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The Effects Of Shock Waves On The Rat Fetus, Orhan Yalçin, Lütfi Tahmaz, Zuhal Yumbul, İdris Bi̇lgi̇ç Jan 1998

The Effects Of Shock Waves On The Rat Fetus, Orhan Yalçin, Lütfi Tahmaz, Zuhal Yumbul, İdris Bi̇lgi̇ç

Turkish Journal of Medical Sciences

There is an ongoing controversy regarding shock wave lithotripsy (SWL) contraindicated during pregnancy (1, 2). While the effects of shock waves on a variety of cells in both clinical and experimental studies are well documented, their effects on the fetus remain to be clarified. In this study, we investigated the effects of SWL on the rat fetus. On the 8th, 11th, 14th and 17th days of pregnancy, 100, 250 or 500 shock waves were produced with a Multimed 2001 ELMED Systems Lithotriptor. In ongoing pregnancy, the effects of SWL on fetuses ranged from mild in early pregnancy to moderate and …

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Bizarre Blood Flow Patterns Detected By Transvaginal Pulsed And Color Doppler Ultrasonography In Ectopic Pregnancies, Eyüp Eki̇ci̇, Kubilay Vi̇cdan, Muammer Doğan, Kazım Aral, Tuğrul Aydoğdu, Oya Gökmen Jan 1998

Bizarre Blood Flow Patterns Detected By Transvaginal Pulsed And Color Doppler Ultrasonography In Ectopic Pregnancies, Eyüp Eki̇ci̇, Kubilay Vi̇cdan, Muammer Doğan, Kazım Aral, Tuğrul Aydoğdu, Oya Gökmen

Turkish Journal of Medical Sciences

The characteristics of blood flow patterns detected by transvaginal pulsed and color Doppler ultrasonography were evoluated in ectopic pregnanacies. Two hundred and fifteen patients with surgically and histopathologically confirmed ectopic preg-nancies were included in this study. Of 215 patients, 113 (52.5 %) had an ectopic trophoblastic flow. 106 of them (93.8 %)showed a typical trophoblastic flow characterized by a high-velocity and low-impedance flow, whereas 7 (6.2 %) had bizarre blood waveforms including high-impedance and reversed diastolic flow. It was concluded that although most of the cases with ectopic pregnancy demonstrate a typical flow, a wide range of flow waveforms including …

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Contralateral Claustral Hemorrhage Due To A Glial Tumor, İlginç Yorulmaz, Recep Savaş, Kutsi Köseoğlu, Işıl Günhan, R.Nuri Şener Jan 1998

Contralateral Claustral Hemorrhage Due To A Glial Tumor, İlginç Yorulmaz, Recep Savaş, Kutsi Köseoğlu, Işıl Günhan, R.Nuri Şener

Turkish Journal of Medical Sciences

No abstract provided.

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Cardiac Troponin T In Diagnosis Of Acute Myocardial Infarction, Gülinnaz Alper, Ömür Erkizan, Can Hasdemi̇r, Azem Akilli, Taner Onat Jan 1998

Cardiac Troponin T In Diagnosis Of Acute Myocardial Infarction, Gülinnaz Alper, Ömür Erkizan, Can Hasdemi̇r, Azem Akilli, Taner Onat

Turkish Journal of Medical Sciences

Cardiac Troponin T (TnT) is a regulatory contractile protein not normally found in blood. Its detection in the circulation has been shown to be a sensitive and specific marker for myocardial cell damage. This study was designed to evaluate the diagnostic efficiency of TnT enzyme immunoassay for the early diagnosis of AMI (Acute Myocardial Infarction) and to compare this newly developed test with the conventionally used cardiac enzyme tests in need of an alternative test of greater sensitivity and specificity. The study population consisted of 13 patients with a mean age of 52±8 years who were hospitalized for AMI. Blood …

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Anatomy Of The Lateral Ankle Ligaments, Muzaffer Si̇ndel, Sevgi Demi̇r, Aydın Yildirim, Yaşar Uçar Jan 1998

Anatomy Of The Lateral Ankle Ligaments, Muzaffer Si̇ndel, Sevgi Demi̇r, Aydın Yildirim, Yaşar Uçar

