cystic Fibrosis: Model Systems And Anti-Inflammatory Treatment, Scotty Mcglothlin Buff

MUSC Theses and Dissertations

Cystic fibrosis (CF), the most common lethal autosomal recessive disease in Caucasians resulting in a median life span of approximately 35 years, is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR). The primary cause of morbidity and mortality is respiratory failure caused by progressive obstructive lung disease. CF airway disease is characterized by the abundance of pro inflammatory cells, chemokines and cytokines with a deficiency of regulatory/anti-inflammatory cytokine interleukin 10 (lL10). We hypothesized that CF airway obstruction originates from excessive inflammation and gene transfer of IL-I0 would decrease inflammation in the airways of mice infected with Pseudomonas …

Mapping Exercise Of Mental Health Research And Researchers In Pakistan, Haider A. Naqvi, Murad M. Khan

Department of Psychiatry

Objective: To systematically identify mental health research and researchers in Pakistan. Subsidiary objectives were to identify methodologies of studies published in the indexed journals along with their country wide mean impact factor.
Methods: A systematic search strategy using key words related to neuropsychiatry was carried out to identify various studies published in Indexed and Non-indexed databases.
Results: We identified 108 studies from Indexed data bases (77.8% Medline; 22.2% PsychInfo). Beside these, 51 studies were also identified from non-indexed databases. Among the indexed articles, 97 (89.8%) were Journal articles while 10 were other type of documents--there were 3 clinical trials of …

The Status Of Childhood Lead Poisoning And Prevention In Nevada, Usa, Anne Rothweiler, Elena E. Cabb, Shawn Gerstenberger

Environmental & Global Health Faculty Research

One of the first steps in addressing the problem of childhood lead poisoning is to identify the possible sources of exposure in specific communities and target high-risk populations with appropriate interventions. Due to several factors, such as lack of funding and lack of blood lead reporting, little information exists regarding the occurrence of childhood lead poisoning and the prevalence of potential exposure sources in the state of Nevada. Following the recent establishment of a Nevada-based Lead Poisoning Program, we compiled the most current information available on Nevadans, and use this knowledge to suggest future research objectives and outreach activities for …

A Non-Pharmacological Intervention To Manage Behavioral And Psychological Symptoms Of Dementia And Reduce Caregiver Distress: Design And Methods Of Project Act3., Laura N Gitlin, Laraine Winter, Marie P Dennis, Walter W Hauck

Center for Applied Research on Aging and Health Research Papers

Project ACT is a randomized controlled trial designed to test the effectiveness of a non-pharmacological home-based intervention to reduce behavioral and psychological symptoms of dementia (BPSD) and caregiver distress. The study targets 272 stressed racially diverse family caregivers providing in-home care to persons with moderate stage dementia with one or more behavioral disturbances. All participants are interviewed at baseline, 4-months (main trial endpoint), and 6-months (maintenance). The four-month intervention involves up to 13 visits from an occupational therapist who works with families to problem-solve potential triggers (communication style, environmental clutter) contributing to behaviors, and instruct in strategies to reduce caregiver …

Pulmonary Artery Catheter Knotting In A Coronary Artery Bypass Surgery Patient, Mohammad Irfan Akhtar, Mohammad Hamid, Fazal Hameed Khan, Hamid Iqil Naqvi, Amar Gangwani

Department of Anaesthesia

A fifty seven years old female patient came to operating room for coronary artery bypass grafting (CABG) surgery. After induction, invasive monitoring lines were placed. Pulmonary artery catheter (PAC) floated after three attempts and it was wedged at 60cm. Intra operative course was smooth and patient transferred to cardiac intensive care unit (CICU). First chest X-ray revealed PAC knotting in the right ventricle. Vascular surgeon was involved and he removed it through right internal jugular vein under fluoroscopic guidance. Pulmonary arterial catheterization is an invasive procedure. Knotting usually occurs due to excessive advancement of the pulmonary artery catheter beyond the …