Turkish Journal of Medical Sciences

The lateral ligaments of talocrural articulation, namely anterior talofibular ligament, posterior talofibular ligament and cal-caneofibular ligament, are important in an-atomic reconstruction. If reconstructed improperly, they are known to limit the movements of talocrural articulation and subtalar articulation (talocalcaneal articulation) Studies on anatomy of anterior talofibular ligament, posterior talofibular ligament and calcaneofibular ligament known as the lateral ligaments have some discrepancies. Knowing the importance of a more detailed discription of ankle ligament anatomy for reconstructing and fixing the ligaments, we studied 24 ankles and examined the width, length, attachment points of all three ligaments and their relationships with talocrural joint and …

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Effects Of Acute Hypothyroidism On Brainstemauditory Evoked Potentials (Baeps), Metin Özata, Abdullah Özkardeş, M. Ali Gündoğan Jan 1998

Effects Of Acute Hypothyroidism On Brainstemauditory Evoked Potentials (Baeps), Metin Özata, Abdullah Özkardeş, M. Ali Gündoğan

Turkish Journal of Medical Sciences

Although functional alterations in the central nervous system (CNS) and peripheral nerves are well documented in overt hypothyroidism, little is known about alterations of CNS in acute hypothyroidism. Sixteen patients with differentiated thyroid carcinoma were studied when prepared for radioiodine scanning after stopping levothyroxine (LT 4 ) therapy for 6 weeks to determine whether acute hypothyroidism leads to alteration in brainstem auditory evoked potentials (BAEPs). Repeat BAEPs were performed on the same patients at 6 months of the following L-T 4 therapy when patients were eu-thyroid. Neurophysiological findings were compared with a group of 20 normal controls with no hystory …

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Garnerella-Associated Vaginitis: Comparison Of Three Treatment Modalities, Şelale Özmen, Nilgün Ö. Turhan, Neslihan C. Seçki̇n Jan 1998

Garnerella-Associated Vaginitis: Comparison Of Three Treatment Modalities, Şelale Özmen, Nilgün Ö. Turhan, Neslihan C. Seçki̇n

Turkish Journal of Medical Sciences

Objective: To compare three different treatment protocols for Gardnerella va-ginalis with respect to cure rates and secondary vulvovaginal candidiasis. Methods: In this prospective randomised study, initially 2285 patients with symptoms of bacterial vaginosis were evaluated. Three hundred and seven of them in whom Gard-nerella vaginalis was recovered were eligible for the study. Group I (114 patients) was giver oral metronidazole 500mg twice daily for one week; Group II (96 patients) was prescribed oral metronidazole for one week plus a vaginal suppository of Iyophilised lactobacilli, estriol and lactose for twelve days. The third group (97 patients) was treated only with the …

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Transvaginal Color Doppler Analysis Of Benign Uterine Leiomyomas, Nuri Danişman, Eyüp Eki̇ci̇, Ahmet Z. Işik, C. Gürkan Zorlu, Oya Gökmen Jan 1998

Transvaginal Color Doppler Analysis Of Benign Uterine Leiomyomas, Nuri Danişman, Eyüp Eki̇ci̇, Ahmet Z. Işik, C. Gürkan Zorlu, Oya Gökmen

Turkish Journal of Medical Sciences

In this study, the blood flow velocity waveforms of the leiomyoma, uterine artery and myometrium with color doppler ultrasound were analyzed in patients with postoperative diagnosis of benign uterine leiomyomas and 15 healthy volunteers as a control group were enrolled into the study. The lowest RI and PI values obtained from uterine leiomyomas were 0.39 and 0.93. Mean RI and PI values obtained from uterine leiomyomas were 0.39 and 0.93. Mean RI of mometrial blood flow was 0.57, while mean PI was 0.98. These measurements were done by using the color flows that were obtained from either center visualized and …

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Cytochrome P-450 Reductase Activities In Theliver Microsomes Of Diabetic Rats Induced Withsome Chemical Solvents, Yavuz Si̇li̇ğ, Öge Çeti̇nkaya Jan 1998

Cytochrome P-450 Reductase Activities In Theliver Microsomes Of Diabetic Rats Induced Withsome Chemical Solvents, Yavuz Si̇li̇ğ, Öge Çeti̇nkaya

Turkish Journal of Medical Sciences

Cytochrome P-450 Reductase enzyme is an important enzyme providing electrons to the microsomal cytochrome P-450 enzyme system metabolizing some endogenous subtances forming in the liver, drugs, chemical carcinogens insecticides and food preservation materials. In this work, it has been attempted to determine the alterations brought about in the enzyme activities by oral administering acetone, isopropanol and ethanol to chemically induced diabetic rats. The rats in whom diabetes was induced diabetic by 65 mg/kg streptozotocin (stz) were divided into four main groups as a stz alone (group I), stz + aceton (group II), stz + isopropanol (group III), stz + ethanol …

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The Effect Of Diphtheria Toxin On Nitric Oxideinduction From Raw264.7 Murine Macrophages, Cemalettin Aybay, Gülnur Tarhan, Turgut İmi̇r, Başak Kayhan Jan 1998

The Effect Of Diphtheria Toxin On Nitric Oxideinduction From Raw264.7 Murine Macrophages, Cemalettin Aybay, Gülnur Tarhan, Turgut İmi̇r, Başak Kayhan

Turkish Journal of Medical Sciences

In this study the effect of diphtheria toxin (DT) on nitric oxide (NO) production from RAW 264.7 murine macrophages was investigated. Griess reagent was used to determine NO production by measuring nitrite levels in the culture supernatants. Corynebacterium diphtheriae G12/6 strain-produced DT (Limes flocculation activity and immunodiffusion assays were positive) demonstrated a dose-dependent effect on RAW 264.7 macrophages to induce NO production. L-NAME, an L-arginine analogue, inhibited NO production from DT-stimulated RAW 264.7 macrophages. At the given concentrations of DT, lipopolysaccharide (LPS or endotoxin)-induced NO production from RAW 264.7 macrophages was also inhibited. RAW 264.7 macrophage cells, incubated with various …

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Teratogenic Effects And The Role In The Etiologyof Atopic Diseases Of Erythrosine(Fd&C Red No.3), Onur K. Uysal, Erinç Aral Jan 1998

Teratogenic Effects And The Role In The Etiologyof Atopic Diseases Of Erythrosine(Fd&C Red No.3), Onur K. Uysal, Erinç Aral

Turkish Journal of Medical Sciences

Erythrosine (FD&C Red No.3, di sodium salt of 2,4,5,7-tetra-iodofluorescein); is used extensively as a colour additive in foods, drugs and cosmetics. Previous studies have shown that some of the food additives, depending on their long-term and short-term use, have potential carcinogenic, toxic and teratogenic effects. In Turkey this colourant has temporary permission of use until studies are completed about it. In addition food colours may cause allergic reactioins due to food intolerance. In our study 17 pregnant rats are divided into two groups: control and erythrosine group. 7 Wistar albino rats were administered 5 ml erythrosine (2mg/ml) by gavage at …

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Effect Of Acute And Regular Exercise Onantioxidative Enzymes, Tissue Damage Markersand Membran Lipid Peroxidation Of Erythrocytesin Sedentary Students, Recep Aslan, M. Ramazan Şekeroğlu, Mehmet Tarakçioğlu, Fahri Bayiroğlu, İsmail Meral Jan 1998

Effect Of Acute And Regular Exercise Onantioxidative Enzymes, Tissue Damage Markersand Membran Lipid Peroxidation Of Erythrocytesin Sedentary Students, Recep Aslan, M. Ramazan Şekeroğlu, Mehmet Tarakçioğlu, Fahri Bayiroğlu, İsmail Meral

Turkish Journal of Medical Sciences

15 healthy sedentary men, 19-25 years old an did not have any programmed physical activity, were studied. The subjects were asked to run submaximal 15-20 min every day for 5 weeks. Erythrocyte lipid peroxidation, superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) activities and glucose and uric acid levels were determined in blood samples which were taken before and immediately after acute exercise and after the end of 5-week training program. Malonaldialdehyde (MDA), sing of lipid peroxidation, creatin phosphokinase (CK), CK-MB, lactate dehydrigenase (LDH) concentrations increased (p