Oncolog, Volume 52, Number 12, December 2007, Sunni Hosemann, Diane Witter, Huong Le-Petross Md

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Worth More than a Thousand Words\
• A Step Forward for Stents
• House Call: Getting the Most From Your Doctor Visit
• DiaLog: Is MRI Better for Breast Screening?, by Huong Le-Petross, MD

Oncolog, Volume 52, Number 07/08, July/August 2007, Diane Witter, Vickie J. Williams, Dawn Chalaire

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Harnessing the Power of Protons
• Gene-Environment Interaction Studies Answer the Question, “Why Did I Get Cancer?”
• House Call: Parents: Be Hopeful and Honest When Telling Kids about Your Serious Illness
• Helping Physicians Help Patients

Digest Of The Philadelphia College Of Osteopathic Medicine (Winter 2007), Philadelphia College Of Osteopathic Medicine

Digest

The Winter 2007 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Opening Remarks
• Remembering Harry Ginsburg, DO ’42
• PCOM Updates and Kudos
• Building Partnerships: Assessing the Value of Physician-Patient Communications
• Recognizing Leadership, Loyalty, Service: Founders’ Day 2007
• Places, Camera, Action . . . Learning Primary Care Skills
• Out of Africa: True Tales of a Medical Missionary
• Class Notes
• In Memoriam
• My Turn
• PCOM Events

Pediatricians' Attitudes, Experience And Referral Patterns Regarding Complementary/Alternative Medicine: A National Survey, Anju Sawni, Ronald Thomas

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

To assess pediatricians' attitudes toward & practice of Complementary/Alternative Medicine (CAM) including their knowledge, experience, & referral patterns for CAM therapies.

Methods

An anonymous, self-report, 27-item questionnaire was mailed nationally to fellows of the American Academy of Pediatrics in July 2004.

648 of 3500 pediatricians' surveyed responded (18%).

Results

The median age ranged from 46–59 yrs; 52% female, 81% Caucasian, 71% generalists, & 85% trained in the US. Over 96% of pediatricians' responding believed their patients were using CAM. Discussions of CAM use were initiated by the family (70%) & only 37% of pediatricians asked about CAM use …

Building Blocks For The Development Of A Chronic Care Lung Cancer Model, Leeanne Berlinsky

MUSC Theses and Dissertations

Lung cancer, is the leading cause of cancer death in the United States for both men and women, and as such, represents a tremendous burden on the healthcare system. Survival rates have remained relatively unchanged over the past forty years, yet we seem to be on the verge of a paradigm shift as a result of advances in early screening, diagnosis and better treatment modalities. Lung cancer is different from all other cancers in that 90% of lung cancer cases can be attributed to the conscious behavioral risk factor of smoking, either currently or previously engaged in by the patient. …

Study Of The Effectiveness Of Training Malian Social And Health Agents In Female Genital Cutting Issues And In Educating Their Clients, Nafissatou J. Diop, Fatoumata Traore, Habibatou Diallo, Ousmane Traore, Aissa Haidara Toure, Youssouf Diallo, Madina Sangare, Fatoumata Tandia, Keita Attaher Toure

Reproductive Health

This report documents findings of a study to assess the education and training of social and healthcare workers in Mali regarding female genital cutting (FGC). After two decades of campaigning against FGC in Mali, the results are not satisfactory when compared to the levels of human and financial investment. The Mali Division of Family and Community Health, with technical support from the Population Council, conducted this research to highlight certain issues related to the practice of FGC in Mali, in particular health consequences and the role health personnel can play in eradicating the practice. The continued prevalence of FGC among …

Contributing Towards Efforts To Abandon Female Genital Mutilation/Cutting In Kenya: A Situation Analysis, Humphres Evelia, Maryam Sheikh Abdi, Carolyne Njue, Ian Askew