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The Natural Menopause Age Of Women Inerzurum And Factors Influencing The Age Atmenopause, Nesrin Rei̇s, Türkân Pasi̇nli̇oğlu, Şenol Dane Jan 1998

The Natural Menopause Age Of Women Inerzurum And Factors Influencing The Age Atmenopause, Nesrin Rei̇s, Türkân Pasi̇nli̇oğlu, Şenol Dane

Turkish Journal of Medical Sciences

In this study the age at menopause and factors influencing age at menopause were investigated by a questionnaire in 282 women. The mean age of menopause was found to be 45.3 years and ranged from 35 to 54. Positive relationships were found between age at menopause and marital satus, body mass index, gravidity, parity, age at menarche, menstruation and menstruation bleeding period. Whereas negative relationships were found between age at menopause and smoking, age at first birth, abortion status and oral contraceptive use.

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A Probable Case Of Men1 Syndrome Presentingwith Intractable Peptic Ulcer Disease Andepisodic Confusion, Şükrü Palanduz, Cemil Taşçioğlu, Nilgün Erten, Mehmet Akif Karan, Kıvanç Çefle, Kerim Güler, Oğuz Öztürk, Şükrü Öztürk Jan 1998

A Probable Case Of Men1 Syndrome Presentingwith Intractable Peptic Ulcer Disease Andepisodic Confusion, Şükrü Palanduz, Cemil Taşçioğlu, Nilgün Erten, Mehmet Akif Karan, Kıvanç Çefle, Kerim Güler, Oğuz Öztürk, Şükrü Öztürk

Turkish Journal of Medical Sciences

No abstract provided.

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Neuronal Differentiation In The Cerebral Cortexof The Rat: A Golgi-Cox Study, Necdet Demi̇r, Ramazan Demi̇r Jan 1998

Neuronal Differentiation In The Cerebral Cortexof The Rat: A Golgi-Cox Study, Necdet Demi̇r, Ramazan Demi̇r

Turkish Journal of Medical Sciences

The development of cerebral cortex neurons has been studied in different stages of pre- and postnatal periods of rats. In order to show the neuronal processes, the Golgi-Cox impregnation technique was used. The first neuronal process development was observed in the cranial and caudal poles of the cerebral cortex during the 15th prenatal day and continued spreading from the lateral regions and poles towards the dorsocentral regions of the hemispheres. The cells which showed the first impregnation in the cerebral cortex, were bipolar cells and their bodies were located in the deep regions of the hemisphere wall. Primitive multipolar cells, …

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Tracheopathia Osteoplastica, Adil Zamani, Ayşe Gül Zamani, Ergün Bikmaz, Oktay İmeci̇k Jan 1998

Tracheopathia Osteoplastica, Adil Zamani, Ayşe Gül Zamani, Ergün Bikmaz, Oktay İmeci̇k

Turkish Journal of Medical Sciences

No abstract provided.

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Characterisation Of A Polyclonal Antiserumagaints Ubiquitin And Its Use In The Investigationof Ubiquitin Conjugate Distribution In Normaland Stressed 3t3-Li Cells, İbrahim Pi̇ri̇m Jan 1998

Characterisation Of A Polyclonal Antiserumagaints Ubiquitin And Its Use In The Investigationof Ubiquitin Conjugate Distribution In Normaland Stressed 3t3-Li Cells, İbrahim Pi̇ri̇m

Turkish Journal of Medical Sciences

Antiserum against ubiquitin was used to identify ubiquitin conjugates in 3T3- LI cells, and to investigate changes in the amount and distribution of these conjugates in cells subjected to stress. Stress was induced by incubation with canavanine, an amino acid analogue, and by exposure of cells to temperatures of 43°C (heat shock). SDS-PAGE, followed by immunoblotting, produced no observable change in ubiquitin conjugation with the canavanine as used in this protocol.Heat shock, in a variety of different exposure protocols, appeared to produce an increase in a wide spectrum of ubiquitin conjugates of molecular weight>70kd. The conjugates wereresent in the …

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Metabolic Effects Of Isradipine In Normotensiveniddm Patients With Microalbuminuria, Tevfik Sabuncu, Hüseyin Vural, Mahmut Dalmaz, Yaşar Nazligül, Abdurrahim Koçyi̇ği̇t, Özcan Erel, Şenel Avci Jan 1998

Metabolic Effects Of Isradipine In Normotensiveniddm Patients With Microalbuminuria, Tevfik Sabuncu, Hüseyin Vural, Mahmut Dalmaz, Yaşar Nazligül, Abdurrahim Koçyi̇ği̇t, Özcan Erel, Şenel Avci

Turkish Journal of Medical Sciences

The aim of this study was to determine whether isradipine affects microalbuminuria and other biochemical parameters related to glucose and lipid metabolisms. 18 subjects, 40 to 73 years of age, with NIDDM for 0 to 21 years, blood pressure²140/90 mmHg in the absence of antihypertensive treatment, and persistent urinary albumin excretion rate (UAER) 30 to 300 mg/day, received sustained-release (SRO) formulation isradipine at dosages of 5 mg once daily for 3 months. The effects of isradipine on microalbuminuria, fasting plasma glucose, plasma lipids, plasma creatinin, uric acid, C-peptide, insulin, HbA 1c , fructosamine, systolic and diastolic blood pressure and heart …

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Changes In Blood Antioxidant Status And Lipidperoxidation Following Distance Running, Mustafa Kelle, Hüda Di̇ken, Abdurrahman Sermet, Mukadder Atmaca, Yüksel Koçyi̇ği̇t Jan 1998

Changes In Blood Antioxidant Status And Lipidperoxidation Following Distance Running, Mustafa Kelle, Hüda Di̇ken, Abdurrahman Sermet, Mukadder Atmaca, Yüksel Koçyi̇ği̇t

Turkish Journal of Medical Sciences

To examine the effects of increased O 2 utilization on blood antioxidant status and lipid peroxidation, ten trained male athletes took part in a 20 km distance race. Venous blood samples were removed before and immediately after completion of the half-marathon. Plasma creatine kinase (CK) activity, an index of muscle damage, increased (p

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Eating Induced By Perifornical Camp Is Behaviorally Selective And Involves Protein Kinase Activity, Gillard, Arshad Khan, Bara Mouradi, Omkar Nalamwar, B. Stanley Jan 1998

Eating Induced By Perifornical Camp Is Behaviorally Selective And Involves Protein Kinase Activity, Gillard, Arshad Khan, Bara Mouradi, Omkar Nalamwar, B. Stanley

Departmental Papers (Biology)

No abstract provided.

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Diabetic Complications In Experimental Models, Yusuf Öztürk, V. Melih Altan, Nuray Ari Jan 1998

Diabetic Complications In Experimental Models, Yusuf Öztürk, V. Melih Altan, Nuray Ari

Turkish Journal of Medical Sciences

In this review, the aim is to focus on diabetic complications in experimental models of diabetis. For this purpose, com-plications, chiefly seen in log-term periods in various systems of animals, such as cardio vascular and nervous systems, gastrointestinal, urogenital and respiratory tracts, etc., have been stated. Furthermore, novel and conventional therapeutic approaches in their management have also been briefly discussed.

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Global Ischemia And Turn Preference; Acomparative Study Of The Effects Of Globalischemic Insult In Rats, Akçahan Gepdi̇remen, Cemal Gündoğdu, Sinan Sönmez, Dilek Sadeler, Halis Süleyman, Mehmet Emin Büyükokuroğlu Jan 1998

Global Ischemia And Turn Preference; Acomparative Study Of The Effects Of Globalischemic Insult In Rats, Akçahan Gepdi̇remen, Cemal Gündoğdu, Sinan Sönmez, Dilek Sadeler, Halis Süleyman, Mehmet Emin Büyükokuroğlu

Turkish Journal of Medical Sciences

We examined the effect of global cerebral ischemia (Two vessel occlusion plus systemic hypotension method) for 15 minutes on the hippocampal CA1 and CA3 neurones in rats, and compared with turn prefence scores. 14 of 27 animals were ambidexter while 9 had left and 4 had right turn preference. The left turns were significantly different from rights (t:2,26 df:26 p:0,032). Male rats prefered 62,73% and females 56,88% left turns. Forty-eight hours following the global cerebral ischemic insult, animals were sacrificed and brains were examined by using light microscope. Hippocampal neurones of the right hemisphere were survived more in males while …