Reproductive Health

The Kenyan Ministry of Gender, Sports, Culture and Social Services, with support from UNFPA/Kenya, commissioned the Population Council to conduct a situation analysis of female genital mutilation/cutting (FGM/C) programs in Kenya, with the overall objective of documenting the current status of and trends in FGM/C programming and to help identify crucial elements that need to be prioritized for support. Results show marked declines in prevalence nationally between generations, suggesting a decline in the practice as well as trends toward “medicalization” in recent years. The practice still continues for different reasons, such as rite of passage, for marriageability, controlling sexuality, religious …

Development Of A Blood Test For The Detection Of Cutaneous Malignant Melanoma, Rebecca Slattery

Theses : Honours

Cutaneous Malignant Melanoma is a highly aggressive form of skin cancer that has a tendency to metastasise. In its early stages, the 5-year survival rate of patients is greater than 90% following surgical excision of an in situ tumour. However, following metastasis of the tumour, the 5-year survival rate declines to 5-35%. Due to the correlation between metastasis and declining survival, studies have attempted to identify potential metastasis as early as possible. Molecular markers of melanoma cells in the peripheral blood of CMM patients have been investigated, as the invasion of tumour cells into the blood is one of the …

Is It Time To Redesign Hospice? End-Of-Life Care At The User Interface, David J. Casarett

Center for Policy Research

Hospice is a system of end-of-life care that’s not used to its full potential. That is, hospice is not used in the way that would benefit patients and families as much as it could. My argument is that this is an issue of usability, or ergonomics—the science of design. I illustrate how to take what we have learned from the science of usability to make hospice more accessible and approachable, and to increase hospice use among those who would benefit from it. Underneath this discussion, though, there is a more fundamental question: Can we make hospice more usable or do …

Knowledge, Attitude And Practice Regarding Immunization Among Family Practice Patients, Waris Qidwai, Syed Sohail Ali, Semi Ayub, Salma Ayub

Department of Family Medicine

Objective: To determine the knowledge, attitude and practices about immunization among family practice patients.
Design: A questionnaire based survey.
Patients and Method: A questionnaire was developed in line with the study objectives. It was administered to patients visiting family physicians, after they were administered, informed consent and assurance with regards to confidentiality was provided. Epi-info and SPSS software was used for data management.
Results: A total of 97 patients were surveyed. The majority were men (59.8%) with a mean age of 29.69 years. Majority was unmarried (51.5%), with graduate and post-graduate education (73%), and in government and …

Metabolic Syndrome: Frequency And Gender Differences At An Out - Patient Clinic, Firdous Jahan, Riaz Qureshi, Tasneem Borhany, Hasan Bin Hamza

Department of Family Medicine

Objective: To determine the frequency of metabolic syndrome among patients attending an out-patient clinic of a teaching hospital and to compare the clinical features regarding metabolic syndrome among males and females.
Study Design: Cross-sectional study.
Place and Duration: Aga Khan University Hospital (AKUH), Executive and Family Medicine Clinics, from December 2004 to April 2005.
Patients and Methods: All adults, above 25 years, attending the clinics for an executive check-up and giving informed consent were included in the study. Data was collected through a structured questionnaire administered to those eligible to participate. Metabolic syndrome was defined according to ATP-III guidelines. …

A Turner Syndrome Neurocognitive Phenotype Maps To Xp22.3., Andrew R Zinn, David Roeltgen, Gerry Stefanatos, Purita Ramos, Frederick F Elder, Harvey Kushner, Karen Kowal, Judith L Ross

Department of Pediatrics Faculty Papers

BACKGROUND: Turner syndrome (TS) is associated with a neurocognitive phenotype that includes selective nonverbal deficits, e.g., impaired visual-spatial abilities. We previously reported evidence that this phenotype results from haploinsufficiency of one or more genes on distal Xp. This inference was based on genotype/phenotype comparisons of individual girls and women with partial Xp deletions, with the neurocognitive phenotype considered a dichotomous trait. We sought to confirm our findings in a large cohort (n = 47) of adult women with partial deletions of Xp or Xq, enriched for subjects with distal Xp deletions. METHODS: Subjects were recruited from North American genetics and …