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Renal Ultrastructural Alterations Followingadministration Of Diethylstilbestrol, Bilge Onarlioğlu, Yasemin Günay, İsmihan Göze, Emel Koptagel Jan 1998

Renal Ultrastructural Alterations Followingadministration Of Diethylstilbestrol, Bilge Onarlioğlu, Yasemin Günay, İsmihan Göze, Emel Koptagel

Turkish Journal of Medical Sciences

Diethylstilbestrol (DES), nonsteroid in structure, is an artificial estrogen derivative and is used as an anabolic agent. It is known that diethylstilbestrol causes genetic disorders and toxic effects leading up to carcinoma even in amounts below its residual levels. For this purpose, a dose of 60µm/kg/day of DES dissolved in 0,1 ml corn oil has been administered to rats by oral gavage for varying periods of 20, 50 and 100 days periods. Rat renal tissue samples, following routine electron microscopical procedure, have been examined by transmission electron microscopy. Following diethylstilbestrol administration, glomerular capilleries seemed dilated along with occasional basement membrane …

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The Role Of Serum On The Adhesion Of Culturedchinese Hamster Lung (Chl) Cells, Ali Yildirim Jan 1998

The Role Of Serum On The Adhesion Of Culturedchinese Hamster Lung (Chl) Cells, Ali Yildirim

Turkish Journal of Medical Sciences

The roles of serum on the initial attachment and adhesion strength of CHL cells, which is gained following initial attachment, spreading and growth, on tissue culture polystyrene dish were determined by using a convergent Microflow chamber. In the presence of 10% fetal calf serum 98%±2% of cells were attaching within 2 hours at 37°C. While only 74%±3% of cells were attaching during the same period of incubation in serum free medium. The critical shear stresses of detachment of CHL cells were 3.01±0.25 Nm -2 , 5.38±0.55 Nm -2 , 7.22±0.54 Nm -2 , 9.47±0.43 Nm -2 , and 9.54±1.15 Nm …

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The Effect Of Tamoxifen On The Neonataldevelopment Of Rat Penis, Engin Deveci̇, Yusuf Nergi̇z, Serap İnalöz, Murat Akkuş, M. Aydın Ketani̇, A. Reşit Ersay Jan 1998

The Effect Of Tamoxifen On The Neonataldevelopment Of Rat Penis, Engin Deveci̇, Yusuf Nergi̇z, Serap İnalöz, Murat Akkuş, M. Aydın Ketani̇, A. Reşit Ersay

Turkish Journal of Medical Sciences

In rats penis development a seen two stages in prenatal life, the second stage is androgen hormone dependent chondrocyte and osteocyte differentiation period. To investigate Tamoxifane (Tx) administration on the developmental anomalies of penis. The newborn male rats were injected with 100 µg Tamoxifen subcutaneously from the day of birth to fifth day. This changes in Os penis and glans penis were investigated after the rats had been sacrificed and their penis were removed on the days 14.0, 21.0, 28.0, 35.0 and 60.0 Having been fixed in neutral formaline of 10%, the totally taken penis werembedded into paraffin blocks. The …

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Incidence Of Listeria Spp. From Raw Milk In Sivas, Gülhan Vardar-Ünlü, Mehmet Ünlü, Mustafa Zahir Bakici Jan 1998

Incidence Of Listeria Spp. From Raw Milk In Sivas, Gülhan Vardar-Ünlü, Mehmet Ünlü, Mustafa Zahir Bakici

Turkish Journal of Medical Sciences

Raw milk samples obtained from the Foundation of Milk Industry, three private dairy companies and individual dairy farms in Sivas, were tested for the presence of Listeria species. A total of 100 raw milk samples were analysed by Food and Drug Administration (FDA) and two-stage enrichment techniques. Two-stage enrichment procedure was found to be more effective than FDA method in isolating Listeria species from raw milk. The overall incidence of Listeria species in raw milk was 6%. Listeria monocytogenes was found in 4% of the raw milk samples, while L. innocua was found in 2% of the samples. One sample …

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The Inhibitory Effect Of Zinc On Imipenem Andmeropenem Susceptibility Of Pseudomonasaeruginosa, Selahattin Atmaca, Ramazan Çiçek, Kadri Gül Jan 1998

The Inhibitory Effect Of Zinc On Imipenem Andmeropenem Susceptibility Of Pseudomonasaeruginosa, Selahattin Atmaca, Ramazan Çiçek, Kadri Gül

Turkish Journal of Medical Sciences

In this study we have showed that zinc ion has an inhibitory activity on imipenem and meropenem suspectibility of Pseudomonas aeruginosa. When zinc ion concentration of Mueller-Hinthon agar (MHA) media was gradually increased the zone diameters of imipenem and meropenem gradually decreased. So we concluded that zinc concentration in the media might effect imipenem and meropenem susceptibility of Pseudomonas aeruginosa and might indicate false resistance to imipenem and meropenem. Therefore the use of these antipseudomonal antibiotics in Pseudomonas infections may be restricted.

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Iridoid And Lignan Glucosides From Bellardiatrixago (L.) All., Tayfun Ersöz, Funda Nuray Yalçin, Deniz Taşdemi̇r, Otto Sticher, İhsan Çaliş Jan 1998

Iridoid And Lignan Glucosides From Bellardiatrixago (L.) All., Tayfun Ersöz, Funda Nuray Yalçin, Deniz Taşdemi̇r, Otto Sticher, İhsan Çaliş

Turkish Journal of Medical Sciences

Five iridoid glucosides aucubin (I), bartsioside (II), melampyroside (III), mussaenoside (IV) and gardoside meathyl ester (V) as well as the lignan glucoside dehydrodiconiferyl alcohol-4- 0-\beta-D-glucoside (VI) were isolated from the overground parts of Bellardia trixago.The structure elucidation of the isolated compounds (I-VI) was realized on the basis of spectral evidence (UV, IR, 1 H and 13 C NMR) and the results were confirmed by comparison of the isolated compounds with authentic samples on TLC.

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Morphology Of The Human Cuneus Bymagnetic Resonance Imaging, Figen Gövsa, Gülgün Kayalioğlu, Orhan Oyar, Özlem Taşkiran, Tuncay Varol Jan 1998

Morphology Of The Human Cuneus Bymagnetic Resonance Imaging, Figen Gövsa, Gülgün Kayalioğlu, Orhan Oyar, Özlem Taşkiran, Tuncay Varol

Turkish Journal of Medical Sciences

Variations of the limiting and internal sulci of the human cuneus was studied using magnetic resonance imaging (MRI) on 209 healthy individuals and the sulcal pattern of the right hemispheres of both sexes were evaluated. The internal sulci were divided into supreme, superior, middle and inferior sulci. Sulci were classified according to their localizations, courses, and terminations. Cuneus angle was measured and found as 68.84±9.74° and no sex differences was found for this angle.

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Investigation Of The Inhibition Effects Of Someantibiotics On Human Erythrocytecarbonic Anhydrase Isozymes, T. Abdülkadir Çoban, Barbaros Nalbantoğlu, M. Yaşar Çi̇l, Hasan Özdemi̇r, Ö. İrfan Küfrevi̇oğlu Jan 1998

Investigation Of The Inhibition Effects Of Someantibiotics On Human Erythrocytecarbonic Anhydrase Isozymes, T. Abdülkadir Çoban, Barbaros Nalbantoğlu, M. Yaşar Çi̇l, Hasan Özdemi̇r, Ö. İrfan Küfrevi̇oğlu

Turkish Journal of Medical Sciences

In this study, the in vitro effects of some antibiotics on carbonic anhydrase (CA) isozymes have been investigated. Human erythrocyte CA-I and CA-II isozymes were separately purified by affinity chromatography. Inhibition effects of four different antibiotics on CA isozymes were determined by using the CO 2 -Hydratase method. I 50 values of antibiotics were obtained by drawing % Activity [Actibiotic] graphs. The obtained I 50 values of cefazolin sodium, cephradine, sulbactam/cefoperazone and chloramphenicol sodium succinate were 9, 16, 19 and 48 mM on CA-I and 6, 10, 15 and 17 mM on CA-II, respectively. Antibiotics dosages should be taken into …

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